Van Leeuwen Ice Cream is hiring seasonal, part-time Scoopers to join our Harvard Sq ice cream shop in Cambridge, MA.

Our Scoopers are the ultimate Van Leeuwen ambassadors, bringing our high standards and hospitality to life in every guest interaction. We’re looking for self-starters who thrive independently and as part of a team in a fast-paced, high-energy environment. The ideal candidate brings positive energy, strong people skills and a genuine passion for ice cream!

This position is SEASONAL and is directly tied to the peak demands of the summer months. The end date of employment is 10/07/2026 unless otherwise specified in the interview.

Seasonal Part Time Scoopers at Van Leeuwen's scoop shops make $17.00 per hour + an average of an additional $4.50-$8 per hour in tips! Tips are based on averages and subject to seasonal fluctuation. Our team members must have availability to work at least three shifts per week and be available to work past 12am.

JOB RESPONSIBILITIES

• Greet every guest warmly, with enthusiasm and genuine hospitality
• Able to scoop and serve guests all menu items while maintaining quality and presentation standards
• Serve as a Van Leeuwen Ambassador, educating guests on flavors, ingredients and special offerings
• Prepare all fresh, house made menu items daily
• Accurately operate our Square POS System for a seamless guest checkout process
• Ability to become familiar with all food safety procedures and follow them as required
• Maintain store cleanliness, following proper sanitation guidelines
• Complete daily tasks, including stocking, inventory, and cleaning
• Follow Van Leeuwen's established safety, grooming, uniform, and employee conduct standards

JOB REQUIREMENTS

• Must be 18 years of age or older 
• Genuine passion for ice cream and desserts
• Possess dexterity to prepare and serve guests all menu items in accordance with established service and build-out standards
• Able to push/pull/lift 50 lbs of weight regularly
• Stand for extended periods of time regularly
• Walk up and down stairs regularly 
• Stand, bend and reach for prolonged periods of time
• Ability to thrive in a fast-paced environment
• Available to work 3 days a weeks (including nights and weekends past 12 am)
• Reliable, on time and ready for every shift
• Food handlers certificate required

WHY VAN LEEUWEN?

• Competitive Pay + Tips 
• Flexible Scheduling
• Free Ice Cream (One menu-item while on shift)
• Positive team environment
• Career development and growth opportunities
• Opportunity to be part of a growing, fun brand!

Why Join Us?

As a member of the Parabilis Medicines team, you will be a part of an organization dedicated to creating extraordinary medicines for diseases with urgent unmet needs, harnessing our proprietary peptide platform to transform treatment possibilities for patients. Parabilis is a clinical-stage biopharmaceutical company dedicated to unlocking high-impact protein targets long-considered undruggable. The company has developed a new class of stabilized, cell-penetrant alpha-helical peptides – Helicons™ – capable of modulating intracellular proteins that are inaccessible to traditional drug modalities.

Headquartered in Cambridge, Mass., Parabilis is advancing a focused pipeline of multiple first-in-class therapies across both rare and common cancers. Its lead asset, zolucatetide (FOG-001), is a first-in-class, clinically validated direct inhibitor of the interaction between β-catenin and the T-cell factor (TCF) family of transcription factors, implicated in millions of cancer cases annually, including in colorectal cancer, desmoid tumors, hepatocellular carcinoma and a range of other Wnt/β-catenin-driven tumors. In Phase 1 clinical trials, zolucatetide produced the first-ever clinical evidence that it can directly inhibit this interaction, once previously considered “undruggable” despite its role across multiple cancer types. Parabilis is also advancing investigational degraders of ERG and ARON into clinical development for the treatment of prostate cancer, as well as progressing other preclinical programs. Backed by a recent $305 million Series F financing, Parabilis is entering an exciting phase of growth and execution.

What’s the opportunity?

We are seeking an experienced leader in vivarium and in vivo operations to oversee our research animal facilities and in vivo study support. In this Associate Director role, you will be accountable for daily operations, resource planning, budgets, technical training and compliance with IACUC, AAALAC and institutional policies. 

