About the Role

We are seeking a Senior Commercial Program Manager to drive operational excellence across the Commercial organization. This role will focus on building scalable processes, improving cross-functional workflows, and ensuring consistent operating rhythms that enable the business to execute effectively against revenue goals.

The ideal candidate combines strong analytical thinking with pragmatic execution skills. They are highly organized, comfortable working across multiple stakeholders, and skilled at translating business priorities into structured processes, clear metrics, and efficient workflows to increase speed, predictability, and efficiency.

This individual will work closely with commercial leadership to run our operating cadences, eliminate friction across cross-functional workflows, and build the infrastructure that lets the business scale. 

Key Responsibilities

Process Design & Workflow Optimization

• Evaluate existing commercial workflows and identify opportunities to streamline processes and reduce friction in partnership with the Commercial team
• Design and implement scalable processes that improve efficiency
• Standardize documentation, handoffs, and communication channels to improve cross-functional alignment
• Reduce manual work and improve repeatability of core commercial processes

Metrics, Reporting & Insights

• Partner with Analytics  to define and maintain key commercial metrics
• Analyze performance trends to identify opportunities for improvement
• Ensure leadership has clear visibility into pipeline health, performance against goals, and operational risks
• Translate data into actionable insights that support decision-making

Cross-Functional Program Leadership

• Drive alignment across Commercial and Operations teams
• Support execution of key commercial initiatives and strategic priorities
• Ensure dependencies are clearly identified and managed
• Help teams stay organized and focused on delivering outcomes

Continuous Improvement

• Identify structural issues that slow execution or create ambiguity
• Proactively propose solutions that improve clarity, accountability, and speed
• Build frameworks that scale with company growth
• Serve as a thought partner to commercial leadership on operational improvements

Commercial Operating Rhythm

• Support the execution of cadences across the Commercial organization, including leadership meetings, quarterly planning, and goal tracking
• Ensure agendas, priorities, and action items are clearly defined and followed through
• Identify opportunities to improve meeting effectiveness and decision-making clarity
• Help leadership maintain focus on highest-impact initiatives

Qualifications

Required

• 6–10 years of experience in program management, business operations, strategy & operations, or commercial operations
• Demonstrated experience improving business processes and operational workflows
• Strong organizational skills and attention to detail
• Experience working with leadership teams to drive execution against strategic priorities
• Strong analytical skills and comfort working with metrics and dashboards
• Excellent communication skills, including ability to synthesize complex topics clearly
• Ability to influence without authority across multiple stakeholders
• Experience supporting structured operating cadences

Preferred

• Experience supporting Sales, Marketing, or Customer Success organizations
• Familiarity with CRM and analytics tools (e.g., Salesforce, HubSpot, Looker)
• Experience working in high-growth or scaling organizations

About the Role

The Regional Director is responsible for owning and optimizing site-level performance across a portfolio of GI-focused clinical research sites. This role ensures operational excellence by aligning teams around key performance goals, elevating site capabilities, and maintaining consistency in trial execution. As a strategic operations leader, the Regional Director plays a central role in connecting site level performance with broader business objectives.

Responsibilities

• Manages staff across multiple sites, ensuring execution is aligned with protocol, regulatory requirements, and IH standards.
• Owns overall performance of assigned sites, including enrollment, data quality, compliance, and team culture.
• Ensures sites are set up for success (i.e. staffed appropriately and equipped with the appropriate equipment and training) and makes recommendations to allocate resources based on business needs. 
• Builds strong relationships and collaborates with PIs to align their engagement with study goals and operational strategy.
• Influences study portfolio, optimizing for profitability and value to patients. 
• Identifies and manages issues, concerns and problems related to site performance.
• Leads and develops CRCs, and other site-based research staff through clear expectations, performance coaching, and team development.
• Serves as a visible, hands-on people manager who builds high-performing, accountable teams.
• Identifies levers to drive site level KPIs through monitoring KPIs and performance trends, escalating to appropriate parties. 
• Implements corrective actions or process improvements as needed.
• Serves as the primary operational liaison between site staff and central functions.
• Drives a culture of ownership, collaboration, and continuous improvement across all assigned sites.

What We’re Looking For

Required Qualifications

• Knowledgeable about the critical elements for success in clinical trials: Ability to review protocols, programs, and assess the success of a project.
• Ability to influence change management and model flexibility
• Problem-Solving Skills: Ability to identify problems, develop and implement solutions.
• Strategic Planning: Ability to plan for short, medium and long term success and make recommendations for growth
• Ability to use data as a tool, identify trends, and draw conclusions. 
• Project Management: Demonstrated ability to successfully manage people/projects.
• Proactive problem-solving abilities and follow-through.
• Practices professionalism and integrity in all actions. 
• Communication Skills: Excellent written and verbal communication skills. 
• Working knowledge of CTMS, eDC and other core research systems. 
• Ability to travel: Up to 30% travel to provide operational oversight, hold team meetings, and attend other professional meetings/conferences as needed.

Preferred Qualifications

• Experience in managing a large site network and demonstrated success in achieving targets and optimizing operations.
• Experience with gastroenterology and/or hepatology studies. 

What We Offer

• Medical, dental, and vision insurance
• Life and disability insurance
• Parental leave
• Stock options
• Flexible work hours
• Unlimited paid time off

About the Role

We are seeking a highly organized and experienced Accounts Receivable (AR) Manager to lead our AR operations with a focus on clinical research projects. The ideal candidate will have 5+ years of AR experience, including NetSuite proficiency, a strong background in collections management, and expertise in long-term, milestone-based contracts with partial payment structures. Experience in Real Time software and advanced Excel capabilities are also essential.

Location: Cambridge, MA

Responsibilities

Accounts Receivable & Collections Management:

• Run monthly AR reports, consolidate and prepare global aging by customer, location and business.
• Develop and maintain executive AR dashboards including aging, DSO and other AR KPIs.
• Manage the AR reconciliation process between the GL and Real Time
• Partner with project management and contract teams to align invoicing and collections with project milestones.
• Review and propose AR reserves.
• Prepare collections forecast reports.

• Leverage NetSuite to manage AR operations and generate financial reports.
• Use Real Time software to help track project data and integrate AR activities where appropriate.
• Ensure timely and accurate application of customer payments against open invoice within NetSuite.
• Oversee all AR functions including billing, invoicing, cash applications, and collections from an accounting perspective, partnering with the RCM team to ensure clinical research related receivables are properly recorded and reconciled.
• Manage collections for long-term contracts that include milestone-based and partial payments.

Team Leadership & Process Optimization:

• Supervise, mentor, and develop the AR function, coordinating with the RCM team as needed to improve performance and efficiency.
• Establish KPIs for the AR function and drive process improvements to reduce aging and bad debt exposure.
• Collaborate with other departments including Finance, Project Management, and Legal to resolve billing issues and support customer relationships.
• Lead AR-related audits and prepare supporting documentation as needed.

Industry-Specific Focus:

• Apply knowledge of clinical research billing practices and revenue cycle requirements.
• Ensure AR practices align with clinical study timelines, contracts, and regulatory requirements.

• Collaborate with other team members to ensure accurate financial reporting and support cost analysis initiatives.

What We’re Looking For

Required Qualifications

• Education: Bachelor’s degree in Accounting, Finance, or Business Administration.
• Experience: 5+ years of progressive AR/accounting experience, with at least 2 years in a managerial or supervisory role.
• Minimum 2 years of experience working within the healthcare industry.
• Proven track record managing collections on milestone-based contracts with partial payment structures.
• Experience in clinical research industry AR is required.
• Proficient in NetSuite and Real Time software.
• Strong knowledge of Microsoft Excel (pivot tables, VLOOKUP, etc.).

Preferred Qualifications

• Exceptional attention to detail and organizational skills.
• Strong analytical and problem-solving abilities.
• Excellent communication and interpersonal skills.
• Ability to work independently and collaboratively in a fast-paced environment.

​​Cloud Engineer is a key role as this will automate, evolve, and establish a scalable cloud platform across the company optimizing for self-service and governance. The role will work with both Cloud Native platforms Azure and AWS, leverage tools like Kubernetes (AKS), and Cloud Hosting providers offerings like IaaS, PaaS, and SaaS ensuring consistent experience and high standards are established.

What will you do?

​​Maintain Microsoft Azure cloud infrastructure​ 

• ​​Utilize best practices to ensure backup and recovery techniques for applications on Azure platform. 
• ​Supporting and maintaining Azure cloud infrastructure 
• ​Implementing deploying workloads on Azure virtual machines 
• ​Container technologies i.e. Kubernetes & AKS  
• ​Utilize Terraform code to deploy multiple resource groups, VMs, and VNETs 
• ​Upgrading version and certificates  
• ​Load Balancers, AzurePolicies, AzureKayVault and Tagging 
• ​Expertise in Microsoft Azure Cloud services (SaaS, PaaS and IaaS) 
• ​Monitoring Azure infrastructure and logs 

​​Maintain Azure cloud AKS​  

• ​​Administration of AKS clusters 
• ​Configuring web apps, Azure App services, Azure DNS, Azure traffic manager, App services and Azure Application gateway, 
• ​Managing the Azure Kubernetes Services policies, providing access to different Azure resources ​managing secrets, firewalls, PODS, containers. 
• ​Injecting data in applications  
• ​Troubleshooting cluster related issues
• ​Cluster AutoScaler and load balancers for Azure Kubernetes Service (AKS) using Terraform and worked with scheduling deploying, and managing pods and replicas in AKS
• Working knowledge in deploying CI/CD system using Azure DevOps and Kubernetes container environment​ 

Azure Automation

• ​​Good knowledge of building and supporting CI/CD pipelines using Azure DevOps 
• ​Creating Ansible play books, Dockers and Jenkins 
• ​Working knowledge on json, yaml, Terraform and Helm chart​ 

After-Hours Support 

• Participate on an on-call rotation and be available for out of office hours support when needed 

What will you need to succeed? 

• Undergraduate degree in Information Technology with MS or AWS Cloud Certification desirable
• 3-5 years of hands-on experience in Azure AKS
• Minimum 3 years of good knowledge in building and supporting CI/CD pipelines using Azure DevOps
• Minimum 4 years Azure Cloud Platform
• Minimum 2 years Azure DevOps experience
• Proficient in Administrating Azure laaS/PaaS, Azure Virtual Machines, VNET, Network services, Azure DevOps,
• Hands on experience on SQL Databases, Storages, AzureActive Directory, Monitoring, Autoscaling,
• Hands on experience in Azure Blueprint, Azure Site Recovery and Azure backup
• PowerSheII Automation, Azure Search, DNS,VPU extensive
• 4+ years’ working experience of Azure SQL and Cloud platform
• Strong understanding of Terraform
• Hands on experience on Load Balancers, AzurePolicies, AzureKayVault and Tagging
• Expertise in Microsoft Azure Cloud services (SAAS, PASS and IAAS)
• Monitoring Azure infrastructure and logs
• Strong knowledge of Azure Networking, Azure Virtual Machines, Azure Active Directory
• Experience with Load Balancers, AzurePolicies, AzureKayVault and Tagging
• Experience with Cloud and other traditional monitoring technologies, as well as hands on experience instrumenting alerts based on aggregated logs and analytics output.

#LI-Hybrid

The expected base salary range for this position is $64,500 - $114,500. Depending on your relevant experience, skills, qualifications, market conditions and business needs, base compensation may vary. Please note: This range reflects the expected base salary for this role but may not represent the full compensation range for all experience and skill levels. During the recruitment process, we will discuss and consider how your unique qualifications align with the broader range for this position.

The Position

Reporting to our Co-CEO’s, the SVP of Program Leadership & Development will drive the advancement of our clinical-stage pipeline. This individual will be responsible for end-to-end leadership of one or more key development programs translating scientific innovation into clinical, regulatory, and commercial success.

The SVP of Program Leadership & Development will play a critical role in shaping program strategy, guiding cross-functional execution, and maximizing asset value from early development through late-stage trials and potential regulatory approval.

This role will serve as a core member of the Senior Leadership Team, partnering closely with Clinical Operations, Medical, Regulatory, Biometrics, CMC, Commercial and other functional leaders to drive the successful execution of Amylyx’s development portfolio.

In a lean and evolving biotech environment, this individual will operate both as an enterprise leader and a hands-on program leader, directly supporting key assets while building a scalable program leadership organization over time.

The Opportunity

This is a unique opportunity to shape and define how program leadership is executed within a growing biotech organization at a critical inflection point.

Build a New Function from the Ground Up - design and implement a modern program leadership model, including the evolution from traditional program management to a strategic Program Lead and Program Manager structure.

Operate as a True Peer to Clinical and Medical Leadership - serve as an equal partner to senior leaders across Clinical Operations, Medical, and Regulatory, helping shape asset strategy and execution.

Drive Impact Across the Full Development Lifecycle - lead programs spanning early-phase IND-enabling work through Phase 3 and potential NDA submission, with direct impact on key value-driving milestones.

Balance Strategy and Execution in a Lean Environment - play a dual role as both a strategic leader and hands-on program leader, directly influencing outcomes while building for future scale.

Shape Organizational Culture and Ways of Working - establish a highly collaborative, accountable, and transparent operating model that strengthens alignment across functions and reduces organizational friction.

Scale with the Portfolio - build and develop a high-performing team over time, aligned to the growth of the pipeline and key clinical milestones.

Responsibilities

Strategic Program Leadership

• Partner with Clinical Operations and Medical leadership to define and execute development strategies and plans across programs
• Drive program-level decision-making, including risk assessment, trade-offs, and prioritization
• Ensure alignment between asset strategy, clinical execution, and regulatory pathways
• Present program updates, risks, and opportunities to Executive Leadership and Board of Directors

Cross-Functional Integration & Alignment

• Serve as the central integrator across Medical, Clinical Operations, Regulatory, Biometrics, CMC, Commercial and other key functions
• Drive clarity of roles, decision-making, and accountability across program teams
• Proactively identify and resolve cross-functional misalignment, gaps, and competing priorities

Hands-On Program Execution

• Directly serve as Program Lead for one or more key assets, particularly in the early phase of the role
• Lead cross-functional team meetings, execution planning, and milestone delivery
• Translate strategic objectives into clear, aligned execution plans

Build & Scale Program Leadership

• Design and implement a program leadership model, including Program Leads and Program Managers
• Hire, develop, and lead program leadership talent over time as the organization grows
• Establish best practices, governance frameworks, and ways of working that enable scalability

Portfolio & Executive Contribution

• Contribute to portfolio prioritization, resource allocation, and strategic planning discussions at the leadership level
• Provide clear, actionable insights and recommendations to executive leadership
• Support the evolution of Amylyx’s development organization as it scales toward key clinical and regulatory milestones

Required Qualifications

• Advanced degree (PhD, MD, PharmD, or MD) in a relevant scientific discipline preferred; equivalent experience in drug development and program leadership will also be considered
• 20+ years of experience in the pharmaceutical or biotechnology industry, including significant experience leading cross-functional drug development programs
• Lead integrated clinical development plans (CDPs)
• Overseen protocol design, endpoints, and trial execution
• Demonstrated success in regulatory interactions (FDA, EMA)
• Significant experience leading cross-functional drug development programs, ideally spanning early development through late-stage clinical and/or regulatory milestones
• Demonstrated success in regulatory interactions (FDA, EMA)
• Prior experience serving as a Program Lead, Development Team Leader (DTL), Asset Team Lead or equivalent role, with accountability for cross-functional program execution
• Demonstrated ability to partner with Clinical Operations, Medical, and Regulatory leaders as a peer, influencing strategy and execution
• Experience operating in a biotech or similarly lean, fast-paced environment, with comfort navigating ambiguity and evolving priorities
• Proven track record of building or scaling teams and/or functions within a matrixed organization
• Strong leadership and collaboration skills, with the ability to align diverse stakeholders and drive decision-making in complex environments
• Hands-on, execution-oriented leadership style, with willingness to engage directly in program delivery when needed
• Excellent communication and interpersonal skills, with the ability to bridge scientific, clinical, and business perspectives

Work Location and Conditions

• At Amylyx, we proudly support remote work opportunities within the United States. However, due to business considerations candidates must be able to attend meetings at our office in Cambridge, MA on a regular basis.  Preference will be given to candidates who reside in the New England region and can be in person on an as needed basis. Currently, we are not considering applicants from Alaska, Arizona, Hawaii, Michigan and Tennessee.
• When working remotely, you must have access to a work setting which enables meeting all requirements of the role (including privacy, reliable internet access, phone, ability to video conference, etc.) at your remote location.

About Graphcore 

At Graphcore, we’re building the future of AI compute.

We’re a team of semiconductor, software and AI experts, with deep experience in creating the complete AI compute stack - from silicon and software to infrastructure at datacenter scale.

As part of the SoftBank Group, backed by significant long-term investment, we are delivering key technology into the fast-growing SoftBank AI ecosystem.

To meet the vast and exciting AI opportunity, Graphcore is expanding its teams around the world.

We are bringing together the brightest minds to solve the toughest problems, in a place where everyone has the opportunity to make an impact on the company, our products and the future of artificial intelligence

Job Summary

As a member of the drivers and utilities team you will contribute to the planning, design, implementation and testing of low level kernel drivers and user space driver library code. You will be part of one of the two teams in the system software department (the firmware team being the other one) and report to the drivers and utilities team manager.  

The Team

The drivers and utilities team forms part of the system software group – working closely with both software engineers developing our Poplar SDK and with silicon and hardware engineers developing Graphcore’s IPU solution. The drivers and utilities team develop custom control software on the host in kernel and user space. Our solutions enable our customers to get maximum performance and utility for our cutting-edge products.  

Responsibilities and Duties

• Design, implement, test and document OS Kernel and Device Driver software at the highest standard using C/C++/Python programming languages
• Participate in agile development – working as part of a scrum team to develop the right software at pace
• Communicate effectively and contribute regularly to technical discussions with your peers in software and hardware engineering, with architects and other stakeholders
• Hands-on during key product development phases involving close working with hardware and silicon engineering groups to enable fast time to market delivery

Candidate Profile

Essential:

• Proven industry experience in software development using programming languages such as C/C++/Python
• OS Kernel and Device Driver development and deployment experience in Linux or Windows systems
• Good understanding of lower-level software stack and interactions with the hardware layer
• Possess effective problem-solving skills, familiar with a full suite of debug and performance analysis tools and techniques
• Experience with one or more of the following: PCIe, CPU, device drivers, SoC, firmware, and hardware/software integration
• Proactive in obtaining engineering or management input to solve issues
• Motivated to schedule own workload
• Excellent written and verbal communication skills, work well within a multinational team and with multinational customers. Excellent cultural awareness is essential. 

Desirable

• Experience developing firmware or drivers for GPUs. 
• Knowledge of CUDA or OpenCL  
• Experience working on upstreaming of kernel code / contributing to Linux kernel.
• Exposure to integration with data centre / cloud service operations – for example integration with Kubernetes or open stack. 

Benefits

In addition to a competitive salary, Graphcore offers flexible working, a generous annual leave policy, private medical insurance and health cash plan, a dental plan, pension (matched up to 5%), life assurance and income protection. We have a generous parental leave policy and an employee assistance programme (which includes health, mental wellbeing, and bereavement support). We offer a range of healthy food and snacks at our central Bristol office and have our own barista bar! We welcome people of different backgrounds and experiences; we’re committed to building an inclusive work environment that makes Graphcore a great home for everyone. We offer an equal opportunity process and understand that there are visible and invisible differences in all of us. We can provide a flexible approach to interview and encourage you to chat to us if you require any reasonable adjustments.

Applicants for this position must hold the right to work in the UK. Unfortunately at this time, we are unable to provide visa sponsorship or support for visa applications

About Graphcore

At Graphcore, we’re building the future of AI compute.We’re a team of semiconductor, software and AI experts, with deep experience in creating the complete AI compute stack - from silicon and software to infrastructure at datacenter scale.As part of the SoftBank Group, backed by significant long-term investment, we are delivering key technology into the fast-growing SoftBank AI ecosystem.To meet the vast and exciting AI opportunity, Graphcore is expanding its teams around the world.We are bringing together the brightest minds to solve the toughest problems, in a place where everyone has the opportunity to make an impact on the company, our products and the future of artificial intelligence.

Job Summary 

As a Senior Technical Project Manager focussed on Platform you will play a key role in bridging the technical and management domains of teams responsible for the planning and delivery of solutions for workload management, systems management & observability, integrated hardware/software quality assurance and cloud development.

You will collaborate with highly technical engineering leads, and multi-functional teams across systems, software, operations, and product to support the flawless delivery of our fully integrated hardware and software AI systems.

Responsibilities and Duties

• Serve as the primary liaison for the technical teams in multi-functional discussions, ensuring alignment on project requirements.

• Support the planning, development and management of project schedules and deliverables to achieve programme objectives on schedule.
• Ensure each team’s programme deliverables satisfy requirements and are fulfilled by the engineering work.
• Monitor and track dependencies both within Platform and with other programme teams, communicating any near-term inputs for the individual team backlogs.

• Represent Platform in programme management syncs and reviews. Efficiently aid teams’ navigation of scope changes to minimize impacts on project timelines and outcomes.

• Work with Release Management and Engineering teams to minimise time-to-delivery and remove blockers for developing at scale.
• High-level technical understanding of the software, QA, cloud development solutions so that you can contribute meaningfully to priority discussions.

• Proactively identify risks and dependencies, support the teams’ development of mitigation strategies, and inform/escalate issues.
• Provide regular updates on program status, highlighting challenges and proposing solutions to internal partners, facilitating informed decision-making.

• Facilitate process for internal compute resource allocations among engineering teams.

• Continually improve processes, optimize workflow, and maintain the highest quality levels.

Skills and Experience

Essential:

• Bachelor's degree in a relevant subject or equivalent experience.
• Experience of working in programs with a strong software and hardware mix.
• Track record of working with Agile project development practices.
• Excellent communicator, translating complex situations into plain narrative.
• Outstanding facilitator to help resolve complex issues.
• Great organiser of people, processes, and product plans.
• Experience working with Atlassian tools (Jira, Confluence) to represent complex work hierarchies and dependencies.
• An ability to work independently without daily oversight in projects that can rapidly evolve and change.
• A demonstrable understanding and application of knowledge and skills managing dependencies, priorities, risks, issues, impacts and constraints.
• A proven track record of delivering technical output, perhaps as an individual contributor, manager or project manager, especially in software development.

Desirable:

• Minimum of 8 years of relevant experience including at least 3 years in a technical program management role, ideally within multi-functional teams.
• Understanding of AI or HPC systems and how each component interacts with the system.
• Knowledge of data centre design, infrastructure provisioning and management.
• Experience working with satellite teams.

Benefits

In addition to a competitive salary, Graphcore offers flexible working, a generous annual leave policy, private medical insurance and health cash plan, a dental plan, pension (matched up to 5%), life assurance and income protection. We have a generous parental leave policy and an employee assistance programme (which includes health, mental wellbeing, and bereavement support). We offer a range of healthy food and snacks at our central Bristol office and have our own barista bar! We welcome people of different backgrounds and experiences; we’re committed to building an inclusive work environment that makes Graphcore a great home for everyone. We offer an equal opportunity process and understand that there are visible and invisible differences in all of us. We can provide a flexible approach to interview and encourage you to chat to us if you require any reasonable adjustments.

Sponsorship

Applicants for this position must hold the right to work in the UK. Unfortunately at this time, we are unable to provide visa sponsorship or support for visa applications.

About the Role

As the Director, Strategy & Operations - Growth, you will report to the VP, Growth and serve as the leader of Iterative Health's biological specimen collections business. This is a senior, highly autonomous role for an operator who is equally comfortable setting strategy and rolling up their sleeves to execute. You will own the go-to-market strategy, lead the full build-out of the business, and hold accountability for performance. You will also lead and develop the team that runs the day-to-day of collections operations. The ideal candidate brings a strong strategic and analytical foundation from management consulting or a high-growth startup environment, paired with the operational horsepower and ownership mindset to build something from the ground up.

