Cambridge Mobile Telematics (CMT) is the world’s largest telematics service provider. Its mission is to make the world’s roads and drivers safer. The company’s AI-driven platform, DriveWell® Fusion, gathers sensor data from millions of IoT devices — including smartphones, proprietary Tags, connected vehicles, dashcams, and third-party devices — and fuses them with contextual data to create a unified view of vehicle and driver behavior. Auto insurers, automakers, commercial mobility companies, and the public sector use insights from CMT’s platform to power risk assessment, safety, claims, and driver improvement programs. Headquartered in Cambridge, MA, with offices in Budapest, Chennai, Seattle, Tokyo, and Zagreb, CMT measures and protects tens of millions of drivers across the world every day.

CMT is looking for a creative, collaborative, and highly motivated Machine Learning Intern to help develop applied machine learning capabilities using real-world mobility and behavioral data. This internship is ideal for someone who enjoys solving ambiguous problems, building practical ML workflows, working with messy real-world datasets, and translating technical findings into clear recommendations.

The intern will work on a 12-week applied ML project involving data exploration, labeling strategy, feature engineering, model development, evaluation, and stakeholder-facing analysis. The ideal candidate has strong Python skills, a solid foundation in machine learning, strong initiative, and the ability to make progress in open-ended problem spaces.

Responsibilities:

• Explore real-world mobility datasets and identify useful behavioral, temporal, contextual, and aggregate patterns
• Help define practical data labeling guidelines, quality criteria, and edge-case handling rules
• Build and validate datasets for supervised machine learning experiments
• Develop baseline and improved ML models using Python and standard data science workflows
• Perform feature engineering, model evaluation, error analysis, and iteration
• Assess model performance across relevant data segments and edge cases
• Summarize findings, limitations, risks, and opportunities for technical and product stakeholders
• Produce clear documentation, analysis reports, and final recommendations

Qualifications:

• Currently pursuing a Bachelor’s, Master’s, or PhD degree in Computer Science, Data Science, Machine Learning, Statistics, Engineering, Applied Math, or a related quantitative field
• Strong Python programming skills and comfort working with real-world datasets
• Solid understanding of supervised machine learning, feature engineering, classification metrics, train/test splits, and error analysis
• Experience with common Python data science libraries such as pandas, NumPy, scikit-learn, PyTorch, TensorFlow, or similar tools
• Strong analytical and problem-solving skills, with a bias toward initiative and ownership
• Clear written and verbal communication skills, including the ability to explain technical findings to non-technical stakeholders

Compensation and Benefits:

• Fair and competitive hourly rate based on education level
• Flexible scheduling options depending on role and responsibilities

Additional Perks:

• Feel great working to improve road safety around the world!
• Join one of our many employee resource groups including Black, AAPI, LGBTQIA+, Women, Book Club and Health & Wellness
• CMT will do all that is possible to support our employees and create a positive and inclusive work environment for all!

Commitment to Diversity and Inclusion:

At CMT, we believe the best ideas come from a mix of backgrounds and perspectives. 

We are an equal-opportunity employer committed to creating a workplace and culture where everyone feels valued, respected, and empowered to bring their unique talents and perspectives. Diversity is essential to our success, and we actively seek candidates from all backgrounds to join our growing team. 

We do not discriminate based on race, religion, color, national origin, gender, sexual orientation, age, marital status, veteran status or disability state. CMT is headquartered in Cambridge, MA. To learn more, visit www.cmtelematics.com and follow us on X @cmtelematics.

Why Join Us?

As a member of the Parabilis Medicines team, you will be a part of an organization dedicated to creating extraordinary medicines for diseases with urgent unmet needs, harnessing our proprietary peptide platform to transform treatment possibilities for patients. Parabilis is a clinical-stage biopharmaceutical company dedicated to unlocking high-impact protein targets long-considered undruggable. The company has developed a new class of stabilized, cell-penetrant alpha-helical peptides – Helicons™ – capable of modulating intracellular proteins that are inaccessible to traditional drug modalities.

Headquartered in Cambridge, Mass., Parabilis is advancing a focused pipeline of multiple first-in-class therapies across both rare and common cancers. Its lead asset, zolucatetide (FOG-001), is a first-in-class, clinically validated direct inhibitor of the interaction between β-catenin and the T-cell factor (TCF) family of transcription factors, implicated in millions of cancer cases annually, including in colorectal cancer, desmoid tumors, hepatocellular carcinoma and a range of other Wnt/β-catenin-driven tumors. In Phase 1 clinical trials, zolucatetide produced the first-ever clinical evidence that it can directly inhibit this interaction, once previously considered “undruggable” despite its role across multiple cancer types. Parabilis is also advancing investigational degraders of ERG and ARON into clinical development for the treatment of prostate cancer, as well as progressing other preclinical programs. Backed by a recent $305 million Series F financing, Parabilis is entering an exciting phase of growth and execution.

What’s the opportunity?

The VP, Development Data Science will build and lead a cross functional data centric matrix to accelerate drug development, support regulatory submissions and guide the Real-World Data (RWD) / Real-World Evidence (RWE) function at Parabilis. This role is responsible for end-to-end strategy and execution of RWD/RWE and clinical data science to inform trial design, contextualize clinical results, support biomarker and translational work, and optimize site and patient selection.

The VP will partner closely with Clinical Development, Clinical Operations, Biostatistics, Translational/Computational Biology, Regulatory, and the broader Data Science & Engineering team to maximize the probability of success of our clinical programs.

• Strategy & Leadership
  • Define and own the Clinical Data Science strategy.
  • Serve as the senior Clinical Data Science leader and primary point of contact for RWD/RWE across programs aligned with portfolio and corporate objectives.
  • Represent Clinical Data Science on cross-functional governance and portfolio forums.
• RWD/RWE & Clinical Analytics
  • Design and oversee RWE studies to contextualize clinical trials, including synthetic/external control arms, patient matching, and trial emulation.
  • Use RWD to inform clinical trial design (eligibility criteria, endpoints, enrichment strategies), dose/regimen selection, and go/no-go decisions.
  • Contribute data science insights for feasibility and site selection, including epidemiology, patient journeys, referral patterns, and diversity/access.
  • Integrate RWD with internal clinical and biomarker data to support forward and reverse translation, target and indication strategy, and mechanism-of-resistance analyses.
  • Establish and maintain best practices in causal inference, comparative effectiveness, and time-to-event modeling relevant to RWE in oncology.
• Data Assets, Partnerships & Infrastructure
  • Identify, evaluate, and prioritize RWD sources (EHR, claims, registries, genomic/omic datasets, imaging, PROs) to support current and future clinical needs.
  • Lead collaboration and contracting with RWD providers and academic/industry partners in coordination with Commercial, Business Development, Legal, and Procurement.
  • Partner with Engineering and Data Science to define requirements for secure, scalable, compliant RWD infrastructure and analytic environments.
  • Ensure data quality, interoperability, and governance suitable for regulatory-grade analyses.
• Team Building & Management
  • Build and lead a high-performing Clinical Data Science team (e.g., RWE epidemiologists, clinical data scientists, etc).
  • Set clear objectives, provide regular feedback, and support growth and succession planning.
  • Foster a culture of scientific rigor, transparency, and effective collaboration with Clinical Development, Biostatistics, and other partners.
• Cross-Functional Collaboration & Communication
  • Work in an integrated way with Clinical and Development teams to define key questions and translate them into analytic and RWE plans.
  • Communicate complex methods, assumptions, and results clearly to clinical, technical, and executive stakeholders.
  • Support regulatory and payer/Health Technology Assessment interactions where RWE and clinical analytics contribute to program strategy (e.g., briefing documents, responses, meeting preparation).
  • Collaborate with Translational and Computational Biology to align biomarker and patient selection strategies with integrated clinical and RWD analytics.
• Governance, Quality & Compliance
  • Ensure RWD/RWE activities meet regulatory, ethical, and privacy standards (e.g., GCP, data de-identification and privacy requirements).
  • Implement documentation, reproducibility, and quality standards for Clinical Data Science analyses.
  • Monitor evolving external expectations for use of RWE in regulatory and payer settings and adapt internal practices accordingly.

What you’ll need to be successful:

• PhD, MD, PharmD, or MS in Epidemiology, Biostatistics, HEOR, Data Science, or a related quantitative field.
• 12–15+ years of experience in pharma/biotech, healthcare technology, or related sectors, with significant focus on RWD/RWE and clinical development; oncology experience strongly preferred.
• Proven track record designing and delivering impactful RWE studies to inform clinical, regulatory, or payer decision-making.
• Strong understanding of clinical trial design, biostatistics fundamentals, and translational/biomarker concepts, ideally in oncology or immuno-oncology.
• Demonstrated experience building, leading, and developing high-performing quantitative teams in a matrixed environment.
• Hands-on familiarity with major RWD types (EHR, claims, registries, genomic/omic datasets) and key vendors/platforms.
• Proficiency with modern analytic tools and programming environments (e.g., R, Python, SQL) and with guiding development of robust, reproducible analytic workflows.
• Excellent communication and influencing skills with the ability to engage effectively with clinicians, statisticians, senior leaders, and external partners.

Core Values

Parabilis Medicines is a team of passionate pioneers who are trailblazing the future of precision medicine with the aim of making a meaningful difference in the lives of patients. The company is committed to promoting an inspiring and flourishing working environment for all employees across the business, in all departments, and driving innovation for patient benefit.

• Growth-Minded. We’re inventing a new class of medicines—one applicable to therapeutic targets that have been dreamt about, but always considered impossible to drug. Our work requires us to be curious, humble and adaptable.
• In(ter)dependent. We are fiercely independent as a leader in defying the limitations of current therapeutic modalities, and interdependent as a team as we work collaboratively to shift drug discovery paradigms and provide patients with better treatment options.
• Patient-focused. We are deeply focused on patient outcomes, and all energy in the company is focused on science as it translates to patient impact.
• All-In. We’re All-In on solving some of the hardest scientific challenges and delivering one of the most effective new classes of drugs in history.

The base salary range for this position is $325,000-$380,000 per year, depending on experience, qualifications, and internal practices. Parabilis’s total compensation package also includes an annual target bonus, equity, and a comprehensive suite of competitive benefits designed to support our employees’ overall well-being.

As an equal opportunity employer, Parabilis Medicines values an inclusive workplace and welcomes applicants of all backgrounds and experiences. All qualified applicants will receive consideration for employment without discrimination on the basis of race, color, religion, sex, sexual orientation, gender identity, national origin, protected veteran status, disability, or any other factors prohibited by law.

30 Acorn Park Drive    |     Cambridge, MA 02140    |    www.parabilismed.com

The Opportunity

This Real World Evidence (RWE)/Health Economics (HEOR) Contractor role supports the RWE/HEOR Senior Director in leading RWE execution for pipeline assets. The role is fun and flexible with a mix of both study execution and data analytics. This person will be accountable for developing and delivering components of the evidence generation plan (including RWE and economic value evidence), and driving high-quality deliverables that inform internal decision-making during product development, pre-launch readiness, and lifecycle planning. The role is anchored to 1–2 priority pipeline assets/indications.

This is a remote role based with flexible hours. We are currently seeking an individual with 20-30 hours of weekly availability with potential to increase hours in late 2026/2027.

Responsibilities

• Evidence strategy and planning: Maintain US RWE & HEOR plans for 1–2 priority pipeline assets/indications, aligned to US medical, payer, and access needs; translate strategy into actionable workplans, timelines, and resourcing proposals.
• Study leadership (RWE/HEOR): Own day-to-day leadership for assigned real-world evidence and health outcomes studies (e.g., real-world evidence studies, cost-effectiveness/budget impact analyses, burden of illness, treatment patterns, patient-focused outcomes) including design and execution in partnership with internal functions and external vendors.
• Scientific communication and quality: Draft/review project specifications, protocols, statistical analysis plans, study reports, abstracts, posters, and manuscripts; ensure adherence to SOPs and high scientific/operational quality.
• Analytic execution and statistics: Execute ad hoc analyses in clinical trial, claims and PCOR data as needed for ad hoc and protocol/SAP driven analyses. This may include feasibility or full protocol execution.
• Governance, compliance, and capability building: Complete required training, adhere to company/department SOPs, and contribute to continuous improvement of processes that enable efficient planning, execution, and dissemination of RWE & HEOR deliverables.

Required Qualifications

• Master’s degree or PhD in epidemiology, health economics and outcomes research, public health, biostatistics, or related discipline.
• At least 1+ years of experience in the pharmaceutical industry and/or managed care, hospital, academic, or healthcare consulting environment with exposure to HEOR/RWE strategy and application
• Proficiency with SAS and/or R for statistical programming. Preference for experience in clinical trials OR claims data.
• Expertise in RWE and study designs/methods evidenced by publications and/or contributing to study concept sheets and protocols, reviewing/authoring key sections of statistical analysis plans and study reports, and ensuring publication/disclosure readiness in accordance with ICJME criteria
• Strong communication and presentation skills, demonstrated by developing and presenting clear, decision-oriented materials (e.g., evidence strategy slides, executive readouts) and summarizing outcomes/next steps for senior audiences

Preferred Qualifications

• Demonstrated success developing and executing health outcomes research plans and delivering high-quality data generation outputs.
• Experience managing real-world data sources and vendors (e.g., claims, EHR, registries) and translating findings into actionable insights and value messages.
• Demonstrated ability to influence without authority in a matrix environment, evidenced by aligning cross-functional stakeholders on objectives/trade-offs, documenting decisions, and driving actions to closure.
• Experience in PCOR implementation and validation

Work Location and Condition

• At Amylyx, we proudly support remote work opportunities within the United States. However, due to business considerations related to health insurance coverage and state tax regulations, we are unable to hire employees who reside and/or work in certain states. Currently, we are not considering applicants from Alaska, Arizona, Hawaii, Michigan and Tennessee.
• You must have access to work in setting that meets all requirements of the role (including privacy, reliable internet access, phone, ability to communication via video conference, etc.) at your remote location

Position Summary:

The Senior Director, Commercial Strategy lead is responsible for understanding the evolving needs of the Stargardt community and shaping the brand strategy, including the execution of comprehensive marketing plans. This role will lead brand planning, product launches, and lifecycle management, working closely with cross-functional teams across commercial, medical, regulatory, and clinical functions.

This is a leadership role on the commercial team that will own the go-to-market strategy, lifecycle planning, ensuring seamless collaboration across functions and support market access research ultimately driving meaningful patient impact and delivering strong business results.

Primary Responsibilities:

Brand Strategy & Tactical Execution:

• Develop integrated brand strategies and lifecycle activities to support differentiation and commercialization goals
• Drive disease area strategy, market segmentation, and product positioning based on unmet needs, competitive landscape, and evolving science
• Responsible for creating external (promotional/educational) communication materials for external use with customers (ECPs and Patients)
• Partner with Corporate Communications to support development of the Corp Communications tactics and messages as needed
• Lead the cross-functional workshops for the development of strategic and tactical plans for gildeuretinol

Competitive Strategy and Response:

• Assess emerging trends, market dynamics, and competitive activity to inform commercial decisions
• Lead competitive scenario planning and collaborate with medical, corp. comms, strategic planning and clinical to develop competitive response strategy
• Translate scientific and market insights from ECPs and patients (through market research, ad boards, etc.) into differentiated product strategy and value stories
• Evaluate strategic implications of evolving regulatory, pricing, and access landscapes globally
• Provide input into forecasting assumptions and evaluate ROI for activities
• Collaborate closely with regulatory, medical affairs, market access and corporate communications to ensure alignment of brand vision and execution

Program Team and key workstreams participation:

• Lead development/optimization of TPP
• Generate and communicate ECP/Patient insights to inform Program strategy
• Be the commercial voice on program team and inform decisions impacting commercialization
• Participate in the evidence generation, pubs planning and LCM strategy sub teams to represent the commercial POV

Qualifications:

• Education and Certification
• Advanced degree (MBA) in marketing/ business, or scientific degree preferred
• Requires 12+ years of experience or the equivalent combination of education and experience

• Skills and Key Success Factors:
  • Entrepreneurship spirit with a passion to build, learn and evolve with the team
  • Highly organized and detail oriented with a passion to deliver quality results
  • Excellent verbal and written communication skills, with experience translating complex concepts for various audiences
  • Demonstrated record of intellectual curiosity, innovation and creative problem solving with an entrepreneurial spirit
  • Ability to lead fast-paced projects with a keen sense of urgency to get the job done well
  • Evidence of "hands-on" experience and expertise
  • Proven and successful track record as a team-player and collaborator in small working environments
  • Highest levels of professionalism, confidence, personal values and ethical standards

Other Relevant Information:

• Travel:  Able to travel up to 25% of time

Compensation

• Base Salary Range: $235K - $275K, with the actual contingent upon several factors such as the selected candidate’s education/work experience/training, and other factors (travel requirements, etc.)
• Discretionary Bonus: up to 25% of Base Salary, contingent upon meeting performance components
• Equity: initial grant of incentive stock options
• Benefits: Eligible to participate in group medical/dental/vision insurance plans; short- and long-term disability plans; life insurance; 401(K) plan; flexible time off policies and others. Eligibility and participation requirements vary by plan.

About the Role

We are seeking a Senior Commercial Program Manager to drive operational excellence across the Commercial organization. This role will focus on building scalable processes, improving cross-functional workflows, and ensuring consistent operating rhythms that enable the business to execute effectively against revenue goals.

The ideal candidate combines strong analytical thinking with pragmatic execution skills. They are highly organized, comfortable working across multiple stakeholders, and skilled at translating business priorities into structured processes, clear metrics, and efficient workflows to increase speed, predictability, and efficiency.

This individual will work closely with commercial leadership to run our operating cadences, eliminate friction across cross-functional workflows, and build the infrastructure that lets the business scale. 

Key Responsibilities

Process Design & Workflow Optimization

• Evaluate existing commercial workflows and identify opportunities to streamline processes and reduce friction in partnership with the Commercial team
• Design and implement scalable processes that improve efficiency
• Standardize documentation, handoffs, and communication channels to improve cross-functional alignment
• Reduce manual work and improve repeatability of core commercial processes

Metrics, Reporting & Insights

• Partner with Analytics  to define and maintain key commercial metrics
• Analyze performance trends to identify opportunities for improvement
• Ensure leadership has clear visibility into pipeline health, performance against goals, and operational risks
• Translate data into actionable insights that support decision-making

Cross-Functional Program Leadership

• Drive alignment across Commercial and Operations teams
• Support execution of key commercial initiatives and strategic priorities
• Ensure dependencies are clearly identified and managed
• Help teams stay organized and focused on delivering outcomes

Continuous Improvement

• Identify structural issues that slow execution or create ambiguity
• Proactively propose solutions that improve clarity, accountability, and speed
• Build frameworks that scale with company growth
• Serve as a thought partner to commercial leadership on operational improvements

Commercial Operating Rhythm

• Support the execution of cadences across the Commercial organization, including leadership meetings, quarterly planning, and goal tracking
• Ensure agendas, priorities, and action items are clearly defined and followed through
• Identify opportunities to improve meeting effectiveness and decision-making clarity
• Help leadership maintain focus on highest-impact initiatives

Qualifications

Required

• 6–10 years of experience in program management, business operations, strategy & operations, or commercial operations
• Demonstrated experience improving business processes and operational workflows
• Strong organizational skills and attention to detail
• Experience working with leadership teams to drive execution against strategic priorities
• Strong analytical skills and comfort working with metrics and dashboards
• Excellent communication skills, including ability to synthesize complex topics clearly
• Ability to influence without authority across multiple stakeholders
• Experience supporting structured operating cadences

Preferred

• Experience supporting Sales, Marketing, or Customer Success organizations
• Familiarity with CRM and analytics tools (e.g., Salesforce, HubSpot, Looker)
• Experience working in high-growth or scaling organizations

Position Overview

We are seeking a detail-oriented Director, Compliance to join Iterative Health's growing team in New York, NY or Cambridge, MA. This role will be instrumental in leading the strategic development of compliance programs to ensure our clinical trial optimization solutions meet all regulatory requirements across healthcare, clinical trials, and data privacy domains. The ideal candidate will have deep expertise in healthcare compliance frameworks and the ability to operationalize complex regulatory requirements in a fast-paced health tech environment.

Key Responsibilities

Regulatory Compliance & Risk Management

• Experienced with the compliance aspects of clinical trial & clinical research
• Maintain comprehensive compliance with GDPR, HIPAA, and other applicable data privacy regulations
• Lead SOC 2 Type II audit preparation and ongoing compliance, including controls documentation and evidence collection
• Develop and implement compliance policies and procedures specific to clinical trial technologies and healthcare AI solutions
• Ensure adherence to Anti-Kickback Statute, Stark Law, and PhRMA Code requirements in all business relationships
• Monitor evolving AI regulations and their impact on clinical trial optimization platforms

Quality Management & Documentation

• Oversee Quality Management System (QMS) in partnership with other team members, for maintenance and contractual compliance 
• Establish and maintain comprehensive record retention policies across clinical, regulatory, and business functions
• Manage document control processes for clinical protocols, compliance documentation, and regulatory correspondence
• Coordinate with clinical operations team to ensure GCP compliance in trial management and data collection

Contract & Vendor Compliance

• Review and negotiate compliance terms in customer agreements, vendor contracts, and clinical trial agreements
• Conduct vendor risk assessments and ongoing compliance monitoring for third-party service providers
• Ensure contract compliance with healthcare customer requirements, including BAAs and data processing agreements
• Support commercial team with compliance aspects of customer onboarding and due diligence processes

Training & Cross-Functional Support

• Develop and deliver compliance training programs for employees across all functions
• Serve as primary compliance liaison with external auditors, regulators, and certification bodies
• Collaborate with legal, clinical, and product teams on regulatory strategy and risk mitigation
• Maintain compliance calendar and ensure timely completion of regulatory filings and renewals

Required Qualifications

Education & Experience

• Bachelor’s degree in Life Sciences, Business, or a related field plus 8+ years of compliance experience in healthcare, biotech, or clinical research organizations; advanced degree preferred
• OR Juris Doctor (JD) or other advanced degree plus 5+ years of compliance experience in healthcare, biotech, or clinical research organizations
• Direct experience with clinical trial regulations and GCP requirements
• Proven track record managing compliance programs in regulated industries

Technical Expertise

• Employment law and HR compliance expertise, including workplace privacy, salary transparency, employee data protection, and regulatory training requirements
• Corporate governance and general business compliance including anti-corruption, export controls, and corporate record-keeping requirements
• Privacy program management across all business functions, including vendor privacy assessments and cross-border data transfer compliance
• Financial compliance awareness including regulatory reporting requirements
• Deep knowledge of GDPR and HIPAA requirements and implementation
• Hands-on experience with SOC 2 audits and information security compliance frameworks
• Familiarity with clinical research regulations (GCP, ICH guidelines, 21 CFR Part 11)
• Understanding of AI/ML regulatory landscape in healthcare and clinical trials

Core Competencies

• Strong analytical and problem-solving skills with ability to translate complex regulations into actionable policies
• Excellent written and verbal communication skills for regulatory correspondence and training delivery
• Project management experience with ability to manage multiple compliance initiatives simultaneously
• Detail-oriented approach with strong documentation and process improvement capabilities

Preferred Qualifications

• Professional certifications (CIPP, CISA, CCEP, CHRC, or similar compliance credentials)
• Experience with international regulations (EU Clinical Trials Regulation, other global markets)
• Background in clinical research or pharmaceutical compliance
• Familiarity with AI ethics and algorithmic bias considerations in healthcare
• Experience with healthcare technology or SaaS compliance programs

About the Role

The Regional Director is responsible for owning and optimizing site-level performance across a portfolio of GI-focused clinical research sites. This role ensures operational excellence by aligning teams around key performance goals, elevating site capabilities, and maintaining consistency in trial execution. As a strategic operations leader, the Regional Director plays a central role in connecting site level performance with broader business objectives.

