About the California Academy of Sciences

The California Academy of Sciences is a globally renowned scientific and cultural institution located in the heart of San Francisco’s Golden Gate Park. Home to a world-class planetarium, aquarium, research center, and natural history museum—all under one living roof—our mission is to regenerate the natural world through science, learning, and collaboration.

Our extensive collections span plants, animals, fossils, and cultural artifacts from across the globe and throughout history. We are a diverse team of leading biodiversity scientists, educators, storytellers, designers, and communicators who work collaboratively to advance knowledge and inspire action through science and storytelling.

When you join the California Academy of Sciences, you become part of a mission-driven community that values curiosity, collaboration, and innovation. Whether you're working behind the scenes in research or engaging the public on the museum floor, your work will help connect people to the natural world and empower them to protect it.

About the Opportunity

Reporting to a department lead, the Part-time Biologist I is responsible for providing animal care for the Steinhart Aquarium’s living collection in various exhibit areas as assigned. Cleans habitats and holding areas, monitors animal and plant health, makes frequent daily rounds, reports suspected animal or water quality problems to a department lead, maintains accurate records. Work schedule will include weekends, evenings and holidays. 

Organizational Culture
Join a team dedicated to the Academy’s mission, vision and values! Currently, the Academy has a new strategic plan including three initiatives – Hope for Reefs, Thriving California, and Islands 2030 – that leverage biodiversity science, environmental learning, and collaborative engagement to regenerate fragile ecosystems around the world. Learn more at https://www.calacademy.org/about-us/major-initiatives.

We hope you are inspired by what we do and are excited to contribute to our mission. The mission of the California Academy of Sciences is to regenerate the natural world through science, learning, and collaboration. The Academy is looking for candidates who do great work, and we know they may come from a number of different backgrounds and experiences. We encourage you to apply even if you do not believe you meet every qualification for the position.

This position is based in San Francisco, California. The specific onsite/hybrid schedule for this position is listed below. This position is part of a bargaining unit represented by Cal Academy Workers United, and will be subject to the terms and conditions of that contract.

About the Steinhart Aquarium

Steinhart Aquarium is one of the most biologically diverse and interactive aquariums on Earth. Home to more than 60,000 live plants and animals, representing more than 1,000 unique species, it offers guests an unprecedented view of underwater and terrestrial habitats. Since 1923, Steinhart Aquarium has developed a colorful history of firsts. From becoming the first public aquarium to display flashlight fish and coconut octopuses to advancing exploration of the ocean’s mysterious “twilight zone,” innovation and scientific excellence are in our DNA. Today, Steinhart continues to shape the role that modern aquariums play in educating and inspiring the public about the biodiversity and sustainability of our oceans and rainforests.

Key Responsibilities

• Provides daily animal and plant care and habitat maintenance including animal feedings, habitat and back of house cleaning, health monitoring and environmental sampling for one or more of the following: fresh and saltwater aquariums, terrestrial invertebrate, reptile, amphibian, bird, plant and mammal habitats and holding areas.
• Actively participates in the animal welfare and behavioral husbandry programs.
• Assists in animal treatments and procedures as required.
• Assists in the design and preparation of new display environments and habitats.
• Actively seeks further training with all taxa represented in the living collection.
• Maintains accurate records using the department’s standardized software programs.
• Effectively communicates to the Aquarium management and staff.
• Establishes and maintains positive, cooperative and effective working relations with fellow employees.
• Participates in Academy committees and work groups as needed.
• Presents programs to the general public, media and in professional meetings.
• Interacts with professional colleagues, guests, the media and the general public in a professional manner.
• Follows all Academy safety regulations.
• Performs other job-related duties as assigned.

Qualifications: A successful candidate will have the following:

Experience and Education:

• Previous work (paid or unpaid) experience in an aquarium, zoo or similar facility caring for animals and/or plants required.
• Bachelor’s degree in Biology, Zoology, Aquatic Biology or a related field, preferred.

Required Skills and Abilities:    

• Basic knowledge of essential animal care and welfare requirements for the living collection.
• Basic knowledge of USDA and AZA standards for animal care and welfare.
• Basic knowledge of public aquarium/zoo operations, maintenance, record keeping and life support systems.
• Excellent observation skills.
• Effective verbal and written communication skills.
• Effective organizational and problem solving skills.
• Ability to multitask, adapt, and prioritize.
• Ability to read and interpret documents such as departmental protocols, safety rules, operating and maintenance instructions, and procedure manuals.
• Ability to present programs and effectively convey information to guests, the general public, the media, colleagues, and in professional meetings.
• Ability to work as a member of a team and engage in a culture that promotes trust, respect and accountability.
• Ability to utilize web-based communication and collaboration applications.
• Willingness to seek further training in animal and plant husbandry.
• Ability to complete CPR/AED/First Aid certification.
• Ability to work weekends and holidays on a routine basis.
• Experience with scientific research projects, preferred.

Physical Environment:

• Ability to transport 50 lbs.
• Ability to perform repetitive motions 75% of the time.
• Requires the ability to stand, sit, walk, and reach with hands and arms, and talk or hear.
• Must be able to work a computer. 
• Must be able to climb stairs and ladders.
• Must be able to swim.
• Must be able to use extension poles, long-handled nets and shepherd’s hooks.
• Must be able to work with, or adjacent to, venomous and dangerous animals.

To perform this job successfully, an individual must be able to perform each essential job duty satisfactorily. Reasonable accommodations may be made to enable qualified individuals with disabilities to perform essential job functions.

Compensation and Benefits:
The hourly range for this position is $27.64. Actual compensation will be commensurate with the final candidate's qualifications and experience, including skills, knowledge, relevant education, certifications and aligned with the internal peer group. We believe in fair and equitable compensation practices and are committed to providing competitive salaries within the industry and market standards. The Academy offers a total compensation package that emphasizes both base salary and comprehensive benefits based on the hours per week worked. Further details regarding compensation and benefits will be discussed during the interview process.

Schedule: Part-time temporary, 24hours per week, in-person

How to Apply:

Interested candidates should submit a resume and application through our Careers Page portal.

The California Academy of Sciences will give full consideration for employment to all qualified applicants with criminal histories in a manner consistent with the requirements of the San Francisco Fair Chance Ordinance (SF Police Code, Article 49).

An affiliate of Colossal is seeking a Developmental Biologist that will work to design and conduct experiments that will inform genetic engineering for avian de-extinction projects. Leveraging their expertise in genetics and developmental biology, they will work closely with bioinformaticians to identify genetic variants of interest and test the effect of those variants in an embryonic avian model.

**This position is based out of Dallas, TX. Relocation assistance is available**

Duties and Responsibilities:

• Maintain expertise and familiarity with genetics and development literature 
• Work closely with the bioinformatics team to identify genetic variants of interest
• Perform in ovo electroporations and manipulations on avian embryos
• Process, image, and analyze avian embryos of various stages using techniques such as fluorescent microscopy, whole mount skeletal staining and morphometrics
• Design, develop, and implement novel experiments, techniques, procedures, protocols, and systems in line with research program objectives for non-model birds
• Contribute to, and be responsible for, documentation, reports, presentations and publications associated with work 

Skills and Abilities:

• Experience with avian embryo manipulation, such as in ovo electroporation or embryonic tissue transplantation, OR relevant experience in other embryonic systems
• Strong working knowledge of gene regulatory networks in embryonic development
• Strong working knowledge of research methodology and study design; hypothesis testing; qualitative and quantitative data interpretation and application
• Exceptional verbal and written communication skills
• Demonstrated ability to take the initiative to move projects forward, make independent judgments, maintain accurate lab data, clearly understand and respond to experimental results, while communicating effectively 
• Ability to work independently and collaboratively, as required, in a fast-paced, matrixed, team environment consisting of internal and external team members
• Analytical and creative thinker with excellent problem-solving skills and the ability to prioritize own work and adapt to changing team priorities
• Excellent planning, organization and time management skills 
• Very high level of comfort with productivity and communication software platforms (MS Office, GSuite, Slack, digital notebooks, project management systems, etc.)

Qualifications:

• DVM/PHD in developmental biology, biological sciences, veterinary medicine, bioengineering, molecular biology, genetics, or any science related field is required
• 2+ years of experience in developmental biology strongly preferred
• 2+ years of experience working with avian eggs and embryos strongly preferred

The Opportunity:

We are looking for motivated structural biologist to join tour team to support multiple oncology therapeutic programs. The ideal candidate will have previous, hands-on experience in sample preparation, data acquisition and data analysis from both X-ray crystallography and cryo-EM. They will apply their expertise to form compound driven complexes, identify, and optimize crystallization/CryoEM conditions with the aim of determining high resolution structural information to drive small molecule design and mechanistic understanding. We’re seeking a team player with enthusiasm to work in an interdisciplinary setting to drive toward new, cutting edge oncology therapeutics. 

Responsibilities

• Plan and execute experiments with the aim of determining small molecule driven multi-protein complex structures by CryoEM and X-ray crystallography.

• Perform cryo-EM grid screening, optimization, data collection and refinement to enable high-quality structure determination.

• Interact with interdisciplinary teams (including chemists, computational chemists, biologists, project teams, and management) and clearly articulate structural data in a broader drug discovery context.

• Maintain excellent records and communication among internal and external colleagues.

• Be driven by a desire to be innovative in a high energy, fast paced environment and work collaboratively with a variety of collegues across the organization.

Required Skills, Experience and Education:

• PhD in structural biology or protein biochemistry or a related scientific discipline with 2-5 years of post-doctoral experience.

• Hands-on experience and expertise in cryo-EM sample optimization and grid preparation, data collection, map generation, and structure determination.

• Strong track record of solving challenging CryoEM problems such as preferred orientation, small proteins/complexes, modeling into low resolution maps, or iterative rounds of protein optimization.

• Hands on experise with modern software packages for data collection, refinement and visualization of structural biology data, and the ability to seamless switch between them based on need (e.g. CryoSPARC, RELION, Phenix, REFMAC, Coot, ChimeraX, Pymol).

• Excellent written, verbal communication, interpersonal and organization skills.

• Conscientious team-player interested in a fast-paced biotech environment.

Preferred Skills:

• Hands-on experience and expertise in protein crystallization, crystal optimization and harvesting for data collection.

• Experience with biophysical characterization methods, including mass spectrometry, SEC-MALS, DLS, SPR, NMR and thermal shift assays.

• Experience with protein-protein complexes including antibodies/Fabs, molecular glues, PROTACs, etc.

• Experience working in a multidisciplinary team environment.

• Experience in gene construct design, expression and purification of recombinant proteins. 

  #LI-Hybrid  #LI-LN1

The Team You’ll Join 

As part of Recursion's Value Tech Tooling Team, you will be at the forefront of reimagining drug discovery from first principles using our massive data capabilities. You'll work in a cross-functional team of world-class computational biologists and engineers who turn complex analyses and data workflows into stable tools and pipelines that multiply their impact and industrialise the discovery process across a wide array of therapeutic areas. You'll partner with biologists, medicinal chemists, engineers, data scientists, ML scientists, and to design experiments, develop new methods, build scalable data workflows, analyse results, and identify common themes across programs. As our toolbox grows and evolves, it will contribute to a revolution in drug discovery to bring life-changing therapeutics to patients at greater speed and with higher quality, safety and efficacy than ever before.

In this role, you will:

• Synthesize, integrate, and analyse diverse internal and external datasets from computational biology, target discovery, functional genomics, biomarker discovery, and real-world and clinically derived data sources, and identify commonalities to turn into reusable tools and pipelines.
• Build, maintain, and improve robust data pipelines and analytical workflows for complex biological datasets, including omics data, internally generated biological assay data, and external data sources such as Tempus and other real-world datasets.
• Develop and apply agentic workflows to integrate and orchestrate analyses across multiple internal and external data sources, accelerating insight generation and supporting scalable decision-making across drug discovery programs.
• Partner with engineers to mature pilot tooling and workflows into stable products and infrastructure that multiply the effectiveness of scientific collaborators pursuing drug programs.
• Present and discuss data, pipelines, and tools with decision makers and stakeholders in a clear and compelling way that drives toward getting medicines to patients.
• Collaborate cross-functionally with Recursion’s platform data science, data engineering, and ML teams to further advance Recursion’s ability to interpret and translate large-scale phenomics and multimodal data into therapeutic programs.

