About the Team 

Enterprise Engineering builds integrated, scalable platforms that power Roku’s core Finance, Accounting, Payments, Supply Chain, and HR processes. We use API-first, data-driven, and increasingly AI-enabled designs to automate complex workflows, improve control and compliance, and reduce manual work for our partners.

About the Role 

We’re hiring a Senior Product Manager to lead finance and payouts platforms within Enterprise Engineering, with a strong focus on AI-driven automation. You will own products that support order-to-cash, revenue accounting, financial close, reconciliations, and partner payouts, working across Controllership, FP&A, Tax, Treasury, Payments, Ads Revenue Operations, and Business Systems. 

You’ll define the vision, roadmap, and execution for capabilities that combine robust finance controls with modern engineering and AI - e.g., ML-assisted reconciliations, anomaly detection, intelligent exception routing, and Gen-AI powered tools for finance users. This is a high-impact senior IC role; you will regularly influence senior stakeholders across regions, while partnering closely with engineering leads and architects.

What You’ll Be Doing

• Own strategy & roadmap for finance and payouts platforms, including AI-enabled capabilities (classification, matching, forecasting, GenAI assistants) 
• Deep-dive workflows across revenue, close, reconciliations, payouts and compliance; map pain points and define automation opportunities 
• Write clear, structured product requirements (data contracts, controls, SLAs, UX) that Engineering and Finance can execute on 
• Partner daily with engineering and architecture to make pragmatic design tradeoffs on platforms, integrations, and AI usage 
• Define and track success metrics (automation %, cycle time, error rates, payout and reconciliation accuracy), and iterate based on results 
• Drive change management: clear comms, training, and adoption plans for new platform and AI features 
• Keep a close pulse on team and stakeholder “vibe” – building trust, surfacing risks early, and fostering a low-ego, high-ownership way of working 

We’re Excited If You Have

• 8+ years of product management, including substantial time on internal platforms or business systems 
• Strong experience in Finance/Accounting technology (e.g., ERP, revenue systems, sub-ledger / journal automation, reconciliations, payouts) 
• Demonstrated ability to translate complex accounting and regulatory requirements into scalable product designs 
• Hands-on experience with AI / ML or intelligent automation in business processes (e.g., matching, anomaly detection, NLP/GenAI assistants, rules + ML hybrids) 
• Strong systems thinking: comfortable with APIs, data models, integrations, monitoring and controls 
• Excellent written and verbal communication; able to tell a crisp story to executives, Finance stakeholders, and engineers 
• Proven track record working effectively across time zones and cultures, maintaining a healthy and productive team “vibe” 
• Experience in media, advertising, or digital platforms with complex revenue and payout models 
• Background in Finance/Accounting (e.g., CPA, Chartered Accountant, or MBA with finance emphasis)

#LI-AB3

POS-32553

Job Description

At HubSpot, we aim to give employees the same thoughtful, high-quality experience we offer our customers, every day of their journey with us — from their first day in the office to their last. As part of the Global Facilities team, the Senior Manager, Facilities – Americas leads operations across our Americas offices, ensuring safe, reliable, and inspiring workplaces where employees and visitors can do their best work.

This role owns day-to-day facilities operations and workplace experience for our directly leased and partner-managed spaces in the Americas, manages regional vendors and building relationships, and leads a distributed team of coordinators and contingent staff. You will partner closely with Real Estate, Security, Business Technology, Workplace Experience and other key stakeholders to deliver a data-informed, employee-centric facilities strategy that scales with HubSpot’s growth.

In this role you will

Regional leadership & team management

• Lead and develop a high-performing regional facilities team (full-time, temporary, and contractor staff) across multiple Americas locations (e.g., Cambridge, San Francisco, Bogotá), providing coaching, direction, and day-to-day support.
• Set clear goals and priorities aligned to global Facilities and drive consistent operational standards across sites.
• Delegate and oversee work through our internal ticketing system, ensuring timely, high-quality responses to employee and stakeholder requests.

Facilities operations & maintenance

• Own day-to-day facilities operations for the Americas offices, including office readiness, space standards, and preventative maintenance for core building systems (HVAC, plumbing, electrical, furniture, fixtures, and equipment).
• Coordinate and resolve building and infrastructure issues (e.g., furniture failures, water heater problems, IDF/MDF spaces) in partnership with vendors, building engineers, and internal teams, from initial triage through to resolution and communication.
• Ensure that meeting rooms, cafes, collaboration spaces, and wellness areas meet high standards of quality, functionality, and cleanliness, supporting employee productivity and comfort.
• Maintain and update team workflows for all americas offices 

Vendor, building & contract management

• Serve as the primary Facilities point of contact for property managers, landlords, and key building stakeholders across the Americas region, maintaining strong relationships and clear operating rhythms.
• Source, scope, and manage vendors for services such as janitorial, carpet and floor care, furniture, blinds, mechanical/plumbing, and specialty trades — including obtaining quotes, validating scope, scheduling work, and monitoring performance.
• Partner with Procurement and Finance on purchase requests, POs, and cost optimization (e.g., scheduling to avoid overtime labor where possible, aligning work with building access windows).

Workplace experience & front-of-house support

• Ensure a consistently excellent front-of-house and visitor experience in Americas offices, including reception standards, wayfinding, and event support in collaboration with on-site teams.
• Oversee coordination of mail, shipping/receiving, and logistics, including high-value and international shipments in partnership with Business Technology and external carriers.
• Support office events, intentional gatherings, and other on-site activities by ensuring facilities, services, and vendors are aligned to program needs.
• Manage large office moves, terminations including desk assignments. 
• Maintain and update floorplans when changes happen or new offices open, this includes updating the CAFM system to ensure floorplans are up to date.
• Review and coordinate parking assignments notifying the appropriate individuals to provide access.

Health, safety, security & emergency readiness

• Act as a key regional contact for facilities-related emergencies, coordinating with Security, IT, and local building teams to respond to incidents across Americas sites (e.g., IDF/MDF issues, building systems failures, safety concerns).
• Maintain and contribute to emergency contact lists, playbooks, and on-site procedures for multiple locations, ensuring information is current, accurate, and visible to the right stakeholders.
• Partnering with Security and local offices leads to support physical security practices (e.g., access control, cameras, vendor access) and align with HubSpot’s safety expectations.

Projects, space changes & cross-functional collaboration

• Lead and support facilities components of office projects in the Americas (e.g., reconfigurations, furniture changes, programmatic improvements, capital projects) in partnership with Real Estate, Construction partners, BT, and local stakeholders.
• Collaborate closely with global Facilities and Real Estate peers to ensure alignment on standards, data, and reporting, and to share best practices across regions.
• Use ticketing and space data to identify trends, propose improvements, and inform prioritization and investment decisions across the Americas portfolio.

Documentation, communication & knowledge sharing

• Maintain and enhance Facilities documentation for Americas offices, including wiki content, emergency information, operating procedures, and office-specific guides.
• Communicate proactively with employees, partners, and leadership about facilities work, impacts, and timelines, ensuring transparency and building trust.

Our ideal candidate

• Has 7+ years of experience in facilities management, workplace operations, property management, or a related field, including multi-site responsibility and complex office environments.
• Has at least 5+ Years of people management experience, leading and developing distributed teams and working with contingent staff and vendors.
• Demonstrates strong vendor and stakeholder management skills and is comfortable working directly with landlords, property managers, and specialty contractors to solve operational issues.
• Is highly organized, able to prioritize across multiple offices, manage competing deadlines, and stay calm and effective in time-sensitive or emergency situations.
• Communicates clearly and empathetically in writing and in person, tailoring their style for employees, senior leaders, vendors, and building teams.
• Is data-informed and comfortable using ticketing systems and basic reporting to spot patterns, drive improvements, and measure the impact of facilities programs.
• Brings a strong customer-first mentality, with a passion for creating inclusive, welcoming, and accessible spaces for all employees and visitors.
• Aligns with HubSpot’s HEART values and is eager to collaborate across regions and functions to help our global team thrive.

