The Opportunity:

The One Medical Virtual Medical Team (VMT) is a leading provider of virtual clinical care, providing world-class, convenient, evidence-based virtual medical care to One Medical patients in concert with their primary care providers. Through advanced technology and a team-based approach, we care for patients 24 hours a day, 365 days a year. Our team is united by intellectual curiosity, inclusiveness, and a powerful mission: transforming healthcare and bringing world-class primary care to everyone.

Employment type:

• Full time 40 hours including evenings and weekends

What you’ll be working on:

• Treating patients via tele-health visits, including telephonic triage calls, video visit appointments, and email follow-ups
• Continuous learning during weekly Clinical Rounds and through other modalities
• Ongoing collaboration with both virtual and in-office teammates via daily huddles
• Utilization of your specific clinical training and opportunities to give exceptional care to patients virtually
• Willing to obtain additional state licensure and credentialing for One Medical virtual primary care in additional states

Education, licenses, and experiences required for this role:

• Completion of master’s degree in an accredited Physician Assistant program (MSPAS)  and is maintaining active NCCPA certification
• In the past 5 years, practiced as an Advanced Practitioner for at least:
• 2 years in an outpatient primary care setting seeing patients of all ages (0+), OR 2 years in an urgent care or emergency medicine setting seeing patients of all ages (0+) 
• Currently licensed in CA or AZ with ability to obtain additional state licenses
• Ability to work weekday and weekend shifts (every other Saturday AND or Sunday required)
• Current shifts range from (6am - 12am PST)
• Excellent clinical and communication skills 

One Medical providers also demonstrate:

• A passion for human-centered primary care 
• The ability to successfully communicate with and provide care to individuals of all backgrounds   
• The ability to effectively use technology to deliver high quality care
• Clinical proficiency in evidence-based primary care
• The desire to be an integral part of a team dedicated to changing healthcare delivery
• An openness to feedback and reflection to gain productive insight into strengths and weaknesses
• The ability to confidently navigate uncertain situations with both patients and colleagues
• Readiness to adapt personal and interpersonal behavior to meet the needs of our patients

This is a full-time virtual role. 

One Medical is committed to fair and equitable compensation practices.

The base hourly range for this role is $59.10 to $65.50 per hour (plus evening and weekend differential) based on a full-time schedule. Final determination of starting pay may vary based on factors such as practice experience and patient care schedule. Additional pay may be determined for those candidates that exceed these specified qualifications and requirements. For more information, visit https://www.onemedical.com/careers/.

Position Summary

We are currently seeking a dedicated and experienced Registered Nurse to support the clinical operations at our La Jolla Clinic. This role is ideal for someone who thrives in a dynamic, patient-centered environment and is passionate about delivering high-quality care while supporting a collaborative clinical team. We are particularly interested in RNs with backgrounds in ICU, hospital, or other acute care settings, as these experiences bring valuable clinical insight and readiness to lead in a fast-paced outpatient environment. 

This is a full-time, non-exempt (hourly) position, scheduled for 40 hours per week. Work hours may vary based on assigned clinic location, Monday through Friday. This role will be based primarily in our La Jolla clinic but may also provide support to other nearby locations. The ideal candidate is adaptable and enjoys collaborating across multiple sites to ensure seamless operations and excellent patient experiences.

Key Responsibilities

• Clinical Procedures & Diagnostic Testing:
  
  • Perform a variety of allergy and asthma testing procedures, including: 
  • Allergy skin testing 
  • Spirometry, DLCO, and fractional exhaled nitric oxide (FeNO) 
  • Mannitol challenges 
  • Drug challenges 
  • Food challenges 
  • Emergency Response & Treatment Administration 
  • Assist in the treatment of anaphylaxis, including: 
    • Administration of injectable epinephrine 
    • IV fluids (ensuring this skillset is proficient)  
    • Oxygen and nebulized medications 
    • Administer intravenous medications and infusions, (In accordance with the California Board of Registered Nursing scope-of-practice guidelines) including: 
    • IVIG 
    • Monoclonal antibody therapies 
• Clinical Oversight & SOP Implementation:
  
  • Oversee the implementation of standard operating procedures (SOPs) across all areas of clinical care, including: 
  • Allergy immunotherapy (injections) 
  • Skin testing protocols 
  • Food and drug challenge protocols 
  • Oral immunotherapy (OIT) treatments 
  • Maintain and manage staff training logs and ensure protocol compliance 
• Clinical Research Coordination:
  
  • Participate in and oversee the conduct of clinical trials: 
  • Supervise administration of investigational products by study coordinators 
  • Support and train clinical research staff; address medical questions 
  • Ensure accurate completion of study documentation, including: 
  • Training logs 
  • Delegation of authority forms 
  • Equipment calibration and maintenance logs 
• Oral Immunotherapy (OIT) Program Management:
  • Oversee the preparation of food allergen solutions 
  • Participate in and supervise: 
  • Food up dosing appointments 
  • In-office food challenges 
• Additional duties as assigned.  

Qualifications & Requirements

• Licensure & Certifications:
  • Licensed RN in the state of California. 
  • Current CPR certification (or willingness to obtain). 
  • Current BLS (Basic Life Support) certification. 
• Experience: 
  • Nursing for 1 year (preferred) 
  • Allergy/immunology experience preferred. 
  • Experience with EMR systems; ModMed experience a plus. 
• Skills & Abilities:
  • Comfortable performing complex tasks and applying independent knowledge and judgment. 
  • Skilled in pulmonary function testing, FeNO testing, and peak flow monitoring. 
  • Phlebotomy experience. 
  • Strong patient education skills regarding medications and environmental controls. 
  • Exceptional attention to detail and organizational skills. 
  • Strong verbal and written communication skills. 
  • Ability to multitask, prioritize duties, and work independently in a dynamic clinical environment. 
  • Professional, compassionate demeanor and a commitment to high-quality patient care. 
  • Handling IV fluids administration and related tasks, including preparation, setup, monitoring of infusion, and documentation, while ensuring strict adherence to clinical protocols and safety standards. Candidate must demonstrate proficiency and confidence in this skillset 
  • Strong organizational and communication skills required; able to work in a team environment 
• Physical Requirements:
  • Ability to stand and walk for extended periods (up to 8-hour shifts). 
  • Occasional lifting of objects weighing 5–25 pounds (up to 4 feet in distance). 
  • Occasional bending, stooping, and reaching for clinical tasks.
  • Frequent use of hands and fingers for patient care, typing, and equipment handling.
  •  Normal (or corrected) vision and hearing required. 
  • Ability to move quickly and efficiently in a fast-paced clinical setting. 
  • Ability to move throughout exam rooms, front office, and supply areas.

Compensation

The hourly range for this position is $38.00 - $55.000/hour. The actual compensation for this role will be determined by a variety of factors, including but not limited to the candidate’s skills, education, and experience.

ESSENTIAL JOB FUNCTIONS:

• Manage Senior Accountant and ensure timely, accurate processing of journal entries, reconciliations and various account analyses for R&D functions such as translational research, development, diagnostics, pharmacology, and regulatory affairs, and adherence to company policies.
• Review and approve invoices for payment. Ensure proper coding, two-way match, and approval workflows.
• Perform and review journal entries and balance sheet reconciliations for key accounts such as accrued R&D contracts, prepaid R&D ST, and prepaid R&D LT.
• Review various related parties and partner transactions including reconciliations, and analysis.
• Perform and review monthly and quarterly variance analyses for operating expenses, R&D functions, projects, and key accounts; investigate and resolve discrepancies proactively.
• Ensure compliance with U.S. GAAP, SOX requirements, and internal accounting policies across all responsible functions and processes.
• Support the design, implementation, and ongoing maintenance of Sarbanes‑Oxley internal controls, including documentation and testing.
• Assist with external financial audits by preparing schedules and responding to auditor requests and inquiries.
• Review monthly purchase order coding, partner with project managers and accounting staff to ensure proper coding for all new purchase orders.
• Apply strong analytical skills and critical thinking to identify issues, recommend improvements, and enhance the accuracy, efficiency, and quality of accounting processes.
• Perform additional duties and ad hoc projects as needed to support Finance leadership and departmental goals

Job Specifications:

• Bachelor’s degree in accounting, or other related discipline, or the equivalent knowledge and experience required.
• Experience in the biotech/pharmaceutical industry required
• A minimum of 6-8 years’ relevant accounting experience, preferably in a combination of the following monthly close process, bank reconciliations, balance sheet reconciliations, contract accruals
• Excellent communication and people skills and the ability to interface with various levels of co-workers, upper management, and external customers while maintaining a high degree of confidentiality.
• Experience working in publicly traded company and life science industry preferred.
• Knowledge of US GAAP and internal control principles for a public corporation.
• ERP experience required; experience with NetSuite, Blackline, Coupa and Concur preferred.
• Skilled in the use of Microsoft Office Suite with intermediate to advanced Excel skills.
• Detail oriented with good analytical skills.
• Exercises independent judgment in managing operational decisions within their area; proactively identifies issues and determines when to escalate more complex or cross-functional decisions.
• Serves as a key point of contact for cross-functional partners withing their area, ensuring alignment and proactively addressing coordination needs to support team deliverables.
• Strong time management skills and ability to independently organize multiple tasks of varying priorities and meet critical deadlines in a fast-paced environment.
• Ability to work in team environment and willing to assist other team members to achieve team goals and objectives.

The base range for this role at a Senior Manager level is $143,000 - $176,500. Individual pay may vary based on additional factors, including, and without limitation, job-related skills, experience, work location, and relevant education or training. Kura's compensation package also includes generous benefits, equity, and participation in an annual target bonus.

#LI-RM1

Your next role as a Miracle Maker 

Maravai LifeSciences is seeking a #MiracleMaker to join our manufacturing team as a Temporary Manufacturing Associate I, Oligo. As a Temporary Manufacturing Associate I, Oligo, you will support daily production operations by performing basic production tasks, preparing equipment and materials, executing routine workflows, and maintaining proper documentation. Works under close supervision within ISO-classified manufacturing spaces to produce research and clinical-grade components. Learns and applies operational procedures while developing foundational skills in oligo production technologies.

How you will make an impact: 

• Reviews daily production tasks and follows established procedures for material preparation, equipment set-up, and execution of routine processes.
• Assists in preparing production areas for cGMP project initiation or changeover.
• Documents production activities by accurately completing forms, logs, and batch-related records in compliance with GDP.
• Operates and cleans equipment following established instructions and escalates equipment issues or deviations.
• Supports execution of batch records and follows SOPs; may assist in SOP revisions under guidance.
• Participates in training and completes required cGMP and company training within defined timelines.
• Maintains a clean and safe work environment by following SOPs and housekeeping expectations.
• Communicates progress, issues, and observations to supervisors or senior associates.
• Collaborates with Manufacturing Associate II staff and other support groups to ensure workflow alignment.
• Performs basic oligo synthesis, purification, processing steps, and associated documentation with supervision.
• Performs other functions and duties as required

 The skills and experience that you will bring: 

• Bachelor's Degree in life science field or related field preferably in Chemistry/Biochemistry/Biology/Molecular Biology or equivalent experience
• 1+ years of experience in a Biochemistry manufacturing laboratory preferred
• Exposure in a cGMP/ ISO 7/ ISO 8 clean room environment desired
• Experience with executing SOPs
• Proficiency in Microsoft Office Suite desired
• Display strong organizational skills, detail-oriented, and demonstrated problem-solving abilities
• Excellent written and verbal communication skills
• Self-motivated and able to organize and prioritize multiple tasks

The anticipated salary range for this position is $20.00 - $25.00. The salary offer will depend on multiple factors which may include the successful candidate's skills, experience and other qualifications, as well as the location of the role. 

#LI-Onsite

Seeking talent near: Princeton, NJ ; San Diego, CA

Position Summary

The Senior Manager R&D Learning & Development supports the development, implementation, and ongoing management of onboarding, training strategies, systems training, and learning processes that build scientific, operational, and future‑ready capabilities across the Research and Development organization and pipeline.

Primary Responsibilities

• Assist in the design, implementation, and continuous improvement of a tiered onboarding and capability-building curriculum aligned to the evolving needs of the R&D pipeline, including discovery, early development, and late-stage programs.

• Utilize experiential learning best practices to effectively engage adult learners and ensure the successful transfer of knowledge.

• Support the management of GxP, congress, and data training with internal stakeholders.

• Collaborate cross-functionally with R&D subject matter experts to develop disease area, modality, platform, and pipeline-focused training, including investigational asset education and emerging science.

• Lead and support training initiatives with internal stakeholders.

• Facilitate the management and development of learning modules in partnership with external vendors.

• Oversee the development of advanced, recurrent, and future-focused training programs, including non-technical skills critical to R&D success (e.g., scientific storytelling, data interpretation, matrix leadership, and decision-making).

• Ensure all content and training are in compliance with internal policies and external regulations.

• Lead cross-functional collaboration to enable systems and digital capability development that support scalable, data-driven learning across the R&D organization.

• Other responsibilities as assigned.

Education/Experience/Skills

Masters’ degree in Life Sciences or a related field; Advanced science degree strongly preferred (PharmD, PhD, MD).  Targeting 7 years of progressively responsible experience in psychiatry, neurology, or rare disease preferably in a pharmaceutical or biotech environment.  Psychiatry, neurology, or rare disease experience strongly desired. Must have education or training experience, including design, delivery, and evaluation of learning programs.  An equivalent combination of relevant education and experience may be considered.

Key Skills:

• Knowledge of scientific, clinical and/or therapeutic area is preferred.

• Skilled and knowledgeable presenter, able to communicate complex scientific information clearly and effectively.

• Excellent oral and writing skills.

• Proficient computer skills in Microsoft Word, Excel and Outlook.

• Experience working with external vendors.

• Highly detail oriented, self-disciplined, and ability to work independently with limited direction to resolve discrepancies and issues.

• Ability to take initiative and demonstrate follow through skills.

• Excellent planning and organizational skills.

• Effective interpersonal skills to collaborate effectively in a matrix organizational structure, and with all levels within the organization.

• Ability to manage multiple priorities and work cross-functionally in a fast-paced environment.

• Must be willing and able to travel both domestically and internationally.

Physical Requirements

This role involves regular standing, walking, sitting, and the use of hands for handling or operating equipment. The employee may also need to reach, climb, balance, stoop, kneel, crouch, and maintain visual, verbal, and auditory communication in a standard office environment and while working independently from remote locations. The employee must occasionally lift and/or move up to 20 pounds.  This position requires the ability to travel independently overnight and/or work after hours as required by travel schedules or business needs.

#LI-HYBRID #NC1

Position Summary

The Sr. Director will support R&D teams through the management of reporting and analytics, workforce and budget planning and oversight, and driving strategic and transformational projects.  S/he will assist with the creation and implementation of policies and procedures.  This role will serve as a key resource across all therapeutic areas and research phases and will be required to work closely with R&D teams and vendors. 

Primary Responsibilities

Reporting and Analytics

• Oversee and manage the Acadia Clinical Command Center, including implementation, oversight, continuous improvement, and change management.
• Develop mechanisms and reports to drive data quality.
• Support data governance activities in support of the Clinical Command Center.
• Primary interface with vendor counterparts around data and to support reporting.
• Partner with cross-functional teams and external vendors to integrate data sources into the Clinical Data Warehouse.
• Oversee and drive high levels of data quality across R&D.
• Implement operational KPIs and establish governance with the purpose of driving improvements in operational efficiency.
• Develop dashboards and reports appropriate to multiple layers of functional leadership to support analysis and drive decisions.
• Point of contact for ad hoc analyses to support business questions.

Workforce Planning and Management

• Develop resource demand algorithms for R&D functions and roles.
• Establish and maintain workforce data for both internal and external staff (e.g. headcount, Functional Service Providers, contractors).
• Lead resource algorithm governance committee.
• Lead R&D workforce management through the regular review of resources, risks, issues and opportunities with key stakeholders.
• Generate and maintain access to workforce forecast data.
• Drive, in partnership with P&P, reporting around R&D headcount resources.
• Support strategic planning and portfolio decision-making through workforce modeling.

Leadership and Change Management

• Lead transformational projects across the R&D organization, as assigned.
• Lead process changes, stakeholder readiness and communication strategy as required.
• Support Business Development integration activities, as needed.
• Other responsibilities as assigned.

Education/Experience/Skills

Bachelor’s degree in a life science or a related field.  Targeting 12 years of progressively responsible experience in R&D Operations, preferably in a pharmaceutical or biotech environment.  An equivalent combination of relevant education and experience may be considered.

Key Skills:

• Advanced skills in data transformation and visualization techniques and tools (e.g. Excel, PowerBI, Tableau, Alteryx).
• Advanced skills in managing a broad-scope of multiple priorities & projects and work cross-functionally in a fast-paced environment..
• Excellent communication skills (both written and verbal), including experience in preparing/presenting key information to senior leadership.
• Ability to think and plan strategically.
• Strong analytical skills with the ability to understand scientific and financial data, recognize key issues and establish priorities.
• Committed to continuous improvement and consistently delivering measurable results
• Naturally connects and builds strong relationships with others, demonstrating strong emotional intelligence and an ability to communicate clearly and persuasively
• High degree of customer focus.
• Mentor and develop team members, fostering a culture of continuous improvement.
• Requires problem-solving abilities at both strategic and operational levels.
• Must be willing and able to travel both domestically and internationally.