The Experience You’ll Need

• PhD in a relevant field (e.g., computational biology, bioinformatics, statistics, quantitative pharmacology, cancer/cell biology, computer science, or a related discipline), or equivalent experience, with a track record of applying these skills to fundamental problems in drug discovery.
• Experience applying computational methods (including statistical, probabilistic, and/or machine learning techniques) to analyse complex biological and/or human clinical data.
• Experience building, maintaining, and improving reproducible data pipelines and analytical workflows for large, heterogeneous biological datasets (Python strongly preferred).
• Experience working with high-dimensional biological datasets, including omics data (e.g., single-cell and other genomics-based modalities) and/or other complex assay modalities.
• Experience turning exploratory analyses into reusable tools, workflows, and documentation that can be adopted by other scientists/teams.
• General understanding of drug discovery and translational biology.

Nice To Have

• Experience working on highly collaborative cross-functional teams; ability to clearly explain computational analyses, data workflows, and methodologies to cross-functional and non-technical teams.
• Hands-on experience working with real-world clinical datasets (EHR/claims/registries) and/or generating real-world evidence (cohorting, endpoint definition, observational study considerations).
• Experience with real-world clinical datasets (e.g., EHR-derived oncology datasets) or demonstrated ability to rapidly learn new healthcare data modalities; experience with Tempus or similar datasets is a plus.
• Experience integrating multimodal datasets (e.g., genomics + phenomics, genomics + imaging) in service of translational decisions.
• Experience developing or applying agentic workflows to orchestrate analyses across multiple internal and external data sources, accelerating insight generation and decision-making

Working Location & Compensation:

This is an office-based, hybrid position at our office located in London, England. Employees are expected to work in the office at least 50% of the time.

At Recursion, we believe that every employee should be compensated fairly. Based on the skill and level of experience required for this role, the estimated current annual base range for this role is £86,300 - £115,500. You will also be eligible for an annual bonus and equity compensation, as well as a comprehensive benefits package. 

#LI-EP1

ESA is seeking a mid-level biologist with 2-7 years of experience in relevant scientific or environmental consulting environment.  This is an exempt, full-time, salaried role with hybrid flexible expectations. Qualified candidates must be located in the San Francisco Bay Area, vicinity of Sacramento, Sacramento-San Joaquin River Delta, Central Valley, or within 3 hours commute.  All qualified candidates must be willing & able to travel as needed. Preference given to candidates located in the bay area and central valley of CA. This role involves travel for site visits, projects, and in-person team collaboration as needed.

Who You Are 

• Qualified candidates should have previous experience performing natural resource-related evaluations, technical studies, analyses and tasks requiring knowledge based on education and at least two years of professional experience. 
• Previous construction compliance monitoring experience required.
• Qualified candidates must demonstrate the ability to perform all aspects of biological monitoring on small to large, complex construction projects. Some night and/or weekend work may be assigned. General experience with wildlife and vegetation species from the geographic area of work: California Central Valley and San Francisco Bay Area.
• Qualified candidates must have experience surveying and monitoring CA nesting birds. 
• Preference given to candidates with direct experience surveying, handling, and monitoring for, or with monitoring approvals by state and federal agencies for one or more of the following species: San Joaquin kit fox, California tiger salamander, California red-legged frog, northwestern pond turtle, San Francisco garter snake, giant garter snake, California black rail, western burrowing owl, western spadefoot, vernal pool brachiopods, Swainson’s hawk and/or other nesting birds, Crotch’s bumble bee, and bats.
• You enjoy fieldwork and can walk long distances carrying a backpack; and are able to lift at least 50 pounds. You are confident working outside, in remote and rural settings, as well as in urban environments. Physical outdoor work may include, but may not be limited to, work in all types of weather, traversing uneven ground and sometimes steep terrain in vegetated environments, agricultural fields, arid lands, and along stream banks. You may be exposed to inclement weather and uncomfortable working conditions. Some early morning, late night and/or weekend work, as well as long hours may be required
• Must possess a valid driver’s license and have own transportation to project sites
• Must have a smart phone with sufficient data plan to collect necessary data on-site

What You Will Do for ESA

• Perform biological compliance monitoring and reporting at active construction sites to ensure conformance with environmental/permit requirements
• Conduct special-status species surveys and nesting bird surveys
• Construction compliance monitoring
• Identify and may relocate sensitive species, when needed and if agency-approved
• Effectively communicate with senior ESA staff, construction crews, project personnel, and project management staff
• Take initiative and contribute to a respectful, feedback-driven team culture
• Maintain daily written monitoring and inspection logs, including utilizing electronic data collection tools, such as Fulcrum and Trello
• Enter data into an on-line GIS mapping application, such as Fieldmaps, Collector, Survey 123
• Deliver worker environmental awareness training to on-site staff
• Comply with all safety requirements and policies
• Field work outside, potentially in remote or rural settings, as well as in urban environments.
• Desk-based data processing, technical evaluations, and a range of client deliverables
• Training/mentoring early career biologists
• Other ad hoc tasks as needed

What’s Special About Our Biology Team

Our Biology Team includes biologists, restoration ecologists, permitting specialists, conservation biologists, and environmental scientists that provide expertise for many municipalities throughout California. Our work matters because it helps communities shape a positive future for their citizens in balance with conserving our state’s sensitive natural resources. We value creative thinking, teamwork, and multi-disciplinary and cross-disciplinary engagement and integration. 

We encourage you to read about some of the exciting projects we have recently completed. 

What’s Special About ESA

Joining ESA means becoming part of a close-knit team of environmental professionals who contribute to outstanding projects, improve environmental stewardship, and advance a more sustainable and resilient future for our communities and wild places.

At ESA, we provide benefits such as medical, dental, and vision insurance (paid at 70% for you AND your family), annual allocations of company share through our ESOP, a 401(k) plan with company match, and paid vacation, sick leave, and holidays, to name a few.

We also provide specific programs whether you want to further your technical expertise, sharpen your business acumen, or help lead the next generation of employee-owners. We want to support you in reaching your career goals through tuition reimbursement, professional development bonuses, and attendance at conferences.

The Team

The Biohub in New York is an independent nonprofit research institute that brings together three powerhouse universities - Columbia University, The Rockefeller University, and Yale University - into a single collaborative technology and discovery engine. Biohub itself supports some of the brightest, boldest engineers, data scientists, and biomedical researchers to investigate the fundamental mechanisms underlying disease and develop new technologies that will lead to actionable diagnostics and effective therapies. We are guided by our values of scholarly excellence; disruptive innovation; hands-on engineering/hacking/building; partnership and collaboration; open communication and respect; inclusiveness; and opportunity for all.

Our Vision                                                                     

• We pursue large scientific challenges that cannot be pursued in conventional environments
• We enable individual investigators to pursue their riskiest and most innovative ideas
• The technologies developed at Biohub facilitate research by scientists and clinicians at our home institutions and beyond

Diversity of thought, ideas, and perspectives are at the heart of Biohub and enable disruptive innovation and scholarly excellence. We are committed to cultivating an organization where all colleagues feel inspired and know their work makes an important contribution.

The Opportunity

The van der Stegen Lab at Biohub NY studies human immune cell development from induced pluripotent stem cells and designs engineering strategies to harness immune cells for therapeutic applications. We are looking for a Computational Biologist to join our team to further expand our evaluation of immune cell lineage commitment, function and how genetic engineering strategies can affect those. 

The Computational Biologist will possess deep expertise in the analysis of single cell transcriptional data, including developmental trajectory analysis, and ideally also have experience with proteomics datasets. They have an interest in hematopoiesis and immune cell biology and can demonstrate the intention to apply state-of-the-art analysis tools through close collaboration with the data science team at Biohub.

What You'll Do

• Implement and create analytical pipelines for transcriptomics, including chemical and/or genetic perturbations, and multi-omic datasets
• Support immunologists in experimental design for transcriptomic and multi-omic analysis
• Support immunologist in the experimental design of CRISPR screens
• Analyze scRNAseq, CITE-seq, scATACseq, TCR/BCRseq and Mass Spectrometry datasets
• Incorporate publicly available datasets with in-house generated datasets
• Support new hypothesis generation 
• Present research findings in academic journals and conferences

What You'll Bring

• PhD degree in computational biology, systems biology, immunology, bioengineering or a related field.
• Experience working with hematopoiesis-, immunology- or developmental biology-related datasets
• Experience analyzing data from perturbational screens (e.g. perturb-seq)
• At least 4 years of programming experience in R and/or Python
• Ability to communicate effectively with wet-lab biologists
• Expertise in bioinformatics including computational pipelines for analyzing bulk and single-cell genomics (Scanpy, Seurat, etc)
• Ability to work efficiently in HPC or cloud compute (e.g. AWS) environments
• Strong written and verbal communication skills
• Experience in presenting research findings
• Track record of publishing in peer-reviewed journals 
• 3+ years of experience with large scale immune data (single cell sequencing, T and B cell receptor profiling, mass spectrometry)
• Demonstrated ability to deliver multiple large biological data products, deploying QC best practices
• Experience with proteomic analysis datasets including flow cytometry and mass spectrometry
• Experience with spatial transcriptomics
• Familiar with metabolomic datasets
• Committed to writing well-commented code and documentation, and familiarity with coding best practices (i.e. version control, code review)

Compensation

The New York City, NY base pay range for a new hire in this role is $153,000 - $210,100. New hires are typically hired into the lower portion of the range, enabling employee growth in the range over time. Actual placement in range is based on job-related skills and experience, as evaluated throughout the interview process. 

This position may be eligible to participate in Biohub's discretionary annual performance bonus program. Bonus eligibility and targets are determined in accordance with Biohub's total rewards philosophy and may vary by role.

Better Together

As we grow, we’re excited to strengthen in-person connections and cultivate a collaborative, team-oriented environment. This role is a hybrid position requiring you to be onsite for at least 60% of the working month, approximately 3 days a week, with specific in-office days determined by the team’s manager. The exact schedule will be at the hiring manager's discretion and communicated during the interview process.

Benefits for the Whole You 

We’re thankful to have an incredible team behind our work. To honor their commitment, we offer a wide range of benefits to support the people who make all we do possible. 

• Provides a generous employer match on employee 401(k) contributions to support planning for the future.
• Paid time off to volunteer at an organization of your choice. 
• Funding for select family-forming benefits. 
• Relocation support for employees who need assistance moving

If you’re interested in a role but your previous experience doesn’t perfectly align with each qualification in the job description, we still encourage you to apply as you may be the perfect fit for this or another role.

#LI-Onsite

The Team

Our decoding inflammation team builds tools to enable precise molecular-level measurements of inflammation within human tissues in real time, and develop proactive, early interventions that can be deployed when inflammation — which underlies the most significant causes of death worldwide — first flares in the body. You can learn more about our work here. 

Our team collaborates with three powerhouse universities - Northwestern University, the University of Chicago, and the University of Illinois Urbana-Champaign - to develop first-in-class technologies and make breakthroughs.

Our Vision

• Pursue large scientific challenges that cannot be pursued in conventional environments
• Enable individual investigators to pursue their riskiest and most innovative ideas
• Facilitate research by scientists and clinicians at our home institutions and beyond

We are a team of passionate individuals powered by technology, guided by scientific research, and driven by collaboration, working toward a mission to cure or prevent all disease.

The Opportunity

Biohub is seeking a Computational Biologist to join our interdisciplinary AI/ML team within the Virtual Immune System initiative. This is a hands-on research role focused on building and evaluating lab-in-the-loop experimental systems and closing the cycle between computational models of immune cell behavior and wet-lab validation. The ideal candidate brings strong biological intuition, computational rigor, and experience applying machine learning to genomics or perturbation biology.

You will work at the intersection of foundation models, reasoning systems, and experimental immunology — developing frameworks for how these tools can be integrated into experimental workflows. This means defining what questions are addressable, designing experiments that stress-test model predictions, guiding analysis, and evaluating performance across the loop. The environment is highly collaborative and interdisciplinary, spanning immunology, automation engineering, and machine learning, with direct applications to human health and disease.

What You'll Do

• Design computationally-guided experiments leveraging reasoning models, foundation models, and automated lab infrastructure to address open questions in immunology and inflammation.
• Partner with experimental scientists, automation engineers, and AI/ML researchers to define addressable biological questions, close the loop between model predictions and wet-lab validation, and iterate on experimental strategy.
• Develop and document best practices for designing experimental workflows, including data acquisition strategy, analysis pipelines, and frameworks for iterative refinement across the loop.
• Critically evaluate model predictions by stress-testing outputs against external datasets, known biology, and expert intuition — identifying failure modes and feeding improvements back into model development.
• Contribute to publications, open-source tools, and translational applications that advance the field of computationally driven immune system modeling.