Responsibilities

Go-to-Market Strategy

• Own the go-to-market strategy for Iterative Health's biological specimen collections business — defining the service offering, target customer segments, competitive positioning, and path to scale
• Define what we sell and how we sell it: Work with Business Development to scope the collections service model, establish pricing frameworks, and develop the materials and narrative needed to bring the offering to market
•  Identify and size the resourcing, infrastructure, and capability requirements needed to support the strategy and inform investment decisions

Business Build-Out

•  Lead the end-to-end build-out of the biological specimen collections business — standing up operational capabilities, and establishing the processes and infrastructure needed to execute at scale
• Own vendor contracting and relationships, including selection, negotiation, onboarding, and ongoing performance management for all collections-related vendors
• Partner with the Business Development team to develop and progress a pipeline of collections studies, supporting sponsor engagement and proposal development
• Work cross-functionally with site operations leaders to identify and onboard the right site network to support collections studies

Business Performance Ownership

• Own execution quality and sponsor satisfaction on active collections studies, serving as the senior point of escalation and ensuring trials are delivered to the highest standard
• Define and track KPIs across the business; use performance data to identify gaps, course-correct quickly, and communicate progress to senior leadership

Team Leadership

• Lead, develop, and hold accountable a team that includes pre-screeners, central Clinical Research Coordinators, and a Clinical Operations Manager — setting clear performance targets and maintaining a high-performance culture
• Train team members on workflows, protocols, and quality standards, and ensure the team has the tools, processes, and support needed to execute at pace
• Set the operational tempo for the team — running structured operations, maintaining visibility into study and team performance, and driving accountability at every level

Required Qualifications

• BS/BA or higher degree; advanced degree (MBA, MPH, or equivalent) strongly preferred
• 7+ years of experience in a strategic and operational role, with meaningful exposure to building or scaling a business — prior experience in management consulting, a high-growth startup, or a general management capacity is strongly preferred
• Experience leading cross-functional build-outs — standing up new capabilities, managing vendors, and driving commercial pipelines
• Proven people leadership experience with the ability to recruit, develop, and hold accountable a high-performing team
• Exceptional organizational and project management skills with the ability to manage multiple high-stakes workstreams simultaneously
• Strong executive presence and communication skills — able to represent the business credibly with sponsors, vendors, and senior internal stakeholders
• Comfortable operating with significant autonomy and building structure in ambiguous, fast-moving environments

Preferred Qualifications

• Experience in life sciences, clinical research, or healthcare services — particularly in biological specimen collections studies

About the Role

As the Manager, Growth, you will play a critical operational role at the center of Iterative Health's two core growth engines in Cardiology: expanding our sponsor portfolio and scaling our site network. This is a high-visibility, high-impact role for a sharp operator who thrives on process ownership, cross-functional coordination, and getting things done in a fast-moving environment. You will own the internal mechanics of business development — keeping the pipeline moving, deals progressing, and sponsors well-served — while simultaneously driving the operational build-out of new clinical research sites from contract execution through first study activation. The ideal candidate brings a strategic and operational mindset, is energized by variety, and is able to manage multiple workstreams with rigor and speed.

Responsibilities

Sponsor Growth: Business Development & Alliance Management Support

• Own the end-to-end internal business development process from initial sponsor engagement through contract execution, serving as the single internal touchpoint for new contracts
• Keep the business development pipeline organized and visible by maintaining up-to-date reporting on opportunity status, next steps, and deal progression
• Support the Director of Research Partnerships in preparing for key sponsor interactions — developing pitches and proposals, building conference materials, and ensuring the team shows up well-prepared for high-stakes meetings
• Support sponsor account meetings through internal data gathering, performance reporting, and post-meeting follow-through
• Continuously identify opportunities to streamline and improve the business development process to accelerate deal pull-through and reduce time to contract close

Site Network Growth: De Novo Site Builds 

• Partner with the Director of Clinical Research to support the end-to-end process of standing up de novo clinical research sites 
• Serve as the operational connective tissue during site stand-up, tracking progress, surfacing blockers, and ensuring all cross-functional inputs come together on schedule
• Work with the Director of Clinical Research to continuously evaluate and improve the site stand-up process — identifying inefficiencies, building out playbooks, and creating repeatable frameworks that scale as the network grows

Required Qualifications

•  BS/BA or higher degree
• 4+ years of experience in a strategic and operational role, such as management consulting, business operations, or growth/strategy at a high-growth startup
• Demonstrated ability to own and manage complex, cross-functional processes end-to-end with strong attention to detail
•  Excellent organizational skills with experience managing multiple projects and workstreams simultaneously in a fast-paced environment
• Strong communicator with the ability to synthesize information, build materials, and engage effectively with internal and external stakeholders
• Comfortable working with ambiguity and building structure where it doesn't yet exist

Preferred Qualifications

• Experience in life sciences, clinical research, or healthcare 
• Familiarity with clinical trial operations, site networks, or sponsor/CRO relationships

POS-32553

Job Description

At HubSpot, we aim to give employees the same thoughtful, high-quality experience we offer our customers, every day of their journey with us — from their first day in the office to their last. As part of the Global Facilities team, the Senior Manager, Facilities – Americas leads operations across our Americas offices, ensuring safe, reliable, and inspiring workplaces where employees and visitors can do their best work.

This role owns day-to-day facilities operations and workplace experience for our directly leased and partner-managed spaces in the Americas, manages regional vendors and building relationships, and leads a distributed team of coordinators and contingent staff. You will partner closely with Real Estate, Security, Business Technology, Workplace Experience and other key stakeholders to deliver a data-informed, employee-centric facilities strategy that scales with HubSpot’s growth.

In this role you will

Regional leadership & team management

• Lead and develop a high-performing regional facilities team (full-time, temporary, and contractor staff) across multiple Americas locations (e.g., Cambridge, San Francisco, Bogotá), providing coaching, direction, and day-to-day support.
• Set clear goals and priorities aligned to global Facilities and drive consistent operational standards across sites.
• Delegate and oversee work through our internal ticketing system, ensuring timely, high-quality responses to employee and stakeholder requests.

Facilities operations & maintenance

• Own day-to-day facilities operations for the Americas offices, including office readiness, space standards, and preventative maintenance for core building systems (HVAC, plumbing, electrical, furniture, fixtures, and equipment).
• Coordinate and resolve building and infrastructure issues (e.g., furniture failures, water heater problems, IDF/MDF spaces) in partnership with vendors, building engineers, and internal teams, from initial triage through to resolution and communication.
• Ensure that meeting rooms, cafes, collaboration spaces, and wellness areas meet high standards of quality, functionality, and cleanliness, supporting employee productivity and comfort.
• Maintain and update team workflows for all americas offices 

Vendor, building & contract management

• Serve as the primary Facilities point of contact for property managers, landlords, and key building stakeholders across the Americas region, maintaining strong relationships and clear operating rhythms.
• Source, scope, and manage vendors for services such as janitorial, carpet and floor care, furniture, blinds, mechanical/plumbing, and specialty trades — including obtaining quotes, validating scope, scheduling work, and monitoring performance.
• Partner with Procurement and Finance on purchase requests, POs, and cost optimization (e.g., scheduling to avoid overtime labor where possible, aligning work with building access windows).

Workplace experience & front-of-house support

• Ensure a consistently excellent front-of-house and visitor experience in Americas offices, including reception standards, wayfinding, and event support in collaboration with on-site teams.
• Oversee coordination of mail, shipping/receiving, and logistics, including high-value and international shipments in partnership with Business Technology and external carriers.
• Support office events, intentional gatherings, and other on-site activities by ensuring facilities, services, and vendors are aligned to program needs.
• Manage large office moves, terminations including desk assignments. 
• Maintain and update floorplans when changes happen or new offices open, this includes updating the CAFM system to ensure floorplans are up to date.
• Review and coordinate parking assignments notifying the appropriate individuals to provide access.

Health, safety, security & emergency readiness

• Act as a key regional contact for facilities-related emergencies, coordinating with Security, IT, and local building teams to respond to incidents across Americas sites (e.g., IDF/MDF issues, building systems failures, safety concerns).
• Maintain and contribute to emergency contact lists, playbooks, and on-site procedures for multiple locations, ensuring information is current, accurate, and visible to the right stakeholders.
• Partnering with Security and local offices leads to support physical security practices (e.g., access control, cameras, vendor access) and align with HubSpot’s safety expectations.

Projects, space changes & cross-functional collaboration

• Lead and support facilities components of office projects in the Americas (e.g., reconfigurations, furniture changes, programmatic improvements, capital projects) in partnership with Real Estate, Construction partners, BT, and local stakeholders.
• Collaborate closely with global Facilities and Real Estate peers to ensure alignment on standards, data, and reporting, and to share best practices across regions.
• Use ticketing and space data to identify trends, propose improvements, and inform prioritization and investment decisions across the Americas portfolio.

Documentation, communication & knowledge sharing

• Maintain and enhance Facilities documentation for Americas offices, including wiki content, emergency information, operating procedures, and office-specific guides.
• Communicate proactively with employees, partners, and leadership about facilities work, impacts, and timelines, ensuring transparency and building trust.

Our ideal candidate

• Has 7+ years of experience in facilities management, workplace operations, property management, or a related field, including multi-site responsibility and complex office environments.
• Has at least 5+ Years of people management experience, leading and developing distributed teams and working with contingent staff and vendors.
• Demonstrates strong vendor and stakeholder management skills and is comfortable working directly with landlords, property managers, and specialty contractors to solve operational issues.
• Is highly organized, able to prioritize across multiple offices, manage competing deadlines, and stay calm and effective in time-sensitive or emergency situations.
• Communicates clearly and empathetically in writing and in person, tailoring their style for employees, senior leaders, vendors, and building teams.
• Is data-informed and comfortable using ticketing systems and basic reporting to spot patterns, drive improvements, and measure the impact of facilities programs.
• Brings a strong customer-first mentality, with a passion for creating inclusive, welcoming, and accessible spaces for all employees and visitors.
• Aligns with HubSpot’s HEART values and is eager to collaborate across regions and functions to help our global team thrive.

Knowledge of Health & Safety practices, building systems, environmental sustainability, and physical security is a strong plus. Additional languages are a plus.

Diversity & inclusion

Confidence can sometimes hold people back from applying for a role, but there’s no such thing as a “perfect” candidate. HubSpot is a place where everyone can grow, so however you identify and whatever background you bring, please apply if this role excites you and you’re eager to support our teams across the Americas every day.

About HubSpot

HubSpot (NYSE: HUBS) is a leading customer relationship management (CRM) platform that provides software and support to help businesses grow better. We build marketing, sales, service, and website management products that start free and scale to meet our customers’ needs at any stage of growth. We’re also building a company culture that empowers people to do their best work and supports a diverse, inclusive workplace.

Thanks to the work of every employee globally, HubSpot has been recognized for our culture and as a great place to work by Glassdoor, Great Place to Work, Comparably, Fortune, Entrepreneur, and more. Today, thousands of employees work across the globe in HubSpot offices and remotely.

By submitting an application, candidates agree that HubSpot may collect their personal data for recruiting, global organization planning, and related purposes, as outlined in HubSpot’s Privacy Notice.

The Senior Employer Branding Manager is responsible for developing and executing strategies that highlight our culture, values, and employee experience to attract top talent and engage current employees. This role combines storytelling, content creation, video and photography production, and data-driven program design to position CMT as an employer of choice. You’ll own the employee-facing content that shapes how it feels to work here — from the company newsletter to the videos and photos that show the real humans behind the mission — and you’ll support the in-person events that bring our culture to life. This role reports to the Head of Branding and Internal Communications.

Responsibilities:

• Develop and lead the execution of a comprehensive employer branding strategy aligned with CMT’s culture and talent goals
• Own the company newsletter end-to-end — editorial calendar, writing, editing, and measurement — making it something employees actually open and read
• Craft compelling content across written, social, video, and photo formats (social posts, career site updates, blogs, internal comms, employee spotlights, team stories, recruiting videos, event recaps) that highlights our mission, values, and employee experience, ensuring consistency across all touchpoints
• Build and run crowdsourced content programs that get people across the company creating — employee creator programs, content challenges, employee advocacy — equipping teammates with templates, prompts, and light coaching so the stories come from the people living them
• Partner with People Operations, Marketing, and Leadership to design campaigns that engage potential candidates and inspire current employees
• Analyze eNPS, engagement survey data, and other employee sentiment metrics to identify what’s working and where to invest — then design programs that move the numbers
• Monitor and manage CMT’s employer reputation across online sources where candidates and employees rate us — Glassdoor, LinkedIn, Google, Indeed, Comparably, Built In, and emerging platforms — tracking sentiment, responding to reviews, surfacing themes for leadership, and building proactive engagement strategies
• Manage external partners when needed — videographers, photographers, freelance writers, designers, and agencies — keeping work on brand, on schedule, and on budget
• Provide general support for in-person employee and recruiting events — offsites, all-hands, career fairs, campus recruiting, ERG events — from planning through on-site execution
• Analyze campaign performance and employer brand metrics to refine strategies and ensure alignment with organizational objectives
• Lead projects to amplify our presence in the job market, including developing employee advocacy programs, applying for workplace awards, and partnering with industry organizations
• Work across teams to identify opportunities for alignment between employer branding efforts and broader brand and content goals
• Stay updated on employer branding trends, tools, and technologies to keep strategies fresh and competitive
• Complete any additional tasks as they arise

Qualifications:

• Bachelor’s degree or equivalent years of experience and/or certification in Marketing, Communications, or a related field
• 5+ years of experience in employer branding, internal communications, talent marketing, content creation, or a related discipline
• Proven ability to develop and execute strategic branding initiatives that deliver measurable results
• Exceptional storytelling skills, with experience crafting engaging content across written, social, video, and photo formats
• Fluency with video editing — you can take raw footage and turn it into something worth watching, using tools like Adobe Premiere, Final Cut, CapCut, or similar
• Comfortable behind a camera — shooting and editing photography for newsletters, social, the career site, and on-site event coverage
• Experience building programs that get other people creating — employee advocacy, creator programs, crowdsourced content — and the coaching instincts to make non-marketers comfortable contributing
• Analytical mindset — comfortable working with eNPS, engagement survey data, and campaign performance metrics, and translating what you find into programs that actually move the numbers
• Experience managing external creative partners (videographers, photographers, freelancers, agencies) on brand, on schedule, and on budget
• Strong project management skills, with the ability to manage multiple priorities and stakeholders effectively
• Comfortable providing hands-on support for in-person events — logistics, setup, run-of-show, on-site execution
• Excellent interpersonal skills, with a demonstrated ability to work collaboratively across teams and departments
• Proficiency in social media platforms, content management systems, and employer branding tools (LinkedIn Talent Brand / Careers Pages / Life Tab, Canva, or similar)
• A solution-oriented mindset with a proactive approach to problem-solving
• Writing and content samples / portfolio required with application — please include examples of written content, video, and any employee-facing programs you’ve built

Nice to Haves:

• Experience with motion graphics, animation, or more advanced video production
• Experience with workplace awards submissions (Built In, Glassdoor, Great Place to Work, etc.)
• Familiarity with HR systems and engagement platforms (Greenhouse, Culture Amp, Lattice, or similar)

Compensation and Benefits:

• Fair and competitive salary based on skills and experience, and annual performance bonus
• Equity may be awarded in the form of Restricted Stock Units (RSUs)
• Medical, Dental, Vision and Life Insurance, matching 401k, short-term & long-term disability and parental leave
• Unlimited Paid Time Off including vacation, sick days & public holidays
• Flexible scheduling and work from home policy depending on role and responsibilities

Additional Perks:

• Work on a mission with real impact: crashes prevented, injuries avoided, lives protected around the world
• Join an industry leader — 65 million drivers protected, powering 140+ programs across 25 countries
• Be part of the team inventing the future of mobility and road safety
• Move fast, own outcomes, do work that matters
• High ownership, small teams, and direct access to leadership — no layers between your work and its impact
• Unlimited PTO, flexible scheduling, competitive salary, annual performance bonus, RSUs, and full benefits including medical, dental, vision, and 401k match
• Summer Fridays
• Comprehensive wellness, education, and employee assistance programs

About Cambridge Mobile Telematics:

Cambridge Mobile Telematics (CMT) is the world’s largest telematics and AI company for safer mobility. Its mission is to make the world’s roads and drivers safer. The company’s AI-driven platform, DriveWell Fusion®, proactively identifies and reduces driving risk, leading to fewer crashes and injuries. To date, CMT’s technology has helped prevent over 126,000 crashes worldwide. CMT enables partners to measure risk, detect crashes, provide life-saving assistance, and streamline claims. Headquartered in Cambridge, MA, CMT operates globally with offices in Budapest, Hungary; Chennai, India; Seattle, Washington; Tokyo, Japan; and Zagreb, Croatia. Learn more at www.cmt.ai.

The Role:

Reporting to the Head of Contracts, the Senior Manager, Contracts - Clinical will serve as the primary contracts professional working closely with the Clinical function, particularly Clinical Operations. This is a hands-on, high-volume role responsible for the full lifecycle of clinical site agreements and ancillary clinical contracts across Nuvalent’s global study portfolio, currently spanning four concurrent studies including a Phase 3 randomized controlled trial.

The ideal candidate has deep experience in global clinical site contracting at a sponsor company or CRO, is comfortable operating with significant autonomy, and has the judgment to know when to resolve an issue independently and when to escalate. This role works directly alongside a peer team of Senior Contracts Managers within a contracts department that is growing alongside Nuvalent’s pipeline.

Responsibilities:

Clinical Site & Study Agreements

• Draft, review, negotiate, and execute Clinical Trial Agreements (CTAs) with academic medical centers, community research sites, and international investigator sites across global markets.
• Manage the full contract lifecycle from initial draft through execution, amendment, and close-out across a high-volume, multi-study portfolio.
• Coordinate Informed Consent Form (ICF) review as needed in connection with site-level contracting.
• Negotiate and process Work Orders (WOs) and Change Orders (COs) in coordination with Clinical Operations and relevant CRO or vendor counterparties.
• Serve as the primary contracts point of contact for site administrators, legal counsel, and CRO contract teams, maintaining productive counterparty relationships through complex negotiations.

Ancillary Clinical Contracts

• Draft, review, and negotiate Confidential Disclosure Agreements (CDAs) and Non-Disclosure Agreements (NDAs) for clinical partnerships and site-level engagements.
• Manage consulting agreements for clinical investigators, key opinion leaders, and clinical consultants engaged by Clinical and Clinical Operations, with appropriate escalation of HCP engagements for compliance review.
• Support statements of work and related agreements for Clinical and Clinical Operations vendors.

Contract Operations & Process

• Maintain accurate, complete, and timely contract records in Nuvalent’s contract management system (Agiloft), including status updates, executed document storage, and obligation tracking.
• Apply and enforce departmental file naming conventions, version control standards, and repository management protocols.
• Provide timely contract status visibility to Clinical and Clinical Operations business owners and serve as a reliable point of contact for internal stakeholders throughout the contract lifecycle.
• Identify issues requiring escalation and engage appropriate internal resources — including Legal, QA, Regulatory, Clinical Operations, Finance, IT, and Compliance — or external resources including CRO counterparties, outside counsel, or the Data Privacy Officer (DPO).
• Contribute to negotiation playbooks, standard fallback positions, and contract templates for clinical contract types.
• Coordinate with Legal and the DPO on data privacy provisions in clinical agreements, including GDPR data processing terms for EU and international site agreements.
• Utilize AI-assisted contract review tools as integrated into departmental workflow in accordance with established Nuvalent guidance.
• Lead or co-lead department initiatives to support an expanding organization.

Competencies Include:

• Detail and process oriented, with strong organizational skills and the ability to manage a high-volume, multi-study contract portfolio across competing deadlines and shifting priorities.
• Strong negotiation, problem solving, and communication skills, with the ability to hold a position, find common ground, and close without unnecessary escalation.
• Flexibility with changing priorities and ability to think critically under pressure.
• Ability to work in a collaborative environment and build effective working relationships across the organization, including with external counterparties such as site administrators, CRO contract teams, and outside counsel.
• Sound judgment in recognizing when to resolve independently and when to bring in the right internal or external resources.
• Able to thrive in a remote/virtual environment.

Qualifications:

• Minimum of 7 years of contracts experience in the biopharmaceutical or clinical research industry, with at least 4 years focused on vendor agreements, clinical site agreements, investigator agreements, or study start-up contracting; sponsor-side experience preferred, CRO-side experience considered.
• Demonstrated experience negotiating CTAs, WOs, COs, CDAs, and HCP consulting agreements at volume across multiple concurrent studies.
• Direct experience contracting with international clinical sites and working knowledge of applicable legal and regulatory requirements including GDPR data processing considerations.
• Working knowledge of GCP, ICH guidelines, and FDA regulations governing clinical research and their practical implications for contract terms.
• Familiarity with IRB processes and their intersection with site-level contracting.
• Proficiency with contract lifecycle management systems; experience with Agiloft, Ironclad, DocuSign CLM, or comparable platforms required. Agiloft experience a plus; training will be provided.
• Oncology experience preferred; relevant experience from adjacent therapeutic areas will be considered.
• Familiarity with AI-assisted contract review tools a plus.
• Bachelor’s degree or equivalent experience required.

Additional Information:

Nuvalent is committed to fair and equitable compensation practices, aiming to provide employees with competitive total rewards packages.

The targeted salary range reflects what Nuvalent reasonably and in good faith expects to offer for this position at the time of posting, but the final salary determination may be within or outside this range based on various factors, including, but not limited to, experience, skills, education, and market factors.  The range will be reviewed regularly and is subject to change.

Nuvalent also offers a comprehensive benefit package to support our employees at each stage of their career, financial, health, and well-being journey, including medical, dental, and vision insurance, 401(k) retirement savings plan, generous paid time off (including a summer and winter company shutdown), and much more.

Your Impact at LILA

Lila Sciences is seeking a detail-oriented and process-driven HR Generalist (Contract) to join our HR Operations team. This role will serve as the execution backbone of our HR Operations function. The HR Generalist will handle the day-to-day administration of the employee lifecycle, systems management, benefits support, and cross-functional HR tasks. This is a high-execution role best suited for someone who takes pride in doing administrative work accurately and efficiently, thrives on process ownership, and is energized by bringing order and consistency to a growing organization.

What You'll Be Building

Employee Lifecycle, Onboarding & Offboarding

• Execute end-to-end pre-boarding and onboarding processes, including coordination of IT intake, systems access setup, and employee introduction materials
• Identify and implement improvements to pre-boarding workflows to increase consistency and reduce manual effort
• Support offboarding administration, including exit paperwork and required system updates
• Process administrative HR actions across the employee lifecycle: new hires, transfers, internal role changes, manager changes, and terminations
• Generate employment letters (transfer, termination, etc.) and manage signature request workflows
• Maintain and organize employee documentation in accordance with compliance requirements

Immigration & Benefits Administration

• Manage immigration paperwork and coordinate with external counsel or vendors on active cases under HR Operations Manager guidance
• Administer benefits tasks that cannot be automated, including enrollment support and data entry
• Provide leave administration support as needed, in coordination with HRBPs

HR Inbox & Employee Support

• Manage the HR team inbox: triage, respond to, and route inquiries related to onboarding/offboarding, immigration, benefits, and company policies
• Serve as a reliable first point of contact for employee and manager HR questions, ensuring timely and accurate responses, and escalating complex cases appropriately

Process & Compliance

• Own the I-9 compliance process end-to-end: complete Section 2 verification for all new hires, manage re-verification for expiring work authorization documents, maintain organized and audit-ready I-9 records, and coordinate E-Verify submissions where applicable
• Collaborate with HR Operations to document, standardize, and improve HR workflows and procedures

What You’ll Need to Succeed

• 1–3+ years of HR experience with a focus on HR operations, administration, or HR coordination
• Hands-on experience with HRIS platforms; HiBob and/or ADP experience is a plus
• Strong attention to detail and a track record of accurate, high-volume administrative work
• Comfortable managing multiple competing priorities with minimal supervision
• Clear and professional communicator (written and verbal)
• Ability to handle sensitive, confidential HR information with discretion
• Demonstrated commitment to process improvement and operational consistency
• Local to the Cambridge, MA area; able to work hybrid (averaging ~3 days/week onsite based on need)

Bonus Points For

• Experience with ATS platforms (e.g., Greenhouse)
• Direct experience administering the I-9 process
• Experience with process documentation and process flow documents
• Familiarity with immigration processes and vendor coordination
• Experience supporting benefits administration or leave management
• Comfort with ambiguity in a fast-paced, evolving environment

The Opportunity

We are seeking an experienced Associate Director, Contracts to refine and scale our contracting operations and review as we prepare for a potential drug launch. This role will own the full contract lifecycle process—from intake and template selection through, execution and post‑execution management, including negotiating certain agreements independently. This is a highly visible, customer‑service‑oriented role that will serve as the internal subject‑matter expert and trainer for Amylyx’s contract lifecycle management system (CLMS). The ideal candidate will have a strong background in contract management and negotiation within the life sciences, biotech, or pharmaceutical industry and thrive in a fast‑moving, evolving environment.

