The Opportunity:

Relay Therapeutics is seeking a highly motivated Scientist to join our Drug Discovery team in a unique hybrid role that integrates synthetic chemistry with cheminformatics. This position is ideal for a scientist who enjoys working at the interface of experimental and computational disciplines and is excited to help shape how data-driven chemistry is done in a modern biotech environment.

Your Role:

• Maintain and support tools used in compound registration, lab operations and data ingestion from assays, as well as broader data and software access workflows
• Design and execute synthetic chemistry workflows, with a focus on high-throughput or parallel synthesis to support medicinal chemistry programs
• Contribute to the design, enumeration, and prioritization of compound libraries using cheminformatics tools
• Collaborate closely with computational chemists, data scientists, and medicinal chemists to guide compound design using data-driven insights
• Analyze and interpret experimental data to inform structure–activity relationships (SAR) and compound optimization
• Help develop and refine internal workflows that integrate synthetic chemistry with computational approaches
• Maintain clear documentation and communicate results effectively across multidisciplinary teams

Your Background:

• Ph.D. or M.S. in Organic Chemistry or a related field, with 2–5 years of relevant industry experience preferred
• Demonstrated experience in synthetic organic chemistry
• Familiarity with cheminformatics tools and concepts (e.g., molecular representations, library design, property prediction)
• Experience with scripting or data analysis tools (e.g., Python, RDKit)
• Strong problem-solving skills and the ability to work both independently and collaboratively
• Excellent communication skills and a desire to work in a highly cross-functional environment

What We’re Looking For

• A scientist who enjoys bridging “hands-on” chemistry with computational thinking
• Someone comfortable working in a fast-paced, evolving biotech setting
• A candidate who is curious, adaptable, and interested in shaping new ways of integrating chemistry and data science

Estimated Salary Range: [$88,000-$126,000].

The range provided above is based on what we believe to be a reasonable estimate for this job at the time of posting. Actual base salary will depend on a number of factors, including but not limited to, a candidate’s education, experience, skills and location.

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The Opportunity:

As part of the Pharmaceutical Development team, this position will play a key role in regulatory strategy development and execution of assigned Chemistry, Manufacturing and Control (CMC) programs.

Your Role: 

• You will serve as CMC-regulatory lead for assigned projects.
• Develop and execute CMC global submission plans and timelines in accordance with project goals
• You will lead the preparation/plans, review, and on-time submission of CMC sections for IND/IMPD/CTA, NDA/MAA and other global regulatory filings including IB, DSUR, annual updates, briefing books etc. in conjunction with regulatory affairs and CMC/Pharmaceutical Development leads/SMEs.
• You will be responsible for coordination of responses to CMC questions/RFIs from regulatory authorities in conjunction with CMC and regulatory affairs leads/SMEs.
• You will lead CMC-regulatory activities listed above with cross-functional teams and act as the regulatory CMC liaison between CMC/PD, regulatory affairs and/or program management, as applicable.
• You will lead and manage CMC-regulatory assessment and guidance on product compliance topics, including change controls, deviations, and GMP investigations, in conjunction and consultation with CMC leadership.
• You will keep abreast of regulatory guidance and technical/scientific developments relevant to projects.

Competencies:

• Strong background in Regulatory Affairs-CMC with a focus on small molecule clinical (IND/IMPD) and/or commercial (NDA/MAA) submissions.
• Proven ability to lead and manage regulatory CMC projects with minimal supervision
• In-depth knowledge of global CMC regulatory requirements and guidelines (e.g. FDA, EMA, ICH).
• Positive attitude, energetic and proactive.
• Strong technical writing and document review skills.
• Excellent organizational skills, ability to multi-task and prioritize assignments, operational creativity, strong problem-solving skills, self-motivated and able to work under pressure.
• Strategic thinking capabilities with forward looking perspective and ability to find solutions, in alignment with management and program goals, strong communication, planning, and collaboration skills
• Attention to detail, follow-up/through skills; ability to work individually and within multi-disciplinary internal and external teams at third parties.
• Ability to effectively manage multiple projects with competing priorities.

Your Qualifications:

• Bachelor or advanced degree in Pharmaceutical Sciences, Chemistry or related fields.
• Minimum of 8+ years of relevant experience in regulatory-CMC and/or within CMC function (e.g. analytical, formulation and process development, QA, QC) in the biotech/pharmaceutical industry with a focus preferably on CMC for small molecules and oral solid products.
• Experience with authoring/review/providing CMC content for CMC/quality submissions including IND and IMPD development/maintenance.
• Knowledge of eCTD Module 3 and QOS requirements for INDs/IMPDs and NDAs/MAAs.
• Experience managing submissions in RIM Veeva or equivalent; document formatting/Quality Control compliant with eCTD templates / requirements.
• Authoring experience of CTD Module 2 & Module 3 sections.

Estimated Salary Range: [$145,000 - $207,000].

The range provided above is based on what we believe to be a reasonable estimate for this job at the time of posting. Actual base salary will depend on a number of factors, including but not limited to, a candidate’s education, experience, skills and location.

