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Associate Director, IT Operations - Digital Solutions and Technology
About Us…
Obsidian Therapeutics is pioneering engineered cell and gene therapies to deliver transformative outcomes for patients. Obsidian’s programs apply our cytoDRiVE® technology in Cell and Gene therapy products to control expression of proteins for enhanced therapeutic efficacy and safety. Obsidian’s lead program is currently in clinical development for the treatment of patients with metastatic melanoma and non-small cell lung cancer.
We’re proud of our diverse talented team and committed to cultivating an environment of inclusion where each person feels a strong sense of belonging and is supported to continuously learn and contribute their best work. Our Research team is based in the heart of Cambridge, MA, and Technical Operations team is based in our purpose built facility in Bedford, MA. Obsidianites enjoy a highly collaborative culture, competitive salary and benefits, and potential for ownership through stock options.
Our Opportunity…
We are looking for a strategic and hands-on Associate Director, IT Operations to lead and optimize Digital Solutions & Technology operations at Obsidian, delivering secure, compliant, and scalable technology services that enable our clinical-stage biotech teams to achieve breakthrough scientific and business outcomes.
You Will...
- Develop and execute Digital Solutions & Technology operations strategy aligned with Obsidian’s growth, compliance needs, and culture.
- Lead day-to-day operations, including infrastructure, cloud environments, enterprise systems, and lab/scientific software.
- Manage MSP resources, ensuring high-quality support and service levels.
- Partner with Info Security lead to ensure robust cybersecurity and data protection.
- Optimize Digital Solutions & Technology processes (incident, problem, change management) and drive adoption of best practices, with a strong emphasis on ITIL and change management in a controlled, regulated environment.
- Manage vendor relationships and operations budget.
- Support onboarding/offboarding, access management, and end-user training.
- Foster a culture of accountability, collaboration, and continuous improvement.
- Risk Management & Business Continuity: Identify, assess, and mitigate IT risks; develop and maintain business continuity and disaster recovery plans.
- Work closely with Facilities, Lab Operations, and other business units to ensure Digital Solutions meet evolving scientific and operational needs.
- Continuous Improvement & Innovation: Drive process optimization and adoption of new technologies to improve service delivery and operational efficiency.
- KPIs & Metrics: Define, track, and report on IT operational KPIs (e.g., uptime, ticket resolution, user satisfaction, compliance metrics).
- Regulatory Audit Readiness: Prepare for and support regulatory audits (FDA, SOX, etc.), ensuring documentation and processes are audit-ready.
Key Systems & Platforms
- Networking: Cisco Meraki, Fortinet
- Scientific/Lab: Benchling, Egnyte
- HR: ADP, Greenhouse, Pave
- Finance: NetSuite, FloQast, Concur
- Business Development: DataSite DataRooms
- Enterprise: M365, Adobe, Teams, Teams Room Systems
- Ticketing: Freshdesk
- Compliance: ComplianceWire, validated SharePoint
You Bring...
Core Qualifications
- Bachelor's degree in computer science, Information Technology, or related field with 10+ years of relevant IT experience, including leadership of IT operations in a regulated environment (biotech, pharma, or healthcare preferred).
- Experience with IT operations in agile, fast-growing companies.
- Experience with GxP systems operational support (CSV/CSA).
- Experience with change control systems and processes for GxP/SOX.
- Experience managing MSPs and IT service delivery across multiple locations.
- Strong knowledge of enterprise platforms (NetSuite, M365, ADP, Benchling, etc.) and lab/scientific software.
- Experience managing Lab IT systems
- Excellent planning, coordination, and time management skills.
- Strong oral, written, and visual communication skills.
- Ability to build productive relationships across scientific, business, and technical teams.
- Systems thinking and sound judgment, especially in risk management and escalation
- Collaborative and accountable – recognizes success requires teamwork and interdisciplinary thinking; shares feedback and ideas to facilitate better outcomes
- Self-motivated, with a proven ability to meet objectives and timelines, managing multiple responsibilities in parallel.
- Flexible - adapts to change in a fast paced, rapidly developing environment
- Curious and humble – seeks and welcomes input/expertise of others, continuous learner
- Tenacious and resilient – is not easily overwhelmed by challenges, delivers on commitments
Obsidian is committed to equitable and transparent pay practices.
The anticipated base salary range for this role is below. The actual base salary offered will be determined based on a combination of factors, including applicable qualifications, level of education, the depth of experience, unique skills, geographic location, internal equity, and/or business needs. The actual base salary offered will be in accordance with federal, state, and/or local wage requirements for the role’s location.