Responsibilities

Contract Management & Operations

• Optimize and implement contracting processes and best practices, ensuring efficient workflows, compliance, and continuity across teams.
• Manage end-to-end contract lifecycle for a broad set of contracts, e.g. services, confidentiality, research collaborations, and other commercial or operational contracts.
• Maintain the contract management system and repository, including metadata accuracy, key date tracking, renewal management, obligation monitoring, tags, parties and reporting.
• Partner closely with internal stakeholders (Legal, Compliance, Finance, Procurement, Clinical, Commercial, and other business partners) to ensure contract terms align with business and compliance needs.
• Develop, update, and maintain contract templates and playbooks in partnership with Legal advisors.
• Develop and maintain CLMS training materials and provide new hire and refresher training sessions as well as ad hoc support.
• Establish and track contracting KPIs, dashboards, and metrics to provide visibility into system performance and contracting volume.
• Partner with the IT Administrator to drive continuous contracting process improvements, including identifying opportunities to streamline workflows through automation and the use of Artificial Intelligence tools.

Contract Review & Negotiation

• Prepare and negotiate agreements independently or escalate non-standard terms to manager with potential positions.
• Develop and maintain contract templates and playbooks.

Required Qualifications

• Bachelor’s degree required; JD or Paralegal Certification preferred.
• 8+years of experience in contract management and with CLM system(s); experience independently negotiating contracts.
• Strong ability to prioritize, independently manage workload, and meet deadlines in a dynamic environment.
• Exceptional written, verbal, and interpersonal communication skills with a focus on customer service and excellent attention to detail.
• Proven ability to work with cross-functional teams and build strong internal relationships.
• Aligned with a patient‑focused mission and able to uphold the highest standards of integrity.

Preferred Qualifications

• Experience with LinkSquares contract lifecycle management system.
• Demonstrated experience applying AI tools to contract review or process optimization.
• Industry experience in biotech, pharma, or life sciences.

Work Location and Conditions

• At Amylyx, we proudly support remote work opportunities within the United States. However, due to business considerations candidates must be able to attend meetings at our office in Cambridge, MA on a regular basis.  Preference will be given to candidates who reside in the New England region and can be in person on an as needed basis.
• When working remotely, you must have access to a work setting which enables meeting all requirements of the role (including privacy, reliable internet access, phone, ability to video conference, etc.) at your remote location.

The Role:

Reporting to the Director, Global Regulatory Affairs, the Senior Manager, Regulatory Affairs role will integrate regulatory strategic development, submission management expertise, and hands-on execution to support the IND/CTA stage of development through NDA/MAA.

The Senior Manager, Regulatory Affairs will contribute to the development and implementation of regulatory strategy as a member of the global regulatory affairs function and clinical study team(s). This role will manage the process for preparation, submission and internal review and approval of regulatory documents, including providing technical regulatory input for global documents to streamline development.

The Senior Manager, Regulatory Affairs must be kept current, innovative, and compliant with the constant changing Health Authority requirements to facilitate regulatory processes and compliance maintenance from IND/CTAs through NDA/MAA. 

Responsibilities:

• Participates as a regulatory representative for Clinical Study Team (CST) on development programs assigned working closely with product development team (PDT) lead to develop the global regulatory strategy; work closely with regulatory operations and program management to track timelines and ensure deliverables are achieved
• As part of the regulatory clinical study team, you will support preparation, review, compilation, and execution of submissions for regulatory agencies for US and ROW (e.g., IND/CTAs, NDA/MAA, DSURs, Amendments, and Responses to Regulatory Agency Requests for Information, etc.)
• Provide regulatory guidance and support to senior regulatory affairs members on various projects, as needed, to further development programs (pediatric development planning, regulatory interactions, NDA planning)
• Ensure collaboration with and coordination of cross-functional project teams for timely execution of regulatory submissions, maintaining compliance with global regulatory standards and commitments, and providing regulatory guidance and oversight
• Support regulatory operations during the regulatory submissions handoff process, as the primary point of contact for external publishing vendors, ensuring submission packages are accurate, formatted correctly, and validated.
• Maintain the regulatory information system and ensure proper archiving, searchability, and accessibility of regulatory content including correspondence with regulatory agencies
• Manage regulatory submission processes, develop and maintain regulatory tracking tools and infrastructure, as assigned Conduct regulatory intelligence and competitive intelligence and summarize key impacts to global strategy development teams, as appropriate
• Ensure compliance with internal SOPs, regulations and applicable laws. Drafts and reviews Regulatory Affairs SOPs and work instructions and provides Regulatory feedback on other departmental SOPs, where required

Competencies Include:

• Excellent attention to detail and ability to complete efficient and detailed technical data review
• Excellent organization, communication, and multi-tasking skills
• Exceptional interpersonal skills and experience contributing to productive teams and fostering cross functional relationships
• Strong desire to contribute as a member of an engaged and collaborative cross-functional project development team

 Qualifications:

• 6-8 years of experience in Regulatory Affairs or combination of education and direct experience.
• Bachelor or advanced degree in a scientific field or equivalent work experience is required.  Master’s degree a plus.
• Proven experience in evaluation, preparation and compilation of quality dossiers in all required formats and/or experience in regulatory processes.
• Solid understanding of the e-CTD specifications for electronic submissions.
• Knowledge and practical understanding of ICH Guidelines regarding GMP/GCP, ICH Guidelines for CTD/eCTD and CDER requirements for the drug approval process.
• Previous participation in preparing and/or leading regulatory submissions (IND, CTA, NDA, etc.). Experience with preparing meeting packages is a plus.
• Experience in interpretation of regulations, guidelines and precedents related to drug development in the US and EU.
• Strong understanding of regulatory eCTD structure and clinical trial conduct and design
• Proficiency with electronic submission publishing software and document management information systems (i.e., docuBridge, Veeva Vault RIM)
• Ability to plan, prioritize and contribute to work and projects in a systematic and efficient manner with emphasis on streamlining processes

Additional Information:

Nuvalent is committed to fair and equitable compensation practices, aiming to provide employees with competitive total rewards packages.

The targeted salary range reflects what Nuvalent reasonably and in good faith expects to offer for this position at the time of posting, but the final salary determination may be within or outside this range based on various factors, including, but not limited to, experience, skills, education, and market factors.  The range will be reviewed regularly and is subject to change.

Nuvalent also offers a comprehensive benefit package to support our employees at each stage of their career, financial, health, and well-being journey, including medical, dental, and vision insurance, 401(k) retirement savings plan, generous paid time off (including a summer and winter company shutdown), and much more.

Director, Finance & Administration

Harvard Hillel

Location: On Site, Harvard Hillel  |  Cambridge, MA

Employment Status: Exempt salaried staff member

Reporting: Jason Rubenstein, Executive Director 

Salary Range: $100,000 - $120,000

Role Overview

The mission of Harvard Hillel is to be a Jewish home, both physical and virtual, on the Harvard University campus. Harvard Hillel welcomes all students to experience the variety of Jewish identity, tradition, practice, values, culture, and community and to inspire and enable connections on campus and beyond. Harvard Hillel students find meaningful connections and friendship while engaging in unique opportunities to make Jewish thought and culture integral in the life of the University.

The Director, Finance & Administration (Director) reports to the Harvard Hillel executive director who has been in the role less than two years. As a team, you will engage effectively with internal and external constituent groups around operational excellence at Harvard Hillel. The Director will move easily between strategic decision-making, governance requirements, and the everyday tactical coordination and planning that brings operational priorities to fruition. The Director serves as an empathetic and collaborative leader and coach, where operational excellence and a positive engagement around organizational culture is as important as rigorous monitoring of systems and process.

The Director’s role will ensure effective and consistent financial integrity and compliance of this 501(c)(3) institution. Working closely with the executive director, chief of staff, and other stakeholders, the Director will oversee the planning, coordination, and tracking of institutional annual goals against budget. The Director will serve as a trusted advisor and thought partner to the executive director and staff on organizational priorities, strategic goal setting, and effective project coordination in relation to designing and meeting budget goals.

Key to the success of the Director’s role is to add capacity to the executive director to support the transformation of the institution and its future. In year one, the Director will actively engage with colleagues and outsourced providers to modernize financial budgeting systems, tracking and reporting. Over time, a successful Director in this role will help reshape Harvard Hillel—its building and its operations, to move the organization forward.

Anticipated accountabilities are outlined below. The Director will be expected to actively surface and collaboratively projects to design and address anomalies to ensure work moves forward effectively and efficiently.

What You’ll Do

Annual Planning & Financial Management

• Accounting, Banking, Benefits, Insurances, Payroll: accountability for ensuring an annual cycle, with relevant systems, tracking, and reporting designed and implemented to record and reflect on the overall fiscal health of the organization.
  • Lead annual budget cycle: engaging with budget holders and other colleagues to establish and coordinate an effective budget planning process and reporting tools to support budget holders’ ability to manage and track their budgets and cashflow. At minimum, monthly and quarterly budget reviews, cash flow management and reporting, and ad-hoc tracking and issue resolution as needed. Ensure organizational priorities are visible, clear, and actionable in relation to budget monitoring and tracking. Lead communications in relation to annual budget cycle process and the obligations of contributors. Serve as a trusted colleague and coach around budget management, accountability, and tracking in relation to finance and budgets.
  • Lead annual cycle of audited financial statements and filings: engage with external providers to oversee and actively manage the timely scheduling and delivery of an annual audit; delivery of a 990, and to meet an annual schedule of filing obligations.
  • Annual Insurances: engage with a broker and others to manage insurance obligations for this 501(c)(3) organization.
  • Departmental planning and analyses: In year one, redesign financial planning, budgeting, tracking, and reporting systems, with analysis tools that are right-sized for the institution, in preparation for a capital project to renovate the historic Rosovsky building and to support the institution's journey to scale.

Board of Directors Operations

• Working closely with the chief of staff and executive director, and Board committees, plan and coordinate audit, finance, and risk related committees and reporting to meet timely Board reporting and meetings. Serve as the staff liaison for finance, audit, and risk related committee meetings and discussions.
• Support committee development, structures, and governance principles and processes to ensure the organization’s ByLaws support and drive compliance and governance decision-making in relation to financial risk.

Fiscal Sponsorships Management

• In close coordination with the Director of Programs and others, actively manage student-led initiatives related to financial controls, guidance on policy, procurement, and expenditures and timely payments of events for student-led projects.

Policy Design and Management

• Actively review and manage organizational policies in relation to both risk management and business continuity, balancing the organization’s values and core programming, to facilitate a smooth-running institution in service of students and other stakeholders.
• Schedule routine policy review cycles to ensure the organization is up to date with best practices and technologies to function with operational excellence.

Human Resources

• Work closely with payroll providers and benefits brokers to manage an annual benefits cycle of enrollments and benefits assessments, actively engaging and communicating with staff through a benefits review cycle.
• Actively engage with the chief of staff to design and implement an annual cycle of health and safety protocols specific to this institution. Working closely with the chief of staff and executive director, actively track and monitor engagement in mandatory trainings for Boston, MA.
• Work in close partnership as needed on staff disciplinary activities, including investigations, performance management support, hiring and termination, holding personnel records and record keeping for related human resources materials.

Facilities

• Oversee the planning of budgets and coordination support needs for buildings owned or rented by Harvard Hillel.
• Oversee the health and safety, security, and business continuity planning around onsite activities, in close partnership with the manager of facilities and operations and the executive director.
• Oversee onsite programmatic activities and events in close liaison with the Director of Program and Facilities Manager, ensuring smooth running of event scheduling, planning, and logistics.
• Oversee management and coordination of facilities technologies serve onsite programming through facilities.
• Identify and manage cost-savings opportunities for services provided by Harvard University and others.

Minimum Qualifications

• 10+ years of experience as a CFO with an Operations portfolio, Finance & Operations Manager, or similar role in a nonprofit or community engagement organization.
• High comfort in Microsoft Office tools, QBO, Bill.com, other financial management platforms.
• Bachelor’s Degree or equivalent.

Knowledge, Skills and Abilities 

• 8+ years of progressive experience in nonprofit or mission-driven leadership roles.
• Commitment to the organization’s mission and respectful of Jewish values.
• Demonstrated success in strategic planning and execution, operational systems and tracking, and Board governance. People-center systems thinker, with strong success operationalizing strategies into trackable, measurable action plans.
• Strong financial, project management, and institutional administration skills.
• Exceptional written, verbal, and interpersonal skills.
• Highly effective manager of people, projects, and budgets.
• Adaptable, sound judgment, diplomatic, and respectful of holding sensitive information.
• Ability to successfully balance high emotional intelligence with result-driven project management and serving as an empathetic culture carrier who models collaborative leadership and teamwork.
• Open and willing to engage in conversations about religion, and to learn about Judaism and Israel in a way that inspires stakeholders to invest in our work.
• Highly collaborative problem-solver with curiosity to engage across teams both inside and outside of Hillel to successfully manage competing priorities.
• A self-starter, adept at project management tools and practices, time-management and effective communications both verbally and in writing.
• Highly comfort working effectively both independently and in teams to meet goals and deadlines.

Benefits

• A comprehensive benefits package, including health insurance, retirement plan, Life, AD&D and Long-Term Disability (LTD) insurances, Flexible Spending accounts, generous vacation/sick time, and parental leave.
• A unique opportunity to develop and promote a vibrant, pluralistic Jewish community at Harvard Hillel.

Harvard Hillel is affiliated with Hillel International. Hillel International enriches the lives of Jewish students so they may enrich the Jewish people and the world, and envisions a world where every student is inspired to make an enduring commitment to Jewish life, learning and Israel.

AEG Worldwide is the world’s leading sports and live entertainment company with operations in the following business segments:

• AEG Presents, which is one of the largest live music companies in the world dedicated to live contemporary music performances, including producing and promoting global and regional concert tours, music events and world-renowned festivals
• AEG Sports, which is the world’s largest operator of sports franchises and high-profile sporting events
• AEG Global Partnerships, which supports each of AEG’s divisions through worldwide sales and servicing of sponsorships including naming rights, premium seating and other strategic partnerships
• AEG Real Estate, which develops major sports and entertainment districts worldwide

With offices on five continents, the company uses its global network of venues, portfolio of powerful sports and music brands, ticketing and content distribution platforms and its integrated entertainment districts to deliver the most creative and innovative live sports and entertainment experiences that inspire athletes, teams, artists and fans.

SECURITY STAFF

• SECURITY OFFICER
• SECURITY SUPERVISOR
• SECURITY MANAGER
• FIRE SAFETY OFFICER
  
  

1. SECURITY OFFICER

SUMMARY

The Security Officer will maintain the safety of all employees, guests and clients at shows, events, festivals, tours, one-offs and venues through constant patrol, observation and documentation.  This position will be first point of contact for all security related issues and will control the diffusion of incidents at the event. The Security Officer will also assist with customer service requests. 

PRIMARY RESPONSIBILITIES

• Monitor assigned area of venue on foot.  Observe, report, and control ongoing activity keeping track of unusual occurrences.  Assist with the ejection or control of unruly, disruptive, intoxicated guests. 
• Monitor entry and access point for the venue.  Ensure all guests and employees have appropriate access to be in each specific area. 
• Escort artists, VIPs, guests and employees to protect and prevent unwanted attention, disruption, incident or injury. 
• Respond immediately to fire control center to locate, acknowledge and silence alarm.  Check signal area, report and reset alarm.  Enact fire safety/evacuations when necessary. 
• Respond, observe and document all medical situations and request EMT/medical personnel.  Assist with minor first aid situations.  Coordinate transportation for friends and family of afflicted when necessary. 
• Assist with all customer service needs before, during and after each show, including: directions, instructions, information, escorts and medical. 
• Screen and confirm all employees, vendors, delivery personnel, guests and artists entering venue to ensure appropriate access.  Review and verity documentation to ensure validity. 
• Log all activity, movement and repairs in appropriate log ensuring all incidents are accurately documented.   

QUALIFICATIONS

• A minimum education level of: High School Diploma or its equivalency  
• 1 – 2 years of related work experience 
• Strong interpersonal, verbal and written communication skills. 
• Expert organizational, leadership and time management skills.   
• Ability to qualify and be issued a security officer license. 
• Ability to obtain and maintain a Guard Card 
• CPR and AED certification  
• Knowledge of rules and regulations with good understanding of right and wrong 
• Must be able to stand for long periods of time  
• Must be able to work long hours including nights, weekends and some holidays 
• Knowledge of music industry and live events preferred 

2. SECURITY SUPERVISOR

SUMMARY

The Security Supervisor will protect the safety and security of AEG Presents’ guests, employees, clients and assets.  This position will monitor and record activity made on the venue security cameras and by guests, employees, and clients at the event. The Security Supervisor will ensure that any potential threat is diffused and that safety is maintained for all parties at the event.

PRIMARY RESPONSIBILITIES

• Monitor and record activity on venue security cameras. 
• Ensure that all cameras are working properly and unobstructed. 
• Monitor guests, visitors and workers to anticipate any potential threat to AEG Presents property, employees, guests or clients. 
• Maintain Daily Activity Log with information reported by security team members. 
• Record equipment repairs, guest incidents and near miss situations.  
• Actively patrol building to ensure venue doors are secured and there aren’t any pressing security issues.
• Prepare and maintain daily log sheets for team radios and key cards for team.   
• Prepare non-show deployment. 
• Obtain pertinent information from previous shift to anticipate needs of current shift. 
• Maintain fire control system to ensure system is in proper working order. 
• Activate system during shows/events and inactive when venue is dark.   
• Monitor housekeeping activity, unlock and open doors, and provide escorts for housekeeping when necessary. 
• Issue daily credentials for employees, workers and visitors when necessary. 
• Maintain visitors log, ensuring guests sign in and out.   
• May be responsible for assisting with group tours, delivery check in and delivery logged.    
• Oversee and manage staff including, hiring, scheduling, timecard management and terminations.  

QUALIFICATIONS

• A minimum education level of: High School Diploma or its equivalency (Bachelor of Arts/Sciences Degree Preferred)   
• 3- 5 years of related work experience 
• Law enforcement or security experience 
• Strong interpersonal, verbal and written communication skills 
• Expert organizational, leadership and time management skills  
• Must be able to stand for long periods of time 
• Must be able to work long hours including nights, weekends and some holidays 
• Ability to qualify and be issued a security officer license 
• Knowledgeable of OSHA/ADA laws and regulations
• Management experience 

3. SECURITY MANAGER

SUMMARY

The Manager Security will ensure the safety of all persons at the event at any given time.  This individual will also provide proper staff training on a variety of different hazards or situations that can occur during any event.  They will be in charge of recruiting, scheduling, overseeing and evaluating staff and making sure they are up to date on policies and procedures.  They will also oversee the maintenance of records, make sure all credentials are up to date and work with other agencies to set up training.   

PRIMARY RESPONSIBILITIES

• Interact with all departments to make sure everyone is aware of all safety/security protocols.    
• Train new and current employees on risk management policies and procedures for festivals, shows, venues and one-offs. 
• Responsible for various types of onsite incidents. 
• Manage incidents according to proper policies and procedures, create incident reports and file accordingly. (e.g., medical emergencies and disruptive guests).
• Maintain proper degrees of credentialing throughout the festivals, shows, venues and one-offs.   
• Implementing ABI for security staffing, creating deployments for security companies, managing the ABI security audit team, perform security audits at events with significant deployments, supervising team and assisting with security planning at festivals, shows, venues and one-offs. 
• Oversee and manage staff including, hiring, scheduling, timecard management and terminations.  

QUALIFICATIONS

• A minimum education level of: High School Diploma or its equivalency (Bachelor of Arts/Sciences Degree Preferred)  
• 5 years of related work experience 
• Law enforcement or security experience 
• Exceptional computer skills with proficiency in Microsoft Excel and Adobe software 
• Strong interpersonal, verbal and written communication skills 
• Expert organizational, leadership and time management skills 
• Knowledgeable of OSHA/ADA laws and regulations 
• Strong management or leadership background 
• Ability to qualify and be issued a security officer license 
• Demonstrated success in team building 
• Management experience 
• Understanding of Guard Cards 

4. FIRE SAFETY OFFICER

SUMMARY

The Fire Safety Officer will be responsible for facilitating compliance and helping minimize hazardous situations. Additionally, this position will conduct regular inspections to ensure safety procedures are taken. 

PRIMARY RESPONSIBILITIES

• Monitor the fire panel during events in case issues arise and ensure the panel is reset after all events. 
• Oversee installations, maintenance, etc. Conduct regular inspections and be on-site for all events to ensure safe housekeeping are undertaken.  
• Develop health and safety procedures for evacuation in case of fire and make an announcement over the PA on instructions on how to evacuate building. 
• Report incidents involving fire system, alarm trigger, and any maintenance required to General Manager. 

QUALIFICATIONS

• A minimum education level of: High School Diploma or its equivalency  
• A minimum of 3-5 years of related work experience. 
• Certificate S98 or S95 required. 
• Proven experience as a Safety Officer. 
• Knowledge of OSHA/ADA laws and regulations.  
• Proficient in Microsoft Office Suite (Outlook, Word, and Excel) 
• Exceptional organizational skills and attention to detail. 
• Strong communication and interpersonal skills. 
• Ability to work in a fast-paced environment. 

Pay Scale: $18.21 - $25.71/hour 

Bonus: This position is not eligible for a bonus under the current bonus plan requirements.

Benefits: This position may be eligible for benefits (ACA qualification).

AEG reserves the right to change or modify the employee’s job description whether orally or in writing, at any time during the employment relationship. AEG may require an employee to perform duties outside his/her normal description.

Employer does not offer work visa sponsorship for this position.

Your Impact at LILA

We're building autonomous robotic systems that serve as the intelligent physical infrastructure of our Scientific Superintelligence Platform at Lila. To support our robotics research roadmap, we need to scale robot data collection to produce high-quality robot data, collected by humans, at scale, day after day while improving per-operator throughput, lowering churn, and keeping data quality consistent across every supervisor and shift

We're hiring an Operations Manager to own that scale-up end-to-end.

As Data Operations Manager, you'll own the day-to-day function that generates the training data powering Lila's robotic systems. That means managing the supervisors who run our data collection shifts, setting the conditions for consistent operator performance, and making sure every hour of work on the floor translates into high-quality, usable data for our research team.

This is a builder role. The team is early — a growing group of operators across two shifts — and the processes, metrics, and programs that will scale it are still being shaped. You'll design and own them. You'll report directly to the Robotics team and serve as the primary operational link between the floor and Robotics Research.

What You'll Be Building

• Run the operation: Own the day-to-day operation across all shifts. Set throughput targets, monitor adherence, debug when shifts under-deliver, and make weekly calls on staffing, scheduling, and task allocation
• Manage the team: You'll manage the supervisors who directly run our operators. Set clear goals, run a consistent performance loop, and grow the supervisory bench as shifts, and sites, expand
• Drive retention and engagement: Data collection is physical, repetitive, attention-heavy work. Design and continuously refine onboarding, training, performance incentives, recognition, and scheduling so operators stay engaged and the bar keeps rising. Approach this with a product mindset: hypothesize, ship, measure, iterate
• Own throughput and quality metrics. Set targets, build the dashboards, and run the review cadence that make performance visible across the team. Reduce reject rates, compress reset time, and increase usable hours per shift
• Plan capacity: Translate research priorities into concrete operational plans — operator allocation, supervisor coverage, equipment requirements, and risk. Forecast throughput, flag potential misses early, and re-plan as priorities evolve
• Scale the footprint: Partner with facilities, recruiting, and leadership to expand the operation across additional shifts and, in time, additional sites. Maintain an operational playbook that makes opening each new shift or site repeatable rather than bespoke
• Be the bridge to research: Meet with the research team to understand upcoming priorities: which tasks, which embodiments, what success looks like. Translate those needs into shift plans, and surface friction (poor reset ergonomics, ambiguous instructions, unreliable hardware) before it costs the team hours

What You’ll Need to Succeed

• 4+ years of operations or program management experience, including direct people management
• A track record of running shift-based, throughput-driven operations — ****warehousing, manufacturing, contact centers, data labeling, clinical ops, field operations or comparable
• Demonstrated success reducing churn or improving retention in a frontline workforce: We want to hear the specifics: the baseline, the intervention, and the outcome
• Comfort with metrics: You should be able to look at our shift summary, immediately spot what's interesting, and know what to ask for next
• Builder mindset: This is a function being built, not inherited. Some processes are still taking shape, and we are looking for the right person who sees that as an opportunity to grow and deliver
• Strong written communication — ****you will be the connection between the floor and research and engineering teams, and much of that work happens in documentation
• Willingness to be on-site and on-floor: This role depends on presence and proximity to the team

Bonus Points For

• Experience managing managers or building a supervisor layer from scratch
• Background in robotics, autonomous systems, or physical AI data collection
• Experience scaling a frontline team from under 20 to 100+
• Familiarity with workforce management software, shift-scheduling tooling, or QA workflow tools
• Background in industrial engineering, operations research, or a related quantitative field

Flagship Pioneering is a scientific innovation engine that invents and builds companies that change the world. We bring together the greatest scientific minds with entrepreneurial company builders and assemble the capital to allow them to take courageous leaps in human health, sustainability, and beyond. 