Knowledge of Health & Safety practices, building systems, environmental sustainability, and physical security is a strong plus. Additional languages are a plus.

Diversity & inclusion

Confidence can sometimes hold people back from applying for a role, but there’s no such thing as a “perfect” candidate. HubSpot is a place where everyone can grow, so however you identify and whatever background you bring, please apply if this role excites you and you’re eager to support our teams across the Americas every day.

About HubSpot

HubSpot (NYSE: HUBS) is a leading customer relationship management (CRM) platform that provides software and support to help businesses grow better. We build marketing, sales, service, and website management products that start free and scale to meet our customers’ needs at any stage of growth. We’re also building a company culture that empowers people to do their best work and supports a diverse, inclusive workplace.

Thanks to the work of every employee globally, HubSpot has been recognized for our culture and as a great place to work by Glassdoor, Great Place to Work, Comparably, Fortune, Entrepreneur, and more. Today, thousands of employees work across the globe in HubSpot offices and remotely.

By submitting an application, candidates agree that HubSpot may collect their personal data for recruiting, global organization planning, and related purposes, as outlined in HubSpot’s Privacy Notice.

The Senior Employer Branding Manager is responsible for developing and executing strategies that highlight our culture, values, and employee experience to attract top talent and engage current employees. This role combines storytelling, content creation, video and photography production, and data-driven program design to position CMT as an employer of choice. You’ll own the employee-facing content that shapes how it feels to work here — from the company newsletter to the videos and photos that show the real humans behind the mission — and you’ll support the in-person events that bring our culture to life. This role reports to the Head of Branding and Internal Communications.

Responsibilities:

• Develop and lead the execution of a comprehensive employer branding strategy aligned with CMT’s culture and talent goals
• Own the company newsletter end-to-end — editorial calendar, writing, editing, and measurement — making it something employees actually open and read
• Craft compelling content across written, social, video, and photo formats (social posts, career site updates, blogs, internal comms, employee spotlights, team stories, recruiting videos, event recaps) that highlights our mission, values, and employee experience, ensuring consistency across all touchpoints
• Build and run crowdsourced content programs that get people across the company creating — employee creator programs, content challenges, employee advocacy — equipping teammates with templates, prompts, and light coaching so the stories come from the people living them
• Partner with People Operations, Marketing, and Leadership to design campaigns that engage potential candidates and inspire current employees
• Analyze eNPS, engagement survey data, and other employee sentiment metrics to identify what’s working and where to invest — then design programs that move the numbers
• Monitor and manage CMT’s employer reputation across online sources where candidates and employees rate us — Glassdoor, LinkedIn, Google, Indeed, Comparably, Built In, and emerging platforms — tracking sentiment, responding to reviews, surfacing themes for leadership, and building proactive engagement strategies
• Manage external partners when needed — videographers, photographers, freelance writers, designers, and agencies — keeping work on brand, on schedule, and on budget
• Provide general support for in-person employee and recruiting events — offsites, all-hands, career fairs, campus recruiting, ERG events — from planning through on-site execution
• Analyze campaign performance and employer brand metrics to refine strategies and ensure alignment with organizational objectives
• Lead projects to amplify our presence in the job market, including developing employee advocacy programs, applying for workplace awards, and partnering with industry organizations
• Work across teams to identify opportunities for alignment between employer branding efforts and broader brand and content goals
• Stay updated on employer branding trends, tools, and technologies to keep strategies fresh and competitive
• Complete any additional tasks as they arise

Qualifications:

• Bachelor’s degree or equivalent years of experience and/or certification in Marketing, Communications, or a related field
• 5+ years of experience in employer branding, internal communications, talent marketing, content creation, or a related discipline
• Proven ability to develop and execute strategic branding initiatives that deliver measurable results
• Exceptional storytelling skills, with experience crafting engaging content across written, social, video, and photo formats
• Fluency with video editing — you can take raw footage and turn it into something worth watching, using tools like Adobe Premiere, Final Cut, CapCut, or similar
• Comfortable behind a camera — shooting and editing photography for newsletters, social, the career site, and on-site event coverage
• Experience building programs that get other people creating — employee advocacy, creator programs, crowdsourced content — and the coaching instincts to make non-marketers comfortable contributing
• Analytical mindset — comfortable working with eNPS, engagement survey data, and campaign performance metrics, and translating what you find into programs that actually move the numbers
• Experience managing external creative partners (videographers, photographers, freelancers, agencies) on brand, on schedule, and on budget
• Strong project management skills, with the ability to manage multiple priorities and stakeholders effectively
• Comfortable providing hands-on support for in-person events — logistics, setup, run-of-show, on-site execution
• Excellent interpersonal skills, with a demonstrated ability to work collaboratively across teams and departments
• Proficiency in social media platforms, content management systems, and employer branding tools (LinkedIn Talent Brand / Careers Pages / Life Tab, Canva, or similar)
• A solution-oriented mindset with a proactive approach to problem-solving
• Writing and content samples / portfolio required with application — please include examples of written content, video, and any employee-facing programs you’ve built

Nice to Haves:

• Experience with motion graphics, animation, or more advanced video production
• Experience with workplace awards submissions (Built In, Glassdoor, Great Place to Work, etc.)
• Familiarity with HR systems and engagement platforms (Greenhouse, Culture Amp, Lattice, or similar)

Compensation and Benefits:

• Fair and competitive salary based on skills and experience, and annual performance bonus
• Equity may be awarded in the form of Restricted Stock Units (RSUs)
• Medical, Dental, Vision and Life Insurance, matching 401k, short-term & long-term disability and parental leave
• Unlimited Paid Time Off including vacation, sick days & public holidays
• Flexible scheduling and work from home policy depending on role and responsibilities

Additional Perks:

• Work on a mission with real impact: crashes prevented, injuries avoided, lives protected around the world
• Join an industry leader — 65 million drivers protected, powering 140+ programs across 25 countries
• Be part of the team inventing the future of mobility and road safety
• Move fast, own outcomes, do work that matters
• High ownership, small teams, and direct access to leadership — no layers between your work and its impact
• Unlimited PTO, flexible scheduling, competitive salary, annual performance bonus, RSUs, and full benefits including medical, dental, vision, and 401k match
• Summer Fridays
• Comprehensive wellness, education, and employee assistance programs

About Cambridge Mobile Telematics:

Cambridge Mobile Telematics (CMT) is the world’s largest telematics and AI company for safer mobility. Its mission is to make the world’s roads and drivers safer. The company’s AI-driven platform, DriveWell Fusion®, proactively identifies and reduces driving risk, leading to fewer crashes and injuries. To date, CMT’s technology has helped prevent over 126,000 crashes worldwide. CMT enables partners to measure risk, detect crashes, provide life-saving assistance, and streamline claims. Headquartered in Cambridge, MA, CMT operates globally with offices in Budapest, Hungary; Chennai, India; Seattle, Washington; Tokyo, Japan; and Zagreb, Croatia. Learn more at www.cmt.ai.

The Role:

Reporting to the Head of Contracts, the Senior Manager, Contracts - Clinical will serve as the primary contracts professional working closely with the Clinical function, particularly Clinical Operations. This is a hands-on, high-volume role responsible for the full lifecycle of clinical site agreements and ancillary clinical contracts across Nuvalent’s global study portfolio, currently spanning four concurrent studies including a Phase 3 randomized controlled trial.

The ideal candidate has deep experience in global clinical site contracting at a sponsor company or CRO, is comfortable operating with significant autonomy, and has the judgment to know when to resolve an issue independently and when to escalate. This role works directly alongside a peer team of Senior Contracts Managers within a contracts department that is growing alongside Nuvalent’s pipeline.