You will manage animal procurement, housing, husbandry services and technicalsupport across discovery and pre‑clinicalstudies, collaborating with program leaders and CRO partnersto align operationalsupport with scientific objectives. A key aspect of this role is developing and coaching a high‑performing technical team while driving operational excellence and continuous improvement to uphold the highest standards of animal welfare.

Key abilities of this role include:

• Provide strategic and operational leadership for vivarium operations, ensuring high-quality husbandry, facility maintenance, and resource planning.
• Serve as institutional lead for IACUC protocols and animal use compliance; prepare and lead facility audits and inspections.
• Oversee procurement and inventory of animals and supplies and maintain accurate records of census and environmental conditions.
• Develop and manage the vivarium operating budget, forecasting resource needs and supporting capital planning. 
• Provide oversight and coordination of in vivo hands on training and SOP adherence for a cross functional group of hybrid scientists; remain willing to perform hands on work as needed and lead the integration of new skills and techniques as our portfolio and programs expand. 
• Coordinate study scheduling and operational support across in vivo pharmacology programs and CRO partners; represent in vivo operations in cross-functional meetings.
• Drive process improvement, SOP development and emergency preparedness; ensure compliance with AAALAC and institutional policies.
• Provide subject matter expertise in in vivo study execution, facility operations, and support program teams by troubleshooting logistics.

What you’ll need to be successful:

• Bachelor’s or master’s degree in biological sciences, animal science or related discipline; 10+ years of vivarium/in vivo experience including 5+ years in a leadership role; advanced degree (M.S., DVM or Ph.D.) and AALAS/CMAR certification are preferred.
• Demonstrated success managing vivarium operations, including budgets, resource forecasting, animal procurement and facility maintenance.
• In depth knowledge of AAALAC and IACUC regulations and experience serving as institutional lead for animal use protocols and facility audits.
• Proven ability to supervise, mentor, and develop technical staff and maintain high standards of animal welfare and safety.
• Strong operational planning, problem-solving and process improvement skills, with experience developing SOPs and emergency plans. 
• Excellent communication and interpersonal skills and ability to collaborate across cross functional program teams and with CRO partners.
• Ability to thrive in a fast paced, collaborative environment, work on site and participate in weekend or holiday coverage as needed.

Core Values

Parabilis Medicines is a team of passionate pioneers who are trailblazing the future of precision medicine with the aim of making a meaningful difference in the lives of patients. The company is committed to promoting an inspiring and flourishing working environment for all employees across the business, in all departments, and driving innovation for patient benefit.

• Growth-Minded. We’re inventing a new class of medicines—one applicable to therapeutic targets that have been dreamt about, but always considered impossible to drug. Our work requires us to be curious, humble and adaptable.
• In(ter)dependent. We are fiercely independent as a leader in defying the limitations of current therapeutic modalities, and interdependent as a team as we work collaboratively to shift drug discovery paradigms and provide patients with better treatment options.
• Patient-focused. We are deeply focused on patient outcomes, and all energy in the company is focused on science as it translates to patient impact.
• All-In. We’re All-In on solving some of the hardest scientific challenges and delivering one of the most effective new classes of drugs in history.

The base salary range for this position is $165,000-$200,000, depending on experience, qualifications, and internal practices. Parabilis’s total compensation package also includes an annual target bonus, equity, and a comprehensive suite of competitive benefits designed to support our employees’ overall well-being.

As an equal opportunity employer, Parabilis Medicines values an inclusive workplace and welcomes applicants of all backgrounds and experiences. All qualified applicants will receive consideration for employment without discrimination on the basis of race, color, religion, sex, sexual orientation, gender identity, national origin, protected veteran status, disability, or any other factors prohibited by law.

30 Acorn Park Drive    |     Cambridge, MA 02140    |    www.parabilismed.com

COMPANY DESCRIPTION

Flagship Pioneering is a platform innovation company that invents and builds companies that change the world. We bring together the greatest scientific minds with entrepreneurial company builders and assemble the capital to allow them to take courageous leaps. Those big leaps in human health, sustainability and beyond exponentially accelerate scientific progress in areas ranging from disease detection and treatment and nature-positive agriculture to novel applications of AI that are driving the creation of new technologies.   