What sets Flagship apart is our ability to advance biotechnology by uniting life science innovation, company creation, and capital investment under one roof in a way that is largely without precedent. Our team of scientists, entrepreneurial leaders, and professional capital managers are each aligned around an institutionalized process that enables us to innovate and create breakthroughs for the benefit of people and planet.

Many of the companies Flagship has founded have addressed humanity’s most urgent challenges: vaccinating billions of people against COVID-19, curing intractable diseases, improving human health, preempting illness, and feeding the world by improving the resiliency and sustainability of agriculture.

Flagship has been recognized twice on FORTUNE’s “Change the World” list, an annual ranking of companies that have made a positive social and environmental impact through activities that are part of their core business strategies, and has been named four times to Fast Company’s annual list of the World’s Most Innovative Companies.

Position Overview

Flagship Pioneering is seeking an experienced and strategic Vice President or Senior Vice President, Total Rewards and People Operations to lead the design, management, and evolution of Total Rewards programs and key people infrastructure across our ecosystem. The scope of this role spans compensation, executive compensation, equity, benefits, people operations, and people analytics for Flagship and its portfolio of companies.

This is a highly visible leadership role requiring deep expertise in compensation strategy and private-company equity, as well as the ability to operate effectively across a complex, fast-paced, and highly matrixed environment. The ideal candidate will bring strong executive presence, sound judgment, and the ability to translate business strategy into scalable people programs that support growth, innovation, and organizational effectiveness.

This leader will oversee an established team across Compensation, Benefits, People Operations, and People Analytics, and will be expected to shape a modern, market-relevant Total Rewards philosophy, refine equity and incentive structures, advance benefits strategy, and drive people insights that support executive decision-making.

Key Responsibilities

Total Rewards Strategy and Leadership

• Lead the strategy, design, and ongoing evolution of Flagship’s global Total Rewards philosophy across compensation, executive compensation, equity, benefits, and other reward programs. 
• Serve as the principal architect of rewards strategy, recommending program direction to senior leadership and ensuring alignment with business priorities, talent strategy, and financial objectives. 
• Develop and refine salary structures, incentive frameworks, equity guidelines, and market positioning approaches across a global footprint. 
• Oversee job architecture and leveling governance in support of internal equity, talent management, and scalable compensation decision-making. 
• Guide annual compensation planning processes, including merit, bonus, promotion, and other pay actions, in partnership with HR, Finance, and business leadership. 
• Partner closely with Talent Acquisition and HR Business Partners on executive and broad-based offer strategy, market competitiveness, and internal equity. 
• Lead the continued evolution of executive compensation and broad-based equity strategy across Flagship and applicable portfolio companies. 

Equity and Incentive Design

• Provide strategic leadership for complex equity and long-term incentive programs, including private-company equity structures and alternative long-term incentive constructs. 
• Oversee equity strategy, governance, and operational execution through the team, ensuring strong program design and scalable administration. 
• Partner with senior leadership on the design and refinement of incentive and ownership frameworks that support attraction, retention, and long-term value creation. 
• Bring familiarity with innovative and non-traditional compensation approaches, including profits interests, carried interest, and related long-term incentive structures. 

Benefits Strategy

• Lead benefits strategy across health and welfare, retirement, leave, and ancillary programs, ensuring programs remain competitive, sustainable, and aligned with organizational values and workforce needs. 
• Partner with the Benefits leader and external advisors to evaluate plan design, funding, market trends, vendor performance, and evolving regulatory requirements. 
• Support harmonization and modernization of benefits strategy where appropriate across a diverse and growing ecosystem. 

People Operations

• Oversee key People Operations functions, including onboarding, offboarding, employee lifecycle processes, policy administration, compliance workflows, service delivery, and operational process excellence. 
• Ensure people processes are scalable, well-governed, and designed to support a high-quality employee and manager experience. 
• Partner effectively across HR, Payroll, IT, Legal, and Finance to improve operational efficiency and strengthen people-related infrastructure. 
• Provide leadership on HR compliance, as well as compensation- and benefits-related compliance considerations, in partnership with internal and external experts as appropriate. 

People Analytics

• Lead the People Analytics agenda, with an emphasis on generating insights that support executive decision-making across workforce planning, hiring, retention, compensation, and organizational effectiveness. 
• Oversee dashboards, reporting, and analytical frameworks that inform leaders including the CEO and CFO. 
• Translate data and analysis into actionable recommendations in partnership with HR Business Partners and business leaders. 
• Advance a thoughtful, increasingly sophisticated analytics capability that supports better people decisions across Flagship and the broader ecosystem. 

Portfolio Company Partnership

• Advise and support portfolio company leaders on Total Rewards strategy, with involvement calibrated to company stage, maturity, and business need. 
• Tailor rewards frameworks and guidance for a range of company stages while maintaining sound governance and alignment with broader talent and value creation goals. 
• Present recommendations and insights to portfolio company leadership and boards as needed. 

Leadership and Team Development

• Lead, develop, and inspire a multi-functional team spanning Compensation, Benefits, People Operations, and People Analytics. 
• Foster strong collaboration across functional teams and help continue building a high-performing, service-oriented, and strategically focused organization.
• Manage external consultants, brokers, survey providers, and other key vendors in support of rewards strategy and operational excellence. 

Qualifications

• 15+ years of progressive experience in Total Rewards, with significant depth in compensation strategy and experience leading broad, multi-functional teams. 
• Deep expertise in compensation design, market benchmarking, executive compensation, incentive strategy, and private-company equity. 
• Strong familiarity with alternative long-term incentive structures, including profits interests, carried interest, and other innovative ownership or reward constructs. 
• Experience leading or advising on benefits strategy, including health and welfare, retirement, leave, and ancillary offerings. 
• Experience overseeing or partnering closely with People Operations and People Analytics functions in complex organizations. 
• Demonstrated success operating in high-growth, founder-led, venture-backed, private equity, or similarly dynamic business environments. 
• Experience supporting global workforces and navigating matrixed organizations with multiple stakeholders and business models. 
• Strong executive presence with the ability to influence senior leaders, present compelling recommendations, and operate as a trusted advisor. 
• Proven ability to translate data and market insights into practical, business-relevant decisions and action plans. 
• Experience working with boards, founders, and senior executive stakeholders preferred. 
• Prior life sciences or biotechnology experience preferred, but not required. 

Why Join Flagship Pioneering?

This is a rare opportunity to play a critical role in shaping how a highly innovative organization rewards, supports, and scales exceptional talent. As Senior Vice President, Total Rewards and People Operations, you will operate at the intersection of business strategy, organizational design, and cutting-edge science, helping to build and evolve the people infrastructure that supports transformative work in human health and sustainability.

At Flagship, we recognize there is no perfect candidate. If you have some of the experience listed above but not all, please apply anyway. Experience comes in many forms, skills are transferable, and passion goes a long way. We are dedicated to building diverse and inclusive teams and look forward to learning more about your unique background.

Recruitment & Staffing Agencies: Flagship Pioneering and its affiliated Flagship Lab companies (collectively, “FSP”) do not accept unsolicited resumes from any source other than candidates. The submission of unsolicited resumes by recruitment or staffing agencies to FSP or its employees is strictly prohibited unless contacted directly by Flagship Pioneering’s internal Talent Acquisition team. Any resume submitted by an agency in the absence of a signed agreement will automatically become the property of FSP, and FSP will not owe any referral or other fees with respect thereto.

#LI-NM1

The salary range for this role is $300,000 - $400,000. Compensation for the role will depend on a number of factors, including a candidate’s qualifications, skills, competencies, and experience. Flagship Pioneering currently offers healthcare coverage, annual incentive program, retirement benefits and a broad range of other benefits. Compensation and benefits information is based on Flagship Pioneering's good faith estimate as of the date of publication and may be modified in the future.

Flagship Pioneering is a scientific innovation engine that invents and builds companies that change the world. We bring together the greatest scientific minds with entrepreneurial company builders and assemble the capital to allow them to take courageous leaps in human health, sustainability, and beyond. 

What sets Flagship apart is our ability to advance biotechnology by uniting life science innovation, company creation, and capital investment under one roof in a way that is largely without precedent. Our team of scientists, entrepreneurial leaders, and professional capital managers are each aligned around an institutionalized process that enables us to innovate and create breakthroughs for the benefit of people and planet.
Many of the companies Flagship has founded have addressed humanity’s most urgent challenges: vaccinating billions of people against COVID-19, curing intractable diseases, improving human health, preempting illness, and feeding the world by improving the resiliency and sustainability of agriculture.

Flagship has been recognized twice on FORTUNE’s “Change the World” list, an annual ranking of companies that have made a positive social and environmental impact through activities that are part of their core business strategies, and has been named four times to Fast Company’s annual list of the World’s Most Innovative Companies.

Position Summary

We are seeking a Contracts System Manager to serve as the primary owner and administrator of Flagship's Contract Lifecycle Management (CLM) and procurement systems. This individual will be responsible for system configuration, optimization, user support, training, and cross-functional collaboration to ensure the Legal, Procurement, and Finance teams can efficiently manage contracts across Flagship and its portfolio companies. The role requires significant interpersonal engagement—building trusted relationships across business units, influencing stakeholders to adopt new processes, and exercising judgment in navigating competing priorities that require human insight and contextual understanding.

The ideal candidate will have 3–5 years of experience administering CLM platforms (Cobblestone experience strongly preferred), a solid understanding of procurement workflows, and the ability to translate business requirements into technical system configurations. This role requires strong stakeholder engagement skills, attention to detail, and comfort working in a fast-paced, high-volume environment.

This is a great opportunity to join a company at the forefront of innovation in technology and science. We are looking for a self-motivated, entrepreneurial, and kind individual who works hard but doesn't take themselves too seriously. The team you would be joining is tight-knit and committed to helping one another succeed. 

Key Responsibilities

System Administration & Configuration

• Serve as the primary administrator for Flagship's CLM system (Cobblestone), including system configuration, user provisioning, role-based access control (RBAC), and permissions management 
• Design and configure contract workflows, approval routing logic, and dynamic intake forms based on agreement type, spend thresholds, department, or legal requirements—collaborating directly with business owners to understand their operational needs and secure buy-in on workflow changes
• Manage the company's contract templates, playbook terms, and clause libraries; configure new templates and process workflows as needed 
• Maintain repository accuracy, metadata tagging, and taxonomy; identify inefficiencies in current processes and propose workflow design improvements

Integration & Technical Operations

• Oversee and troubleshoot API connections and data syncs between the CLM system and downstream systems (e.g., ERP, procurement platforms, HRIS, e-signature tools) 
• Coordinate with IT on system integrations, security protocols, and technical requirements; serve as a trusted liaison between business functions, IT, and CLM vendor, translating technical constraints into business-friendly explanations and advocating for user needs in system design decisions
• Test and deploy system updates, patches, and new features from vendors; manage change control to minimize disruption to business users 
• Configure and maintain vendor management modules, ensuring seamless data capture and risk assessment during vendor onboarding

User Support & Training

• Provide Tier 1 and Tier 2 support for CLM system users, including day-to-day troubleshooting, resolving workflow stalls, and addressing error messages 
• Onboard and train new users (both technical and non-technical) on CLM system functionality and related processes through hands-on coaching, live demonstrations, and personalized support; implement train-the-trainer models and adapt training approaches based on individual learning styles and departmental needs
• Develop and maintain CLM training materials, user guides, and Standard Operating Procedures (SOPs); gather user feedback and recommend process improvements
• Support onboarding of new Flagship portfolio companies onto established contract standards and CLM processes, serving as a dedicated point of contact who builds rapport with new teams, addresses concerns with empathy, and guides stakeholders through change management during organizational transitions

Cross-Functional Collaboration & Stakeholder Engagement

• Act as the primary liaison between IT and Finance, Legal, and Procurement teams, translating business processes into technical system requirements 
• Build and maintain strategic relationships with business colleagues across Flagship and portfolio companies to understand evolving contracting needs, anticipate workflow challenges, and influence adoption of standardized processes through trust, credibility, and demonstrated value
• Coordinate directly with external vendors, counterparties, and law firms on contract logistics and system-related clarifications, exercising diplomacy and sound judgment to resolve ambiguities, manage expectations, and maintain productive working relationships

Reporting & Analytics

• Build dashboards and generate contract metrics to inform Legal leadership and cross-functional stakeholders; analyze trends and provide recommendations to improve contract operations efficiency, presenting findings in stakeholder meetings and facilitating discussions to drive consensus on operational improvements
• Conduct regular system audits to monitor data integrity, system health, and key performance metrics (e.g., approval cycle times, contract turnaround) 
• Track key dates and milestones; proactively identify and escalate potential risks, such as approaching deadlines, renewal windows, or expiring terms requiring action

Compliance & Process Improvement

• Participate in assessing, refining, and executing on future business requirements for the CLM system; contribute to template and playbook updates based on recurring issues and counterparty redline patterns 
• Support compliance with life sciences regulatory requirements (FDA, GxP where applicable) by ensuring contract workflows and documentation meet audit and traceability standards
• Identify and recommend process improvements to enhance efficiency, compliance, and user adoption across the contracting process

Required Qualifications

• Bachelor's degree in Business, Information Systems, Legal Studies, or related discipline 
• 3–5 years of experience as a CLM systems administrator, legal operations specialist, or similar role 
• Proficiency with contract lifecycle management (CLM) systems and associated workflows; hands-on experience with system configuration, workflow design, and user administration 
• Understanding of procurement and finance processes, including budgets, payment terms, and vendor engagement 
• Experience developing and implementing system-driven workflows; comfort with Jira or similar tools for user story creation and tracking 
• Strong written and verbal communication skills with excellent stakeholder engagement ability, including the capacity to influence without authority, navigate organizational dynamics, and build consensus among diverse business partners
• Ability to exercise independent judgment in prioritizing workflow, escalating appropriately, and making nuanced decisions that balance competing stakeholder interests and business objectives
• Experience troubleshooting CLM or workflow system issues; ability to promptly identify and solve software and process problems 
• Detail-oriented with strong organizational and project management skills 
• Ability to multi-task and work independently in a fast-paced environment; prioritize workflow based on business objectives

Preferred Qualifications

• Experience in biotech, life sciences, pharmaceutical, or regulated industries 
• Experience configuring or administering Cobblestone CLM system (taxonomy, permissions, template maintenance, workflow configuration) 
• Familiarity with Coupa or other procurement system integration 
• Experience with contract intake and legal operations frameworks 
• Exposure to commercial agreements and legal terms and conditions 
• Experience leading or actively participating in CLM system implementation projects 
• Familiarity with FDA regulations, GxP requirements, or clinical contracting in life sciences environments
• Proficiency with business applications such as Microsoft 365, Coupa, Cobblestone, DocuSign, and Adobe Acrobat 
• Ability to work in a scrum/agile environment

Culture & Values (Flagship)

We seek individuals who reflect Flagship's culture of fearless exploration, entrepreneurial thinking, and collaborative impact. You thrive in environments that require creative problem solving, strong ownership, and alignment with mission-driven outcomes. 

Work Environment & Benefits

• Standard office environment in Cambridge with hybrid and remote flexibility options
• Collaborative, interdisciplinary teams engaged in high-impact innovation 
• Professional growth opportunities across Flagship Pioneering and its portfolio 
• Competitive compensation and benefits package

Equal Opportunity Employer

Flagship Pioneering is an Equal Opportunity Employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, national origin, disability, or protected veteran status. 

#LI-NM1

The salary range for this role is $108,000 - $148,000. Compensation for the role will depend on a number of factors, including a candidate’s qualifications, skills, competencies, and experience. Flagship Pioneering currently offers healthcare coverage, annual incentive program, retirement benefits and a broad range of other benefits. Compensation and benefits information is based on Flagship Pioneering's good faith estimate as of the date of publication and may be modified in the future.

Flagship Pioneering is a scientific innovation engine that invents and builds companies that change the world. We bring together the greatest scientific minds with entrepreneurial company builders and assemble the capital to allow them to take courageous leaps in human health, sustainability, and beyond. 

What sets Flagship apart is our ability to advance biotechnology by uniting life science innovation, company creation, and capital investment under one roof in a way that is largely without precedent. Our team of scientists, entrepreneurial leaders, and professional capital managers are each aligned around an institutionalized process that enables us to innovate and create breakthroughs for the benefit of people and planet.
Many of the companies Flagship has founded have addressed humanity’s most urgent challenges: vaccinating billions of people against COVID-19, curing intractable diseases, improving human health, preempting illness, and feeding the world by improving the resiliency and sustainability of agriculture.

Flagship has been recognized twice on FORTUNE’s “Change the World” list, an annual ranking of companies that have made a positive social and environmental impact through activities that are part of their core business strategies, and has been named four times to Fast Company’s annual list of the World’s Most Innovative Companies.

Role Summary

We are seeking a Contract Manager to join our in-house legal team and support Flagship’s enterprise operations. This individual will manage the full lifecycle of standard commercial agreements—drafting, reviewing, negotiating, and executing contracts—with a focus on IT, SaaS, real estate, facilities, and services agreements that enable the Flagship enterprise to operate more efficiently and effectively. The ideal candidate will have 4+ years of relevant contract management experience, proven ability to negotiate template-based agreements with attorney oversight, and strong familiarity with contract management systems and cross-functional stakeholder engagement.

This is a great opportunity to join a company at the forefront of innovation in technology and science. We are looking for a self-motivated, entrepreneurial, and kind individual who works hard but doesn’t take themselves too seriously. The team you would be joining is tight-knit and committed to helping one another succeed.

Key Responsibilities

• Manage the full lifecycle of standard commercial agreements—including IT/SaaS agreements, real estate and facilities contracts, MSAs, SOWs, consulting agreements, and CDAs—from drafting through negotiation, execution, and renewal.
• Draft and negotiate standard template-based agreements with attorney oversight; assess legal, financial, and operational risks and escalate non-standard terms to counsel as appropriate.
• Use contract management tools to monitor workflows, track milestones, and ensure timely renewals or amendments; maintain repository accuracy and optimize CLM system processes.
• Support cross-functional teams—including Finance, Procurement, IT, Facilities, and R&D—by advising on key contract terms such as indemnities, confidentiality, service levels, and liabilities, with attorney oversight for non-standard terms.
• Track and monitor key contract milestones, deliverables, and compliance obligations.
• Collaborate with internal and external stakeholders to streamline contract processes, improve efficiency, and enhance enterprise operations.
• Provide guidance to internal partners on contract submission practices and standard language.
• Generate data-driven insights from contract analytics to improve reporting, decision-making, and operational performance; assist Contracts Administrators with contract entry as necessary.

Required Qualifications

• Bachelor’s degree in Business, Legal Studies, Finance, or related discipline.
• 4+ years of relevant work experience managing contracts, including drafting and negotiating standard commercial agreements.
• Experience utilizing contract management tools to automate workflows, track contract milestones, and ensure timely renewals; familiarity with AI-powered tools for document review, redlining, and finalization.
• Familiarity with key legal and regulatory issues affecting contracts, such as confidentiality, indemnification, liability, and data privacy.
• Strong written and verbal communication skills with excellent stakeholder engagement ability.
• Prior experience managing a high volume of contracts with various stakeholders under tight timelines.
• Highly self-motivated and driven.
• Thrives independently in fast-paced, evolving corporate environment.
• Proactive involvement beyond core responsibilities.

Polished and professional demeanor.Preferred Qualifications

• Experience with IT/SaaS agreements, real estate and facilities contracts, and other operational agreements in a corporate or enterprise environment.
• Experience configuring or administering CLM systems (e.g., taxonomy, permissions, template maintenance).
• Experience in biotech, life sciences, venture capital, or regulated industries.
• Familiarity with ERP systems and integration with contract workflows.

Culture & Values (Flagship)

We seek individuals who reflect Flagship’s culture of fearless exploration, entrepreneurial thinking, and collaborative impact. You thrive in environments that require creative problem solving, strong ownership, and alignment with mission-driven outcomes. . 

Work Environment & Benefits

• Standard office environment in Cambridge with hybrid and remote flexibility options
• Collaborative, interdisciplinary teams engaged in high-impact innovation 
• Professional growth opportunities across Flagship Pioneering and its portfolio 
• Competitive compensation and benefits package

Equal Opportunity Employer

Flagship Pioneering is an Equal Opportunity Employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, national origin, disability, or protected veteran status. 

#LI-NM1

The salary range for this role is $108,000 - $148,000. Compensation for the role will depend on a number of factors, including a candidate’s qualifications, skills, competencies, and experience. Flagship Pioneering currently offers healthcare coverage, annual incentive program, retirement benefits and a broad range of other benefits. Compensation and benefits information is based on Flagship Pioneering's good faith estimate as of the date of publication and may be modified in the future.

The Opportunity:

As Associate Director, Data Management, you will be accountable for delivery, integrity, and quality of Relay’s clinical data across the clinical studies. You will be an integrated member of the Relay Tx scientific team, responsible for the in-house data management expertise for the execution of clinical studies that will translate Relay’s innovative science into impactful medicines for patients. You will report to the Senior Director, Clinical Data Management.  

Your Role:  

• You will be responsible for oversight and execution of data management activities for assigned clinical programs including data timelines and key deliverables.  

• You will work directly with and oversee CROs and vendors for outsourced Data Management activities. Is responsible for CRO performance and data management metrics for assigned programs. 

• You will lead database development and eCRF design, UAT, data import specifications, Case Report Form completion guidelines, data entry guidelines and related operations manuals.  

• You will lead data validation specifications and programs for assuring the accuracy of clinical trial data, e.g., manual data review guidelines, computerized edit check programs, Data Management Plans (DMP). 

• You will be responsible for executing or overseeing data cleaning activities through to database lock: includes generating and managing clinical trial data queries, data review listings, coding specified clinical trial data, e.g. adverse events and concomitant medications, reconciling serious adverse events and central labs.  

• You will collaborate with a dynamic Relay cross-functional team to ensure timeliness and quality of data deliverables. 

• You will ensure compliance with global regulatory requirements and quality standards. 

• You will contribute to data standards including CRF and participate in data system development initiatives and database integration projects. 

• You will participate in SOP development, training of junior data managers, process mapping, and other departmental activities. 

Your Background:  

• You should ideally have 7+ years of experience in the pharmaceutical / biotechnology industry as a Data Manager.  Sponsor experience is strongly preferred. 

• You have advanced experience with data collection and cleaning covering Phase I, II and III studies. Oncology experience is preferred. 

• You have experience in executing clinical studies across various phases is desirable.  Expertise in oncology drug development is preferred.         

• You have a strong and current knowledge in global regulatory and compliance requirements including but not limited to US CFR, EU CTD, ICH GCP, and CDISC.       

• You have experience in CRO and vendor oversight.          

• You are a motivated self-starter who is capable of flourishing in a fast-paced small company environment. 

• You are a creative problem-solver with excellent communication and public speaking skills.          

• You have strong interpersonal and organizational skills, with a high degree of attention to detail.       

• You are pragmatic and able to manage multiple projects and needs effectively. 

Estimated Salary Range: [$146,000 - $208,000].

The range provided above is based on what we believe to be a reasonable estimate for this job at the time of posting. Actual base salary will depend on a number of factors, including but not limited to, a candidate’s education, experience, skills and location.

#BP1

The Opportunity

We are seeking a highly motivated Manager of Financial Planning & Analysis (FP&A) to join our established finance team at a well-positioned, clinical-stage precision medicine company in Kendall Square. This is an excellent opportunity for a finance professional who thrives in a dynamic, collaborative environment and is eager to make a meaningful impact across the organization.

This role will report to the Senior Director of FP&A and will play a key role in supporting our development organization through accrual reporting, planning, and analytical activities as well as supporting our recurring management reporting deliverables

Your Role

• Track and analyze clinical site budgets, providing visibility into spend and key trends
• Support the analytics for our clinical trials including the clinical accruals process, and business partnering with key cross-functional stakeholders
• Preparation and delivery of key monthly reporting including monthly financial reporting and headcount analytics
• Trusted FP&A business partner to our G&A departments (Finance, IT, HR, Legal, and Operations)
• Perform ad hoc financial analysis to support decision-making across the development organization
• Assist with budgeting, forecasting, and long-range planning processes
• Prepare presentations and materials for cross-functional partners, translating data into clear and compelling financial insights
• Continuously improve financial processes, models, and reporting tools

Your Background

• Bachelor’s degree in Accounting, Finance, or related field (required)
• 5+ years of progressive experience in finance or accounting (biotech or life sciences experience preferred)
• Strong proficiency in Microsoft Excel and PowerPoint (required)
• Experience with Adaptive Planning or similar financial planning tools (preferred)
• Solid understanding of financial statements, budgeting, and forecasting processes
• Strong analytical, problem-solving, and communication skills
• Ability to manage multiple priorities and work effectively in a fast-paced environment
• Detail-oriented with a high degree of accuracy and accountability

Why Join Us?