What You'll Bring

• PhD in Immunology, Computer Science/Statistics, Computational Biology/Genomics, or a related field.
• 3 to 5 years of experience of applying machine learning and computational approaches to biological problems, particularly in genomics or genetic perturbation screening (e.g., CRISPR-based screens, Perturb-seq).
• Hands-on experience with foundation models, LLMs, or reasoning models and a drive to rigorously evaluate where they do and don't work when applied to biological questions.
• Strong biological intuition and a clear scientific point of view — able to identify which questions are tractable, design experiments that test model predictions, and know when results don't pass the smell test.
• Strong programming and data skills (Python preferred), with an emphasis on reproducibility and clear documentation.
• Effective cross-domain communicator with experience working alongside experimentalists, engineers, or other non-computational collaborators to translate between domains and validate computational predictions.

Compensation

The Chicago, IL base pay range for a new hire in this role is $162,000.00 - $202,000.00. New hires are typically hired into the lower portion of the range, enabling employee growth in the range over time. Actual placement in range is based on job-related skills and experience, as evaluated throughout the interview process. 

This position may be eligible to participate in Biohub's discretionary annual performance bonus program. Bonus eligibility and targets are determined in accordance with Biohub's total rewards philosophy and may vary by role.

Benefits for the Whole You 

We’re thankful to have an incredible team behind our work. To honor their commitment, we offer a wide range of benefits to support the people who make all we do possible. 

• Provides a generous employer match on employee 401(k) contributions to support planning for the future.
• Paid time off to volunteer at an organization of your choice. 
• Funding for select family-forming benefits. 
• Relocation support for employees who need assistance moving

If you’re interested in a role but your previous experience doesn’t perfectly align with each qualification in the job description, we still encourage you to apply as you may be the perfect fit for this or another role.

#LI-Onsite

The Impact You’ll Make

As a key member of Recursion's partnership-facing data science team, you will be at the forefront of reimagining drug discovery from first principles using Recursion’s massive data and compute capabilities. As senior computational biologist, you will be supporting a portfolio of partnership preclinical drug programs and be responsible for designing and executing analyses to support target nomination, validation, and early programs in neuroscience diseases.

You will integrate layers of Recursion platform data (phenomics, transcriptomics, proteomics, etc) to validate the link between target and disease biology and to propose targets and early programs in novel areas of neuroscience. You will partner with biologists and medicinal chemists to build supporting data packets for targets from our phenomic maps, target screens, and partnered patient data sets. You will also collaborate with computational scientists from across the organization to develop, deploy, and scale novel approaches to: 1) translational validation in hit to lead, 2) mechanism-of-action identification/de-risking, and 3) build evidence for patient connectivity to match the targets we are validating and medicines we are creating to the patients who need them.  

In this role, you will:

• Deliver biological insights on therapeutic candidates and disease biology from the analysis of high-dimensional (phenomics, transcriptomics, proteomics, patient-derived) datasets that support clinical development planning
• Evaluate the biological and molecular evidence for therapeutic hypotheses and accelerate drug program progression into the clinic
• Synthesize diverse datasets (internal and external) to generate and evaluate hypotheses for drug discovery, biomarker development, mechanism of action and target population identification
• Present data analysis to decision makers and stakeholders in a clear and compelling way that drives toward getting medicines to patients
• Assess new data sources, develop and scale new analysis methods, and support key program decisions with the ultimate goal of bringing life-changing therapies to patients at unprecedented speed
• Industrialize analysis approaches to not only solve for the current project, but also to accelerate future projects and scale the impact that we can have
• Collaborate cross-functionally with Recursion’s data science, biology, medicinal chemistry, and  platform, teams to further advance Recursion’s ability to interpret and translate large-scale data assets into therapeutic programs

The Team You’ll Join 

Our group is a bold, agile, diverse collective of computational drug discovery scientists and data scientists deeply focused on the singular goal of bringing new therapeutics into the clinic at an accelerated pace. We are a computational group that spans precision oncology, neuroscience, and I&I (immunology and inflammation), and focuses on advancing novel, targeted therapies for these disease areas. We partner closely with our biologists and medicinal chemists to design and execute impactful and decisional data analysis for multiple programs. We are responsible for data strategy across the portfolio and supported by computational leadership in designing scalable and reproducible experiments that serve to advance multiple programs within the portfolio. 

Our team collaborates extensively with computational biologists in other therapeutic areas (immunology, oncology, etc.) as well as data scientists and engineers from our core platform teams to provide a strong network of feedback and support. 

The Experience You’ll Need

• PhD in a relevant field (computational biology, systems biology, bioinformatics, neuroscience, etc.) with a very strong computational focus and 5+ years of experience in biotech or pharma industry OR MS in a relevant field
• Experience applying computational methods (including probabilistic, statistical, and/or machine learning techniques) to analyze and integrate matched human clinical and molecular data in a high-level programming language such as Python or R
• Deep expertise in the analysis and data integration of one or more ‘omics data modalities (phenomics, transcriptomics, proteomics, genomics) and/or human clinical data
• Exceptional data visualization skills
• Excellent cross-functional communication skills, including an ability to explain complex scientific concepts to a variety of audiences using a combination of plots, documents, and presentations

Nice To Have:

• Strong understanding of patient genetics and historical druggability of disease-relevant pathways,  including experience working with patient data
• Experience in efficiently advancing drug programs from proof of concept and into clinical development
• Experience with neuroscience clinical trial biomarker analysis
• Experience working as part of partnerships or client facing (consulting) teams

Working Location & Compensation:

This is an office-based, hybrid role in either our Salt Lake City or New York City offices. Employees are expected to work in the office at least 50% of the time.

At Recursion, we believe that every employee should be compensated fairly. Based on the skill and level of experience required for this role, the estimated current annual base range for this role is $200,600 to $253,100. You will also be eligible for an annual bonus and equity compensation, as well as a comprehensive benefits package. 

#LI-EP1

The Impact You’ll Make

As a computational biology specialist on our Target ID team, you will be at the forefront of transitioning Recursion to its next era of drug discovery. You will serve as a critical biological anchor for a highly technical data science team building the next generation of our target discovery pipelines.

The team’s mission is to identify novel therapeutic targets at scale across the genome for hundreds of indications. You will have access to all of Recursion's data layers—including massive internal maps, functional genomics, and rich patient data (transcriptomics, genetics, and Real-World Data/EHR)—and will be tasked with proposing, piloting, and deploying new methods to integrate these datasets.

Crucially, you will leverage your biological subject matter expertise to orient and focus your data scientist and software engineer peers towards reliable and correct usage of biological data and feasible candidate programs. As we build out semi-automated and agentic tools (e.g., multi-agent LLM systems for portfolio oversight and target assessment), your deep real-world biology experience will guide the development of these tools, ensuring they are grounded in biological reality and translate to meaningful portfolio and patient impact.

The ideal candidate is a computational biology specialist with high fluency in data science tech stacks. You know how to build and evaluate predictive models and build agentic pipelines, and your differentiator is your deep understanding of patient-relevant datasets, disease biology, and target discovery.

In this role, you will:

• Discover & Evaluate: Propose and validate novel targets using deep integration of patient data (transcriptomics, population genetics, EHR, etc) and Recursion's internal multi-omic data layers.
• Guide & Automate: Collaborate closely with data scientists to build, refine, and guide semi-automated and agentic target discovery tools. You will ensure these tools are biologically sound and can scale to evaluate hypotheses across many indications spanning a wide range of therapeutic areas.
• Triangulate: Use advanced statistical methods (e.g., causal inference, survival modeling) to establish confident target-to-patient connections and define specific addressable patient populations for early pipeline programs.
• Bridge the Gap: Translate complex platform findings into disease-relevant applications, bridging the gap between high-dimensional data science output and actionable drug discovery insights.
• Present & Influence: Communicate complex biological rationale and data analyses to decision-makers and cross-functional stakeholders, driving data-backed "go/no-go" decisions in a two-stage target approval process.

The Team You’ll Join

Our group is a bold, agile, diverse collective of data scientists and computational biologists driving Recursion’s early portfolio strategy. We are focused on aggressively expanding our early-stage pipeline with highly validated, novel therapeutic targets. To achieve this, we prioritize defining specific patient populations and establishing clear, data-backed translational paths from day one of every new program.

Because this team is dominated by experts in traditional data science, AI/ML, and software engineering, your role is absolutely critical. You will provide the essential biological experience and subject matter expertise to improve and accelerate the work of your peers. Essential attributes for this role include a bold, execution-first attitude, high technical fluency to collaborate seamlessly on data-science-heavy codebases, and a passion for deploying rigorous science to develop life-changing medicines.

The Experience You’ll Need

• PhD in Computational Biology, Bioinformatics, Human Genetics, Systems Biology, or a closely related field with 3+ years of experience in the biotech or pharma industry OR MS in a relevant field and 5+ years of industry experience focusing on target ID or early drug discovery.
• Biological SME: Deep, real-world experience in target discovery, functional genomics, and understanding the druggability of disease-relevant pathways.
• Data Science Fluency: Highly proficient in Python and/or R, with a strong ability to seamlessly integrate into a data-science-heavy tech stack. Comfortable with modern software engineering practices, cloud computing, and machine learning concepts.
• Patient Data Expertise: Extensive experience working with "discovery-related" human data, particularly transcriptomics (bulk/single-cell), patient genetics/GWAS, and clinical/real-world data (e.g., EHR).
• Analytical Rigor: Experience applying advanced computational and statistical methods to establish biological causality (e.g., survival analysis, causal inference modeling).
• Excellent cross-functional communication skills, with a proven track record of upskilling peers in biological concepts and guiding technical teams toward translatable biological outcomes.

Nice To Have:

• Experience working with, prompting, or integrating Large Language Models (LLMs) and autonomous agentic workflows into scientific research.
• Familiarity with building or utilizing Knowledge Graphs for target identification.
• Experience working in the field of oncology or immunology.

Working Location & Compensation:

This is an office-based, hybrid position at our US headquarters located in Salt Lake City, Utah. Employees are expected to work in the office at least 50% of the time.

At Recursion, we believe that every employee should be compensated fairly. Based on the skill and level of experience required for this role, the estimated current annual base range for this role is $151,800 to $230,000. You will also be eligible for an annual bonus and equity compensation, as well as a comprehensive benefits package. 

#LI-EP1

tl;dr

General Proximity is a seed-stage startup developing the next generation of induced proximity medicines (IPMs). Our OmniTAC drug discovery engine furnishes molecules that co-opt existing cellular machinery to overcome therapeutic challenges, which have remained unapproachable to other modalities for decades.

We are seeking a first-rate chemical biologist to help us pioneer this uncharted frontier of drug discovery.

Our Story

A long-standing challenge in drug discovery is the development of molecules capable of modulating difficult or "undruggable" targets. Disease-causing proteins can be dysfunctional in many different ways, but our armamentarium for fixing them is quite limited. The most common mechanism of action for FDA-approved drugs is inhibition[1], but there are many other possible perturbation types whose potential remains unrealized.

General Proximity is a seed-stage drug discovery company developing a novel platform technology to solve this problem. We make bifunctional drugs that induce the modification of drug targets by existing cellular machinery (rather than through direct modulation by the drug, the classical approach).

Historically, the development of technologies that allow one to push new buttons in biology has been an incredibly fertile field for the discovery of new medicines[2, 3, 4], and our technology holds the same promise.

The Position

We are seeking an experienced chemical biologist with medicinal chemistry training to be a founding member of our Chemistry/Drug Discovery Team. In this position, you will work with both our Chemistry and Platform Teams in the development of our core drug discovery technology and the generation of a completely novel class of therapeutics.

Your responsibilities will include: supervising synthetic efforts with our CROs, designing, performing, and analyzing in cellulo assays, designing and optimizing first-in-class bifunctional molecules, collaborating with our Drug Discovery and IP team on patent applications, providing input for mechanistic studies on lead drug molecules, and spearheading forays into new disease areas.

About You

High Agency. Initiative, independence, and self-accountability are some of our most valued traits.

Enthusiastic. We love people who are excited about what they are doing and are generally attempting to build a high-energy team.

Intensity and Grit. Early-stage startups are hard. Drug discovery is doubly so. We are looking for candidates who have a demonstrated ability to stick with complex problems for the long haul, with a team that has your back along the way.

Prosocial. We are here to create life-saving medicines for the patients who need it most. You should be, too.