Responsibilities

• Manages staff across multiple sites, ensuring execution is aligned with protocol, regulatory requirements, and IH standards.
• Owns overall performance of assigned sites, including enrollment, data quality, compliance, and team culture.
• Ensures sites are set up for success (i.e. staffed appropriately and equipped with the appropriate equipment and training) and makes recommendations to allocate resources based on business needs. 
• Builds strong relationships and collaborates with PIs to align their engagement with study goals and operational strategy.
• Influences study portfolio, optimizing for profitability and value to patients. 
• Identifies and manages issues, concerns and problems related to site performance.
• Leads and develops CRCs, and other site-based research staff through clear expectations, performance coaching, and team development.
• Serves as a visible, hands-on people manager who builds high-performing, accountable teams.
• Identifies levers to drive site level KPIs through monitoring KPIs and performance trends, escalating to appropriate parties. 
• Implements corrective actions or process improvements as needed.
• Serves as the primary operational liaison between site staff and central functions.
• Drives a culture of ownership, collaboration, and continuous improvement across all assigned sites.

What We’re Looking For

Required Qualifications

• Knowledgeable about the critical elements for success in clinical trials: Ability to review protocols, programs, and assess the success of a project.
• Ability to influence change management and model flexibility
• Problem-Solving Skills: Ability to identify problems, develop and implement solutions.
• Strategic Planning: Ability to plan for short, medium and long term success and make recommendations for growth
• Ability to use data as a tool, identify trends, and draw conclusions. 
• Project Management: Demonstrated ability to successfully manage people/projects.
• Proactive problem-solving abilities and follow-through.
• Practices professionalism and integrity in all actions. 
• Communication Skills: Excellent written and verbal communication skills. 
• Working knowledge of CTMS, eDC and other core research systems. 
• Ability to travel: Up to 30% travel to provide operational oversight, hold team meetings, and attend other professional meetings/conferences as needed.

Preferred Qualifications

• Experience in managing a large site network and demonstrated success in achieving targets and optimizing operations.
• Experience with gastroenterology and/or hepatology studies. 

What We Offer

• Medical, dental, and vision insurance
• Life and disability insurance
• Parental leave
• Stock options
• Flexible work hours
• Unlimited paid time off

We are seeking a strategic and data-driven People Business Partner role to partner closely with leaders across corporate functions and site-based operational teams in support of a high performing, highly distributed healthcare services organization. This role will act as a trusted advisor, aligning people strategies with business priorities to support growth, scalability, and performance across the organization. Operating in a high-growth, M&A driven environment, this role requires a strong balance of strategic thinking and hands-on execution. The People Business Partner will play a key role driving organizational effectiveness, enabling leadership and supporting change initiatives while fostering a high-performing, mission-driven culture. This individual must be comfortable pivoting between both a strategic and hands-on level of engagement, with a strong focus on change and performance management,
talent/leadership development, organizational design, employee relations and integration.

Key Responsibilities

Strategic Business Partnership
● Serve as a trusted advisor, coach and thought partner to department, team and operational leaders, providing guidance on organizational strategy, workforce planning, employee relations issues and talent implications of business decisions
● Translate business priorities into actionable HR strategies that drive growth, scalability, and operational excellence to enable a high performing and engaged workforce.
● Develop a deep understanding of IH business units, financial drivers, and market industry dynamics to proactively shape people initiatives that help transform the business as we grow and scale our infrastructure.
● Serve as a strategic liaison and advisor between the business and People Team Center of Excellence’s (COE) to align HR service delivery with business priorities
● Identify opportunities to implement data-informed people strategies that strengthen organizational health, culture and maturity while directly impacting leadership effectiveness and team performance
● Lead workforce planning with business partners, anticipating skills and capabilities needed to scale the organization beyond current state – develop plans in conjunction with TA to identify talent profiles and succession bench ready for promotion to increased level of scope and responsibility

Talent and Performance Management
● Drive talent and performance management processes that reinforce accountability, ownership and high standards of behaviors / values alignment to support our high-performance culture
● Partner with leaders on succession planning, leadership development, compensation strategies and retention initiatives across the enterprise
● Use data and insights to inform talent decisions and effectively balance business needs with employee advocacy
● Coach and develop leaders to engage, motivate and lead high performing teams, identifying least effective performance and partnering with team leaders to address performance issues early on.

Change Management and Culture
● Lead change management efforts across our growing and evolving teams/structures to support effective communication, accountability and alignment to our strategic priorities
● Champion a culture of innovation, collaboration, and continuous improvement aligned with Iterative Health’s mission
● Support leaders in navigating ambiguity and leading through transformational change as an organization, providing insights and serving as a “thought partner” on operational and people challenges that dynamic growth brings.

Employee Relations and Coaching
● Provide expert coaching on employee relations, leadership effectiveness, and team dynamics to enable a highly engaged, productive workforce while maintaining consistency and alignment to IH policies and procedures.
● Support positive culture building initiatives and drive employee engagement initiatives with team leaders to build highly engaged, motivated team members.
● Ensure compliance with employment laws and company policies – identify opportunities to improve, create and implement policies and procedures that balance business needs with operational realities M&A

HR Integration
● Partner with internal stakeholders including People COE’s on due diligence, integration planning, and execution as part of pre and post-acquisition integration process
● Support organizational design, talent assessment, and cultural integration efforts to ensure seamless onboarding of acquired entities and team members to IH
● Anticipate, identify and mitigate people-related risks associated with rapid growth and change, including supporting HR initiatives focused on harmonization of system, processes and policies across the growing enterprise.

HR Program Execution
● Partner with COE to deliver best-in-class HR transformational initiatives to support a growing and scaling workforce
● Own HR projects in support of strategic HR agenda focused on employee engagement, leadership development, performance management, and operationalizing best in class people initiatives and infrastructure that will attract, develop and retain talent.

Qualifications
● 7–10+ years of progressive HR experience, including working in a fast-scaling, high-growth, complex and ambiguous start-up environment
● Experience in healthcare, clinical research, medtech, life sciences, or related industries strongly preferred
● Experience supporting a highly distributed, growing multi-site location network both domestically and globally is strongly preferred
● Demonstrated experience across a wide range of HR functional domains
● Strong business acumen with the ability to link HR strategy to financial and operational outcomes
● Proven ability to communicate and influence senior leaders as well as operate as a strategic partner, understanding the operational and strategic priorities of the business and how people strategies can make an impact
● Experience in organizational design, change management, and talent strategy
● Data-driven, analytical mindset with comfort leveraging data and analytics to inform decisions
● Excellent communication, coaching, and stakeholder management skills
● Comfort navigating through ambiguity and managing multiple competing priorities
● A builder and inventor mindset – orientation towards thinking outside the box to pilot and test programs and initiatives to iterate before applying a one-size fits all approach.

COMPANY DESCRIPTION

Mirai Bio is a Flagship-backed, privately held biotechnology company on a mission to transform the current approach to information molecule therapeutics to unlock their full therapeutic potential. In recent years, we have begun to experience the power of information molecules in treating historically undruggable diseases and in designing therapies with unprecedented turnaround times. Mirai’s platform integrates nanoparticle development with world-class informatics technologies and a novel pipeline of experimentation and discovery to drive a new generation of highly effective, therapeutically relevant information molecule therapies. We are seeking collaborative, relentless problem solvers that share our passion for impact to join us!

THE ROLE

We are seeking a Senior Director / Vice President of Scientific Strategy & Research Enablement to help architect and scale the research engine that powers this platform. Reporting to the SVP/Head of Platform, this role will operate at the intersection of scientific strategy, platform development, and execution, ensuring that our research organization has the infrastructure, partnerships, and operational frameworks necessary to move rapidly from invention to discovery.

This individual will play a key role in shaping how our science is executed—designing the systems, workflows, and external collaborations that enable scientists to focus on innovation while accelerating the generation of high-quality data and platform insights.

The ideal candidate will combine a strong understanding of modern research environments with the ability to build scalable systems that increase scientific productivity and translate platform capabilities into impactful programs.  This is an individual contributor role that is part of extended Executive Leadership team, and with opportunities for growth.

KEY RESPONSIBILITIES

Scientific Strategy and Research Enablement

• Partner closely with the SVP/Head of Platform and scientific leaders to translate research strategy into an integrated framework for execution across internal teams and external collaborators.
• Design and implement the infrastructure that supports discovery, including research workflows, collaboration frameworks, and data systems that enable efficient experimentation and decision-making.
• Identify opportunities to increase research velocity and rigor by optimizing experimental pipelines, data generation, and knowledge flow across the organization.
• Lead initiatives that remove barriers to scientific progress and improve how the organization generates, integrates, and interprets experimental data.
• Help ensure the organization’s scientific output is communicated clearly and effectively to internal and external stakeholders.
• Collaborate with research, finance, and leadership teams to align resources with the highest-impact scientific opportunities.
• Establish mechanisms for tracking research progress, milestones, and data generation across internal and partnered programs.
• Contribute to building a culture of scientific rigor, transparency, and operational excellence within the research organization.

Platform Development and External Scientific Partnerships

• Develop and manage a network of external collaborators and technology providers that extend the capabilities of the platform.
• Continuously evaluate emerging technologies, experimental capabilities, and vendors that can expand the company’s research toolkit.
• Structure and oversee scientific collaborations and SOWs to ensure alignment on experimental design, data quality and deliverables.

PROFESSIONAL EXPERIENCE & QUALIFICATIONS

Required

• Bachelor’s degree in life sciences, biotechnology, or related field; PhD required
• 10+ years of experience in biotechnology or pharmaceutical R&D, with exposure to discovery-stage research environments.
• Demonstrated experience enabling or managing complex research programs, scientific collaborations, or research infrastructure.
• Strong understanding of laboratory research workflows and modern approaches to data generation and management.
• Exceptional communication skills and the ability to synthesize complex scientific concepts into clear strategic narratives.

Preferred

• Experience in early-stage or venture-backed biotechnology companies.
• Familiarity with in vivo delivery technologies, genetic medicines, or nucleic acid therapeutics.

ABOUT FLAGSHIP PIONEERING:

Flagship Pioneering invents and builds platform companies, each with the potential for multiple products that transform human health, sustainability and beyond. Since its launch in 2000, Flagship has originated more than 100 companies. Many of these companies have addressed humanity’s most urgent challenges: vaccinating billions of people against COVID-19, curing intractable diseases, improving human health, preempting illness, and feeding the world by improving the resiliency and sustainability of agriculture.  

Flagship has been recognized twice on FORTUNE’s “Change the World” list, an annual ranking of companies that have made a positive social and environmental impact through activities that are part of their core business strategies and has been twice named to Fast Company’s annual list of the World’s Most Innovative Companies. Learn more about Flagship at www.flagshippioneering.com.

At Flagship, we accept impossible missions to enable bigger leaps. Our core values guide us through uncertainty and toward lasting impact.

We are an equal opportunity employer. All qualified applicants will be considered for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, disability, protected veteran status, or any other characteristic protected by law.

We recognize that great candidates often bring unique strengths without fulfilling every qualification. If you have some of the experience listed above but not all, please apply anyway. We are dedicated to building diverse and inclusive teams and look forward to learning more about your background and interest in Flagship.

Recruitment & Staffing Agencies: Flagship Pioneering and its affiliated Flagship Lab companies (collectively, “FSP”) do not accept unsolicited resumes from any source other than candidates. The submission of unsolicited resumes by recruitment or staffing agencies to FSP or its employees is strictly prohibited unless contacted directly by Flagship Pioneering’s internal Talent Acquisition team. Any resume submitted by an agency in the absence of a signed agreement will automatically become the property of FSP, and FSP will not owe any referral or other fees with respect thereto.

#LI-TL1

The salary range for this role is $275,000 - $340,000. Compensation for the role will depend on a number of factors, including a candidate’s qualifications, skills, competencies, and experience. Mirai Bio currently offers healthcare coverage, annual incentive program, retirement benefits and a broad range of other benefits. Compensation and benefits information is based on Mirai Bio's good faith estimate as of the date of publication and may be modified in the future.

COMPANY DESCRIPTION

Mirai Bio is a Flagship-backed, privately held biotechnology company on a mission to transform the current approach to information molecule therapeutics to unlock their full therapeutic potential. In recent years, we have begun to experience the power of information molecules in treating historically undruggable diseases and in designing therapies with unprecedented turnaround times. Mirai’s platform integrates nanoparticle development with world-class informatics technologies and a novel pipeline of experimentation and discovery to drive a new generation of highly effective, therapeutically relevant information molecule therapies. We are seeking collaborative, relentless problem solvers that share our passion for impact to join us!

THE ROLE

We are seeking a Senior Director / Vice President of Scientific Strategy & Research Enablement to help architect and scale the research engine that powers this platform. Reporting to the SVP/Head of Platform, this role will operate at the intersection of scientific strategy, platform development, and execution, ensuring that our research organization has the infrastructure, partnerships, and operational frameworks necessary to move rapidly from invention to discovery.

This individual will play a key role in shaping how our science is executed—designing the systems, workflows, and external collaborations that enable scientists to focus on innovation while accelerating the generation of high-quality data and platform insights.

The ideal candidate will combine a strong understanding of modern research environments with the ability to build scalable systems that increase scientific productivity and translate platform capabilities into impactful programs.  This is an individual contributor role that is part of extended Executive Leadership team, and with opportunities for growth.

KEY RESPONSIBILITIES

Scientific Strategy and Research Enablement

• Partner closely with the SVP/Head of Platform and scientific leaders to translate research strategy into an integrated framework for execution across internal teams and external collaborators.
• Design and implement the infrastructure that supports discovery, including research workflows, collaboration frameworks, and data systems that enable efficient experimentation and decision-making.
• Identify opportunities to increase research velocity and rigor by optimizing experimental pipelines, data generation, and knowledge flow across the organization.
• Lead initiatives that remove barriers to scientific progress and improve how the organization generates, integrates, and interprets experimental data.
• Help ensure the organization’s scientific output is communicated clearly and effectively to internal and external stakeholders.
• Collaborate with research, finance, and leadership teams to align resources with the highest-impact scientific opportunities.
• Establish mechanisms for tracking research progress, milestones, and data generation across internal and partnered programs.
• Contribute to building a culture of scientific rigor, transparency, and operational excellence within the research organization.

Platform Development and External Scientific Partnerships

• Develop and manage a network of external collaborators and technology providers that extend the capabilities of the platform.
• Continuously evaluate emerging technologies, experimental capabilities, and vendors that can expand the company’s research toolkit.
• Structure and oversee scientific collaborations and SOWs to ensure alignment on experimental design, data quality and deliverables.

PROFESSIONAL EXPERIENCE & QUALIFICATIONS

Required

• Bachelor’s degree in life sciences, biotechnology, or related field; PhD required
• 10+ years of experience in biotechnology or pharmaceutical R&D, with exposure to discovery-stage research environments.
• Demonstrated experience enabling or managing complex research programs, scientific collaborations, or research infrastructure.
• Strong understanding of laboratory research workflows and modern approaches to data generation and management.
• Exceptional communication skills and the ability to synthesize complex scientific concepts into clear strategic narratives.

Preferred

• Experience in early-stage or venture-backed biotechnology companies.
• Familiarity with in vivo delivery technologies, genetic medicines, or nucleic acid therapeutics.

ABOUT FLAGSHIP PIONEERING:

Flagship Pioneering invents and builds platform companies, each with the potential for multiple products that transform human health, sustainability and beyond. Since its launch in 2000, Flagship has originated more than 100 companies. Many of these companies have addressed humanity’s most urgent challenges: vaccinating billions of people against COVID-19, curing intractable diseases, improving human health, preempting illness, and feeding the world by improving the resiliency and sustainability of agriculture.  

Flagship has been recognized twice on FORTUNE’s “Change the World” list, an annual ranking of companies that have made a positive social and environmental impact through activities that are part of their core business strategies and has been twice named to Fast Company’s annual list of the World’s Most Innovative Companies. Learn more about Flagship at www.flagshippioneering.com.

At Flagship, we accept impossible missions to enable bigger leaps. Our core values guide us through uncertainty and toward lasting impact.

We are an equal opportunity employer. All qualified applicants will be considered for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, disability, protected veteran status, or any other characteristic protected by law.

We recognize that great candidates often bring unique strengths without fulfilling every qualification. If you have some of the experience listed above but not all, please apply anyway. We are dedicated to building diverse and inclusive teams and look forward to learning more about your background and interest in Flagship.

Recruitment & Staffing Agencies: Flagship Pioneering and its affiliated Flagship Lab companies (collectively, “FSP”) do not accept unsolicited resumes from any source other than candidates. The submission of unsolicited resumes by recruitment or staffing agencies to FSP or its employees is strictly prohibited unless contacted directly by Flagship Pioneering’s internal Talent Acquisition team. Any resume submitted by an agency in the absence of a signed agreement will automatically become the property of FSP, and FSP will not owe any referral or other fees with respect thereto.

#LI-TL1

The salary range for this role is $275,000 - $340,000. Compensation for the role will depend on a number of factors, including a candidate’s qualifications, skills, competencies, and experience. Mirai Bio currently offers healthcare coverage, annual incentive program, retirement benefits and a broad range of other benefits. Compensation and benefits information is based on Mirai Bio's good faith estimate as of the date of publication and may be modified in the future.

The Position

Reporting to our Co-CEO’s, the SVP of Program Leadership & Development will drive the advancement of our clinical-stage pipeline. This individual will be responsible for end-to-end leadership of one or more key development programs translating scientific innovation into clinical, regulatory, and commercial success.

The SVP of Program Leadership & Development will play a critical role in shaping program strategy, guiding cross-functional execution, and maximizing asset value from early development through late-stage trials and potential regulatory approval.

This role will serve as a core member of the Senior Leadership Team, partnering closely with Clinical Operations, Medical, Regulatory, Biometrics, CMC, Commercial and other functional leaders to drive the successful execution of Amylyx’s development portfolio.

In a lean and evolving biotech environment, this individual will operate both as an enterprise leader and a hands-on program leader, directly supporting key assets while building a scalable program leadership organization over time.

The Opportunity

This is a unique opportunity to shape and define how program leadership is executed within a growing biotech organization at a critical inflection point.

Build a New Function from the Ground Up - design and implement a modern program leadership model, including the evolution from traditional program management to a strategic Program Lead and Program Manager structure.

Operate as a True Peer to Clinical and Medical Leadership - serve as an equal partner to senior leaders across Clinical Operations, Medical, and Regulatory, helping shape asset strategy and execution.

Drive Impact Across the Full Development Lifecycle - lead programs spanning early-phase IND-enabling work through Phase 3 and potential NDA submission, with direct impact on key value-driving milestones.

Balance Strategy and Execution in a Lean Environment - play a dual role as both a strategic leader and hands-on program leader, directly influencing outcomes while building for future scale.

Shape Organizational Culture and Ways of Working - establish a highly collaborative, accountable, and transparent operating model that strengthens alignment across functions and reduces organizational friction.

Scale with the Portfolio - build and develop a high-performing team over time, aligned to the growth of the pipeline and key clinical milestones.

Responsibilities

Strategic Program Leadership

• Partner with Clinical Operations and Medical leadership to define and execute development strategies and plans across programs
• Drive program-level decision-making, including risk assessment, trade-offs, and prioritization
• Ensure alignment between asset strategy, clinical execution, and regulatory pathways
• Present program updates, risks, and opportunities to Executive Leadership and Board of Directors

Cross-Functional Integration & Alignment

• Serve as the central integrator across Medical, Clinical Operations, Regulatory, Biometrics, CMC, Commercial and other key functions
• Drive clarity of roles, decision-making, and accountability across program teams
• Proactively identify and resolve cross-functional misalignment, gaps, and competing priorities

Hands-On Program Execution

• Directly serve as Program Lead for one or more key assets, particularly in the early phase of the role
• Lead cross-functional team meetings, execution planning, and milestone delivery
• Translate strategic objectives into clear, aligned execution plans

Build & Scale Program Leadership

• Design and implement a program leadership model, including Program Leads and Program Managers
• Hire, develop, and lead program leadership talent over time as the organization grows
• Establish best practices, governance frameworks, and ways of working that enable scalability

Portfolio & Executive Contribution

• Contribute to portfolio prioritization, resource allocation, and strategic planning discussions at the leadership level
• Provide clear, actionable insights and recommendations to executive leadership
• Support the evolution of Amylyx’s development organization as it scales toward key clinical and regulatory milestones

Required Qualifications

• Advanced degree (PhD, MD, PharmD, or MD) in a relevant scientific discipline preferred; equivalent experience in drug development and program leadership will also be considered
• 20+ years of experience in the pharmaceutical or biotechnology industry, including significant experience leading cross-functional drug development programs
• Lead integrated clinical development plans (CDPs)
• Overseen protocol design, endpoints, and trial execution
• Demonstrated success in regulatory interactions (FDA, EMA)
• Significant experience leading cross-functional drug development programs, ideally spanning early development through late-stage clinical and/or regulatory milestones
• Demonstrated success in regulatory interactions (FDA, EMA)
• Prior experience serving as a Program Lead, Development Team Leader (DTL), Asset Team Lead or equivalent role, with accountability for cross-functional program execution
• Demonstrated ability to partner with Clinical Operations, Medical, and Regulatory leaders as a peer, influencing strategy and execution
• Experience operating in a biotech or similarly lean, fast-paced environment, with comfort navigating ambiguity and evolving priorities
• Proven track record of building or scaling teams and/or functions within a matrixed organization
• Strong leadership and collaboration skills, with the ability to align diverse stakeholders and drive decision-making in complex environments
• Hands-on, execution-oriented leadership style, with willingness to engage directly in program delivery when needed
• Excellent communication and interpersonal skills, with the ability to bridge scientific, clinical, and business perspectives

Work Location and Conditions

• At Amylyx, we proudly support remote work opportunities within the United States. However, due to business considerations candidates must be able to attend meetings at our office in Cambridge, MA on a regular basis.  Preference will be given to candidates who reside in the New England region and can be in person on an as needed basis. Currently, we are not considering applicants from Alaska, Arizona, Hawaii, Michigan and Tennessee.
• When working remotely, you must have access to a work setting which enables meeting all requirements of the role (including privacy, reliable internet access, phone, ability to video conference, etc.) at your remote location.

About Graphcore

Graphcore is one of the world’s leading innovators in Artificial Intelligence compute.  

It is developing hardware, software and systems infrastructure that will unlock the next generation of AI breakthroughs and power the widespread adoption of AI solutions across every industry.  

As part of the SoftBank Group, Graphcore is a member of an elite family of companies responsible for some of the world’s most transformative technologies. Together, they share a bold vision: to enable Artificial Super Intelligence and ensure its benefits are accessible to everyone.   

Graphcore’s teams are drawn from diverse backgrounds and bring a broad range of skills and perspectives. A melting pot of AI research specialists, silicon designers, software engineers and systems architects, Graphcore enjoys a culture of continuous learning and constant innovation.  

The Role:

We are developing the next generation of AI compute, a large-scale system-on-chip (SoC) designed to power future high-performance AI systems. As the SoC Validation Lead, you will be responsible for enabling pre-production software to run reliably on new silicon quickly and efficiently, before showing that the silicon meets the highest standards of quality, reliability and functionality, ready for production deployment.

You will lead a team delivering post-silicon validation across the full AI SoC, working across silicon, firmware, and platform levels. The role requires a deep technical understanding, strong hands-on debug experience, and the ability to collaborate effectively with hardware, software, and systems engineering teams.

Responsibilities:

• Define and lead post-silicon validation strategy
  Develop and refine the overall post-silicon validation approach for our AI SoCs, ensuring reliable and timely delivery of validated silicon, architectural correctness, feature robustness, and at-scale system reliability.
• Drive cross-domain debug and issue resolution
  Lead investigation and resolution of complex issues spanning silicon, firmware, operating systems, and platform interactions. Ensure that fixes are effective and sustainable.
• Promote collaboration and shared understanding
  Work closely with design, software, and validation teams to align on quality objectives and debug priorities. Use data-driven insights and clear communication to maintain focus and alignment across teams.
• Advance automation and scalable validation
  Encourage the use of emulation, prototyping, and large-scale validation infrastructure to improve coverage and reduce time to debug.
• Support continuous improvement
  Foster a culture that values learning, transparency, and improvement in validation methods, automation, and analysis.
• Engage with leadership and customers
  Provide clear and concise updates on validation progress, risks, and quality indicators to executive teams and key partners. Contribute to product readiness assessments and roadmap decisions.

About you:

• A systems thinker comfortable working across hardware, software, and integration boundaries.
• A collaborative leader who builds trust and alignment across diverse teams.
• Skilled in technical problem solving and debugging complex post-silicon issues.
• A clear communicator who can simplify complexity and support sound decision-making in fast-paced environments.
• Committed to developing people and promoting an inclusive, high-performing team culture.