Responsibilities:

Clinical Site & Study Agreements

• Draft, review, negotiate, and execute Clinical Trial Agreements (CTAs) with academic medical centers, community research sites, and international investigator sites across global markets.
• Manage the full contract lifecycle from initial draft through execution, amendment, and close-out across a high-volume, multi-study portfolio.
• Coordinate Informed Consent Form (ICF) review as needed in connection with site-level contracting.
• Negotiate and process Work Orders (WOs) and Change Orders (COs) in coordination with Clinical Operations and relevant CRO or vendor counterparties.
• Serve as the primary contracts point of contact for site administrators, legal counsel, and CRO contract teams, maintaining productive counterparty relationships through complex negotiations.

Ancillary Clinical Contracts

• Draft, review, and negotiate Confidential Disclosure Agreements (CDAs) and Non-Disclosure Agreements (NDAs) for clinical partnerships and site-level engagements.
• Manage consulting agreements for clinical investigators, key opinion leaders, and clinical consultants engaged by Clinical and Clinical Operations, with appropriate escalation of HCP engagements for compliance review.
• Support statements of work and related agreements for Clinical and Clinical Operations vendors.

Contract Operations & Process

• Maintain accurate, complete, and timely contract records in Nuvalent’s contract management system (Agiloft), including status updates, executed document storage, and obligation tracking.
• Apply and enforce departmental file naming conventions, version control standards, and repository management protocols.
• Provide timely contract status visibility to Clinical and Clinical Operations business owners and serve as a reliable point of contact for internal stakeholders throughout the contract lifecycle.
• Identify issues requiring escalation and engage appropriate internal resources — including Legal, QA, Regulatory, Clinical Operations, Finance, IT, and Compliance — or external resources including CRO counterparties, outside counsel, or the Data Privacy Officer (DPO).
• Contribute to negotiation playbooks, standard fallback positions, and contract templates for clinical contract types.
• Coordinate with Legal and the DPO on data privacy provisions in clinical agreements, including GDPR data processing terms for EU and international site agreements.
• Utilize AI-assisted contract review tools as integrated into departmental workflow in accordance with established Nuvalent guidance.
• Lead or co-lead department initiatives to support an expanding organization.

Competencies Include:

• Detail and process oriented, with strong organizational skills and the ability to manage a high-volume, multi-study contract portfolio across competing deadlines and shifting priorities.
• Strong negotiation, problem solving, and communication skills, with the ability to hold a position, find common ground, and close without unnecessary escalation.
• Flexibility with changing priorities and ability to think critically under pressure.
• Ability to work in a collaborative environment and build effective working relationships across the organization, including with external counterparties such as site administrators, CRO contract teams, and outside counsel.
• Sound judgment in recognizing when to resolve independently and when to bring in the right internal or external resources.
• Able to thrive in a remote/virtual environment.

Qualifications:

• Minimum of 7 years of contracts experience in the biopharmaceutical or clinical research industry, with at least 4 years focused on vendor agreements, clinical site agreements, investigator agreements, or study start-up contracting; sponsor-side experience preferred, CRO-side experience considered.
• Demonstrated experience negotiating CTAs, WOs, COs, CDAs, and HCP consulting agreements at volume across multiple concurrent studies.
• Direct experience contracting with international clinical sites and working knowledge of applicable legal and regulatory requirements including GDPR data processing considerations.
• Working knowledge of GCP, ICH guidelines, and FDA regulations governing clinical research and their practical implications for contract terms.
• Familiarity with IRB processes and their intersection with site-level contracting.
• Proficiency with contract lifecycle management systems; experience with Agiloft, Ironclad, DocuSign CLM, or comparable platforms required. Agiloft experience a plus; training will be provided.
• Oncology experience preferred; relevant experience from adjacent therapeutic areas will be considered.
• Familiarity with AI-assisted contract review tools a plus.
• Bachelor’s degree or equivalent experience required.

Additional Information:

Nuvalent is committed to fair and equitable compensation practices, aiming to provide employees with competitive total rewards packages.

The targeted salary range reflects what Nuvalent reasonably and in good faith expects to offer for this position at the time of posting, but the final salary determination may be within or outside this range based on various factors, including, but not limited to, experience, skills, education, and market factors.  The range will be reviewed regularly and is subject to change.

Nuvalent also offers a comprehensive benefit package to support our employees at each stage of their career, financial, health, and well-being journey, including medical, dental, and vision insurance, 401(k) retirement savings plan, generous paid time off (including a summer and winter company shutdown), and much more.

Your Impact at LILA

Lila Sciences is seeking a detail-oriented and process-driven HR Generalist (Contract) to join our HR Operations team. This role will serve as the execution backbone of our HR Operations function. The HR Generalist will handle the day-to-day administration of the employee lifecycle, systems management, benefits support, and cross-functional HR tasks. This is a high-execution role best suited for someone who takes pride in doing administrative work accurately and efficiently, thrives on process ownership, and is energized by bringing order and consistency to a growing organization.

What You'll Be Building

Employee Lifecycle, Onboarding & Offboarding

• Execute end-to-end pre-boarding and onboarding processes, including coordination of IT intake, systems access setup, and employee introduction materials
• Identify and implement improvements to pre-boarding workflows to increase consistency and reduce manual effort
• Support offboarding administration, including exit paperwork and required system updates
• Process administrative HR actions across the employee lifecycle: new hires, transfers, internal role changes, manager changes, and terminations
• Generate employment letters (transfer, termination, etc.) and manage signature request workflows
• Maintain and organize employee documentation in accordance with compliance requirements

Immigration & Benefits Administration

• Manage immigration paperwork and coordinate with external counsel or vendors on active cases under HR Operations Manager guidance
• Administer benefits tasks that cannot be automated, including enrollment support and data entry
• Provide leave administration support as needed, in coordination with HRBPs

HR Inbox & Employee Support

• Manage the HR team inbox: triage, respond to, and route inquiries related to onboarding/offboarding, immigration, benefits, and company policies
• Serve as a reliable first point of contact for employee and manager HR questions, ensuring timely and accurate responses, and escalating complex cases appropriately

Process & Compliance

• Own the I-9 compliance process end-to-end: complete Section 2 verification for all new hires, manage re-verification for expiring work authorization documents, maintain organized and audit-ready I-9 records, and coordinate E-Verify submissions where applicable
• Collaborate with HR Operations to document, standardize, and improve HR workflows and procedures

What You’ll Need to Succeed

• 1–3+ years of HR experience with a focus on HR operations, administration, or HR coordination
• Hands-on experience with HRIS platforms; HiBob and/or ADP experience is a plus
• Strong attention to detail and a track record of accurate, high-volume administrative work
• Comfortable managing multiple competing priorities with minimal supervision
• Clear and professional communicator (written and verbal)
• Ability to handle sensitive, confidential HR information with discretion
• Demonstrated commitment to process improvement and operational consistency
• Local to the Cambridge, MA area; able to work hybrid (averaging ~3 days/week onsite based on need)

Bonus Points For

• Experience with ATS platforms (e.g., Greenhouse)
• Direct experience administering the I-9 process
• Experience with process documentation and process flow documents
• Familiarity with immigration processes and vendor coordination
• Experience supporting benefits administration or leave management
• Comfort with ambiguity in a fast-paced, evolving environment

Overview of the role:

As the Product Manager for Software / Applied AI at Lila, you will help build the first truly AI-native system of record for scientific discovery. We are looking for product leaders who can dive deep into a specific domain and own it completely.

Whether your strengths align best with our core software platform or our cutting-edge agentic science offerings, you will be embedded with a dedicated scrum team to solve complex, full-stack challenges. You will sit at the intersection of commercial, engineering, design, and scientific research, building the tools that accelerate the next generation of scientific discovery.

We are hiring for a wide range of function areas, and seniority levels — final title and level will be decided at the offer stage. Priority areas include 1) data, 2) ML / computational tooling, 3) scientific agents, and 4) harness & evals.