• Join a collaborative, well-established finance team
• Contribute to a mission-driven company making a meaningful impact for patients
• Gain exposure to cross-functional teams and senior leadership
• Opportunity for growth and professional development

If you're looking to take the next step in your finance career and want to contribute to a high-impact organization, we’d love to hear from you.

Estimated Salary Range: [$98,000 - $140,000].

The range provided above is based on what we believe to be a reasonable estimate for this job at the time of posting. Actual base salary will depend on a number of factors, including but not limited to, a candidate’s education, experience, skills and location.

#BP1

Prime Medicine was founded to bring the promise of gene editing to patients. We use Prime Editing, a next-generation technology that can “search and replace” to restore normal genetic function almost anywhere in the genome. Prime Editing searches to find the precise place in the genome to edit and replaces the segment of faulty DNA with a correct copy of DNA.  A single Prime Editor can correct the individual mutations found across patients, meaning Prime Editing can potentially address more than 90 percent of known disease-causing genetic mutations. 

We envision a world where this technology can cure, halt, and ultimately prevent genetic diseases, providing lifelong benefit to patients.  Prime Medicine offers the opportunity to shape the future of gene editing and transform how medicines are used to treat disease. Realizing the promise of Prime Editing requires a talented team with diversity of viewpoints and expertise. We’re building a group of dedicated, scientifically curious individuals who are passionate about helping patients live longer, healthier lives.

Position Overview

Prime Medicine is seeking a talented and motivated Sr. Manager to join the Analytical Development & QC team within Technology, Development & Operations. This role will focus on Quality Control (QC) related activities for all programs, including management and technical oversight of tech transfer, qualification/validation and release and stability testing carried out at both CDMOs, CTLs and internally at Prime for our prime editing ex vivo cell therapy and in vivo LNP-based drug products.

The successful candidate will have deep understanding of method lifecycle management, including method optimization, qualification, validation/verification, transfer, and implementation in a cGMP environment, as well as previous hands-on experience in at least some aspects of the above. This is a role requiring strong cross-functional collaboration with Analytical Development, Quality, Process Development, Formulation, Informatics, and external partners (CTLs/CDMOs). 

The ideal candidate thrives in a matrixed, fast-paced environment, works effectively with limited supervision, and demonstrates strong technical ownership and execution.

Key Responsibilities

• Design or review analytical procedures and protocols supporting method lifecycle activities, including optimization, qualification, validation, transfer, verification, performance monitoring, bridging, and comparability studies
• Manage and conduct select release, stability, and in-process testing for drug substances, drug products, and gene-editing components, and carry out data analysis and trending
• Support and/or manage analytical method transfer to CTLs/CDMOs, providing oversight, troubleshooting, and ensuring technical and timeline objectives are met
• Manage GMP sample inventory and chain-of-custody documentation
• Lead, manage and maintain well-designed stability programs and reference standard programs
• Author and review protocols, reports, SOPs, and analytical sections of regulatory submissions
• Familiarity with and ability to learn and use new tools for productivity, project management, documentation, tracking scheduling, and data management.
• Support IQ/OQ/PQ of QC equipment and ensure compliance with 21 CFR Part 11
• Maintain GxP-compliant electronic documentation and thorough laboratory records
• Collaborate with Quality to ensure data integrity, regulatory compliance, and audit readiness
• Lead or support investigations, deviations, and root-cause analyses
• Present data and findings to cross-functional teams
• Prepare technical reports and documents for global regulatory submissions

Qualifications

Education & Experience

• BS/MS/PhD in Biochemistry, Molecular biology, Chemistry, Bioengineering, or a related discipline
• Industry experience:
• BS: 10+ years
• MS: 8+ years
• PhD: 3+ years

Technical Expertise

• Experience with analytical method optimization, tech-transfer, qualification, validation, and verification used for critical components, drug substance and drug product release and stability testing
• Hands-on experience with analytical methodologies such as:
• Chromatography-based assays
• Absorbance-based assays
• Cell-based assays
• Compendial assays
• Molecular-based assays
• Flow cytometry assays
• Familiarity with ICH and FDA guidelines for CMC development during clinical stage is required
• Experience in advanced cell and gene-editing therapeutics development is not mandatory, but highly desirable
• Experience working with CMOs/CDMOs is required
• Experience with stability and/or reference standard programs is a plus
• Knowledge of assays, instrumentation, and facility qualification/validation requirements is desirable
• Familiarity with regulatory writing

Personal Attributes

• Highly self-motivated with strong project ownership
• Strong collaborator with internal cross-functional and external partners
• Adaptable in a dynamic, fast-paced environment
• Detail-oriented with strong troubleshooting and problem-solving skills
• Excellent written and verbal communication skills
• Strong abilities to lead and facilitate technical meetings with CDMO and CTL SMEs
• Work with purpose and drive meaningful results
• Ability to innovate and challenge industry status quo
• Ability to travel for up to 5 - 10% of the time

Prime Medicine is proud to be an equal opportunity employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, national origin, sexual orientation, gender identity, disability, protected veteran status, or any other characteristic protected by law.

What if… you could join an organization that creates, resources, and builds life sciences companies that invent breakthrough technologies to transform human health and sustainability?

Flagship Pioneering's venture creation engine has conceived and created companies such as Moderna Therapeutics (NASDAQ: MRNA), Rubius Therapeutics (NASDAQ: RUBY), Sana Biotechnology (NASDAQ: SANA), Generate Biomedicines, and Tessera Therapeutics. Since its launch in 2000, Flagship has applied its unique hypothesis-driven innovation process to originate and foster more than 100 scientific ventures, resulting in over $212 billion in aggregate value. To date, Flagship has deployed over $2.5 billion in capital toward the founding and growth of its pioneering companies alongside more than $19 billion of follow-on investments from other institutions. In 2021, Flagship Pioneering was ranked 12thglobally on Fortune’s “Change the World” list, an annual ranking of companies that have made a positive social and environmental impact through activities that are part of their core business strategies.

The Company:

FL116, backed by Flagship Pioneering, is an early-stage biotechnology company transforming the way biomolecules are synthesized. Our innovative platform has the potential to redefine how critical research, diagnostic, and therapeutic molecules are designed and built. We are seeking passionate problem solvers ready to make a profound impact on biotechnology and therapeutic innovation. 

Position Summary:

The Senior Manager of Corporate Development and Enablement will serve as a key strategic and operational partner to the President, driving high-priority initiatives across corporate development, partnerships, investor/board communications, operations, and market-informed product strategy. Operating at the center of the organization, this individual will work cross-functionally with scientific and business leaders to translate complex technical and market insights into clear strategies and actionable plans. The ideal candidate thrives in ambiguity, brings a structured, analytical approach to problem-solving, and is equally comfortable shaping strategy and executing against it in a fast-paced, early-stage biotechnology environment.

Responsibilities:

• Reporting to the president, the successful candidate will lead creation of external/internal company presentations/reports, including board material, pitches and other critical documents
• Convene the weekly company leadership team meeting, managing the agenda and key action items that emerge from the discussion
• Coordinate our major external partnership, ensuring our timelines/budget remain on track, aligning stakeholders, and preparing key update materials
• Support establishment of key vendor relationships, shepherding SOWs, MSAs, and other legal agreements through our approval processes, then tracking deliverables
• Ensure our lab operations and lab space are meeting the company needs; Driving real estate and equipment sourcing strategies.
• Conduct market research with relevant customers, building out product strategies
• Support broader strategic decision making, such as corporate/partnership strategies

Qualifications:

• At least 2 years working in a strategy or strategic-consulting role, ideally with R&D experience; PhD in a technical field is beneficial but not required.
• Deep knowledge and understanding of life sciences. Proficient in distilling key insights from across multiple scientific sources and driving towards conclusions.
• Preference for candidates with proven experience in product strategy, market research, or R&D strategy preferred

Who You Are

• Execution focused and motivated: You thrive in getting things done efficiently and continuing to advance the mission of FL116.
• Collaborative Contributor: You excel in cross-functional teams, readily share expertise, and value the input of colleagues.
• Inventive Problem Solver: You proactively identify challenges and rapidly ideate creative solutions.
• Compelling storyteller: You can translate ideas, both yours and others, into high quality and well-structured communications in any medium, including spoken, presentation, or memo formats.

Location: Cambridge, MA 

Flagship Pioneering and our ecosystem companies are committed to equal employment opportunity regardless of race, color, ancestry, religion, sex, national origin, sexual orientation, age, citizenship, marital status, disability, gender identity or Veteran status.

 Recruitment & Staffing Agencies: Flagship Pioneering and its affiliated Flagship Lab companies (collectively, “FSP”) do not accept unsolicited resumes from any source other than candidates. The submission of unsolicited resumes by recruitment or staffing agencies to FSP or its employees is strictly prohibited unless contacted directly by Flagship Pioneering’s internal Talent Acquisition team. Any resume submitted by an agency in the absence of a signed agreement will automatically become the property of FSP, and FSP will not owe any referral or other fees with respect thereto.

The salary range for this role is $139,000 - $176,000. Compensation for the role will depend on a number of factors, including a candidate’s qualifications, skills, competencies, and experience. FL116 currently offers healthcare coverage, annual incentive program, retirement benefits and a broad range of other benefits. Compensation and benefits information is based on FL116's good faith estimate as of the date of publication and may be modified in the future.

Why Join Us?

Parabilis Medicines is a clinical-stage biopharmaceutical company dedicated to creating extraordinary medicines that unlock high-impact protein targets long-considered undruggable. The company has developed a new class of stabilized, cell-penetrant alpha-helical peptides – Helicons™ – capable of modulating intracellular proteins that are inaccessible to traditional drug modalities. 

Headquartered in Cambridge, Mass., Parabilis is advancing a focused pipeline of multiple first-in-class therapies across both rare and common cancers. Its lead asset, zolucatetide (FOG-001), is a first-in-class, clinically validated direct inhibitor of the interaction between β-catenin and the T-cell factor (TCF) family of transcription factors, implicated in millions of cancer cases annually, including in colorectal cancer, desmoid tumors, hepatocellular carcinoma and a range of other Wnt/β-catenin-driven tumors. In Phase 1 clinical trials, zolucatetide produced the first-ever clinical evidence that it can directly inhibit this interaction, once previously considered “undruggable” despite its role across multiple cancer types. Parabilis is also advancing investigational degraders of ERG and AR^ON into clinical development for the treatment of prostate cancer, as well as progressing other preclinical programs. Backed by a recent $305 million Series F financing, Parabilis is entering an exciting phase of growth and execution.

What’s the opportunity?

The Senior Manager, Supply Chain will lead the end-to-end operational management of investigational product (IP) and clinical trial materials across global Phase I–III studies. This role is responsible for ensuring timely, compliant, and efficient delivery of clinical supplies, while partnering cross-functionally with Clinical Operations, Quality, Regulatory, CMC, and external vendors to support study execution.

• Develop and maintain study-level supply plans and forecasts aligned with enrollment, protocol design, and site activation timelines
• Coordinate packaging, labeling, release, and global distribution of investigational products and ancillary materials
• Oversee inventory across depots and study sites, proactively mitigating risks to avoid shortages or excess
• Serve as business owner of the IRT system, including setup, configuration, validation, and ongoing management
• Partner cross-functionally to align supply strategy with clinical and regulatory requirements and ensure seamless execution
• Author and maintain supply-related documentation, including SOPs, Pharmacy Manuals, and study-specific materials
• Ensure compliance with GxP, GDP, and ICH-GCP standards, supporting audits and inspection readiness
• Manage global logistics, vendor oversight, and third-party partners to ensure uninterrupted supply across regions

What you’ll need to be successful:

• Bachelor’s degree in Supply Chain, Life Sciences, or related field (Master’s preferred)
• Minimum 5 years of global clinical supply chain experience within biotech, pharma, or medical device
• Hands-on experience with IRT/IXRS systems (e.g., 4G Clinical, Almac, Endpoint)
• Experience supporting global Phase I–III clinical trials (commercial launch experience preferred)
• Proficiency with Microsoft Office and inventory/ERP systems
• Strong understanding of GxP, GDP, and ICH-GCP regulations
• Proven ability to manage complex global supply operations and mitigate risk
• Strong analytical, organizational, and problem-solving skills
• Effective cross-functional collaboration and communication across internal teams and external partners
• Experience drafting SOPs, Pharmacy Manuals, and clinical supply documentation preferred
• Familiarity with cold chain and temperature-controlled distribution preferred
• APICS/CSCP or PMP certification a plus
• Demonstrated ability to utilize AI tools for day-to-day work; baseline proficiency is expected, and advanced or innovative use of AI is a strong plus
• Able to work on-site and attend in-person meetings
• Ability to travel up to 15%

Core Values

Parabilis is a team of passionate pioneers who are trailblazing the future of precision medicine with the aim of making a meaningful difference in the lives of patients. The company is committed to promoting an inspiring and flourishing working environment for all employees across the business, in all departments, and driving innovation for patient benefit.

• Growth-Minded. We’re inventing a new class of medicines—one applicable to therapeutic targets that have been dreamt about, but always considered impossible to drug. Our work requires us to be curious, humble and adaptable.
• In(ter)dependent.We are fiercely independent as a leader in defying the limitations of current therapeutic modalities, and interdependent as a team as we work collaboratively to shift drug discovery paradigms and provide patients with better treatment options.
• Patient-focused.We are deeply focused on patient outcomes, and all energy in the company is focused on science as it translates to patient impact.
• All-In.We’re All-In on solving some of the hardest scientific challenges and delivering one of the most effective new classes of drugs in history.

The base salary target for this position is $153,000-$180,000 per year, depending on experience, qualifications, and internal practices. Parabilis’s total compensation package also includes an annual target bonus, equity, and a comprehensive suite of competitive benefits designed to support our employees’ overall well-being.

As an equal opportunity employer, Parabilis values an inclusive workplace and welcomes applicants of all backgrounds and experiences. All qualified applicants will receive consideration for employment without discrimination on the basis of race, color, religion, sex, sexual orientation, gender identity, national origin, protected veteran status, disability, or any other factors prohibited by law.

30 Acorn Park Drive    |     Cambridge, MA 02140    |    www.parabilismed.com

Are you looking for a change in your career, are you an ambitious, talented and a motivated individual? This could be the role for you!

An opportunity has arised in our Marketing team who play a pivotal role in driving the company's growth by strategically positioning and promoting our innovative FISH and NGS products across research, clinical, and pharma markets.

As a Product Manager for FISH at OGT, your primary responsibility is to drive the success of our fluorescence in situ hybridization (FISH) product portfolio. You will join our Product Management team who are entrusted with overseeing the entire lifecycle of our products, from conception through to launch and ongoing optimization. Your role involves understanding market trends, customer needs, and competitive landscapes to develop and execute strategic product plans.

Your duties will include:

• Conduct comprehensive market research and analysis to gather the voice of the customer, identifying key needs, pain points, and market trends
• Analyse market trends, competitive landscapes, and customer feedback to identify opportunities for product innovation and differentiation
• Establish and maintain relationships with key opinion leaders, customers, and strategic partners to leverage their insights and connections for market intelligence
• Collaborate closely with Sales teams to leverage their market knowledge and insights, integrating their input into the VoC strategy and ensuring alignment between customer feedback and business objectives
• Collaborate with cross-functional teams to drive new product development (NPD) ideation, ensuring alignment with company goals and customer requirements
• Provide strategic input into product roadmap planning, prioritizing features and enhancements based on VoC findings and business objectives
• Develop robust business cases for new product initiatives, including market opportunity assessment, financial projections, and risk analysis
• Lead the product launch process, coordinating activities across marketing, sales, operations, and support functions to ensure a successful market introduction
• Define product positioning, messaging, and value propositions based on customer insights and competitive analysis
• Develop go-to-market strategies for new product launches, incorporating VoC insights to optimize pricing, distribution, and promotional tactics
• Oversee the development of global marketing campaigns to effectively position and promote products in target markets
• Collaborate with sales teams to develop sales enablement tools, training materials, and collateral to support product selling efforts
• Monitor product performance and customer feedback post-launch, iterating on strategies and tactics to optimize product success
• Act as a subject matter expert for the product portfolio, providing guidance and support to internal teams and external stakeholders
• Drive continuous improvement initiatives to enhance product quality, features, and user experience based on market feedback and technological advancements.

What we’re looking for in you:

Essential

• Degree level education in a molecular biology discipline
• Previous experience in a global Product Management role in Life Sciences, Genomics, or in vitro diagnostics Knowledge of FISH, ideally in a clinical setting
• Comprehensive knowledge and keen interest in developing applications, new technology and uptake in clinical and diagnostic applications
• Customer focused
• Strong analytical skills
• Able to travel for up to 20% of their working time, including internationally.

Desirable

• Experience in clinical cytogenetics, molecular genetics, or cancer genetics
• 1-2 years lab experience in NGS and/or FISH
• Proven track record of success in growing or supporting sales in clinical molecular genetics, diagnostics, or cancer genetics markets, including managing relationships with key customers/opinion leaders in their field
• A successful track record in product management and/or product development.

In return you will receive:

• Competitive salary
• Company Bonus Scheme
• Pension Scheme (10% non-contributory)
• Private Health Insurance
• Private Dental Insurance
• Group Income Protection
• Group Life Assurance
• 25 days holiday plus UK bank holidays
• High Street Discount Scheme.

Your Impact at LILA

We are seeking a highly organized and proactive Administrative Coordinator to provide operational and administrative support to our Government Affairs team in Washington, D.C. This role is the operational backbone of the team and ensuring the Government Affairs office can focus on its core efforts. The ideal candidate is a self-starter who thrives in a fast-paced, politically dynamic environment and exercises sound judgment and discretion at all times. This role requires 5 days a week in office in Washington, DC.

What You'll Be Building

GA Team Support 

• Manage scheduling for government affairs team, including scheduling meetings with Members of Congress, agency officials, and coalition partners
• Coordinate domestic and international travel logistics, including flights, hotels, ground transportation, and itineraries
• Prepare and process expense reports, invoices, and reimbursements in a timely manner
• Draft, proofread, and edit correspondence, briefing materials, talking points, and internal memos
• Anticipate executive needs and proactively handle administrative matters with minimal direction

Office Management

• Oversee day-to-day office operations, serving as the primary point of contact for building management, vendors, and service providers
• Manage office supply inventory, equipment maintenance, and facilities needs
• Onboard new team members, including coordinating workspace setup, badge access, and IT provisioning
• Maintain organized filing systems for legislative documents, regulatory filings, lobbying disclosures, and compliance records
• Coordinate with IT support to troubleshoot technology issues and manage software subscriptions

Legislative & Government Affairs Support 

• Assist with the preparation and timely filing of lobbying disclosure reports (LDA filings) in coordination with compliance counsel
• Maintain and update contact databases for congressional offices, agency contacts, and external stakeholders
• Coordinate logistics for Capitol Hill meetings, fly-ins, briefings, receptions, and fundraising events with external consultants
• Support the preparation of leave-behinds, one-pagers, and materials for Congressional meetings

Events & Stakeholder Coordination

• Plan and execute team events, including staff retreats, coalition meetings, roundtables, and receptions
• Manage coordination including invitations, RSVPs, catering, AV setup, and venue coordination
• Liaise with external partners, trade associations, and consulting firms on joint events and initiatives

What You’ll Need to Succeed

• 3–5 years of experience in an executive assistant, office manager, or administrative role, preferably in public service, government affairs, lobbying, law, or public policy environment
• Strong familiarity with the Washington, D.C. political landscape, including how Congress and federal agencies operate
• Exceptional organizational skills with the ability to manage multiple priorities under tight deadlines
• Outstanding written and verbal communication skills
• High degree of professionalism, discretion, and judgment when handling sensitive or confidential information
• Proficiency in Microsoft Office Suite (Outlook, Word, Excel, PowerPoint) and collaboration tools (e.g., Teams, Zoom, Slack)
• Ability to travel up to 10% of the calendar year, including international travel
• Ability to be in office 5 days a week in Washington, DC

Preferred

• Experience supporting C-suite executives or senior government officials
• Familiarity with Lobbying Disclosure Act (LDA) compliance and reporting requirements
  • Experience with stakeholder or contact management platforms (e.g., Quorum, Fireside, Salesforce)
  • Familiarity with political giving processes, including PAC administration, contribution tracking, and FEC reporting requirements
• Bachelor's degree in political science, public policy, communications, business, or a related field

Bonus Points For

• Discretion & Professionalism — Handles sensitive political and organizational information with the utmost confidentiality
• Proactive Problem-Solving — Anticipates issues and resolves them before they escalate
• Attention to Detail — Produces accurate, polished work products consistently
• Adaptability — Remains calm and effective in a dynamic, high-stakes environment
• Relationship Management — Builds trusted relationships with internal stakeholders, congressional staff, and external partners

Your Impact at LILA

We are seeking a detail-oriented and highly collaborative Revenue Manager to own the operational execution of revenue accounting for licensing, collaboration, and other complex revenue agreements. This role sits within the finance function and focuses on ensuring accurate, timely, and scalable revenue processes, partner reporting, and billing operations.

What You'll Be Building

Revenue Operations & Execution

• Own day-to-day revenue accounting operations for collaboration, licensing, and other revenue-generating agreements
• Translate contract terms into operational workflows for revenue recognition, billing, and reporting
• Ensure revenue is recorded accurately and consistently in accordance with established accounting policies

Contract Interpretation & Application

• Review revenue agreements and summarize key accounting and operational terms (e.g., billing triggers, milestones, deliverables)
• Apply ASC 606 principles to support proper treatment of revenue, in partnership with technical accounting where needed
• Serve as a bridge between technical accounting conclusions and operational execution

Close & Reporting

• Lead monthly and quarterly close activities for revenue, including journal entries and reconciliations
• Maintain supporting schedules and ensure completeness and accuracy of revenue balances
• Support financial reporting and audit requests with well-organized documentation

Partner Billing & Reporting

• Own invoicing, cash application, and partner reporting processes
• Ensure billing and reporting align with contractual terms and timelines
• Track and manage milestone billing, cost-sharing arrangements, and other variable components

Process Improvement & Systems

• Build and refine scalable processes for managing revenue
• Partner with systems teams to operationalize revenue workflows in ERP systems (e.g., NetSuite)
• Develop templates, trackers, and documentation to improve efficiency and reduce risk

Cross-Functional Coordination

• Partner closely with legal, FP&A, business development, and scientific teams to ensure alignment between contracts and execution
• Proactively identify gaps or ambiguities in agreements that could impact revenue operations

What You’ll Need to Succeed

• 6+ years of experience in accounting, with exposure to revenue recognition
• Strong working knowledge of ASC 606 and ability to apply it in practice
• Experience operationalizing revenue processes (billing, revenue tracking, reconciliations)
• Experience reviewing contracts and translating terms into accounting workflows
• Strong attention to detail and ability to manage multiple agreements simultaneously
• Excellent organizational and cross-functional communication skills

Bonus Points For

• Experience in biotech, life sciences, or deep tech environments
• Familiarity with collaboration agreements, licensing, milestone-based revenue, or cost-sharing arrangements
• Experience with NetSuite or similar ERP systems
• CPA
• Ability to operate in a fast-paced, evolving environment

Your Impact at LILA

The Staff/Principal DevOps Engineer will drive the design, implementation, and optimization of our infrastructure and delivery platforms. This role bridges platform engineering, site reliability, and DevOps practices, building scalable, automated systems that enable fast, reliable software delivery across cloud and Kubernetes environments. You will collaborate with software engineers, lab scientists, and ML engineers to build infrastructure that powers automated scientific analysis, experiment orchestration, and more.

What You'll Be Building

• Build Kubernetes-based infrastructure supporting scientific services, ML pipelines, and platform workloads; including production hardening, RBAC, network policies, and Pod Security Standards
• CI/CD pipelines with GitHub Actions/GitLab CI implementing best practices: build attestations, SBOM generation, dependency scanning, and container image hardening
• Infrastructure-as-code with Terraform and Helm; policy-as-code guardrails (OPA/Kyverno/Checkov) with drift detection
• AWS cloud infrastructure: EKS clusters, IAM least privilege, VPC/PrivateLink networking, KMS/Secrets Manager, ECR, S3, and centralized logging/monitoring
• Platform tooling to streamline deployment, observability, and developer workflows, enabling self-service with secure defaults
• Reliability engineering: SLOs/SLIs, incident response, capacity planning, and performance optimization throughout the stack
• Software supply chain practices: artifact signing, registry governance and vulnerability management
• QA and testing infrastructure: static analysis and code quality gate enforcement in CI pipelines, automated end-to-end and browser-based regression test suites, ephemeral test environments for PR-based validation, and pre-merge quality checks
• Automation and tooling in Python or Go to improve infrastructure operations and integrate telemetry with observability platforms

What You’ll Need to Succeed

• Expertise in DevOps, SRE, or Platform Engineering in large scale cloud environments
• Expertise in deploying to cloud environments (AWS, GCP, etc) using infrastructure-as-code (Terraform, Helm) and containerization
• Deep experience with CI/CD systems (GitHub Actions, GitLab CI, or Jenkins) and GitOps practices
• Strong proficiency in Python/scripting languages for automation and tooling
• Strong understanding of Kubernetes operations: deployments, networking, storage, observability, and troubleshooting

Bonus Points For

• Experience with GitOps tools (ArgoCD, Flux)
• SRE practices: observability platforms, chaos engineering, incident management
• Securing ML/AI pipelines (model registries, training clusters, inference gateways)
• Experience in regulated/audit-heavy environments (SOC 2, ISO 27001)
• Supply chain security maturity: SBOMs, image signing, SLSA concepts
• Administering static analysis platforms (custom quality profiles, security hotspot triage) and scaling browser-based test suites across parallel CI environments
• Prior startup/high-growth experience balancing velocity with reliability

Your Impact at LILA

Lila is building a talent-dense, high-agency AI safety team at Lila that will engage all core teams within the organization (science, model training, lab integration, etc) to prepare for risks from scientific superintelligence. We are looking for a Senior or Principal Technical Program Manager to join our AI Research team and serve as a critical operational force behind our AI safety work.