Qualifications:

• Bachelor’s degree in Electronic Engineering or equivalent; Master’s preferred.
• 20+ years in silicon, system, or platform validation, including 10+ years in technical leadership.
• Proven experience leading post-silicon validation and bring-up for complex SoCs (AI, GPU, or CPU).
• Strong understanding of SoC architecture, coherency protocols, power management, and interconnects.
• Expertise in debug tools, DFT infrastructure, and validation automation frameworks.
• Proficient in C/C++, Python, and Linux-based environments; experience with large-scale validation clusters is an advantage.
• Excellent communication, collaboration, and stakeholder management skills.

About Graphcore 

At Graphcore, we’re building the future of AI compute.

We’re a team of semiconductor, software and AI experts, with deep experience in creating the complete AI compute stack - from silicon and software to infrastructure at datacenter scale.

As part of the SoftBank Group, backed by significant long-term investment, we are delivering key technology into the fast-growing SoftBank AI ecosystem.

To meet the vast and exciting AI opportunity, Graphcore is expanding its teams around the world.

We are bringing together the brightest minds to solve the toughest problems, in a place where everyone has the opportunity to make an impact on the company, our products and the future of artificial intelligence.

Job Summary 

We are seeking a Director of Silicon Logical Design to lead and scale our Logical Design group within the Silicon department. This role is accountable for the overall strategy, technical direction, execution quality and team development for Graphcores microarchitecture and RTL design efforts. 

The Director will be responsible for ensuring that our logical design methodologies, architectures and RTL implementations meet world class standards for performance, power, area, and schedule. This leader will partner closely with Architecture, Physical Design, Verification, DFT and Program Management teams to ensure successful, predictable silicon delivery aligned with Graphcores long term product roadmap. 

The Team 

The Logical Design team deliver the micro-architecture and RTL that realise our advanced chip architectures. As Director, you will guide this multi site team, strengthen cross functional collaboration, and drive the evolution of our design flows and capabilities. 

Responsibilities and Duties 

Leadership & Strategy 

• Define and execute the strategic roadmap for Logical Design, ensuring alignment with Graphcores silicon and product strategy. 

• Lead, grow and mentor a high performing RTL/micro architecture design organisation. 

• Establish and implement best in class design methodologies, documentation standards and quality metrics. 

• Drive continuous improvement across team structure, workflows, tooling, and design processes. 

Technical Ownership 

• Provide technical oversight of micro architecture specification and RTL development across all major blocks and subsystems. 

• Guide architectural feasibility studies, contribute to architectural trade offs and micro architecture definition. 

• Oversee the integration of third party IP, complex application specific blocks, and high performance custom designs. 

• Ensure robust design sign off through high quality linting, synthesis, CDC/RDC, timing closure and coverage metrics. 

Cross-Functional Collaboration 

• Partner closely with Physical Design, Verification, DFT, Architecture and Program Management teams to ensure cohesive planning and execution. 

• Foster strong communication across teams and global sites, ensuring alignment on priorities, risks and deliverables. 

• Support silicon bring-up and debug efforts by providing expert guidance and deep understanding of RTL behaviour and architecture. 

Execution & Delivery 

• Own delivery of high quality, on schedule RTL for multiple parallel silicon programs. 

• Establish scalable project planning and tracking practices, including resource planning and risk mitigation. 
• Champion design automation and infrastructure improvements to accelerate productivity and improve design quality. 

Essential Skills & Experience 

• Degree in Computer Science, Electrical Engineering or a related field; advanced degree preferred. 

• Extensive experience in digital logical design, micro-architecture and RTL development for large scale, high performance silicon projects. 

• Proven success leading and developing technical teams in a semiconductor environment. 

• Deep expertise in SystemVerilog or VHDL and familiarity with modern digital design flows. 

• Strong ability to diagnose and resolve complex design issues, including via scripting/programming (Python, Tcl, etc.). 

• Demonstrated excellence in cross functional leadership and communication across global teams. 

• Strong organisational skills with ability to manage multiple priorities and drive execution in fast-paced environments. 

Desirable Experience 

• Processor or accelerator micro architecture. 

• High-speed serial interfaces and complex, high bandwidth IP blocks. 

• Arithmetic pipeline design and floating point datapaths. 

• Advanced synthesis, timing analysis, power analysis, and logical equivalence checking. 

• Design-for-test methodologies. 

• Power integrity and silicon device level understanding. 

• Experience with silicon bring-up and post-silicon validation. 

• Program planning and multi-project execution leadership. 

About the Role

As the Director, Strategy & Operations - Growth, you will report to the VP, Growth and serve as the leader of Iterative Health's biological specimen collections business. This is a senior, highly autonomous role for an operator who is equally comfortable setting strategy and rolling up their sleeves to execute. You will own the go-to-market strategy, lead the full build-out of the business, and hold accountability for performance. You will also lead and develop the team that runs the day-to-day of collections operations. The ideal candidate brings a strong strategic and analytical foundation from management consulting or a high-growth startup environment, paired with the operational horsepower and ownership mindset to build something from the ground up.

Responsibilities

Go-to-Market Strategy

• Own the go-to-market strategy for Iterative Health's biological specimen collections business — defining the service offering, target customer segments, competitive positioning, and path to scale
• Define what we sell and how we sell it: Work with Business Development to scope the collections service model, establish pricing frameworks, and develop the materials and narrative needed to bring the offering to market
•  Identify and size the resourcing, infrastructure, and capability requirements needed to support the strategy and inform investment decisions

Business Build-Out

•  Lead the end-to-end build-out of the biological specimen collections business — standing up operational capabilities, and establishing the processes and infrastructure needed to execute at scale
• Own vendor contracting and relationships, including selection, negotiation, onboarding, and ongoing performance management for all collections-related vendors
• Partner with the Business Development team to develop and progress a pipeline of collections studies, supporting sponsor engagement and proposal development
• Work cross-functionally with site operations leaders to identify and onboard the right site network to support collections studies

Business Performance Ownership

• Own execution quality and sponsor satisfaction on active collections studies, serving as the senior point of escalation and ensuring trials are delivered to the highest standard
• Define and track KPIs across the business; use performance data to identify gaps, course-correct quickly, and communicate progress to senior leadership

Team Leadership

• Lead, develop, and hold accountable a team that includes pre-screeners, central Clinical Research Coordinators, and a Clinical Operations Manager — setting clear performance targets and maintaining a high-performance culture
• Train team members on workflows, protocols, and quality standards, and ensure the team has the tools, processes, and support needed to execute at pace
• Set the operational tempo for the team — running structured operations, maintaining visibility into study and team performance, and driving accountability at every level

Required Qualifications

• BS/BA or higher degree; advanced degree (MBA, MPH, or equivalent) strongly preferred
• 7+ years of experience in a strategic and operational role, with meaningful exposure to building or scaling a business — prior experience in management consulting, a high-growth startup, or a general management capacity is strongly preferred
• Experience leading cross-functional build-outs — standing up new capabilities, managing vendors, and driving commercial pipelines
• Proven people leadership experience with the ability to recruit, develop, and hold accountable a high-performing team
• Exceptional organizational and project management skills with the ability to manage multiple high-stakes workstreams simultaneously
• Strong executive presence and communication skills — able to represent the business credibly with sponsors, vendors, and senior internal stakeholders
• Comfortable operating with significant autonomy and building structure in ambiguous, fast-moving environments

Preferred Qualifications

• Experience in life sciences, clinical research, or healthcare services — particularly in biological specimen collections studies

About the Role

As the Manager, Growth, you will play a critical operational role at the center of Iterative Health's two core growth engines in Cardiology: expanding our sponsor portfolio and scaling our site network. This is a high-visibility, high-impact role for a sharp operator who thrives on process ownership, cross-functional coordination, and getting things done in a fast-moving environment. You will own the internal mechanics of business development — keeping the pipeline moving, deals progressing, and sponsors well-served — while simultaneously driving the operational build-out of new clinical research sites from contract execution through first study activation. The ideal candidate brings a strategic and operational mindset, is energized by variety, and is able to manage multiple workstreams with rigor and speed.

Responsibilities

Sponsor Growth: Business Development & Alliance Management Support

• Own the end-to-end internal business development process from initial sponsor engagement through contract execution, serving as the single internal touchpoint for new contracts
• Keep the business development pipeline organized and visible by maintaining up-to-date reporting on opportunity status, next steps, and deal progression
• Support the Director of Research Partnerships in preparing for key sponsor interactions — developing pitches and proposals, building conference materials, and ensuring the team shows up well-prepared for high-stakes meetings
• Support sponsor account meetings through internal data gathering, performance reporting, and post-meeting follow-through
• Continuously identify opportunities to streamline and improve the business development process to accelerate deal pull-through and reduce time to contract close

Site Network Growth: De Novo Site Builds 

• Partner with the Director of Clinical Research to support the end-to-end process of standing up de novo clinical research sites 
• Serve as the operational connective tissue during site stand-up, tracking progress, surfacing blockers, and ensuring all cross-functional inputs come together on schedule
• Work with the Director of Clinical Research to continuously evaluate and improve the site stand-up process — identifying inefficiencies, building out playbooks, and creating repeatable frameworks that scale as the network grows

Required Qualifications

•  BS/BA or higher degree
• 4+ years of experience in a strategic and operational role, such as management consulting, business operations, or growth/strategy at a high-growth startup
• Demonstrated ability to own and manage complex, cross-functional processes end-to-end with strong attention to detail
•  Excellent organizational skills with experience managing multiple projects and workstreams simultaneously in a fast-paced environment
• Strong communicator with the ability to synthesize information, build materials, and engage effectively with internal and external stakeholders
• Comfortable working with ambiguity and building structure where it doesn't yet exist

Preferred Qualifications

• Experience in life sciences, clinical research, or healthcare 
• Familiarity with clinical trial operations, site networks, or sponsor/CRO relationships

POS-32553

Job Description

At HubSpot, we aim to give employees the same thoughtful, high-quality experience we offer our customers, every day of their journey with us — from their first day in the office to their last. As part of the Global Facilities team, the Senior Manager, Facilities – Americas leads operations across our Americas offices, ensuring safe, reliable, and inspiring workplaces where employees and visitors can do their best work.

This role owns day-to-day facilities operations and workplace experience for our directly leased and partner-managed spaces in the Americas, manages regional vendors and building relationships, and leads a distributed team of coordinators and contingent staff. You will partner closely with Real Estate, Security, Business Technology, Workplace Experience and other key stakeholders to deliver a data-informed, employee-centric facilities strategy that scales with HubSpot’s growth.

In this role you will

Regional leadership & team management

• Lead and develop a high-performing regional facilities team (full-time, temporary, and contractor staff) across multiple Americas locations (e.g., Cambridge, San Francisco, Bogotá), providing coaching, direction, and day-to-day support.
• Set clear goals and priorities aligned to global Facilities and drive consistent operational standards across sites.
• Delegate and oversee work through our internal ticketing system, ensuring timely, high-quality responses to employee and stakeholder requests.

Facilities operations & maintenance

• Own day-to-day facilities operations for the Americas offices, including office readiness, space standards, and preventative maintenance for core building systems (HVAC, plumbing, electrical, furniture, fixtures, and equipment).
• Coordinate and resolve building and infrastructure issues (e.g., furniture failures, water heater problems, IDF/MDF spaces) in partnership with vendors, building engineers, and internal teams, from initial triage through to resolution and communication.
• Ensure that meeting rooms, cafes, collaboration spaces, and wellness areas meet high standards of quality, functionality, and cleanliness, supporting employee productivity and comfort.
• Maintain and update team workflows for all americas offices 

Vendor, building & contract management

• Serve as the primary Facilities point of contact for property managers, landlords, and key building stakeholders across the Americas region, maintaining strong relationships and clear operating rhythms.
• Source, scope, and manage vendors for services such as janitorial, carpet and floor care, furniture, blinds, mechanical/plumbing, and specialty trades — including obtaining quotes, validating scope, scheduling work, and monitoring performance.
• Partner with Procurement and Finance on purchase requests, POs, and cost optimization (e.g., scheduling to avoid overtime labor where possible, aligning work with building access windows).

Workplace experience & front-of-house support

• Ensure a consistently excellent front-of-house and visitor experience in Americas offices, including reception standards, wayfinding, and event support in collaboration with on-site teams.
• Oversee coordination of mail, shipping/receiving, and logistics, including high-value and international shipments in partnership with Business Technology and external carriers.
• Support office events, intentional gatherings, and other on-site activities by ensuring facilities, services, and vendors are aligned to program needs.
• Manage large office moves, terminations including desk assignments. 
• Maintain and update floorplans when changes happen or new offices open, this includes updating the CAFM system to ensure floorplans are up to date.
• Review and coordinate parking assignments notifying the appropriate individuals to provide access.

Health, safety, security & emergency readiness

• Act as a key regional contact for facilities-related emergencies, coordinating with Security, IT, and local building teams to respond to incidents across Americas sites (e.g., IDF/MDF issues, building systems failures, safety concerns).
• Maintain and contribute to emergency contact lists, playbooks, and on-site procedures for multiple locations, ensuring information is current, accurate, and visible to the right stakeholders.
• Partnering with Security and local offices leads to support physical security practices (e.g., access control, cameras, vendor access) and align with HubSpot’s safety expectations.

Projects, space changes & cross-functional collaboration

• Lead and support facilities components of office projects in the Americas (e.g., reconfigurations, furniture changes, programmatic improvements, capital projects) in partnership with Real Estate, Construction partners, BT, and local stakeholders.
• Collaborate closely with global Facilities and Real Estate peers to ensure alignment on standards, data, and reporting, and to share best practices across regions.
• Use ticketing and space data to identify trends, propose improvements, and inform prioritization and investment decisions across the Americas portfolio.

Documentation, communication & knowledge sharing

• Maintain and enhance Facilities documentation for Americas offices, including wiki content, emergency information, operating procedures, and office-specific guides.
• Communicate proactively with employees, partners, and leadership about facilities work, impacts, and timelines, ensuring transparency and building trust.

Our ideal candidate

• Has 7+ years of experience in facilities management, workplace operations, property management, or a related field, including multi-site responsibility and complex office environments.
• Has at least 5+ Years of people management experience, leading and developing distributed teams and working with contingent staff and vendors.
• Demonstrates strong vendor and stakeholder management skills and is comfortable working directly with landlords, property managers, and specialty contractors to solve operational issues.
• Is highly organized, able to prioritize across multiple offices, manage competing deadlines, and stay calm and effective in time-sensitive or emergency situations.
• Communicates clearly and empathetically in writing and in person, tailoring their style for employees, senior leaders, vendors, and building teams.
• Is data-informed and comfortable using ticketing systems and basic reporting to spot patterns, drive improvements, and measure the impact of facilities programs.
• Brings a strong customer-first mentality, with a passion for creating inclusive, welcoming, and accessible spaces for all employees and visitors.
• Aligns with HubSpot’s HEART values and is eager to collaborate across regions and functions to help our global team thrive.

Knowledge of Health & Safety practices, building systems, environmental sustainability, and physical security is a strong plus. Additional languages are a plus.

Diversity & inclusion

Confidence can sometimes hold people back from applying for a role, but there’s no such thing as a “perfect” candidate. HubSpot is a place where everyone can grow, so however you identify and whatever background you bring, please apply if this role excites you and you’re eager to support our teams across the Americas every day.

About HubSpot

HubSpot (NYSE: HUBS) is a leading customer relationship management (CRM) platform that provides software and support to help businesses grow better. We build marketing, sales, service, and website management products that start free and scale to meet our customers’ needs at any stage of growth. We’re also building a company culture that empowers people to do their best work and supports a diverse, inclusive workplace.

Thanks to the work of every employee globally, HubSpot has been recognized for our culture and as a great place to work by Glassdoor, Great Place to Work, Comparably, Fortune, Entrepreneur, and more. Today, thousands of employees work across the globe in HubSpot offices and remotely.

By submitting an application, candidates agree that HubSpot may collect their personal data for recruiting, global organization planning, and related purposes, as outlined in HubSpot’s Privacy Notice.

Our Mission: Helping Millions of Organizations Grow Better

Team Overview

Our Enterprise Sales team drives growth by connecting large organizations (500–5,000 employees) with HubSpot’s solutions. We balance transactional and complex deals, collaborating with internal teams to achieve shared goals.

In this role, you’ll get to: 

• Position the value of HubSpot’s software, focusing on companies primarily between 500-5000 employees
• Educate and guide prospects through the buyer’s journey to help them learn how HubSpot can grow their business
• Manage a pipeline of self-sourced leads to identify, engage, and develop relationships with potential buyers
• Dissect and qualify prospects’ business goals to determine if HubSpot can be a strategic investment for their business’ growth
• Close business with new and existing customers at or above quota level
• Partner with marketing and technology departments to execute sales strategy as the company introduces enhancements to existing solutions and/or releases new products
• Bring your thinking, strategies, and ideas to advance our company’s values, unique culture, and vision for the future

We are looking for people who have:

• A minimum of 5 years managing full sales cycles (prospecting to close)
• A minimum of 3 years of SaaS sales experience
• Proven and consistent track record as a top producer in sales roles
• Experience delivering product demos to diverse audiences
• Experience in value-based selling (e.g., Challenger Sale)
• Commitment to achieving ambitious sales targets
• A positive outlook and hold themselves accountable to results
• A strong growth mindset and desire for continuous learning
• Resilience and adaptability

#LI-PZ1

Please note: This role is hired on an ongoing basis, and we are currently targeting start dates in Q2 2026 and beyond. If you choose to apply, your information will be reviewed by our team and we will reach out to you if your background aligns with available or future openings. 

As a Growth Specialist (Account Executive) on the Mid-Market sales team, you will identify, source and close good-fit prospects. Using strong consultative selling skills, you will balance contacting warm inbound leads and driving self-sourced leads for your pipeline, while also partnering closely with internal stakeholders to achieve team goals and work towards HubSpot’s mission.

In this role, you’ll get to:

• Position the value of HubSpot’s software and the Inbound methodology to medium-sized businesses 
• Educate and guide prospects through the buyer’s journey to help them learn how HubSpot can grow their business
• Identify and Prospect into good fit accounts that may or may not have HubSpot knowledge or experience
• Manage a pipeline of inbound and self-sourced leads to identify, engage, and develop relationships with potential buyers
• Dissect and qualify prospects’ business goals to determine if HubSpot can be a strategic investment for their business’ growth
• Close business with new and existing customers at or above quota level
• Partner with marketing and technology departments to execute sales strategy as the company introduces enhancements to existing solutions and/or releases new products
• Bring your thinking, strategies, and ideas to advance our company’s values, unique culture, and vision for the future
• Work with and develop business development representatives who partner with you to also develop pipeline opportunities

We are looking for people who:

• Have extensive relevant full-cycle sales experience
• Have the desire and commitment to do what it takes to be successful in sales
• Can effectively communicate with internal teams while being remote and working autonomously
• Have a positive outlook, growth mindset and a strong ability to take responsibility for their successes and failures
• Have exceptional consultative selling and closing skills
• Demonstrate top tier organizational skills and a repeatable sales process
• Are Top Producers in their current role
• Have a sharp focus on their goals and a belief that their daily, weekly and monthly activities will help achieve them

Minimum qualifications for the Mid-Market Account Executive:

• 3+ years of relevant full-cycle sales experience
• Prospecting and closing net new business
  • Strong Hunter Mentality
• Cross-selling/up-selling to current customers
• Multi approach out-bounding methods to draw in new business

HubSpot welcomes individuals to join our Sales team as a Business Development Representative (BDR). As part of our commitment to building a hybrid company, BDRs can be flexible with their work location with the choice to either be based in Cambridge, Massachusetts, or remotely in the US. 

🚀 Join HubSpot as an Outbound Business Development Representative (BDR)
📍 Cambridge, MA or Remote (US)

We’ll be honest — sales isn’t easy, and it’s not for everyone. But for those who love a challenge, thrive on results, and want to launch a long-term path in sales, it’s incredibly rewarding.

If you’re looking to “try out” sales or just dip a toe in, this probably isn’t the role for you. But, if you’re the kind of person who wakes up hungry to compete, thrives on setting and smashing goals, and wants to build a career in tech sales from the ground up — we want to talk to you.

At HubSpot, our BDRs are not only the first point of contact for our prospects—they’re also developing the skills and mindset to become our next generation of Account Executives. This is not a placeholder job — it’s the first chapter of a high-growth sales career designed for those who want to build skills, embrace feedback, move fast, and grow even faster.

The Role:
As an Outbound BDR, you’ll play a key role in HubSpot’s growth engine. You'll be the first touchpoint for many of our future customers, sparking conversations through strategic outreach, uncovering pain points, and qualifying leads. You’ll partner closely with Account Executives to deliver high-quality meetings that drive pipeline, impact, and revenue. Along the way, you’ll sharpen your sales toolkit daily and gain exposure to a world-class sales organization.

What You’ll Do:

• Own and execute outbound prospecting through high-volume outreach (60–100+ activities/day) via phone, email, and LinkedIn.
• Collaborate with Account Executives to target strategic accounts and refine outreach strategy.
• Qualify leads based on fit, need, and urgency — and book quality discovery meetings.
• Hit (and exceed) KPIs for activity, meetings delivered, and pipeline impact.
• Grow fast. Learn fast. Get coached. Apply it. Repeat.
  
  

What You Won’t Do:

• Coast. We move fast, we test, we iterate, and we compete.
• Wait for someone to tell you what to do. We value self-starters who take ownership.
• Treat this as “just a job.” This is a foundational role, setting you up for a successful long term career in sales.
  
  

We’re Looking For People Who:
✅ Are eager to grow long-term within a sales path–if your focus is split between sales and other paths like customer success, marketing, operations, etc, this role likely won’t be the best fit.
✅ Are resilient, coachable, and crave feedback to improve.
✅ Are curious and ask why, not just how.
✅ Set high standards for themselves — and hit them.
✅ Are technologically fluent, adapting to new technologies and leveraging AI in your day-to-day.
✅ Communicate clearly, write thoughtfully, and can confidently conduct a cold call.
✅ Are energized by a fast-paced environment and a bit of friendly competition.
✅ Either have past sales success or have demonstrated excellence in goal-driven roles (think: fundraising, athletics, service industry, etc).

Tools We Use (and You’ll Learn):

• HubSpot (of course)!
• LinkedIn Sales Navigator
• AI Powered Tools across all aspects of the role for research & outreach
• Slack, Zoom, LeadIQ, Google Suite, Zoominfo, and more
  
  

To Apply:
📝 No cover letter required.
📄 Submit your resume.
👉 If you're new to sales, show us your grit: include examples of how you've hit ambitious goals in other roles.
📊 If you’ve been in sales before, highlight metrics like quota attainment.

Important information about the position.

Bottom Line:
We’re looking for future stars, not just seat-fillers. If you want to grow into an elite sales professional and are ready to work hard, get uncomfortable, and see what you're really capable of — this is your shot.

HubSpot welcomes individuals to join our Sales team as a Business Development Representative (BDR). As part of our commitment to building a hybrid company, BDRs can be flexible with their work location with the choice to either be based in Cambridge, Massachusetts, or remotely in the US. 

🚀 Join HubSpot as an Outbound Business Development Representative (BDR)
📍 Remote (US) or Cambridge, MA

We’ll be honest — sales isn’t easy, and it’s not for everyone. But for those who love a challenge, thrive on results, and want to launch a long-term path in sales, it’s incredibly rewarding.

If you’re looking to “try out” sales or just dip a toe in, this probably isn’t the role for you. But, if you’re the kind of person who wakes up hungry to compete, thrives on setting and smashing goals, and wants to build a career in tech sales from the ground up — we want to talk to you.

At HubSpot, our BDRs are not only the first point of contact for our prospects—they’re also developing the skills and mindset to become our next generation of Account Executives. This is not a placeholder job — it’s the first chapter of a high-growth sales career designed for those who want to build skills, embrace feedback, move fast, and grow even faster.

The Role:
As an Outbound BDR, you’ll play a key role in HubSpot’s growth engine. You'll be the first touchpoint for many of our future customers, sparking conversations through strategic outreach, uncovering pain points, and qualifying leads. You’ll partner closely with Account Executives to deliver high-quality meetings that drive pipeline, impact, and revenue. Along the way, you’ll sharpen your sales toolkit daily and gain exposure to a world-class sales organization.