Our competitive compensation package includes an annual incentive bonus as a percentage of actual base salary and long-term incentives in the form of employee stock options, both of which are commensurate with the role’s level. We also offer a generous benefits package which includes comprehensive medical, dental, and vision coverage; company contributions to health savings and retirement accounts; ample paid time off; access to wellness programs; and rich career growth opportunities.
Obsidian is proud to be an equal opportunity employer, cultivating a welcoming and diverse environment. All applicants will receive consideration for employment without regard to race, color, religion, gender, gender identity or expression, sexual orientation, national origin, genetics, disability, age, veteran status or any other applicable legally protected characteristics.
Ready to apply?
Apply to Obsidian Therapeutics
Principal Software Developer
Principal Software Developer, Cognito Therapeutics, Inc.
Location: Cambridge, MA, USA, Full-time
Company Description
Cognito Therapeutics, Inc. is a venture-backed (Morningside Ventures, FoundersX, IAG, Starbloom) late clinical stage company translating scientific findings from MIT into therapeutic approaches for brain health, including Alzheimer’s disease and other neurodegenerative conditions. We were awarded a Breakthrough designation by the FDA in December 2020 based upon our feasibility data that showed our therapy’s strong safety profile and a notable preservation of cognition and function in patients with mild-to-moderate Alzheimer’s. We completed enrollment in our pivotal study, HOPE, in June 2025 and expect to release topline data from the trial in summer 2026. We are a fast-moving, highly motivated team of innovators with the ambitious goal of helping millions of patients and caregivers around the world who are impacted by neurodegenerative conditions. With our patented brain stimulation technology, we are committed to developing convenient, safe and effective neuroprotective therapies to improve brain health and well-being for all.
About the Job
We are seeking a talented and motivated Principal Software Developer to join our dynamic and innovative team. As a Principal Software Developer, you will take the lead in designing, developing, and maintaining high-quality software solutions that meet our product and business needs. You will collaborate closely with cross-functional teams, including product managers, designers, and quality assurance professionals, to deliver exceptional software products that drive our business forward. You’ll take ownership of software projects in critical areas. As the company expands you will lead and guide peers and junior technical staff in your area(s) of expertise.
Roles & Responsibilities:
- Develop high-quality software solutions: Design, code, test, and debug software applications using programming languages and frameworks such as Java, C, C++, Python, or JavaScript, ensuring adherence to coding standards and best practices.
- Collaborate with cross-functional teams: Work closely with product managers, designers, and other stakeholders to understand requirements, provide technical insights, and contribute to the overall product vision.
- Lead through the full software development life cycle: Contribute to all phases of the software development process, including requirements gathering, design, implementation, testing, deployment, and maintenance.
- Perform code reviews and ensure software quality: Review code written by team members, provide constructive feedback, and conduct thorough testing to identify and fix bugs, ensuring software quality and reliability.
- Stay up-to-date with industry trends: Continuously learn and stay current with the latest tools, technologies, and programming languages relevant to software development, and propose innovative solutions to enhance our software products.
- Troubleshoot and resolve technical issues: Investigate and address software defects, performance bottlenecks, and other technical issues, collaborating with the team to find effective solutions.
- Collaborate in an Agile environment: Run Agile ceremonies, such as sprint planning, daily stand-ups, and retrospectives, fostering a collaborative and iterative approach to software development.
- Lead Projects: Manage small technical teams, and interface with peers and superiors to reach outcomes important to the company.
- Mentor Junior Staff: Provide technical and career guidance to more junior software staff, fostering an environment of collaboration, technical excellence and growth.
- Document and Communicate: Create and maintain technical documentation, including design specifications, user manuals, and API documentation, and effectively communicate complex technical concepts to both technical and non-technical stakeholders.
Who You Are
Join our team as a Principal Software Developer and contribute to the development of innovative software solutions that drive our organization's success. Together, we can make a meaningful impact and create exceptional software products that exceed our customers' expectations.
Minimal Qualifications
- Bachelor's degree in Computer Science, Software Engineering, or a related field. Equivalent work experience may be considered.
- 8+ years of Software Development experience
- Demonstrated experience leading complex technical projects or systems, with expertise in one or more programming languages and frameworks.
- Strong problem-solving skills and ability to analyze complex problems, propose creative solutions, and implement them effectively.