Physical Requirements

This role involves regular standing, walking, sitting, and the use of hands for handling or operating equipment. The employee may also need to reach, climb, balance, stoop, kneel, crouch, and maintain visual, verbal, and auditory communication in a standard office environment and while working independently from remote locations. The employee must occasionally lift and/or move up to 20 pounds.  This position requires the ability to travel independently overnight and/or work after hours as required by travel schedules or business needs.

#LI-HYBRID #NC1

Physician Careers with The Oncology Institute 

About the Role

The Oncology Institute of Hope & Innovation (TOI) is seeking a Board-Certified or Board-Eligible Hematology & Oncology Physician to join our growing Vista, CA practice. This is an opportunity to deliver high-quality, patient-centered cancer care in a community-based setting with strong clinical support, predictable income, and leadership growth potential.

At TOI, physicians practice at the top of their license while being supported by an integrated care model designed to reduce administrative burden and allow you to focus on patient care.

Practice & Clinical Support Model

• Established referral network with a growing patient panel
• On-site infusion services
• Dedicated APP, Nursing, and Medical Assistant support
• Multidisciplinary care teams and tumor board collaboration
• Technology-enabled workflows to support efficient, high-quality care
• Shared call structure with call coverage (Q4 – every 4 weekends)

Compensation Structure

• Competitive base salary starting at $500,000+ with clearly defined incentive opportunities. Salary dependent upon experience and location.
• wRVU incentive model rewards thoughtful, sustainable growth by recognizing productivity alongside quality of care, patient experience, and sound clinical documentation.
• Typical physicians can achieve $650,000+ in total cash compensation once established
• Transparent compensation discussions early in the recruitment process

Career Growth & Leadership Opportunities

• Pathways to Medical Director and clinical leadership roles
• Opportunities to participate in clinical trials and research initiatives
• Principal Investigator (PI) opportunities for interested physicians
• Ability to contribute to program development and clinical strategy

Benefits & Lifestyle Support

• Guaranteed Sign-On Bonus: You will receive a $100,000 guaranteed sign-on bonus
• 3 CME days + $2,500 annually
• Medical, dental, vision, life, and disability insurance
• Malpractice coverage
• Paid time off
• Relocation assistance and student loan repayment support
• Licensing: Out of state? Your state license application & initial fee paid by The Oncology Institute
• License Renewals are paid by TOI

A Growing Network, Built for Sustainability

TOI continues to thoughtfully expand its clinic footprint across California to meet growing patient demand. New clinic development is paired with investments in clinical staffing, infusion capacity, and physician leadership, creating long-term stability and meaningful opportunities for physicians who want to grow with the organization.

Why Physicians Choose TOI

• Predictable compensation with strong earning potential
• Supportive, physician-led clinical environment
• Community oncology focus with access to advanced care models
• Leadership opportunities without academic bureaucracy
• Mission-driven organization committed to compassionate, accessible cancer care

Why Vista: 

• Access to a growing, underserved patient base: Vista sits in North San Diego County, where demand for oncology services continues to rise—offering physicians the opportunity to make a meaningful impact while building a robust and rewarding practice.
• Collaborative regional healthcare network: The area is supported by reputable hospitals and specialty groups, enabling strong referral patterns, multidisciplinary care, and opportunities to participate in advanced cancer treatment and clinical initiatives.
• Exceptional lifestyle and work-life balance: With its mild year-round climate, proximity to beaches, and less congestion than central San Diego, Vista offers an ideal environment for physicians seeking balance without sacrificing professional opportunity.
• Family-friendly and affordable relative to coastal hubs: Compared to nearby coastal cities, Vista provides more attainable housing options, good schools, and a welcoming community—making it an attractive place to settle long-term.

About The Oncology Institute of Hope & Innovation

TOI is a leading community-based oncology network dedicated to providing high-quality, value-based cancer care. Our integrated model combines clinical excellence, innovation, and compassion to improve outcomes for patients while supporting physician well-being and professional growth.

Next Steps

Physicians interested in a confidential conversation are encouraged to apply. Our recruiting team is committed to a transparent, efficient process and early compensation discussions.

Not ready to apply? Please reach out to physiciancareers@theoncologyinstitute.com for an exploratory conversation with our team. 

ESSENTIAL JOB FUNCTIONS:

The Senior Director, Medical & Regulatory Writing serves as subject matter expert on clinical protocols, protocol amendments, clinical study reports, Investigator’s Brochures, and briefing books. May also provide guidance on document strategy for more complex dossiers for regulatory submission such as IND and NDA/BLA filings. This role leads and is accountable for the Medical Writing and Clinical Trial Transparency & Disclosure functions. The position requires the ability to work collaboratively with cross-functional teams in a fast-paced environment. The qualified candidate will also have experience in management of external vendors and the development of operational process improvements such as work practice documents, SOP development and updates, and document templates. There will need to be a very strong understanding of document timelines as planning is critical.

• Provides leadership, strategy, and oversight of the Medical & Regulatory Writing team.
• Serves as subject matter expert in preparing clinical regulatory documents through all phases clinical research.
• Represent medical writing in cross-functional team meetings.
• Collaborate with department heads and staff members of cross-functional groups, including clinical research, clinical operations, data management, biostatistics, regulatory affairs, and medical affairs as necessary to deliver documents with high quality on time.
• Adhere to established regulatory standards, including ICH-E3 guidelines and company SOPs.
• Support the development, improvement and maintenance of medical writing work practice documents, SOPs, and document templates to ensure consistency and efficiency.
• Oversight of vendors including contract writers, QC reviewers, and document formatters.
• Must have proficiency in the use of EndNote or RightFind Cite It software for the citation of literature references and creation of list of references in Word documents.
• Maintain current knowledge of industry trends and best practices for medical writing
• Performs other duties as assigned

JOB SPECIFICATIONS:

• Bachelor’s, Master’s or PhD Degree in scientific, medical, clinical discipline or related field is required. Masters or Ph.D. degree is preferred.
• Strong track record of people management and delegating work.
• 12+ years of relevant industry experience as a medical writer in a pharmaceutical, biotech, or CRO environment. Oncology experience preferred.
• Must have experience authoring clinical study reports, protocols, protocol amendments, Investigator’s Brochure. Experience authoring and managing briefing books is a plus.
• Experience in regulatory submissions (clinical study reports) presented to regulatory authorities a plus
• Strong understanding of federal regulations, Good Clinical Practices, and ICH guidelines a plus
• Project management skills as related to medical writing.
• Ability to manage complex writing projects with minimal supervision.
• Must have the ability to edit text for brevity and clarity.
• Ability to understand, interpret and present complex clinical data.
• Must be highly detail oriented.
• Ability to coordinate multiple documents while effectively managing timelines.
• High degree of independence in decision making and problem solving.
• Leads decision-making across multiple programs or areas, setting direction and making strategic trade-offs that impact cross-functional execution and outcomes.
• Drives cross-functional alignment across multiple programs, influencing stakeholders to shape strategy and ensure cohesive execution across functions.
• Understanding of FDA and ICH regulations and guidelines.
• Familiarity with eCTD-compliant templates and with the use of document formatting tools such as ISI writer, Liquent Smart Desk, Acumen Stylus, or other formatting tools.
• Must be an expert with MS Word and have a solid working knowledge of MS Excel, MS PowerPoint, and MS Project.
• Experience in use of an EDMS such as Documentum, Core Dossier, or Veeva.

The base range for this role at the Senior Director level is $265,000 - $306,000 per year. Individual pay may vary based on additional factors, including, and without limitation, job-related skills, experience, work location, and relevant education or training. Kura's compensation package also includes generous benefits, equity, and participation in an annual target bonus.

#LI-RM1

Please note that this position is based in San Diego, CA or Princeton, NJ. Acadia's hybrid model requires this role to work in our office three days per week on average.

Position Summary 

Acadia Pharmaceuticals is seeking a seasoned and strategic Health Economics and Outcomes Research (HEOR) leader to serve as Senior Director, HEOR. In this critical role, you will lead the development and execution of comprehensive value evidence strategies that demonstrate the clinical, economic, and humanistic value of Acadia’s therapies across their lifecycle, from development through commercialization and global market access.

As the demand for high quality real world evidence and outcomes research continues to grow, this role will be central to supporting health technology assessments, payer decision making, reimbursement, and product differentiation. You will oversee the generation and dissemination of HEOR evidence, including real world evidence, economic modeling, and clinical outcomes assessments, to support access and adoption across global markets.

The Senior Director, HEOR will be responsible for shaping and communicating the value story for assigned products or indications, leading the development of global value dossiers, economic models, and HTA strategies that clearly articulate the benefit of Acadia’s therapies to patients, healthcare systems, and population health decision makers. This role requires close collaboration with Commercial, Market Access, Clinical Development, Medical Affairs, Regulatory, and other cross functional partners to ensure HEOR strategies are aligned with scientific objectives, business priorities, and regulatory expectations.

The ideal candidate brings deep expertise in outcomes research methodologies, strong scientific and strategic judgment, and the ability to lead complex, cross functional initiatives in a fast paced, global environment. This position offers a unique opportunity to shape evidence strategies that influence access, reimbursement, and ultimately patient outcomes for therapies addressing significant unmet medical needs.

Primary Responsibilities

• Build and implement the strategy for HEOR, including RWE and HTA evidence generation & dissemination within an assigned area for in-line and pipeline assets.
• Lead delivery of value evidence generation strategies throughout the product life cycle.
• Oversee and guide the development and implementation of patient-reported outcomes (PRO) and COA endpoints strategy.
• Ensure the work delivered by HEOR in the assigned area aligns with R&D and corporate goals.
• Represent HEOR on various cross-functional teams in commercial/clinical/medical areas.
• Direct and implement relevant HEOR initiatives with external entities.
• Contribute to the development and execution of overall and HEOR-specific publication plans.
• Establish an integrated HEOR plan aligned with Commercial, Market Access, and Scientific objectives.
• Other duties as assigned.

Education/Experience/Skills

• Master’s degree in public health, economics, epidemiology, health services research or HEOR-related field. 
• Targeting 12 years’ experience in the pharmaceutical or medical device industry; or, a Doctorate in health services research, pharmacy, medicine, public health, economics, and targeting 9 years’ experience in global biopharmaceutical or medical device industry. 
• Experience in outcomes research methodologies (retrospective observational cohort, cross-sectional studies, registries, etc.) to support product development and reimbursement efforts is required. 
•  Must have experience with the execution of scientifically robust qualitative and quantitative studies, development and validation of COA measures, including assisting clinical development teams in implementing COAs in clinical trials to measure patient-relevant endpoints.

Key Skills:

• Understanding of the global healthcare environment, clinical research processes, global regulations, and ethical guidelines.
• Rare disease or CNS experience with interactions with US and ex-US reimbursement agencies is preferred.
• Highly developed communications skills (written/verbal) and interpersonal savvy.
• Proven meeting planning and team facilitation skills.
• Ability to create, track, plan, and communicate project timelines to team members, and maintain budgets.
• Ability to create, track and plan timelines and budgets.
• Ability to support multiple projects while being well-organized, have strong time management skills, and attention to detail.
• Excellent organization and multi-tasking skills.
• Ability to accommodate shifting priorities, demands and timelines.
• Ability to learn, understand and apply new technologies, strategies and approaches that enhance the team’s ability to achieve goals and meet timelines/deliverables.
• Knowledge of regulatory guidance documents and scientific guidelines (FDA guidance; FDA qualification documentation; dossier outline; EMA guidance resources; ISPOR Task Force Documents, etc.).
• Understanding of instrument development and validation process.
• Strong computer skills (Microsoft Office, etc.) and knowledge of database management (Veeva Vault, etc.).
• Must be able and willing to travel (up to approximately 40%) for conferences, meetings, and HEOR project or team-management related business.

Physical Requirements

This role involves regular standing, walking, sitting, and the use of hands for handling or operating equipment. The employee may also need to reach, climb, balance, stoop, kneel, crouch, and maintain visual, verbal, and auditory communication in a standard office environment and while working independently from remote locations. The employee must occasionally lift and/or move up to 20 pounds.  This position requires the ability to travel independently overnight and/or work after hours as required by travel schedules or business needs.

#LI-SW1

#LI-Hybrid

Please note that this position can be based in Princeton, NJ OR San Diego, CA. Acadia's hybrid model requires this role to work in our office an average of 3 days per week.

Position Summary:

Responsible for the chemical process development, implementation and management of robust, cost effective, and safe processes for the manufacture of APIs from the research stage, through clinical development and marketing approval. Will be responsible for the technical development, support, innovative solutions and commercialization of drug substances using an external network of providers. This position is integral to the advancement of ACADIA’s growing portfolio of drug candidates, and will provide technical oversight, expertise and guidance of externalized drug substance development related activities.

Primary Responsibilities:

• Lead scientific strategy for drug substance development, ensuring scalable, efficient, and compliant processes that meet clinical and commercial needs

• Oversee contract service providers (CSPs) to develop, optimize, and scale manufacturing processes from preclinical through commercialization

• Apply risk assessments and Quality by Design (QbD) principles to define design space and establish robust control strategies

• Develop end-to-end drug substance strategies supporting product quality, global regulatory approvals, and supply chain flexibility

• Manage technology transfer, outsourcing, and external manufacturing to build a reliable and scalable supply chain

• Establish, evaluate, and manage CSP partnerships, including contract negotiation, performance oversight, and issue resolution
  

• Ensure cGMP compliance, oversee deviations and change management, and partner with Quality and Regulatory to assess impact on filings

• Lead planning and execution of timelines, deliverables, and CMC documentation to support regulatory submissions and inspections
  
  
• Provide cross-functional leadership and technical expertise, supporting internal teams, governance forums, and external diligence activities

Education/Experience/Skills:

Ph.D. degree in Synthetic Organic Chemistry or other related scientific discipline. A minimum of 8 years of relevant progressive experience in API development and manufacturing in the pharmaceutical/biotechnology industry with a minimum of 5 years in a scientific role. An equivalent combination of relevant education and applicable job experience may be considered.

Requirements:

• Leadership experience in managing diverse project activities with contract CDMO facilities at different global locations

• Experience with global pharmaceutical/chemical development and manufacturing operations for development-stage small molecules, including upstream/downstream process development. Well-versed in drug substance manufacturing control strategies

• Highly knowledgeable with FDA and ICH guidelines relating to registration, quality and compliance with small molecule drug substance

• Awareness of scientific developments and opportunities in chemistry/chemical engineering

• Strong understanding of organic synthetic chemistry concepts and cross-functional understanding related to API development from pre-IND through NDA

• Chemistry Manufacturing Controls (CMC) expertise to prepare documents for regulatory filing (e.g. IND to NDA)

• Extensive knowledge of current Good Manufacturing Practices (cGMPs) and experience in chemical development for new drugs

• Excellent communication, interpersonal and presentation skills. Ability to effectively collaborate with and direct the work of others on assigned projects (including both internal teams and external collaborators)

• Skilled at negotiating with business partners/management and influencing senior level leaders regarding matters of significance to the organization. Demonstrated problem-solving abilities and conflict resolution skills

• Proficient at creating and communicating a clear vision among team members effectively aligning resources and activities to achieve functional area and/or organizational goals

Physical Requirements

This role involves regular standing, walking, sitting, and the use of hands for handling or operating equipment. The employee may also need to reach, climb, balance, stoop, kneel, crouch, and maintain visual, verbal, and auditory communication in a standard office environment and while working independently from remote locations. The employee must occasionally lift and/or move up to 20 pounds.  This position requires the ability to travel independently overnight and/or work after hours as required by travel schedules or business needs.

Please note that this position can be based in San Diego, CA OR San Francisco, CA OR Princeton, NJ. Acadia's hybrid model requires this role to work in our office three days per week on average.

Position Summary

The Associate Director, Trial Master File (TMF) Oversight & Inspection Readiness (IR) is responsible for leading the operational oversight of the TMF and supporting the framework that ensures Trial Master File integrity, sustained inspection readiness, and regulatory compliance within Clinical Operations.  This role leads TMF health governance, inspection preparedness, and risk identification processes to safeguard the organization during regulatory inspections and audits.  The Associate Director serves as the Clinical Operations lead for inspection defense, by advancing consistent standards, proactive risk visibility, and clear organizational insight into TMF integrity and inspection readiness.

Primary Responsibilities

TMF Oversight & Governance

• Establish TMF health oversight framework across studies, ensuring compliance with GCP and industry standards.

• Monitor TMF quality metrics across programs, ensuring completeness, timeliness, and accuracy of essential documents; Escalate any TMF metrics falling outside of KPIs to appropriate stakeholders for resolution and corrective action.

• Lead and share TMF best practices with internal and external stakeholders, as appropriate. Oversee TMF risk trending and remediation plans.

• Maintain inspection-readiness standards for documentation.

Inspection Readiness Leadership

• Develop and maintain a sustainable inspection readiness model, including development and maintenance of comprehensive inspection readiness tools, reference materials and coordinating training guidance to staff on preparation efforts for health authority inspections.