What sets Flagship apart is our ability to advance science and technology by uniting innovation, company creation, and capital investment under one roof in a way that is largely without precedent. Our scientific founders, entrepreneurial leaders, and professional capital managers are each aligned around an institutionalized process that enables us to innovate and transform for the benefit of people and planet.   

Many of the companies Flagship has founded have addressed humanity’s most urgent challenges: vaccinating billions of people against COVID-19, curing intractable diseases, improving human health, preempting illness, and feeding the world by improving the resiliency and sustainability of agriculture.  

Flagship has been recognized twice on FORTUNE’s “Change the World” list, an annual ranking of companies that have made a positive social and environmental impact through activities that are part of their core business strategies and has been twice named to Fast Company’s annual list of the World’s Most Innovative Companies. 

THE ROLE

This role will support formulation development and laboratory operations with a primary focus on executing hands-on processing, analytical testing, and sample management activities for dried powder and liquid formulations. The Contract Lab Technician will work closely with the formulations team to support routine laboratory activities, in-process testing, microbiological assays, and fill/pack operations. Work Schedule: This position requires availability for one of the following shifts, Monday through Friday: 6:00 AM–2:00 PM or 11:00 AM–7:00 PM.

KEY RESPONSIBILITIES

1. Spray Dryer Operation & Maintenance

• Operate spray drying equipment in accordance with established protocols
• Monitor process parameters to ensure consistent and safe operation
• Perform routine cleaning and basic maintenance of the spray dryer and
• associated instruments
• Maintain a clean and organized workspace, adhering to safety and quality standards

1. Formulation Preparation

• Aliquot and prepare liquid formulations according to defined recipes and
• protocols
• Accurately measure and mix components while maintaining proper
• documentation
• Ensure proper labeling and handling of all materials

1. Sample Handling & Logistics

• Coordinate packaging, shipment, and receipt of samples to and from CROs and
• CMOs
• Maintain accurate records of sample inventory, shipment status, and chain of
• custody
• Ensure compliance with shipping and handling requirements

1. Fill & Pack Operations

• Execute fill and pack procedures for both powdered and liquid products
• Follow standard protocols for packaging, labeling, and storage
• Perform basic quality checks to ensure product consistency and integrity

General Expectations

• Adhere to all safety, quality, and documentation standards
• Follow standard operating procedures (SOPs) and escalate any deviations
• Support team operations to ensure efficient and reliable process execution

PROFESSIONAL EXPERIENCE & QUALIFICATIONS 

• High school diploma or associate degree in biology, chemistry, biotechnology, microbiology, or a related technical field.
• 1+ years of laboratory, manufacturing, or process operations experience preferred.
• Experience following SOPs and maintaining accurate laboratory records.
• Ability to safely handle laboratory chemicals, powders, and biological materials.
• Strong organizational skills and attention to detail.
• Ability to work independently and collaboratively in a team environment.
• Comfortable standing for extended periods and handling routine laboratory tasks.

LOCATION:  Cambridge, MA

ABOUT FLAGSHIP PIONEERING:

Flagship Pioneering invents and builds platform companies, each with the potential for multiple products that transform human health, sustainability and beyond. Since its launch in 2000, Flagship has originated more than 100 companies. Many of these companies have addressed humanity’s most urgent challenges: vaccinating billions of people against COVID-19, curing intractable diseases, improving human health, preempting illness, and feeding the world by improving the resiliency and sustainability of agriculture.  

Flagship has been recognized twice on FORTUNE’s “Change the World” list, an annual ranking of companies that have made a positive social and environmental impact through activities that are part of their core business strategies and has been twice named to Fast Company’s annual list of the World’s Most Innovative Companies. Learn more about Flagship at www.flagshippioneering.com.

At Flagship, we accept impossible missions to enable bigger leaps. Our core values guide us through uncertainty and toward lasting impact.

We are an equal opportunity employer. All qualified applicants will be considered for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, disability, protected veteran status, or any other characteristic protected by law.

We recognize that great candidates often bring unique strengths without fulfilling every qualification. If you have some of the experience listed above but not all, please apply anyway. We are dedicated to building diverse and inclusive teams and look forward to learning more about your background and interest in Flagship.