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The Opportunity

We are seeking a highly motivated Manager of Financial Planning & Analysis (FP&A) to join our established finance team at a well-positioned, clinical-stage precision medicine company in Kendall Square. This is an excellent opportunity for a finance professional who thrives in a dynamic, collaborative environment and is eager to make a meaningful impact across the organization.

This role will report to the Senior Director of FP&A and will play a key role in supporting our development organization through accrual reporting, planning, and analytical activities as well as supporting our recurring management reporting deliverables

Your Role

• Track and analyze clinical site budgets, providing visibility into spend and key trends
• Support the analytics for our clinical trials including the clinical accruals process, and business partnering with key cross-functional stakeholders
• Preparation and delivery of key monthly reporting including monthly financial reporting and headcount analytics
• Trusted FP&A business partner to our G&A departments (Finance, IT, HR, Legal, and Operations)
• Perform ad hoc financial analysis to support decision-making across the development organization
• Assist with budgeting, forecasting, and long-range planning processes
• Prepare presentations and materials for cross-functional partners, translating data into clear and compelling financial insights
• Continuously improve financial processes, models, and reporting tools

Your Background

• Bachelor’s degree in Accounting, Finance, or related field (required)
• 5+ years of progressive experience in finance or accounting (biotech or life sciences experience preferred)
• Strong proficiency in Microsoft Excel and PowerPoint (required)
• Experience with Adaptive Planning or similar financial planning tools (preferred)
• Solid understanding of financial statements, budgeting, and forecasting processes
• Strong analytical, problem-solving, and communication skills
• Ability to manage multiple priorities and work effectively in a fast-paced environment
• Detail-oriented with a high degree of accuracy and accountability

Why Join Us?

• Join a collaborative, well-established finance team
• Contribute to a mission-driven company making a meaningful impact for patients
• Gain exposure to cross-functional teams and senior leadership
• Opportunity for growth and professional development

If you're looking to take the next step in your finance career and want to contribute to a high-impact organization, we’d love to hear from you.

Estimated Salary Range: [$98,000 - $140,000].

The range provided above is based on what we believe to be a reasonable estimate for this job at the time of posting. Actual base salary will depend on a number of factors, including but not limited to, a candidate’s education, experience, skills and location.

#BP1

The Opportunity:

As a Senior / Medical Director at Relay Tx, you will help advance our clinical pipeline from IND to proof of concept to registration.  Specifically, you will collaborate with senior medical staff to drive clinical strategy, clinical trial design, and execution.  Working cross-functionally with clinical project management, regulatory affairs, clinical operations, biostatistics, data management and medical writing, you will play a key role as Relay Tx continues to introduce product candidates into the clinic.  You will provide clinical leadership to R&D teams and will work closely with Development leadership.   

We are open to remote employees

About You:  

• Collaborate with senior medical staff, drug discovery teams, translational oncology, clinical operations, clinical investigators and disease-specific experts to design and execute early clinical development plans that definitively test key translational hypotheses for Relay Tx medicines and establish clinical proof-of-concept as soon as possible after entering human testing. 

• Write clinical sections of key documents, including Investigator’s Brochures, IND summary documents, CTAs for initiation of ex-US studies and work with senior medical staff for responses to questions from regulatory authorities, IRBs, and ethics committees. 

• Provide expert medical review, assessment, and interpretation of clinical data and prepare results for presentation to internal clinical development leadership and external stakeholder including regulatory authorities.  

• Manage drug safety and pharmacovigilance activities for ongoing trial(s). 

• Attend and support clinical site initiation visits. 

• Rapidly integrate new insights derived from on-going Relay Tx or external clinical trials, translational science or basic science into Relay Tx development plans and clinical trial activities. 

• Collaborate with research leadership and drug discovery teams to shape the Relay Tx drug discovery portfolio. 

• Proactively manage communication and build strong collaborative relationships with key stakeholders.

• Ensure Relay Tx maintains the highest standards of compliance and ethical behavior in the design, conduct, interpretation and communication of clinical trials, clinical trial data, and clinical trial results. 

Your Background:  

• Experience working with solid tumors.
• A dynamic team player and effective communicator that thrives in a fast-paced environment. 
• MD, MD/PhD or other advanced degree with 5+ years of clinical development experience in academic and/or industry settings with work in oncology.  Motivated candidates with lesser experience and a passion to learn precision oncology clinical development and contribute to cross functional development teams will also be considered.
• Exposure to design and execution of clinical trials; protocol development and design, development of case report forms, and statistical analysis plans. 
• Exposure to working closely with investigative sites, including principal investigators, sub-investigators, study coordinators, and other site personnel involved in clinical trials. 
• Excellent written and oral communication skills. 
• The successful applicant will thrive in the Relay Tx corporate culture where the core values are relentless, fearless, craftsmanship, candor, and humanity. You will be a key contributor to Relay clinical development and enabled to make a significant positive impact for patients. 

Estimated Salary Range: [$213,000 - $350,000].

The range provided above is based on what we believe to be a reasonable estimate for this job at the time of posting. Actual base salary will depend on a number of factors, including but not limited to, a candidate’s education, experience, skills and location.

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