Qualifications & Nice-To-Haves

• PhD in Chemical Biology, Medicinal Chemistry, Pharmacology, or related field.
• Industry experience is desirable, but the ability to work hard and learn fast is more important to us.
• Deep understanding of small-molecule drug discovery and its relationship to human disease.
• Able to work fluently at the interface of chemistry and biology.
• Top-notch written and oral communication skills.

• Strong experience with:
  • Designing, synthesizing, and optimizing induced proximity medicines (e.g. PROTACs or other IPMs)
  • Contributing to hit-to-lead and lead optimization studies
  • Med-chem optimizations: SAR, PK/PD, strong understanding of DMPK
  • Experience with chemical biology techniques such as mammalian cell culture and cell-based assays (e.g., cytotoxicity assays, transfections, stable cell line generation, co-immunoprecipitation), and PPI assays (e.g., BRET, APEX/BioID, AlphaScreen)

• Nice to have:
  • Proficiency in HTS and phenotypic assay development
  • Proteomics experience: PTM analysis, chemo-proteomic target deconvolution, etc.
  • Computational or molecular dynamics drug discovery experience
  • DEL experience
  • Experience managing others, especially synthetic chemistry CRO teams
  • Prior experience on teams that have successfully advanced research to the clinic

Benefits

• Strong equity incentives. We are looking for candidates who will bring a strong sense of ownership to drive their project areas forward, and we believe that you deserve to be compensated accordingly.
• Top tier medical, dental, and vision coverage + One Medical membership.
• 401(k) retirement plans.
• Education and health/fitness incentive programs.
• Meditation retreats—do a ten-day Vipassana retreat without counting towards vacation days. 
• Reading budget! We will buy you books. 📚
• Located in the MBC BioLabs at 135 Mississippi Street, an entrepreneurial hub full of the best scientists and operators the Bay Area has to offer. Our lab is a very short walk from the 22nd St Caltrain Station and a number of wonderful restaurants and cafés.

About Us

Work Hard/Play Hard. We believe time is our most valuable commodity, so we strive to create a culture that reflects this. We won’t drag you through unnecessary meetings or email you at 7 PM on a Saturday. When we're at work, we're there to get things done, and when we're off, we're really off. 🌴

Strong Communication. We like well-written documents over PowerPoints, OKRs over vague mission statements, and weekly one-on-ones over yearly reviews.

Writing First. We have a "writing-first" culture. We believe that clarity of writing reflects clarity of thinking and that the benefits of well-written documentation in a scientific environment are innumerable: democratization of ideation and decision-making, increased reproducibility, quicker scaling and onboarding, and better company-wide alignment, to name a few.

Growth. As an early-stage startup, we value scientists with an independent, can-do attitude. The more hats you can wear, the better. Our job as employers is to put you in positive feedback loops so you can grow in the direction of your choosing.

Title and compensation commensurate with experience. Applications from candidates of diverse backgrounds, women, and members of underrepresented minority groups are particularly welcomed. We look forward to hearing from you. :)

More info at jobs.generalproximity.bio

Company overview:

Flagship Labs 109, Inc. (FL109) is a privately held, early-stage technology company pioneering the use of artificial intelligence, physics and hardware to transform the way we see biology. FL109 was conceived by Flagship Pioneering, which brings the courage, long-term vision, and resources needed to realize unreasonable results. Become part of our mission-driven team and help envision the future of science.

About the Role

The Director of Sales will be responsible for driving customer acquisition, building strategic partnerships, and delivering revenue growth across our VaaS, SaaS, and platform offerings.

This is a hands-on leadership role for a commercially fluent structural biologist or technical sales leader who can operate as both strategist and executor. You will own a defined bookings target, lead end-to-end customer engagement, and act as the commercial “mini-CEO” for client relationships.

In addition to revenue ownership, you will shape FL109’s market development and outreach strategy, from identifying and cultivating prospective customers to leading participation in key industry events and creating high-impact content that builds awareness and engagement.

This is a builder role: best suited for a commercially fluent leader who thrives on creating structure, establishing customer relationships, and developing scalable business systems in an emerging market.

Key Responsibilities

Revenue & Commercial Ownership

• Own and exceed annual bookings and revenue targets for FL109’s commercial offerings.
• Build and manage a qualified pipeline from prospecting through close, leveraging CRM data to ensure forecast accuracy.
• Hold pricing and commercial terms authority within defined guardrails; manage forecasts and deal reviews with leadership.
• Negotiate and structure agreements that create long-term value for customers and for FL109.
• Partner with Finance and Operations to align delivery plans with revenue recognition and margin goals.
• Report regularly on pipeline health, deal progress, and revenue performance to leadership.

Customer Acquisition & Partnership Development

• Identify, engage, and nurture new customers across pharma, biotech, and the Flagship ecosystem.
• Develop tailored account strategies to expand adoption and drive repeat business.
• Build and maintain trusted executive-level relationships with customer stakeholders.
• Represent FL109 externally at key meetings, conferences, and industry events.

Market Development & Outreach

• Develop and oversee FL109’s external engagement strategy, including targeted outreach, event participation, and partnership visibility.
• Partner with leadership and external vendors to execute campaigns, manage event logistics, and track lead conversion.
• Develop and maintain a calendar of high-impact scientific and commercial events aligned with FL109’s growth priorities.
• Contribute to content creation and thought leadership efforts that build FL109’s brand presence across industry channels and social media.
• Manage a modest budget for event participation and outbound initiatives, prioritizing efforts with the highest commercial impact.

Customer Insight & Market Feedback

• Capture key learnings from customer and partner engagements to refine FL109’s value proposition and go-to-market approach.
• Collaborate with the Product and AI teams to share structured insights that inform product strategy and prioritization.
• Represent customer perspectives in internal discussions to ensure solutions align with market needs.

Commercial Infrastructure

• Partner with a part-time CRM consultant to finalize implementation, ensure data integrity, and establish effective reporting.
• Own the commercial use and adoption of the CRM system to drive visibility, forecasting accuracy, and pipeline health.
• Define and track key growth metrics and reporting cadence for leadership review.

Cross-Functional Collaboration

• Partner with the Client Project Manager to ensure seamless delivery and high customer satisfaction.
• Contribute to pricing, go-to-market, and commercial strategy discussions.
• Work within established templates and tools for contracting, security documentation, and proposal development, with support from internal and external resources as needed.
• Serve as the internal advocate for customer success and external excellence.

Qualifications

• 8+ years of experience in commercial, BD, or sales leadership within life sciences, platform technologies, or capital equipment markets.
• Proven record of achieving or exceeding multi-million-dollar sales targets in complex technical environments.
• Experience leading cross-functional commercial efforts in a matrixed organization.
• Deep understanding of cryo-EM or adjacent analytical technologies preferred.
• Experience with outreach, event strategy, and business development in scientific or technology-driven markets.
• Strong negotiation, forecasting, and strategic account planning skills.
• Excellent communication and executive-level presentation abilities.
• Builder mindset: resourceful, analytical, and comfortable with ambiguity in early-stage environments.

About Flagship

Flagship Pioneering is a bioplatform innovation company that invents and builds platform companies, each with the potential for multiple products that transform human health or sustainability. Since its launch in 2000, Flagship has originated and fostered more than 100 scientific ventures, resulting in generation of over 500 patents, initiation of over 50 clinical trials for novel therapeutic agents and an aggregate value of more than $90 billion. Many of the companies Flagship has founded have addressed humanity’s most urgent challenges: vaccinating billions of people against COVID-19, curing intractable diseases, improving human health, preempting illness, and feeding the world by improving the resiliency and sustainability of agriculture. Flagship has been recognized twice on FORTUNE’s “Change the World” list, an annual ranking of companies that have made a positive social and environmental impact through activities that are part of their core business strategies and has been twice named to Fast Company’s annual list of the World’s Most Innovative Companies. Learn more about Flagship at www.flagshippioneering.com.

Flagship Pioneering is committed to equal employment opportunity regardless of race, color, ancestry, religion, sex, national origin, sexual orientation, age, citizenship, marital status, disability, gender identity or Veteran status.

At Flagship, we recognize there is no perfect candidate. If you have some of the experience listed above but not all, please apply anyway. Experience comes in many forms, skills are transferable, and passion goes a long way. We are dedicated to building diverse and inclusive teams and look forward to learning more about your unique background.

Recruitment & Staffing Agencies: Flagship Pioneering and its affiliated Flagship Lab companies (collectively, “FSP”) do not accept unsolicited resumes from any source other than candidates. The submission of unsolicited resumes by recruitment or staffing agencies to FSP or its employees is strictly prohibited unless contacted directly by Flagship Pioneering’s internal Talent Acquisition team. Any resume submitted by an agency in the absence of a signed agreement will automatically become the property of FSP, and FSP will not owe any referral or other fees with respect thereto.

The expected base salary range for the role is $100,000 to $140,000, with a target commission of $90,000 to $150,000, for a total on-target range of $230,000 to $290,000 OTE. Actual earnings will vary based on performance. Base salary for the role will depend on a number of factors, including a candidate’s qualifications, skills, competencies, and experience. Commission is earned based on defined performance metrics. Flagship Pioneering currently offers healthcare coverage, retirement benefits and a broad range of other benefits. Compensation and benefits information is based on Flagship Pioneering’s good faith estimate as of the date of publication and may be modified in the future.

What if… you could join an organization that creates, resources, and builds life sciences companies that invent breakthrough technologies in order to transform health care and sustainability?

Company Description

Expedition Medicines is a privately held, early-stage biotechnology company pioneering the emerging field of Protein Editing. At Expedition Medicines we create small molecules that edit protein structure and function to unlock presently undruggable targets and a broad array of therapeutic modalities. Our platform integrates novel small molecule chemistry and chemoproteomic discovery technologies with Machine Learning (ML) to enable generative design. Expedition Medicines is backed by Flagship Pioneering, bringing their courage, vision, and resources to guide Expedition Medicines from platform validation to patient impact. We are seeking collaborative, relentless problem solvers that share our passion for impact to join us! 

About the role:

The role of Senior/Principal Scientist, Structural Biologist will focus upon determination of protein-ligand complex structures by X-ray crystallography and cryo-EM.  The scientist in this position will be responsible for delivering structures and collaborating with project teams to enable structure-based drug design and elucidate the mechanism-of-action of small molecules. 

Candidate responsibilities:

• Design and execute structural biology strategy for one or more projects
• Oversee construct design, expression and purification of proteins for structure determination
• Develop and execute protocols to obtain high quality crystals for X-ray structures
• Develop and execute protocols for grid optimization, data collection, and data analysis for structure determination using cryo-EM
• Obtain and refine structures of protein-ligand complexes, communicate the results and collaborate with project teams to drive hit-to-lead and lead optimization
• Manage CROs for effective delivery of protein expression and structural biology services
• Expand our capabilities and serve as a trusted expert in structural biology

Qualifications:

• PhD/MS degree in structural biology, biochemistry, molecular biology, or a related field with at least 3 years of drug discovery experience in an industry setting
• In-depth knowledge and hands-on experience in X-ray crystallography and cryo-EM, including crystal optimization, grid preparation, data collection, data processing, structure refinement, and interpretation of protein structures
• Experience managing CROs for protein production and structural biology
• Excellent collaboration, communication, and organizational skills
• Strong desire to learn and implement new methods in protein biochemistry, biophysics, and structural biology
• Experience with biophysical methods (SPR, DSF, MST) or mass spectrometry (intact MS, peptide mapping, proteomics) is a plus

ABOUT FLAGSHIP PIONEERING

Flagship Pioneering invents and builds platform companies, each with the potential for multiple products that transform human health, sustainability and beyond. Since its launch in 2000, Flagship has originated more than 100 companies. Many of these companies have addressed humanity’s most urgent challenges: vaccinating billions of people against COVID-19, curing intractable diseases, improving human health, preempting illness, and feeding the world by improving the resiliency and sustainability of agriculture.  

Flagship has been recognized twice on FORTUNE’s “Change the World” list, an annual ranking of companies that have made a positive social and environmental impact through activities that are part of their core business strategies and has been twice named to Fast Company’s annual list of the World’s Most Innovative Companies. Learn more about Flagship at www.flagshippioneering.com.

At Flagship, we accept impossible missions to enable bigger leaps. Our core values guide us through uncertainty and toward lasting impact.

We are an equal opportunity employer. All qualified applicants will be considered for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, disability, protected veteran status, or any other characteristic protected by law.

We recognize that great candidates often bring unique strengths without fulfilling every qualification. If you have some of the experience listed above but not all, please apply anyway. We are dedicated to building diverse and inclusive teams and look forward to learning more about your background and interest in Flagship.