• Lead inspection storyboarding and narrative development. Coordinate inspection preparation activities. Lead designated Clinical Operations activities during regulatory inspections.

• Support post-inspection CAPA alignment, in partnership with Quality.

• Support Clinical Operations team on all inspection commitments, responses, post-inspection activities and implementation of corrective and preventative actions; provide lessons learned from mock and actual inspections. Ensure portfolio-level visibility of inspection risk.

Other Responsibilities

• Partner cross-functionally to align on audit and inspection strategy, as well as TMF platform integrity. Align with functional study teams on TMF accountability expectations. Maintain awareness of industry trends and developments to help define the future strategic direction for TMF and Inspection Readiness.

• Other responsibilities as required.

Education/Experience/Skills

Bachelor’s degree in life sciences or related field; Advanced degree preferred.  Targeting at least 8 years pharmaceutical industry and/or clinical research organization experience, with at least 5 years TMF experience in a leadership role.  Health Authority inspection and eTMF experience is required. An equivalent combination of relevant education and experience may be considered.

Key Skills

• Thorough understanding of GCP and ICH guidelines; thorough understanding of the drug development process.

• Knowledge and understanding of the current regulatory requirements (e.g., FDA, EMA, MHRA) in a global environment.

• Thorough understanding of the CDISC TMF Reference model; direct experience with the TMF Reference Model working group is preferred.

• Veeva Vault eTMF/CTMS experience preferred.

• Ability to lead, motivate, and influence others, including prior leadership experience, is strongly preferred.

• Adept at creating and communicating a clear vision among, effectively aligning resources and motivating stakeholders to achieve goals.

• Demonstrated analytical abilities and proficient planning and negotiation skills. Demonstrated technical, administrative and project management capabilities. 

• Strong interpersonal, organizational and workload planning skills along with excellent verbal and written communication skills.

• Demonstrated success with cross-functional collaboration and managing multiple assignments with timely and accurate output. Demonstrated problem-solving abilities, with strong attention to detail. 

• Able and willing to travel both domestically and internationally.

Physical Requirements

While performing the duties of this job, the employee is regularly required to stand; walk; sit; use hands to finger, handle, or feel; reach with hands and arms; climb or balance; stoop, kneel, crouch, see, talk or hear in a standard office environment and independently from remote locations. Employee must occasionally lift and/or move up to 20 pounds.  Ability to travel independently overnight and work after hours if required by travel schedule or business needs.

#LI-Hybrid #LI-SL1

Seeking talent near: Princeton, NJ : San Diego, CA

Position Summary:

The Associate Director, Business Development will work collaboratively with a variety of company functions including External Innovation (Acadia’s R&D Search and Evaluation team), Commercial, and Finance as well as external resources to review, landscape, identify and evaluate external assets to support and enhance the Acadia portfolio.  We are seeking an individual with strong analytical and evaluation skills including data gathering and analysis, financial modeling experience and related analysis, competitive intelligence and scientific/commercial analysis of companies and programs in the pharmaceutical and biotech industry, as well as experience with BD transactions.  The person in this role must have experience in identifying and analyzing the value of companies and programs within the pharmaceutical industry, building a business case for potential BD opportunities, and working with Executive management to implement corporate Business Development (BD) strategies. 

Primary Responsibilities:

• Conducts extensive searches using industry resources to identify and evaluate potential BD opportunities.
• Constructs forecasts, recommendations and strategic/tactical plans based on business data and market knowledge.
• Develop a solid business case and provide other general support for BD transactions including scientific, commercial and financial considerations.
• Conducts search efforts to identify business development acquisition or in-licensing opportunities.
• Role supports and coordinates activities related to the search, identification, competitive intelligence, and business case for potential transactions, working with the External Innovation and Commercial teams who lead the scientific and commercial assessments, which are incorporated into the overall deal package by BD.
• Performs in-depth evaluations, interpreting competitive landscape and analysis of financial data.
• Develops and manages complex revenue & cash flow NPV models and assist in production and testing assumptions related to overall commercial opportunity modeling (e.g., future markets, product performance, customers & compliance and competitors). Works with Finance to create forecasting and deal evaluation models.
• Maintains awareness and knowledge of product strategy to assess fit of potential candidates.
• Stays abreast of emerging healthcare & pharmaceutical industry trends and assess their potential impact on business strategies.

Education/Experience/Skills:

Targeting a minimum of 5 years of progressively responsible experience within consulting, venture capital or investment banking with a focus on valuation of and strategic transactions related to of therapeutics/companies in the pharmaceutical or biotech industry. M.D., advanced degree in a relevant scientific discipline (e.g., Ph.D.), or an MBA or functional equivalent, is required. Experience in the rare disease and CNS space. A combination of relevant education and applicable job experience may be considered.

Must possess:

• Scientific knowledge of industry sub-segments of CNS, Neurology or Orphan/Rare disease as well as industry functional areas of R&D, Clinical Development and Commercial/New Product Planning.
• Extensive experience developing and using Excel-based models including working on/developing complex financial models.
• Experience in competitive analysis, market research and analysis, and new product development needed.
• Expertise with Microsoft Office applications (Word, Excel, PowerPoint) with a strong focus on PowerPoint presentation skills
• Excellent analytical abilities: ability to draw conclusions and present recommendations on a variety of data.
• Ability to create and deliver influential large scale project communications with clarity, confidence and enthusiasm.
• Demonstrated ability to manage projects and time with multiple commitments/projects simultaneously.
• Superior written / verbal communication, organizational and analytical skills
• Critical thinking skills with the ability to get to the right level of granularity to balance speed of execution and facilitate optimal decision-making by executive management.
• Excellent financial analysis and research skills and ability to translate analyses into sound strategic recommendations.
• Ability to work in a results-oriented, project-driven, real-time team environment, prioritize projects and deliver quality results within tight time constraints.
• Ability to think strategically as well as to act tactically.
• Excellent database skills.
• Ability to travel.

Physical Requirements:

This role involves regular standing, walking, sitting, and the use of hands for handling or operating equipment. The employee may also need to reach, climb, balance, stoop, kneel, crouch, and maintain visual, verbal, and auditory communication both in a standard office environment and while working independently from remote locations. Employee must occasionally lift and/or move up to 20 pounds. This position requires the ability to travel independently overnight and/or work after hours as required by travel schedule or business needs.

Please note that this position is based in San Diego, CA. Acadia's hybrid model requires this role to work in our office three days per week on average.

Position Summary

The Associate Director will collaborate with the Clinical Data Management team by providing leadership and knowledge.  Assists the head of Data Management in directing the design, documentation, testing and implementation of clinical data collection studies, and clinical database reviews in support of company objectives.  Ensures that the data management systems are business ready and of appropriate quality to fulfill those objectives.  Focuses on the oversight of quality data deliverables within Acadia Data Management and projects with Contract Research Organizations (CROs).

Primary Responsibilities

• Participates in the collaboration and coordination with others to design and implement clinical protocols and data collection systems.
• Assists in identifying and resolving data management issues on assigned studies.
• Responsible for ensuring data management timelines are met within assigned studies, in-house or outsourced.
• Provides strategic input into protocol design focused on data management portions.
• May assist Biostatistics in development/review of Statistical Analysis Plans.
• Reviews and resolves data discrepancies for standardized data validation systems and procedures, when applicable.
• Supports data management requirements and deliverables for New Drug Application (NDA)/Marketing Authorisation Application (MAA), including integrated databases. 
• Aids in production of quality data deliverables to support regulatory submissions, publications and due diligence activities.
• Reviews clinical, regulatory and other documents, as needed, to assure data integrity and quality.
• Oversees projects that have been engaged with CROs, as well leads and manages internal projects.
• Oversees and manages final data management electronic Trial Master File (eTMF) for assigned studies.
• Assists with the development of standards and process documentation, including Standard Operating Procedures and Work Instructions.
• Assures compliance with industry quality standards, guidelines and procedures.
• Assists in the selection and evaluation of new personnel to ensure the efficient operation of the function.
• May assist in the career development of Data Management personnel.  Position may have direct reports. May assist with input into corporate and department budget process and management.
• Other responsibilities as assigned.

Education and Experience

• Bachelor’s degree in Life Sciences, Mathematics or related field.  Targeting 8 years of progressively responsible experience within the pharmaceutical, biotech or CRO industry.  An equivalent combination of relevant education and experience may be considered.
• Previous experience in data management from protocol concept through database lock and clinical study report finalization.
• Knowledge of medical terminology.
• Knowledge of coding dictionaries (Medical Dictionary for Regulatory Activities -MedDRA, WHO Drug)
• Excellent verbal and written communication skills as well as interpersonal and organizational skills
• Proficiency in MS Office applications.
• Proficiency with data management systems and supporting statistical programs (e.g., SAS),
• Knowledge of database design and database concepts.
• Skilled at cross-functional/department communications to gain cooperation of others.
• Proven skill at effectively leading a cooperative team effort and organizing resources to achieve team goals.
• Able to make and prioritize process and resource decisions based on overall team needs.
• Must be able and willing to travel on occasion.

Physical Requirements

This role involves regular standing, walking, sitting, and the use of hands for handling or operating equipment. The employee may also need to reach, climb, balance, stoop, kneel, crouch, and maintain visual, verbal, and auditory communication in a standard office environment and while working independently from remote locations. The employee must occasionally lift and/or move up to 20 pounds.  This position requires the ability to travel independently overnight and/or work after hours as required by travel schedules or business needs.

#LI-HYBRID #LI-SL1

Please note that this position can be based in Princeton, NJ, OR San Diego, CA, OR San Francisco, CA. Acadia's hybrid model requires this role to work in our office three days per week on average.

Position Summary

This role is responsible for supporting Clinical Operations’ management objectives to perform clinical trials that are of high quality, and that are delivered to agreed timelines and budget. This role manages clinical operations processes including project planning, budget, resource management, and contract research organization management. This role serves as a key contact and resource for Clinical Study Managers, CRA’s and Clinical Trial Assistants. Responsible for ensuring that clinical studies are carried out and delivered according to GCP and company SOPs. Assists with the creation and implementation of policies. Works cross-functionally to ensure that the teams provide required inputs and receive updates to carry out clinical trials in an effective manner.

Primary Responsibilities

· Manages clinical operations teams and represents clinical operations on multi-function projects teams, internally/externally. Works with clinical investigators, other roles, and Clinical Service Providers (CSP) to develop, execute, and deliver clinical studies/programs that are of high quality.

· Ensures quality delivery of study enrollment within agreed budgets and timelines.

· Participates in the design/review of clinical protocols, case report forms, tools and tracking systems, and IXRS systems.

· Develops and manages relationships with critical and non-critical 3rd party vendors and clinical site staff; maintains ongoing documentation, performs risk analyses, and may participate in due diligence and audit reviews.

· Effectively communicates project status and issues to management and the team.

· Prepares/oversees the preparation of all applicable documents required for the conduct of the study (Project Plan, Risk Management Plan, Monitoring Plan, Trial Master File (TMF)) etc.

· Manages and reviews the work of Contract Research Organization (CRO) to ensure that tasks are performed to scope and budget.

· Liaises with other functional groups to ensure that timelines, budgets, and study objectives are met.

· Liaises closely with Clinical GCP group to ensure that quality metrics are met throughout a trial.

· Oversees clinical study budgets.

· Provides day-to-day direction to Study Managers and Clinical Trial Assistants to carry out their work.

· Ensures compliance with good clinical practices (GCP), good documentation practices (GDP), and regulatory guidelines.

· Recommends and implements innovative process ideas to positively impact clinical trials management.

· Other responsibilities as assigned.

Education/Experience/Skills

Bachelor’s degree in life sciences or related field. Targeting 8 years’ progressively responsible pharmaceutical experience with a focus on clinical trials and late phase development. Leadership experience and CNS therapeutic experience preferred. An equivalent combination of relevant education and applicable job experience may be considered.

Key Skills:

· Knowledge and understanding of Good Clinical Practices (GCP) and other Clinical Trials Regulations and guidelines.

· Experience developing clinical protocols, Standard Operation Procedures (SOP), Clinical Study Reports, and other documents to support New Drug Application (NDA).

· Demonstrated ability to successfully develop, implement, and manage clinical trials.

· Practical experience in clinical trial strategies, methods, and processes; knowledge of clinical trial design.

· Demonstrated technical, administrative, and project management capabilities.

· Strong interpersonal, organizational, and workload planning skills, along with excellent verbal and written communication skills.

· Proficient computer skills, including Microsoft Word and Excel.

· Skilled at negotiating with business partners or management and influencing leaders regarding matters of significance to the department or segments of the organization.

· Adept at creating and communicating a clear vision among team members effectively aligning resources to achieve functional area goals.

· Ability to manage multiple priorities and work cross-functionally in a fast-paced environment.

· Must be willing and able to travel both domestically and internationally.

#LI-HYBRID #LI-CA1

Seeking talent near: Princeton, NJ ; San Diego, CA

Position Summary

The Associate Director in the Early Stage Drug Product Development organization at Acadia is responsible for the development of pharmaceutical formulations primarily intended for early-stage clinical trials and preclinical animal studies. This role also supports drug discovery teams by assisting in the selection of optimal drug candidates through detailed physicochemical characterization and assessment of compound properties. The incumbent will focus on formulation strategies tailored to early development phases, ensuring that candidates are suitably prepared for initial safety and efficacy evaluations. Additionally, collaboration with research scientists and external partners is essential to address technical challenges and advance promising compounds toward clinical readiness.

The incumbent will be responsible for management of activities relating to the above at the Contract Service Providers (CSPs) and will contribute both internally and externally in resolution of complex technological issues The role will be critical in ensuring that we select developable drug candidates, reduce risk and accelerate the introduction of new chemical entities into the Acadia pipeline.

Primary Responsibilities
 

• Designs and develops pharmaceutical formulations to support early stage clinical trials, providing acceleration options such as on-site compounding and impromptu type of drug products.
• Evaluate and validate new drug product CSPs (Contract Service Providers) to support development, oversee operations at existing suppliers.  Initiate and manage supplier contract agreements as necessary.
• Coordinate and supervise the development of clinical formulations and finished dosage forms at CSPs.  Serves as person-in-the plant at the CSP sites.
• Plans project-related scientific and technical activities, e.g. interpretation of results, evaluation of data, formulates relevant and scientifically based conclusions, writes and presents technical reports.
• With Translational Sciences teams, plans conduct of preclinical and toxicological studies and develops requisite formulations for the same considering developability of the new drug candidates.
• Develops phase appropriate formulations for new drug candidates in FIH, Phase 1 and POC studies employing resource sparing approaches such as compounded formulations and/or on-site preparations.
• Conduct physicochemical characterizations of the new drug candidates to support developability assessments.
• Authors and reviews technical reports and documents suitable for regulatory submissions. Reviews MBRs, BPRs, development reports and relevant documents prepared by CSPs.
• Liaises with the CMC team, late-stage formulation team, and formulation development management to establish the development strategy for formulation of the new drug candidates.
• Adheres to cGMP work practices and works closely with the Quality Assurance to ensure strict compliance with applicable GXP procedures and compliance requirements. Collaborates with regulatory teams in preparation of the health authority submissions for the early clinical trial applications (e.g. IND, CTA, IMPD)
• Other responsibilities as assigned.

Education/Experience/Skills

Advanced degree in Pharmaceutical Sciences, Chemistry, Chemical Engineering, Materials Science, or related field. An equivalent combination of relevant education and applicable industry experience may be considered.  A minimum of 10 years’ experience in progressively responsible roles in formulation and manufacturing process development with some experience in leadership role desired.  Demonstrated success in the field of formulations and dosage form development.   Experience authoring technical reports and CMC sections for regulatory filings. 

Must possess:

• Comprehensive understanding of the physicochemical characterization of new drug candidates to assess developability, formulations for early stage clinical studies, and dosage form formulation and package development.
• Extensive knowledge of cGMPs.
• Skilled at managing CSPs.
• Demonstrated verbal and written communication skills.
• Adept at effectively aligning resources across multiple functional areas to achieve functional area goals.
• Flexibility to travel domestically and internationally.

Physical Requirements:

While performing the duties of this job, the employee is regularly required to stand; walk; sit; use hands to finger, handle, or feel; reach with hands and arms; climb or balance; stoop, kneel, crouch, see, talk or hear in a standard office environment and independently from remote locations. Employee must occasionally lift and/or move up to 20 pounds. Ability to travel to domestic and international locations is required.

#LI-HYBRID #NC1 

Please note that this position can be based in San Diego, CA OR San Francisco, CA OR Princeton, NJ. Acadia's hybrid model requires this role to work in our office three days per week on average.

Position Summary

The Associate Director will be responsible for the oversight of Translational Science preclinical safety assessment/toxicology deliverables, with a clear understanding of functional interdependence and critical path activities. The role will contribute to the research and/or development of the products, projects, and programs in support of the pipeline.  Collaborate cross‑functionally to conduct basic research and development, including designing and overseeing preclinical safety and toxicology studies in support of diverse projects and long-term company objectives.  Ensure timely and effective communication of project status and issues to drive alignment and successful completion of team goals and deliverables.

Primary Responsibilities

• Plans experimental safety assessment/toxicology programs to include design, logistics, resource allocation, schedules. Identifies critical support needs, and other necessary details to implement the program(s).