In this role, you will be the connective tissue between our researchers, model development teams, engineering, policy stakeholders, and leadership — translating complex, fast-moving research programs into structured, accountable execution. While not an ML researcher yourself, but you must be genuinely curious about the technical substance of AI safety work, and able to clearly articulate what our efforts are trying to accomplish. The successful candidate will be someone who thrives in ambiguity, communicates exceptionally well across audiences, and knows how to build clarity and momentum in a fast paced and rapidly growing team.

What You'll Be Building

• Serve as the key communication interface between the AI safety team and the research, science and technical teams, effectively communicating complex outcomes and securing necessary resources. Set up the organisational information flows that allow for this communication to happen with speed at scale.
• Drive accountability across distributed, cross-functional teams without relying on direct authority; build consensus through clear communication and sound judgment.
• Implement best practices for rapid experimentation and iteration, facilitating efficient and agile program progression.
• Develop clear documentation and reporting to communicate vision, track progress, and align initiatives with organizational priorities.
• Represent program status and risks accurately and confidently, even when the picture is uncertain or evolving.

What You’ll Need to Succeed

• Bachelor’s or Master’s degree in Computer Science, Engineering, Life Sciences, or a related field.
• 6+ years of program or project management experience in the technology or life sciences field.
• Proven experience in program management, leading cross-functional teams and driving programs to successful completion.
• Strong analytical and problem-solving skills, with the ability to turn technical requirements into actionable program roadmaps.
• Exceptional written and verbal communication skills; a track record of producing executive-quality documents, roadmaps, and updates that drive decisions.

Bonus Points For

• Direct experience in AI/ML research or product organizations, ideally in a program management or research operations capacity.
• Working familiarity with AI safety concepts — alignment, red-teaming, evaluations, responsible scaling — sufficient to engage credibly with researchers and ask good questions.
• Experience managing programs that span safety, compliance, or governance workstreams, particularly in the context of model development and deployment.
• Enthusiastic about emerging technologies and experienced in driving rapid experimentation and program iteration.

About the Role

We are seeking a detail-oriented and commercially driven Manager of Business Development Operations to own end-to-end BD execution across our IBD, broader GI, and hepatology portfolio. This is a highly cross-functional role that sits at the intersection of commercial strategy, site operations, and sponsor partnerships. Reporting to the Director of Business Development, you will serve as the primary internal point of contact for new contracts and play a critical role in ensuring seamless execution from lead to signed study. You will own the processes, metrics, and relationships that keep our BD pipeline moving — and ultimately help bring new therapies to patients faster.

Responsibilities

• Own the end-to-end, internal business development process from initial sponsor engagement through contract execution, serving as the single internal touchpoint for new contracts
• Lead the cross-functional scoping and pricing process for new study opportunities
• Keep the business development pipeline organized and visible by maintaining up-to-date reporting on where each opportunity stands
• Support the Director of Business Development in preparing for key sponsor interactions, including developing pitches and proposals, building conference materials, and ensuring the team shows up well-prepared for high-stakes meetings
• Continuously identify opportunities to streamline and improve the business development process to accelerate deal pull-through and reduce time to contract close

Required Qualifications

• 4–7+ years of experience in life sciences, clinical trials, business development, or enterprise partnerships
• Experience managing end-to-end commercial processes, from scoping and pricing through contract execution
• Strong cross-functional collaborator with a track record of working effectively across clinical, operations, and legal teams
• Highly organized with strong attention to detail and ability to manage multiple deals and workstreams simultaneously
• Excellent communication and relationship management skills
• Comfortable working in a fast-paced, high-growth environment with competing priorities

Preferred Qualifications

• Experience in gastroenterology, hepatology, or adjacent therapeutic areas
• Deep understanding of the clinical trials landscape
  • Advanced degree in healthcare or business (MBA, MPH, or equivalent)

As the Clinical Operations Manager, you will report to the VP, Growth and work closely with our Clinical Research and Life Sciences teams to integrate Iterative Health (IH) services and AI solutions at clinical research sites throughout the US. This external-facing role will require strong communication, customer engagement and deep expertise in clinical research, in addition to a strong strategic skill set. You will engage with partners such as sponsors, CROs and key sites to drive executive operational alignment, providing strategic recommendations both internally and externally with a focus on improving research operations focused on biological sample collections trials. You’ll also be working directly with your portfolio of sites to deliver day-to-day support that encourages research best practices, drives the adoption of IH services and products, and ensures our sites achieve their research goals. 

Key Responsibilities: 

• Own end-to-end clinical research operations for biological sample collections trials, serving as the primary accountable party for trial execution quality and sponsor satisfaction outcomes
• Build and manage DCT (decentralized clinical trial) vendor relationships, including performance management, metrics tracking, and oversight to ensure biological sample collections trial delivery
• Own the information flow between sites and sponsors - including internal study education, site engagement protocols, and issue escalation pathways
• Serve as leading sponsor-facing owner for active studies - leading alliance management meetings by providing study updates, reviewing metrics, discussing site accomplishments and ongoing issues, and gathering information to relay to site-based staff, driving sponsor satisfaction, and owning escalation resolution
• Drive direct QC enforcement with site CRCs/staff, including data quality expectations-setting and direct communication on compliance gaps
• Own site performance improvement through metrics, change management, and direct intervention - proactively identifying and resolving performance gaps before sponsor escalation
• Demonstrate advanced knowledge of clinical research processes and tools, such as CTMS, pre-screening, and/or feasibility, and enhance these processes and outputs to effectively support our sites or internal teams. 
• Serve as a subject matter expert on clinical research workflows, in line with specific requirements of each protocol, optimized with Iterative Health (IH) services and AI solutions
• Support and lead weekly meetings with site-based staff to review enrollment progress, address operational issues, and provide guidance for performance improvement.
• Manage customer relationships with a high degree of professionalism and expertise ensuring timely responses, escalations of site issues, and building trust needed to help sites achieve IH goals
• Leverage IH solutions and services to help build best practice research sites, accelerate clinical trials, and build capacity at IH sites to execute high-quality clinical trials. 
• Deliver customized training for different clinical research user groups and devise process maps/workflows, tools, and techniques to help sites incorporate IH services
• Travel to customer sites to support study site activation, drive patient screening, and standby support for randomization activities 
• Collect, analyze, and communicate the voice of IH customer successes, concerns, and product adoption issues/competency gaps and collaborate with IH cross-functional teams to design and deliver solutions 

Required skills: 

• BS/BA or higher degree. 
• Minimum 4 years of clinical research coordinator experience
• At least 8 years of experience with biological sample collection trials and/or phase 2-4 pharma-sponsored clinical trials, including study start-up, CDA, feasibility, regulatory/standard operating procedures, study protocols, and regulations governing clinical research 
• Experience coordinating, evaluating, and following patients’ participation through clinical trials.
• Fluent in the use of Microsoft Office/Google Apps products. 
• Ability to navigate ambiguity and willingness to be flexible/adapt to changing work environments. 
• Desire to work with new tools and technology
• Ability to manage multiple projects, meet deadlines, and adjust priorities appropriately.
• Willingness to travel to customer sites (~30%) 

Preferred skills: 

• 5+ years as a Clinical Research Coordinator (CRC) working with biological sample collections trials or equivalent experience
• Experience with CTMS systems - preferably RealTime, Clinical Conductor, or CRIO

About the Role

We are seeking a motivated and detail-oriented Clinical Research Finance Specialist to join our growing Finance team. This role partners closely with the Finance Manager to support end-to-end accounts receivable operations across sponsor-funded clinical studies and internal research sites.

You will own core transactional AR workflows, including monitoring sponsor and site-level accounts, supporting timely collections, posting cash in RealTime CTMS, and assisting with invoicing as needed. This role requires close collaboration with internal teams, research sites, and sponsors and CROs to ensure accurate billing, timely cash application, and prompt resolution of outstanding balances.

The ideal candidate thrives in a fast-paced clinical research environment and enjoys balancing hands-on execution with cross-functional collaboration and continuous process improvement.

Key Responsibilities

• Support day-to-day accounts receivable operations, including monitoring sponsor and site-level balances and assisting with timely collections
• Reconcile study-level balances and payment activity, identifying discrepancies and partnering with stakeholders to resolve issues
• Accurately post cash receipts and payment details in RealTime CTMS and related financial systems
• Prepare and issue invoices for study activities and services in coordination with sponsor communications and internal teams
• Communicate professionally with sponsors and CROs regarding billing questions, payment status, and outstanding balances
• Assist in the preparation of AR aging schedules, financial summaries, and internal reporting
• Support audits and financial reviews related to accounts receivable and billing activity
• Collaborate cross-functionally with Clinical Operations, Site Finance, and Accounting to clarify billing terms and deliverables
• Contribute to ongoing process improvements to enhance AR efficiency, accuracy, and visibility
• Provide general finance support as needed to ensure smooth AR operations

Required Qualifications

• Bachelor’s degree in Finance, Accounting, Business, or a related field (or equivalent practical experience)
• 2+ years of experience in accounts receivable, billing, or finance operations
• Strong proficiency in Microsoft Excel, including data analysis and reporting
• High attention to detail with the ability to manage multiple priorities and deadlines
• Excellent written and verbal communication skills, with a professional approach to external stakeholders

Preferred Qualifications 

• Experience with RealTime CTMS or similar clinical trial management and billing systems
• Background in healthcare, clinical research, or multi-site organizations
• Familiarity with sponsor contracts, clinical trial invoicing, or study-level financial reconciliation

We are seeking an energetic, highly organized and detail-oriented individual to fill a full-time, Payroll Specialist role. The ideal candidate is an enthusiastic self-starter who is motivated to set and  achieve goals and take initiative within the workplace. They are organized, professional  and demonstrate excellent attention to detail. The successful candidate will be critical in reducing manual processing risks, ensuring regulatory compliance, systems automatizations and day-to-day payroll operations. This position will give you the opportunity  to grow your payroll and accounting knowledge and experience.  This role plays a key part in ensuring the accuracy and efficiency of our financial operations and will support broader financial reporting and compliance initiatives.

Key Responsibilities

• Process and finalize payroll runs (Semi-Monthly, Bi-Weekly, Weekly, and specialized off-cycle runs) for all employees using our primary payroll platforms, Rippling and ADP.
• Verify all timecards, wage computation, statutory deductions, benefits deductions, garnishments, and employee changes for accuracy and compliance.
• Manage end-to-end processing, including reconciling final payroll previews and submitting funding requests.
• Serve as the primary subject matter expert for payroll and HRIS systems including Rippling, ADP, and BambooHR.

• Prepare payroll-related General Ledger (GL) entries into the NetSuite accounting system, ensuring accurate cost center allocations.
• Reconcile payroll accounts on a monthly basis.
• Monitor and reconcile bank account transactions related to payroll disbursements.

• Ensure timely and accurate processing of all federal, state, and local tax remittances, including quarterly and year-end reporting (W-2s, 1099s, 941a reports).
• Manage new state registrations for employees and quarterly Workers' Compensation (WC) tax reporting.
• Administer 401K contribution processing. 
• Support the annual 401K audit..
• Respond to and resolve employee inquiries regarding pay, deductions, and tax forms, reducing the administrative burden on the Accounting Manager.

Required Qualifications

• Education: Associate’s degree in Accounting, Finance, or a related field; Bachelor’s degree preferred.
• Experience: 2+ years of dedicated payroll processing experience, ideally managing high-frequency (monthly, bi-weekly, weekly) and multi-state payroll.
• System Proficiency: Proven, hands-on expertise with major systems including ADP, Rippling, Fidelity 401K, NetSuite, and advanced Microsoft Excel skills.
• Skills: Exceptional attention to detail, strong analytical and problem-solving skills, and ability to handle confidential information with discretion.

Preferred Qualifications

• Familiarity with ADP, Rippling, Bamboo, NetSuite.
• Professional certification (e.g., Fundamental Payroll Certification (FPC) or Certified Payroll Professional (CPP)).
• WorkDay Experience

Program Manager II, Integrations

About the Role

We are seeking a Program Manager II, Integrations to support the end-to-end integration of acquired companies and new partnerships. This role is responsible for executing integration activities within defined timelines, proactively identifying and resolving blockers, and contributing to the continuous improvement of integration workflows to increase speed, predictability, and impact.

This role requires a strong operator who can manage complex details and cross-functional dependencies day-to-day, while also contributing to systemic process improvements. Working closely with the Senior Program Manager, Integrations, the Program Manager II will develop deep expertise across the integration lifecycle – with a clear growth path toward independently owning and driving end-to-end integrations for single-site acquisitions.

Key Responsibilities

Program Execution & Coordination

• Support the end-to-end M&A integration process, from pre-close planning through post-close execution, managing timelines, dependencies, and risks across multiple concurrent workstreams
• Build and maintain comprehensive project plans detailing integration tasks, milestones, timelines, and responsible parties
• Ensure integration milestones are met within defined SLAs, escalating risks and delays proactively with clear context, impact, and recommended solutions
• Lead recurring integration workstream meetings, ensuring pre-meeting briefings, post-meeting action items, and project plans are continuously updated and shared with relevant stakeholders

Cross-Functional Coordination

• Coordinate across cross-functional partners including clinical operations, regulatory, legal, finance, and commercial teams
• Identify cross-functional integration dependencies and work to alleviate bottlenecks
• Drive alignment and follow-through across stakeholders with differing priorities
• Help teams prioritize tasks across multiple concurrent integration activities

Process Improvement & Documentation

• Identify bottlenecks and inefficiencies in the integration lifecycle using data and operational insights
• Contribute to the development and maintenance of the integration playbook and standardized templates
• Support the standardization of processes and operating rhythms to support scale, with an eye toward automation
• Maintain clear integration documentation and reporting artifacts

Metrics & Reporting

• Maintain and update the integration reporting dashboard for leadership visibility
• Track key performance indicators to measure the success of integration efforts
• Use data to inform prioritization and process improvements

Required Qualifications

• 3–5 years of experience in program management, operations, M&A integration, or project management
• Proven track record of managing complex, cross-functional projects with tight timelines and multiple stakeholders
• Strong execution skills with exceptional attention to detail and organizational ability
• Experience facilitating efficient meetings and ensuring accountability for results
• Excellent written and verbal communication skills, including the ability to simplify complex topics
• High degree of ownership, judgment, and comfort operating independently

Preferred Qualifications

• Experience contributing to or executing acquisition integration projects
• Experience in healthcare technology, clinical research, or life sciences
• Familiarity with change management methodologies
• Experience scaling or maturing operational programs in growing organizations

About the Role

Iterative Health is looking for a Sr Manager, Analytics to be the primary analytics partner to our operations and go-to-market teams. You will own how we define, measure, and improve performance across the business, turning raw data into clear insights that drive smarter decisions and faster execution.

This is a hands-on, high-impact role for someone who loves digging into data, building scalable reporting, and influencing strategy. You’ll work closely with Operations, Sales, and our Finance team to ensure leaders have the metrics and insights they need to grow efficiently.

Responsibilities

Own our metrics

• Define and standardize KPIs across sales, marketing, professional services and product
• Establish trusted definitions and a single source of truth for performance data
• Ensure teams are aligned on what “good” looks like and how it’s measured

Deliver insights that drive decisions

• Conduct deep-dive and ad hoc analyses to identify trends, bottlenecks, and growth opportunities
• Translate business questions into structured analyses and actionable recommendations
• Support planning, prioritization, and leadership reviews with clear data storytelling

Build scalable reporting

• Design and maintain dashboards and automated reporting in SQL and BI tools
• Replace manual spreadsheets with reliable, self-serve analytics
• Make data accessible and easy to use for non-technical stakeholders

Forecast and model performance

• Develop forecasts and models for sales performance, capacity planning, and operational targets
• Run scenario analyses to evaluate trade-offs and risks
  
  

Partner on data infrastructure

• Work closely with the Business Intelligence team on reporting architecture and analytics tooling
• Collaborate with Finance, who owns the Enterprise Data Warehouse, to ensure clean and reliable upstream data
• Improve data quality, documentation, and governance practices

Raise the bar on analytics

• Mentor teammates on best practices and enable self-serve reporting
• Champion a metrics-driven culture across the organization

What we’re looking for

Required Qualifications

• 6–9+ years in data analytics, business intelligence, or similar roles in a fast-paced or high-growth environment
• Advanced SQL and comfort working directly with large, messy datasets
• Strong experience with BI tools (Power BI, Looker, Tableau, etc.)
• Proven track record building dashboards, defining KPIs, and automating reporting
• Experience translating ambiguous business problems into structured analyses
• Excellent communication skills - able to influence leaders and explain insights simply
• Highly self-directed and comfortable owning problems end-to-end
  
  

Preferred Qualifications

• Experience with Salesforce or sales/revenue analytics
• Python or R for advanced analysis
• Experience working with modern data warehouses (Snowflake, BigQuery, Redshift)

About the role

As the Manager of Facilities & Engineering and Site Operations Lead for the Cambridge site, you will serve as a site Facilities and Engineering leader responsible for driving strategic facility, asset, and site wide operational programs across two locations. You will provide clear direction, influence decisions, and ensure that all facilities, engineering, and teams work cohesively to support day-to-day operations and corporate objectives.

In partnership with the Facilities and Engineering leadership, you will translate organizational priorities into actionable plans, communicate expectations clearly to stakeholders, and cultivate a high trust, high performance environment. This role requires a leader who is proactive, systems minded, and able to align cross functional teams and external partners around shared goals.

What you’ll do

Operational Leadership

• Lead the development and execution of facility, equipment, and operational strategies that advance site readiness, reliability, safety, compliance, and efficiency.
• Drive short and long range planning for the site’s assets, capital improvements, the maintenance/calibration program, and operational continuity.
• Oversee implementation and continuous improvement of programs covering the management of facilities, equipment maintenance and calibration, building systems and utilities, and project management and execution.
• Lead the development and execution of Facilities and Engineering initiatives to support scientific objectives and corporate strategies.
• Participate with leadership in the development of site Facilities and Engineering budgets, and management of established budgets.

Communication and Execution

• Manage day to day operations for both facilities, ensuring that work is properly prioritized and performed in accordance with business, safety, and quality requirements.
• Establish and monitor operational metrics, customer service standards, and performance indicators to promote transparency and continuous improvement.
• Act as the primary point of contact for site Facilities and Engineering, ensuring clear, timely, and solution oriented and transparent communication.
• Collaborate on contract negotiations, vendor selection, and provide vendor oversight to ensure operational reliability and cost effective, compliant service delivery.
• Collaborate with other operations functions within Sana (Site Lead, IT, Procurement, Facilities & Engineering, People, Legal) to drive solutions for Cambridge site needs.
• Build strong relationships with internal partners, external vendors, and contractors to ensure business and quality requirements are fulfilled.
• Partner with Environmental Health and Safety and Business Leaders to support emergency response plans and events.
• Facilitate site wide messaging around operational changes, space planning, project impacts, and service disruptions.
• Oversee facility and equipment service contract administration, planning and scheduling, and procurement of parts, tools, and equipment.

What we’re looking for

• Bachelor’s degree in engineering or related field.
• 7+ years of experience leading facilities, engineering, or lab operations in biotechnology or related industries.
• Demonstrated ability to influence stakeholders, and lead through change in a fast-paced, dynamic environment.
• Exceptional communication skills—able to simplify complex operational problems to drive clarity and align diverse audiences around shared objectives.
• Proven ability to manage competing priorities while maintaining strong partnerships across scientific, operational, quality, and business teams.
• Deep understanding of facility and utility systems (HVAC, gases, DI water, electrical, etc.), and asset lifecycle management in GxP environments.
• Sound judgment and troubleshooting skills and the capacity to resolve diverse problems effectively and in alignment with business needs
• Experience managing preventive maintenance and calibration programs, capital projects, vendor relationships, and cross‑site operational systems.
• Strong analytical and problem‑solving capabilities, with the ability to provide fit for purpose solutions.
• Embodies Sana’s core values: Lead from every seat, Thrive as a team, Make it happen.
• Demonstrates sound judgment, proactive thinking, and a commitment to a safe, compliant, and collaborative workplace.

What you should know

• The base pay range for this position at commencement of employment is expected to be between $140,000 and $160,000/year; however, base pay offered may vary depending on multiple individualized factors, including market location, job-related knowledge, skills, and experience 

Who We Are

Flagship Pioneering is a biotechnology company that invents and builds platform companies that change the world. We bring together the greatest scientific minds with entrepreneurial company builders and assemble the capital to allow them to take courageous leaps. Those big leaps in human health and sustainability exponentially accelerate scientific progress in areas ranging from cancer detection and treatment to nature-positive agriculture.  

What sets Flagship apart is our ability to advance biotechnology by uniting life science innovation, company creation, and capital investment under one roof in a way that is largely without precedent. Our scientific founders, entrepreneurial leaders, and professional capital managers are each aligned around an institutionalized process that enables us to innovate and transform for the benefit of people and planet.  

Many of the companies Flagship has founded have addressed humanity’s most urgent challenges: vaccinating billions of people against COVID-19, curing intractable diseases, improving human health, preempting illness, and feeding the world by improving the resiliency and sustainability of agriculture. 

Flagship has been recognized twice on FORTUNE’s “Change the World” list, an annual ranking of companies that have made a positive social and environmental impact through activities that are part of their core business strategies, and has been twice named to Fast Company’s annual list of the World’s Most Innovative Companies.

Role Summary:

The Director, IT Service Delivery & Operations is a senior leadership role operating at the intersection of strategy and execution. This position serves as the critical bridge between IT leadership priorities and operational delivery — translating strategic direction into actionable plans and ensuring execution remains aligned with organizational goals.

This role does not directly execute service delivery; it enables those who do. The Director establishes governance frameworks, defines performance expectations, and provides the structure, visibility, and accountability required for delivery teams to succeed. The role also leads initiative implementation through structured hypercare, ensuring successful adoption and transition into steady-state operations.

Working closely with the Sr. Director of IT Service Delivery, this leader co-shapes the service roadmap, advances ITIL 4 service management maturity, and builds the operational discipline required to scale IT services across Flagship and its portfolio.

Role Context

This role operates in close partnership with two key functions:

• Director, IT Service Delivery – owns execution of the service model, delivery teams, and stakeholder relationships.
• Service Excellence Manager – owns process design, reporting, ITSM practices, and operational coordination.

The Director, IT Service Delivery & Operations defines the governance, accountability, and performance frameworks within which these functions operate — enabling consistent, high-quality execution without owning day-to-day delivery.

Key Responsibilities

1. Strategy-to-Execution Leadership

• Translate IT strategy into structured implementation plans with clear milestones, ownership, and success metrics.
• Partner on roadmap planning, prioritization, and sequencing of initiatives.
• Lead initiatives through hypercare, ensuring adoption, issue resolution, and smooth transition to steady state.
• Provide change leadership to delivery teams — setting expectations, removing barriers, and ensuring clarity.
• Maintain visibility into initiative progress; escalate risks, blockers, and decisions proactively.

2. Governance & Performance Oversight

• Define and govern SLAs, KPIs, OLAs, and reporting frameworks aligned to ITIL 4 principles.
• Interpret service performance data to identify systemic issues and improvement opportunities.
• Own the Continual Service Improvement (CSI) program, setting priorities and sponsoring initiatives.
• Conduct regular operating reviews; provide coaching and accountability across functions.
• Ensure customer experience metrics (e.g., CSAT/NPS) are measured and acted upon.

3. IT Asset Management (ITAM) Governance

• Establish and govern the ITAM program, including policies, lifecycle standards, and data integrity.
• Define CMDB governance and accountability for accuracy and completeness.
• Guide asset lifecycle processes (procurement, deployment, refresh, disposition).
• Leverage asset data to inform investment, lifecycle planning, and cost optimization.
• Partner with Finance and Procurement to align asset strategy with budgets and forecasts.