What You’ll Do:

• Own and execute outbound prospecting through high-volume outreach (60–100+ activities/day) via phone, email, and LinkedIn.
• Collaborate with Account Executives to target strategic accounts and refine outreach strategy.
• Qualify leads based on fit, need, and urgency — and book quality discovery meetings.
• Hit (and exceed) KPIs for activity, meetings delivered, and pipeline impact.
• Grow fast. Learn fast. Get coached. Apply it. Repeat.
  
  

What You Won’t Do:

• Coast. We move fast, we test, we iterate, and we compete.
• Wait for someone to tell you what to do. We value self-starters who take ownership.
• Treat this as “just a job.” This is a foundational role, setting you up for a successful long term career in sales.
  
  

We’re Looking For People Who:
✅ Are eager to grow long-term within a sales path–if your focus is split between sales and other paths like customer success, marketing, operations, etc, this role likely won’t be the best fit.
✅ Are resilient, coachable, and crave feedback to improve.
✅ Are curious and ask why, not just how.
✅ Set high standards for themselves — and hit them.
✅ Are technologically fluent, adapting to new technologies and leveraging AI in your day-to-day.
✅ Communicate clearly, write thoughtfully, and can confidently conduct a cold call.
✅ Are energized by a fast-paced environment and a bit of friendly competition.
✅ Either have past sales success or have demonstrated excellence in goal-driven roles (think: fundraising, athletics, service industry, etc).

Tools We Use (and You’ll Learn):

• HubSpot (of course)!
• LinkedIn Sales Navigator
• AI Powered Tools across all aspects of the role for research & outreach
• Slack, Zoom, LeadIQ, Google Suite, Zoominfo, and more
  
  

To Apply:
📝 No cover letter required.
📄 Submit your resume.
👉 If you're new to sales, show us your grit: include examples of how you've hit ambitious goals in other roles.
📊 If you’ve been in sales before, highlight metrics like quota attainment.

Important information about the position.

Bottom Line:
We’re looking for future stars, not just seat-fillers. If you want to grow into an elite sales professional and are ready to work hard, get uncomfortable, and see what you're really capable of — this is your shot.

POS-9034

About the Team

Commerce Hub is building the backbone for businesses to sell, bill, get paid, and manage revenue inside HubSpot. Our systems handle billions of dollars in transactions for our customers, so correctness, clarity, and predictability matter. We’re creating an AI-first commerce platform that’s deeply integrated with HubSpot’s CRM - simple, consistent, and extensible across every part of the seller and buyer experience.

About the Role

We’re looking for a Principal Software Engineer to help shape the technical future of Commerce Hub. This is a very hands-on role. You’ll write code, dive into services, review tough designs, debug messy systems, and directly own the architecture behind some of the most critical surfaces in CPQ, Billing, Payments, and Revenue OS.

What You’ll Do

Build a simple, consistent, extensible platform

• Shape the technical roadmap across CPQ, Billing, and Payments with strong, opinionated patterns.
• Define and evolve core domain models so pricing, products, contracts, invoices, and payments behave predictably everywhere.
• Create frameworks that make the platform easy to extend without adding complexity.

Be a deeply hands-on, high-leverage builder

• Write code regularly. Lead design reviews and build high-impact systems end-to-end.
• Own large multi-team initiatives that span CPQ, Billing and Payments.
• Take prototypes to production at scale.

Lead architectural direction

• Set patterns for extensibility, contract boundaries, financial correctness, event-driven consistency, and how AI/agents safely interact with commerce objects.
• Push for simplicity where the domain wants to get complicated, and consistency where surfaces can drift.

Partner deeply with product leadership

• Influence product strategy across CPQ, Buyer Portal, and Revenue OS.
• Help teams make clear tradeoffs between speed, correctness, compliance, and long-term platform health.

Raise the bar across the org

• Mentor senior engineers and tech leads.
• Drive thoughtful design decisions and guide learnings from incidents and large migrations.
• Help teams align on patterns that reduce complexity and increase reliability.

What You Bring

• Proven experience building and scaling distributed systems with strict correctness requirements.
• Background working with complex state machines, financial flows, or high-integrity data models.
• Strong architectural instincts with a bias toward simplicity, consistency, and well-defined boundaries.
• The ability to work horizontally across many teams and get alignment on platform patterns.
• A habit of turning ambiguity into clear plans and working software—and staying hands-on every step of the way.

POS-9034

About the Team

Commerce Hub is building the backbone for businesses to sell, bill, get paid, and manage revenue inside HubSpot. Our systems handle billions of dollars in transactions for our customers, so correctness, clarity, and predictability matter. We’re creating an AI-first commerce platform that’s deeply integrated with HubSpot’s CRM - simple, consistent, and extensible across every part of the seller and buyer experience.

About the Role

We’re looking for a Principal Software Engineer to help shape the technical future of Commerce Hub. This is a very hands-on role. You’ll write code, dive into services, review tough designs, debug messy systems, and directly own the architecture behind some of the most critical surfaces in CPQ, Billing, Payments, and Revenue OS.

What You’ll Do

Build a simple, consistent, extensible platform

• Shape the technical roadmap across CPQ, Billing, and Payments with strong, opinionated patterns.
• Define and evolve core domain models so pricing, products, contracts, invoices, and payments behave predictably everywhere.
• Create frameworks that make the platform easy to extend without adding complexity.

Be a deeply hands-on, high-leverage builder

• Write code regularly. Lead design reviews and build high-impact systems end-to-end.
• Own large multi-team initiatives that span CPQ, Billing and Payments.
• Take prototypes to production at scale.

Lead architectural direction

• Set patterns for extensibility, contract boundaries, financial correctness, event-driven consistency, and how AI/agents safely interact with commerce objects.
• Push for simplicity where the domain wants to get complicated, and consistency where surfaces can drift.

Partner deeply with product leadership

• Influence product strategy across CPQ, Buyer Portal, and Revenue OS.
• Help teams make clear tradeoffs between speed, correctness, compliance, and long-term platform health.

Raise the bar across the org

• Mentor senior engineers and tech leads.
• Drive thoughtful design decisions and guide learnings from incidents and large migrations.
• Help teams align on patterns that reduce complexity and increase reliability.

What You Bring

• Proven experience building and scaling distributed systems with strict correctness requirements.
• Background working with complex state machines, financial flows, or high-integrity data models.
• Strong architectural instincts with a bias toward simplicity, consistency, and well-defined boundaries.
• The ability to work horizontally across many teams and get alignment on platform patterns.
• A habit of turning ambiguity into clear plans and working software—and staying hands-on every step of the way.

POS-32567

Application deadline: 5pm ET Friday 5/8

About the role

The Salesforce Competitive Expert is a senior, customer-facing specialist who owns HubSpot’s competitive strategy against Salesforce in our most complex, upmarket CRM evaluations and rip-and-replace motions. You’ll operate as a highly autonomous, intrapreneurial leader within PreSales, managing your own book of strategic deals while building the playbooks, assets, and enablement that help HubSpot systematically win more Salesforce competes and drive NNARR.

What you’ll do

• Act as the lead Salesforce competitive expert on qualified strategic deals—joining discovery, technical validation, and executive meetings to de-risk decisions and secure tech wins against Salesforce.
• Own and continuously evolve the Salesforce Competitive Playbook, codifying winning narratives, talk tracks, demo strategies, and “assertive selling” motions for Salesforce rip-and-replace and net-new CRM evaluations.
• Partner with Account Executives, core SEs, and implementation partners to design solution blueprints, migration paths, and TCO/ROI cases that build unshakable confidence in choosing HubSpot over Salesforce.
• Deliver scalable enablement for Sales, PreSales, and partners (training, battlecards, assets) that elevates our collective ability to compete and increases win rates on Salesforce deals.
• Serve as the central feedback loop from the field to Competitive Intelligence, Product, and Marketing, surfacing patterns from wins/losses and informing roadmap and GTM strategy.
• Proactively analyze pipelines to prioritize high-impact opportunities, manage your own bandwidth, and protect capacity in line with Expert Program guardrails.

What you’ll bring

• Deep Salesforce expertise (must-have): Extensive, hands-on Salesforce experience (e.g., Admin / Sales Cloud configuration, implementation, or architecture) with certified-level depth and the ability to “speak admin to admin.”
• HubSpot & operator credibility: Strong HubSpot CRM fluency plus real-world operator experience using HubSpot to drive business outcomes, enabling you to translate between both ecosystems with empathy and authority.
• Autonomy & business ownership: Proven track record of working independently, managing your own portfolio of complex deals, and building new processes/playbooks from scratch in ambiguous, high-stakes environments.
• Competitive, strategic mindset: You think several moves ahead, love deconstructing competitor strategies, and can reframe “Salesforce as the safe choice” into a compelling case for HubSpot through narrative, TCO, and technical validation.
• Executive presence & communication: Comfort engaging technical stakeholders and C‑level executives, simplifying complex concepts, and driving clear, confident decisions in the room.
• Innovative, system-builder orientation: You’re passionate about helping HubSpot win upmarket and naturally turn one-off deal work into reusable assets, frameworks, and enablement that scale across regions and specialties.

The Role:

Reporting to the Senior Director of Pharmacovigilance (PV) Operations, the Associate Director, PV Operations will provide vendor oversight and review of ICSR processing for assigned investigational products. They will ensure compliance and adherence to Safety processes and SOPs as well as manage and analyze data from the Global Safety Database. This SME will be responsible for PV operations’ role in Phase 1, 2, & 3 clinical studies, inclusive of inspection readiness, reconciliation, SMP maintenance, and site and regulatory authority reporting oversight. They will work in close collaboration with PV physicians and PV scientists on operational safety and case quality issues.

Responsibilities:

• Manage and support the relationship with safety vendor(s) to ensure effectiveness, quality and compliance of all outsourced activities.
• Provide Sponsor oversight of operational safety responsibilities, including the timely and accurate execution of the processes defined within the applicable Safety Management plans.
• Participate in daily management, operational oversight and execution of operational safety tasks for assigned Nuvalent clinical programs.
• Review incoming adverse event reports and communications from vendors to determine action required and ensure prompt review, follow-up, and timely submission of expedited safety reports.
• Oversee case workflow (case receipt through submission) between safety vendor and Nuvalent Pharmacovigilance team.
• Ensure safety case queries are resolved as per defined processes (interfacing with safety physicians, clinical operations team, other cross-functional teams within Nuvalent, and clinical vendors, as required) and facilitate case closure within required timelines.
• Serve as PV operations SME on safety reporting processes according to study protocol.
• Participate in the development and maintenance of SOPs, forms, plans, systems, and guidance documents to ensure compliance with all applicable regulatory requirements or guidelines, GVP and industry best practices.
• Serve as resource and contact for other functions within the company for pharmacovigilance
• operational activities.
• Serve as Pharmacovigilance representative for the operational aspects of the SAE reconciliation
•  
• Responsible for the development of safety management plans for assigned programs, and associated documents to ensure that study-specific and Regulatory Authority reporting requirements are met and that workflow responsibilities between CROs, and Nuvalent are clearly delineated and adhered to

Competencies Include:

• Excellent written and verbal communication skills.
• Demonstrated communications expertise with the ability to articulate, influence, and work successfully with internal/external stakeholders and within a matrixed environment.
• Ability to plan and handle multiple responsibilities simultaneously and still meet high quality and timeliness standards under pressure.
• Demonstrated contribution to strategy and innovation. Contributes to or leads actionable strategies.
• Demonstrated project management and prioritization capabilities.

Qualifications:

• Bachelor’s degree in Nursing, RN, Pharmacy, Pharm D., or other relevant health-care related fields.
• 8-10 years of progressive drug safety experience in a biotech/pharma company.
• Clinical Development experience.
• Strong knowledge of current and emerging regulatory requirements including EMA GVP Modules, FDA IND and NDA reporting requirements, ICH, CIOMS
• Ability to interpret and follow regulatory guidelines.
• Proven knowledge of Good Documentation Practices and cGXPs.
• Basic knowledge of MedDRA coding.
• Experience in ICSR case-processing and reporting.
• Experience working in and with safety databases.
• Direct experience managing relationships with service providers or external business partners

Additional Information:

Nuvalent is committed to fair and equitable compensation practices, aiming to provide employees with competitive total rewards packages.

The targeted salary range reflects what Nuvalent reasonably and in good faith expects to offer for this position at the time of posting, but the final salary determination may be within or outside this range based on various factors, including, but not limited to, experience, skills, education, and market factors.  The range will be reviewed regularly and is subject to change.

Nuvalent also offers a comprehensive benefit package to support our employees at each stage of their career, financial, health, and well-being journey, including medical, dental, and vision insurance, 401(k) retirement savings plan, generous paid time off (including a summer and winter company shutdown), and much more.

The Senior Employer Branding Manager is responsible for developing and executing strategies that highlight our culture, values, and employee experience to attract top talent and engage current employees. This role combines storytelling, content creation, video and photography production, and data-driven program design to position CMT as an employer of choice. You’ll own the employee-facing content that shapes how it feels to work here — from the company newsletter to the videos and photos that show the real humans behind the mission — and you’ll support the in-person events that bring our culture to life. This role reports to the Head of Branding and Internal Communications.

Responsibilities:

• Develop and lead the execution of a comprehensive employer branding strategy aligned with CMT’s culture and talent goals
• Own the company newsletter end-to-end — editorial calendar, writing, editing, and measurement — making it something employees actually open and read
• Craft compelling content across written, social, video, and photo formats (social posts, career site updates, blogs, internal comms, employee spotlights, team stories, recruiting videos, event recaps) that highlights our mission, values, and employee experience, ensuring consistency across all touchpoints
• Build and run crowdsourced content programs that get people across the company creating — employee creator programs, content challenges, employee advocacy — equipping teammates with templates, prompts, and light coaching so the stories come from the people living them
• Partner with People Operations, Marketing, and Leadership to design campaigns that engage potential candidates and inspire current employees
• Analyze eNPS, engagement survey data, and other employee sentiment metrics to identify what’s working and where to invest — then design programs that move the numbers
• Monitor and manage CMT’s employer reputation across online sources where candidates and employees rate us — Glassdoor, LinkedIn, Google, Indeed, Comparably, Built In, and emerging platforms — tracking sentiment, responding to reviews, surfacing themes for leadership, and building proactive engagement strategies
• Manage external partners when needed — videographers, photographers, freelance writers, designers, and agencies — keeping work on brand, on schedule, and on budget
• Provide general support for in-person employee and recruiting events — offsites, all-hands, career fairs, campus recruiting, ERG events — from planning through on-site execution
• Analyze campaign performance and employer brand metrics to refine strategies and ensure alignment with organizational objectives
• Lead projects to amplify our presence in the job market, including developing employee advocacy programs, applying for workplace awards, and partnering with industry organizations
• Work across teams to identify opportunities for alignment between employer branding efforts and broader brand and content goals
• Stay updated on employer branding trends, tools, and technologies to keep strategies fresh and competitive
• Complete any additional tasks as they arise

Qualifications:

• Bachelor’s degree or equivalent years of experience and/or certification in Marketing, Communications, or a related field
• 5+ years of experience in employer branding, internal communications, talent marketing, content creation, or a related discipline
• Proven ability to develop and execute strategic branding initiatives that deliver measurable results
• Exceptional storytelling skills, with experience crafting engaging content across written, social, video, and photo formats
• Fluency with video editing — you can take raw footage and turn it into something worth watching, using tools like Adobe Premiere, Final Cut, CapCut, or similar
• Comfortable behind a camera — shooting and editing photography for newsletters, social, the career site, and on-site event coverage
• Experience building programs that get other people creating — employee advocacy, creator programs, crowdsourced content — and the coaching instincts to make non-marketers comfortable contributing
• Analytical mindset — comfortable working with eNPS, engagement survey data, and campaign performance metrics, and translating what you find into programs that actually move the numbers
• Experience managing external creative partners (videographers, photographers, freelancers, agencies) on brand, on schedule, and on budget
• Strong project management skills, with the ability to manage multiple priorities and stakeholders effectively
• Comfortable providing hands-on support for in-person events — logistics, setup, run-of-show, on-site execution
• Excellent interpersonal skills, with a demonstrated ability to work collaboratively across teams and departments
• Proficiency in social media platforms, content management systems, and employer branding tools (LinkedIn Talent Brand / Careers Pages / Life Tab, Canva, or similar)
• A solution-oriented mindset with a proactive approach to problem-solving
• Writing and content samples / portfolio required with application — please include examples of written content, video, and any employee-facing programs you’ve built

Nice to Haves:

• Experience with motion graphics, animation, or more advanced video production
• Experience with workplace awards submissions (Built In, Glassdoor, Great Place to Work, etc.)
• Familiarity with HR systems and engagement platforms (Greenhouse, Culture Amp, Lattice, or similar)

Compensation and Benefits:

• Fair and competitive salary based on skills and experience, and annual performance bonus
• Equity may be awarded in the form of Restricted Stock Units (RSUs)
• Medical, Dental, Vision and Life Insurance, matching 401k, short-term & long-term disability and parental leave
• Unlimited Paid Time Off including vacation, sick days & public holidays
• Flexible scheduling and work from home policy depending on role and responsibilities

Additional Perks:

• Work on a mission with real impact: crashes prevented, injuries avoided, lives protected around the world
• Join an industry leader — 65 million drivers protected, powering 140+ programs across 25 countries
• Be part of the team inventing the future of mobility and road safety
• Move fast, own outcomes, do work that matters
• High ownership, small teams, and direct access to leadership — no layers between your work and its impact
• Unlimited PTO, flexible scheduling, competitive salary, annual performance bonus, RSUs, and full benefits including medical, dental, vision, and 401k match
• Summer Fridays
• Comprehensive wellness, education, and employee assistance programs

About Cambridge Mobile Telematics:

Cambridge Mobile Telematics (CMT) is the world’s largest telematics and AI company for safer mobility. Its mission is to make the world’s roads and drivers safer. The company’s AI-driven platform, DriveWell Fusion®, proactively identifies and reduces driving risk, leading to fewer crashes and injuries. To date, CMT’s technology has helped prevent over 126,000 crashes worldwide. CMT enables partners to measure risk, detect crashes, provide life-saving assistance, and streamline claims. Headquartered in Cambridge, MA, CMT operates globally with offices in Budapest, Hungary; Chennai, India; Seattle, Washington; Tokyo, Japan; and Zagreb, Croatia. Learn more at www.cmt.ai.

About Alltrna 

Alltrna is the first clinical-stage biotech company advancing tRNA medicines to address shared disease-causing mutations across many indications. The company’s initial therapeutic programs are designed to restore full-length protein production in diseases caused by premature termination codons (PTCs), collectively referred to as Stop Codon Disease, which affect approximately 10% of people with a rare genetic disease.

Alltrna’s lead program, AP003, is a chemically modified, engineered tRNA oligonucleotide encapsulated in a clinically validated, liver-directed lipid nanoparticle. AP003 is being developed for the arginine-to-TGA (Arg-TGA) PTC in patients with liver Stop Codon Disease, including phenylketonuria, organic acidemias, and urea cycle disorders. Founded in 2018 by Flagship Pioneering, Alltrna has built an integrated platform to design, optimize, and deliver engineered tRNA therapeutics. 

For more information, visit www.alltrna.com

Sr. Director Program Management & Business Operations

Position Summary:

Alltrna is seeking a talented and highly motivated Sr. Director Program Management and Business Operations, reporting to the President & CFO.  The successful candidate is a proven leader with extensive experience in leading research and early drug development program teams from research through the clinic with a particular initial focus on IND enabling and early/mid-stage clinical development. The candidate will be a member of the Company’s Leadership Team and will serve as Chief of Staff to the team to drive collaboration, cross-functional clarity, alignment and execution on key priorities and initiatives required to meet the goals of the organization.

Key Responsibilities:

Program Management:

• Work closely with the Chief Medical Officer to lead the program team for the Company’s lead program, AP003, and future programs instilling a culture of scientific rigor, open debate, collaborative teamwork, sense of urgency and accountability
• Possess a comprehensive understanding of the drug discovery process to guide program teams to define the key scientific questions, program strategy and objectives, translating these into optimal deliverables, cross-functional plans, timelines and budgets
• Identify bottlenecks, risks, issues and proactively develop appropriate mitigation proposals with input from team members
• Ensure all key decisions are identified and properly assessed as to their impact and alternative scenarios developed and evaluated, where appropriate
• Work closely with finance and functional teams to develop the operational plans to support program activities with realistic timelines, budget, and resource planning and monitor performance against plans
• Interface with and drive collaboration between the various functional teams and with the Leadership Team on program-related matters.
• Be the key accountable person for communicating matters related to the programs to management including strategy, work product, updates and issues; producing the one “source of truth” for program-related topics and timelines
• Point person for alliance management and coordination, as needed
• Lead and/or manage strategic or platform development projects as required and collaborate with Chief Scientific Officer and Research Leadership Team to coordinate relevant content for quarterly business review meetings

Operations:

• Collaborate with Leadership Team in development of strategic plans, company goals, long-range planning assumptions, portfolio-level reports and analyses to support business processes and strategic discussions
• Develop and deliver impactful presentations that effectively distill complex issues to the critical points and lead to increased understanding and optimized strategic planning & decision-making

• Prepare strategic communications utilizing a clear understanding of the business strategy and issues; develop and maintain consistent, relevant content for use in executive-level communications and to further organizational and business goals

• Lead the Scientific Communications process, working with the Scientific Communications Committee

• Manage schedule, agenda, and content for Leadership Team, Board of Directors and Town Hall meetings

• Proactively seek opportunities for organizational improvements (e.g. team structure, processes, communication, etc.)

Other:

• Support CEO / LT with partnership discussions and negotiations, including background research, preparation of presentation materials, supporting diligence activities, participating in analysis of terms, etc.
• Assist in mapping competitive landscape and proactively identify potential and emerging competitive threats and opportunities
• Promote strategic discussions on external trends, competitor strategies, and potential disruptors, and translate these into strategic choices/ recommendations
• Collect insights and intelligence from a variety of sources including literature searches, reviewing analyst research, KOL and patient group interactions, etc.

Key Competencies:

• This is a highly visible leadership role that requires exceptional interpersonal and communication skills, creative thinking, and early drug development experience that allows one to recognize opportunities/challenges and modify strategy accordingly
• The individual will need to have self-confidence and poise to manage complicated programs and projects with multiple stakeholders

• The individual will need a sense of urgency and can-do attitude to develop therapies for patients with significant unmet medical needs

Minimum Qualifications:

• BS/MS Degree in a scientific discipline, ideally life science or chemistry.
• At least 15 years relevant experience in pharma or biotech drug discovery and development, as well as a comprehensive understanding of drug discovery (preclinical and clinical).
• 10+ years of Program Management experience, preferably in early-stage drug discovery and development.
• Experience in the development of advanced therapies to treat rare genetic disease is a plus
• Demonstrated experience leading cross-functional teams; strong interpersonal and communication skills
• Scientific curiosity and passion for discovering new, innovative medicines.
• Openness to embrace new technologies and digital approaches in drug discovery
• Proven track record in driving successful, collaborative drug discovery teams.

The salary range for this role is $213,000 - $280,500. Compensation for the role will depend on a number of factors, including a candidate’s qualifications, skills, competencies, and experience. Alltrna currently offers healthcare coverage, annual incentive program, retirement benefits and a broad range of other benefits. Compensation and benefits information is based on Alltrna's good faith estimate as of the date of publication and may be modified in the future.

About Alltrna 

Alltrna is the first clinical-stage biotech company advancing tRNA medicines to address shared disease-causing mutations across many indications. The company’s initial therapeutic programs are designed to restore full-length protein production in diseases caused by premature termination codons (PTCs), collectively referred to as Stop Codon Disease, which affect approximately 10% of people with a rare genetic disease.

Alltrna’s lead program, AP003, is a chemically modified, engineered tRNA oligonucleotide encapsulated in a clinically validated, liver-directed lipid nanoparticle. AP003 is being developed for the arginine-to-TGA (Arg-TGA) PTC in patients with liver Stop Codon Disease, including phenylketonuria, organic acidemias, and urea cycle disorders. Founded in 2018 by Flagship Pioneering, Alltrna has built an integrated platform to design, optimize, and deliver engineered tRNA therapeutics. 

