Position: Lab Manager 

Position Type: Full time, permanent 

Department: Research and Development 

Location: Saltriver, Cape Town (onsite) 

Experience: BSc or MSc in Microbiology, Biochemistry, or a related field, with 5+ years of experience working in a similar role.  

Watchmaker Genomics is a global life science company based in Boulder, Colorado with an R&D and Production facility in Cape Town, South Africa. Our team is passionate about innovation and values collaboration, creativity, and scientific rigor. We believe that the intersection of biology, engineering, and computer science presents exciting opportunities for developing novel technologies that promote research and improve human health. Watchmaker Genomics specializes in the design, development, and production of DNA- and RNA-modifying enzymes that enable high-growth applications in genomics, molecular diagnostics, and personalized medicine.

Position Description:

Watchmaker is inviting applications for the full-time position of Lab Manager based In Cape Town, South Africa. 

The successful candidate will thrive in a dynamic, fast-paced working environment and contribute directly to our company culture and success. This position reports to the Senior R&D Lab Manager and provides an opportunity to ensure that the R&D laboratory runs efficiently and safely.

Responsibilities

• General lab organization, space, and resource allocation
• Own and maintain organized, up-to-date R&D inventories - including fridge and freezer stock, chemicals, reagents, and other lab consumables
•  Monitor usage of routine consumables, chemicals and reagents, and raise procurement requisitions to help avoid delays to critical projects.
• Support procurement of specialized and general lab equipment and instruments
• Support receiving of incoming orders and ensure they are accurately logged against procurement records
• Manage the maintenance and calibration of lab equipment and instruments, including keeping equipment clean and ensuring maintenance schedules and best practices are followed
• Document and manage Standard Operating Procedures (SOPs) where appropriate to ensure that routine procedures, assays and experiments are performed reliably
• Ensure good Safety, Health and Environment (SHE) practices, including waste disposal
• Provide regular training on SOPs, equipment usage, SHE compliance, etc.
• Manage general lab cleaning, glassware reprocessing (washing, autoclaving and drying), etc.
• Preparation of standard solutions, reagents, agar plates, etc.
• Optionally, carry out routine lab procedures and/or research
• Carry out other ad hoc tasks as required

Skills and Requirements

The following skills and experience are requirements for the position:

• Strong organizational skills, with the ability to plan analytically, logically, and practically
• Excellent computer literacy including applications skills, especially with spreadsheets
• Excellent communication and interpersonal skills
• Experience with procurement management systems, ERP systems, and/or accounting systems will be an advantage
• A good knowledge of local vendors of laboratory equipment, consumables, chemicals, and reagents etc. will be an advantage
• Experience with automated liquid handling systems, NGS sequencing platforms, or other specialist protein or genomics technologies will be an advantage

A proven track record of laboratory management and/or a strong willingness to learn the role is important. 

Education

BSc or MSc in Microbiology, Biochemistry, or a related field, with a 5+ years of experience working in a similar role.  Remuneration will be commensurate with experience and skills.

Personal Attributes 

• Proactive, structured, and highly reliable 
• Comfortable operating with autonomy and accountability 
• Able to work effectively across disciplines and seniority levels 
• Practical, solutions‑oriented, and calm under pressure
• Meticulous and detail-orientated 

Application Requirements 

To apply for the position, please submit the following in a PDF format on watchmakergenomics.com: 

• Letter of motivation (upload where it says cover letter)
• Resume or Curriculum vitae, highlighting relevant qualifications and experience

Applications without a Letter of Motivation will not be considered. Applicants must be South African or be eligible to work in South Africa and already possess the necessary work permits or visas, or be able to obtain them before responding to this vacancy.

To ensure your application is considered, please submit it by 23 October 2026. Please note that this position may close earlier if we receive a high volume of applications. We encourage you to apply as soon as possible.

If selected to participate in the interview process, the names and contact information of three professional references who are able to assess your suitability for the position in terms of the specified requirements will be requested. We will also request a current pay slip.

NO RECRUITMENT AGENCIES PLEASE

We are only accepting direct applications for this position. We are not working with external recruiters or agencies at this time. Unsolicited resumes or candidate submissions from third-party recruiters will not be considered and will be deemed the property of Watchmaker Genomics

SOUTH AFRICA - WE ARE AN EQUAL OPPORTUNITY/AFFIRMATIVE ACTION EMPLOYER

Watchmaker Genomics is committed to being an equal opportunity employer and creating a culturally diverse environment. All qualified applicants will receive consideration for employment without regard to race, color, religion, gender, gender identity or expression, sexual orientation, national origin, genetics, disability status, age, or veteran status or any other characteristics as protected by applicable law.

All applicants will be asked if they are currently eligible to work in South Africa.  South African citizens are preferred.

This position may be subject to pre-employment checks, including driving history check, drug screening and a background check for any convictions directly related to its duties and responsibilities. All pre-employment checks will comply with all applicable laws.