Location:

Ability to work from our San Francisco, CA; or Cambridge, MA office 3-5 days per week.

Responsibilities:

Deep Domain Ownership:

We will match your unique product strengths to a specific scrum team, where you will go deep, define the roadmap, and become the absolute subject matter expert for that product area. That said, we operate as one product team and collaborate closely.

Full-Stack Product Execution:

From designing user-facing scientific workflow tools to shaping the underlying data infrastructure that powers our AI models, you will define requirements and guide execution across the entire stack.

The intelligence platform for Science:

Build intuitive, powerful software that scientists actually want to use. You will be responsible for translating incredibly complex scientific workflows into scalable, elegant digital products.

Cross-Functional Orchestration:

Lead the dialogue between our research scientists (who push the boundaries of what's possible) and our engineering teams (who build robust, scalable systems), ensuring we ship high-impact, cohesive products.

Qualifications:

Core Product Experience:

Product Management experience building complex B2B SaaS, data-heavy platforms, or highly technical software products.

The Full-Stack Mindset:

You are comfortable navigating both the user experience of a complex workflow and the technical realities of the backend architecture required to support it.

Bias for Action in Complexity:

You thrive in ambiguous environments. You can take a vague, highly technical customer request and turn it into a clear, prioritized roadmap for your engineering team in days, not weeks.

Operational Rigor:

You care deeply about the "how" — how the product is built, how it performs, and how it directly impacts the end user's daily work.

Preferred Skills:

Scientific Background:

A degree or deep practical experience in the hard sciences (materials science, chemistry, biology, etc.).

Building for Scientists:

Direct experience building software, tools, or platforms specifically designed for scientific researchers or lab environments.

Startup DNA:

Experience as an early-stage product manager who knows how to move fast, iterate, and build from 0 to 1.

The Role:

Reporting to the Director, Global Regulatory Affairs, the Senior Manager, Regulatory Affairs role will integrate regulatory strategic development, submission management expertise, and hands-on execution to support the IND/CTA stage of development through NDA/MAA.

The Senior Manager, Regulatory Affairs will contribute to the development and implementation of regulatory strategy as a member of the global regulatory affairs function and clinical study team(s). This role will manage the process for preparation, submission and internal review and approval of regulatory documents, including providing technical regulatory input for global documents to streamline development.

The Senior Manager, Regulatory Affairs must be kept current, innovative, and compliant with the constant changing Health Authority requirements to facilitate regulatory processes and compliance maintenance from IND/CTAs through NDA/MAA. 

Responsibilities:

• Participates as a regulatory representative for Clinical Study Team (CST) on development programs assigned working closely with product development team (PDT) lead to develop the global regulatory strategy; work closely with regulatory operations and program management to track timelines and ensure deliverables are achieved
• As part of the regulatory clinical study team, you will support preparation, review, compilation, and execution of submissions for regulatory agencies for US and ROW (e.g., IND/CTAs, NDA/MAA, DSURs, Amendments, and Responses to Regulatory Agency Requests for Information, etc.)
• Provide regulatory guidance and support to senior regulatory affairs members on various projects, as needed, to further development programs (pediatric development planning, regulatory interactions, NDA planning)
• Ensure collaboration with and coordination of cross-functional project teams for timely execution of regulatory submissions, maintaining compliance with global regulatory standards and commitments, and providing regulatory guidance and oversight
• Support regulatory operations during the regulatory submissions handoff process, as the primary point of contact for external publishing vendors, ensuring submission packages are accurate, formatted correctly, and validated.
• Maintain the regulatory information system and ensure proper archiving, searchability, and accessibility of regulatory content including correspondence with regulatory agencies
• Manage regulatory submission processes, develop and maintain regulatory tracking tools and infrastructure, as assigned Conduct regulatory intelligence and competitive intelligence and summarize key impacts to global strategy development teams, as appropriate
• Ensure compliance with internal SOPs, regulations and applicable laws. Drafts and reviews Regulatory Affairs SOPs and work instructions and provides Regulatory feedback on other departmental SOPs, where required

Competencies Include:

• Excellent attention to detail and ability to complete efficient and detailed technical data review
• Excellent organization, communication, and multi-tasking skills
• Exceptional interpersonal skills and experience contributing to productive teams and fostering cross functional relationships
• Strong desire to contribute as a member of an engaged and collaborative cross-functional project development team

 Qualifications:

• 6-8 years of experience in Regulatory Affairs or combination of education and direct experience.
• Bachelor or advanced degree in a scientific field or equivalent work experience is required.  Master’s degree a plus.
• Proven experience in evaluation, preparation and compilation of quality dossiers in all required formats and/or experience in regulatory processes.
• Solid understanding of the e-CTD specifications for electronic submissions.
• Knowledge and practical understanding of ICH Guidelines regarding GMP/GCP, ICH Guidelines for CTD/eCTD and CDER requirements for the drug approval process.
• Previous participation in preparing and/or leading regulatory submissions (IND, CTA, NDA, etc.). Experience with preparing meeting packages is a plus.
• Experience in interpretation of regulations, guidelines and precedents related to drug development in the US and EU.
• Strong understanding of regulatory eCTD structure and clinical trial conduct and design
• Proficiency with electronic submission publishing software and document management information systems (i.e., docuBridge, Veeva Vault RIM)
• Ability to plan, prioritize and contribute to work and projects in a systematic and efficient manner with emphasis on streamlining processes

Additional Information:

Nuvalent is committed to fair and equitable compensation practices, aiming to provide employees with competitive total rewards packages.

The targeted salary range reflects what Nuvalent reasonably and in good faith expects to offer for this position at the time of posting, but the final salary determination may be within or outside this range based on various factors, including, but not limited to, experience, skills, education, and market factors.  The range will be reviewed regularly and is subject to change.

Nuvalent also offers a comprehensive benefit package to support our employees at each stage of their career, financial, health, and well-being journey, including medical, dental, and vision insurance, 401(k) retirement savings plan, generous paid time off (including a summer and winter company shutdown), and much more.

Flagship Pioneering is a scientific innovation engine that invents and builds companies that change the world. We bring together the greatest scientific minds with entrepreneurial company builders and assemble the capital to allow them to take courageous leaps in human health, sustainability, and beyond. 

What sets Flagship apart is our ability to advance biotechnology by uniting life science innovation, company creation, and capital investment under one roof in a way that is largely without precedent. Our team of scientists, entrepreneurial leaders, and professional capital managers are each aligned around an institutionalized process that enables us to innovate and create breakthroughs for the benefit of people and planet.

Many of the companies Flagship has founded have addressed humanity’s most urgent challenges: vaccinating billions of people against COVID-19, curing intractable diseases, improving human health, preempting illness, and feeding the world by improving the resiliency and sustainability of agriculture.

Flagship has been recognized twice on FORTUNE’s “Change the World” list, an annual ranking of companies that have made a positive social and environmental impact through activities that are part of their core business strategies, and has been named four times to Fast Company’s annual list of the World’s Most Innovative Companies.

Position Overview

Flagship Pioneering is seeking an experienced and strategic Vice President or Senior Vice President, Total Rewards and People Operations to lead the design, management, and evolution of Total Rewards programs and key people infrastructure across our ecosystem. The scope of this role spans compensation, executive compensation, equity, benefits, people operations, and people analytics for Flagship and its portfolio of companies.

This is a highly visible leadership role requiring deep expertise in compensation strategy and private-company equity, as well as the ability to operate effectively across a complex, fast-paced, and highly matrixed environment. The ideal candidate will bring strong executive presence, sound judgment, and the ability to translate business strategy into scalable people programs that support growth, innovation, and organizational effectiveness.

This leader will oversee an established team across Compensation, Benefits, People Operations, and People Analytics, and will be expected to shape a modern, market-relevant Total Rewards philosophy, refine equity and incentive structures, advance benefits strategy, and drive people insights that support executive decision-making.