• Provides oversight on scientific management of preclinical safety assessment/toxicology studies supporting early drug development spanning lead optimization through IND and NDA submissions and nonclinical post marketing approval requirements.

• Monitors CROs for quality and compliance in the conduct of preclinical safety assessment/toxicology studies.

• Manages vendors and consultants, encompassing study design, detailed coordination of study execution, overview of quality compliance, and scientific rigor.

• Reviews and contributes to preparation of toxicology reports.

• Maintains oversight of test compound delivery, shipment and supply requirements.

• Works cross functionally on projects including an understanding of when broader discussion is required and the organization ad hoc working groups as needed to move project activities forward.

• Communicates project status and proactively identifies issues to ensure that project team goals and regulatory deliverables are met.

• Provides guidance to team members to objectively assess and resolve preclinical safety assessment/toxicology project issues to improve project effectiveness.

• Other duties as assigned.

Education/Experience/Skills

BS or MS in a relevant discipline or a related field. Targeting 8 years of relevant experience in pre-clinical safety assessment/toxicology supporting drug development within the pharmaceutical or biotech industry.  DABT Certification strongly preferred. An equivalent combination of relevant education and experience may be considered.

Key Skills:

• Understanding of the drug development process and the principles, concepts, practices, and standards of executing preclinical safety assessment/toxicology strategies.

• Knowledge in the tools and procedures of preclinical safety assessment/toxicology experimentation, including the various experimental designs, statistical tools of data analyses, software applications available for data manipulation and presentation, and instrumentation pertinent to the research and ability to evaluate the advantages and disadvantages of each, in terms of applicability to the research at hand.

• Knowledge of the preclinical study types necessary during drug development, including acute and chronic toxicology, safety pharmacology, developmental and reproductive toxicology, genotoxicity and carcinogenicity.

• Experience working in cross-functional project teams and in a semi-virtual environment including CROs and academic collaborations.

• Study monitoring experience on Good Laboratory Practices (GLP) safety assessment/toxicology studies at CROs.

• Experience in the composition and review of preclinical safety assessment/toxicology reports with respect to accuracy, quality and compliance.

• Knowledge and understanding of GLP, ICH and FDA guidance, and other relevant regulations and guidelines.

• Demonstrated skills and abilities in influencing, facilitation, development, and problem solving. Ability to elicit cooperation from a wide variety of sources and to be influential, encouraging and motivating.

• Excellent communication, presentation, consultative, partnership, and interpersonal skills. Self-motivated and able to work with limited supervision. 

• Ability to learn, understand and apply new technologies, strategies and approaches that enhance the team’s ability to achieve goals and meet timelines/deliverables.

• Must be able and willing to travel as needed.

Physical Requirements

This role involves regular standing, walking, sitting, and the use of hands for handling or operating equipment. The employee may also need to reach, climb, balance, stoop, kneel, crouch, and maintain visual, verbal, and auditory communication in a standard office environment and while working independently from remote locations. The employee must occasionally lift and/or move up to 20 pounds.  This position requires the ability to travel independently overnight and/or work after hours as required by travel schedules or business needs.

#transmed

#LI-Hybrid #LI-SL1

Please note that this position can be based in San Diego, CA OR San Francisco, CA OR Princeton, NJ. Acadia's hybrid model requires this role to work in our office three days per week on average.

Position Summary

Responsible for the oversight of Translational Medicine preclinical safety assessment/toxicology deliverables, with a clear understanding of functional interdependencies and critical path activities.  The role will contribute to the research and/or development of the products, projects, and programs in support of the pipeline. Conducts and collaborates with others on basic research and development including preclinical safety assessment/toxicology studies supporting various projects relevant to long-term objectives of the company. Conducts and collaborates with others on basic research and development including designing and monitoring preclinical safety assessment/toxicology studies supporting various projects relevant to long-term objectives of the company. Responsible for the communication of project status and issues and develops strategies to ensure project team goals and deliverables are met.

Primary Responsibilities

• Plans experimental safety assessment/toxicology programs to include design, logistics, resource allocation, schedules.  Identifies critical support needs, and other necessary details to implement the program(s).

• Provides oversight on scientific management of preclinical safety assessment/toxicology studies supporting early drug development spanning lead optimization through IND and NDA submissions and nonclinical post marketing approval requirements.

• Monitors CROs for quality and compliance in the conduct of preclinical safety assessment/toxicology studies.

• Manages vendors and consultants to complete Translational Medicine safety assessment/toxicology studies for the various programs.

• Responsible for preparation and review of reports and regulatory documents for IND and NDA submissions. Explore innovative approaches to enhance efficiency of toxicology evaluations.

• Supports business development related nonclinical Tox/ADME assessments and due diligence projects by assessing available study data and regulatory submissions, identifying gaps, defining additional nonclinical study plans and test compound requirements, and developing overall project timelines and associated budgets.

• Supports Impurity/Degradant safety assessment reviews requested by Chemistry, Manufacturing, and Controls (CMC) groups, involving public domain literature reviews, evaluating structure activity relationships using in silico databases, and competitive intelligence sources.

• Works across functional areas on projects including lleading and participation in team and sub-team meetings and organizing ad hoc working groups as needed to move project activities forward. 

• Communicates project status and issues and ensures project team goals and regulatory deliverables are met. Clearly presents data, interpretation and recommendations to R&D leadership.

• Provides guidance to team members to objectively assess and resolve preclinical safety assessment/toxicology project issues to improve project effectiveness.

• Other duties as assigned.

Education/Experience/Skills

PhD or DVM in a relevant discipline or related field.  Targeting 10 years of relevant experience in pre-clinical safety assessment/toxicology supporting drug development experience within the pharmaceutical or biotech industry.  DABT Certification strongly preferred.  An equivalent combination of relevant education and experience may be considered.

Key Skills:

• Advanced understanding of the drug development process and the principles, concepts, practices, and standards of executing preclinical safety assessment/toxicology strategies.

• Broad knowledge in the tools and procedures of preclinical safety assessment/toxicology experimentation, including the various experimental designs, statistical tools of data analyses, software applications available for data manipulation and presentation, and instrumentation pertinent to the research. Through a complete understanding of the tools and design methods, able to evaluate the advantages and disadvantages of each, in terms of applicability to the research at hand.

• In depth knowledge of the preclinical study types necessary during drug development, including acute and chronic toxicology, safety pharmacology, developmental and reproductive toxicology, genotoxicity and carcinogenicity.

• Experience managing cross-functional project teams and working in a semi-virtual environment including CROs and academic collaborations.

• Specific direct study monitoring experience on Good Laboratory Practices (GLP) safety assessment/toxicology studies at CROs.

• Experience in the composition and review of preclinical safety assessment/toxicology reports with respect to accuracy, quality and compliance.

• Knowledge and understanding of GLP, ICH and FDA guidance, and other relevant regulations and guidelines.

• Demonstrated skills and abilities in leading teams and sub-teams, coaching, influencing, facilitation, development, and problem solving. Passion for science and teamwork with self-motivation and ability to work with limited supervision.

• Excellent communication, presentation, consultative, partnership, and interpersonal skills. Ability to elicit cooperation from a wide variety of sources and to be persuasive, encouraging and motivating.

• Ability to learn, understand and apply new technologies, strategies and approaches that enhance the team’s ability to achieve goals and meet timelines/deliverables.

• Willing and able to travel as needed.

Physical Requirements

This role involves regular standing, walking, sitting, and the use of hands for handling or operating equipment. The employee may also need to reach, climb, balance, stoop, kneel, crouch, and maintain visual, verbal, and auditory communication in a standard office environment and while working independently from remote locations. The employee must occasionally lift and/or move up to 20 pounds.  This position requires the ability to travel independently overnight and/or work after hours as required by travel schedules or business needs.

#transmed

#LI-Hybrid #LI-SL1

Please note that this position can be based in San Diego, CA OR San Francisco, CA OR Princeton, NJ. Acadia's hybrid model requires this role to work in our office three days per week on average.

Position Summary

The Executive Director will lead the design and implementation of disease and drug mechanism of action (MoA) studies to advance therapeutics into and through clinical development. The position requires deep experience in translational sciences, proven leadership and mentoring skills, hands-on rare disease experience, strong understanding of clinical biomarker development, and a deep understanding of drug development from discovery through late-stage clinical studies.  The ability to synthesize complex biological concepts and data into clearly communicated actionable insights is critical, as is a track record of successful partnering with functions across the drug development paradigm. 

Primary Responsibilities

• Develop translational biology strategies to interrogate disease and drug MoA, implement and drive execution for candidate targets and therapeutics

• Lead nonclinical sciences function, mentor scientists across translational sciences

• Partners with colleagues across the drug development paradigm to develop and test hypotheses designed to advance target and candidate molecule evaluation through various stages of development

• Partner with Translational Science colleagues to develop preclinical strategies supporting indication selection, PK/PD analyses, and mechanistic development for successful IND filing and clinical development

• Synthesize, analyze and integrate complex biological data, providing clear and actionable insights to drive drug development decisions

• Identify, evaluate and leverage cutting-edge technologies to expedite early-stage program development & success

• Identify and manage CROs and build strong collaborative relationships with Acadia partners to maximize the application of complementary areas of expertise

• Present programs and data for asset team, governance and senior / executive management review

• Contribute, as author and strategist, to document generation for preclinical studies & clinical protocols, clinical study reports, statistical analysis plans, research partnerships, regulatory materials (IB, IND, NDA, etc.) and publications

• Perform other responsibilities as assigned

Education/Experience/Skills

PhD in life science or related field.  Targeting 15 years of progressively responsible experience in drug development within the pharmaceutical or biotech industry.  An equivalent combination of relevant education and experience may be considered.

Key Skills:

• Strong cross-functional leadership with a proven ability to build collaborative, high-performing teams and represent nonclinical sciences across Translational Sciences and program teams
  
  
• Hands-on experience across drug discovery, preclinical development, and clinical-stage programs (Phase 1–3), including rare disease
  
  
• Demonstrated success leading programs through IND filing, with deep expertise in small molecule INDs and regulatory submissions (IND, NDA, BLA)
  
  
• Expertise in preclinical  (MoA) analysis, indication selection, and supporting clinical development strategies
  
  
• Strong understanding of clinical biomarker strategy and development
  
  
• Ability to analyze complex, multifactorial datasets, with computational literacy and collaboration with computational biology; bioinformatics integration experience is a plus
  
  
• Effective communicator with high emotional intelligence; skilled in presenting complex data to senior leadership and influencing stakeholders
  
  
• Proven ability to make decisions under uncertainty, aligning with timelines and organizational objectives
  
  
• Track record of driving performance through goal-setting, accountability, continuous improvement, and leading change across teams
  
  
• Able to manage multiple priorities in fast-paced environments, with flexibility for domestic and international travel; experience in neurology and across modalities (e.g., ASO, mRNA) is a plus

Physical Requirements

This role involves regular standing, walking, sitting, and the use of hands for handling or operating equipment. The employee may also need to reach, climb, balance, stoop, kneel, crouch, and maintain visual, verbal, and auditory communication in a standard office environment and while working independently from remote locations. The employee must occasionally lift and/or move up to 20 pounds.  This position requires the ability to travel independently overnight and/or work after hours as required by travel schedules or business needs.

LI #SL-1

Seeking talent near: Princeton, NJ, San Diego, CA

Position Summary

The (Senior) Director, Clinical Research will be a highly qualified and motivated individual who will have a leadership role in the development of Acadia programs for rare diseases and/or neurologic and neuropsychiatric disorders. This person will have extensive clinical and scientific knowledge and a strong network in the medical community, and successful experience in leading clinical programs.

Primary Responsibilities

• Create and execute global clinical development plans consistent with the Company’s strategic vision and mission.

• Ensure the optimal planning, implementation and interpretation of clinical studies, including synopsis/protocol development, medical monitoring, data analysis and writing of final reports. 

• Maintain and build productive relationships with investigators, thought leaders and centers of excellence across the scientific community, as well as with colleagues across the Acadia organization.

• Interact frequently with sites to support study awareness, patient recruitment, and quality of study conduct.

• Communicate appropriate program issues and results to key internal and external stakeholders.

• Support regulatory interactions, including the submission of regulatory documents and presentations.

• Provide clear and insightful clinical and scientific expertise to advance the successful transition of compounds from discovery to full development, and subsequently to life cycle management.

• Review business development opportunities, translating business needs to cost-effective development strategies that provide a competitive advantage and meet regulatory requirements.

• Comply with current local and international regulations, laws, scientific and regulatory guidance, Good Clinical Practices, and Acadia’s policies and procedures.

• Other duties as assigned.

Education and Experience

MD or equivalent required; Board Certified/Eligible strongly preferred.  Targeting 3-5 years of relevant medical/clinical practice, related research, or academic experience within the pharmaceutical industry.   Ideal candidate will have experience with medical monitoring, including clinical research, creating and implementing development plans and clinical studies.  An equivalent combination of relevant education and experience may be considered.

Key Skills:

• Applicable industry experience across several phases of development is strongly desired.

• Established relationships with thought leaders and investigators in depression and other mood disorders.

• Experience in rare disease and/or neurology strongly preferred.

• Demonstrated leadership to work well within a geographically diverse cross-functional team environment.

• Ability to work within a growing organization within the U.S. and to help the organization evolve over time into the world leader in rare diseases and neurologic and neuropsychiatric disorders.

• Experience interacting with senior leaders, including global regulatory agencies.

• Excellent verbal and written communication skills as well as interpersonal, management, and organizational skills.

• Demonstrated problem solving abilities and conflict resolution skills.

• Ability to engage in an open, constructive and continuous dialogue with the Company’s stakeholders.

• Highly motivated, self-driven and dependable.

• Willing and able to travel both domestically and internationally.

Physical Requirements

This role involves regular standing, walking, sitting, and the use of hands for handling or operating equipment. The employee may also need to reach, climb, balance, stoop, kneel, crouch, and maintain visual, verbal, and auditory communication in a standard office environment and while working independently from remote locations. The employee must occasionally lift and/or move up to 20 pounds.  This position requires the ability to travel independently overnight and/or work after hours as required by travel schedules or business needs.

#LI-HYBRID

About Tr1X

Tr1X is a private, clinical-stage biotechnology company focused on developing a novel class of regulatory T cell-based products to cure autoimmune and inflammatory diseases. Founded by industry experts, including the scientists who discovered Type 1 regulatory T (Tr1) cells, the company is developing a pipeline of off-the-shelf allogeneic cell therapies for autoimmune diseases with high unmet medical need. Our TRX cells are designed to mimic the function of naturally occurring Tr1 cells, which work to restore immune tolerance, stopping severe autoimmune and inflammatory disease in its tracks. Tr1X is the first company ever to use an allogeneic engineered Tr1 cell therapy in clinical trials. Tr1X is headquartered in San Diego, CA. For more information, please visit www.tr1x.bio.

Position Summary

The Senior Scientist, LNP Platform & Process Development (Scientist) is an experienced hands-on, lab-based, individual contributor that leads the design, development, and optimization of lipid nanoparticle (LNP) formulation and process development efforts supporting the Tr1X in vivo CAR-Treg platform. This individual plays a central role in developing and advancing the targeted lipid nanoparticle (tLNP) delivery systems from early research optimization through scalable, IND-enabling development.

This is a high-impact, foundational role within the company. The Scientist helps design and implement the LNP backbone of the platform and influence both short-term program execution and long-term manufacturability strategy. The Scientist brings deep hands-on expertise in LNP formulation and process development, strong analytical rigor, and the ability to thrive in a fast-paced startup environment.

Key Responsibilities

• Contribute to the design, development, and optimization of LNP formulations for mRNA delivery, including targeted LNP systems incorporating conjugated or functionalized lipids.
• Evaluate lipid composition, formulation parameters, and mixing conditions to optimize particle size, polydispersity, encapsulation efficiency, stability, release characteristics, and biological performance.
• Develop scalable, GMP-compatible manufacturing processes to support program advancement.
• Apply Quality by Design (QbD) principles and Design of Experiment (DoE) studies to study design and execution.
• Lead the development and optimization of analytical characterization methods (both in-house and at the external CDMO), including but not limited to DLS, fluorescence-based assays such as Ribogreen, HPLC/UPLC methods (CAD, UV, IP-RP, SEC, IEX), LC-MS, and endotoxin testing.
• Interpret analytical and stability data to establish meaningful correlations between physicochemical properties and biological function.
• Collaborate closely with platform biology teams to support in vitro and in vivo studies, prepare development reports and technical documentation, and contribute to technology transfer activities with external CDMO partners.
• Spearhead IND-enabling documentation and contribute to defining the long-term strategy for scalable LNP platform development.
• Perform other responsibilities as required based on business needs.