- Solid understanding of software development principles, practices, and methodologies, including Agile/Scrum.
- Familiarity with version control systems (e.g., Git), software testing, and debugging tools.
- Excellent teamwork and communication skills, with the ability to collaborate effectively with cross-functional teams and articulate technical concepts to non-technical stakeholders.
- Experience leading small technical teams, where you remain a highly engaged individual contributor.
- Strong attention to detail and a commitment to delivering high-quality software solutions. Strong technical opinions driven by experience and expertise.
- Continuous learning mindset and a passion for staying up-to-date with emerging technologies and industry trends.
- Software Development Life Cycle experience is a plus
- Medical Device Experience is a plus
- Programming with mobile applications is a plus
- Embedded device experience is a plus
- FDA Cybersecurity compliance experience is a plus
- Cloud application development is a plus
- Leading a team of software developers.
Ready to apply?
Apply to Cognito Therapeutics
We are seeking an experienced Embedded Software Engineer (Rust) to join our Platform team (folks looking after the spacecraft). The successful candidate will play a crucial role in developing software for our satellite systems, contributing to the expansion and enhancement of our space-based data collection capabilities.
Ideal candidates will embrace the commercialization of nanosatellite systems and adapt to low-cost, fast-paced systems design, development, and implementation methodologies that set Spire apart from our competition. In this fast-paced environment, the design to launch cycle is measured in weeks and months, not years!
What You’ll Do as a Spacecraft Embedded Software Engineer:
- Develop daemons in Rust that interface with embedded systems using low- level protocols
- Implement communication interfaces between embedded systems and higher-level processes
- Integrate C code for specific hardware interfaces
- Contribute to the design and implementation of fault-tolerant systems
- Collaborate closely with the Electrical Engineering team to ensure optimal software-hardware integration
- Create and maintain comprehensive documentation for APIs and system architectures
- Contribute to the continuous improvement of our development processes and tools
Key Skills:
- Proven experience in embedded systems development using Rust
- Knowledge of or adaptability to Linux-based development (Ubuntu)
- Proficiency in integrating C code with Rust projects
- Experience with real-time communication protocols
- Experience with inter-process communication protocols
- Understanding of electronics and ability to communicate effectively with hardware engineers
- Excellent documentation skills
Preferred Skills:
- Familiarity with safety-critical embedded systems in any industry
- Experience with Yocto for embedded systems
- Knowledge of version control systems, particularly Git and GitHub
- Familiarity with CI/CD pipelines
- Experience with project management tools
- Proficiency in scripting languages like Python and Bash
- Understanding of cybersecurity principles for embedded systems
- Knowledge of telemetry and command systems
- Experience with formal verification methods for critical software components
- Experience in implementing Fault Detection, Isolation, and Recovery (FDIR) systems for embedded applications
Tools and Technologies: Rust, C | Scripting languages (Bash/Python) | Ubuntu (development environment) | Yocto (target environment) | Version control using Git
Spire operates a hybrid work model, and this position will require you to work a minimum of three days per week in the office.
Access to US export-controlled software and/or technology may be required for this role. If needed, Spire will arrange the necessary licenses—this is not something candidates need to have before applying. #LI-RK1
The anticipated base salary range for this position is listed below. Final base salary for this role will be based on the location, skills, experience and qualifications. In addition to base compensation, this role may be eligible for annual equity awards and our employee benefits program, including vacation, sick, and personal time off; optional medical, dental, vision, life, and disability coverage; a 401(K) plan; health and wellness reimbursement program; and participation in Spire’s Employee Stock Purchase Plan.
Global Perks
🛰️ Name Your Satellite Program (NYSP)
🚀 Launch Attendance
🌴 Generous Time Off Policy
🎓 Education Assistance Program
🥰 Employee Assistance Program (EAP)
📈 Employee Stock Purchase Program (ESPP)
👣 Family Leave
💪 Fitness Reimbursement
🧡 Employee Referral Program
🍉 Healthy snacks & beverages in every office
About Spire
We improve life on Earth with data from space.
Spire Global is a space-to-cloud analytics company that owns and operates the largest multi-purpose constellation of satellites. Its proprietary data and algorithms provide the most advanced maritime, aviation, and weather tracking in the world. In addition to its constellation, Spire’s data infrastructure includes a global ground station network and 24/7 operations that provide real-time global coverage of every point on Earth.