Key Responsibilities

Total Rewards Strategy and Leadership

• Lead the strategy, design, and ongoing evolution of Flagship’s global Total Rewards philosophy across compensation, executive compensation, equity, benefits, and other reward programs. 
• Serve as the principal architect of rewards strategy, recommending program direction to senior leadership and ensuring alignment with business priorities, talent strategy, and financial objectives. 
• Develop and refine salary structures, incentive frameworks, equity guidelines, and market positioning approaches across a global footprint. 
• Oversee job architecture and leveling governance in support of internal equity, talent management, and scalable compensation decision-making. 
• Guide annual compensation planning processes, including merit, bonus, promotion, and other pay actions, in partnership with HR, Finance, and business leadership. 
• Partner closely with Talent Acquisition and HR Business Partners on executive and broad-based offer strategy, market competitiveness, and internal equity. 
• Lead the continued evolution of executive compensation and broad-based equity strategy across Flagship and applicable portfolio companies. 

Equity and Incentive Design

• Provide strategic leadership for complex equity and long-term incentive programs, including private-company equity structures and alternative long-term incentive constructs. 
• Oversee equity strategy, governance, and operational execution through the team, ensuring strong program design and scalable administration. 
• Partner with senior leadership on the design and refinement of incentive and ownership frameworks that support attraction, retention, and long-term value creation. 
• Bring familiarity with innovative and non-traditional compensation approaches, including profits interests, carried interest, and related long-term incentive structures. 

Benefits Strategy

• Lead benefits strategy across health and welfare, retirement, leave, and ancillary programs, ensuring programs remain competitive, sustainable, and aligned with organizational values and workforce needs. 
• Partner with the Benefits leader and external advisors to evaluate plan design, funding, market trends, vendor performance, and evolving regulatory requirements. 
• Support harmonization and modernization of benefits strategy where appropriate across a diverse and growing ecosystem. 

People Operations

• Oversee key People Operations functions, including onboarding, offboarding, employee lifecycle processes, policy administration, compliance workflows, service delivery, and operational process excellence. 
• Ensure people processes are scalable, well-governed, and designed to support a high-quality employee and manager experience. 
• Partner effectively across HR, Payroll, IT, Legal, and Finance to improve operational efficiency and strengthen people-related infrastructure. 
• Provide leadership on HR compliance, as well as compensation- and benefits-related compliance considerations, in partnership with internal and external experts as appropriate. 

People Analytics

• Lead the People Analytics agenda, with an emphasis on generating insights that support executive decision-making across workforce planning, hiring, retention, compensation, and organizational effectiveness. 
• Oversee dashboards, reporting, and analytical frameworks that inform leaders including the CEO and CFO. 
• Translate data and analysis into actionable recommendations in partnership with HR Business Partners and business leaders. 
• Advance a thoughtful, increasingly sophisticated analytics capability that supports better people decisions across Flagship and the broader ecosystem. 

Portfolio Company Partnership

• Advise and support portfolio company leaders on Total Rewards strategy, with involvement calibrated to company stage, maturity, and business need. 
• Tailor rewards frameworks and guidance for a range of company stages while maintaining sound governance and alignment with broader talent and value creation goals. 
• Present recommendations and insights to portfolio company leadership and boards as needed. 

Leadership and Team Development

• Lead, develop, and inspire a multi-functional team spanning Compensation, Benefits, People Operations, and People Analytics. 
• Foster strong collaboration across functional teams and help continue building a high-performing, service-oriented, and strategically focused organization.
• Manage external consultants, brokers, survey providers, and other key vendors in support of rewards strategy and operational excellence. 

Qualifications

• 15+ years of progressive experience in Total Rewards, with significant depth in compensation strategy and experience leading broad, multi-functional teams. 
• Deep expertise in compensation design, market benchmarking, executive compensation, incentive strategy, and private-company equity. 
• Strong familiarity with alternative long-term incentive structures, including profits interests, carried interest, and other innovative ownership or reward constructs. 
• Experience leading or advising on benefits strategy, including health and welfare, retirement, leave, and ancillary offerings. 
• Experience overseeing or partnering closely with People Operations and People Analytics functions in complex organizations. 
• Demonstrated success operating in high-growth, founder-led, venture-backed, private equity, or similarly dynamic business environments. 
• Experience supporting global workforces and navigating matrixed organizations with multiple stakeholders and business models. 
• Strong executive presence with the ability to influence senior leaders, present compelling recommendations, and operate as a trusted advisor. 
• Proven ability to translate data and market insights into practical, business-relevant decisions and action plans. 
• Experience working with boards, founders, and senior executive stakeholders preferred. 
• Prior life sciences or biotechnology experience preferred, but not required. 

Why Join Flagship Pioneering?

This is a rare opportunity to play a critical role in shaping how a highly innovative organization rewards, supports, and scales exceptional talent. As Senior Vice President, Total Rewards and People Operations, you will operate at the intersection of business strategy, organizational design, and cutting-edge science, helping to build and evolve the people infrastructure that supports transformative work in human health and sustainability.

At Flagship, we recognize there is no perfect candidate. If you have some of the experience listed above but not all, please apply anyway. Experience comes in many forms, skills are transferable, and passion goes a long way. We are dedicated to building diverse and inclusive teams and look forward to learning more about your unique background.

Recruitment & Staffing Agencies: Flagship Pioneering and its affiliated Flagship Lab companies (collectively, “FSP”) do not accept unsolicited resumes from any source other than candidates. The submission of unsolicited resumes by recruitment or staffing agencies to FSP or its employees is strictly prohibited unless contacted directly by Flagship Pioneering’s internal Talent Acquisition team. Any resume submitted by an agency in the absence of a signed agreement will automatically become the property of FSP, and FSP will not owe any referral or other fees with respect thereto.

#LI-NM1

The salary range for this role is $300,000 - $400,000. Compensation for the role will depend on a number of factors, including a candidate’s qualifications, skills, competencies, and experience. Flagship Pioneering currently offers healthcare coverage, annual incentive program, retirement benefits and a broad range of other benefits. Compensation and benefits information is based on Flagship Pioneering's good faith estimate as of the date of publication and may be modified in the future.

The Opportunity

We are seeking a highly motivated Manager of Financial Planning & Analysis (FP&A) to join our established finance team at a well-positioned, clinical-stage precision medicine company in Kendall Square. This is an excellent opportunity for a finance professional who thrives in a dynamic, collaborative environment and is eager to make a meaningful impact across the organization.

This role will report to the Senior Director of FP&A and will play a key role in supporting our development organization through accrual reporting, planning, and analytical activities as well as supporting our recurring management reporting deliverables

Your Role

• Track and analyze clinical site budgets, providing visibility into spend and key trends
• Support the analytics for our clinical trials including the clinical accruals process, and business partnering with key cross-functional stakeholders
• Preparation and delivery of key monthly reporting including monthly financial reporting and headcount analytics
• Trusted FP&A business partner to our G&A departments (Finance, IT, HR, Legal, and Operations)
• Perform ad hoc financial analysis to support decision-making across the development organization
• Assist with budgeting, forecasting, and long-range planning processes
• Prepare presentations and materials for cross-functional partners, translating data into clear and compelling financial insights
• Continuously improve financial processes, models, and reporting tools

Your Background

• Bachelor’s degree in Accounting, Finance, or related field (required)
• 5+ years of progressive experience in finance or accounting (biotech or life sciences experience preferred)
• Strong proficiency in Microsoft Excel and PowerPoint (required)
• Experience with Adaptive Planning or similar financial planning tools (preferred)
• Solid understanding of financial statements, budgeting, and forecasting processes
• Strong analytical, problem-solving, and communication skills
• Ability to manage multiple priorities and work effectively in a fast-paced environment
• Detail-oriented with a high degree of accuracy and accountability

Why Join Us?