Required Qualifications & Experience

• Ph.D. in Chemical Engineering, Bioengineering, Pharmaceutical Sciences, Chemistry, or a related field with a minimum 4 years of relevant industry experience; or M.S. with 8+ years; or B.S. with 10+ years.
• Demonstrated in-depth expertise in LNP formulation and process development, including hands-on experience with microfluidic or scalable mixing technologies and downstream purification strategies such as TFF.
• Strong experience with analytical characterization of LNP systems and application of statistical design tools for process optimization.
• Highly organized, scientifically rigorous, and capable of independently driving projects while collaborating effectively in a multidisciplinary startup environment.
• Experience with mRNA therapeutics or nucleic acid delivery systems.
• Prior exposure to immunotherapy or cell therapy platforms preferred.
• Familiarity with regulatory expectations for CMC development and experience supporting technology transfer to external manufacturing partners preferred.
• Experience correlating formulation attributes with in vivo performance highly desirable.
  Ability to actively serve, collaborate, and develop relationships inside and outside the organization.
• Excellent written and oral communication skills.
• Strong analytical and problem-solving skills; great attention to detail and the ability to drive timely and fact-based decision making.
• Ability to function in a rapidly changing environment and handle multiple priorities.
• Demonstrated ability to partner, build trust, and cultivate positive working relationships with CDMOs.
• Experience with mRNA production and analytical quality control preferred.
• Effectively communicate changes and resolve issues with CDMOs.
• Lead and/or participate in cross functional development and manufacturing projects to ensure company objectives are met and exceeded.
• Ability to don and wear appropriate clean room attire and wear all required Personal Protective Equipment.

Other Requirements

• Legally authorized to work for any employer in the U.S.
• Position is on site in San Diego
• Travel may be required up to 10% of the time

The job responsibilities and requirements provided above are intended to describe the general nature of the work performed by individuals assigned to this job classification. It is not intended to be an exhaustive list of all duties and requirements. Tr1X retains the right to add, change, or delete duties, education, experience or any other requirements of the position at any time.

Working at Tr1X

At Tr1X, our team is united by a singular shared mission: to transform patients’ lives through breakthrough science. We are a group of skilled experts driven by urgency, innovation and a collaborative spirit. Our culture thrives on excellence, positivity, persistence and the agility to tackle new challenges head-on. With an unwavering commitment to patients, science and one another, we foster an environment where team members feel engaged, supported and empowered to make a meaningful impact. We envision a world where autoimmune diseases are not just being treated but are cured.

Base Pay Range Anticipated: $145,000 - $160,000

Tr1X considers a variety of factors to determine salary such as education, years of experience, time in the position level, training, knowledge, skills, geographic location, and the market value of the position.

Compensation and Benefits

Tr1X provides a fair and competitive total rewards program that includes base salary; discretionary annual target bonus; incentive stock options; 401(k) retirement plan with company contribution; health and welfare insurance plans for employees (and their families) that include medical, dental, vision, long-term and short-term disability, and life insurance; paid time off (PTO); and paid holidays.

Tr1X embraces a diverse, open, and inclusive environment and believes a strong culture connection is key to success. Tr1X is committed to fairness in recruitment, hiring, transfer, promotion or any other employment practice without regard to race, color, citizenship, national origin, ancestry, religion, sex, pregnancy, marital status, sexual orientation, gender, gender identity and expression, age, physical and medical disability, medical condition, genetic information, political affiliation, protected veteran status, or any other characteristic protected by law. If you are an individual needing assistance to complete an employment application or would like to request an accommodation, please contact the Human Resources department at careers@tr1x.bio.

Notice to Employment Agencies

The Tr1X talent acquisition program is managed through internal resources, and unsolicited referrals and resumes are not accepted from employment agencies, unless advance written authorization is granted from the human resources department. Tr1X shall not be liable for any fees arising from any unsolicited or unauthorized candidate information received relative to position vacancies.

The Clinical Trial Manager (CTM) is responsible for the oversight and management of all clinical operational activities at the trial and site level. The CTM will interact well with the Heartflow Clinical Research staff and collaborate effectively with Heartflow onsite and field staff, clinical research coordinators, principal investigators, and vendors to aid in ensuring clinical studies meet or exceed timelines and maintain high quality standards. The CTM will have demonstrated experience with clinical research study execution, exceptional organizational skills, excellent attention to detail, and will be comfortable working in a fast- paced start-up culture.

Job Responsibilities:

• Participates in clinical research activities including management of clinical study sites, management of study documentation, vendor management, and completion of project management tasks
• Develops clinical trial timelines, enrollment projections, and instructional materials in support of trial execution, including project, communication, monitoring, recruitment, risk mitigation, and contingency plans
• Participates in and leads process improvement activities within the department and cross functionally, including SOP development
• Conducts study start-up activities including the development of protocols, informed consent forms, source document worksheets, training presentations, etc.
• Reviews site regulatory documents (informed consents, IRB approvals, research agreements) to ensure compliance with study requirements and GCPs
• Maintains effective working relationships with investigators/investigational site research coordinators, and vendors including core labs and data management
• Perform other duties as required for successfully completing studies, as necessary

Skills Needed:

• Ability to work in a smaller team environment with a willing, all hands on deck attitude
• Ability to manage multiple tasks and be comfortable working in an environment with shifting priorities
• High attention to detail, accuracy, and quality and able to effectively prioritize multiple projects
• Knowledge of ICH Guidelines, US FDA, and European clinical trial requirements and regulations
• Excellent written and oral English communication skills required
• Proficiency in computer programs and specifically in Microsoft office tools including Word, Excel and PowerPoint

Educational Requirements & Work Experience:

• Bachelor’s degree in science or health related field
• Demonstrated 5 years minimum relevant experience required
• Experience in cardiovascular medical device clinical research a plus

Travel required: up to 25%

A reasonable estimate of the base salary compensation range is $110,000 to $150,000 (for San Francisco Bay Area) or $95,000 to $125,000 (for all other areas) and cash bonus. #LI-IB1

Position Summary

We are seeking a Vice President of Finance to lead financial operations for a rapidly growing, multi-entity medical practice and research organization across San Diego, Los Angeles, and Arizona.

This role requires a hands-on, technically strong CPA with deep expertise in healthcare revenue cycle management, including billing, collections, payer reconciliation, and multi-site financial performance optimization. The ideal candidate brings a strong command of GAAP, internal controls, and audit readiness, combined with the ability to drive revenue integrity, cash flow predictability, and scalable financial infrastructure in a high-growth environment.

You will partner directly with the CEO and physician leadership to build a best-in-class finance function, with particular focus on optimizing the end-to-end revenue cycle and ensuring financial accuracy, compliance, and scalability across all locations.

This role is exempt (salary) and full-time, working 40 hours per week, Monday through Friday, onsite/hybrid in San Diego, CA.

Key Responsibilities

Financial Leadership & CPA Ownership

• Serve as the lead CPA responsible for financial integrity, ensuring strict adherence to GAAP, tax regulations, and audit standards
• Own the monthly close process, ensuring timely, accurate financial statements across multiple entities
• Design and enforce robust internal controls, audit trails, and accounting policies
• Oversee external audits and manage relationships with auditors, tax advisors, and CPA firms
• Lead technical accounting decisions, including revenue recognition and entity structuring

Revenue Cycle Leadership

• Own the full healthcare revenue cycle, including:
  • Charge capture
  • Coding and billing accuracy
  • Claims submission and denial management
  • Collections and A/R optimization
  • Payer contract performance and reconciliation
• Establish and track core revenue cycle KPIs, such as:
  • Days in A/R
  • Net collection rate
  • Denial rates and recovery rates
  • Payer mix and reimbursement trends
• Partner with operations and clinical teams to identify leakage points and improve yield per visit/provider
• Implement technology-driven automation and reporting tools to streamline billing and collections
• Drive standardization of revenue cycle processes across all locations

Multi-Clinic Financial Oversight

• Ensure consistent revenue recognition and reporting practices across all entities
• Analyze clinic-level profitability with a focus on revenue cycle efficiency and margin optimization
• Identify operational and financial risks tied to billing inefficiencies or payer variability

Compliance, Risk & Controls

• Ensure compliance with healthcare billing regulations (e.g., payer requirements, coding compliance)
• Maintain audit-ready financials and documentation at all times
• Implement fraud prevention, billing compliance checks, and risk mitigation protocols
• Oversee multi-entity tax strategy and regulatory filings

Cash Flow & Working Capital

• Drive improvements in cash flow through optimized collections and reduced A/R cycles
• Forecast cash with revenue cycle visibility and payer timing considerations
• Align capital planning with revenue predictability and reimbursement trends

Qualifications

• Active CPA license
• 7+ years of progressive accounting/finance experience with significant ownership of financial reporting and close processes
• Deep expertise in healthcare revenue cycle management (required)
• Experience in multi-site medical practice or healthcare services environment strongly preferred
• Proven ability to improve collections, reduce A/R days, and optimize payer performance
• Strong knowledge of:
  • GAAP and technical accounting
  • Healthcare billing workflows and compliance
  • Internal controls and audit readiness
• Experience working with practice management systems, billing platforms, and ERP systems

Core Competencies

• CPA-level technical excellence and financial rigor
• Revenue cycle mastery with a data-driven mindset
• Ability to translate revenue cycle data into actionable operational improvements
• Strong partnership with clinical and operational leadership
• High accountability and ability to scale systems in a growth environment

 Benefits: 

• Performance-based bonus opportunity 

• Growth Opportunity: Promotion to CFO from this role is possible. 

• Health benefits 

• 401k retirement plan with company match 

• Paid time off, including vacation, floating holidays, and sick leave 

• Equity participation included  
• Promotion to CFO and commensurate raises possible 

Compensation

The annual salary range for this position is $180,000-200,000/year. The actual compensation for this role will be determined by a variety of factors, including but not limited to the candidate’s skills, education, and experience.

Position Summary

The Director/Senior Director of Global Regulatory Affairs (GRA) will report to the Senior Vice President of Regulatory Affairs and serve as a key leader in shaping and executing global regulatory strategies. This role will partner closely with the GRA team and cross-functional stakeholders to ensure compliance with international regulatory requirements and alignment with company objectives. The candidates major responsibilities will include the following:

• Regulatory Strategy & Advice: Develop and execute integrated regulatory strategies that optimize approval pathways for drug and device across all regions where clinical studies are conducted. Provide expert guidance on global regulatory requirements, life cycle management and evolving policies where RM is pursuing development and commercialization.

• Submission Oversight: Lead cross-functional teams to prepare high-quality regulatory submissions. Review and ensure consistency of regulatory documents with company strategy and health authority standards; manage submission strategies for all Rakuten Medical projects from early-stage (IND/CTA) through NDA/BLA and lifecycle management. Oversee planning and execution of global regulatory authority meetings, including briefing packages, strategy, positioning, and negotiations.
• Documentation & Compliance: Ensure compliance with all applicable global laws, regulations, and standards (eg FDA CFR, EMA guidelines, ICH, PMDA standards, EU MDR/IVDR, GCC regulations). Maintain regulatory filing and archiving systems; ensure documentation meets health authority requirements and guidance.
• Project Management: Develop regulatory project plans and timelines; coordinate submission team and regulatory department meetings; track goals, action items, and submission progress. Manage various regulatory vendors and contractors toward budget- and time-efficient completion of corporate goals. Proven ability to apply strong influence skills in leading cross-functional regulatory submission teams.
• Cross-Functional Collaboration: Work closely with teams in CMC, nonclinical, clinical development, medical writing, safety/PV, quality assurance, medical affairs, and program management to support timely and compliant submissions. Assess regulatory risk and drive mitigation strategies to support business continuity.
• Global Tracking: Monitor regulatory commitments, deliverables, and submission content across regions.

This position spans all functional areas requiring regulatory input, including early research, CMC, device, nonclinical, clinical development and commercial. The ideal candidate will bring strong leadership, strategic thinking, and deep knowledge of global regulatory frameworks to drive successful outcomes.

Key Duties and Responsibilities 

• Develop and execute integrated global regulatory strategies for drug and device programs across all regions as required.
• Maintain a thorough understanding of current and emerging global and regional regulations, guidance documents, and ICH standards for all application types and procedures, in all regions where the organization seeks to develop and commercialize products.
• Stay informed on regulatory requirements for biologics and combination products across all regions.
• Develop and manage submission strategies for all Rakuten Medical projects and planned submissions. Ensure regulatory documents are scientifically sound, consistent, and aligned with company strategy and health authority expectations.
• Coordinate and oversee the planning, preparation, and delivery of regulatory submissions throughout the product lifecycle—from preclinical and IND/CTA through clinical development, NDA/BLA, and ongoing lifecycle management.
• Serve as the primary interface with publishing and other regulatory vendors; review submissions for completeness and compliance with regulatory guidance and health authority expectations.
• Lead implementation of new regulatory systems and develop associated processes and SOPs.
• Manage regulatory project tracking tools to monitor deliverables, commitments, submission content, amendment and approval dates, and provide proactive status updates for all regions.
• Act as the primary regulatory lead on assigned project teams, providing strategic input and regulatory support.
• Ensure timely storage and archiving of regulatory documentation in a manner that facilitates efficient retrieval.
• Conduct regulatory review of external-facing materials (e.g., manuscripts, posters) as appropriate.
• Review clinical, CMC, and safety documentation to ensure regulatory compliance and completeness during authoring and finalization.
• Coordinate safety reporting and collaborate with Safety/Pharmacovigilance to ensure systems are in place for efficient tracking and reporting of safety information.
• Assist with onboarding new employees and manage consultants and related contracts as needed.
• Contribute to continuous improvement of operational processes for regulatory submissions and document trackin. 

Qualifications:

• Education:
  • Advanced degree in Life Sciences, Pharmacy, Regulatory Affairs, or related discipline (M.S., Ph.D., or Pharm.D.).

• Experience:

• • 10+ years of regulatory affairs experience in the biopharmaceutical industry, with at least 5 years in a leadership role.
  • Proven track record of managing global regulatory submissions (IND/CTA, NDA/BLA, MAA) and lifecycle management.
  • Experience in oncology or biologics preferred; combination product/device experience is a plus.

• Knowledge:

• • Deep understanding of global regulatory frameworks (FDA, EMA, PMDA, and other major health authorities).
  • Familiarity with ICH guidelines, GCP, and evolving regulatory trends.

• Technical Skills:

• • Expertise in regulatory strategy development and execution.
  • Strong document review and submission planning skills.
  • Proficiency with regulatory information management systems and electronic submission platforms (eCTD).

Key Competencies:

• Strategic Thinking: Ability to anticipate regulatory challenges and develop proactive solutions aligned with business objectives.
• Leadership & Collaboration: Skilled at leading cross-functional teams and influencing stakeholders across global regions.
• Communication: Exceptional written and verbal communication skills for health authority interactions and internal alignment.
• Project Management: Strong organizational skills with the ability to manage multiple priorities and meet tight deadlines.
• Problem-Solving: Analytical mindset to resolve complex regulatory issues and adapt to changing requirements.
• Integrity & Compliance: Commitment to ethical standards and regulatory compliance in all activities.

We are proud to offer a competitive compensation plan with an excellent benefits package including flexible time off, stock options, 401k, medical, dental, vision plans and more.

Rakuten Medical Inc. is proud to be an Equal Opportunity Employer. We celebrate diversity and are committed to building a team that represents a variety of backgrounds, perspectives and skills.

The expected salary range for this position based in California is $150,000 to $190,000 annually. Actual pay will be determined based on experience, qualification, geographic location, and other job-related factors.

What You Will Contribute To Altos

As part of our team, you will help to accelerate and optimize our progress in agentic AI methods for biological and clinical data curation and analysis.

In this role, you will be an integral part of our multidisciplinary teams building the computational platforms that will enable Altos to achieve its mission. You will collaborate with biomedical research experts as well as other machine learning scientists and engineers across the Institute of Computation to contribute to the Altos research and translation ecosystem, focusing on designing and building state-of-the-art agentic AI systems and workflows that tackle biological questions, accelerate clinical data analysis, and aid in the discovery of novel interventions for aging and disease.

The successful candidate will combine deep expertise in agentic AI methods with a strong foundation in bioinformatics and/or clinical R&D. You will work closely with domain experts to translate complex biological and clinical data challenges into intelligent, automated solutions. You will thrive in a fast-paced environment that stresses teamwork, transparency, scientific excellence, originality, and integrity.