Recruitment & Staffing Agencies: Flagship Pioneering and its affiliated Flagship Lab companies (collectively, “FSP”) do not accept unsolicited resumes from any source other than candidates. The submission of unsolicited resumes by recruitment or staffing agencies to FSP or its employees is strictly prohibited unless contacted directly by Flagship Pioneering’s internal Talent Acquisition team. Any resume submitted by an agency in the absence of a signed agreement will automatically become the property of FSP, and FSP will not owe any referral or other fees with respect thereto.

#LI-TL1

The salary range for this role is $24 - $30. Compensation for the role will depend on a number of factors, including a candidate’s qualifications, skills, competencies, and experience. FL112 currently offers healthcare coverage, annual incentive program, retirement benefits and a broad range of other benefits. Compensation and benefits information is based on FL112's good faith estimate as of the date of publication and may be modified in the future.

About the Role:

Stylus Medicine is seeking a highly motivated and collaborative Senior Scientist to join our in vivo Pharmacology team. This role will be responsible for leading NHP studies, including working closely with CROs to manage studies, contribute to protocol writing and design, obtain, quality control, analyze and interpret data, lead investigative technical troubleshooting, ensure consistency in execution across studies, and create detailed and thorough study summaries. Reporting to the Director of in vivo Pharmacology and working closely with cross-functional teams, this is a unique opportunity to contribute to foundational development in a fast-paced, cutting-edge biotech environment and advance the development of transformative in vivo genetic medicines.

Key Responsibilities & Accountabilities: 

• Design NHP study protocols and lead CRO communication
• Analyze, interpret, and communicate NHP study data, including flow cytometry analysis, cytokine analysis and other ex vivo readouts, to inform project direction and decision-making
• Evaluate data for consistency and follow-up as needed, working closely with CROs to optimize study protocols
• Investigate and interpret biological findings from NHP studies
• Manage NHP study test article generation and transfer in collaboration with internal cross-functional teams
• Conduct experiments to optimize protocols for CRO transfer or investigate biological findings
• Generate and manage study documentation, including protocols and study reports
• Effectively communicate findings to internal teams.
• Maintain detailed and accurate laboratory records in compliance with data integrity and documentation standards
• Limited travel may be required

 Qualifications & Skills:

• PhD in Pharmacology, Immunology, Immuno-oncology, or a related field with 4-6 years of relevant industry or academic experience, or a Master's degree with 8+ years of experience
• Demonstrated experience with ex vivo analytical techniques, such as flow cytometry, cytokine analysis, and ddPCR
• Demonstrated ability to design, execute, interpret, and troubleshoot immunology-related in vivo studies and to coordinate the activities of multiple study contributors
• Experience coordinating with animal vendors, CROs or external collaborators
• Prior experience with NHP studies is preferred
• Experience in designing experiments to address PK/PD/biodistribution/tox relationships is a plus
• Experience with LNP or CART delivery technologies and genetic medicine platforms is a plus
• Experience with T cell or PBMC isolation and handling from peripheral blood, engineering, and downstream immunological or molecular assays
• Demonstrated ability to work independently in a laboratory setting, learn new techniques, multitask effectively, and maintain meticulous records
• Demonstrated proficiency in documenting and maintaining an organized lab notebook, lab inventory, and experimental results
• Excellent organizational and communication skills, with a team-first mindset and the ability to convey technical information
• Analytical thinker with the ability to distill complex data into clear, actionable insights

Pay Range: $160,000 - $175,000

About the Role: Nanopath is seeking a Laboratory Technician that will be responsible for the day-to-day experimental support and laboratory operations.

• Execute established SOPs in support of Nanopath R&D team.
• Support R&D teams experimental needs by preparing key components, buffers, and other materials to enable high-throughput experimentation.
• Ensure quality of incoming materials by performing quality inspections though documentation review and/or initial testing.
• Independently conduct stability studies for key materials.
• Assist engineering team with routine manufacturing of diagnostic consumable.
• Oversee routine lab management, inventory management, consumable ordering and stocking, and occasional equipment maintenance.

Desired Qualifications:

• Bachelor’s degree in biology or chemistry with 2+ years of industry experience working in a laboratory OR Associate’s Degree with 4+ years of industry experience.
• Experience working in biological laboratories with ability to repeatably execute experiments using established protocols.
• Extremely well-organized with a high level of efficiency, attention to detail, and motivation for completing tasks accurately and on time.
• Excellent communication, written, and presentation skills.
• Passionate about Nanopath’s mission for developing a purpose-built solution for women’s health.
• Lab management experience preferred.