For more information, visit www.alltrna.com

Sr. Director Program Management & Business Operations

Position Summary:

Alltrna is seeking a talented and highly motivated Sr. Director Program Management and Business Operations, reporting to the President & CFO.  The successful candidate is a proven leader with extensive experience in leading research and early drug development program teams from research through the clinic with a particular initial focus on IND enabling and early/mid-stage clinical development. The candidate will be a member of the Company’s Leadership Team and will serve as Chief of Staff to the team to drive collaboration, cross-functional clarity, alignment and execution on key priorities and initiatives required to meet the goals of the organization.

Key Responsibilities:

Program Management:

• Work closely with the Chief Medical Officer to lead the program team for the Company’s lead program, AP003, and future programs instilling a culture of scientific rigor, open debate, collaborative teamwork, sense of urgency and accountability
• Possess a comprehensive understanding of the drug discovery process to guide program teams to define the key scientific questions, program strategy and objectives, translating these into optimal deliverables, cross-functional plans, timelines and budgets
• Identify bottlenecks, risks, issues and proactively develop appropriate mitigation proposals with input from team members
• Ensure all key decisions are identified and properly assessed as to their impact and alternative scenarios developed and evaluated, where appropriate
• Work closely with finance and functional teams to develop the operational plans to support program activities with realistic timelines, budget, and resource planning and monitor performance against plans
• Interface with and drive collaboration between the various functional teams and with the Leadership Team on program-related matters.
• Be the key accountable person for communicating matters related to the programs to management including strategy, work product, updates and issues; producing the one “source of truth” for program-related topics and timelines
• Point person for alliance management and coordination, as needed
• Lead and/or manage strategic or platform development projects as required and collaborate with Chief Scientific Officer and Research Leadership Team to coordinate relevant content for quarterly business review meetings

Operations:

• Collaborate with Leadership Team in development of strategic plans, company goals, long-range planning assumptions, portfolio-level reports and analyses to support business processes and strategic discussions
• Develop and deliver impactful presentations that effectively distill complex issues to the critical points and lead to increased understanding and optimized strategic planning & decision-making

• Prepare strategic communications utilizing a clear understanding of the business strategy and issues; develop and maintain consistent, relevant content for use in executive-level communications and to further organizational and business goals

• Lead the Scientific Communications process, working with the Scientific Communications Committee

• Manage schedule, agenda, and content for Leadership Team, Board of Directors and Town Hall meetings

• Proactively seek opportunities for organizational improvements (e.g. team structure, processes, communication, etc.)

Other:

• Support CEO / LT with partnership discussions and negotiations, including background research, preparation of presentation materials, supporting diligence activities, participating in analysis of terms, etc.
• Assist in mapping competitive landscape and proactively identify potential and emerging competitive threats and opportunities
• Promote strategic discussions on external trends, competitor strategies, and potential disruptors, and translate these into strategic choices/ recommendations
• Collect insights and intelligence from a variety of sources including literature searches, reviewing analyst research, KOL and patient group interactions, etc.

Key Competencies:

• This is a highly visible leadership role that requires exceptional interpersonal and communication skills, creative thinking, and early drug development experience that allows one to recognize opportunities/challenges and modify strategy accordingly
• The individual will need to have self-confidence and poise to manage complicated programs and projects with multiple stakeholders

• The individual will need a sense of urgency and can-do attitude to develop therapies for patients with significant unmet medical needs

Minimum Qualifications:

• BS/MS Degree in a scientific discipline, ideally life science or chemistry.
• At least 15 years relevant experience in pharma or biotech drug discovery and development, as well as a comprehensive understanding of drug discovery (preclinical and clinical).
• 10+ years of Program Management experience, preferably in early-stage drug discovery and development.
• Experience in the development of advanced therapies to treat rare genetic disease is a plus
• Demonstrated experience leading cross-functional teams; strong interpersonal and communication skills
• Scientific curiosity and passion for discovering new, innovative medicines.
• Openness to embrace new technologies and digital approaches in drug discovery
• Proven track record in driving successful, collaborative drug discovery teams.

The salary range for this role is $213,000 - $280,500. Compensation for the role will depend on a number of factors, including a candidate’s qualifications, skills, competencies, and experience. Alltrna currently offers healthcare coverage, annual incentive program, retirement benefits and a broad range of other benefits. Compensation and benefits information is based on Alltrna's good faith estimate as of the date of publication and may be modified in the future.

We are seeking an experienced Business Development Specialist to identify, pursue, and capture new business opportunities within the DoD and the Intelligence Community. The successful candidate will have a strong background in business development and a proven track record of winning new S&T programs. This role requires exceptional communication skills, strategic thinking, and the ability to build relationships with customers. You will partner with Portfolio Leads, Chief Engineers, Business Development, Contracts, Proposal, and Capture teams to bring operationally impactful and technically captivating programs to MORSE.

Responsibilities:

• Execute MORSE's business development strategy aimed at expanding our presence within the DoD and the intelligence community.

• Identify potential business opportunities and work collaboratively to develop compelling proposals that highlight our unique value proposition.

• Build and maintain relationships with key decision-makers within the DoD and the intelligence community, including program managers, acquisition officials, and other stakeholders.

• Collaborate with cross-functional teams, including engineering, sales, and marketing, to ensure effective capture, proposals, and delivery of new programs.

• Gather and analyze market intelligence on industry trends, competitor activity, and customer needs to support business development efforts and identify new business opportunities.

• Stay abreast of emerging trends and technologies relevant to our product lines and identify opportunities for growth and expansion.

Requirements:

• Bachelor's degree in a related field (e.g., business administration, engineering, computer science).

• 2-5 years of experience in business development, preferably within the DoD or the intelligence community.

• Experience selling in technical domains such as artificial intelligence, software, or related areas is highly desired.

• Knowledge of DARPA, the US Army, Air Force, Navy and other organizations in the Intelligence Community or Dept. of Defense is highly desired.

• Proven track record of success in winning new programs and growing revenue through business development initiatives.

• Strong understanding of the DoD and intelligence community acquisition processes, including the Federal Acquisition Regulation (FAR) and Defense Federal Acquisition Regulation Supplement (DFARS).

• Excellent communication skills, both written and verbal, with the ability to articulate complex ideas simply and persuasively.

• Familiarity with greenfield business development and the ability to operate effectively in fast-paced environments.

We are seeking an experienced Business Development Specialist to identify, pursue, and capture new business opportunities within the DoD and the Intelligence Community. The successful candidate will have a strong background in business development and a proven track record of winning new S&T programs. This role requires exceptional communication skills, strategic thinking, and the ability to build relationships with customers. You will partner with Portfolio Leads, Chief Engineers, Business Development, Contracts, Proposal, and Capture teams to bring operationally impactful and technically captivating programs to MORSE.

Responsibilities:

• Execute MORSE's business development strategy aimed at expanding our presence within the DoD and the intelligence community.

• Identify potential business opportunities and work collaboratively to develop compelling proposals that highlight our unique value proposition.

• Build and maintain relationships with key decision-makers within the DoD and the intelligence community, including program managers, acquisition officials, and other stakeholders.

• Collaborate with cross-functional teams, including engineering, sales, and marketing, to ensure effective capture, proposals, and delivery of new programs.

• Gather and analyze market intelligence on industry trends, competitor activity, and customer needs to support business development efforts and identify new business opportunities.

• Stay abreast of emerging trends and technologies relevant to our product lines and identify opportunities for growth and expansion.

Requirements:

• Bachelor's degree in a related field (e.g., business administration, engineering, computer science).

• 2-5 years of experience in business development, preferably within the DoD or the intelligence community.

• Experience selling in technical domains such as artificial intelligence, software, or related areas is highly desired.

• Knowledge of DARPA, the US Army, Air Force, Navy and other organizations in the Intelligence Community or Dept. of Defense is highly desired.

• Proven track record of success in winning new programs and growing revenue through business development initiatives.

• Strong understanding of the DoD and intelligence community acquisition processes, including the Federal Acquisition Regulation (FAR) and Defense Federal Acquisition Regulation Supplement (DFARS).

• Excellent communication skills, both written and verbal, with the ability to articulate complex ideas simply and persuasively.

• Familiarity with greenfield business development and the ability to operate effectively in fast-paced environments.

As a Chief Engineer (CE) at MORSE, you play a technical, strategic, programmatic, and management role driving our programs, people, and path forward. You will spearhead technical vision, work with customers to plot out the future efforts, and guide a team to execute. As a Chief Engineer - Battle Management, you will lead the design and development of mission-critical web and mobile applications that fuse complex data, enhance situational awareness, and accelerate the entire decision-making cycle—from planning to execution. 

 Responsibilities: 

• Define and champion the technical vision for our Battle Management systems, creating a roadmap that integrates advanced software architecture, data fusion, and intelligent user interfaces.

• Lead Agile, multi-disciplinary teams of 5-50+ Aerospace Engineers, Software Engineers, Mobile Developers, Human-Computer Interaction Engineers, and Cloud Engineers.

• Lead technical strategy for the development of intuitive software applications that make complex data readily available and actionable for warfighters in high-stakes environments with care for effective user experiences (UX) 

• Manage program execution, ensuring schedule and budget adherence, and overseeing successful program delivery.

• Act as a primary technical liaison with government customers and industry partners, translating their strategic needs into actionable, cutting-edge R&D programs.

• Proactively identify and shape new opportunities, lead technical proposal efforts, and own the capture process to expand MORSE's impact and portfolio in Battle Management, Command and Control (C2), and Mission Planning.

Requirements:

• US Citizenship and ability to obtain and maintain a Security Clearance. Active Secret, Top Secret, or TS/SCI is preferred. 

• A master's degree or PhD in a relevant discipline (e.g., Systems Engineering, Computer Science, Aerospace Engineering, Physics) or equivalent experience.

• 10+ years of experience leading technical teams, with a proven track record of designing and delivering complex, software-intensive systems for the defense or aerospace industry.

• Deep, hands-on experience designing architectures for complex, real-time distributed systems, such as Command and Control (C2), mission planning, or large-scale situational awareness platforms.

  Strong domain knowledge in one or more of the following: sensor fusion, mission planning, electronic warfare, or air/space operations

• Demonstrated understanding of underlying physical principles relevant to the domain (e.g., kinematics, sensor physics, RF propagation) and experience incorporating physical models into software systems.

• Proven leadership in modern software development, including service-oriented architectures, event-driven systems, and building applications for real-time data visualization.

• Proven leadership skills, with a track record of successfully managing high-performing technical teams.

• Proven experience in business development and program capture within the DoD or IC, including leading technical volumes for proposals and shaping customer requirements.

• Strong analytical and problem-solving abilities, with the capacity to absorb complex technical information quickly.

• Excellent written and verbal communication skills, with the ability to present technical information clearly and persuasively to both technical and non-technical audiences.

MORSE is searching for a Lead Data Scientist with expertise in data analysis, data science, and algorithm development in one or more of a variety of fields including visual classification, big data, natural language processing, machine translation, time sequenced data, and advanced metrics. You will lead teams and strategy for Algorithm Test and Evaluation (T&E) of AI and machine learning models and algorithms to give national security customers insights into the capabilities of applying AI to solve real world problems.

Responsibilities:

• Define goals and expectations for algorithm T&E performance

• Research artificial intelligence data splitting, metrics, and T&E methodology

• Lead strategy and coordination with algorithm development vendors

• Work with customers, stakeholders, and other vendors to present concepts, analyses, and test results

• Present a path forward and solutions to solve complex data problems

• Work with MORSE’s current team of engineers and scientists to transition algorithms to software applications and real-time embedded systems.

Requirements:

• US CITIZENSHIP REQUIRED and an Active Top Secret U.S. Security Clearance with SCI eligibility (TS/SCI) 

• Masters or Ph.D in Data Science, Computer Science, Engineering, Applied Mathematics, Physics, Physical or Biological Sciences or a related field

• 7+ years of experience in Data Science, Artificial Intelligence, or Machine Learning

• Expertise in artificial intelligence, machine learning, and data science 

• Experience in algorithm development and testing

• Excellent communication and presentation skills

• Self-starter and driven

• Ability to be onsite 4-5 days/week 

MORSE Corp is seeking a Technical Recruiter to join our Talent Acquisition team in all aspects of recruiting for our growing and highly talented workforce. You will source candidates, screen, and facilitate the recruiting process for high-caliber engineering reqs in a broad set of technical domains. These domains include software engineering, data science, machine learning/AI, human factors, and aerospace. Additionally, you will help develop and optimize MORSE's recruiting strategy, to include skill-need discovery, sourcing methods, employer branding, university/student engagement, and screening techniques.

RESPONSIBILITIES

• Partner with hiring managers across our teams and programs to identify talent needs and suitable candidates for software, data science, and engineering roles 

• Utilize outbound sourcing strategies to find talented candidates from entry to executive level

• Own the full cycle recruiting process from initial contract (sourcing or application) to onboarding

• Find creative ways to establish the MORSE employer brand and attract talent 

• Integrate the MORSE values into all aspects of the recruiting process

REQUIREMENTS

• US CITIZENSHIP REQUIRED 

• 1+ years of experience in technical recruiting, either corporate or agency

• Hands-on experience using recruiting and sourcing tools such as job boards, social media, applicant tracking systems (Greenhouse) search engines, and other active methods of reaching active and passive candidates

• Demonstrated capability to source top technical talent spanning the range from entry-level to executive

• Ability to screen candidates and assess technical and corporate fit

• Outstanding organizational, time management, and process management skills and exceptional attention to detail

• Proven interpersonal skills and experience building strong relationships with candidates

The Role:

Reporting to the Head of Nuvalent Medical Affairs, the Senior Director of Medical Affairs Operations will serve as a strategic thought partner to the Head of Medical Affairs and the Medical Affairs Leadership Team (MALT). This role provides operational leadership, discipline, and alignment across Medical Affairs, ensuring that objectives, processes, and resources are optimized to deliver impact at scale. The incumbent will drive operational excellence, enable cross-functional collaboration, and oversee field operations, insights, and analytics to support the organization’s growth and transformation.

Responsibilities:

• Strategic Partnership & Leadership
  • Act as a trusted advisor to the Head of Medical Affairs and MALT, shaping operational strategy and execution.
  • Drive strong cross-functional team planning and alignment (e.g. MALT, MALT/CLT, Medical Strategy, and IEGT), ensuring smooth ways of working and operational discipline, with seamless execution of strategic priorities.
• Performance Management and Launch Readiness
  • Lead KPI and objectives planning, tracking, and reporting to ensure accountability and transparency.
  • Develop dashboards and reporting frameworks to provide real-time visibility into Medical Affairs performance, risks, and resource utilization; establish frameworks for measuring impact and continuous improvement.
• Operational Excellence and Continuous Improvement
  • Define and evolve ways of working within Medical Affairs, including process development, capability building, and cross-functional orchestration.
  • Drive continuous process improvement and simplification, including SOP development and refinement to ensure scalability and compliance.
• Financial Stewardship
  • Oversee budget planning, forecasting, and resource allocation to ensure fiscal discipline and strategic investment.
  • Partner with Finance to align operational spend with organizational priorities.
• Risk Management & Executive Communications
  • Identify, assess, and mitigate operational risks, ensuring proactive management and transparent escalation to leadership.
  • Craft and deliver executive communications that synthesize operational performance, risks, and strategic initiatives for senior leadership and board audiences.
• Strategic Initiatives and Capability Building
  • Support and enable key initiatives such as regional expansion, organizational transformation, and business model evolution.
  • Support Medical capability building initiatives, ensuring teams are equipped with the skills, processes, and tools to deliver impact.
• Knowledge & Communication
  • Establish central knowledge management systems to ensure accessibility and transparency of information.
  • Facilitate effective team communication and alignment across Medical Affairs and field teams.
• Field Operations & Analytics
  • Provide oversight of field operations, insights generation, and analytics to inform strategy and decision-making.
  • Ensure robust mechanisms for capturing and translating field intelligence into actionable insights.
• Team Facilitation & Culture
  • Foster a high-performance culture through facilitation, coaching, and team development.
  • Enable collaboration, accountability, and continuous learning across Medical Affairs.

Competencies Include:

• Strategic thinker with operational rigor.
• Collaborative leader who builds trust and alignment across diverse stakeholders.
• Skilled in change management and organizational transformation.
• Adept at balancing strategic priorities with tactical execution.
• Committed to fostering a culture of accountability, transparency, and innovation.

Qualifications:

• Advanced degree in life sciences, healthcare, or related field; MBA or equivalent preferred.
• 10+ years of experience in Medical Affairs, clinical development, or related operational leadership roles.
• Proven track record of leading cross-functional teams and driving operational excellence in complex organizations.
• Strong financial acumen with experience in budget management and forecasting.
• Expertise in KPI development, performance tracking, and analytics.
• Exceptional communication, facilitation, and stakeholder management skills.
• Ability to synthesize complexity into clear, actionable frameworks for executive and board-level audiences.

Additional Information:

Nuvalent is committed to fair and equitable compensation practices, aiming to provide employees with competitive total rewards packages.

The targeted salary range reflects what Nuvalent reasonably and in good faith expects to offer for this position at the time of posting, but the final salary determination may be within or outside this range based on various factors, including, but not limited to, experience, skills, education, and market factors.  The range will be reviewed regularly and is subject to change.

Nuvalent also offers a comprehensive benefit package to support our employees at each stage of their career, financial, health, and well-being journey, including medical, dental, and vision insurance, 401(k) retirement savings plan, generous paid time off (including a summer and winter company shutdown), and much more.

The Role:

Reporting to the Director, Global Regulatory Affairs, the Senior Manager, Regulatory Affairs role will integrate regulatory strategic development, submission management expertise, and hands-on execution to support the IND/CTA stage of development through NDA/MAA.

The Senior Manager, Regulatory Affairs will contribute to the development and implementation of regulatory strategy as a member of the global regulatory affairs function and clinical study team(s). This role will manage the process for preparation, submission and internal review and approval of regulatory documents, including providing technical regulatory input for global documents to streamline development.

The Senior Manager, Regulatory Affairs must be kept current, innovative, and compliant with the constant changing Health Authority requirements to facilitate regulatory processes and compliance maintenance from IND/CTAs through NDA/MAA. 

Responsibilities:

• Participates as a regulatory representative for Clinical Study Team (CST) on development programs assigned working closely with product development team (PDT) lead to develop the global regulatory strategy; work closely with regulatory operations and program management to track timelines and ensure deliverables are achieved
• As part of the regulatory clinical study team, you will support preparation, review, compilation, and execution of submissions for regulatory agencies for US and ROW (e.g., IND/CTAs, NDA/MAA, DSURs, Amendments, and Responses to Regulatory Agency Requests for Information, etc.)
• Provide regulatory guidance and support to senior regulatory affairs members on various projects, as needed, to further development programs (pediatric development planning, regulatory interactions, NDA planning)
• Ensure collaboration with and coordination of cross-functional project teams for timely execution of regulatory submissions, maintaining compliance with global regulatory standards and commitments, and providing regulatory guidance and oversight
• Support regulatory operations during the regulatory submissions handoff process, as the primary point of contact for external publishing vendors, ensuring submission packages are accurate, formatted correctly, and validated.
• Maintain the regulatory information system and ensure proper archiving, searchability, and accessibility of regulatory content including correspondence with regulatory agencies
• Manage regulatory submission processes, develop and maintain regulatory tracking tools and infrastructure, as assigned Conduct regulatory intelligence and competitive intelligence and summarize key impacts to global strategy development teams, as appropriate
• Ensure compliance with internal SOPs, regulations and applicable laws. Drafts and reviews Regulatory Affairs SOPs and work instructions and provides Regulatory feedback on other departmental SOPs, where required

Competencies Include:

• Excellent attention to detail and ability to complete efficient and detailed technical data review
• Excellent organization, communication, and multi-tasking skills
• Exceptional interpersonal skills and experience contributing to productive teams and fostering cross functional relationships
• Strong desire to contribute as a member of an engaged and collaborative cross-functional project development team

 Qualifications:

• 6-8 years of experience in Regulatory Affairs or combination of education and direct experience.
• Bachelor or advanced degree in a scientific field or equivalent work experience is required.  Master’s degree a plus.
• Proven experience in evaluation, preparation and compilation of quality dossiers in all required formats and/or experience in regulatory processes.
• Solid understanding of the e-CTD specifications for electronic submissions.
• Knowledge and practical understanding of ICH Guidelines regarding GMP/GCP, ICH Guidelines for CTD/eCTD and CDER requirements for the drug approval process.
• Previous participation in preparing and/or leading regulatory submissions (IND, CTA, NDA, etc.). Experience with preparing meeting packages is a plus.
• Experience in interpretation of regulations, guidelines and precedents related to drug development in the US and EU.
• Strong understanding of regulatory eCTD structure and clinical trial conduct and design
• Proficiency with electronic submission publishing software and document management information systems (i.e., docuBridge, Veeva Vault RIM)
• Ability to plan, prioritize and contribute to work and projects in a systematic and efficient manner with emphasis on streamlining processes

Additional Information:

Nuvalent is committed to fair and equitable compensation practices, aiming to provide employees with competitive total rewards packages.

The targeted salary range reflects what Nuvalent reasonably and in good faith expects to offer for this position at the time of posting, but the final salary determination may be within or outside this range based on various factors, including, but not limited to, experience, skills, education, and market factors.  The range will be reviewed regularly and is subject to change.

Nuvalent also offers a comprehensive benefit package to support our employees at each stage of their career, financial, health, and well-being journey, including medical, dental, and vision insurance, 401(k) retirement savings plan, generous paid time off (including a summer and winter company shutdown), and much more.

Company Summary: 

Prologue Medicines uses advances in structural predictions and large language models to functionally annotate the entire viral proteome to leverage millennia of viral evolution for the development of transformative medicines. Prologue has nominated two development candidates and is building a broad pipeline of therapeutics across several therapeutic areas. One of Prologue Medicines’ founding principles is to build an inclusive and exciting working environment that fosters personal and professional growth by ensuring that all team members contribute to and feel ownership of our scientific vision. 

Flagship Pioneering is a biotechnology company that invents and builds platform companies, each with the potential for multiple products that transform human health or sustainability. Since its launch in 2000, Flagship has originated and fostered more than 100 scientific ventures, resulting in more than $90 billion in aggregate value. Many of the companies Flagship has founded have addressed humanity’s most urgent challenges: vaccinating billions of people against COVID-19, curing intractable diseases, improving human health, preempting illness, and feeding the world by improving the resiliency and sustainability of agriculture.  

Flagship has been recognized twice on FORTUNE’s “Change the World” list, an annual ranking of companies that have made a positive social and environmental impact through activities that are part of their core business strategies, and has been twice named to Fast Company’s annual list of the World’s Most Innovative Companies. Learn more about Flagship at www.flagshippioneering.com. 

Position Summary: 

We are seeking an exceptional scientific leader to serve as VP/SVP, Biology & Translational Science, responsible for driving our discovery and early development strategy from target identification through IND and continue to support the program as needed through clinical development. This individual will integrate deep expertise in immunology, translational science and/or protein biologics to build a high-impact pipeline and ensure successful progression of programs into the clinic. The ideal candidate will have a proven ability to develop effective strategies and execution plans to advance early molecules through preclinical development to ensure emerging assets exhibit strong differentiation and possibility of success. They should have an excellent understanding of the landscape of immune-mediated diseases to help build a diversified pipeline.. The successful candidate will be an enthusiastic, goal-driven individual who participates as a strategic leader while fostering a culture of executional excellence.   