Recruitment & Staffing Agencies: Flagship Pioneering and its affiliated Flagship Lab companies (collectively, “FSP”) do not accept unsolicited resumes from any source other than candidates. The submission of unsolicited resumes by recruitment or staffing agencies to FSP or its employees is strictly prohibited unless contacted directly by Flagship Pioneering’s internal Talent Acquisition team. Any resume submitted by an agency in the absence of a signed agreement will automatically become the property of FSP, and FSP will not owe any referral or other fees with respect thereto.

The salary range for this role is $126,000 - $214,500. Compensation for the role will depend on a number of factors, including a candidate’s qualifications, skills, competencies, and experience. Expedition Medicines currently offers healthcare coverage, annual incentive program, retirement benefits and a broad range of other benefits. Compensation and benefits information is based on Expedition Medicines's good faith estimate as of the date of publication and may be modified in the future.

Vesalius Therapeutics is seeking a computational biologist with 5+ years of experience in high-dimensional data analysis to join our team. You will report to the Head of Data Science and develop and apply state-of-the-art statistical methods to deliver actionable insights from our population scale iPSC-based high-throughput phenotyping platform. You will bring a solid foundation in applied statistics; high-performance, scalable, and reproducible scientific code; and molecular, cell, or tissue biology. You will serve also as a subject matter expert on statistical analysis and software development, mentoring junior data scientists and advising stem cell scientists and biologists. You will work both independently and in matrixed teams with stem cell scientists, biologists, statistical geneticists, and machine learning scientists. This is the opportunity to redefine common diseases using genetic and phenotypic data at an unprecedented scale and make critical advances in developing new therapeutics to address unmet need!

What You’ll Do:

• Deliver biological insights into cellular networks, patient biomarkers, and iPSC-based physiological models and champion decisions and next steps
• Write and deploy high-performance code/pipelines for large-scale computation
• Identify relevant external data sets and new opportunities/needs for internal data generation
• Integrate closely with stem cell and biology teams on experimental design, hypothesis generation, and data analysis
• Provide technical expertise and mentorship on statistics and computation to junior data scientists and stem cell and biology teams
• Communicate to both technical and non-technical audiences clearly both orally and in writing

What You’ll Bring:

• PhD. in Statistics, Biostatistics, Computer Science, or Mathematics
• 5+ years of industry experience analyzing high-dimensional datasets
• Knowledge of quantitative genetics in human or model organisms a plus
• Demonstrated expertise in computation and biology supported by publications or presentations
• Demonstrated proficiency in a relevant programming language (Python, R, etc.) supported by a public Github repository
• Experience developing novel models, algorithms, or software implementations a plus
• Strong communication skills in writing and speaking

At Flagship, we accept impossible missions to enable bigger leaps. Our core values guide us through uncertainty and toward lasting impact.

We are an equal opportunity employer. All qualified applicants will be considered for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, disability, protected veteran status, or any other characteristic protected by law.

We recognize that great candidates often bring unique strengths without fulfilling every qualification. If you have some of the experience listed above but not all, please apply anyway. We are dedicated to building diverse and inclusive teams and look forward to learning more about your background and interest in Flagship.

Recruitment & Staffing Agencies: Flagship Pioneering and its affiliated Flagship Lab companies (collectively, “FSP”) do not accept unsolicited resumes from any source other than candidates. The submission of unsolicited resumes by recruitment or staffing agencies to FSP or its employees is strictly prohibited unless contacted directly by Flagship Pioneering’s internal Talent Acquisition team. Any resume submitted by an agency in the absence of a signed agreement will automatically become the property of FSP, and FSP will not owe any referral or other fees with respect thereto.

The salary range for this role is $146,000 - $209,000. Compensation for the role will depend on a number of factors, including a candidate’s qualifications, skills, competencies, and experience. Vesalius Therapeutics currently offers healthcare coverage, annual incentive program, retirement benefits and a broad range of other benefits. Compensation and benefits information is based on Vesalius Therapeutics's good faith estimate as of the date of publication and may be modified in the future.

Vesalius Therapeutics is seeking a computational biologist with 5+ years of experience in high-dimensional data analysis to join our team. You will report to the Head of Data Science and develop and apply state-of-the-art statistical methods to deliver actionable insights from our population scale iPSC-based high-throughput phenotyping platform. You will bring a solid foundation in applied statistics; high-performance, scalable, and reproducible scientific code; and molecular, cell, or tissue biology. You will serve also as a subject matter expert on statistical analysis and software development, mentoring junior data scientists and advising stem cell scientists and biologists. You will work both independently and in matrixed teams with stem cell scientists, biologists, statistical geneticists, and machine learning scientists. This is the opportunity to redefine common diseases using genetic and phenotypic data at an unprecedented scale and make critical advances in developing new therapeutics to address unmet need!

What You’ll Do:

• Deliver biological insights into cellular networks, patient biomarkers, and iPSC-based physiological models and champion decisions and next steps
• Write and deploy high-performance code/pipelines for large-scale computation
• Identify relevant external data sets and new opportunities/needs for internal data generation
• Integrate closely with stem cell and biology teams on experimental design, hypothesis generation, and data analysis
• Provide technical expertise and mentorship on statistics and computation to junior data scientists and stem cell and biology teams
• Communicate to both technical and non-technical audiences clearly both orally and in writing

What You’ll Bring:

• PhD. in Statistics, Biostatistics, Computer Science, or Mathematics
• 5+ years of industry experience analyzing high-dimensional datasets
• Knowledge of quantitative genetics in human or model organisms a plus
• Demonstrated expertise in computation and biology supported by publications or presentations
• Demonstrated proficiency in a relevant programming language (Python, R, etc.) supported by a public Github repository
• Experience developing novel models, algorithms, or software implementations a plus
• Strong communication skills in writing and speaking

At Flagship, we accept impossible missions to enable bigger leaps. Our core values guide us through uncertainty and toward lasting impact.

We are an equal opportunity employer. All qualified applicants will be considered for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, disability, protected veteran status, or any other characteristic protected by law.

We recognize that great candidates often bring unique strengths without fulfilling every qualification. If you have some of the experience listed above but not all, please apply anyway. We are dedicated to building diverse and inclusive teams and look forward to learning more about your background and interest in Flagship.

Recruitment & Staffing Agencies: Flagship Pioneering and its affiliated Flagship Lab companies (collectively, “FSP”) do not accept unsolicited resumes from any source other than candidates. The submission of unsolicited resumes by recruitment or staffing agencies to FSP or its employees is strictly prohibited unless contacted directly by Flagship Pioneering’s internal Talent Acquisition team. Any resume submitted by an agency in the absence of a signed agreement will automatically become the property of FSP, and FSP will not owe any referral or other fees with respect thereto.

The salary range for this role is $146,000 - $209,000. Compensation for the role will depend on a number of factors, including a candidate’s qualifications, skills, competencies, and experience. Vesalius Therapeutics currently offers healthcare coverage, annual incentive program, retirement benefits and a broad range of other benefits. Compensation and benefits information is based on Vesalius Therapeutics's good faith estimate as of the date of publication and may be modified in the future.

At Personalis, we are transforming the active management of cancer through breakthrough personalized testing. We aim to drive a new paradigm for cancer management, guiding care from biopsy through the life of the patient. Our highly sensitive assays combine tumor-and-normal profiling with proprietary algorithms to deliver advanced insights even as cancer evolves over time. Our products are designed to detect minimal residual disease (MRD) and recurrence at the earliest timepoints, enable selection of targeted therapies based on ultra-comprehensive genomic profiling, and enhance biomarker strategy for drug development. Personalis is based in Fremont, California.

Summary:

A CLS Supervisor performs and reports on clinical laboratory testing that aids physicians in diagnosing and treating patients. A key part of the role is supervising team members and ensuring that all laboratory procedures are followed for specimen handling, next-generation sequencing (NGS) processes, test analyses, and the accurate maintenance of patient records.

In our lab, we foster a positive, friendly, and team-based environment. We all pitch in to achieve our common goals and support each other. You'll work in a dynamic atmosphere, gaining hands-on experience at multiple benches, including extractions, library preparation, and sequencing. You'll also partner with our lab assistants to coordinate pre-analytical and post-analytical tasks.

Available Shifts:

• Sun - Thu, 10:00pm - 6:30am

Responsibilities: 

• Perform and report clinical laboratory testing on patient samples to aid physicians diagnose and treat patients. This includes the following areas:
• Extractions
• Library Preparation
• Enrichments
• Sequencing
• Handle and process all patient specimens according to laboratory procedures, ensuring accurate and timely record-keeping and reporting of results.
• Select, implement, and evaluate quality control materials for statistical process control of laboratory assays.
• Troubleshoot assays and equipment when quality control materials fail to perform as expected.
• Document all corrective actions taken when test systems deviate from established performance specifications.
• Assist in audits by regulatory bodies like CAP and external customers.
• Participate in activities that support the laboratory's necessary licensure, including quality management and on-site inspections.
• Identify and correct problems that may negatively affect test performance or result reporting. If a problem cannot be immediately corrected, notify a supervisor, clinical consultant, or director.
• Train other CLS and lab personnel on laboratory methods.
• Monitor the activities of non-licensed staff.
• Provide guidance to team members on troubleshooting and deviation investigations.
• Assist in assay development activities.
• Demonstrate strong analytical skills and independent critical thinking.
• Apply technical and functional knowledge to help the team meet its goals.
• Work independently to identify and resolve complex, open-ended problems.

Requirements:

• Education: Bachelor's degree, preferably in sciences or related discipline.
• Licensure: Valid California Clinical Laboratory Scientist (CLS) or Clinical Genetic Molecular Biologist Scientist (CGMBS) license.
• Experience: At least four years of CLS experience in a clinical laboratory environment. Minimum 1 year experience in a Lead role is required.
• Preferred Skills: Experience with manual DNA/RNA extractions, manual library preparation, and automated liquid handlers.

The hiring range for this position is $72.10 to $81.70 per hour plus applicable shift differential. The offer will take into account internal equity and also may vary depending on the candidate’s geographic region, job-related knowledge, skills, and experience among other factors. Our full-time regular positions also include an annual performance-based bonus (or a sales incentive plan) and long-term incentive units (equity) provided as part of our compensation package, in addition to a full range of medical, financial, and/or other benefits, dependent on the level and position offered.

Personalis is an equal opportunity employer and is committed to the full inclusion of all individuals. As part of this commitment, Personalis will ensure that persons with disabilities are provided with reasonable accommodations. If you need an accommodation to participate in the job application or interview process, to perform essential job functions, and/or to receive other benefits and privileges of employment, please let your recruiter know, if/when they contact you.

Protecting Our Candidates: At Personalis, we value your security. Please note that all official correspondence from our team will come exclusively from @personalis.com email addresses. We will never ask for personal financial information or conduct interviews over text or chat platforms. If you receive a suspicious request, it is likely a scam. We are committed to a safe recruitment experience and actively work with authorities to investigate and prosecute cyber crimes targeting our community.

Personalis offers a competitive compensation package and benefits including medical, dental, vision, 401(k) match, ESPP, tuition reimbursement, sick/vacation time, commuter benefits/ EV charging stations, onsite gym, and wellness benefits. (For US only, benefits in other countries may vary.)

#LI-KK1 #LI-Onsite

September 24, 2025

Position:   
Senior Computational Biologist/ ML Scientist 

Company Overview:   
At Kernal Bio, we engineer human cells inside the body using selective mRNA-LNP technology to treat cancer and autoimmune diseases. Our AI-designed mRNAs, delivered via antibody-decorated lipid nanoparticles (LNPs), ensure precise targeting and minimize off-target effects. Our KR-402 program focuses on hematological malignancies and autoimmune disorders, achieving >90% in vivo delivery efficiency with T-cell-targeted LNPs. The KR-335 program, targeting solid tumors resistant to standard immunotherapies, shows a 100x therapeutic index with strong efficacy and tolerability in preclinical models, including mice and non-human primates.

With roots at MIT, Harvard, Merck, and BMS, our management team has spearheaded the development of three FDA-approved therapies and holds over 120 patents. Based in Cambridge, MA, and backed by Hummingbird Ventures, Amgen Ventures, NVIDIA, and NASA, Kernal Bio is revolutionizing mRNA therapeutics by leveraging AI to deliver precision treatments within the body. 