4. Vendor Governance & Performance

• Define vendor governance frameworks, onboarding standards, and performance expectations.
• Establish and enforce SLAs/KPIs within vendor contracts.
• Lead vendor performance reviews and drive accountability through data-backed insights.
• Partner with Legal and Procurement on renewals, negotiations, and performance remediation.

5. ITIL 4 & ITSM Maturity

• Assess current ITSM capabilities and define a multi-year ITIL 4 maturity roadmap.
• Sponsor adoption of core practices (Incident, Problem, Change, Service Request, Service Level).
• Establish governance forums (e.g., CAB, Problem Review Board) with clear decision structures.
• Govern ITSM platforms to ensure alignment with processes and continuous optimization.
• Track and report on service management maturity and performance trends.

6. Team Enablement & Leadership

• Define clear roles, responsibilities, and accountability structures across service delivery functions.
• Coach and develop team leaders, fostering a culture of accountability and continuous improvement.
• Build organizational capability, talent pipelines, and succession plans.
• Promote a culture grounded in customer focus, operational rigor, and data-driven decision-making.

7. Strategic Partnership

• Partner with IT leadership to co-develop strategy, roadmaps, and capability plans.
• Represent the service delivery function in leadership forums and executive discussions.
• Contribute to business cases, budget planning, and investment decisions.
• Build strong relationships with stakeholders, IT peers, and strategic vendors.
• Identify risks and opportunities, providing actionable recommendations to leadership.

Qualifications

Required

• 10+ years of IT experience, including 5+ years in service delivery, operations, or ITSM leadership.
• Demonstrated ability to lead through governance and enablement rather than direct execution.
• Proven experience translating strategy into execution and leading initiatives through change.
• Strong background in ITIL-aligned service management and ITSM program development.
• Experience designing and governing ITAM/CMDB programs.
• Vendor management experience with performance accountability and contract alignment.
• Strong analytical and data interpretation skills.
• ITIL 4 Foundation certification (advanced certifications preferred).
• Experience governing enterprise ITSM platforms.
• Excellent communication skills across technical and executive audiences.

Preferred

• Experience in life sciences, biotech, or research environments.
• Familiarity with ITAM/HAM tooling within ITSM platforms.
• PMP or equivalent certification.
• Experience with IT financial management and budget planning.
• Experience in matrixed or multi-entity organizations.

Leadership Competencies

• Bridge Leadership: Aligns strategy with execution seamlessly.
• Enabling Leadership: Builds capability and empowers teams to perform.
• Structural Thinking: Designs scalable governance and operating models.
• Customer Focus: Drives accountability for service experience outcomes.
• Data-Driven: Uses insights to guide decisions and improvements.
• Strategic Partnership: Contributes meaningfully at the leadership level.
• Executive Presence: Communicates with clarity and credibility.
• Builder Mindset: Thrives in ambiguity and creates structure.

We are an equal opportunity employer. All qualified applicants will be considered for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, disability, protected veteran status, or any other characteristic protected by law. 

We recognize that great candidates often bring unique strengths without fulfilling every qualification. If you have some of the experience listed above but not all, please apply anyway. We are dedicated to building diverse and inclusive teams and look forward to learning more about your background and interest in Flagship. 

Recruitment & Staffing Agencies: Flagship Pioneering and its affiliated Flagship Lab companies (collectively, “FSP”) do not accept unsolicited resumes from any source other than candidates. The submission of unsolicited resumes by recruitment or staffing agencies to FSP or its employees is strictly prohibited unless contacted directly by Flagship Pioneering’s internal Talent Acquisition team. Any resume submitted by an agency in the absence of a signed agreement will automatically become the property of FSP, and FSP will not owe any referral or other fees with respect thereto. 

#LI-NM1 

The salary range for this role is $172,000 - $236,500. Compensation for the role will depend on a number of factors, including a candidate’s qualifications, skills, competencies, and experience. Flagship Pioneering currently offers healthcare coverage, annual incentive program, retirement benefits and a broad range of other benefits. Compensation and benefits information is based on Flagship Pioneering's good faith estimate as of the date of publication and may be modified in the future.

Flagship Pioneering is a bioplatform innovation company that invents and builds platform companies that change the world. We bring together the greatest scientific minds with entrepreneurial company builders and assemble the capital to allow them to take courageous leaps. Those big leaps in human health and sustainability exponentially accelerate scientific progress in areas ranging from cancer detection and treatment to nature-positive agriculture.   

 What sets Flagship apart is our ability to advance biotechnology by uniting life science innovation, company creation, and capital investment under one roof in a way that is largely without precedent. Our scientific founders, entrepreneurial leaders, and professional capital managers are each aligned around an institutionalized process that enables us to innovate and transform for the benefit of people and planet.   

Many of the companies Flagship has founded have addressed humanity’s most urgent challenges: vaccinating billions of people against COVID-19, curing intractable diseases, improving human health, preempting illness, and feeding the world by improving the resiliency and sustainability of agriculture.  

Flagship has been recognized twice on FORTUNE’s “Change the World” list, an annual ranking of companies that have made a positive social and environmental impact through activities that are part of their core business strategies, and has been twice named to Fast Company’s annual list of the World’s Most Innovative Companies. 

Position Overview: 

Flagship Pioneering is seeking a Senior Manager, HR Operations & Systems to own and evolve our HR systems ecosystem, with primary responsibility for UKG and broad oversight of platforms including Greenhouse and other HR technologies. This role will drive day-to-day administration, governance, integrations, and future-state strategy of HR systems to ensure compliance, enable scalable service delivery, strengthen data integrity, and support a seamless employee experience across the lifecycle. Reporting to the Associate Director, HR Operations & Analytics, this leader will partner closely with HR, Legal, Payroll, Finance, and Enterprise Applications / IT to design system-enabled HR operations that are scalable, well-governed, and built for growth. 

Role Summary 

The Senior Manager, HR Operations & Systems will serve as the business owner for Flagship’s HR systems ecosystem within HR Operations, with primary responsibility for the strategy, administration, optimization, and operational enablement of core HR platforms, including UKG, Greenhouse, and other HR technologies across the employee lifecycle. 

Reporting to the Associate Director, HR Operations & Analytics, this role will partner closely with HR Operations, Talent, Total Rewards, Learning & Culture, Legal, Payroll, Finance, People Analytics, and Enterprise Applications / IT to ensure systems support the HR function in a scalable, compliant, and analytically sound way. 

This leader will help stitch together the HR systems landscape through thoughtful integrations, controls, documentation, and future-state HR tech strategy, while acting as a subject matter expert to IT for implementation and technical design. 

Key Responsibilities 

HR Systems Ownership & Administration 

• Serve as the primary HR business owner for HR systems, with deep ownership of UKG and operational oversight of other HR and talent platforms such as Greenhouse, TalentWall, Crosschq, LinkedIn Recruiter, Pequity, and future tools. 

• Manage day-to-day administration of HR systems, including configuration, permissions, security roles, workflows, testing, issue resolution, release support, and operational documentation. 

• Ensure HR systems are structured and maintained to support scalable service delivery, consistent HR operations, and strong user experience across the employee lifecycle. 

• Maintain system standards, field logic, process flows, and governance documentation to improve consistency and reduce operational ambiguity. 

Systems Architecture, Process Design & Integrations 

• Architect HR systems and processes from an operational perspective, ensuring systems support onboarding, transfers, promotions, offboarding, compliance requirements, and service delivery across the employee lifecycle. 

• Design and optimize integrations across the HR systems landscape, including key connections such as UKG-ADP and Greenhouse-UKG, to improve data flow, reduce manual work, and strengthen downstream reporting and controls. 

• Partner with Enterprise Applications / IT to define technical requirements, integration priorities, testing strategy, and implementation needs; serve as the HR SME for system changes and implementations while IT owns technical implementation and vendor management. 

• Be sufficiently hands-on and technically fluent to configure systems directly where appropriate and to effectively guide or direct technical work when builds are completed by IT or other partners. 

• Identify automation opportunities and future-state improvements across HR systems to improve scalability, reduce friction, and support evolving business needs. 

Compliance, Controls & Governance 

• Partner with HR Operations teammates, Legal, and other stakeholders to ensure systems are designed and configured to enable compliance, controls, audit readiness, and consistent execution of HR processes. 

• Manage system-enabled governance, including permissions, process controls, documentation logic, policy acknowledgement workflows, and audit-supporting records. 

• Help ensure systems support compliance execution across key areas such as documentation completeness, training administration, process controls, and employee record quality. 

• Support the creation of scalable, system-enabled HR ways of working by translating process requirements into governed workflows and operational logic. 

Analytics Enablement & Data Integrity 

• Partner closely with the People Analytics Manager to ensure HR systems are structured to support reliable reporting, meaningful analytics, and consistent data definitions. 

• Improve data integrity across systems by aligning field design, ownership, process inputs, and integrations to reduce discrepancies and improve trust in people data. 

• Ensure systems are built with analytics needs in mind, and conversely, help refine systems based on reporting and data-quality insights. 

• Support the broader HR function in strengthening compliance intelligence, scalable service delivery, and experience optimization through better system design and cleaner data. 

Cross-Functional Partnership & Change Enablement 

• Build strong working relationships across HR, IT, Payroll, Finance, Legal, and other G&A partners to align systems strategy and operational delivery with business needs. 

• Support change enablement through documentation, process clarity, and partnership with HR Operations and other HR team members; formal training delivery is not a core responsibility, but this role will help ensure systems and documentation are set up for successful adoption. 

• Contribute to future-state HR tech strategy, including evaluation of system opportunities and support for upcoming initiatives. 

What Success Looks Like 

• HRIS and the broader HR systems landscape are well-governed, well-documented, and operationally effective. 

• Core employee lifecycle processes are increasingly system-enabled, scalable, and aligned across HR and cross-functional partners. 

• Permissions, controls, and integrations support stronger compliance execution and audit readiness. 

• HR data is consistent, reliable, and usable across all company systems and platforms. 

• The HR team and business partners experience smoother workflows, less manual work, and clearer operational processes. 

• Flagship’s HR tech ecosystem is positioned for future growth, automation, and stronger decision support. 

Qualifications 

• Strong hands-on experience with enterprise HRIS administration and configuration; UKG experience strongly preferred, though deep equivalent HRIS experience may be considered. 

• Experience owning or supporting enterprise HR systems across multiple HR process areas. 

• Experience designing, managing, or supporting integrations between HRIS, ATS, payroll, and other people systems. 

• Strong understanding of how systems support employee lifecycle operations, compliance controls, and scalable service delivery. 

• Experience partnering closely with Enterprise Applications / IT teams on technical requirements, integrations, permissions, and implementation planning. 

• Strong judgment and ability to manage confidential employee and organizational data responsibly. 

• Strong written documentation and process-design skills. 

• Proven track record of independently driving operational improvements and cross-functional initiatives. 

At Flagship, we recognize there is no perfect candidate. If you have some of the experience listed above but not all, please apply anyway. Experience comes in many forms, skills are transferable, and passion goes a long way. We are dedicated to building diverse and inclusive teams and look forward to learning more about your unique background.

Recruitment & Staffing Agencies:  Flagship Pioneering and its affiliated Flagship Lab companies (collectively, “FSP”) do not accept unsolicited resumes from any source other than candidates.  The submission of unsolicited resumes by recruitment or staffing agencies to FSP or its employees is strictly prohibited unless contacted directly by Flagship Pioneering’s internal Talent Acquisition team.   Any resume submitted by an agency in the absence of a signed agreement will automatically become the property of FSP, and FSP will not owe any referral or other fees with respect thereto.

#LI-NM1

The salary range for this role is $128,000 - $176,000. Compensation for the role will depend on a number of factors, including a candidate’s qualifications, skills, competencies, and experience. Flagship Pioneering currently offers healthcare coverage, annual incentive program, retirement benefits and a broad range of other benefits. Compensation and benefits information is based on Flagship Pioneering's good faith estimate as of the date of publication and may be modified in the future.

Commercial Auto Underwriting Specialist

The ​Commercial Auto Underwriting Specialist - Auto​ is responsible for the underwriting integrity of the Auto portfolio.  They are a technical lead for Auto underwriters and are responsible for underwriting referrals, providing training specific to Fleet & Garage underwriting, mentoring underwriters and the maintenance and updates of the Commercial wordings and guidelines.

What you will do: ​

• The Commercial Auto Specialist will be a key contributor in the IRCA Quality program for brokers, and underwriters, including the creation of TFR questionnaires, file selection processes, reporting format
• They will support the review and updates of existing underwriting manuals, process documents and authorities so that it aligns to the new IRCA Quality program.
• ​​​The Commercial Auto Specialist is responsible for the Technical File Reviews (TFR’s) and Focused audits (QAR’s) of the IRCA & Fleet underwriters including selection of files for audit, delivering results and coaching on areas improvement in conjunction with the Underwriting Excellence Manager.
• ​Collects trends from all audits and engages the appropriate business areas to develop solutions to close gaps in underwriting rules, training, guidelines and processing instructions.​​
• ​​The Commercial Auto Specialist will support training and mentoring of the IRCA & Fleet underwriters on technical underwriting knowledge. This includes formal training as well as individual mentorships.
• The Commercial Auto Specialist will support the determination of training needs, developing training content and ensuring the training is delivered consistently.
• The Commercial Auto Specialist will contribute to the maintenance of the Commercial Auto underwriting guidelines. They will propose updates and additions as needed using audits and training as input.
• The Commercial Auto Specialist may assist in interpretation of Auto wordings as necessary to support Claims and Underwriting departments.
• Will assist the Manager, Underwriting Excellence with the annual Commercial Auto Underwriting Authority cascade, including recommending changes based on results of TFR’s.
• Will support the investigation and response to any Ombudsman complaints.
• Will support the Product and Pricing teams, as necessary, on any IRCA FSRA filings
• Support internal and external audit requests and implementation of any resultant actions

What you will need to succeed:

• Post Secondary Education
• CIP designation is required, FCIP, CRM is an asset
• 10+ years Commercial Auto underwriting experience
• Underwriting proficiency in IRCA, Fleet and Garage Auto lines of business
• Experience in auditing and delivering audit results
• Experience in delivering technical underwriting training
• Deep understanding of auto regulations and products
• Experience of policy systems and standard operating processes

Required Skills:

• Strategic focus 
• Agility
• Critical Judgement and Decision Making
• Effective Communication
• Business Acumen
• Understanding of Underwriting Risk & Compliance
• Underwriting Process and Pricing
• Knowledge of Insurance Products

Location: Cambridge or Toronto- This is a hybrid work model and requires the individual to work in office on Tuesday’s and Thursday’s.

The expected base salary range for this position is $67,000.00 - $117,000.00. Depending on your relevant experience, skills, qualifications, market conditions and business needs, base compensation may vary. You have the potential to earn more through Gore Mutual’s discretionary bonus program which gives you an opportunity to increase your total compensation, provided the business meets its performance targets and you meet your individual goals.

Please note: This range reflects the expected base salary for this role but may not represent the full compensation range for all experience and skill levels. During the recruitment process, we will discuss and consider how your unique qualifications align with the broader range for this position.

Gore Mutual is proud to offer a comprehensive total rewards package which includes extended health and dental benefits, disability insurance, retirement plan matching, paid time off, recognition and perk programs.

#INDHP

#LI-HYB

Company overview:

Flagship Labs 109, Inc. (FL109) is a privately held, early-stage technology company pioneering the use of artificial intelligence, physics and hardware to transform the way we see biology. FL109 was conceived by Flagship Pioneering, which brings the courage, long-term vision, and resources needed to realize unreasonable results. Become part of our mission-driven team and help envision the future of science.

About the Role

The Director of Sales will be responsible for driving customer acquisition, building strategic partnerships, and delivering revenue growth across our VaaS, SaaS, and platform offerings.

This is a hands-on leadership role for a commercially fluent structural biologist or technical sales leader who can operate as both strategist and executor. You will own a defined bookings target, lead end-to-end customer engagement, and act as the commercial “mini-CEO” for client relationships.

In addition to revenue ownership, you will shape FL109’s market development and outreach strategy, from identifying and cultivating prospective customers to leading participation in key industry events and creating high-impact content that builds awareness and engagement.

This is a builder role: best suited for a commercially fluent leader who thrives on creating structure, establishing customer relationships, and developing scalable business systems in an emerging market.

Key Responsibilities

Revenue & Commercial Ownership

• Own and exceed annual bookings and revenue targets for FL109’s commercial offerings.
• Build and manage a qualified pipeline from prospecting through close, leveraging CRM data to ensure forecast accuracy.
• Hold pricing and commercial terms authority within defined guardrails; manage forecasts and deal reviews with leadership.
• Negotiate and structure agreements that create long-term value for customers and for FL109.
• Partner with Finance and Operations to align delivery plans with revenue recognition and margin goals.
• Report regularly on pipeline health, deal progress, and revenue performance to leadership.

Customer Acquisition & Partnership Development

• Identify, engage, and nurture new customers across pharma, biotech, and the Flagship ecosystem.
• Develop tailored account strategies to expand adoption and drive repeat business.
• Build and maintain trusted executive-level relationships with customer stakeholders.
• Represent FL109 externally at key meetings, conferences, and industry events.

Market Development & Outreach

• Develop and oversee FL109’s external engagement strategy, including targeted outreach, event participation, and partnership visibility.
• Partner with leadership and external vendors to execute campaigns, manage event logistics, and track lead conversion.
• Develop and maintain a calendar of high-impact scientific and commercial events aligned with FL109’s growth priorities.
• Contribute to content creation and thought leadership efforts that build FL109’s brand presence across industry channels and social media.
• Manage a modest budget for event participation and outbound initiatives, prioritizing efforts with the highest commercial impact.

Customer Insight & Market Feedback

• Capture key learnings from customer and partner engagements to refine FL109’s value proposition and go-to-market approach.
• Collaborate with the Product and AI teams to share structured insights that inform product strategy and prioritization.
• Represent customer perspectives in internal discussions to ensure solutions align with market needs.

Commercial Infrastructure

• Partner with a part-time CRM consultant to finalize implementation, ensure data integrity, and establish effective reporting.
• Own the commercial use and adoption of the CRM system to drive visibility, forecasting accuracy, and pipeline health.
• Define and track key growth metrics and reporting cadence for leadership review.

Cross-Functional Collaboration

• Partner with the Client Project Manager to ensure seamless delivery and high customer satisfaction.
• Contribute to pricing, go-to-market, and commercial strategy discussions.
• Work within established templates and tools for contracting, security documentation, and proposal development, with support from internal and external resources as needed.
• Serve as the internal advocate for customer success and external excellence.

Qualifications

• 8+ years of experience in commercial, BD, or sales leadership within life sciences, platform technologies, or capital equipment markets.
• Proven record of achieving or exceeding multi-million-dollar sales targets in complex technical environments.
• Experience leading cross-functional commercial efforts in a matrixed organization.
• Deep understanding of cryo-EM or adjacent analytical technologies preferred.
• Experience with outreach, event strategy, and business development in scientific or technology-driven markets.
• Strong negotiation, forecasting, and strategic account planning skills.
• Excellent communication and executive-level presentation abilities.
• Builder mindset: resourceful, analytical, and comfortable with ambiguity in early-stage environments.

About Flagship

Flagship Pioneering is a bioplatform innovation company that invents and builds platform companies, each with the potential for multiple products that transform human health or sustainability. Since its launch in 2000, Flagship has originated and fostered more than 100 scientific ventures, resulting in generation of over 500 patents, initiation of over 50 clinical trials for novel therapeutic agents and an aggregate value of more than $90 billion. Many of the companies Flagship has founded have addressed humanity’s most urgent challenges: vaccinating billions of people against COVID-19, curing intractable diseases, improving human health, preempting illness, and feeding the world by improving the resiliency and sustainability of agriculture. Flagship has been recognized twice on FORTUNE’s “Change the World” list, an annual ranking of companies that have made a positive social and environmental impact through activities that are part of their core business strategies and has been twice named to Fast Company’s annual list of the World’s Most Innovative Companies. Learn more about Flagship at www.flagshippioneering.com.

Flagship Pioneering is committed to equal employment opportunity regardless of race, color, ancestry, religion, sex, national origin, sexual orientation, age, citizenship, marital status, disability, gender identity or Veteran status.

At Flagship, we recognize there is no perfect candidate. If you have some of the experience listed above but not all, please apply anyway. Experience comes in many forms, skills are transferable, and passion goes a long way. We are dedicated to building diverse and inclusive teams and look forward to learning more about your unique background.

Recruitment & Staffing Agencies: Flagship Pioneering and its affiliated Flagship Lab companies (collectively, “FSP”) do not accept unsolicited resumes from any source other than candidates. The submission of unsolicited resumes by recruitment or staffing agencies to FSP or its employees is strictly prohibited unless contacted directly by Flagship Pioneering’s internal Talent Acquisition team. Any resume submitted by an agency in the absence of a signed agreement will automatically become the property of FSP, and FSP will not owe any referral or other fees with respect thereto.

The expected base salary range for the role is $100,000 to $140,000, with a target commission of $90,000 to $150,000, for a total on-target range of $230,000 to $290,000 OTE. Actual earnings will vary based on performance. Base salary for the role will depend on a number of factors, including a candidate’s qualifications, skills, competencies, and experience. Commission is earned based on defined performance metrics. Flagship Pioneering currently offers healthcare coverage, retirement benefits and a broad range of other benefits. Compensation and benefits information is based on Flagship Pioneering’s good faith estimate as of the date of publication and may be modified in the future.

Join Cartwheel to help tackle the student mental health crisis!

Cartwheel is an early-stage company building a new kind of mental health program for kids that puts schools at the center. We see our role as supporting school staff who see kids every single day. Instead of going around them, we collaborate with them. This means: 

• Earlier intervention
• Higher student and family engagement in care
• Better coordination among the trusted adults in a student’s life 

Kids shouldn't just aspire to get out of bed and drag themselves to class. They should be able to experience joy. They deserve to envision and build a life they’re excited to live. If you join Cartwheel, you’ll help make this vision a reality for millions of students across the country. We’re backed by top investors including A Street Ventures, Menlo Ventures, Reach Capital, General Catalyst, BoxGroup, and Able Partners, and we're looking for mission-driven teammates to join our team.

ABOUT THE ROLE

In 3 years, Cartwheel has grown to serve more than 325 school districts in 16 states, making us the nation’s largest mental health provider that collaborates with K-12 schools. With billions of dollars in new state and federal investments in youth mental health coming in 2026, we are supplementing our district-level sales motion with statewide partnerships with Governor’s offices, education departments, and health agencies.

As the Enterprise Customer Success Manager, you will be Cartwheel's primary point of contact with the state agency, responsible for turning a signed contract into a high-impact, expanding program. That means building the implementation plan, coordinating execution across Cartwheel's internal teams, keeping agency staff informed and confident, and clearing whatever is in the way of delivering exceptional impact. Throughout the contract period, you’ll partner closely with our Government Relations teams, which will own executive and legislative relationships and the contract renewal process.

Role type: W2, Full-Time, Salaried position
Salary range: $143,000 – $187,000 OTE (10% variable pay included) plus competitive equity package
Location: Remote
Target Start: June 2026

WHAT YOU'LL DO

Own the state agency relationship

• Be the primary Cartwheel contact for agency program directors, behavioral health leads, and operational staff — the people responsible for implementing the partnership. 
• Build a deep understanding of agency priorities, constraints, and decision-making so you can navigate complexity and keep things moving
• Develop and maintain a comprehensive contact map across agency implementers, influencers, and financial buyers — and build productive relationships across each layer
• Lead regular agency check-ins covering progress, milestone tracking, and issue resolution
• Navigate agency political dynamics, policy constraints, and interagency complexity
• Develop success stories as implementation matures to support renewal and expansion

Drive implementation

• Build and own the implementation plan for your state(s): What needs to happen, in what order, by when, and who is responsible
• Develop a district prioritization framework: Where to start, how to sequence expansion, how to pace growth against contract timelines
• Own and track the metrics that matter — utilization, district activation, contract milestone attainment — and surface risks early before they become problems
• Coordinate across internal Cartwheel teams to ensure we meet all of our impact goals and milestones. For example:
• Partner with the Government Relations team on renewal readiness and ensure they have an excellent value story to share with executive and legislative buyers
• Ensure district-level sellers and CSMs are effectively onboarding districts
• Coordinate with Operations to clear compliance, credentialing, and regulatory hurdles that slow implementation down

• Engage state-level professional associations (superintendent associations, state education agencies) to support district activation and strengthen Cartwheel's presence

Keep leadership and the team aligned

• Maintain clear, multi-quarter visibility into contract health and district-level risk
• Report out on contract health to Senior Leadership and share insights on how to improve our approach to state implementations, product innovation, or other key insights
• Identify expansion opportunities (new districts, expanded services, adjacent agency relationships) and surface them to Government Relations and internal teams to pursue

WHAT WE’RE LOOKING FOR

Required

• 7–10+ years in customer success, strategic account management, or a closely related post-sale role, with meaningful experience in government or public sector
• You're an exceptional communicator — able to translate operational complexity into clear reporting for agency partners and internal leadership
• You've built trusted relationships with state or government agency staff. Not just executives, but program officers and operational leads
• You've managed complex, multi-stakeholder account plans and can connect the dots between day-to-day execution and long-term contract health
• You understand the revenue implications of implementation decisions and take ownership of retention outcomes
• You can navigate political and bureaucratic dynamics without losing momentum
• You are comfortable interpreting data on your own and communicating insights
• You're highly organized and comfortable building structure in an environment that doesn't have all the answers yet

Preferred

• Experience in K–12 education, healthcare, or direct service businesses
• Familiarity with braided funding models (state contracts, Medicaid, grants, district fees)
• Background working alongside or within Government Relations or public affairs functions
• Experience with state procurement processes and compliance relevant to public sector
• Familiarity with ChurnZero, Gainsight, Salesforce, or HubSpot

Travel

This role requires regular travel — approximately 40% — to support state agency relationships, district engagement, and key implementation milestones, concentrated in your assigned state(s).