Key Responsibilities: 

Translational Science & Clinical Readiness 

• Define translational strategies to bridge preclinical findings to human studies
• Lead identification and implementation of biomarkers (PD, predictive, and safety)
• Ensure programs are designed with clinical endpoints and patient stratification in mind
• Increase probability of clinical success through mechanism-based approaches.
• In collaboration with PKPD/ QSP modeling team, develop translational frameworks for AI enabled derisking of drug development path 

Biologics Development (Hit ID to IND) 

• Lead progression of protein biologics programs from hit identification through lead optimization and IND-enabling studies
• Partner cross-functionally with discovery and development teams to build out and drive comprehensive IND strategy, including pharmacology, safety, and translational packages
• Ensure clear go/no-go decision frameworks across discovery and preclinical stages
• Proactively recognize and develop creative solutions for emerging technical and scientific issues 

Discovery Biology & Target Strategy 

• Lead target identification, evaluation, and nomination grounded in human biology and disease relevance
• Define and drive biological hypotheses aligned with company strategy, with a focus on immunology
• Oversee development of robust in vitro and in vivo models to validate targets and mechanisms
• Build and prioritize a portfolio strategy for multiple differentiated biologics programs 

Leadership & Cross-Functional Integration 

• Build, mentor and lead high-performing teams delivering across biology, pharmacology, and translational science. Identify, initiate, and manage productive collaborations with CROs, partners and academic labs as appropriate to driving projects forward and collaborate closely with clinical development, regulatory, and executive leadership
• Develop, motivate and inspire a high-performing Biology and Translational Science organization
• Serve as an enterprise leader, driving cross-functional alignment, clear decision-making, and a culture of accountability, innovation, and executional excellence.
• Serve as a key scientific voice with board members, investors, and external partners
• Foster a culture of rigor, innovation, collaborative and decisive execution 

Qualifications: 

• PhD or MD/PhD in pharmacology or biological disciplines such as immunology, cellular biology, oncology, or biochemistry, with 10+ years direct pharmaceutical experience beyond postdoctoral work 
• Deep expertise in immunology with a strong understanding of disease biology
• Proven track record advancing protein biologics from hit identification to IND
• Significant experience in target selection and nomination
• Demonstrated ability to lead cross-functional teams to drive go/no go decisions
• Excellent project management skills and the ability to effectively manage CROs and to facilitate interactions with academic labs and companies to ensure project progression.
• Demonstrated success in translational science, including biomarker strategy and IND-enabling work and direct experience in supporting IND strategy and documentation, including writing relevant pharmacology sections of INDs.
• Flexibility to dynamical adapt workplans and lead teams through changing priorities and deadlines.
• A pioneering mindset to grow a startup venture
• Prior experience working in smaller companies is highly preferred 

Leadership Profile 

• Strategic thinker with strong scientific judgment
• Ability to make high-quality decisions under uncertainty
• Skilled at balancing innovation with execution discipline
• Effective communicator with strong external presence
• Passion for building teams and developing talent 

Impact 

This role will shape the company’s scientific direction and pipeline, directly influencing the success of programs entering the clinic and ultimately improving patient outcomes. 

Flagship Pioneering and our ecosystem companies are committed to equal employment opportunity regardless of race, color, ancestry, religion, sex, national origin, sexual orientation, age, citizenship, marital status, disability, gender identity or Veteran status. 

Recruitment & Staffing Agencies: Flagship Pioneering and its affiliated Flagship Lab companies (collectively, “FSP”) do not accept unsolicited resumes from any source other than candidates. The submission of unsolicited resumes by recruitment or staffing agencies to FSP or its employees is strictly prohibited unless contacted directly by Flagship Pioneering’s internal Talent Acquisition team. Any resume submitted by an agency in the absence of a signed agreement will automatically become the property of FSP, and FSP will not owe any referral or other fees with respect thereto.

The salary range for this role is $275,000 - $340,000. Compensation for the role will depend on a number of factors, including a candidate’s qualifications, skills, competencies, and experience. Prologue Medicines, Inc. currently offers healthcare coverage, annual incentive program, retirement benefits and a broad range of other benefits. Compensation and benefits information is based on Prologue Medicines, Inc.'s good faith estimate as of the date of publication and may be modified in the future.

About the Role:

Stylus Medicine is seeking an intellectually curious and creative Director, who will serve as a key scientific leader on our Platform team, owning the computational strategy that drives large serine recombinase (LSR) engineering and clinical translation. This role sits at the intersection of protein engineering, multi-omics analysis, and AI/ML-driven design and will lead a high-impact team spanning NGS and computational biology while driving the analytical infrastructure and predictive capabilities needed to advance our proprietary LSR platform from discovery through translation.

Key Responsibilities & Accountabilities:

• Lead and develop a team of NGS and computational biology scientists, setting technical direction, mentoring team members, and fostering a collaborative, high-performance culture
• Lead computational efforts to design and optimize LSRs and related genome engineering proteins for genetic medicine applications, integrating sequence-function, structure-function, and protein-DNA interaction datasets to guide engineering campaigns
• Lead analysis of NGS data from LSR experiments — including amplicon sequencing, WGS, hybrid capture, and long-read sequencing — to quantify on-target efficiency and genome-wide specificity
• Build, apply, and critically evaluate predictive and generative models for protein variant and library design — including rigorous benchmarking of AI/ML approaches such as protein language models, structure prediction tools, and generative design frameworks
• Integrate proprietary screening data with public evolutionary and structural datasets to prioritize variants and identify engineering levers for activity, specificity, and developability
• Oversee the design, implementation, and deployment of robust, scalable computational pipelines for multi-omics data analysis, ensuring accuracy, reproducibility, and maintainability
• Provide scientific input into platform strategy, translating computational insights into actionable directions for the broader team
• Partner closely with the Screening, Genome Engineering, and NGS teams to design experiments, interpret complex datasets, and refine engineering hypotheses
• Contribute to patent filings, regulatory submissions, and publications

Qualifications & Skills:

• PhD in Computational Biology, Bioinformatics, Protein Engineering, Machine Learning or a related quantitative discipline, with 10+ years or Master’s with 14+ years of industry experience
• Demonstrated research in protein modeling, protein design, or computational biology through publications, preprints, or equivalent industry contributions
• Hands-on experience applying AI/ML methods to protein variant and library design, including protein language models, structure prediction, and generative design approaches (e.g., AlphaFold2/3, RFdiffusion, ProteinMPNN, ESM)
• Expert-level proficiency in Python and/or R, with deep familiarity with data science libraries (e.g., Pandas, NumPy, Bioconductor, SciPy, PyTorch, or JAX)
• Experience with cloud computing platforms and workflow management systems
• Excellent communication and documentation skills, with a track record of effective collaboration in fast-paced, interdisciplinary environments

Pay Range; $245,000 - $265,000

Coordinator, Development & Program Operations

Harvard Hillel

Role Overview

The mission of Harvard Hillel is to be a Jewish home, both physical and virtual, on the Harvard University campus.  Harvard Hillel welcomes all students to experience the variety of Jewish identity, tradition, practice, values, culture, and community and to inspire and enable connections on campus and beyond. Harvard Hillel (HH) students find meaningful connections and friendship while engaging in unique opportunities to make Jewish thought and culture integral in the life of the University. 

The Coordinator, Development & Program Operations (the Coordinator) serves as a hub of information, pro-active project management, and administrative expertise for Harvard Hillel’s fundraising and student-facing program teams. The Coordinator works closely with Central Services to plan and implement activities shared between Development, Program, and Operations.  

The Coordinator’s primary responsibilities are to plan, coordinate, and communicate upcoming activities of the Development and Program departments, and to coordinate and communicate upcoming shared projects effectively across departments. The Coordinator engages across the organization to play an active role leading and supporting high-impact projects.

As the organization’s needs evolve, and the Coordinator develops their experience and skills, it is anticipated that the Coordinator will be mentored and trained into a donor-facing Development role.

What You’ll Do

Development Operations

• Support fundraising success and learn about fundraising strategy.
• Maintain the fundraising management database and related online systems, as the key tools of development operations, to ensure effective stewardship of existing constituents.
• Actively manage the fundraising management system (Donor Perfect), ensuring clean records, data, outreach lists.
• Actively manage the communication tools (Constant Contact and HH website), ensuring effective engagement of audience segments.
• Work closely with colleagues across departments, including Operations, central services, and finance, to record and track information and materials for pledges, gifts, donations, grants and contracts routinely scanning, tracking, communicating, and acknowledging as needed between departments.
• Project manage a donor records project, establishing an implementation timeline and metrics of success, to verify the accuracy, completeness, and confidentiality of donor records.
• Maintain relationships with donors, customers, and vendors to bring forward payments, billing, contracting, and trouble-shoot inquiries as needed.

Development Engagement

• Plan and implement future fundraising activities, guided by research and engagement of prospective donors, funders, and other constituents of Harvard Hillel.
• Conduct research to identify prospective donors, corporate funders, and private foundations.
• Coordinate fundraising appeals across social media, email, website, and print.
• Track gifts in Donor Perfect; generate and send acknowledgements for pledges, gifts, donations, and other payments.
• Engage with Harvard Hillel Board of Directors and staff to steward gifts and pledges.
• Engage with colleagues across departments to coordinate and implement fundraising events.

Program Operations

• Manage HEART, the Harvard Hillel student engagement database, guided by programming goals to engage students throughout the academic year.
• Design and manage forms across multiple tools to support student engagement through event registrations, student surveys, and payments for student trips.
• Support student-led travel and logistics as needed, working closely with the Program Director, student leaders, and others as needed.
• Work closely with colleagues who are planning and coordinating program-related events. Engage in shared support as needed for High Holidays and on-site events.
• Other duties as assigned.

What You’ve Accomplished

• Open and willing to engage in conversations about religion, and to learn about Judaism and Israel in a way that inspires stakeholders to invest in our work.
• No less than 2 years of experience in a dynamic position in a non-profit organization.
• Highly collaborative problem-solver with curiosity to engage across teams both inside and outside of Hillel to successfully manage competing priorities.  
• A self-starter, adept at project management tools and practices, time-management and effective communications both verbally and in writing.
• Highly comfort working effectively both independently and in teams to meet goals and deadlines.
• Skilled at creative, data driven, presentations.
• Intermediate knowledge of Microsoft Office tools; comfortable in both Powerpoint and Canva.
• Highly empathetic with a positive attitude and sense of humor.
• Bachelor's degree or equivalent.

What You’ll Receive

• Salary range is ~$60,000 commensurate with experience. 
• A comprehensive benefits package, including health insurance, retirement plan, Life, AD&D and Long-Term Disability (LTD) insurances, Flexible Spending accounts, generous vacation/sick time, and parental leave.
• Great professional development, mentoring, and skill building opportunities.
• A unique opportunity to develop and promote a vibrant, pluralistic Jewish community at Harvard Hillel

About Harvard Hillel 

Harvard Hillel offers staff a unique opportunity to serve, work, and grow with a remarkable community of young adults, lay leaders, and colleagues. Harvard Hillel is an equal opportunity employers. We are committed to creating an accepting and inclusive environment for all. 

Harvard Hillel is affiliated with Hillel International. Hillel International enriches the lives of Jewish students so they may enrich the Jewish people and the world and envisions a world where every student is inspired to make an enduring commitment to Jewish life, learning and Israel.

Director of Operations and Strategy

Harvard Hillel

About the Role

Harvard Hillel seeks an exceptional founding professional to institutionalize and sustain The Camel, a highly successful Harvard- and MIT–student-led initiative that has emerged as one of the most dynamic platforms for Jewish, Israeli, and cross-cultural engagement on elite campuses. 

Launched in 2024 as a student startup, The Camel has been conceived, built, and led by students—and has rapidly grown into a high-impact initiative backed by leading figures in business and Jewish philanthropy. In its first year, The Camel welcomed nearly 2,000 students (approximately half non-Jewish) to more than 20 events and culminated in a three-day Hackathon connecting elite Israeli innovators and IDF veterans with Harvard and MIT students.

This role is designed to institutionalize and provide continuity to The Camel while preserving, cultivating, and strengthening its student-led DNA. The Director will serve as the professional anchor—ensuring financial rigor, operational excellence, donor stewardship, and long-term sustainability—while fostering student leadership development, governance, and succession so that The Camel continues to thrive as a student-driven movement.

The Director will work in close partnership with student leaders and maintain a dotted-line reporting relationship to the Camel Student Board, supporting their vision and empowering them to drive growth, programming, and culture.

This is a founding leadership role at a pivotal moment, shaping how a successful student startup matures into a durable, multi-campus, and international institution.

Position Overview

• Title: Director of Operations and Strategy
• Status: Full-time (40 hours/week; flexible as required by programming)
• Reports to: Director of Development 
• Dotted-line relationship: Camel Student Board & Executive Director

Key Responsibilities

Institutional Leadership & Continuity for The Camel

• Serve as the founding professional leader responsible for institutionalizing The Camel while preserving its student-led ethos.
• Partner closely with the Camel Student Board  and founders to translate student vision into executable, sustainable strategy
• Build and maintain the operational, financial, and governance infrastructure that allows student leadership to succeed year after year
• Implement student leadership succession frameworks, ensuring continuity across graduating classes
• Act as steward of institutional memory, systems, and best practices as student leadership turns over
• Serve as the operational and administrative interface between student leadership, Harvard Hillel administration, and external partners, while supporting student leaders in maintaining and strengthening those relationships.

Financial Management, Operations & Stakeholder Stewardship 

• Establish financial systems and Implement financial operations for The Camel, including budgeting, expense tracking, accounts payable/receivable, and reporting, in coordination with student Board
• Manage six-figure to seven-figure program budgets with transparency and rigor
• Support the execution of 3+ complex, high-production events per month, working hand-in-hand with student leaders
• Serve as primary staff liaison to donors, advisory board members, speakers, and strategic partners
• Prepare financial and impact reports for student leadership, advisory boards, and philanthropic stakeholders
• Coordinate advisory board meetings and donor briefings
• Oversee gift processing, vendor payments, and donor acknowledgments in compliance with nonprofit and university systems
• Track engagement metrics and outcomes to support fundraising and strategic growth

Required Qualifications

• Bachelor’s degree and 3–7 years of progressively responsible experience in operations, finance, nonprofit management, or program leadership
• Demonstrated experience managing budgets and financial reporting and systems
• Strong comfort partnering with student leaders while providing professional structure and accountability
• Exceptional organizational and interpersonal skills
• Experience working with high-level stakeholders, donors, or advisory boards
• Ability to thrive in fast-paced, high-visibility environments
• Willingness to work flexible hours

Compensation & Benefits

• Salary range: $75,000 – $85,000, commensurate with experience
• Comprehensive benefits package including health insurance, retirement plan, and generous paid time off
• Unparalleled access to influential entrepreneurs, investors, and philanthropists
• Opportunity to help institutionalize a nationally scalable, student-driven model

About Harvard Hillel & The Camel

Harvard Hillel is a Jewish home that welcomes all students to explore Jewish identity, culture, and community at one of the world’s most influential universities.

The Camel is a student-founded and student-led initiative redefining Jewish and Israel engagement through inspiration, innovation, and opportunity.

Harvard Hillel is affiliated with Hillel International. Hillel International enriches the lives of Jewish students so they may enrich the Jewish people and the world, and envisions a world where every student is inspired to make an enduring commitment to Jewish life, learning and Israel.

The Role:

Reporting to the Senior Director of Pharmacovigilance (PV) Operations, the Associate Director of PV Operations will provide vendor oversight and review of ICSR processing. They will ensure compliance and adherence to Safety processes and SOPs as well as manage and analyze data from the Global Safety Database. This SME will be the primary point of contact for quality oversight of the case processing vendor. They will work in close collaboration with PV physicians, PV scientists, and PV Excellence on operational safety and case quality issues The role will expand and evolve in line with Nuvalent’s expansion as we approach potential market authorization.

Responsibilities:

• Manage and support the relationship with safety vendor(s) to ensure effectiveness, quality and compliance of all outsourced activities.
• Provide Sponsor oversight of operational safety responsibilities, including the timely and accurate execution of the processes defined within the applicable Safety Management plans.
• Monitor performance (metrics, other reports) of the safety vendor and the quality output of the ICSRs; provide appropriate feedback and training.
• Monitor key performance indicators of case processing and present findings to Head of PV and cross-functional stakeholders.
• Participate in daily management, operational oversight and execution of operational safety tasks for assigned Nuvalent clinical programs.
• As needed. review incoming adverse event reports and communications from vendors to determine action required and ensure prompt review, follow-up, and timely submission of expedited safety reports.
• Oversee case workflow (case receipt through submission) between safety vendor and Nuvalent Pharmacovigilance team.
• Ensure safety case queries are resolved as per defined processes (interfacing with safety physicians, clinical operations team, other cross-functional teams within Nuvalent, and clinical vendors, as required) and facilitate case closure within required timelines.
• Serve as PV operations SME on safety reporting processes according to study protocol.
• Participate in the development and maintenance of SOPs, forms, plans, systems, and guidance documents to ensure compliance with all applicable regulatory requirements or guidelines, GVP and industry best practices.
• Serve as resource and contact for other functions within the company for pharmacovigilance
• operational activities.
• Serve as Pharmacovigilance representative for the operational aspects of the SAE reconciliation.

Competencies Include:

• Excellent written and verbal communication skills.
• Demonstrated communications expertise with the ability to articulate, influence, and work successfully with internal/external stakeholders and within a matrixed environment.
• Ability to plan and handle multiple responsibilities simultaneously and still meet high quality and timeliness standards under pressure.
• Demonstrated contribution to strategy and innovation. Contributes to or leads actionable strategies.
• Demonstrated project management and prioritization capabilities.

Qualifications:

• Bachelor’s degree in nursing, RN, Pharmacy, Pharm D., or other relevant health-care related field.
• 8-10 years of experience in a biotech/pharma company.
• Direct experience managing relationships with service providers or external business partners
• Clinical Development experience.
• Strong knowledge of current and emerging regulatory requirements including EMA GVP Modules, FDA IND and NDA reporting requirements, ICH, CIOMS
• Ability to interpret and follow regulatory guidelines.
• Proven knowledge of Good Documentation Practices and cGXPs.
• Basic knowledge of MedDRA coding.
• Experience in ICSR case-processing and reporting.
• Experience working in and with safety databases.

Additional Information:

Nuvalent is committed to fair and equitable compensation practices, aiming to provide employees with competitive total rewards packages.

The targeted salary range reflects what Nuvalent reasonably and in good faith expects to offer for this position at the time of posting, but the final salary determination may be within or outside this range based on various factors, including, but not limited to, experience, skills, education, and market factors.  The range will be reviewed regularly and is subject to change.

Nuvalent also offers a comprehensive benefit package to support our employees at each stage of their career, financial, health, and well-being journey, including medical, dental, and vision insurance, 401(k) retirement savings plan, generous paid time off (including a summer and winter company shutdown), and much more.

Flagship Pioneering is a scientific innovation engine that invents and builds companies that change the world. We bring together the greatest scientific minds with entrepreneurial company builders and assemble the capital to allow them to take courageous leaps in human health, sustainability, and beyond. 

What sets Flagship apart is our ability to advance biotechnology by uniting life science innovation, company creation, and capital investment under one roof in a way that is largely without precedent. Our team of scientists, entrepreneurial leaders, and professional capital managers are each aligned around an institutionalized process that enables us to innovate and create breakthroughs for the benefit of people and planet.

Many of the companies Flagship has founded have addressed humanity’s most urgent challenges: vaccinating billions of people against COVID-19, curing intractable diseases, improving human health, preempting illness, and feeding the world by improving the resiliency and sustainability of agriculture.

Flagship has been recognized twice on FORTUNE’s “Change the World” list, an annual ranking of companies that have made a positive social and environmental impact through activities that are part of their core business strategies, and has been named four times to Fast Company’s annual list of the World’s Most Innovative Companies.

Position Overview

Flagship Pioneering is seeking an experienced and strategic Vice President or Senior Vice President, Total Rewards and People Operations to lead the design, management, and evolution of Total Rewards programs and key people infrastructure across our ecosystem. The scope of this role spans compensation, executive compensation, equity, benefits, people operations, and people analytics for Flagship and its portfolio of companies.

This is a highly visible leadership role requiring deep expertise in compensation strategy and private-company equity, as well as the ability to operate effectively across a complex, fast-paced, and highly matrixed environment. The ideal candidate will bring strong executive presence, sound judgment, and the ability to translate business strategy into scalable people programs that support growth, innovation, and organizational effectiveness.

This leader will oversee an established team across Compensation, Benefits, People Operations, and People Analytics, and will be expected to shape a modern, market-relevant Total Rewards philosophy, refine equity and incentive structures, advance benefits strategy, and drive people insights that support executive decision-making.

Key Responsibilities

Total Rewards Strategy and Leadership

• Lead the strategy, design, and ongoing evolution of Flagship’s global Total Rewards philosophy across compensation, executive compensation, equity, benefits, and other reward programs. 
• Serve as the principal architect of rewards strategy, recommending program direction to senior leadership and ensuring alignment with business priorities, talent strategy, and financial objectives. 
• Develop and refine salary structures, incentive frameworks, equity guidelines, and market positioning approaches across a global footprint. 
• Oversee job architecture and leveling governance in support of internal equity, talent management, and scalable compensation decision-making. 
• Guide annual compensation planning processes, including merit, bonus, promotion, and other pay actions, in partnership with HR, Finance, and business leadership. 
• Partner closely with Talent Acquisition and HR Business Partners on executive and broad-based offer strategy, market competitiveness, and internal equity. 
• Lead the continued evolution of executive compensation and broad-based equity strategy across Flagship and applicable portfolio companies. 

Equity and Incentive Design

• Provide strategic leadership for complex equity and long-term incentive programs, including private-company equity structures and alternative long-term incentive constructs. 
• Oversee equity strategy, governance, and operational execution through the team, ensuring strong program design and scalable administration. 
• Partner with senior leadership on the design and refinement of incentive and ownership frameworks that support attraction, retention, and long-term value creation. 
• Bring familiarity with innovative and non-traditional compensation approaches, including profits interests, carried interest, and related long-term incentive structures. 

Benefits Strategy

• Lead benefits strategy across health and welfare, retirement, leave, and ancillary programs, ensuring programs remain competitive, sustainable, and aligned with organizational values and workforce needs. 
• Partner with the Benefits leader and external advisors to evaluate plan design, funding, market trends, vendor performance, and evolving regulatory requirements. 
• Support harmonization and modernization of benefits strategy where appropriate across a diverse and growing ecosystem. 

People Operations

• Oversee key People Operations functions, including onboarding, offboarding, employee lifecycle processes, policy administration, compliance workflows, service delivery, and operational process excellence. 
• Ensure people processes are scalable, well-governed, and designed to support a high-quality employee and manager experience. 
• Partner effectively across HR, Payroll, IT, Legal, and Finance to improve operational efficiency and strengthen people-related infrastructure. 
• Provide leadership on HR compliance, as well as compensation- and benefits-related compliance considerations, in partnership with internal and external experts as appropriate. 

People Analytics

• Lead the People Analytics agenda, with an emphasis on generating insights that support executive decision-making across workforce planning, hiring, retention, compensation, and organizational effectiveness. 
• Oversee dashboards, reporting, and analytical frameworks that inform leaders including the CEO and CFO. 
• Translate data and analysis into actionable recommendations in partnership with HR Business Partners and business leaders. 
• Advance a thoughtful, increasingly sophisticated analytics capability that supports better people decisions across Flagship and the broader ecosystem. 

Portfolio Company Partnership

• Advise and support portfolio company leaders on Total Rewards strategy, with involvement calibrated to company stage, maturity, and business need. 
• Tailor rewards frameworks and guidance for a range of company stages while maintaining sound governance and alignment with broader talent and value creation goals. 
• Present recommendations and insights to portfolio company leadership and boards as needed. 

Leadership and Team Development

• Lead, develop, and inspire a multi-functional team spanning Compensation, Benefits, People Operations, and People Analytics. 
• Foster strong collaboration across functional teams and help continue building a high-performing, service-oriented, and strategically focused organization.
• Manage external consultants, brokers, survey providers, and other key vendors in support of rewards strategy and operational excellence. 

Qualifications

• 15+ years of progressive experience in Total Rewards, with significant depth in compensation strategy and experience leading broad, multi-functional teams. 
• Deep expertise in compensation design, market benchmarking, executive compensation, incentive strategy, and private-company equity. 
• Strong familiarity with alternative long-term incentive structures, including profits interests, carried interest, and other innovative ownership or reward constructs. 
• Experience leading or advising on benefits strategy, including health and welfare, retirement, leave, and ancillary offerings. 
• Experience overseeing or partnering closely with People Operations and People Analytics functions in complex organizations. 
• Demonstrated success operating in high-growth, founder-led, venture-backed, private equity, or similarly dynamic business environments. 
• Experience supporting global workforces and navigating matrixed organizations with multiple stakeholders and business models. 
• Strong executive presence with the ability to influence senior leaders, present compelling recommendations, and operate as a trusted advisor. 
• Proven ability to translate data and market insights into practical, business-relevant decisions and action plans. 
• Experience working with boards, founders, and senior executive stakeholders preferred. 
• Prior life sciences or biotechnology experience preferred, but not required. 