Job Summary 

Senior Computational Biologist/ ML Scientist 
We are seeking a Senior Computational Biologist to join our dynamic R&D team and spearhead our drug discovery efforts. This is a chance to move beyond routine data analysis and creatively apply advanced computational methods to solve complex biological challenges. You will be a key driver in designing next generation mRNA therapeutics, directly impacting our pipeline and scientific strategy.

The Role
As a core member of our research group, you will leverage your expertise to extract meaningful insights from diverse datasets. Your primary focus will be on applying sophisticated data science and machine learning techniques to biological questions. You’ll collaborate closely with diverse cross-functional teams, including our wet lab scientists, synthetic biology, and formulation teams, acting as a bridge between data and discovery.

Key responsibilities include:

Data Analysis & Modeling: Design and execute rigorous statistical and computational analyses by integrating and analyzing diverse omics datasets, including genomics, transcriptomics, proteomics, and single-cell sequencing data. You will also be responsible for developing, training, and deploying novel AI/machine learning models to predict biological outcomes and accelerate drug discovery.

High-Performance Computing: Efficiently manage and scale computational workloads by leveraging cloud computing platforms and utilizing NVIDIA GPU-accelerated computing for data processing and model training.

Scientific Communication: Prepare scientific manuscripts, contribute to intellectual property filings, and present your findings at leading scientific conferences and internal meetings.

Documentation & Workflow: Meticulously document all computational workflows, experimental results, and analyses in an Electronic Lab Notebook (ELN) such as Benchling and maintain rigorous version control and facilitate collaborative code development using platforms like GitHub.

Mentorship: Guide and mentor junior team members, sharing your knowledge of best practices in computational analysis and scientific inquiry.

Who We’re Looking For
We are looking for a creative and detail-oriented scientist with a proven track record. You should have a Ph.D. in Computational Biology, Bioinformatics, or a related field, along with a minimum of 3 years of experience in the biopharmaceutical industry.

You are a master of your craft with:

Deep Expertise: A strong background in the analysis of high-throughput biological data, including genomics, transcriptomics, proteomics, and single-cell sequencing.

Modern Skill Set: Experience applying machine learning and AI, with a solid theoretical grasp of algorithms like gradient descent, Bayesian optimization, and other heuristic search methods. Proficiency with large language models (LLMs) is a significant plus.

Accelerated Computing: Hands-on experience with NVIDIA GPU-accelerated computing is highly valued. Familiarity with CUDA, cuDNN, or NVIDIA Clara for bioinformatics applications will set you apart.

Programming Prowess: Exceptional fluency in Python and experience with workflow management systems, with a strong emphasis on version control using Git/GitHub.

Cloud Computing: Hands-on experience with at least one major cloud platform (AWS, Azure, or Google Cloud).

Intellectual Curiosity: A creative, out-of-the-box thinker who is eager to learn new methods and tackle complex problems head-on.

Collaborative Spirit: Excellent communication and time-management skills, with the ability to manage multiple projects and work effectively within cross-functional teams.

Benefits:

• Competitive 401(k)   
• Highly competitive healthcare coverage (PPO/HMO)
• Free parking, a monthly subway pass, or a subsidized commuter rail pass  
• Free Bluebike Membership
• Gym Membership Support   
• Flexible Spending Account 
• Paid parental leave, family caregiver leave, and medical leave  
• Paid life insurance coverage 
• On-site cafeteria  
• Competitive vacation and sick days per year 

Kernal provides a diverse work environment and is committed to equal employment opportunities for all its employees and qualified applicants. We do not discriminate in employment practices for the race, color, national origin, age, gender, sexual orientation, marital or veteran status, religion, disability, or any other legally protected status. Kernal Bio will make reasonable accommodations for qualified individuals with known disabilities in accordance with applicable law.

POSITION SUMMARY:

The Manager, Clinical Lab is a key leader in Natera’s lab operations who oversees and directs the development, planning, implementation and maintenance of manufacturing methods, processes and operations for new or existing products and technologies.  The Manager works closely with groups to ensure strict compliance with good manufacturing practices and CLIA/CAP guidelines at all times.  Ensures the effective use of materials, equipment and employees in producing quality products.  Monitor and control staffing / labor, capital expenditures, and manufacturing performance.  Develops budget and monitors expenditures.  Formulates and recommends manufacturing policies, procedures and programs.  Selects, develops and evaluates line-management to ensure the efficient operation of the function.

PRIMARY RESPONSIBILITIES:

• Under the direction of Senior lab leadership, and in close collaboration with other Laboratory leadership, this individual provides operational and strategic leadership to laboratory products assigned to the individual.

• Generates and routinely provides executive-level production/departmental summaries.

• Monitors workflow and ensures production goals and deadlines are met (e.g. TAT, SLA)

• Engages in future planning and scales employees and equipment appropriately

• Gathers and monitors metrics on production deadlines, efficiency, scrap waste, and error rates Monitors the quality control/assurance programs, test results, and equipment (if applicable)

• Uses metrics in decision-making and to drive changes across the team (e.g. cost reduction, quality improvement)

• Manages sufficient headcount levels to meet production goals by proactively driving the interview process and managing employee PTO and overtime when necessary.

• Refines current lab process through continuous improvement projects.

• Oversees team-specific lab operations.

• Go-to person when Senior lab leadership is not present; go-to person for knowledge of process and product.

• Responsible for seamless transition of automation and test improvement/additions into a production workflow

• Analyzes and troubleshoots lab processing errors; provides recommendations on how to proceed to lab director, scientists, and statisticians as necessary

• Supports Supervisors in the closeout of NCRs.

• Responsible for the initiation and closeout of CAPAs in a timely manner.

• Ensures departmental lab compliance for regulatory bodies

• Ensures tests are being completed according to approved procedures.

• Maintains an organized, safe, and efficient work area for the team at all times.

• Actively interacts with interdepartmental teams such as OPS, Accessioning, Engineering, Stats, R&D, and Support.

• Handle employee issues: complaints, disciplinary actions, etc. Collaborates with Senior Manager and/or Human Resources to resolve issues. • Knows and is ready to explain Natera’s core values. Explains (as much as possible) reasoning behind instructions/processes given/changes that are made. If necessary, explains to the team why certain ideas cannot be implemented effectively. Meets regularly with Supervisors to discuss goals and progress.

• Performs routine skip-levels with individual team members.

• Responsible for performance review of direct reports and overseeing performance review of the entire staff.

• Plans and leads team meetings • Develops high-performing employees by providing them with learning opportunities, cross-training opportunities, and new challenges whenever possible.

• Recognizes and rewards talent through merit reviews, promotions, and recognition programs

• Adheres to Departmental Expectations • Manages the training program for direct reports.

• Notifies management of all requirements for tools, supplies, etc.

• Receives assignments in the form of objectives and determines how to use resources to meet schedules and goals.

• Provides guidance to subordinates within the latitude of established company policies. Recommends changes to policies and establishes procedures that affect immediate organization(s).

• Manages, perhaps through subordinate supervisors, the coordination of the activities of a section or department with responsibility for results, including costs, methods and staffing. In some instances this manager may be responsible for a functional area and not have any subordinate employees.

QUALIFICATIONS:

• BS/BA degree in Biological Sciences, related field, or equivalent

• A minimum of 3+ years of relevant leadership experience and/or effectively managing a team preferred

• A minimum of 5+ years of industry-related experience preferred

• Current ASCP board certification in Medical Technology or California State CLS or CGMBS license (Clinical Genetics Molecular Biologist Scientist) is required

KNOWLEDGE, SKILLS, AND ABILITIES:  

• Exceptional multi-tasking, organizational, and communication skills.

• Excellent computer skills, including MS Excel.

• Able to be detailed oriented and can organize, prioritize.

• Strong problem-solving skills.

• Independent self-starter comfortable working in teams at all levels

• Experience in building and managing a high performing group of engaged and motivated employees

• Experience with working on a Laboratory Operations floor

• Knowledge and experience with Lean Six Sigma concepts and tools

• Manufacturing/Engineering experience preferred

Associate/Assistant Laboratory Director - Organ Health (San Carlos) 

POSITION SUMMARY

As an Associate Laboratory Director, you have clinical oversight of Natera’s laboratory testing.  You ensure that testing is properly performed, and applicable regulatory standards are met. You are accountable for ensuring that laboratory testing processes consistently provide accurate and reliable patient test results.

PRIMARY RESPONSIBILITIES:

• Review and approve test reports for a variety of clinical molecular/cytogenetic results, including cfDNA testing, and germline testing performed across Natera’s technology platforms.
• Oversee the review and interpretation of genetic testing results and associated variant or analyte data in the context of medical literature, databases and other references, along with relevant patient clinical data.
• Provide technical and clinical support for laboratory staff, genetic counselors, and other clinical personnel.
• Set standards for laboratory testing and acceptable levels of analytic performance and ensure these are maintained.         
• Analyze laboratory and clinical data, and contribute to or write publications for high-quality scientific journals.

May serve as Clinical Consultant. A Clinical Consultant is responsible for ensuring:

• Test reports include pertinent information for test interpretation, and
• Availability for consultation concerning test results and the interpretation of those results as they relate to specific patient conditions

May serve as Technical Supervisor. A Technical Supervisor is responsible for ensuring:

• Appropriate test method selection
• Adequate method validation to determine the accuracy and precision of the test
• Enrollment and active participation of the laboratory in a CMS-approved proficiency testing (PT) program for the test performed in accordance with the CLIA requirements and:

o   PT results are returned within established time frames. PT reports are reviewed by the appropriate staff

o   If applicable, corrective action plans are developed and executed for any unacceptable or unsatisfactory PT results.

• Quality assessment and quality control programs are established and maintained
• Acceptable analytical test performance is established and maintained for each test system
• Remedial actions are taken and documented when significant deviations from the laboratory’s established performance characteristics are identified, and patient test results are reported only when the system is functioning properly
• Personnel have been appropriately trained and demonstrate competency prior to testing patient specimens
• Policies and procedures are established for monitoring personnel competency in all phases (preanalytical, analytical, and postanalytical) of testing to ensure the ongoing competency of all individuals who perform testing;
• Remedial training or continuing education needs are identified, and training is provided; and an approved procedure manual is available to all personnel.

QUALIFICATIONS:

• MD, DO and/or PhD in genetics or related field required.
• ABMGG board-certified in Laboratory Genetics and Genomics (LGG) or Clinical Molecular Genetics, ABP board-certified in Molecular Genetic Pathology, or equivalent doctoral-level board required. Board-eligible candidates with strong operational and research experience will also be considered. 
• Current California license as a Clinical Genetic Molecular Biologist required, or applicants must be eligible for the license.
• Current Certificate of Qualification in Genetic Testing from the NYS CLEP required, or applicants must be eligible for the certificate.
• 2 or more years of experience in a CLIA-certified clinical laboratory setting analyzing, interpreting, and reporting clinical genetic/genomic data. Experience within a high-volume laboratory is preferred.
• Knowledge of CAP, CLIA, California, and New York state regulations.
• This role works with PHI on a regular basis both in paper and electronic form and has access to various technologies to access PHI (paper and electronic) in order to perform the job.
• Employees must complete training relating to HIPAA/PHI privacy, General Policies and Procedure Compliance training and security training as soon as possible but not later than the first 30 days of hire.
• Must maintain a current status on Natera training requirements.
• Employee must pass post-offer criminal background check.

KNOWLEDGE, SKILLS, AND ABILITIES:

• Excellent written and oral communication skills.
• Experience within a high-complexity laboratory environment that offers screening, constitutional, and/or somatic clinical testing. Strong background in evaluating, interpreting, and reporting of advanced, high-complexity molecular technologies used in genetic variation detection and/or cfDNA analysis.
• Understanding of statistical measures utilized in genetic testing and screening.

PHYSICAL DEMANDS & WORK ENVIRONMENT:

• Duties typically performed in BSL-2 lab settings.
• Standing or sitting for long periods of time may be necessary.
• Duties may require working various shifts and/or weekends.

Travel required for this position:

No   ☐ or Yes   ☒:  If yes state anticipated percent for travel: up to 10%

At Personalis, we are transforming the active management of cancer through breakthrough personalized testing. We aim to drive a new paradigm for cancer management, guiding care from biopsy through the life of the patient. Our highly sensitive assays combine tumor-and-normal profiling with proprietary algorithms to deliver advanced insights even as cancer evolves over time. Our products are designed to detect minimal residual disease (MRD) and recurrence at the earliest timepoints, enable selection of targeted therapies based on ultra-comprehensive genomic profiling, and enhance biomarker strategy for drug development. Personalis is based in Fremont, California.