Responsibilities

• Design and develop agentic AI workflows for biological and clinical data curation tasks
• Research and implement advanced context engineering techniques (RAG, agentic RAG, graph RAG) tailored to biomedical data
• Develop and optimize prompts and agent architectures for reliability, accuracy, and scientific rigor
• Build LLM-based tool-use systems and integrations relevant to bioinformatics and clinical R&D pipelines
• Collaborate with bioinformatics scientists, clinical researchers, and domain experts to identify automation opportunities and translate them into agentic solutions
• Evaluate and benchmark agentic systems, establishing rigorous metrics for performance and correctness in scientific contexts
• Stay current with the rapidly evolving landscape of agentic AI methods and contribute to internal best practices

Who You Are 

• Proven track record leveraging machine learning and AI to solve real-world problems
• Expertise in agentic AI methods development, including prompt optimization, LLM-based tool use, context engineering (RAG, agentic RAG, graph RAG), and agent evaluation
• Experience writing production-quality code with agentic frameworks (e.g., LangGraph, Pydantic-AI, DSPy, or similar)
• Deep familiarity with bioinformatics and/or clinical R&D, with the ability to engage meaningfully with domain experts on biological and clinical questions
• Proficiency with AI-assisted development tools (e.g., Claude Code, Cursor) to iterate rapidly
• A team player who thrives in collaborative environments and is committed to enabling colleagues to reach their full potential through giving and requesting feedback focused on professional growth
• Able to advise others across the wider function / company on cutting edge agentic AI practices and approaches to enable the science / research. Desire to constantly expand your skillset and knowledge. Keen to learn more about biology, machine learning, and medicine
• Inspired by the Altos mission of restoring cell health and resilience to reverse disease, injury, and age-related disabilities

Minimum Qualifications

• PhD in Computer Science, Machine Learning, Bioinformatics, or a related field
• Demonstrated experience developing agentic AI systems, including LLM-based tool use, prompt engineering, and context engineering techniques
• Strong foundation in machine learning principles and their application to real-world problems
• Strong background in bioinformatics, computational biology, or clinical R&D
• Familiarity with MCP server development and agent skill creation
• Very strong programming skills in Python, with experience writing production-quality, well-documented code
• Strong track record of published peer-reviewed research in AI/ML and/or computational biology

Preferred Qualifications

• Experience with AWS services (S3, Bedrock, Lambda) in the context of AI/ML workflows
• Experience with clinical trial data, regulatory data curation, or biomedical ontologies (e.g., CDISC, SNOMED, MedDRA)
• Track record working with NGS data (e.g., RNA-seq, ATAC-seq, DNA methylation) or other biological data modalities
• Experience designing evaluation frameworks and benchmarks for agentic AI systems
• Familiarity with knowledge graph construction and graph-based retrieval methods

The salary range for Redwood City:

• Senior Scientist I, Machine Learning: $257,400 - $330,000

The salary range for San Diego:

• Senior Scientist I, Machine Learning: $239,500 - $307,000

Exact compensation may vary based on skills, experience, and location.

#LI-NN1

For UK applicants, before submitting your application:

- Please click here to read the Altos Labs EU and UK Applicant Privacy Notice (bit.ly/eu_uk_privacy_notice)
- This Privacy Notice is not a contract, express or implied and it does not set terms or conditions of employment.

ESSENTIAL JOB FUNCTIONS:

Join us as we embark on an exciting journey in transforming the treatment landscape of acute myeloid leukemia (AML). We are seeking a dynamic and experienced Associate Director / Director, Marketing Promotions to play a critical role in the development, approval, and execution of core promotional materials supporting KOMZIFTI (ziftomenib) in relapsed / refractory (R/R) NPM1-m AML.

Reporting to the Senior Director of Brand Strategy and Marketing, this role will lead the end-to-end execution of promotional tactics, including MLR submission and approval, sales force rollout, and digital marketing execution, while supporting broader brand strategy. The successful candidate will bring strong experience partnering with field teams, managing agencies, and working cross-functionally in a highly regulated oncology environment.

Responsibilities

Strategic Planning & Brand Management

• Lead development and execution of annual tactical plans in alignment with brand strategy. 
• Distill market research findings and sales trends into insights that direct promotional efforts.

Promotional Development & Execution

• Lead the development of core promotional materials, including print, digital, and field-facing assets, from concept through MLR review, approval, and final production for HCP and patient audiences.
• Own and manage the MLR process, ensuring compliant, high-quality materials are delivered on time.
• Drive effective rollout of approved promotional tactics to sales teams, in close collaboration with Sales, Sales Training, and Commercial Operations
• Ensure promotional materials effectively translate brand strategy into clear, actionable field tools.

Digital & Omnichannel Execution

• Lead execution of digital marketing tactics, including email, web, virtual engagement tools, and non-personal promotion.
• Manage media agency to optimize channel mix, implement tactics, measure performance, and optimize future tactics accordingly across HCP and patient audiences.
• Ensure digital tactics align with brand strategy and compliance requirements

Sales Force & Field Engagement

• Serve as a key marketing partner to the field organization, incorporating field insights into promotional development.
• Demonstrate proven experience translating brand strategy to field teams at sales meetings and field training initiatives.
• Act as a trusted point of contact for sales leadership, ensuring alignment between marketing execution and field needs.

Performance & Budget Management

• In collaboration with insights team, establish, integrate and track KPIs, performance metrics, and ROI for marketing activities.
• Monitor product performance and propose promotional adjustments based on market dynamics.
• Prepare and deliver clear, concise presentations to senior leadership, including updates on promotional plans, execution status, and performance insight
• Manage promotional budget.

Job Specifications:

• Bachelor’s degree in relevant field, advanced degree preferred.
• Minimum of 7 years of experience in biotech or pharmaceutical marketing, preferably in oncology or hematology
• Demonstrated experience leading promotional material development and MLR review
• Proven track record of working directly with sales and field teams
• Strong experience managing external agencies (creative, digital, production)
• Experience executing digital and omnichannel marketing tactics in a regulated environment
• Ability to work effectively in a highly cross-functional organization
• Strong communication and interpersonal skills, with comfort presenting to senior leadership
• Highly organized, detail-oriented, and able to manage multiple priorities
• Ability to travel up to 20% (domestic with limited international)
• Sales experience is a plus
• Product launch experience preferred
• Strong analytical skills; comfortable navigating complex and ambiguous environments
• Alliance partnership experience beneficial

The base range for this role at an Associate Director level is $180,000 - $215,000 and Director level would be $223,000 - $258,000 per year. Individual pay may vary based on additional factors, including, and without limitation, job-related skills, experience, work location, and relevant education or training. Kura's compensation package also includes generous benefits, equity, and participation in an annual target bonus.

#LI-RM1

Position Summary

This position plays a critical role in strengthening and accelerating the global medical and scientific impact of Rakuten Medical’s Alluminox platform. Key responsibilities include designing and delivering training programs to external Health Care Professionals and internal teams in clinical development, operation and medical affairs/science functions. This role ensures that Alluminox technology is delivered to patient at the highest standard while gathering frontline feedback from medical society to enhance Rakuten Medical’s research, development and commercialization efforts.

Key Duties and Responsibilities 

• Design, organize, lead and execute training sessions for care professionals on product knowledge effectively
• Ensure patients globally in both clinical trial and commercial settings are treated at the highest standards and if necessary to provide onsite support
• Plan, organize, and execute Investigator Meetings, Advisory Board Meetings and other equivalent events and present on behalf of the company as needed
• Support research, development and commercialization efforts through collecting and synthesizing observation in the medical field and clinicians’ feedback
• Develop robust partnership relationship with HCPs within current and future therapeutic area
• Educating employees the insights and information gained from academic papers and conference
• Identify challenges for the mid to long-term global R&D and medical communication and propose/execute solutions from medical perspective.

Desired Education, Skills and Experience

• M.D. degree and surgeon experience required
• Specialty in otorhinolaryngology, gynecology or hepatology is a plus
• 10-year + Medical affair and / or R&D related experiences in healthcare industry required
• Demonstrated hands-on characteristics and proactiveness
• Focused on actions, problem-solving and result oriented
• Ability to establish strong partnership rapport with key internal and external stakeholders
• Capability to effectively collaborate with cross-functional team and communicate with leadership team
• Solid knowledge of the healthcare landscape such as hospital systems, various points of care, and the roles of relevant HCPs in the target Tas and the drug development process
• Exceptional self-management ability and able to self-motivate
• Strong understanding of compliance, and the legal and regulatory landscape as they relate to HCP interactions
• Fluent in Medical English listening, speaking, writing and reading is a must, other second language is a plus
• May require travel up to 50%

We are proud to offer a competitive compensation plan with an excellent benefits package including flexible time off, stock options, 401k, medical, dental, vision plans and more.

Rakuten Medical Inc. is proud to be an Equal Opportunity Employer. We celebrate diversity and are committed to building a team that represents a variety of backgrounds, perspectives and skills.

The expected salary range for this position based in California is $180,000 to $220,000 annually. Actual pay will be determined based on experience, qualification, geographic location, and other job-related factors.

Position Summary:  

The Clinical Pharmacology Lead is responsible for providing clinical pharmacology expertise to the cross functional product development team and contributing to clinical development through advancing MIDD (Model Informed Drug Development) initiatives. The core job responsibilities include analysis, interpretation and reporting of clinical PK and PK/PD data, preparation and review clinical pharmacology data for regulatory submissions. In addition to the Clinical Pharmacology Lead responsibilities, this position also serves as DMPK Lead through collaboration with research team on non-clinical DMPK, and translational pharmacology activities. 

Essential Duties and Responsibilities:

• Provide clinical pharmacology expertise to the cross functional product development team.
• Conduct data analyses including non-compartmental PK analyses, pop PK, and ER analyses.
• Design and execute clinical pharmacology studies (eg, food effect, DDI, AME/Mass Balance studies).
• Co-author regulatory documents such as protocol, study report, healthy authority briefing book, and IB.
• Collaborate with research team on non-clinical DMPK and translational pharmacology activities.
• Manage external CROs to ensure compliance with planned study protocols, deliverables, internal quality control standards, and timelines.
• Perform all duties in keeping with the Company’s core values, policies and all applicable regulations.

Required Education and Experience:

• PhD or PharmD with training in relevant fields such as pharmaceutical sciences, clinical pharmacology, and/or engineering. No prior industrial working experience is required for the Manager level position; a minimum of 7 years of relevant working experience is required for the Director level position.
• Solid knowledge and experience in pharmacokinetics, pharmacodynamics, and drug metabolism.
• Proficient in using WinNonlin, NONMEM, R, and other modeling and simulation software.
• Working experience in preclinical and clinical development of investigational drugs in diverse platforms including small molecules and biologics.
• Proven track record in authoring DMPK and Clinical Pharmacology components of regulatory documents.
• Excellent collaboration, communication, and interpersonal skills.
• Must be a highly flexible, results oriented, independent self-starter who enjoys working in a fast-paced and dynamic, team-oriented environment.

The anticipated salary range for this position is $190,000 to $245,000. The final salary offered to a successful candidate will be dependent on several factors that may include but are not limited to the type and length of experience within the job, type and length of experience within the industry, education, etcetera. In addition to base salary, the hired applicant will be eligible to receive an annual bonus and an equity grant at hire and annually in the form of the option to purchase stock in the future for a specified price.

At Element Biosciences, we are passionate about our mission to empower the scientific community with more freedom and flexibility to accelerate our collective impact on humanity. We have built a highly efficient product-driven organization where employees can learn, grow, and thrive in a challenging but encouraging environment. We are committed to scientific integrity, collegiality, honesty, objectivity, and openness.

We are seeking a Scientist, Histology to join our R&D team supporting the development of a next-generation multi-omics product for tissue samples, including formalin-fixed paraffin-embedded (FFPE) and fresh frozen (FF)specimens. In this role, you will lead and execute tissue preparation workflows and contribute to the development and optimization of protocols that enable robust downstream molecular and imaging assays. 

The ideal candidate brings strong expertise in histology and tissue processing along with experience working in cross-functional R&D environments. This role will play a key part in enabling the development of innovative spatial and multi-omic technologies. This role will report to the VP, Biochemistry and will be a role at our San Diego headquarters.

If you possess the following and want to make a meaningful impact, we invite you to explore this role.

Essential Functions and Responsibilities:

• Lead the preparation and processing of tissue specimens, including FFPE and fresh frozen tissues, for assay development and research applications
• Design, develop, and optimize histology workflows to support multi-omics and spatial biology assays specific to Element’s platform
• Perform tissue fixation, embedding, microtomy, cryosectioning, and slide preparation to generate high-quality tissue sections
• Develop and execute routine and advanced staining protocols, including H&E, immunohistochemistry (IHC), and immunofluorescence (IF)
• Evaluate tissue morphology and section quality, identify artifacts, and troubleshoot issues related to fixation, processing, and sectioning
• Establish quality control assays for tissue sections and blocks
• Collaborate with molecular biology, assay development, imaging, and bioinformatics teams to integrate tissue workflows into broader product development efforts
• Design and execute experiments to evaluate new reagents, tissue preparation protocols, and assay formats
• Establish and maintain standard operating procedures (SOPs) for histology and tissue handling workflows
• Operate and maintain histology instrumentation including microtomes, cryostats, automated tissue processors, and staining systems
• Analyze and communicate experimental results and present findings to cross-functional teams
• Mentor and provide technical guidance to research associates and junior scientists
• Support quality control and reproducibility efforts for tissue-based assays in product development

Education and Experience:

• PhD is preference OR MS with 4–6 years of relevant hands-on histology experience, OR BS with 5–7 years of relevant hands-on histology experience, preferably in a biotechnology, research, or clinical laboratory environment
• Strong expertise in: FFPE tissue processing and embedding; Fresh frozen tissue handling and cryosectioning; Microtomy and cryostat operation
• Experience performing routine histological staining (e.g., H&E) and immunostaining techniques with interpretation
• Demonstrated ability to produce high-quality, reproducible tissue sections suitable for microscopy and molecular assays
• Experience in preparation and quality control and integrity assessment of tissue samples for wide range of downstream workflows and assays
• Strong understanding of tissue morphology and common histological artifacts
• Experience troubleshooting histology workflows and optimizing protocols
• Strong documentation and communication skills
• Ability to work effectively in a fast-paced, multidisciplinary R&D environment
• HT or HTL certification (ASCP)
• Experience with multiplex immunofluorescence or spatial biology assays
• Familiarity with in situ hybridization techniques (e.g., RNAscope)
• Experience with spatial, single cell and bulk RNAseq and protein assays on tissue samples
• Experience with automated staining platforms (e.g., Leica, Ventana, Sakura)
• Experience working with human clinical tissue samples
• Prior experience contributing to biotech product or assay development
• Experience supporting spatial transcriptomics, proteomics, or other tissue-based multi-omics workflows

Physical Requirements:

• Frequently moves boxes weighing up to 20 pounds
• The position requires physical activity and the handling of chemicals; Candidates are required to follow the safety protocols and be familiar with personal protective equipment (PPE) while working in the laboratory environment

Location:

• San Diego - Headquarters

Travel: 

• Up to 10%

Job Type:

• Full-time/Exempt

Base Compensation Pay Range:

• $116,000 - $152,000

In addition to base compensation noted above, you will be eligible for stock options, discretionary annual bonus, no cost health insurance plans, 401k with company match, and flexible paid time off. 

Please note: Base compensation will depend on multiple factors, including geographic location, qualifications, and experience. 

We foster an environment such that all people are afforded the freedom to pursue their passions without regard to race, color, religion, national or ethnic origin, gender (including pregnancy), sexual orientation, gender identity or expression, age, disability, veteran status or any other characteristics protected by law.

Treeline Biosciences, a clinical-stage biotechnology company advancing precision medicines, is seeking an experienced small molecule process chemist to drive the development, scale-up, and commercial readiness of our small molecule, clinical-stage portfolio. This role centers around close collaboration with the medicinal chemistry team within the discovery portfolio. Additionally, the role is critical to ensuring clinical supply and commercial readiness for identified programs and ensuring that drug substance manufacturing processes meet quality, regulatory, safety, scalability, and scalability expectations. 

About the Position

Senior Scientist / Principal Scientist – Process Chemistry (Discovery Process Research)

Position Overview

We are seeking an experienced synthetic chemist to join our Process Chemistry (Discovery Process Research) team supporting drug discovery programs. This role focuses on route invention, reaction development, and scalable synthesis of key intermediates and drug candidates.

The scientist will lead from the bench within our project-based research and development organization, designing and executing synthetic strategies that enable discovery programs. The successful candidate will collaborate with cross-functional teams, including Medicinal Chemistry, DMPK, Toxicology, Drug Product, and Analytical Sciences to develop practical routes that support SAR exploration and deliver material for biological and early toxicology studies. The role emphasizes modern synthetic methodologies, efficient route design, and early scalability assessment.

Scientific Impact

• Enable drug discovery through innovative synthetic strategy. Develop creative and efficient routes that accelerate SAR exploration, enable rapid evaluation of new chemical matter, and deliver material for early toxicology studies.
• Solve complex synthetic challenges. Apply modern synthetic methodologies to access structurally complex molecules and support emerging therapeutic modalities.
• Translate discovery chemistry into scalable processes. Design practical routes that support both rapid compound synthesis and early-stage scale-up.
• Advance cross-disciplinary drug discovery. Partner closely with discovery scientists to translate synthetic innovation into therapeutic progress.

Responsibilities

• Collaborate with medicinal chemistry partners to support candidate selection and developability assessments.  Advise and assist with sourcing scaffolds and intermediates as appropriate. 
• Design and execute route scouting and synthetic strategies for drug candidates and key intermediates.
• Design and optimize chemical transformations and scalable synthetic routes to enable efficient and robust processes for discovery and early development programs.
• Enable rapid compound synthesis and methodologies to support SAR campaigns and discovery timelines.
• Apply modern synthetic technologies to address complex synthetic challenges.
• Support multi-gram to kilogram-scale synthesis for biological and toxicology studies.
• Manage external partners and cultivate strong, collaborative relationships to support program objectives.
• Contribute to early CMC understanding, including impurity identification and process considerations.
• Communicate results through technical reports, documentation, and presentations.
• May be involved with preparations for the first GMP synthesis of a clincial candidate for Phase 1 trials.
• Ability to travel up to 10% to support program needs, including on-site support at manufacturing plants and partner collaboration.