• Join a collaborative, well-established finance team
• Contribute to a mission-driven company making a meaningful impact for patients
• Gain exposure to cross-functional teams and senior leadership
• Opportunity for growth and professional development

If you're looking to take the next step in your finance career and want to contribute to a high-impact organization, we’d love to hear from you.

Estimated Salary Range: [$98,000 - $140,000].

The range provided above is based on what we believe to be a reasonable estimate for this job at the time of posting. Actual base salary will depend on a number of factors, including but not limited to, a candidate’s education, experience, skills and location.

#BP1

Your Impact at LILA

Lila is looking for an HR Manager to join the HRBP team and serve as a reliable, day-to-day people partner to assigned managers and client groups. You will support the execution of people programs, help managers navigate employee relations and performance topics, and contribute to building a strong, consistent culture as the organization scales. This role is a strong foundation for growing into a broader strategic HR advisory capacity over time.

What You'll Be Building

• Partner with assigned managers to provide hands-on HR guidance on talent management, employee relations, performance management, and team effectiveness
• Coach managers on people leadership, navigating difficult conversations, and developing their teams
• Drive execution of core HR programs including performance review cycles, compensation planning, and engagement initiatives
• Identify trends in people data and employee feedback to surface insights and flag areas requiring attention
• Collaborate cross-functionally with HR, Legal, and Finance to ensure consistency and compliance across people processes

What You’ll Need to Succeed

• 5–7 years of progressive HR experience, with at least 2 years in an HRBP, HR generalist, or client-facing HR role
• Demonstrated ability to build trusted relationships with managers and leaders across an organization
• Solid knowledge of core HR disciplines including performance management and employment law fundamentals
• Experience coaching managers through complex or sensitive people situations
• Comfort operating in a fast-paced, evolving environment where priorities shift quickly
• Strong judgment and discretion when handling confidential matters

Bonus Points For

• Experience supporting technical or scientific organizations, particularly in biotech, AI, or deeptech
• Familiarity with HRIS and people tools such as HiBob, Udemy, Greenhouse, or similar platforms
• Background in organizational development, change management, or culture-building initiatives
• Experience in a startup or high-growth company where HR processes and infrastructure were still being built
• Comfort using AI tools to improve and scale people processes and programs

Flagship Pioneering is a scientific innovation engine that invents and builds companies that change the world. We bring together the greatest scientific minds with entrepreneurial company builders and assemble the capital to allow them to take courageous leaps in human health, sustainability, and beyond. 

What sets Flagship apart is our ability to advance biotechnology by uniting life science innovation, company creation, and capital investment under one roof in a way that is largely without precedent. Our team of scientists, entrepreneurial leaders, and professional capital managers are each aligned around an institutionalized process that enables us to innovate and create breakthroughs for the benefit of people and planet.

Many of the companies Flagship has founded have addressed humanity’s most urgent challenges: vaccinating billions of people against COVID-19, curing intractable diseases, improving human health, preempting illness, and feeding the world by improving the resiliency and sustainability of agriculture.

Flagship has been recognized twice on FORTUNE’s “Change the World” list, an annual ranking of companies that have made a positive social and environmental impact through activities that are part of their core business strategies, and has been named four times to Fast Company’s annual list of the World’s Most Innovative Companies.

Position Overview

Reporting into theVice President, HR, the Sr.Director Human Resources Business Partner (HRBP) for the Lab Companies will be a key driver of the people strategy for the origination team members of our Pioneering Business Units at Flagship. In this role, the Sr. Director, HRBP will build and sustain relationships with their client group and the broader enterprise. Working closely with their respective Pioneering Business Unit Head, The Sr. Director, HRBP will effectively influence analysis and decision-making in the areas of leadership, talent management and development, succession planning, change management, budgeting and compensation, work force planning, organization development and design, performance management, employee engagement, career ladders and competencies, employee relations and communications.

The Sr.Director, HRBP will collaborate with the other HR Leaders to diagnose needs, develop, and deliver solutions to support our organization. The person in this role should have strong business acumen with proven ability to understand and align business needs with HR solutions to move the business forward in a changing environment. The ideal candidate will effectively influence analysis, accountability, and decision-making in many areas that impact our people.

The Sr. Director, HRBP must have a demonstrated track record of effective coaching and strategic partnerships with senior leaders and their employees, proven leadership skills, experience building teams and organizational design. The Sr. Director, HRBP should be able to demonstrate interpersonal awareness to effectively build and sustain strong client partnerships at all levels with trust and credibility to influence individuals and teams.  The successful candidate will have the ability to identify and develop leaders and be effective in addressing change and transformation. Ability to analyze trends and use metrics to propose and develop solutions is also critical.

Key Responsibilities:

• Serve as a strategic thought partner, change agent, and implementation advisor; be familiar with the strategic plans of the Pioneering Business Unit to help managers translate the business strategy and goals into HR related practices.
• Guide and support senior management and their employees in developing sustainable programs, practices, and behaviors to drive significant cultural change and enhance employee engagement and development.
• Coach and advise managers on building their teams, the effectiveness of their teams, strategic business matters, talent topics and general HR issues.
• Help executives align manager and employee capabilities to the mid-to-long-term business needs.
• Support foundation of new and growing companies while keeping scale in mind including establishing career ladders, organizational structure design and roles and responsibilities.
• Serve as a member of the senior HR Leadership Team, demonstrating enterprise leadership sharing a strong point of view on a variety of topics that may or may not be directly related to their PBU.
• Partner with TA and Enterprise team, assisting with a variety of matters to include interviewing, onboarding, immigration, budget etc.
• Manage the day-to-day Human Resources needs of the Origination Leader and their teams including acting as a point of contact for people tools, processes and programs.
• Act as stewards of the employee experience and Flagship’s culture.

Qualifications: 

• Bachelor's degree with 10-15 years experience in the HR field or
• Master's Degree and 8+ years of progressive HR experience

Preferred Qualifications: 

• Prior Pharma/Biopharma experience, start-up experience helpful
• Proven experience coaching and counseling all levels of staff on a wide variety of issues, and a thorough understanding of performance management systems and State and Federal employment law.
• Exceptional networking, relationship building, judgement and passion with a drive for compromise across different perspectives.
• Ability to translate business vision and strategy into an executable people agenda.
• Knowledge of and ability to apply OD concepts and models, such as team effectiveness, change management, communication styles, facilitation, and leadership development.
• Strengths in working and communicating in a highly matrixed environment, strong collaboration and influencing skills.
• Employee relations experience managing complex workplace matters.
• Demonstrated business acumen and a working knowledge of multiple HR disciplines.

Additional Qualifications:

• Analytical, problem-solving and conflict resolution skills including the ability to diagnose root causes.
• Ability to work in a time sensitive and confidential environment, balancing multiple priorities simultaneously.
• Computer skills in MS office (Excel, PowerPoint, Word), SharePoint, and HRIS (UKG is a plus)

At Flagship, we recognize there is no perfect candidate. If you have some of the experience listed above but not all, please apply anyway. Experience comes in many forms, skills are transferable, and passion goes a long way. We are dedicated to building diverse and inclusive teams and look forward to learning more about your unique background.

Recruitment & Staffing Agencies: Flagship Pioneering and its affiliated Flagship Lab companies (collectively, “FSP”) do not accept unsolicited resumes from any source other than candidates. The submission of unsolicited resumes by recruitment or staffing agencies to FSP or its employees is strictly prohibited unless contacted directly by Flagship Pioneering’s internal Talent Acquisition team. Any resume submitted by an agency in the absence of a signed agreement will automatically become the property of FSP, and FSP will not owe any referral or other fees with respect thereto.

#LI-NM1

The salary range for this role is $220,000 - $269,500. Compensation for the role will depend on a number of factors, including a candidate’s qualifications, skills, competencies, and experience. Flagship Pioneering currently offers healthcare coverage, annual incentive program, retirement benefits and a broad range of other benefits. Compensation and benefits information is based on Flagship Pioneering's good faith estimate as of the date of publication and may be modified in the future.