Shift(s) Available:

• Sunday - Thursday: 10pm - 6:30am (3rd Shift)
• Tuesday - Saturday: 2pm - 10:30pm (PM Shift)

Training hours may be different from your shift schedule. The PM and 3rd shift would be eligible for an additional shift premium.

Summary:

A CLS Supervisor performs and reports on clinical laboratory testing that aids physicians in diagnosing and treating patients. A key part of the role is supervising team members and ensuring that all laboratory procedures are followed for specimen handling, next-generation sequencing (NGS) processes, test analyses, and the accurate maintenance of patient records.

In our lab, we foster a positive, friendly, and team-based environment. We all pitch in to achieve our common goals and support each other. You'll work in a dynamic atmosphere, gaining hands-on experience at multiple benches, including extractions, library preparation, and sequencing. You'll also partner with our lab assistants to coordinate pre-analytical and post-analytical tasks.

Responsibilities: 

• Perform and report clinical laboratory testing on patient samples to aid physicians diagnose and treat patients. This includes the following areas:
• Extractions
• Library Preparation
• Enrichments
• Sequencing
• Handle and process all patient specimens according to laboratory procedures, ensuring accurate and timely record-keeping and reporting of results.
• Select, implement, and evaluate quality control materials for statistical process control of laboratory assays.
• Troubleshoot assays and equipment when quality control materials fail to perform as expected.
• Document all corrective actions taken when test systems deviate from established performance specifications.
• Assist in audits by regulatory bodies like CAP and external customers.
• Participate in activities that support the laboratory's necessary licensure, including quality management and on-site inspections.
• Identify and correct problems that may negatively affect test performance or result reporting. If a problem cannot be immediately corrected, notify a supervisor, clinical consultant, or director.
• Train other CLS and lab personnel on laboratory methods.
• Monitor the activities of non-licensed staff.
• Provide guidance to team members on troubleshooting and deviation investigations.
• Assist in assay development activities.
• Demonstrate strong analytical skills and independent critical thinking.
• Apply technical and functional knowledge to help the team meet its goals.
• Work independently to identify and resolve complex, open-ended problems.

Requirements:

• Education: Bachelor's degree, preferably in sciences or related discipline.
• Licensure: Valid California Clinical Laboratory Scientist (CLS) or Clinical Genetic Molecular Biologist Scientist (CGMBS) license.
• Experience: At least four years of CLS experience in a clinical laboratory environment. Minimum 1 year experience in a Lead role is required.
• Preferred Skills: Experience with manual DNA/RNA extractions, manual library preparation, and automated liquid handlers.

The hiring range for this position is $72.10 to $81.70 per hour plus applicable shift differential. The offer will take into account internal equity and also may vary depending on the candidate’s geographic region, job-related knowledge, skills, and experience among other factors. Our full-time regular positions also include an annual performance-based bonus (or a sales incentive plan) and long-term incentive units (equity) provided as part of our compensation package, in addition to a full range of medical, financial, and/or other benefits, dependent on the level and position offered.

Personalis is an equal opportunity employer and is committed to the full inclusion of all individuals. As part of this commitment, Personalis will ensure that persons with disabilities are provided with reasonable accommodations. If you need an accommodation to participate in the job application or interview process, to perform essential job functions, and/or to receive other benefits and privileges of employment, please let your recruiter know, if/when they contact you.

Protecting Our Candidates: At Personalis, we value your security. Please note that all official correspondence from our team will come exclusively from @personalis.com email addresses. We will never ask for personal financial information or conduct interviews over text or chat platforms. If you receive a suspicious request, it is likely a scam. We are committed to a safe recruitment experience and actively work with authorities to investigate and prosecute cyber crimes targeting our community.

Personalis offers a competitive compensation package and benefits including medical, dental, vision, 401(k) match, ESPP, tuition reimbursement, sick/vacation time, commuter benefits/ EV charging stations, onsite gym, and wellness benefits. (For US only, benefits in other countries may vary.)

#LI-KK1 #LI-Onsite

About NewLimit

NewLimit is a biotechnology company working to radically extend human healthspan. We’re developing medicines to treat age-related diseases by reprogramming the epigenome, a new therapeutic mechanism to restore regenerative potential in aged and diseased cells. We leverage functional genomics, pooled perturbation screening, and machine learning models to unravel the biology of epigenetic aging and disease using experiments of unprecedented scale.

Description

NewLimit is seeking a Computational Biologist to join our Predict team. In this role, you will develop, improve, and operate bioinformatics pipelines supporting large-scale single-cell perturbation screens. Success in this position requires a deep attention to methodological detail at every stage of the analysis, as well as careful measurement and evaluation of pipeline performance.

You will work closely with experimentalists and computational scientists to maintain core infrastructure, assess emerging analysis tools, and build robust software solutions that improve efficiency, scalability, and reliability.

As a member of our team, you will:

• Collaborate with Write, Read, and Predict teams to support the design, execution, and interpretation of experiments using single-cell and multi-omics data
• Contribute to the development and implementation of primary and secondary analysis software.
• Improve and run production pipelines for large-scale single-cell perturbation screens to ensure timely and reliable data delivery
• Contribute to the development of reproducible, well-documented computational workflows and internal best practices
• Develop microservice web applications and integrations that reduce wet lab manual effort and improve data flow between teams

Requirements

• Bachelor’s, Master's, or PhD in Bioinformatics, Biostatistics, Computational Biology, Computer Science, or a related technical field
• Experience analyzing and interpreting single-cell or multi-omics datasets (e.g., scRNA-seq, multiome, scATAC-seq), with hands-on exposure to perturbation screens preferred
• Familiarity with core single-cell bioinformatics workflows, including demultiplexing, alignment, and quality control
• Strong software engineering fundamentals and experience working with bioinformatics tools and pipelines
• Working knowledge of statistical and machine learning methods applied to biological data (e.g. regression analysis, supervised learning) sufficient to critically evaluate analytical choices and interpret results conceptually

Nice to haves

• Proficiency with Python-based data science tools (NumPy, SciPy, Pandas)
• Experience with cloud computing environments (AWS, GCP, or Azure)
• Strong Python programming skills and comfort working in Unix-based environments
• Experience with containerized workflows (Docker, Singularity)
• Familiarity with molecular biology workflows and experimental genomics

Benefits

• Health, dental, and vision insurance
• 401(k) with company match
• Industry-leading paid time off (PTO) -- 20 days/year for all employees + holidays
• Paid parental leave
• Meals and snacks on-site

Salary Range: $130,000 to $170,000. Compensation for the role will depend on a number of factors, including a candidate’s qualifications, skills, competencies, and experience. NewLimit offers a competitive benefits package, which includes a 401k, healthcare coverage, and 20 days of PTO. Learn more at: https://www.newlimit.com/careers   *This compensation and benefits information is based on Company's good faith estimate as of the date of publication and may be modified in the future.

About the Role

We are seeking an exceptional Staff Computational Biologist to drive the next generation of software and data products supporting Target Identification and Prioritization across our research organization. This hybrid role is ideal for someone who thrives at the intersection of biology, computation, product strategy, and engineering execution.

As a senior member of the Translational Platform Engineering team, you will act as a product owner, technical strategist, and rapid prototyper, responsible for shaping the roadmap and delivering tools that power discovery teams. Your day to day includes working with biology data scientists to harden their notebooks and workflows, pushing new releases to production (on a predictable schedule), and sitting with biologists and chemists as they use the UIs to advance our translational biology efforts. The Staff Computational Biologist is the key to translating use cases into technical specifications for engineering teams.

This is a highly visible and impactful role where you will contribute to a human-biology-first approach to drug discovery programs by leading the end-to-end lifecycle of platform capabilities used daily by our Target ID scientists.

What You’ll Do…

• Own the product roadmap for Target ID software.
• Gather and prioritize scientific requirements from internal users.
• Translate use cases into technical specifications for engineering teams.
• Rapidly prototype computational solutions using Python.
• Develop and maintain internal packages, reproducible workflows, and APIs.
• Establish documentation, onboarding materials, and best practices for internal platform usage.
• Lead cross-functional project execution (data engineering, software engineering).
• Follow good engineering practices (i.e. CI/CD, predictable demo cadence, etc.)

What You Bring...

• Bachelor's/ Master's degree in relevant field (computational biology, bioinformatics, systems biology, computer science) or equivalent relevant education and experience
• 6+ years industry experience in computational biology or data-driven discovery; minimum 1 years’ experience in software engineering and data engineering teams
• Proficiency working with programming languages Python, and R, modern development frameworks and developing internal packages
• Experience with omics/translational data analysis, scalable ETL pipelines, data modeling, and associated QC
• 1+ years’ experience leading complex projects as product owner
• Experience supporting target identification, prioritization, or multi-modal analysis.

Nice to have...

• Experience with dashboard development (e.g. Shiny, Dash, Streamlit, React, Veu.js).
• Understanding of cloud-native tools and modern data platforms (AWS/GCP/Azure).
• Familiarity with the drug discovery and development process is a plus

ESA is seeking variable part-time (on-call) field biologists with 5+ years' experience. Qualified candidates must be located in the San Francisco Bay Area, vicinity of Sacramento, Sacramento-San Joaquin River Delta, Central Valley, or within 3 hours.  All qualified candidates must be willing & able to travel as needed. Preference given to candidates located in the bay area and central valley of CA.  The need for on-call services is expected to be greatest in late summer through fall with periodic work throughout other parts of the year. Additional work beyond this period may be requested. 

Who You Are 

• Qualified candidates should have previous experience performing natural resource-related evaluations, technical studies, analyses and tasks requiring knowledge based on education and at least two years of professional experience. 
• Previous construction monitoring experience required.
• Qualified candidates must demonstrate the ability to perform all aspects of biological monitoring on small to large, complex construction projects. Some night and/or weekend work may be assigned. General experience with wildlife and vegetation species from the geographic area of work: California Central Valley and San Francisco Bay Area.
• Qualified candidates must have experience surveying and monitoring CA nesting birds. 
• Preference given to candidates with direct experience surveying, handling, and monitoring for, or with monitoring approvals by state and federal agencies for one or more of the following species: San Joaquin kit fox, California tiger salamander, California red-legged frog, northwestern pond turtle, San Francisco garter snake, giant garter snake, California black rail, western burrowing owl, western spadefoot, vernal pool brachiopods, Swainson’s hawk and/or other nesting birds, Crotch’s bumble bee, and bats.
• You enjoy fieldwork and can walk long distances carrying a backpack; and are able to lift at least 50 pounds. You are confident working outside, in remote and rural settings, as well as in urban environments. Physical outdoor work may include, but may not be limited to, work in all types of weather, traversing uneven ground and sometimes steep terrain in vegetated environments, agricultural fields, arid lands, and along stream banks. You may be exposed to inclement weather and uncomfortable working conditions. Some early morning, late night and/or weekend work, as well as long hours may be required

What You Will Do for ESA

Preference will be given to candidates with direct experience surveying, handling, and monitoring for, or with monitoring approvals by state and federal agencies for one or more of the following species: San Joaquin kit fox, California tiger salamander, California red-legged frog, northwestern pond turtle, San Francisco garter snake, giant garter snake, California black rail, western burrowing owl, western spadefoot, vernal pool brachiopods, Swainson’s hawk and/or other nesting birds, Crotch’s bumble bee, and bats. Successful candidates will fulfill the following duties:

• Perform biological compliance monitoring and reporting at active construction sites to ensure conformance with environmental/permit requirements
• Conduct special-status species surveys and nesting bird surveys
• Identify and may relocate sensitive species, when needed and if agency-approved
• Effectively communicate with senior ESA staff, construction crews, project personnel, and project management staff
• Take initiative and contribute to a respectful, feedback-driven team culture
• Maintain daily written monitoring and inspection logs, including utilizing electronic data collection tools, such as Fulcrum and Trello
• Enter data into an on-line GIS mapping application, such as Fieldmaps, Collector, Survey 123
• Deliver worker environmental awareness training to on-site staff
• Must possess a valid driver’s license and have own transportation to project sites
• Must have a smart phone with sufficient data plan to collect necessary data on-site
• Comply with all safety requirements and policies
• Able to lift up to 40 pounds
• Confident in working outside, potentially in remote or rural settings, as well as in urban environments.
• Other ad hoc tasks as needed

What’s Special About Our Biology Team

Our Biology Team includes biologists, restoration ecologists, permitting specialists, conservation biologists, and environmental scientists that provide expertise for many municipalities throughout California. Our work matters because it helps communities shape a positive future for their citizens in balance with conserving our state’s sensitive natural resources. We value creative thinking, teamwork, and multi-disciplinary and cross-disciplinary engagement and integration. 