Prime Medicine was founded to bring the promise of gene editing to patients. We use Prime Editing, a next-generation technology that can “search and replace” to restore normal genetic function almost anywhere in the genome. Prime Editing searches to find the precise place in the genome to edit and replaces the segment of faulty DNA with a correct copy of DNA.  A single Prime Editor can correct the individual mutations found across patients, meaning Prime Editing can potentially address more than 90 percent of known disease-causing genetic mutations. 

We envision a world where this technology can cure, halt, and ultimately prevent genetic diseases, providing lifelong benefit to patients.  Prime Medicine offers the opportunity to shape the future of gene editing and transform how medicines are used to treat disease. Realizing the promise of Prime Editing requires a talented team with diversity of viewpoints and expertise. We’re building a group of dedicated, scientifically curious individuals who are passionate about helping patients live longer, healthier lives.

Position Overview

Prime Medicine is seeking a talented and motivated Sr. Manager to join the Analytical Development & QC team within Technology, Development & Operations. This role will focus on Quality Control (QC) related activities for all programs, including management and technical oversight of tech transfer, qualification/validation and release and stability testing carried out at both CDMOs, CTLs and internally at Prime for our prime editing ex vivo cell therapy and in vivo LNP-based drug products.

The successful candidate will have deep understanding of method lifecycle management, including method optimization, qualification, validation/verification, transfer, and implementation in a cGMP environment, as well as previous hands-on experience in at least some aspects of the above. This is a role requiring strong cross-functional collaboration with Analytical Development, Quality, Process Development, Formulation, Informatics, and external partners (CTLs/CDMOs). 

The ideal candidate thrives in a matrixed, fast-paced environment, works effectively with limited supervision, and demonstrates strong technical ownership and execution.

Key Responsibilities

• Design or review analytical procedures and protocols supporting method lifecycle activities, including optimization, qualification, validation, transfer, verification, performance monitoring, bridging, and comparability studies
• Manage and conduct select release, stability, and in-process testing for drug substances, drug products, and gene-editing components, and carry out data analysis and trending
• Support and/or manage analytical method transfer to CTLs/CDMOs, providing oversight, troubleshooting, and ensuring technical and timeline objectives are met
• Manage GMP sample inventory and chain-of-custody documentation
• Lead, manage and maintain well-designed stability programs and reference standard programs
• Author and review protocols, reports, SOPs, and analytical sections of regulatory submissions
• Familiarity with and ability to learn and use new tools for productivity, project management, documentation, tracking scheduling, and data management.
• Support IQ/OQ/PQ of QC equipment and ensure compliance with 21 CFR Part 11
• Maintain GxP-compliant electronic documentation and thorough laboratory records
• Collaborate with Quality to ensure data integrity, regulatory compliance, and audit readiness
• Lead or support investigations, deviations, and root-cause analyses
• Present data and findings to cross-functional teams
• Prepare technical reports and documents for global regulatory submissions

Qualifications

Education & Experience

• BS/MS/PhD in Biochemistry, Molecular biology, Chemistry, Bioengineering, or a related discipline
• Industry experience:
• BS: 10+ years
• MS: 8+ years
• PhD: 3+ years

Technical Expertise

• Experience with analytical method optimization, tech-transfer, qualification, validation, and verification used for critical components, drug substance and drug product release and stability testing
• Hands-on experience with analytical methodologies such as:
• Chromatography-based assays
• Absorbance-based assays
• Cell-based assays
• Compendial assays
• Molecular-based assays
• Flow cytometry assays
• Familiarity with ICH and FDA guidelines for CMC development during clinical stage is required
• Experience in advanced cell and gene-editing therapeutics development is not mandatory, but highly desirable
• Experience working with CMOs/CDMOs is required
• Experience with stability and/or reference standard programs is a plus
• Knowledge of assays, instrumentation, and facility qualification/validation requirements is desirable
• Familiarity with regulatory writing

Personal Attributes

• Highly self-motivated with strong project ownership
• Strong collaborator with internal cross-functional and external partners
• Adaptable in a dynamic, fast-paced environment
• Detail-oriented with strong troubleshooting and problem-solving skills
• Excellent written and verbal communication skills
• Strong abilities to lead and facilitate technical meetings with CDMO and CTL SMEs
• Work with purpose and drive meaningful results
• Ability to innovate and challenge industry status quo
• Ability to travel for up to 5 - 10% of the time

Prime Medicine is proud to be an equal opportunity employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, national origin, sexual orientation, gender identity, disability, protected veteran status, or any other characteristic protected by law.