Qualifications

• Ph.D. in Organic Chemistry or related discipline with 3–8+ years of relevant industry or postdoctoral experience; M.S. with 6–10+ years of industry experience also considered.
• Strong expertise in synthetic organic chemistry, reaction development, and route design.
• Experience with complex molecule synthesis and route optimization.
• Familiarity with scale-up considerations and impurity control in chemical processes.
• Ability to work effectively within cross-functional discovery teams.
• Experience working with and managing external CDMO partners. 
• Strong written and verbal communication skills.
• Strong project leadership skills with the ability to manage complex timelines, multiple stakeholders, and evolving program priorities. 
• Strong communication and collaboration skills with a proven ability to work cross-functionally in a fast-paced, science-driven environment. 
• High level of personal integrity, commitment to excellence and to our patients 

Desired Experience

• Experience with modern synthetic methodologies and technologies (e.g., catalysis, flow chemistry, photochemistry, high-throughput experimentation, as well as other techniques).
• Experience enabling synthesis of structurally complex drug candidates or emerging modalities.
• Demonstrated creative problem solving in synthetic chemistry.

This position is classified as exempt. The anticipated annual base salary range for candidates who will work in San Diego is $166,380 to $189,533. The final base salary offered to the successful candidate will be dependent upon several factors that may include but are not limited to the type and length of experience within the job, and other factors. Treeline Biosciences is a multi-state employer, and this salary range may not reflect positions that work in other cities or states.

Recruitment fraud statement

Please be aware of recruitment fraud and related job scams, where scammers present themselves as recruiters but are seeking to steal money or personal information. Keep the following in mind to protect yourself:

• Treeline Biosciences will never ask for money from you as part of our recruitment process. Do not provide bank details or pay somebody for the promise of a job at Treeline.
• We do not conduct interviews through RingCentral, Skype or Telegram.
• Our job openings are first posted to treeline.bio/careers. If you locate a listing for a Treeline job on another site, please ensure it is also posted on our careers website.
• You can find more information about job scams at consumer.ftc.gov/articles/job-scams.
• To report job scams, head to ReportFraud.ftc.gov.

At Element Biosciences, we are passionate about our mission to empower the scientific community with more freedom and flexibility to accelerate our collective impact on humanity. We have built a highly efficient product-driven organization where employees can learn, grow, and thrive in a challenging but encouraging environment. We are committed to scientific integrity, collegiality, honesty, objectivity, and openness.

We are currently seeking a dynamic, highly motivated, and experienced individual for the position of Manager, Financial Planning & Analysis (FP&A), supporting our Commercial, R&D and Corporate teams. This role provides a unique opportunity to serve as a strategic financial partner for our Commercial, R&D and Corporate programs. The position will provide financial, operational, and strategic leadership in a matrix reporting environment with multiple stakeholders across different internal groups. Through insightful understanding of the life sciences business, the Manager, FP&A will be responsible for providing financial guidance on key business decisions, delivery of financial commitments and ensuring optimal deployment of capital.

The individual must have the ability to work independently and as an effective and engaged team member in a fast-paced environment. Strong initiative and follow-through are essential for this job. This role will report to Associate Director, Financial Planning & Analysis and will be a San Diego based role.

If you possess the following and want to make a meaningful impact, we invite you to explore this role.

Essential Functions and Responsibilities:

• Work closely with the Commercial, R&D and Corporate teams to provide business counsel and financial leadership to optimize strategic investments and cost efficiencies
• Develop accurate and timely monthly reports, quarterly financial forecasts, annual budgets, long-range plans, and expense tracking of assigned clinical programs and functional areas
• Provide detailed analysis, and proactively identify risks and opportunities to the forecast, and regularly communicate findings to the leadership team
• Deep understanding on standard financial processes such Purchase order (PO) management and invoice accruals/matching for budget management
• Work closely with the accounting team and ensure the complete, accurate and timely processing of the monthly close process
• Develop / maintain a strong partnership with the other internal groups and Finance colleagues to develop and share best practices
• Ensure integrity and accuracy of the financial statements and compliance with SMPA policies and procedures, maintain strong internal control environment
• Advise team and actively engage in investment decisions through understanding of the research and development strategies and cost drivers
• Basic understanding of Commercial and Corporate organizations to support successful investments and activities

Education and Experience:

• Bachelor’s degree in finance, or a related field of study with successful experience as finance business partner
• Minimum 8 - 12 (w/o Master's) or 6 - 8 years (with Master's) years of relevant experience in biotech or life sciences industry
• Experience should include budgeting, forecasting, planning and analysis for a global organization
• Strong cross-functional collaboration skills
• Ability to work within a team, sharing ideas for best practices and process improvements
• Ability to communicate technical or complex issues with clarity to non-financial individuals
• Must be proactive and possess the ability to work independently
• Ability to present results to multiple levels of the Corporate Strategy and Finance organizations in a clear and concise manner
• Strong problem-solving skills, especially related to financial system integration
• Experience using financial forecasting software such as NetSuite, DataRails, SAP, and Oracle
• Possess a basic understanding of valuation principals, to include discounted cash flow

Physical Requirements:

• Frequently moves boxes weighing up to 20 pounds

Location:

• San Diego (on-site)

Travel: 

• Up to 10% domestic travel

Job Type:

• Full-time/Exempt

Base Compensation Pay Range

• $119,000 - $156,000

In addition to base compensation noted above, you will be eligible for stock options, discretionary annual bonus, no cost health insurance plans, 401k with company match, and flexible paid time off. 

Please note: Base compensation will depend on multiple factors, including geographic location, qualifications, and experience. 

We foster an environment such that all people are afforded the freedom to pursue their passions without regard to race, color, religion, national or ethnic origin, gender (including pregnancy), sexual orientation, gender identity or expression, age, disability, veteran status or any other characteristics protected by law.

What You Will Contribute To Altos

An exciting opportunity is available to join Altos Labs. We are seeking highly motivated, creative, and collaborative individuals who are passionate and dedicated about using their expertise to make impactful contributions for unraveling the deep biology of cellular rejuvenation programming to restore cell health and resilience, including basic science, pre-clinical, and clinical-stage programs.

Responsibilities

• Engage in ground-breaking and innovative science.
• Support and manage internal/external collaborations in one or more multidisciplinary projects to accelerate essential research activities. 
• Study the mechanistic basis of cell programming for health and rejuvenation.
• Responsible for mentoring graduate students.
• Responsible for developing project-specific experimental strategies, techniques, and procedures.
• Responsible for helping PI train lab members, including scientists and technicians.
• Contribute to writing and dissemination of research results.
• Carry out research projects in collaboration with the PI.

Who You Are

We have multiple Scientist openings are are interested in having people at varying levels of experience. Minimum requirements for the Scientist role include:

• PhD and a documented record of professional achievement in the form of impactful publications.
• Excellent computer skills, including advanced proficiency with Google apps, Excel, and Powerpoint graphic skills to produce documents and manage office projects.
• Excellent professional writing skills and the ability to attune through writing and presentations to a variety of audiences including senior executives through entry-level employees.
• Problem-solving skills sufficient to identify issues, conduct research, and develop innovative solutions. 
• Ability to maintain cooperative working relationships with a broad range of people, including staff colleagues, lab members, faculty, outside agencies and collaborators, and the community. 
• Demonstrated high productivity and ability to complete work in a timely manner.
• Ability to organize work and set priorities.
• Ability to focus on details to produce accurate, quality work driven by deadlines.
• Ability to work in a dynamic environment and with others in a team.
• Strengths in dealing with ambiguity.

Preferred Qualifications

• Candidates with strong training in the following fields are preferred:
  
  
  • Epigenetics and Epigenetic modifications
  • Metabolism, including metabolome and adipose tissue/skeletal muscle/liver metabolism
  • Stem cell biology, prior experience with animal models is a plus
  • Single cell analysis of animal tissues
  • Screen platforms, including small molecules, CRISPR/Cas systems, RNAi, etc.
  • Gene delivery systems, including enhancing the delivery efficiency of AAVs
  • Tissues crosstalk
  • Animal disease models

The salary ranges for this position in San Diego, CA: 

• Scientist I $116,450 - $157,550
• Scientist II $137,000- $184,800
• Senior Scientist I $154,000 - $204,000
• Senior Scientist II $170,000- $247,000

Exact compensation may vary based on skills, experience, and location.

#LI-NN1

For UK applicants, before submitting your application:

- Please click here to read the Altos Labs EU and UK Applicant Privacy Notice (https://bit.ly/3fHGl98)
- This Privacy Notice is not a contract, express or implied and it does not set terms or conditions of employment

Position Summary

We are seeking a highly skilled and compassionate Allergist/Immunologist Physician to join our growing practice in Greater San Diego, Greater South Bay LA, & New Prospect Locations. As a key member of our healthcare team, you will be responsible for diagnosing and treating patients with a wide range of allergic and immunologic conditions. You will provide high-quality care, collaborate with other medical professionals, and have the opportunity to work in a patient-centered, multidisciplinary environment.

The ideal candidate must be a self-motivated and eager individual who will establish him/herself in a practice that enjoys continuous growth. Must have excellent communication skills, bedside manner, and a strong work ethic with a desire to be part of a team that is committed to caring for the whole patient. We place special emphasis on providing patient-centered care, quality outcomes and patient satisfaction. If you are a dedicated and caring Allergist/Immunologist with an interest in advancing the field through clinical research and looking to make a difference in the lives of patients, we encourage you to apply. This is a unique opportunity to shape the future of allergy and immunology care while contributing to groundbreaking research in a collaborative and supportive environment. This role is exempt (salary) and full-time, working 40 hours per week, Monday through Friday with minimal travel. 

Key Responsibilities

• Clinical Responsibilities
  • Diagnose, treat, and manage patients with allergies, asthma, immunologic conditions, and related diseases.
  • Conduct comprehensive patient evaluations, including medical history, physical exams, and appropriate diagnostic tests (e.g., skin tests, blood tests, pulmonary function tests).
  • Develop and implement individualized treatment plans, including medication management, immunotherapy, and lifestyle modifications.
  • Educate patients and their families about managing allergies, asthma, and immunologic conditions.
  • Perform procedures such as allergy skin testing, spirometry, and immunotherapy (allergy shots).
  • Oversee in-office oral food challenges, drug challenges, and immunotherapy treatments (oral immunotherapy and sublingual immunotherapy for environmental and food allergy)
  • Develop and implement individualized care plans based on patient needs and medical history, including:
  • Starting allergy immunotherapy for environmental allergies
  • Starting oral immunotherapy for food allergy
  • Recommending food or drug challenges as part of allergy evaluation
  • Collaborate with other specialists (e.g., pulmonologists, dermatologists, primary care physicians) to ensure comprehensive care for patients.
  • Maintain accurate and up-to-date medical records in compliance with healthcare regulations and confidentiality standards.
  • Stay informed about the latest advancements in allergy and immunology treatments and participate in continuing medical education (CME).
  • Ensure high patient satisfaction and provide empathetic care, focusing on patient education and wellness.
  • Additional duties as assigned. 
• Research Responsibilities
  • Engage in clinical research initiatives through Orso Health, Modena Health’s research arm, related to the diagnosis, treatment, and prevention of allergic and immunologic diseases, or other areas of clinical interest.
  • Participate in designing and conducting clinical trials, including trials on new therapies, biologic treatments, and immunotherapy options.
  • Analyze data, prepare research reports, and collaborate with research teams to publish findings in medical journals.
  • Contribute to the development of innovative clinical pathways and treatment strategies based on research findings.
  • Work closely with industry partners, academic institutions, and research foundations to advance clinical studies in allergy and immunology.
  • Provide mentorship and guidance to junior researchers interested in allergy and immunology research.
  • Present research findings at national and international conferences.
  • Additional duties as assigned.

Qualifications & Requirements

• Education
  • Doctor of Medicine (MD) or Doctor of Osteopathic Medicine (DO) degree from an accredited medical school.
• Experience
  • Completion of an accredited residency in Internal Medicine or Pediatrics.
  • Successful completion of a fellowship in Allergy and Immunology.
  • Board certified or board eligible in Allergy and Immunology.
  • 1–3 years of post-fellowship clinical experience preferred; will consider highly qualified new fellowship graduates.
  • Demonstrated experience in diagnosing and managing patients with allergies, asthma, and immunologic conditions.
  • Hands-on experience performing and interpreting allergy testing, spirometry, and administering immunotherapy
• Licensure & Certifications
  • Board certification or eligibility in Allergy and Immunology (ABAI).
  • Valid and unrestricted medical license to practice in California.
• Skills & Abilities
  • Strong knowledge of allergy, asthma, and immunologic diseases and treatments.
  • Interest and experience in clinical research, including trial design and data analysis.
  • Excellent communication and interpersonal skills, with the ability to build rapport with patients and their families.
  • Ability to work effectively both independently and as part of a collaborative healthcare team.
  • Compassionate and patient-centered approach to care.
• Preferred Qualifications
  • Experience in a clinical or private practice setting.
  • Bilingual in Spanish (preferred but not required).
  • Expertise in immunotherapy and biologic treatments for allergy and asthma.
  • Experience in writing research protocols, grant submissions, or publishing research.
  • Interest in exploring innovative treatments and contributing to the advancement of immunology.

Compensation

The annual salary range for this position in California is $130,000-250,000/year. The actual compensation for this role will be determined by a variety of factors, including but not limited to the candidate’s skills, education, and experience.

Position Summary

We are looking for a dedicated and compassionate Allergy and Asthma Nurse Practitioner/Physician Assistant to join our dynamic team. If you are passionate about patient care and have expertise in allergy and asthma management, we would love to hear from you.  As an Allergy and Asthma NP/PA, you will be responsible for providing direct patient care, performing assessments, diagnosing, and managing the treatment of patients with allergic conditions, such as allergic rhinitis, asthma, eczema, food allergy, amongst others. You will work collaboratively with our physicians, nurses, and support staff to provide comprehensive, high-quality care tailored to each patient's needs. 

The ideal candidate must be a self-motivated and eager individual who will establish him/herself in a practice that enjoys continuous growth. Must have excellent communication skills, bedside manner, and a strong work ethic with a desire to be part of a team that is committed to caring for the whole patient. This role is exempt (salary) and full-time, working 40 hours per week, Monday through Friday with minimal travel. 

The anticipated start date for this position is approximately 2–3 months from the date of the offer. Please note that the official start date is contingent upon completion of credentialing.

Key Responsibilities

• Patient Care
  • Evaluate patients with allergies, asthma, and related conditions through exams, history taking, and diagnostic testing (e.g., skin and lung function tests). 
  • Supervise and manage in-office procedures, including food and drug challenges, and immunotherapy treatments (oral and sublingual). 
  • Create personalized care plans, including starting allergy and food immunotherapy or recommending food/drug challenges. 
  • Prescribe medications and suggest lifestyle changes to manage symptoms. 
  • Educate patients and families on allergy and asthma care, medication use, and trigger avoidance. 
  • Track patient progress and update treatment plans as needed. 
  • Share responsibility for managing oral immunotherapy (OIT) patients, including rotating OIT call coverage. 
  • Treat in-office allergic reactions under physician supervision.
• Collaborative Care
  • Work closely with allergists, pulmonologists, and other healthcare professionals to ensure coordinated and effective patient care. 
  • Assist in performing office procedures such as allergy testing and desensitization therapies. 
  • Participate in multidisciplinary team meetings and contribute to patient care decisions. 
• Clinical Leadership
  • Provide mentorship and guidance to nursing and clinical staff. 
  • Stay up-to-date with the latest evidence-based practices in allergy and asthma management. 
  • Educate patients on new treatments and interventions, ensuring they are well-informed. 
• Administrative Duties
  • Maintain accurate and up-to-date patient records in compliance with healthcare regulations and practice protocols. 
  • Assist with the coordination of follow-up care and referrals to specialists when needed. 
  • Additional duties as assigned. 

Qualifications & Requirements

• Education
  • Master’s (MSN) or Doctorate (DNP) in Nursing from an accredited program. 
  • Certified as a Nurse Practitioner (NP) or Physician Assistant (PA) by ANCC or another recognized board. 
  • Must pass a national certification exam (e.g., ANCC’s Family Nurse Practitioner exam). 
• Experience
  • 0–3 years of NP/PA experience. 
  • Experience in allergy, asthma, respiratory care, or pulmonology preferred. 
  • Pediatric and adult care experience is a plus. 
• Licensure & Certifications
  • Active California NP or PA license. 
  • Active California RN license. 
  • DEA registration for prescribing medications. 
  • BLS certification (required); ACLS certification (preferred). 
  • Must complete certification with the California Board of Registered Nursing (BRN). 
• Skills & Abilities
  • Strong clinical assessment skills and the ability to diagnose and manage complex conditions. 
  • Ability to start IVs and knowledge of IV infusions 
  • Excellent communication and interpersonal skills, with the ability to educate and empower patients. 
  • Ability to work autonomously and as part of a collaborative team. 
  • High level of professionalism, confidentiality, and attention to detail. 
  • Proficiency with electronic health records (EHR) systems.

Compensation

The annual salary range for this position in California is $125,000-140,000/year. The actual compensation for this role will be determined by a variety of factors, including but not limited to the candidate’s skills, education, and experience.