We encourage you to read about some of the exciting projects we have recently completed. 

What’s Special About ESA

Joining ESA means becoming part of a close-knit team of environmental professionals who contribute to outstanding projects, improve environmental stewardship, and advance a more sustainable and resilient future for our communities and wild places.

You are eligible to participate in ESA’s sick leave program. You may be eligible to participate in our employee stock ownership program and tax deferred 401(k) plan if you meet the eligibility requirements for these plans.

ESA is seeking variable part-time (on-call) field biologists with 0-5 years experience.  Preference given to candidates with 1+ years of professional experience. Qualified candidates must be located in the San Francisco Bay Area, vicinity of Sacramento, Sacramento-San Joaquin River Delta, Central Valley, or within 3 hours.  All qualified candidates must be willing & able to travel as needed. Preference given to candidates located in the bay area and central valley of CA.  The need for on-call services is expected to be greatest in late summer through fall with periodic work throughout other parts of the year. Additional work beyond this period may be requested. 

Who You Are 

• Qualified candidates should have previous experience performing natural resource-related evaluations, technical studies, analyses and tasks requiring knowledge based on education and at least two years of professional experience. 
• Previous construction monitoring experience required.
• Qualified candidates must demonstrate the ability to perform all aspects of biological monitoring on small to large, complex construction projects. Some night and/or weekend work may be assigned. General experience with wildlife and vegetation species from the geographic area of work: California Central Valley and San Francisco Bay Area.
• Qualified candidates must have experience surveying and monitoring CA nesting birds. 
• Preference given to candidates with direct experience surveying, handling, and monitoring for, or with monitoring approvals by state and federal agencies for one or more of the following species: San Joaquin kit fox, California tiger salamander, California red-legged frog, northwestern pond turtle, San Francisco garter snake, giant garter snake, California black rail, western burrowing owl, western spadefoot, vernal pool brachiopods, Swainson’s hawk and/or other nesting birds, Crotch’s bumble bee, and bats.
• You enjoy fieldwork and can walk long distances carrying a backpack; and are able to lift at least 50 pounds. You are confident working outside, in remote and rural settings, as well as in urban environments. Physical outdoor work may include, but may not be limited to, work in all types of weather, traversing uneven ground and sometimes steep terrain in vegetated environments, agricultural fields, arid lands, and along stream banks. You may be exposed to inclement weather and uncomfortable working conditions. Some early morning, late night and/or weekend work, as well as long hours may be required

What You Will Do for ESA

• Perform biological compliance monitoring and reporting at active construction sites to ensure conformance with environmental/permit requirements
• Conduct special-status species surveys and nesting bird surveys
• Identify and may relocate sensitive species, when needed and if agency-approved
• Effectively communicate with senior ESA staff, construction crews, project personnel, and project management staff
• Take initiative and contribute to a respectful, feedback-driven team culture
• Maintain daily written monitoring and inspection logs, including utilizing electronic data collection tools, such as Fulcrum and Trello
• Enter data into an on-line GIS mapping application, such as Fieldmaps, Collector, Survey 123
• Deliver worker environmental awareness training to on-site staff
• Must possess a valid driver’s license and have own transportation to project sites
• Must have a smart phone with sufficient data plan to collect necessary data on-site
• Comply with all safety requirements and policies
• Able to lift up to 40 pounds
• Confident in working outside, potentially in remote or rural settings, as well as in urban environments.
• Other ad hoc tasks as needed

What’s Special About Our Biology Team

Our Biology Team includes biologists, restoration ecologists, permitting specialists, conservation biologists, and environmental scientists that provide expertise for many municipalities throughout California. Our work matters because it helps communities shape a positive future for their citizens in balance with conserving our state’s sensitive natural resources. We value creative thinking, teamwork, and multi-disciplinary and cross-disciplinary engagement and integration. 

We encourage you to read about some of the exciting projects we have recently completed. 

What’s Special About ESA

Joining ESA means becoming part of a close-knit team of environmental professionals who contribute to outstanding projects, improve environmental stewardship, and advance a more sustainable and resilient future for our communities and wild places.

You are eligible to participate in ESA’s sick leave program. You may be eligible to participate in our employee stock ownership program and tax deferred 401(k) plan if you meet the eligibility requirements for these plans.

Join Our Thriving Talent Community!

Are you passionate about protecting our planet and advancing environmental science? Whether you're a biologist, planner, scientist, or environmental professional, we invite you to join our vibrant Talent Community!

Why Join Us?

• Networking Opportunities: Connect with industry leaders and peers to share insights, collaborate on projects, and expand your professional network.
• Career Growth: Access exclusive job opportunities, career development resources, and mentorship programs designed to help you advance in your career.
• Innovative Projects: Be part of groundbreaking projects that push the boundaries of sustainability, conservation, and environmental technology.
• Continuous Learning: Stay ahead of the curve with access to the latest industry trends, webinars, workshops, and certifications.
• Culture: ESA culture is built on inclusion, creativity, collaboration, and a commitment to our work, our clients, and our communities.

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tl;dr

General Proximity is a seed-stage startup developing the next generation of induced proximity medicines (IPMs). Our OmniTAC drug discovery engine furnishes molecules that co-opt existing cellular machinery to overcome therapeutic challenges, which have remained unapproachable to other modalities for decades.

We are seeking a first-rate cancer biologist to help us pioneer this uncharted frontier of drug discovery.

Our Story

A long-standing challenge in drug discovery is the development of molecules capable of modulating difficult or "undruggable" targets. Disease-causing proteins can be dysfunctional in many different ways, but our armamentarium for fixing them is quite limited. The most common mechanism of action for FDA-approved drugs is inhibition[1], but there are many other possible perturbation types whose potential remains unrealized.

General Proximity is a seed-stage drug discovery company developing a novel platform technology to solve this problem. We make bifunctional drugs that induce the modification of drug targets by existing cellular machinery (rather than through direct modulation by the drug, the classical approach).

Historically, the development of technologies that allow one to push new buttons in biology has been an incredibly fertile field for the discovery of new medicines[2, 3, 4], and our technology holds the same promise.

The Position

We are seeking an experienced cancer biologist to help lead our Biology Team. In this position, you will help lead and manage our Biology Team and work closely with our Platform Team in the development of our core drug discovery technology.  

Your responsibilities will include phenotypic assay development, establishing pre-clinical in vitro/in vivo studies, performing mechanistic studies on lead drug molecules, spearheading forays into new oncology indications, and grant writing. 

About You

High Agency. Initiative, independence, and self-accountability are some of our most valued traits.

Enthusiastic. We love people who are excited about what they are doing and are generally attempting to build a high-energy team.

Intensity and Grit. Early-stage startups are hard. Drug discovery is doubly so. We are looking for candidates who have a demonstrated ability to stick with complex problems for the long haul, with a team that has your back along the way.

Prosocial. We are here to create life-saving medicines for the patients who need it most. You should be, too.

Qualifications & Nice-To-Haves

• PhD in Cancer Biology, Cell Biology, or related field.  
• 5-7+ years of industry experience.
• Deep understanding of small-molecule drug discovery and its relationship to human disease.
• Exceptional leadership, interpersonal, and communication skills, with a track record of managing high-performing, multidisciplinary teams.
  
  
• Strong experience with:
  
  • Cellular and molecular biology, including cancer cell line work and associated assays, stable cell line generation (lentiviral and CRISPR-based systems), co-IP/pull-down assays, RNA-seq, global proteomics, flow cytometry, plasmid design/cloning etc.
  • Pre-clinical characterization and mechanistic elucidation of small-molecule drug candidates
  • Mechanistic studies of cancer cell signaling and PTM analysis
  • Phenotypic assay development for cancer drug discovery (low to high throughput)
  • Small molecule drug development campaigns (hit discovery, hit validation, dose-response studies, SAR and MOA studies)

• Proficiency in:  
  • Managing a team of exceptional scientists and research associates 
  • Target/indication selection
  • Animal models of cancer (GEMM, orthotopic, xenograft models), in vivo study design, and PK/PD interpretation
  • Managing CROs for in vitro and in vivo studies
  • Grant writing 

• Nice to have:
  • Experience navigating IND-enabling studies and working on teams that have successfully advanced research to the clinic
  • Experience working at the interface of cancer biology and chemistry  
  • Familiarity or experience with PROTAC/next-gen IPM technologies
  • Experience with PPI techniques (e.g., BRET, APEX/BioID, AlphaScreen etc.)

Benefits

• Strong equity incentives. We are looking for candidates who will bring a strong sense of ownership to drive their project areas forward, and we believe that you deserve to be compensated accordingly.
• Top tier medical, dental, and vision coverage + One Medical membership.
• 401(k) retirement plans.
• Education and health/fitness incentive programs.
• Meditation retreats—do a ten-day Vipassana retreat without counting towards vacation days. 
• Reading budget! We will buy you books. 📚
• Located in the MBC BioLabs at 135 Mississippi Street, an entrepreneurial hub full of the best scientists and operators the Bay Area has to offer. Our lab is a very short walk from the 22nd St Caltrain Station and a number of wonderful restaurants and cafés.

About Us

Work Hard/Play Hard. We believe time is our most valuable commodity, so we strive to create a culture that reflects this. We won’t drag you through unnecessary meetings or email you at 7 PM on a Saturday. When we're at work, we're there to get things done, and when we're off, we're really off. 🌴

Strong Communication. We like well-written documents over PowerPoints, OKRs over vague mission statements, and weekly one-on-ones over yearly reviews.

Writing First. We have a "writing-first" culture. We believe that clarity of writing reflects clarity of thinking and that the benefits of well-written documentation in a scientific environment are innumerable: democratization of ideation and decision-making, increased reproducibility, quicker scaling and onboarding, and better company-wide alignment, to name a few.

Growth. As an early-stage startup, we value scientists with an independent, can-do attitude. The more hats you can wear, the better. Our job as employers is to put you in positive feedback loops so you can grow in the direction of your choosing.

Title and compensation commensurate with experience. Applications from candidates of diverse backgrounds, women, and members of underrepresented minority groups are particularly welcomed. We look forward to hearing from you. :)

More info at jobs.generalproximity.bio

Position Summary

We are seeking a Computational Biologist who is passionate about using data-driven, scalable methods to reveal biological insights. The ideal candidate is an independent thinker with strong computational and quantitative skills, and the ability to collaborate closely with both experimental and computational scientists. You will design, implement, and scale computational pipelines for single-cell perturbation datasets, while contributing to model development and experimental design.

This is a unique opportunity to join a dynamic, interdisciplinary environment and help shape Neptune Bio’s computational strategy and infrastructure.

Key Responsibilities

• Develop, innovate, and maintain advanced computational methods to process, analyze, and interpret large-scale single-cell genomics and perturbation datasets.
• Collaborate with wet-lab and computational teams to integrate data from diverse experimental modalities and guide experimental design.
• Build, optimize, and scale data analysis pipelines using modern cloud computing environments (e.g., AWS, GCP, Azure).
• Contribute to Neptune Bio’s data infrastructure, ensuring reproducibility, scalability, and efficient access to large datasets.
• Stay current with advances in computational biology, machine learning, and scalable infrastructure, applying them to ongoing research challenges.
• Communicate findings clearly through reports, visualizations, and presentations to multidisciplinary audiences.

Qualification and Education Requirements

You must have:

• Ph.D. in Bioinformatics, Computational Biology, Computer Science, or a related quantitative field, OR equivalent experience (e.g., BS/MS with ≥3 years of relevant experience).
• Proficiency in Python, R, and Unix/Linux environments
• Demonstrated experience in single-cell or multi-omics data analysis.
• Solid understanding of statistics, data modeling, and modern machine learning approaches.
• Experience deploying and scaling computational pipelines on cloud platforms (AWS, GCP, or similar).
• Strong communication skills and enthusiasm for working in a collaborative, fast-paced environment.

Additional preferred experience includes:

• Background in functional genomics, CRISPR screens, or perturb-seq analysis.
• Experience integrating multi-source data to derive novel and impactful insights.
• Expertise in data engineering and reproducible research tools (e.g., Docker, Nextflow, Snakemake) as well as familiarity with cloud-native architectures and distributed compute.
• Strong publication record demonstrating innovation in computational methods or biological data analysis.
• Experience with deep learning frameworks such as PyTorch or TensorFlow.