Why Join Flagship Pioneering?

This is a rare opportunity to play a critical role in shaping how a highly innovative organization rewards, supports, and scales exceptional talent. As Senior Vice President, Total Rewards and People Operations, you will operate at the intersection of business strategy, organizational design, and cutting-edge science, helping to build and evolve the people infrastructure that supports transformative work in human health and sustainability.

At Flagship, we recognize there is no perfect candidate. If you have some of the experience listed above but not all, please apply anyway. Experience comes in many forms, skills are transferable, and passion goes a long way. We are dedicated to building diverse and inclusive teams and look forward to learning more about your unique background.

Recruitment & Staffing Agencies: Flagship Pioneering and its affiliated Flagship Lab companies (collectively, “FSP”) do not accept unsolicited resumes from any source other than candidates. The submission of unsolicited resumes by recruitment or staffing agencies to FSP or its employees is strictly prohibited unless contacted directly by Flagship Pioneering’s internal Talent Acquisition team. Any resume submitted by an agency in the absence of a signed agreement will automatically become the property of FSP, and FSP will not owe any referral or other fees with respect thereto.

#LI-NM1

The salary range for this role is $300,000 - $400,000. Compensation for the role will depend on a number of factors, including a candidate’s qualifications, skills, competencies, and experience. Flagship Pioneering currently offers healthcare coverage, annual incentive program, retirement benefits and a broad range of other benefits. Compensation and benefits information is based on Flagship Pioneering's good faith estimate as of the date of publication and may be modified in the future.

The mission of Speechify is to make sure that reading is never a barrier to learning.

Over 50 million people use Speechify’s text-to-speech products to turn whatever they’re reading – PDFs, books, Google Docs, news articles, websites – into audio, so they can read faster, read more, and remember more. Speechify’s text-to-speech reading products include its iOS app, Android App, Mac App, Chrome Extension, and Web App. Google recently named Speechify the Chrome Extension of the Year and Apple named Speechify its 2025 Design Award winner for Inclusivity.  

Today, nearly 200 people around the globe work on Speechify in a 100% distributed setting – Speechify has no office. These include frontend and backend engineers, AI research scientists, and others from Amazon, Microsoft, and Google, leading PhD programs like Stanford, high growth startups like Stripe, Vercel, Bolt, and many founders of their own companies.

Overview

The responsibilities of our Platform team include building and maintaining all backend services, including, but not limited to, payments, analytics, subscriptions, new products, text to speech, and external APIs.

This is a key role and ideal for someone who thinks strategically, enjoys fast-paced environments, is passionate about making product decisions, and has experience building great user experiences that delight users.

We are a flat organization that allows anyone to become a leader by showing excellent technical skills and delivering results consistently and fast. Work ethic, solid communication skills, and obsession with winning are paramount. 

Our interview process involves several technical interviews and we aim to complete them within 1 week. 

What You’ll Do

• Design, develop, and maintain robust APIs including public TTS API, internal APIs like Payment, Subscription, Auth and Consumption Tracking, ensuring they meet business and scalability requirements
• Oversee the full backend API landscape, enhancing and optimizing for performance and maintainability
• Collaborate on B2B solutions, focusing on customization and integration needs for enterprise clients
• Work closely with cross-functional teams to align backend architecture with overall product strategy and user experience

An Ideal Candidate Should Have

• Proven experience in backend development: TS/Node (required)
• Direct experience with GCP and knowledge of AWS, Azure, or other cloud providers
• Efficiency in ideation and implementation, prioritizing tasks based on urgency and impact
• Preferred: Experience with Docker and containerized deployments
• Preferred: Proficiency in deploying high availability applications on Kubernetes

What We Offer

• A dynamic environment where your contributions shape the company and its products
• A team that values innovation, intuition, and drive
• Autonomy, fostering focus and creativity
• The opportunity to have a significant impact in a revolutionary industry
• Competitive compensation, a welcoming atmosphere, and a commitment to an exceptional asynchronous work culture
• The privilege of working on a product that changes lives, particularly for those with learning differences like dyslexia, ADD, and more
• An active role at the intersection of artificial intelligence and audio – a rapidly evolving tech domain

The United States Based Salary range for this role is: 140,000-200,000 USD/Year + Bonus + Stock depending on experience

Think you’re a good fit for this job? 

Tell us more about yourself and why you're interested in the role when you apply.
And don’t forget to include links to your portfolio and LinkedIn.

Not looking but know someone who would make a great fit? 

Refer them! 

Speechify is committed to a diverse and inclusive workplace. 

Speechify does not discriminate on the basis of race, national origin, gender, gender identity, sexual orientation, protected veteran status, disability, age, or other legally protected status.

Flagship Pioneering is a scientific innovation engine that invents and builds companies that change the world. We bring together the greatest scientific minds with entrepreneurial company builders and assemble the capital to allow them to take courageous leaps in human health, sustainability, and beyond. 

What sets Flagship apart is our ability to advance biotechnology by uniting life science innovation, company creation, and capital investment under one roof in a way that is largely without precedent. Our team of scientists, entrepreneurial leaders, and professional capital managers are each aligned around an institutionalized process that enables us to innovate and create breakthroughs for the benefit of people and planet.
Many of the companies Flagship has founded have addressed humanity’s most urgent challenges: vaccinating billions of people against COVID-19, curing intractable diseases, improving human health, preempting illness, and feeding the world by improving the resiliency and sustainability of agriculture.

Flagship has been recognized twice on FORTUNE’s “Change the World” list, an annual ranking of companies that have made a positive social and environmental impact through activities that are part of their core business strategies, and has been named four times to Fast Company’s annual list of the World’s Most Innovative Companies.

Role Overview

This is a high‑impact role at the intersection of science, strategy, and business, focused on shaping and advancing a differentiated BioMedicines R&D portfolio from early discovery through clinical development and commercialization readiness.

The role partners closely with senior BioMedicines and Flagship Pioneering leadership to define portfolio direction, build new R&D programs, and drive high‑stakes investment and prioritization decisions. You will work hands‑on with scientific leaders, internal venture teams, and partnering colleagues to translate complex science into clear strategies, executable plans, and compelling executive narratives.

Success in this role requires a roll‑up‑your‑sleeves mindset—owning analyses, building materials, structuring decisions, and moving work forward in a fast‑paced, ambiguity‑rich environment.

What You’ll Do

• Shape portfolio strategy and investment decisions across the BioMedicines pipeline, from preclinical inception through development
• Build and advance new R&D programs, defining development paths, milestones, resourcing plans, and decision points
• Develop integrated investment cases that synthesize scientific rationale, development feasibility, execution risk, and value creation
• Lead portfolio reviews, scenario planning, and trade‑off analyses (e.g., indication selection, timing, resourcing, probability‑adjusted value)
• Evaluate internal and external opportunities, including scientific, technical, strategic, and operational diligence of prospective assets
• Identify portfolio risks, gaps, and opportunities and recommend actions such as acceleration, de‑prioritization, partnering, or termination
• Translate complex scientific, clinical, and financial information into concise, executive‑level insights and decision materials
• Collaborate across R&D, Clinical Development, Regulatory, CMC, Finance, Commercial, Partnering, and internal venture teams
• Work directly with senior scientific and executive leaders (e.g., CSOs, CMOs, CBOs) to create and execute new programs
• Support governance and decision‑making forums that enable speed, clarity, and accountability
• Contribute to special strategic initiatives with the Head of Global Initiatives and SVP, Global Initiatives

Who You Are

You are a scientifically trained strategist who thrives at the boundary of deep science and structured problem‑solving. You are comfortable operating with senior leaders and equally comfortable doing the work yourself—from framing questions to building analyses and influencing decisions.

Qualifications

• PhD or MD in Life Sciences or a related field
• 5+ years of experience in management consulting (strategy and/or life sciences), biotech venture creation or investing, biopharma portfolio strategy, or related roles
• Strong understanding of biopharma R&D, clinical development, and regulatory pathways
• Experience working across multiple programs and stages of drug development
• Demonstrated experience with portfolio construction, scenario planning, and risk‑adjusted decision‑making
• Exceptional ability to synthesize complex data and communicate clearly with executives
• Proven ability to influence senior scientific and business leaders without formal authority
• Experience within the Flagship ecosystem is strongly valued

Equal Opportunity Employer

Flagship Pioneering is an Equal Opportunity Employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, national origin, disability, or protected veteran status. 

#LI-NM1

The salary range for this role is $172,000 - $236,500. Compensation for the role will depend on a number of factors, including a candidate’s qualifications, skills, competencies, and experience. Flagship Pioneering currently offers healthcare coverage, annual incentive program, retirement benefits and a broad range of other benefits. Compensation and benefits information is based on Flagship Pioneering's good faith estimate as of the date of publication and may be modified in the future.

THE ROLE 

As an Associate or Senior Associate at Flagship Pioneering in Molly Gibson’s Pioneering Business Unit (PBU), you will ideate, research, and refine novel venture hypotheses, validate key underlying unknowns of biology or technology and transition pressure-tested ideas into building a NewCo around the science.  You will help drive every facet of company origination from the early stages including identification and recruitment of critical partners and advisors, establishment of foundational IP, hiring and leadership of the early scientific team, and establishment of working norms and culture for the team.  In this role you will partner with stakeholders across the broader Flagship ecosystem to bring the full experience of Flagship to support your companies.  A successful candidate will become the expert on the foundational science of the company, frame and clearly communicate the strategy, and translate that strategy into a plan and lead operationalization of that plan alongside a Principal or Partner on the venture creation team. 

THE COMPANY 

Flagship Pioneering is a scientific innovation engine that invents and builds companies that change the world. We bring together the greatest scientific minds with entrepreneurial company builders and assemble the capital to allow them to take courageous leaps in human health, sustainability, and beyond. 

What sets Flagship apart is our ability to advance biotechnology by uniting life science innovation, company creation, and capital investment under one roof in a way that is largely without precedent. Our team of scientists, entrepreneurial leaders, and professional capital managers are each aligned around an institutionalized process that enables us to innovate and create breakthroughs for the benefit of people and planet.
Many of the companies Flagship has founded have addressed humanity’s most urgent challenges: vaccinating billions of people against COVID-19, curing intractable diseases, improving human health, preempting illness, and feeding the world by improving the resiliency and sustainability of agriculture.

Flagship has been recognized twice on FORTUNE’s “Change the World” list, an annual ranking of companies that have made a positive social and environmental impact through activities that are part of their core business strategies, and has been named four times to Fast Company’s annual list of the World’s Most Innovative Companies.

KEY RESPONSIBILITIES 

• Contribute to and lead Flagship model explorations to rapidly assess interesting areas of science and develop novel, actionable and high value venture hypotheses 

• Outline key scientific questions to enable venture hypotheses and develop experimental plans to rapidly create value and pressure test ideas 

• Identify, build, and maintain relationships with appropriate academic KOLs and thought experts, ie, introducing them to the Flagship model, getting early buy-in, vetting/validation and de-risking key concepts of venture hypotheses 

• Understand IP landscape, formulate initial strategy, and write seminal applications for the technology and company. Assess patentability of existing IP landscape, including of key competitors and of potentially licensable estate 

• Develop corporate strategy and operations plan for the company. Define value creation, identify application spaces, build out organizational chart, define company goals, timelines and resourcing and identify strategic inflection points to set the company on the path to rapid growth and success 

• Develop audience-specific pitches for company 

• Support business development activities and continue to evolve the story 

• Manage and coordinate early scientific and IP employees. Source, recruit and manage KOLs and early-stage employees as well as relationships with CROs. 

• Manage & lead scientific team (internal or external) and daily research. Manage operational tasks, including establishing lab facilities, purchasing, HR, real estate acquisition, etc. 

• Become institutional subject matter expert and transfer to active company team. Stay up to date on the literature, conferences, funding opportunities, and new developments. 

• Work closely with and leverage Flagship operations teams (Finance, IP, IT, HR, and Talent) expertise for maximal operational excellence 

PROFESSIONAL EXPERIENCE & QUALIFICATIONS  

The ideal candidate has a STEM-based PhD or MD from a top university and 2 or more years of experience in life sciences biotech, start-up or entrepreneurial activities. The candidate must have a passion for novel science and be operationally savvy. 

 Important skills and capabilities include: 

• Proven ability to rapidly become conversant in new areas of science and capable of engaging thought leaders at the deepest level of technological understanding 

• Ability to define a clear and compelling value proposition of a given scientific opportunity and effectively and cogently communicate that to technical and non-technical audiences 

• Basic understanding of multiple therapeutic modalities of drug discovery including small molecule, ADC, and protein therapeutics 

• Excellent analytical skills and ability to synthesize & communicate complex information rapidly and effectively 

• Energetic self-starter with strong presence and the ability to work effectively in an entrepreneurial environment 

• Open, transparent communication style and demonstrated willingness to engage in difficult conversations in a professional and productive manner 

• Passion for growth and development, with clear demonstration of openness to both giving and receiving feedback and track record of acting on feedback 

• Able to work effectively and pleasantly in teams with demonstrated abilities to lead and manage 

• Unmatched sense of urgency 

Flagship Pioneering and our ecosystem companies are committed to equal employment opportunity regardless of race, color, ancestry, religion, sex, national origin, sexual orientation, age, citizenship, marital status, disability, gender identity or Veteran status. 

At Flagship, we recognize there is no perfect candidate. If you have some of the experience listed above but not all, please apply anyway. Experience comes in many forms, skills are transferable, and passion goes a long way. We are dedicated to building diverse and inclusive teams and look forward to learning more about your unique background.

Recruitment & Staffing Agencies: Flagship Pioneering and its affiliated Flagship Lab companies (collectively, “FSP”) do not accept unsolicited resumes from any source other than candidates. The submission of unsolicited resumes by recruitment or staffing agencies to FSP or its employees is strictly prohibited unless contacted directly by Flagship Pioneering’s internal Talent Acquisition team. Any resume submitted by an agency in the absence of a signed agreement will automatically become the property of FSP, and FSP will not owe any referral or other fees with respect thereto.

 More About Flagship Pioneering:

We are creative optimists, and we would love for you to consider joining our team!  See all our open opportunities across Flagship Pioneering’s Ecosystem!

Flagship Pioneering conceives, creates, resources, and develops first-in-category life sciences companies to transform human health and sustainability. Since its launch in 2000, the firm has applied a unique hypothesis-driven innovation process to originate and foster more than 100 scientific ventures, resulting in over $34 billion in aggregate value. To date, Flagship is backed by more than $4.4 billion of aggregate capital commitments, of which over $1.9 billion has been deployed toward the founding and growth of its pioneering companies alongside more than $10 billion of follow-on investments from other institutions. The current Flagship ecosystem comprises 41 transformative companies, including:  Axcella Health (NASDAQ: AXLA), Denali Therapeutics (NASDAQ: DNLI), Evelo Biosciences (NASDAQ: EVLO),  Foghorn Therapeutics, Indigo Ag, Kaleido Biosciences (NASDAQ: KLDO), Moderna (NASDAQ: MRNA), Rubius Therapeutics (NASDAQ: RUBY), Sana Biotechnology, Seres Therapeutics (NASDAQ: MCRB), and Syros Pharmaceuticals (NASDAQ: SYRS).

#LI-TD1

The salary range for this role is $155,000 - $190,000. Compensation for the role will depend on a number of factors, including a candidate’s qualifications, skills, competencies, and experience. Flagship Pioneering currently offers healthcare coverage, annual incentive program, retirement benefits and a broad range of other benefits. Compensation and benefits information is based on Flagship Pioneering's good faith estimate as of the date of publication and may be modified in the future.

About Pioneering Intelligence

Pioneering Intelligence builds on Flagship Pioneering's legacy of founding cutting-edge science and computational ventures, harnessing recent advances in AI, machine learning, and data to accelerate fundamental research and create a portfolio of AI-first companies. As part of Flagship's integrated model of science, entrepreneurship, and capital, it transforms breakthrough ideas into world-changing companies, elevating the AI advances happening across the ecosystem in human health, sustainability, and beyond.

The Role

The Pioneering Intelligence team at Flagship Pioneering builds the digital and AI foundation that accelerates the creation and growth of our companies. We are seeking a Vice President of Engineering to lead a medium sized team of Principal Software Engineers, each operating as the technical authority for their own product area.

This is a non-traditional engineering leadership role. Rather than managing a layered organization, you will build and support a team composed entirely of senior individual contributors operating as technical leads at the highest level. Each engineer owns end-to-end technical decisions, builds hands-on, and engages directly with scientific users. Your job is not to manage their work but to set the conditions in which exceptional engineers do their best work, remove obstacles, raise the collective bar, and translate technical strategy into organizational direction.

You remain technically active. You will contribute to architectural decisions, review complex system designs, and stay close enough to the work to lead credibly. You spend roughly 25% of your time in hands-on technical work. The rest is spent on strategy, people, and organizational leadership: building the team, aligning with product leadership, representing the function to senior stakeholders, and driving the conditions for fast, high-quality delivery across the portfolio.

The model is intentionally fluid. Principal Engineers on this team may move between pure IC work and the formal coordination of other resources as project needs evolve, including the management of fully embedded software engineering contractors. It is the VP who balances resources across all teams and projects, in close collaboration with product and strategy leads, ensuring the right people are working on the right things at the right time.

You will work in close partnership with product and strategy leads and alongside a team of peers who expect the same rigor and accountability from you that you expect from them.

Key Responsibilities

• Lead and develop a team of approximately five Principal Software Engineers, each owning technical authority for their own product area
• Set technical strategy and architectural direction for the AI and digital platform, making or ratifying the most consequential build-vs-buy and system design decisions
• Stay technically active: contribute to architectural reviews, design complex systems, and maintain the credibility to lead a team of principal-level engineers
• Build and maintain the team itself: hire exceptional engineers, develop their careers, and create a culture where the floor is principal-level performance
• Represent engineering to product leadership, senior stakeholders, and across the Flagship ecosystem, translating technical direction into business impact
• Balance resources across all teams and projects in close collaboration with product and strategy leads, including decisions about when Principal Engineers take on formal coordination of embedded SWE contractors versus pure IC work
• Drive delivery across the portfolio by removing blockers, resolving cross-team dependencies, and ensuring the team ships with speed and quality
• Model and advance an AI-native engineering culture, including the use of tools like Claude Code as organizational force multipliers

Professional Experience and Qualifications

Experiences

• Has led a team of senior individual contributors or principal-level engineers, ideally in a lean, high-velocity organization where the team was small and the scope was large
• Has served as the technical authority on a complex, production-grade system, not as a manager who delegates the hard parts, but as an engineer who owned them
• Has built and scaled engineering organizations in ambiguous, fast-moving environments, ideally at a startup or within a high-autonomy team inside a larger organization
• Has worked closely with scientific or domain-expert users and understands how to build products that serve researchers, not just operators
• Has hired and developed principal or staff-level engineers, with a track record of raising the technical bar of a team over time

Skills

• Technically credible at the system design level: can evaluate architectural decisions, identify risk in complex designs, and contribute meaningfully to the hardest engineering conversations
• Leads through clarity: sets direction, makes decisions, and communicates tradeoffs without requiring repeated alignment
• Builds teams, not just products: knows how to hire exceptionally, develop senior talent, and create conditions where strong engineers stay and grow
• Fluent in AI-native ways of working and comfortable leading a team that uses tools like Claude Code as a core part of their engineering practice
• Writes with the same precision they expect from their engineers: strategy docs, architectural reviews, and hiring rubrics that don't require a follow-up meeting

Traits

• Strategic and hands-on at the same time: comfortable moving between organizational leadership and technical depth without losing credibility in either
• High standards without bureaucracy: holds the team to an exceptional bar without slowing them down with process for its own sake
• Founder-minded: attracted to ambiguity, motivated by impact, and able to build clarity from uncertainty rather than waiting for it to arrive
• Direct and decisive: makes calls with available information, owns the outcomes, and creates psychological safety for their team to do the same
• Multiplier, not bottleneck: earns trust by making the people around them better, not by centralizing decisions

Why Pioneering Intelligence?

• Lead a team of principal-level engineers where the work is genuinely hard and the people are genuinely exceptional
• Shape the technical strategy of an AI-native platform at the intersection of cutting-edge AI and life sciences
• Operate with the autonomy and organizational support to build the team and culture you believe in
• Work at the frontier of AI-augmented engineering, where the tools are state-of-the-art and the model of how software gets built is being reinvented
• Collaborate with visionary scientists, founders, and builders across Flagship's ecosystem
• Competitive compensation and benefits, including equity, commensurate with experience

About Flagship Pioneering

Flagship Pioneering invents and builds platform companies, each with the potential for multiple products that transform human health, sustainability and beyond. Since its launch in 2000, Flagship has originated more than 100 companies. Many of these companies have addressed humanity’s most urgent challenges: vaccinating billions of people against COVID-19, curing intractable diseases, improving human health, preempting illness, and feeding the world by improving the resiliency and sustainability of agriculture.  

Flagship has been recognized twice on FORTUNE’s “Change the World” list, an annual ranking of companies that have made a positive social and environmental impact through activities that are part of their core business strategies and has been twice named to Fast Company’s annual list of the World’s Most Innovative Companies. Learn more about Flagship at www.flagshippioneering.com.

At Flagship, we accept impossible missions to enable bigger leaps. Our core values guide us through uncertainty and toward lasting impact.

We are an equal opportunity employer. All qualified applicants will be considered for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, disability, protected veteran status, or any other characteristic protected by law.

We recognize that great candidates often bring unique strengths without fulfilling every qualification. If you have some of the experience listed above but not all, please apply anyway. We are dedicated to building diverse and inclusive teams and look forward to learning more about your background and interest in Flagship.

Recruitment & Staffing Agencies: Flagship Pioneering and its affiliated Flagship Lab companies (collectively, “FSP”) do not accept unsolicited resumes from any source other than candidates. The submission of unsolicited resumes by recruitment or staffing agencies to FSP or its employees is strictly prohibited unless contacted directly by Flagship Pioneering’s internal Talent Acquisition team. Any resume submitted by an agency in the absence of a signed agreement will automatically become the property of FSP, and FSP will not owe any referral or other fees with respect thereto.

The salary range for this role is $313,000 - $400,000. Compensation for the role will depend on a number of factors, including a candidate’s qualifications, skills, competencies, and experience. Pioneering Intelligence currently offers healthcare coverage, annual incentive program, retirement benefits and a broad range of other benefits. Compensation and benefits information is based on Pioneering Intelligence's good faith estimate as of the date of publication and may be modified in the future.

The Opportunity:

As part of the Pharmaceutical Development team, this position will play a key role in regulatory strategy development and execution of assigned Chemistry, Manufacturing and Control (CMC) programs.

Your Role: 

• You will serve as CMC-regulatory lead for assigned projects.
• Develop and execute CMC global submission plans and timelines in accordance with project goals
• You will lead the preparation/plans, review, and on-time submission of CMC sections for IND/IMPD/CTA, NDA/MAA and other global regulatory filings including IB, DSUR, annual updates, briefing books etc. in conjunction with regulatory affairs and CMC/Pharmaceutical Development leads/SMEs.
• You will be responsible for coordination of responses to CMC questions/RFIs from regulatory authorities in conjunction with CMC and regulatory affairs leads/SMEs.
• You will lead CMC-regulatory activities listed above with cross-functional teams and act as the regulatory CMC liaison between CMC/PD, regulatory affairs and/or program management, as applicable.
• You will lead and manage CMC-regulatory assessment and guidance on product compliance topics, including change controls, deviations, and GMP investigations, in conjunction and consultation with CMC leadership.
• You will keep abreast of regulatory guidance and technical/scientific developments relevant to projects.

Competencies:

• Strong background in Regulatory Affairs-CMC with a focus on small molecule clinical (IND/IMPD) and/or commercial (NDA/MAA) submissions.
• Proven ability to lead and manage regulatory CMC projects with minimal supervision
• In-depth knowledge of global CMC regulatory requirements and guidelines (e.g. FDA, EMA, ICH).
• Positive attitude, energetic and proactive.
• Strong technical writing and document review skills.
• Excellent organizational skills, ability to multi-task and prioritize assignments, operational creativity, strong problem-solving skills, self-motivated and able to work under pressure.
• Strategic thinking capabilities with forward looking perspective and ability to find solutions, in alignment with management and program goals, strong communication, planning, and collaboration skills
• Attention to detail, follow-up/through skills; ability to work individually and within multi-disciplinary internal and external teams at third parties.
• Ability to effectively manage multiple projects with competing priorities.