Position Summary

We are seeking a highly skilled and compassionate Allergist/Immunologist Physician to join our growing practice in Greater San Diego, Greater South Bay LA, & New Prospect Locations. As a key member of our healthcare team, you will be responsible for diagnosing and treating patients with a wide range of allergic and immunologic conditions. You will provide high-quality care, collaborate with other medical professionals, and have the opportunity to work in a patient-centered, multidisciplinary environment.

The ideal candidate must be a self-motivated and eager individual who will establish him/herself in a practice that enjoys continuous growth. Must have excellent communication skills, bedside manner, and a strong work ethic with a desire to be part of a team that is committed to caring for the whole patient. We place special emphasis on providing patient-centered care, quality outcomes and patient satisfaction. If you are a dedicated and caring Allergist/Immunologist with an interest in advancing the field through clinical research and looking to make a difference in the lives of patients, we encourage you to apply. This is a unique opportunity to shape the future of allergy and immunology care while contributing to groundbreaking research in a collaborative and supportive environment. This role is exempt (salary) and full-time, working 40 hours per week, Monday through Friday with minimal travel. 

Key Responsibilities

• Clinical Responsibilities
  • Diagnose, treat, and manage patients with allergies, asthma, immunologic conditions, and related diseases.
  • Conduct comprehensive patient evaluations, including medical history, physical exams, and appropriate diagnostic tests (e.g., skin tests, blood tests, pulmonary function tests).
  • Develop and implement individualized treatment plans, including medication management, immunotherapy, and lifestyle modifications.
  • Educate patients and their families about managing allergies, asthma, and immunologic conditions.
  • Perform procedures such as allergy skin testing, spirometry, and immunotherapy (allergy shots).
  • Oversee in-office oral food challenges, drug challenges, and immunotherapy treatments (oral immunotherapy and sublingual immunotherapy for environmental and food allergy)
  • Develop and implement individualized care plans based on patient needs and medical history, including:
  • Starting allergy immunotherapy for environmental allergies
  • Starting oral immunotherapy for food allergy
  • Recommending food or drug challenges as part of allergy evaluation
  • Collaborate with other specialists (e.g., pulmonologists, dermatologists, primary care physicians) to ensure comprehensive care for patients.
  • Maintain accurate and up-to-date medical records in compliance with healthcare regulations and confidentiality standards.
  • Stay informed about the latest advancements in allergy and immunology treatments and participate in continuing medical education (CME).
  • Ensure high patient satisfaction and provide empathetic care, focusing on patient education and wellness.
  • Additional duties as assigned. 
• Research Responsibilities
  • Engage in clinical research initiatives through Orso Health, Modena Health’s research arm, related to the diagnosis, treatment, and prevention of allergic and immunologic diseases, or other areas of clinical interest.
  • Participate in designing and conducting clinical trials, including trials on new therapies, biologic treatments, and immunotherapy options.
  • Analyze data, prepare research reports, and collaborate with research teams to publish findings in medical journals.
  • Contribute to the development of innovative clinical pathways and treatment strategies based on research findings.
  • Work closely with industry partners, academic institutions, and research foundations to advance clinical studies in allergy and immunology.
  • Provide mentorship and guidance to junior researchers interested in allergy and immunology research.
  • Present research findings at national and international conferences.
  • Additional duties as assigned.

Qualifications & Requirements

• Education
  • Doctor of Medicine (MD) or Doctor of Osteopathic Medicine (DO) degree from an accredited medical school.
• Experience
  • Completion of an accredited residency in Internal Medicine or Pediatrics.
  • Successful completion of a fellowship in Allergy and Immunology.
  • Board certified or board eligible in Allergy and Immunology.
  • 1–3 years of post-fellowship clinical experience preferred; will consider highly qualified new fellowship graduates.
  • Demonstrated experience in diagnosing and managing patients with allergies, asthma, and immunologic conditions.
  • Hands-on experience performing and interpreting allergy testing, spirometry, and administering immunotherapy
• Licensure & Certifications
  • Board certification or eligibility in Allergy and Immunology (ABAI).
  • Valid and unrestricted medical license to practice in California.
• Skills & Abilities
  • Strong knowledge of allergy, asthma, and immunologic diseases and treatments.
  • Interest and experience in clinical research, including trial design and data analysis.
  • Excellent communication and interpersonal skills, with the ability to build rapport with patients and their families.
  • Ability to work effectively both independently and as part of a collaborative healthcare team.
  • Compassionate and patient-centered approach to care.
• Preferred Qualifications
  • Experience in a clinical or private practice setting.
  • Bilingual in Spanish (preferred but not required).
  • Expertise in immunotherapy and biologic treatments for allergy and asthma.
  • Experience in writing research protocols, grant submissions, or publishing research.
  • Interest in exploring innovative treatments and contributing to the advancement of immunology.

Compensation

The annual salary range for this position in California is $130,000-250,000/year. The actual compensation for this role will be determined by a variety of factors, including but not limited to the candidate’s skills, education, and experience.

Position Summary

We're looking for an experienced Licensed Vocational Nurse II (LVN) to join our growing allergy practice. The ideal candidate has a passion for clinical care, excellent communication skills, and thrives in a fast-paced environment focused on quality and patient satisfaction. As an LVN, you will provide support for a diverse number of tasks, including, but not limited to performing allergy and asthma testing, administering injections, educating patients, and creating allergy serums and oral desensitization vials for our food allergy program. This position reports to the Practice Manager and physicians onsite but will work closely with the team consisting of NPs, nurses, other LVNs, and MAs. This position is perfect for an LVN that wants to advance and make a real contribution to their community and team.

This is a full-time, non-exempt (hourly) position, scheduled for 40 hours per week. Work hours may vary based on assigned clinic location, Monday through Friday. This role will be based primarily in our La Jolla and Solana Beach clinics but may also provide support to other nearby locations within San Diego County. The ideal candidate is adaptable and enjoys collaborating across multiple sites to ensure seamless operations and excellent patient experiences.

Key Responsibilities

• Patient Care & Education
  • Educate patients and families on allergy and asthma management, including respiratory spacer use and anaphylaxis awareness.
  • Deliver high-quality clinical care and support throughout patient visits.
• Clinical Procedures & Testing
  • Perform vital signs, patient intake, skin prick, patch, and breathing tests under physician or RN supervision.
  • Administer allergy immunotherapy, nebulized, and respiratory medications per provider orders.
  • Assist with procedures such as spirometry and food/drug challenges.
  • Monitor patients during and after treatments, reporting concerns to clinical leads.
• Provider Support & Documentation
  • Prepare exam rooms and patients for provider visits; assist during procedures.
  • Send prescriptions, complete care plans, and discharge summaries.
  • Document vitals, test results, and patient data accurately in ModMed EMR.
  • Maintain clean, organized, and well-stocked clinical spaces.
  • Contribute to a collaborative, team-based care environment.
• Administrative & Operational Tasks
  • Submit prior authorizations as needed.
  • Stock and manage inventory for clinical areas, medications, and testing trays
  • Use sterile technique for serum preparation per ACAAI guidelines.
  • Support both front and back-office functions as needed.
• Training, Compliance & Professional Standards
  • Follow HIPAA and OSHA regulations.
  • Demonstrate clinical competence and adhere to nursing leadership directives.
  • Participate in onboarding and training of new team members, sharing Modena’s clinical standards.
• Other duties as assigned.

Qualifications & Requirements

• Education: Completion of a state-approved or accredited medical assisting, nursing, or healthcare program (e.g., diploma, associate’s degree, or equivalent).
• Experience:
• Minimum 2–3 years of experience in an outpatient clinical setting; allergy/immunology preferred.
• Experience with EMR systems; ModMed experience is a plus 
• Licensure & Certification:
• Active LVN license in the state of employment (California)
• CPR certification required (or willingness to obtain) 
• Current BLS (Basic Life Support) certification 
• Skills & Abilities:
• Able to perform complex tasks requiring independent judgment, prioritization and clinical knowledge
• Proficient in phlebotomy and pulmonary function testing
• Knowledgeable with patient education regarding medications and environmental controls 
• Detail-oriented with strong organizational skills
• Excellent verbal and written communication skills 
• Professional, compassionate, and committed to patient care 

Compensation

The hourly range for this position is $28.00-$40.00/hour. The actual compensation for this role will be determined by a variety of factors, including but not limited to the candidate’s skills, education, and experience.

We are looking for a Health Sensing Hardware Engineer to join our hardware team working on future wearables and accessory devices reporting directly to the Director, Hardware Sensing Technologies.  This opportunity will be hybrid out of our San Francisco or San Diego office.

What you will do: 

• Develop and validate physiological sensing systems for acquiring and analyzing physiological signals in wearable health and wellness products
• Define hardware and software technical specifications and implement test and calibration protocols both internally and at manufacturer sites
• Ensure that the physiological sensors integrated in our products meet their specifications from prototype to mass production
• Build and validate hardware architectures optimized for low-noise, high-resolution time-series signal collection
• Plan and execute benchtop and on-body testing to evaluate system performance across various user populations
• Support validation and compliance efforts in collaboration with regulatory, research, and clinical teams
• Work cross-functionally to ensure end-to-end system performance and signal integrity
• Conduct rigorous testing and troubleshooting to ensure sensor performance across varying environmental and use-case conditions
• Collaborate closely with mechanical and electrical engineers to integrate sensors within constrained form factors and flexible layouts
• Partner with firmware and software teams to enable and refine features built on physiological data
• Work directly with sensor vendors to evaluate new components, optimize performance, and address integration challenges
• Travel occasionally to Finland and to global manufacturing or development sites as required (15%–20%) 

Requirements:

We would love to have you on our team, if you have:

Technical Expertise 

• Strong electrical engineering background and experience with the design and testing of low-noise analog or mixed-signal systems
• Strong understanding of time-series physiological signal acquisition, including best practices for minimizing noise and motion artifacts
• Familiarity with algorithmic methods for time-series signal modeling and calculating physiological metrics
• Simulation and modeling experience using tools like ANSYS, CST, or COMSOL
• Skilled in embedded software and data acquisition tools such as C/C++, Python, or similar
• Experience with data analysis and signal processing tools such as Python, MATLAB, or JMP

Problem Solving and Analytical Thinking

• Strong experimental and analytical skills with a methodical approach to isolating and debugging complex issues across hardware and algorithm domains
• Ability to work independently through ambiguity and rapidly iterate on early-stage concepts
• Driven by data and eager to understand root causes behind performance issues

Communication and Collaboration

• Effective communicator across disciplines, with the ability to clearly convey technical insights both in written and verbal form to technical and non-technical audiences
• Experience working in cross-functional teams spanning hardware, firmware, product, and research
• Contributed to project documentation, planning, and alignment with stakeholders

Educational Background

• Bachelor’s degree in electrical engineering, mechanical engineering, biomedical engineering, physics,or related field with 7+ years of relevant industry experience
• Master’s degree with 5+ years, or PhD with 2+ years of relevant industry experience

Prototyping and Testing

• Hands-on experience building and characterizing early-stage hardware systems
• Proficiency using various lab instrumentation tools such as digital multimeters, oscilloscopes, signal generators, spectrum analyzers, physiological simulators, power analyzers, and environmental chambers

Bonus Points:

• Experience developing or integrating physiological sensing systems into wearable or health-oriented products
• Track record of supporting high volume products from early prototyping through manufacturing and launch
• Knowledge of regulatory or safety standards for health-related technologies
• Prior work in validation studies or performance benchmarking across diverse populations

Benefits 

At Oura, we care about you and your well-being. Everyone here at Oura has a ring of their own and we are continually looking to improve employee health and add to our benefits!

What we offer:

• Competitive salary and equity packages
• Health, dental, vision insurance, and mental health resources
• An Oura Ring of your own + employee discounts for friends & family
• Fertility benefits through Carrot Pro
• Flexible working hours and remote working arrangements
• $750 Learning & Development credit
• 20 days of PTO + 13 paid holidays + 8 days of flexible wellness time off
• 5 days paid sick leave, 5 days bereavement leave, 12 weeks paid parental leave
• Amazing culture of collaborative and passionate coworkers

Oura takes a market-based approach to pay, which may vary depending on your location. US locations are categorized into tiers based on a cost of labor index for that geographic area. While most offers will be closer to the starting range, successful candidates’ pay will be determined based on job-related skills, experience, qualifications, work location, internal peer equity, and market conditions. These ranges may be modified in the future.

• Region 1 Range (SF): $217,000 - $267,950
• Region 2 Range (SD): $197,000 - $243,800

A recruiter can determine your zones/tiers based on your US location.

To all recruitment agencies: Oura does not accept agency resumes. Please do not forward resumes to our jobs alias, Oura employees or any other organization location. Oura is not responsible for any fees related to unsolicited resumes.

Oura is proud to be an equal opportunity workplace. We celebrate diversity and are committed to creating an inclusive environment for all employees. Individuals seeking employment at Oura are considered without regards to age, ancestry, color, gender (including pregnancy, childbirth, or related medical conditions), gender identity or expression, genetic information, marital status, medical condition, mental or physical disability, national origin, protected family care or medical leave status, race, religion (including beliefs and practices or the absence thereof), sexual orientation, military or veteran status, or any other characteristic protected by federal, state, or local laws. We will not tolerate discrimination or harassment based on any of these characteristics.

Position Summary: 

Reporting to the CMO, the VP Global Pharmacovigilance has overall responsibility for drug safety activities for early and late phase assets, including furthering the development and implementation of the clinical development strategy. The VP will be accountable for overseeing safety and pharmacovigilance across development and expected global launches and, ultimately, post-marketed products. The VP must possess a strong knowledge of global pharmacovigilance regulations, operational efficiencies, information systems, and best industry practices to effectively solve challenges and facilitate PVG compliance.

Note this position can be hybrid in our San Diego or South San Francisco locations or fully remote anywhere in the United States.   

Essential Duties and Responsibilities:

• Provide Safety Science leadership for clinical development programs and program teams and integrate safety science strategy with clinical development.
• Represent GPV in communication with health and regulatory authorities.
• Represent GPV at independent Data Safety Monitoring Committee meetings.
• Provide medical oversight of the GPV function including medical review of all cases.
• Provide medical input for maintaining REMS, RMP safety monitoring commitments.
• In collaboration with other members of GPV, create and maintain a signal detection process for Erasca’s products with a clearly defined signal detection strategy for each asset.
• In collaboration with other members of GPV, ensure robust processes are implemented to meet REMS/RMP commitments.
• Overall responsibility for development and implementation of QPV, in collaboration with Quality and GPV Systems.
• Provide periodic benefit-risk assessment reports for internal use.
• Contribute to the preparation of, review, and approve aggregate safety reports required by health authorities.
• Serve as SME author, reviewer, and approver for drug-safety related regulatory reports and clinical study documents (including clinical study protocols, Informed Consent Forms, Investigator Brochures, Integrated Summary of Safety (ISS), Integrated Summary of Efficacy (ISE), product package labeling, Company Core Safety Information, etc).
• Work with external partners to jointly manage cases, safety reporting, and signal detection across global development for molecule candidates.
• Manage implementation and/or operation of data analytics and data reporting tools to support drug safety compliance and analysis.
• Build and lead highly functioning GPV team including Safety Operations and Safety Science, utilizing internal and external resources.
• Develop operating plans and budgets and allocate resources to ensure budgets, schedules, and performance requirements are met.
• Assess process, systems, and staffing needs to scale for multiple late-stage trials, including oversight of CROs and vendors.
• Develop and maintain relationships across Erasca, particularly in Clinical Development, Clinical Operations, Biometrics, and Regulatory Affairs.
• Perform all duties in keeping with the Company’s core values, policies, and all applicable regulations.

Required Education and Experience:

• Doctor of Medicine or x-US equivalent with industry experience in safety science for oncology clinical development required; PharmD or other relevant clinical degree may be considered.
• 12 or more years of experience in the biotechnology or pharmaceutical industry with knowledge of GCP, clinical trial conduct, data interpretation, and safety in clinical development. A mix of large and small company experience highly preferred.
• Excellent scientific and clinical and analytical knowledge base, with the ability to assess data and understand safety and medical implications.
• In-depth knowledge of clinical research, including FDA and international regulations, clinical study design, and documentation.
• Experience with early clinical development required; experience in late-stage clinical development and NDA or BLA submission preferred.
• Extensive experience interfacing with US (FDA) and x-US health authorities required. Experience executing clinical trials in China, reporting safety data to China health authorities preferred.
• In depth knowledge of Safety Science and Safety Operations disciplines, with exposure to both internally and externally managed safety systems and databases.
• Direct management experience with proven ability to effectively lead, coach, mentor, and manage others.
• Demonstrated ability to achieve high performance goals and meet deadlines in a fast-paced environment.
• Effective interpersonal, communication and influencing skills, including excellent writing skills; must be a collaborative team player with a can-do attitude and the ability to identify and implement creative solutions to complex technical problems.
• Strong learning orientation, curiosity, and commitment to science and patients.

The anticipated salary range for this position is $370,000 to $390,000. The final salary offered to a successful candidate will be dependent on several factors that may include but are not limited to the type and length of experience within the job, type and length of experience within the industry, education, etcetera. In addition to base salary, the hired applicant will be eligible to receive an annual bonus and an equity grant at hire and annually in the form of the option to purchase stock in the future for a specified price.