Flagship Pioneering is a bioplatform innovation company that invents and builds platform companies that change the world. We bring together the greatest scientific minds with entrepreneurial company builders and assemble the capital to allow them to take courageous leaps. Those big leaps in human health and sustainability exponentially accelerate scientific progress in areas ranging from cancer detection and treatment to nature-positive agriculture.   

 What sets Flagship apart is our ability to advance biotechnology by uniting life science innovation, company creation, and capital investment under one roof in a way that is largely without precedent. Our scientific founders, entrepreneurial leaders, and professional capital managers are each aligned around an institutionalized process that enables us to innovate and transform for the benefit of people and planet.   

Many of the companies Flagship has founded have addressed humanity’s most urgent challenges: vaccinating billions of people against COVID-19, curing intractable diseases, improving human health, preempting illness, and feeding the world by improving the resiliency and sustainability of agriculture.  

Flagship has been recognized twice on FORTUNE’s “Change the World” list, an annual ranking of companies that have made a positive social and environmental impact through activities that are part of their core business strategies, and has been twice named to Fast Company’s annual list of the World’s Most Innovative Companies. 

Position Overview: 

Flagship Pioneering is seeking a Senior Manager, HR Operations & Systems to own and evolve our HR systems ecosystem, with primary responsibility for UKG and broad oversight of platforms including Greenhouse and other HR technologies. This role will drive day-to-day administration, governance, integrations, and future-state strategy of HR systems to ensure compliance, enable scalable service delivery, strengthen data integrity, and support a seamless employee experience across the lifecycle. Reporting to the Associate Director, HR Operations & Analytics, this leader will partner closely with HR, Legal, Payroll, Finance, and Enterprise Applications / IT to design system-enabled HR operations that are scalable, well-governed, and built for growth. 

Role Summary 

The Senior Manager, HR Operations & Systems will serve as the business owner for Flagship’s HR systems ecosystem within HR Operations, with primary responsibility for the strategy, administration, optimization, and operational enablement of core HR platforms, including UKG, Greenhouse, and other HR technologies across the employee lifecycle. 

Reporting to the Associate Director, HR Operations & Analytics, this role will partner closely with HR Operations, Talent, Total Rewards, Learning & Culture, Legal, Payroll, Finance, People Analytics, and Enterprise Applications / IT to ensure systems support the HR function in a scalable, compliant, and analytically sound way. 

This leader will help stitch together the HR systems landscape through thoughtful integrations, controls, documentation, and future-state HR tech strategy, while acting as a subject matter expert to IT for implementation and technical design. 

Key Responsibilities 

HR Systems Ownership & Administration 

• Serve as the primary HR business owner for HR systems, with deep ownership of UKG and operational oversight of other HR and talent platforms such as Greenhouse, TalentWall, Crosschq, LinkedIn Recruiter, Pequity, and future tools. 

• Manage day-to-day administration of HR systems, including configuration, permissions, security roles, workflows, testing, issue resolution, release support, and operational documentation. 

• Ensure HR systems are structured and maintained to support scalable service delivery, consistent HR operations, and strong user experience across the employee lifecycle. 

• Maintain system standards, field logic, process flows, and governance documentation to improve consistency and reduce operational ambiguity. 

Systems Architecture, Process Design & Integrations 

• Architect HR systems and processes from an operational perspective, ensuring systems support onboarding, transfers, promotions, offboarding, compliance requirements, and service delivery across the employee lifecycle. 

• Design and optimize integrations across the HR systems landscape, including key connections such as UKG-ADP and Greenhouse-UKG, to improve data flow, reduce manual work, and strengthen downstream reporting and controls. 

• Partner with Enterprise Applications / IT to define technical requirements, integration priorities, testing strategy, and implementation needs; serve as the HR SME for system changes and implementations while IT owns technical implementation and vendor management. 

• Be sufficiently hands-on and technically fluent to configure systems directly where appropriate and to effectively guide or direct technical work when builds are completed by IT or other partners. 

• Identify automation opportunities and future-state improvements across HR systems to improve scalability, reduce friction, and support evolving business needs. 

Compliance, Controls & Governance 

• Partner with HR Operations teammates, Legal, and other stakeholders to ensure systems are designed and configured to enable compliance, controls, audit readiness, and consistent execution of HR processes. 

• Manage system-enabled governance, including permissions, process controls, documentation logic, policy acknowledgement workflows, and audit-supporting records. 

• Help ensure systems support compliance execution across key areas such as documentation completeness, training administration, process controls, and employee record quality. 

• Support the creation of scalable, system-enabled HR ways of working by translating process requirements into governed workflows and operational logic. 

Analytics Enablement & Data Integrity 

• Partner closely with the People Analytics Manager to ensure HR systems are structured to support reliable reporting, meaningful analytics, and consistent data definitions. 

• Improve data integrity across systems by aligning field design, ownership, process inputs, and integrations to reduce discrepancies and improve trust in people data. 

• Ensure systems are built with analytics needs in mind, and conversely, help refine systems based on reporting and data-quality insights. 

• Support the broader HR function in strengthening compliance intelligence, scalable service delivery, and experience optimization through better system design and cleaner data. 

Cross-Functional Partnership & Change Enablement 

• Build strong working relationships across HR, IT, Payroll, Finance, Legal, and other G&A partners to align systems strategy and operational delivery with business needs. 

• Support change enablement through documentation, process clarity, and partnership with HR Operations and other HR team members; formal training delivery is not a core responsibility, but this role will help ensure systems and documentation are set up for successful adoption. 

• Contribute to future-state HR tech strategy, including evaluation of system opportunities and support for upcoming initiatives. 

What Success Looks Like 

• HRIS and the broader HR systems landscape are well-governed, well-documented, and operationally effective. 

• Core employee lifecycle processes are increasingly system-enabled, scalable, and aligned across HR and cross-functional partners. 

• Permissions, controls, and integrations support stronger compliance execution and audit readiness. 

• HR data is consistent, reliable, and usable across all company systems and platforms. 

• The HR team and business partners experience smoother workflows, less manual work, and clearer operational processes. 

• Flagship’s HR tech ecosystem is positioned for future growth, automation, and stronger decision support. 

Qualifications 

• Strong hands-on experience with enterprise HRIS administration and configuration; UKG experience strongly preferred, though deep equivalent HRIS experience may be considered. 

• Experience owning or supporting enterprise HR systems across multiple HR process areas. 

• Experience designing, managing, or supporting integrations between HRIS, ATS, payroll, and other people systems. 

• Strong understanding of how systems support employee lifecycle operations, compliance controls, and scalable service delivery. 

• Experience partnering closely with Enterprise Applications / IT teams on technical requirements, integrations, permissions, and implementation planning. 

• Strong judgment and ability to manage confidential employee and organizational data responsibly. 

• Strong written documentation and process-design skills. 

• Proven track record of independently driving operational improvements and cross-functional initiatives. 

At Flagship, we recognize there is no perfect candidate. If you have some of the experience listed above but not all, please apply anyway. Experience comes in many forms, skills are transferable, and passion goes a long way. We are dedicated to building diverse and inclusive teams and look forward to learning more about your unique background.

Recruitment & Staffing Agencies:  Flagship Pioneering and its affiliated Flagship Lab companies (collectively, “FSP”) do not accept unsolicited resumes from any source other than candidates.  The submission of unsolicited resumes by recruitment or staffing agencies to FSP or its employees is strictly prohibited unless contacted directly by Flagship Pioneering’s internal Talent Acquisition team.   Any resume submitted by an agency in the absence of a signed agreement will automatically become the property of FSP, and FSP will not owe any referral or other fees with respect thereto.