Your Qualifications:

• Bachelor or advanced degree in Pharmaceutical Sciences, Chemistry or related fields.
• Minimum of 8+ years of relevant experience in regulatory-CMC and/or within CMC function (e.g. analytical, formulation and process development, QA, QC) in the biotech/pharmaceutical industry with a focus preferably on CMC for small molecules and oral solid products.
• Experience with authoring/review/providing CMC content for CMC/quality submissions including IND and IMPD development/maintenance.
• Knowledge of eCTD Module 3 and QOS requirements for INDs/IMPDs and NDAs/MAAs.
• Experience managing submissions in RIM Veeva or equivalent; document formatting/Quality Control compliant with eCTD templates / requirements.
• Authoring experience of CTD Module 2 & Module 3 sections.

Estimated Salary Range: [$145,000 - $207,000].

The range provided above is based on what we believe to be a reasonable estimate for this job at the time of posting. Actual base salary will depend on a number of factors, including but not limited to, a candidate’s education, experience, skills and location.

#BP1

What if... We could harness the power of Flagship’s scientific platforms and create novel treatment options that benefit more patients, sooner?

Pioneering Medicines is dedicated to conceiving and developing a broad portfolio of life-changing treatments by leveraging and expanding the use of Flagship’s multiple bioplatforms and Flagship’s proprietary innovation process. By harnessing the power of Flagship’s first-in-category platforms, Pioneering Medicines creates and advances novel medicines, partnering with Flagship companies to accelerate the extension of their portfolios into new areas and show that the platform can be applied more broadly, thereby delivering benefits to more patients, sooner. With a highly experienced drug development team and access to the wide ecosystem of Flagship companies, Pioneering Medicines is well positioned to conceive new medicine ideas both internally and in collaboration with strategic partners and advance these assets through to significant value inflection. 

Position Summary

As the Director, Business Development, Transactions you will be responsible for leading strategic transactions for Pioneering Medicines and for select company's across the Flagship ecosystem.  This role requires the ability to influence up, down and across the ecosystem as well as strong organizational, communication and presentation skills. The successful candidate will have scientific acumen, the ability to think and act strategically, be deeply collaborative, and will thrive in a fast-paced, entrepreneurial environment.

Key Responsibilities

In this role you will lead the structuring, negotiating and completion of in-licensing, out-licensing and asset sale transactions for Pioneering Medicines and for negotiating all types of strategic transactions for companies across the Flagship ecosystem.  Additional responsibilities include leading diligence and financial analysis in support of new deals and presenting key findings to company leadership and investment decision-makers. 

Specific Responsibilities

• Collaborate closely with other members of the Partnering team and cross-functional leaders to shape and execute Flagship's business development strategy.
• Establish credibility across the organization through a deep understanding of the biotech and pharmaceutical deals landscape.
• Prepare opportunity assessments with scientific/portfolio rationale, partnership framework and financial assessment, analysis of competitive landscape and comparable deal terms
• Foster strong cross-functional collaboration with R&D, operations, finance, and legal.
• Drive engagement with potential top tier pharmaceutical partners establishing relationships and communicating the vision of the Flagship ecosystem.
• Identify, implement, and continuously refine best practices for partnership operations, program tracking, and execution.
• Lead the coordination and execution of key internal Partnering meetings, ensuring effective agenda setting, action tracking, and follow-up.
• Develop guiding principles and objectives, then track execution against these objectives; develop joint ways of working, and participate in health checks for key partners.

Key Qualifications

• Bachelor’s degree in life sciences, business administration, or a related field; MBA or relevant advanced degree a plus.
• Expertise with contracts and a track record of negotiations.
• 5+ years of experience in business development, partnership management or alliance management within a large pharma or biotech environment.
• Strong analytical, financial, problem-solving, and decision-making skills with the ability to manage multiple priorities.
• Ability to interface with external partners.
• Demonstrated experience managing complex relationships and driving operational efficiencies.
• Proven ability to collaborate across diverse functions and lead cross-functional initiatives.
• Excellent communication and organizational skills with strong executive presence.
• Strong leadership skills and proven ability to influence others to reach common goals as well as act independently.
• Ability to thrive in a fast-paced, evolving environment and drive continuous improvement.
• Self-motivated, attention to detail, and proven ability to work well in teams.

What We’ll Offer You

• Comprehensive, competitive healthcare and dental coverage through Blue Cross Blue Shield, vision coverage through VSP, family leave, paid flexible time off, 401k retirement plan, disability and life insurance, mental health program via Calm, backup care for children/senior and fully covered parking/commuter benefits.
• A dynamic work environment with entrepreneurial spirit and highly interdisciplinary, talented, and collaborative team. Opportunities to work with Flagship scientific platforms/portfolios and create novel treatment options that benefit more patients sooner.
• Professional growth opportunities through mentoring, training, immersion in cross-functional projects, and opportunities to learn and try new things.

About Flagship 

Flagship Pioneering is a scientific innovation engine that invents and builds companies that change the world. We bring together the greatest scientific minds with entrepreneurial company builders and assemble the capital to allow them to take courageous leaps in human health, sustainability, and beyond. 
 
What sets Flagship apart is our ability to advance biotechnology by uniting life science innovation, company creation, and capital investment under one roof in a way that is largely without precedent. Our team of scientists, entrepreneurial leaders, and professional capital managers are each aligned around an institutionalized process that enables us to innovate and create breakthroughs for the benefit of people and planet. 
 
 Many of the companies Flagship has founded have addressed humanity’s most urgent challenges: vaccinating billions of people against COVID-19, curing intractable diseases, improving human health, preempting illness, and feeding the world by improving the resiliency and sustainability of agriculture.  Flagship has been recognized twice on FORTUNE’s “Change the World” list, an annual ranking of companies that have made a positive social and environmental impact through activities that are part of their core business strategies, and has been named four times to Fast Company’s annual list of the World’s Most Innovative Companies. 

At Flagship, we recognize there is no perfect candidate. If you have some of the experience listed above but not all, please apply anyway. Experience comes in many forms, skills are transferable, and passion goes a long way. We are dedicated to building diverse and inclusive teams and look forward to learning more about your unique background. 

Recruitment & Staffing Agencies: Flagship Pioneering and its affiliated Flagship Lab companies (collectively, “FSP”) do not accept unsolicited resumes from any source other than candidates. The submission of unsolicited resumes by recruitment or staffing agencies to FSP or its employees is strictly prohibited unless contacted directly by Flagship Pioneering’s internal Talent Acquisition team. Any resume submitted by an agency in the absence of a signed agreement will automatically become the property of FSP, and FSP will not owe any referral or other fees with respect thereto.

#LI-TD1

The salary range for this role is $172,000 - $236,500. Compensation for the role will depend on a number of factors, including a candidate’s qualifications, skills, competencies, and experience. Pioneering Medicines currently offers healthcare coverage, annual incentive program, retirement benefits and a broad range of other benefits. Compensation and benefits information is based on Pioneering Medicines's good faith estimate as of the date of publication and may be modified in the future.

Company Description 

FL121 is a privately held biotechnology company engineering nature to build next generation therapeutics. By harnessing naturally occurring chemistry and pairing it with sophisticated high-throughput screening technology, we will unlock the future of de novo drug design via curated data creation and model training.  

Role Overview 

We are building a therapeutic discovery platform centered on biosynthetically-derived chemistry and advanced analytical readouts. This role will provide direct experimental support to the platform’s Build arm: executing cloning, expression, and purification workflows with a high degree of independence and rigor. The Sr. RA will be a hands-on contributor to day-to-day bench operations and will help maintain the throughput and data quality needed to drive rapid, data-grounded decisions. 

Key Responsibilities 

• Execute molecular cloning workflows end-to-end using modern assembly methods (Gibson, T2S/Golden Gate, and related approaches); maintain accurate plasmid maps, sequence records, and construct libraries. 

• Express and purify recombinant proteins in bacterial systems; independently troubleshoot yield, solubility, and purity issues across the full workflow from culture through final polishing steps. 

• Maintain rigorous records of experimental conditions, reagent lots, and QC data; contribute to reproducible, well-documented protocols and sample tracking practices that support downstream analytical and screening steps. 

• Partner with senior scientists and cross-functional teams to deliver high-quality material inputs that enable platform proof-of-concept experiments; communicate results and blockers clearly and proactively. 

Required Skills and Experience 

• Demonstrated proficiency in modern DNA assembly methods (Gibson Assembly, Type IIS/Golden Gate, and related scarless cloning strategies); able to take a construct from design to sequence-verified clone independently. 

• Hands-on experience with recombinant protein expression (E. coli required; additional systems a plus) and purification by affinity chromatography and related downstream steps; able to assess purity and integrity via analytical methods. 

• Familiarity with standard analytical tools (chromatography, gel electrophoresis, UV absorbance) and biochemical assays (ELISA, BLI) for protein and DNA characterization 

• Track record of executing multi-step molecular biology workflows end-to-end with minimal supervision; strong attention to detail in protocol execution and data recording. 

• Senior Research Associate: Typically requires a BS degree in a relevant scientific discipline with 5+ years of industry experience; or a Master’s degree in a relevant scientific discipline with 3+ years of experience. Academic experience including co-ops and internships counts toward degree requirements and not work experience. 

Preferred Experience 

• Experience supporting or interfacing with mass spectrometry-based readouts. 

• Experience with laboratory automation platforms, LIMS/sample tracking systems, or basic scripting (Python/R) for data organization and analysis. 

What it Takes to Succeed in This Role 

• Comfort in ambiguity; can move between strategy and execution. 

• Creative and rigorous in experimental design, documentation, and data interpretation. 

• Collaborative communicator; gives/receives feedback effectively. 
• Grit and agility in fast-moving environments. 

Values and Behaviors 

We are seeking individuals with an entrepreneurial spirit, strong communication skills, and comfort working in and contributing to a dynamic and cross-functional team environment. The level of the role will be commensurate with the education and years of experience of the identified candidate. 

At Flagship, we recognize there is no perfect candidate. If you have some of the experience listed above but not all, please apply anyway. Experience comes in many forms, skills are transferable, and passion goes a long way. We are dedicated to building diverse and inclusive teams and look forward to learning more about your unique background. 

Recruitment & Staffing Agencies: Flagship Pioneering and its affiliated Flagship Lab companies (collectively, “FSP”) do not accept unsolicited resumes from any source other than candidates. The submission of unsolicited resumes by recruitment or staffing agencies to FSP or its employees is strictly prohibited unless contacted directly by Flagship Pioneering’s internal Talent Acquisition team. Any resume submitted by an agency in the absence of a signed agreement will automatically become the property of FSP, and FSP will not owe any referral or other fees with respect thereto. 

The salary range for this role is $81,000 - $107,250. Compensation for the role will depend on a number of factors, including a candidate’s qualifications, skills, competencies, and experience. FL121 currently offers healthcare coverage, annual incentive program, retirement benefits and a broad range of other benefits. Compensation and benefits information is based on FL121's good faith estimate as of the date of publication and may be modified in the future.

Director, People and Culture Business Partner

Location: Cambridge and Watertown, MA (between two sites at least 3 days a week)

Reports To: VP, Senior People and Culture Business Partner

Who We Are

At Prime Medicine, we're not just editing genes — we're rewriting what's possible for patients living with debilitating genetic diseases. Built on the groundbreaking Prime Editing platform, a next-generation "search and replace" technology, we are on a mission to deliver potentially curative therapies to patients who have waited long enough.

Our team of scientists, engineers, and operators is intensely curious, deeply collaborative, and united by a shared belief: that the right science, paired with the right people, can change the course of disease. We move fast, think boldly, and take our work seriously — while making sure we enjoy the journey together.

This is a pivotal moment for Prime Medicine. We are focused, energized, and building toward breakthroughs that matter. If you want to do the most meaningful work of your career alongside people who feel the same, you've found your place.

The Opportunity

Prime Medicine is seeking a Director, People and Culture Business Partner — a passionate, people-first HR professional who is as comfortable shaping culture as they are rolling up their sleeves on the operational fundamentals that keep a growing biotech humming.

Reporting to the VP, Senior People and Culture Business Partner, you'll be a trusted partner to Prime's management and employees alike - someone who connects deeply with the business, champions our culture, and helps ensure our people strategy keeps pace with our science. At Prime, People & Culture is a strategic driver of our mission.

This role is for someone who works hard, has fun, and genuinely believes that great organizations are built one person, one team, and one conversation at a time.

What You'll Do

Be a Culture Champion

• Show up as the heart of our employee experience — approachable, credible, and genuinely invested in the people you work with.
• Partner with managers and employees to reinforce and evolve Prime's culture and values as the company grows.
• Support employee engagement initiatives and translate listening efforts (surveys, conversations, data) into meaningful action.
• Help to continue to make Prime the kind of place where brilliant people do their best, most fulfilling work.

Drive Talent Strategy

• Identify development opportunities that deepen our talent bench and build organizational capability for the long term.
• Support creative career pathing efforts and employee development programs that reflect Prime's startup spirit and scientific ambition.
• Serve as a true Talent Ambassador — someone employees, management, external vendors and candidates are excited to engage with.

Partner Strategically with the Business

• Partner closely with management to drive organizational effectiveness, workforce planning, and thoughtful change management.
• Translate Prime's evolving business priorities and values into people strategies that create real impact.
• Lead organizational design efforts and guide teams through change with clarity and care.
• Provide counsel that's both candid and compassionate on employee relations and management challenges.

Execute with Excellence

• Ensure flawless execution of core HR cycles: administration, compensation planning, promotions, talent mobility, headcount planning, recruitment, and workforce planning.
• Partner with Total Rewards to navigate compensation cycles effectively and equitably.
• Contribute to policy development and evolving compliance needs as Prime scales — with a pragmatic, startup-savvy lens.

What You Bring

• An advanced degree in Human Resources, Business, Life Sciences, or a related field.
• 10–12+ years of progressive HR experience, with significant HRBP experience supporting managers and employees.
• Deep experience in biotechnology, pharmaceuticals, or life sciences — you understand the cadence, culture, and complexity of science-driven organizations.
• A startup mentality with an operator's mindset: you know when to build from scratch, when to borrow a best practice, and when to just get it done.
• Demonstrated success juggling multiple priorities in a fast-moving environment without losing sight of the details or the people.
• Strong business acumen and executive presence — you influence at all levels, and people trust your judgment.
• A high tolerance for ambiguity, a bias toward action, and a track record of driving measurable outcomes.
• You work hard, have fun, and make the team around you better.

Why Prime Medicine

• Mission that matters: Every program we advance has the potential to change — or save — a life. You'll feel that every day.
• A team you'll love: brilliant, humble, fun people who take the science seriously
• A pivotal moment: Prime is a focused, forward-moving company with a clear path and bold ambitions. You'll help shape what comes next.
• Cambridge at its best: Sit at the epicenter of the world's most dynamic biotech ecosystem.
• A seat at the table: People and Culture is a strategic partner here. Your voice will be heard and your impact will be real.

Prime Medicine is an equal opportunity employer. We celebrate diversity and are committed to creating an inclusive environment where all employees can thrive.

What if… you could join an organization that creates, resources, and builds life sciences companies that invent breakthrough technologies to transform human health and sustainability?

Flagship Pioneering's venture creation engine has conceived and created companies such as Moderna Therapeutics (NASDAQ: MRNA), Rubius Therapeutics (NASDAQ: RUBY), Sana Biotechnology (NASDAQ: SANA), Generate Biomedicines, and Tessera Therapeutics. Since its launch in 2000, Flagship has applied its unique hypothesis-driven innovation process to originate and foster more than 100 scientific ventures, resulting in over $212 billion in aggregate value. To date, Flagship has deployed over $2.5 billion in capital toward the founding and growth of its pioneering companies alongside more than $19 billion of follow-on investments from other institutions. In 2021, Flagship Pioneering was ranked 12thglobally on Fortune’s “Change the World” list, an annual ranking of companies that have made a positive social and environmental impact through activities that are part of their core business strategies.

The Company:

FL116, backed by Flagship Pioneering, is an early-stage biotechnology company transforming the way biomolecules are synthesized. Our innovative platform has the potential to redefine how critical research, diagnostic, and therapeutic molecules are designed and built. We are seeking passionate problem solvers ready to make a profound impact on biotechnology and therapeutic innovation. 

Position Summary:

The Senior Manager of Corporate Development and Enablement will serve as a key strategic and operational partner to the President, driving high-priority initiatives across corporate development, partnerships, investor/board communications, operations, and market-informed product strategy. Operating at the center of the organization, this individual will work cross-functionally with scientific and business leaders to translate complex technical and market insights into clear strategies and actionable plans. The ideal candidate thrives in ambiguity, brings a structured, analytical approach to problem-solving, and is equally comfortable shaping strategy and executing against it in a fast-paced, early-stage biotechnology environment.

Responsibilities:

• Reporting to the president, the successful candidate will lead creation of external/internal company presentations/reports, including board material, pitches and other critical documents
• Convene the weekly company leadership team meeting, managing the agenda and key action items that emerge from the discussion
• Coordinate our major external partnership, ensuring our timelines/budget remain on track, aligning stakeholders, and preparing key update materials
• Support establishment of key vendor relationships, shepherding SOWs, MSAs, and other legal agreements through our approval processes, then tracking deliverables
• Ensure our lab operations and lab space are meeting the company needs; Driving real estate and equipment sourcing strategies.
• Conduct market research with relevant customers, building out product strategies
• Support broader strategic decision making, such as corporate/partnership strategies

Qualifications:

• At least 2 years working in a strategy or strategic-consulting role, ideally with R&D experience; PhD in a technical field is beneficial but not required.
• Deep knowledge and understanding of life sciences. Proficient in distilling key insights from across multiple scientific sources and driving towards conclusions.
• Preference for candidates with proven experience in product strategy, market research, or R&D strategy preferred

Who You Are

• Execution focused and motivated: You thrive in getting things done efficiently and continuing to advance the mission of FL116.
• Collaborative Contributor: You excel in cross-functional teams, readily share expertise, and value the input of colleagues.
• Inventive Problem Solver: You proactively identify challenges and rapidly ideate creative solutions.
• Compelling storyteller: You can translate ideas, both yours and others, into high quality and well-structured communications in any medium, including spoken, presentation, or memo formats.

Location: Cambridge, MA 

Flagship Pioneering and our ecosystem companies are committed to equal employment opportunity regardless of race, color, ancestry, religion, sex, national origin, sexual orientation, age, citizenship, marital status, disability, gender identity or Veteran status.

 Recruitment & Staffing Agencies: Flagship Pioneering and its affiliated Flagship Lab companies (collectively, “FSP”) do not accept unsolicited resumes from any source other than candidates. The submission of unsolicited resumes by recruitment or staffing agencies to FSP or its employees is strictly prohibited unless contacted directly by Flagship Pioneering’s internal Talent Acquisition team. Any resume submitted by an agency in the absence of a signed agreement will automatically become the property of FSP, and FSP will not owe any referral or other fees with respect thereto.

The salary range for this role is $139,000 - $176,000. Compensation for the role will depend on a number of factors, including a candidate’s qualifications, skills, competencies, and experience. FL116 currently offers healthcare coverage, annual incentive program, retirement benefits and a broad range of other benefits. Compensation and benefits information is based on FL116's good faith estimate as of the date of publication and may be modified in the future.

Why Join Us?

Parabilis Medicines is a clinical-stage biopharmaceutical company dedicated to creating extraordinary medicines that unlock high-impact protein targets long-considered undruggable. The company has developed a new class of stabilized, cell-penetrant alpha-helical peptides – Helicons™ – capable of modulating intracellular proteins that are inaccessible to traditional drug modalities.

Headquartered in Cambridge, Mass., Parabilis is advancing a focused pipeline of multiple first-in-class therapies across both rare and common cancers. Its lead asset, zolucatetide (FOG-001), is a first-in-class, clinically validated direct inhibitor of the interaction between β-catenin and the T-cell factor (TCF) family of transcription factors, implicated in millions of cancer cases annually, including in colorectal cancer, desmoid tumors, hepatocellular carcinoma and a range of other Wnt/β-catenin-driven tumors. In Phase 1 clinical trials, zolucatetide produced the first-ever clinical evidence that it can directly inhibit this interaction, once previously considered “undruggable” despite its role across multiple cancer types. Parabilis is also advancing investigational degraders of ERG and ARON into clinical development for the treatment of prostate cancer, as well as progressing other preclinical programs. Backed by a recent $305 million Series F financing, Parabilis is entering an exciting phase of growth and execution.

What’s the opportunity?

This is a rare opportunity to shape and protect the intellectual foundation of a company redefining what’s possible in drug discovery. As Director, Intellectual Property, you will architect and lead the global IP strategy for Parabilis’ Helicon™ platform and pipeline—helping unlock the full value of therapies targeting proteins long considered “undruggable.”

Reporting to the General Counsel, you will operate at the intersection of cutting-edge science and business strategy, partnering closely with Research, Development, CMC, and Business Development to translate breakthrough innovation into durable competitive advantage.

In this highly visible role, you will not only build and scale world-class IP for the organization but also serve as a key strategic advisor to senior leadership—guiding critical decisions across pipeline advancement, partnerships, and long-term value creation.

Key Responsibilities:

• Develop and execute global patent strategies aligned with corporate, R&D, and business objectives.
• Design layered IP protection strategies covering composition of matter, methods of treatment, platform technologies, computational methods, and manufacturing.
• Lead drafting and prosecution of U.S. and international patent applications.
• Conduct invention mining sessions and proactively identify patentable subject matter.
• Oversee global prosecution strategy and manage outside counsel.
• Lead freedom-to-operate analyses and patent landscape assessments.
• Support due diligence for partnerships, collaborations, and financing transactions.
• Serve as primary IP advisor to Research, Clinical, Regulatory, CMC, and Business Development teams.
• Manage IP budgets and implement scalable portfolio tracking systems.
• Present IP strategy updates to senior leadership and Board as needed.

What you’ll need to be successful:

• Ph.D. in chemistry, biochemistry, molecular biology, structural biology, peptide chemistry, protein engineering, or related discipline strongly preferred.
• Registered U.S. Patent Agent or admitted U.S. Patent Attorney in good standing.
• 5+ years of patent experience in biotechnology, including in-house or law firm experience supporting innovative therapeutic platforms.
• Strong familiarity with peptide therapeutics, intracellular delivery systems, oncology drug discovery, and computational drug discovery technologies.
• Demonstrated success building patent estates for platform biotech companies.
• Deep understanding of U.S. and global patent law relevant to life sciences.
• Excellent scientific writing, claim drafting, and strategic communication skills.
• Demonstrated ability to utilize AI tools for day-to-day work; baseline proficiency is expected, and advanced or innovative use of AI is a strong plus.
• Ability to work hybrid preferred; remote considered.

Core Values

Parabilis Medicines is a team of passionate pioneers who are trailblazing the future of precision medicine with the aim of making a meaningful difference in the lives of patients. The company is committed to promoting an inspiring and flourishing working environment for all employees across the business, in all departments, and driving innovation for patient benefit.

• Growth-Minded. We’re inventing a new class of medicines—one applicable to therapeutic targets that have been dreamt about, but always considered impossible to drug. Our work requires us to be curious, humble and adaptable.
• In(ter)dependent. We are fiercely independent as a leader in defying the limitations of current therapeutic modalities, and interdependent as a team as we work collaboratively to shift drug discovery paradigms and provide patients with better treatment options.
• Patient-focused. We are deeply focused on patient outcomes, and all energy in the company is focused on science as it translates to patient impact.
• All-In. We’re All-In on solving some of the hardest scientific challenges and delivering one of the most effective new classes of drugs in history.

The base salary range for this position is $220,000-$290,000 per year, depending on experience, qualifications, and internal practices. Parabilis’s total compensation package also includes an annual target bonus, equity, and a comprehensive suite of competitive benefits designed to support our employees’ overall well-being.

As an equal opportunity employer, Parabilis Medicines values an inclusive workplace and welcomes applicants of all backgrounds and experiences. All qualified applicants will receive consideration for employment without discrimination on the basis of race, color, religion, sex, sexual orientation, gender identity, national origin, protected veteran status, disability, or any other factors prohibited by law.

30 Acorn Park Drive    |     Cambridge, MA 02140    |    www.parabilismed.com