Spire is Global and our success draws upon the diverse viewpoints, skills and experiences of our employees. We are proud to be an equal opportunity employer and are committed to equal employment opportunity regardless of race, color, ancestry, religion, sex, national origin, sexual orientation, age, marital status, disability, gender identity or veteran status.
To help maintain a safe and secure workplace for Spire employees, all candidates who receive a conditional offer will be required to complete a background check. This may include criminal history and employment verification.
Please take a moment to review Spire's Global Data Privacy Notice for Employees, Contractors, Candidates and Visitors, as well as Spire's Privacy Policy.
Kindly be advised that communication regarding your application may come from @spire.com, @recruiting.spire.com, or from Candidate.fyi (our scheduling tool).
Ready to apply?
Apply to Spire
We are seeking an experienced Embedded Software Engineer (Rust) to join our Platform team (folks looking after the spacecraft). The successful candidate will play a crucial role in developing software for our satellite systems, contributing to the expansion and enhancement of our space-based data collection capabilities.
Ideal candidates will embrace the commercialization of nanosatellite systems and adapt to low-cost, fast-paced systems design, development, and implementation methodologies that set Spire apart from our competition. In this fast-paced environment, the design to launch cycle is measured in weeks and months, not years!
What You’ll Do as a Spacecraft Embedded Software Engineer:
- Develop daemons in Rust that interface with embedded systems using low- level protocols
- Implement communication interfaces between embedded systems and higher-level processes
- Integrate C code for specific hardware interfaces
- Contribute to the design and implementation of fault-tolerant systems
- Collaborate closely with the Electrical Engineering team to ensure optimal software-hardware integration
- Create and maintain comprehensive documentation for APIs and system architectures
- Contribute to the continuous improvement of our development processes and tools
Key Skills:
- Proven experience in embedded systems development using Rust
- Knowledge of or adaptability to Linux-based development (Ubuntu)
- Proficiency in integrating C code with Rust projects
- Experience with real-time communication protocols
- Experience with inter-process communication protocols
- Understanding of electronics and ability to communicate effectively with hardware engineers
- Excellent documentation skills
Preferred Skills:
- Familiarity with safety-critical embedded systems in any industry
- Experience with Yocto for embedded systems
- Knowledge of version control systems, particularly Git and GitHub
- Familiarity with CI/CD pipelines
- Experience with project management tools
- Proficiency in scripting languages like Python and Bash
- Understanding of cybersecurity principles for embedded systems
- Knowledge of telemetry and command systems
- Experience with formal verification methods for critical software components
- Experience in implementing Fault Detection, Isolation, and Recovery (FDIR) systems for embedded applications
Tools and Technologies: Rust, C | Scripting languages (Bash/Python) | Ubuntu (development environment) | Yocto (target environment) | Version control using Git
Spire operates a hybrid work model, and this position will require you to work a minimum of three days per week in the office.
Access to US export-controlled software and/or technology may be required for this role. If needed, Spire will arrange the necessary licenses—this is not something candidates need to have before applying. #LI-RK1
Global Perks
🛰️ Name Your Satellite Program (NYSP)
🚀 Launch Attendance
🌴 Generous Time Off Policy
🎓 Education Assistance Program
🥰 Employee Assistance Program (EAP)
📈 Employee Stock Purchase Program (ESPP)
👣 Family Leave
💪 Fitness Reimbursement
🧡 Employee Referral Program
🍉 Healthy snacks & beverages in every office
About Spire
We improve life on Earth with data from space.
Spire Global is a space-to-cloud analytics company that owns and operates the largest multi-purpose constellation of satellites. Its proprietary data and algorithms provide the most advanced maritime, aviation, and weather tracking in the world. In addition to its constellation, Spire’s data infrastructure includes a global ground station network and 24/7 operations that provide real-time global coverage of every point on Earth.
Spire is Global and our success draws upon the diverse viewpoints, skills and experiences of our employees. We are proud to be an equal opportunity employer and are committed to equal employment opportunity regardless of race, color, ancestry, religion, sex, national origin, sexual orientation, age, marital status, disability, gender identity or veteran status.
To help maintain a safe and secure workplace for Spire employees, all candidates who receive a conditional offer will be required to complete a background check. This may include criminal history and employment verification.
Please take a moment to review Spire's Global Data Privacy Notice for Employees, Contractors, Candidates and Visitors, as well as Spire's Privacy Policy.
Kindly be advised that communication regarding your application may come from @spire.com, @recruiting.spire.com, or from Candidate.fyi (our scheduling tool).
Ready to apply?
Apply to Spire