Please apply even if you don't meet all of the criteria. If your past experience doesn't perfectly match the job description, but you bring other relevant experience or skills, we'd still love to hear from you. You may be a great fit!

WHY YOU’LL LOVE CARTWHEEL

Our hope is that Cartwheel will be your best career decision! In addition to tackling one of the biggest challenges of our time, at a company well-positioned to do so, you'll have:

• Mission-oriented and inclusive colleagues who will go to bat for you
• Competitive compensation
• Generous PPO medical, vision, and dental/ortho coverage
• Life Insurance
• Generous paid time off, including company closure from Christmas-New Years (12/25-1/1)
• Paid holidays and sick leave
• Paid parental leave
• 401K with employer match
• Meaningful equity ownership stake in Cartwheel
• Flexible and remote role with regular in-person retreats
• Annual learning stipend
• Laptop 

The Manager, IT Service Management (ITSM) is accountable for the end‑to‑end leadership, governance, and continuous improvement of core ITSM processes, including Incident, Problem, Change, Request, Knowledge, and Event Management. This role reports into Director, ITSM & Service Management.

This role serves as both an operational leader and strategic partner, ensuring IT services are reliable, resilient, and aligned with business objectives. The Manager, ITSM leads teams responsible for restoring service during disruptions, preventing recurrence through root cause analysis, enabling controlled change, and driving proactive service improvement through data‑driven insights. The role works extensively across Technology and Business teams, providing enterprise‑level coordination, governance, and executive reporting, and acts as a trusted advisor to senior leadership on service performance, risk, and operational maturity. 

What will you do in this role:

Manage a Team of Incident and Problem Management Specialists

• ​​Provide coaching, mentoring and performance management to direct reports.
• Maintain equitable afterhours and weekend work schedules (Incident response and support coverage).
• Assign work activities, project deliverables, product training, troubleshooting and research assignments etc.   
• ​Facilitate 1:1s, team ceremonies, and skills development aligned to ITSM best practices. 
• ​Ensure appropriate on call, after hours, and weekend coverage for major incidents and critical services. 
• ​Build cross training and succession capability to support service continuity. 

 Responsible for the Development, Implementation and Governance of the core ITSM processes

• Define, implement, and govern ITSM processes in alignment with ITIL and organizational standards. 
• Lead P1/P2 incident response, escalation, communications, and post incident reviews. 
• Oversee Problem Management, including root cause analysis, corrective actions, and trend analysis. 
• Govern Change Management practices, including change lifecycle controls, CAB participation, and risk assessment. 
• Ensure Knowledge Management practices support effective resolution, reuse, and organizational learning. 
• Oversee Event Management practices to enable proactive detection and prevention of service disruptions. 
• Drive continuous improvement to reduce service impact, improve stability, and meet availability targets. 

TSM Strategy, Roadmap, and Governance

• ​​Contribute to and shape the ITSM strategy and multi year roadmap, aligning process maturity improvements with business and technology priorities. 
• ​Participate in IT governance forums, risk reviews, and operational committees. 
• ​Ensure ITSM processes align with enterprise standards for risk management, compliance, audit readiness, and operational resilience. 
• ​Identify improvement opportunities based on performance data, lessons learned, and emerging best practices. 

Cross‑Functional Leadership and Enterprise Coordination

• Act as the primary ITSM liaison with DevOps, Architecture, Infrastructure, Security, Business Continuity, Risk Management, Compliance, PMO, and Process Governance teams. 
• Coordinate cross functional responses during major incidents, changes, and service disruptions. 
• Ensure ITSM processes are integrated with delivery, security, continuity, and risk management practices. 
• Support enterprise initiatives requiring ITSM input, readiness assessments, or operational transition. 

Performance Management, Metrics, and Executive Reporting

• Define, monitor, and report ITSM KPIs and KRIs across all ITSM capabilities. 
• Produce enterprise‑level dashboards and executive reporting covering service performance, risk indicators, trends, and improvement initiatives. 
• Present insights, findings, and recommendations to senior and executive leadership. 
• Use data to drive fact‑based decisions, risk mitigation, and service improvement outcomes. 

What will you need to succeed in this role:

• Community College/Undergraduate degree in Computer Science, Programming
• Certifications: ITIL (required), CMMI DevOps (preferred) 
• 10-15 years' experience in ITSM leadership across multiple process domains 
• 5-7 + years of experience in People Leadership/Management( Team size of 3+)
• 5-7 years' experience in Process Governance (developed, written and implemented process) 
• Strategic planning and roadmap development 
• Executive communication and presentation 
• KPI/KRI definition and dashboard reporting 
• Cross functional and matrix leadership 
• Risk and compliance awareness 
• Data analysis and trend identification 
• ITSM tooling literacy (e.g., ServiceNow) and testing collaboration 

#LI-Hybrid 

The expected base salary range for this position is $118,500 - $168,500. Depending on your relevant experience, skills, qualifications, market conditions and business needs, base compensation may vary. You have the potential to earn more through Gore Mutual’s discretionary bonus program which gives you an opportunity to increase your total compensation, provided the business meets its performance targets and you meet your individual goals.

Please note: This range reflects the expected base salary for this role but may not represent the full compensation range for all experience and skill levels. During the recruitment process, we will discuss and consider how your unique qualifications align with the broader range for this position.

Gore Mutual is proud to offer a comprehensive total rewards package which includes extended health and dental benefits, disability insurance, retirement plan matching, paid time off, recognition and perk programs.

Position Summary

The Clinical Trial Manager (CTM) is responsible for the execution, and oversight of global clinical trials, ensuring high-quality delivery in alignment with ICH-GCP, regulatory requirements, and corporate objectives. This role provides day-to-day operational management of CROs and vendors and contributes to the development of processes that support the growth of the Clinical Operations function. This position requires on site presence in the Alkeus office in Cambridge, MA.

Responsibilities

• Manage daily clinical trial operations for a global clinical trial across all trial phases (startup through closeout), ensuring adherence to timelines, budget, and quality standards.
• Coordinate cross-functional team activities, document review.
• Oversee CRO and vendors, monitor performance metrics, and ensure timely and high-quality deliverables.
• Provide monitoring oversight, including participation in co-monitoring visits, reviewing monitoring reports, confirming follow-up on action items and escalating issues.
• Support start-up activities to help accelerate site activations
• Oversee site management and site engagement initiatives to maintain strong site relationships.
• Lead study-specific meetings, including internal team meetings, CRO/vendor meetings.
• Provide input on key study documents including protocols, ICFs, eCRFs, and operational plans, etc.
• Track study timelines, enrollment, protocol deviations, data trends, and sample management in partnership with CRO and internal stakeholders.
• Support risk identification and mitigation planning efforts.
• Maintain inspection readiness and ensure compliance with SOPs and regulatory standards.
• Prepare regular study updates, presentations, and risk assessments for senior leadership.
• Contribute to process improvement initiatives, development of SOPs, and operational best practices for the Clinical Operations department.

Qualifications

• Bachelor’s degree in a scientific or health-related field required; Advanced degree preferred.
• Minimum 5 years managing clinical trials and 8+ years of industry experience.
• Experience managing outsourced global clinical trials across Phase I–III strongly preferred.
• Experience managing phase III trials is a must.
• Strong knowledge of ICH-GCP and global regulatory requirements.
• Experience in biotech/pharma environment required.
• Ability to manage multiple tasks in a fast-paced environment.

• Skills and Key Success Factors:
  • Entrepreneurship spirit with a passion to build, learn and evolve with the team
  • Highly organized and detail oriented with a passion to deliver quality results
  • Excellent verbal and written communication skills, with experience translating complex concepts for various audiences
  • Demonstrated record of intellectual curiosity, innovation and creative problem solving with an entrepreneurial spirit
  • Ability to lead fast-paced projects with a keen sense of urgency to get the job done well
  • Evidence of "hands-on" experience and expertise
  • Proven and successful track record as a team-player and collaborator in small working environments
  • Highest levels of professionalism, confidence, personal values and ethical standards

Other Relevant Information:

• Travel:  As required

Compensation

• Base Salary Range: $140,000 - $160,000, with the actual contingent upon several factors such as the selected candidate’s education/work experience/training, and other factors (travel requirements, etc.)
• Discretionary Bonus: up to 15% of Base Salary, contingent upon meeting performance components
• Equity: initial grant of incentive stock options
• Benefits: Eligible to participate in group medical/dental/vision insurance plans; short- and long-term disability plans; life insurance; 401(K) plan; flexible time off policies and others. Eligibility and participation requirements vary by plan.

The Role:

Reporting to the Associate Director, Clinical Operations, the Sr. Manager, Clinical Operations will ensure excellence in clinical trial planning, execution, and data collection, in accordance with regulatory guidelines. You will be working on a clinical study with responsibilities including site selection, contract negotiation, budget management, study start-up, conduct and close-out.  This role will collaborate with cross-functional study team as well as demonstrate excellent management of and partnership with CROs and vendors. The ideal candidate has a track record of executing complex, on-time clinical trials at a biotech/pharmaceutical company and delivering high quality clinical trial results.  

Responsibilities:

• Contribute to one or multiple clinical studies and demonstrate thorough knowledge of clinical operations project management. Collaborate with cross-functional clinical study team to support clinical study delivery.
• Evaluates, and ensures appropriate oversight of CROs and other external vendors.
• Ensure clinical trials are executed according to scope of work, budget, timelines, KPIs, and corporate goals.
• Establish and maintain effective communication and collaboration with functional area peers to meet clinical study objectives and support goals.
• Identify risks and propose solutions to facilitate clinical studies.
• Responsible for review and oversight of the study-level budget(s) and demonstrates accountability for the management of the budgets through managing the review and approval of contracts and/or work order changes; contribute to budget forecasting and accruals in collaboration with finance.
• Oversee and manage the creation, maintenance, QC and close out of TMF activities.
• Ensure appropriate oversight of enrollment, site activation and data collection milestones.
• Contribute to and support team to ensure the completeness of study documents including, study protocol, investigator brochure, informed consent forms, clinical study reports and case report forms.
• Collaborate with Data Management to ensure timely and efficient database lock. Participate in data review and reconciliation efforts.
• Lead or co-lead department initiatives to support an expanding organization.
• Travel may be required (10% – 15%).

Competencies Include:

• Detail and process orientated, with excellent project management skills, including risk assessment and contingency planning.
• Excellent problem solving, communication and organization skills.
• Flexibility with changing priorities, ability to think critically, strong attention to detail, and ability to work well under pressure.
• Ability to work in a collaborative environment and build effective working relationships across the organization.
• Demonstrated leadership and ability to strategically plan, organize and manage multiple projects simultaneously.

 Qualifications:

• At least 5 - 7 years of Clinical Operations experience.
• Bachelor’s degree or higher in a scientific or healthcare discipline preferred and relevant experience within the biotech, pharmaceutical, or CRO industry.
• Extensive knowledge of current ICH-GCP guidelines.
• Relevant experience managing early through late Phase clinical trials.
• Demonstrated cross-functional leadership fostering team spirit and team motivation.
• Capability to challenge status-quo using risk management approach.
• Able to thrive in a remote/virtual environment.

Additional Information:

Nuvalent is committed to fair and equitable compensation practices, aiming to provide employees with competitive total rewards packages.

The targeted salary range below reflects what Nuvalent reasonably and in good faith expects to offer for this position at the time of posting, but the final salary determination may be within or outside this range based on various factors, including, but not limited to, experience, skills, education, and market factors.  The range will be reviewed regularly and is subject to change.

Nuvalent also offers a comprehensive benefit package to support our employees at each stage of their career, financial, health, and well-being journey, including medical, dental, and vision insurance, 401(k) retirement savings plan, generous paid time off (including a summer and winter company shutdown), and much more.

About the role

Sana Biotechnology is growing, and we are hiring new team members who believe in the potential of engineered cells as medicines, who want to challenge status quo, and who lead with the desire to work on novel ideas.  As an Associate Director, External Manufacturing you will report to the Executive Director, External Manufacturing to oversee day-to-day operational performance of key Sana contract development and manufacturing organizations (CDMOs). This will include coordinating and driving activities for pre-clinical and clinical phase drug substance (DS) and/or drug product (DP) manufacturing for Sana’s cell and gene therapy programs at 3rd party CDMOs. You will be an essential business partner within Technical Operations and will support Sana's manufacturing strategy to bring Sana's pipeline to patients across the world.

What you’ll do

• Acts as primary liaison and relationship manager between Sana Technical Operations and the CDMO to ensure timely delivery of high quality pre-clinical and clinical CGT product(s)
• Responsible for adherence to project schedule(s)
• Implement and execute governance structure with CDMO(s)
• Develops and oversees budget(s) for project(s) under their purview, including contributing to internal Sana budgeting activities and ensuring CDMO performance to financial plan in collaboration with Sana accounting.
• Partner with our technical departments to help ensure success of tech transfer activities from Sana to the CDMO partner.
• Monitors technical transfer and production campaign activities and reports on CDMOs performance against plans
• Identifies, notifies, and/or escalates risks and issues that may affect project timelines, resource requirements, finances, or business relationships
• Executes strategies that drive effective operational performance and service levels at contract organizations
• Negotiates and facilitates approval of contracts including proposals, master supply agreements, work orders, and changes of scope.
• Effectively communicates project, performance, and resource issues to management and within project teams
• Ensure CDMOs deliver to support Sana’s business needs including ensuring flexibility to accommodate changing program timelines and compliance with GMP practices as well as Sana's quality expectations

What we’re looking for

• Bachelors degree with 5+ years plus of outsourced clinical and/or commercial manufacturing experience in the biotech/pharmaceutical industry
• Knowledge and understanding of the regulatory guidelines and working experience in the GLP and GMP environment, including knowledge of cGMP quality systems
• Experience operating in early-stage clinical to commercial environments
• Ability to communicate across all levels of an organization and efficiently coordinate activities with both internal and external customers.
• Proven ability to problem solve, build strong relationships, and to organize effectively
• Business acumen with an ability to anticipate operational issues and proactively recommend mitigations/solutions
• Results-oriented and demonstrated focus on achieving business results. Experience with project team meetings, cross-functional communication, supporting decision making, influencing outcomes, and ensuring alignment among internal and external stakeholders
• Successful track record of developing cooperative, productive relationships across all functions with people at all levels within and external to the organization
• High degree of self-motivation
• Ability to quickly adapt to changing business conditions

What will separate you from the crowd

• Prior experience working with cell and gene therapy CDMOs

What you should know

• The base pay range for this position at commencement of employment is expected to be between $170,000 and $210,000/year; however, base pay offered may vary depending on multiple individualized factors, including market location, job-related knowledge, skills, and experience 
• Up to 25% travel (domestic and/or international)

What You Will Contribute To Altos

As a Senior Project Manager at Altos, you will act as an operational anchor with a big-picture mindset for the Institute of Computation (IoC). Leveraging your own background in science, you will bridge the gap between complex biological questions and rigorous operational execution using project management. You will not just track tasks; you will actively shape how cross-functional teams of biologists, data scientists, and machine learning scientists and engineers collaborate to achieve ambitious goals. This role is designed for an operational expert who excels at translating abstract scientific goals into actionable project plans, connecting the dots between daily tasks and broader program objectives, and ensuring alignment across computational, scientific, and business units.

Responsibilities:

• Plan & Execute: Translate high-level scientific intent into actionable project plans for 4-6 multidisciplinary projects. Maintain and track visibility on goals, milestones, dependencies, and timelines to ensure delivery within scope and budget.
• Operational Execution & Big Picture Alignment: Collaborate closely with scientific leads to translate their vision into reality. You will ensure the team understands how their daily tasks contribute to the broader mission, proactively identify risks, and drive the accountability needed to ensure research milestones are met on time and within scope.
• Operational Coordination: Coordinate team operations, including meeting cadence, agendas, and workflows. Ensure meetings are effective, focused, and result in clear action items.
• Documentation & Knowledge Management: Own the "single source of truth" for projects. Document meeting notes, key decisions, and lessons learned, ensuring they are accessible to all stakeholders.
• Cross-Functional Communication: Serve as the bridge between diverse disciplines to ensure seamless handoffs between scientific, computational, and business units.
• Process Improvement: Design and implement pragmatic workflows that improve operational efficiency without creating unnecessary bureaucracy.

Who You Are

Minimum Qualifications:

• Education: BS or MS in life sciences, computational biology, business, or a related field.
• Experience: 
• 5+ years of project management experience within biotechnology, computational biology, AI/ML, or pharmaceuticals. 
• Experience managing large-scale data generation (omics, imaging) and machine learning model development is highly preferred. 
• You started your career 'at the bench' (wet lab or computational) and made a deliberate pivot into professional Project Management.
• PMP, PRINCE2, or Agile certifications are a plus, but real-world experience managing complex R&D portfolios is prioritized.
• Deep Project Management Toolbox: You are an expert in a range of project management methodologies (Agile, Waterfall, Kanban, Hybrid) and know exactly when to deploy which tool. You don't force "process for process's sake"; you pragmatically select the right framework to fit the ambiguity of early-stage discovery.
• Strategic & Tactical: You function at dual altitudes - comfortable understanding the broader roadmap one hour, and deep-diving into Jira tickets, meeting minutes, or resource allocation the next.
• Communicator & Influencer: You can translate complex technical goals for diverse audiences and have the confidence to influence stakeholders without formal authority.
• Operational Mindset: You are an analytical problem-solver who is results-driven, detail-oriented, and able to work autonomously with minimal supervision.
• Tool Proficiency: High proficiency in project management platforms (e.g., Jira, Smartsheet) and Google Suite.

The hourly range for remote in the UK only:

• Hourly rate range: £29.00 - £36.00

Exact compensation may vary based on skills, experience, and location.

Before submitting your application:

- Please click here to read the Altos Labs EU and UK Applicant Privacy Notice (bit.ly/eu_uk_privacy_notice)
- This Privacy Notice is not a contract, express or implied and it does not set terms or conditions of employment.

#LI-NN1

About Blank Street

At Blank Street, we’re on a mission to become the defining food and beverage brand of our generation. From the very beginning, we’ve set out to add a spark to ordinary experiences through elevated products, attention-to-detail, and a commitment to making every moment memorable. We’re motivated by the millions of customers we serve across cities, and know that our potential is unlimited. It all starts with our people and their commitment to make magic happen each and every day.

Start Something Extraordinary…

As a Shift Leader at Blank Street, you are a born player-coach who thrives when working alongside a team to deliver quality products. You are a proven people-person who takes pride in giving amazing service experiences and influencing your team to do the same. You thrive for opportunities to serve your community and make a big local impact. You are customer centric and believe in quality products through flawless execution, making every effort to give your customers exactly what they need, every day, in their way. You excel in fast paced environments and enjoy an inclusive, collaborative workplace, where your voice genuinely counts, and you can really make a difference.

You will spearhead individual, team and location initiatives to drive sales and business performance. Along with supporting your General Manager to lead these important company initiatives, you will regularly meet with the Senior Leadership team to voice feedback, improvements and overall be hands on in the success of your store, your customers and your teams’ best interests. You would be one of the first staff members to work in this location, which means you get the exciting opportunity to set the tone and create lasting connections in the neighbourhood.

Who We’re Looking For

• Love for cafe culture and people
• Friendly, open and approachable person who is able to work well with others
• Strong knowledge of coffee and equipment is a must
• Strong decision-making and multi-tasking skills
• Strong interpersonal communication skills
• Passionate about delivering excellent customer connections to create a regular customer base
• Able to work at a fast pace in high-volume environments
• Be an exemplary ambassador of our brand to new neighbourhoods

What You’ll Own

• Craft beautiful coffee products and serve all Blank Street customers with energy, warmth, and empathy
• Support your GM and our Training Team to help train new employees to succeed at Blank Street, including ensuring that new team members are following all recipes and training for menu items and processes and that they are in the correct uniform, are upbeat and vibes are positive
• Open and close the location safely and responsibly (Key holder) and ensure that cleaning duties for the store are followed at the beginning, during and end of the shift
• Positive and solution-focused handling of any minor customer issue
• At a store level, leads all initiatives with the operations and marketing teams to increase foot traffic, new customers, daily sales, and operational profitability and develop a loyal neighbourhood customer base for your store

Requirements

• Experience in the customer service or hospitality industry
• Availability that meets the needs of our cafes
• Full Time: 35 hours per week, 5 days of availability required and must be available to work 2 peak days (Peak days: Friday, Saturday, Sunday)
• Availability to work between 6:30 am and 9:00 pm
• Weekend and holiday availability preferred
• You must be authorised to work in the UK

The Opportunity

Proton is building the industry cloud for distribution—an $8 trillion market that technology forgot.

Our first product is an AI-powered CRM built specifically for distributors—it helps their sales teams know which customers to call, what to sell them, and when. We're at ~$10M ARR with 120%+ NDR. Our second product, PIM (Product Information Management), helps distributors manage their product catalogs—think millions of SKUs with specs, images, and pricing that need to stay accurate across systems. PIM is growing fast. Another product launches in March, with more on the roadmap.

We're looking for a Senior Financial Analyst to be our finance lead. You'll own the function—building our operating model, running FP&A, managing reporting and compliance, and working directly with the CEO on financial decisions. You'll have one direct report (our bookkeeper) and full ownership of how finance runs at Proton.

If you succeed, you'll have built the finance infrastructure that supports Proton's growth from $10M to $50M+ ARR. 

We are looking to hire someone in the greater Boston area who is open to a hybrid schedule (3 days in office, Havard square). The target salary range for this role is $140,000- $170,000. Final offers will be based on your skills and previous experience.

What You'll Do

Own FP&A (40%)

• Build and maintain our operating model and budget
• Prepare monthly budget vs. actuals reporting
• Track and report on SaaS metrics (ARR, NDR, CAC, LTV, magic number, etc.)
• Prepare board materials and investor reporting
• Build bespoke financial analysis for business decisions

Run Financial Operations (40%)

• Oversee accounting: revenue recognition, month close, AP/AR
• Own billing, collections, and cash management
• Ensure compliance: corporate tax, sales tax, R&D tax credit, 409a valuations
• Calculate and manage variable compensation and partner commissions
• Lead Fiona (bookkeeper) and manage external accounting relationships

Partner with the CEO (20%)

• Be a thought partner on financial decisions
• Support fundraising preparation when needed
• Identify opportunities for financial process improvement

Who You Are

Non-Negotiables:

• SaaS metrics fluency. You understand ARR, NDR, CAC, LTV, burn multiple, and magic number cold.
• Financial modeling skills. You've built operating models from scratch and can maintain them as the business evolves.
• Startup experience. You've worked at a Series A or B stage company and understand the pace and ambiguity.
• Based in Boston. In office 3x/week in Kendall Square.
• Exceptional attention to detail. Your models are airtight. Your reports are accurate. You catch things others miss.

What Sets You Apart:

• You're reliable. When you say something will be done, it gets done—on time and correctly.
• You're curious. You dig into the numbers to understand what's really happening in the business.
• You communicate clearly. You can explain financial concepts to non-finance people and help them make better decisions.

About Proton

Distribution is an $8 trillion industry that technology forgot. 75,000+ distributors globally. Half of their sales reps still don't use a CRM. The ones that do are stuck with generic tools built for tech companies—not businesses managing millions of SKUs and thousands of customer relationships.

We're building the industry cloud for distribution—and every product is AI-native from the ground up. We're not bolting AI onto legacy software. We're rebuilding the entire stack with AI at the core.