#LI-NM1

The salary range for this role is $128,000 - $176,000. Compensation for the role will depend on a number of factors, including a candidate’s qualifications, skills, competencies, and experience. Flagship Pioneering currently offers healthcare coverage, annual incentive program, retirement benefits and a broad range of other benefits. Compensation and benefits information is based on Flagship Pioneering's good faith estimate as of the date of publication and may be modified in the future.

The Role:

Reporting to the Associate Director, Clinical Operations, the Sr. Manager, Clinical Operations will ensure excellence in clinical trial planning, execution, and data collection, in accordance with regulatory guidelines. You will be working on a clinical study with responsibilities including site selection, contract negotiation, budget management, study start-up, conduct and close-out.  This role will collaborate with cross-functional study team as well as demonstrate excellent management of and partnership with CROs and vendors. The ideal candidate has a track record of executing complex, on-time clinical trials at a biotech/pharmaceutical company and delivering high quality clinical trial results.  

Responsibilities:

• Contribute to one or multiple clinical studies and demonstrate thorough knowledge of clinical operations project management. Collaborate with cross-functional clinical study team to support clinical study delivery.
• Evaluates, and ensures appropriate oversight of CROs and other external vendors.
• Ensure clinical trials are executed according to scope of work, budget, timelines, KPIs, and corporate goals.
• Establish and maintain effective communication and collaboration with functional area peers to meet clinical study objectives and support goals.
• Identify risks and propose solutions to facilitate clinical studies.
• Responsible for review and oversight of the study-level budget(s) and demonstrates accountability for the management of the budgets through managing the review and approval of contracts and/or work order changes; contribute to budget forecasting and accruals in collaboration with finance.
• Oversee and manage the creation, maintenance, QC and close out of TMF activities.
• Ensure appropriate oversight of enrollment, site activation and data collection milestones.
• Contribute to and support team to ensure the completeness of study documents including, study protocol, investigator brochure, informed consent forms, clinical study reports and case report forms.
• Collaborate with Data Management to ensure timely and efficient database lock. Participate in data review and reconciliation efforts.
• Lead or co-lead department initiatives to support an expanding organization.
• Travel may be required (10% – 15%).

Competencies Include:

• Detail and process orientated, with excellent project management skills, including risk assessment and contingency planning.
• Excellent problem solving, communication and organization skills.
• Flexibility with changing priorities, ability to think critically, strong attention to detail, and ability to work well under pressure.
• Ability to work in a collaborative environment and build effective working relationships across the organization.
• Demonstrated leadership and ability to strategically plan, organize and manage multiple projects simultaneously.

 Qualifications:

• At least 5 - 7 years of Clinical Operations experience.
• Bachelor’s degree or higher in a scientific or healthcare discipline preferred and relevant experience within the biotech, pharmaceutical, or CRO industry.
• Extensive knowledge of current ICH-GCP guidelines.
• Relevant experience managing early through late Phase clinical trials.
• Demonstrated cross-functional leadership fostering team spirit and team motivation.
• Capability to challenge status-quo using risk management approach.
• Able to thrive in a remote/virtual environment.

Additional Information:

Nuvalent is committed to fair and equitable compensation practices, aiming to provide employees with competitive total rewards packages.

The targeted salary range below reflects what Nuvalent reasonably and in good faith expects to offer for this position at the time of posting, but the final salary determination may be within or outside this range based on various factors, including, but not limited to, experience, skills, education, and market factors.  The range will be reviewed regularly and is subject to change.

Nuvalent also offers a comprehensive benefit package to support our employees at each stage of their career, financial, health, and well-being journey, including medical, dental, and vision insurance, 401(k) retirement savings plan, generous paid time off (including a summer and winter company shutdown), and much more.

The Role:

Reporting to the Associate Director, Formulation Sciences, the Senior Manager, Formulation Sciences will act as late-stage drug product subject matter expert and will support drug product process validation toward commercialization. The successful candidate needs to demonstrate a proven record of working in a virtual environment with CDMOs to deliver clinical and commercial supplies in support of fast-paced late-stage development programs. Using strategic thinking, the Senior Manager must be able to develop and execute process validation strategies for successful product commercialization.

This individual has responsibility for support of drug product process validation, scale up, and post-approval changes (SUPAC) and routine commercial manufacturing activities across Nuvalent’s contract research and manufacturing organizations. The primary accountability is being the steward for product development and manufacturing as these programs transition through development and into commercialization. The ultimate goal will be to ensure robust process and manufacture strategies for consistent commercial supply.

Responsibilities:

• Support drug product Process Validation activities, Scale up and post-approval changes (SUPAC) and routine commercial manufacturing at CDMOs.
• Identify critical process parameters based on the risk assessment and understanding the impact of material attributes and process parameters on critical quality attributes. Implement appropriate process controls to ensure delivery of consistent batch product quality.
• Draft, coordinate, execute validation protocols, perform data analysis, author/review and approve process validation reports with consistent and effective communication with other functions.
• Provide support to routine process validation studies, assisting with product technology transfers or lifecycle management changes such as process improvement, addition of secondary API and manufacture site change etc.
• Perform technical review of drug product manufacture deviations, change controls, perform process monitoring (manufacturing data summary and analysis, data presentation), perform activities for drug product lot release (assess deviations and process changes).
• Work closely with other team members and cross-functionally with quality assurance, analytical/QC, chemical development, supply chain, and project management team to achieve all project deliverables.
• Provide support for technical decision-making regarding cGMP compliance, validation strategy and regulatory pathway for SUPAC changes etc.
• Familiar with statistical analysis software, such as JMP.
• Perform process capability analysis, identify risk, and make recommendations for process improvement.
• Manage documentation, change controls, material inventory, product complaints, and deviation resolution at CDMOs.
• Represent the drug product group as a Subject Matter Expert to support audits and regulatory inspections.

• Support authoring the relevant technical sections of regulatory filings.

• Support late-stage validation and post-approval readiness activities and commercial manufacture activities within a virtual working environment.

Competencies:

• Strong organizational, planning, and multitasking skills in a fast‑paced environment.
• Excellent relationship‑building and communication skills across diverse teams.
• Evidence of effective cross‑functional collaboration with both internal teams and external partners.
• Strong problem‑solving and analytical skills with the ability to break down complex issues.
• Results‑driven mindset with attention to quality and timelines. A strong understanding and knowledge of cGMP/ICH regulations and an ability to apply them to drug product development and manufacturing is required.
• Excellent organization and multi-tasking skills.
• Experience building positive and effective cross functional relationships and the ability to align stakeholders, both internally and externally to Nuvalent.

 Qualifications:

• PhD in pharmaceutics, pharmaceutical sciences, chemical engineering or related field with a minimum of 3+ years or MS with 6+ years /BS with 10+ years of industry experience.
• Proven track record on drug product process validation, scale up and manufacture for solid dosage form (tablets).
• Experience with QbD principles and DOE methodology preferred.
• Manage the outsourcing manufacturing activities at CDMO sites to meet CMC goals.
• Understanding of cGMP/ICH guidelines and the ability to apply them to development and manufacturing.

• Experience with solid dosage form (tablet) process development; exposure to late-stage validation is a plus.

• Ability to author and critically review relevant development reports as well as regulatory dossiers.
• Up to 25% travel is expected, both domestically and internationally.

Additional Information:

Nuvalent is committed to fair and equitable compensation practices, aiming to provide employees with competitive total rewards packages.

The targeted salary range reflects what Nuvalent reasonably and in good faith expects to offer for this position at the time of posting, but the final salary determination may be within or outside this range based on various factors, including, but not limited to, experience, skills, education, and market factors.  The range will be reviewed regularly and is subject to change.

Nuvalent also offers a comprehensive benefit package to support our employees at each stage of their career, financial, health, and well-being journey, including medical, dental, and vision insurance, 401(k) retirement savings plan, generous paid time off (including a summer and winter company shutdown), and much more.