Who We Are

Flagship Pioneering is a scientific innovation engine that invents and builds companies that change the world. We bring together the greatest scientific minds with entrepreneurial company builders and assemble the capital to allow them to take courageous leaps in human health, sustainability, and beyond. 

What sets Flagship apart is our ability to advance biotechnology by uniting life science innovation, company creation, and capital investment under one roof in a way that is largely without precedent. Our team of scientists, entrepreneurial leaders, and professional capital managers are each aligned around an institutionalized process that enables us to innovate and create breakthroughs for the benefit of people and planet.

Many of the companies Flagship has founded have addressed humanity’s most urgent challenges: vaccinating billions of people against COVID-19, curing intractable diseases, improving human health, preempting illness, and feeding the world by improving the resiliency and sustainability of agriculture.

Flagship has been recognized twice on FORTUNE’s “Change the World” list, an annual ranking of companies that have made a positive social and environmental impact through activities that are part of their core business strategies, and has been named four times to Fast Company’s annual list of the World’s Most Innovative Companies.

About the Role

Flagship's GRC program has matured from build to operate. We have a functioning GRC system of record in Jira, active compliance tracks across HITRUST, NIST 800-171, ISO 27001, and SOC 2, and a TPRM workflow in production. What we need now is a hands-on practitioner who can execute against that infrastructure — someone who is as comfortable running a vendor risk assessment in Jira as they are prepping evidence packages for an audit. This is not a policy-writing or director-level role. It is a technical execution role for someone who gets things done.

What You'll Do

• Own day-to-day execution of the GRC system of record in Jira — maintaining control records, updating compliance status, logging implementation and auditor notes, and keeping the SOR current across all active frameworks
• Run TPRM assessments end-to-end: intake, questionnaire review, risk scoring, CISO decision documentation, and post-approval tracking
• Coordinate audit evidence collection and control testing activities across HITRUST, ISO 27001, SOC 2, and NIST 800-171 frameworks, working directly with the external audit firm
• Maintain the compliance calendar and drive sprint-by-sprint execution against framework deadlines
• Manage sub-processor and DPA tracking for portfolio company privacy programs, including gap identification and remediation follow-up
• Support DSR and privacy program operations, including data inventory maintenance and deletion workflow tracking
• Build and maintain GRC automation using AI tools (Claude, Jira automation, Zapier) to reduce manual burden on recurring compliance tasks
• Produce clear, accurate reporting on compliance posture for the CISO and cross-functional stakeholders

What We're Looking For

• 3–6 years of hands-on GRC experience, ideally in a fast-moving tech or life sciences environment
• Direct experience working in Jira as a compliance or GRC tool — not just a project management tool; you should understand issue types, custom fields, bulk operations, and reporting
• Working knowledge of at least two of: HITRUST CSF, ISO 27001, NIST 800-171/CMMC, SOC 2, HIPAA
• Experience running vendor risk assessments — intake to decision — not just filling out questionnaires
• Comfort with AI-assisted work: you should already be using tools like Claude or ChatGPT to accelerate your GRC work, not learning to do so for the first time
• Strong written communication — you'll be producing evidence narratives, audit responses, and control documentation that external auditors and regulators will read
• Ability to operate with high autonomy; the CISO will provide direction but not day-to-day supervision

Nice to Have

• CISA, CRISC, CISM, or equivalent certification
• Experience with privacy program operations (CCPA, GDPR, DSR workflows)
• Familiarity with Drata, Vanta, or similar compliance automation platforms
• Experience supporting a portfolio company or multi-entity compliance program

Why This Role

You'll own a real compliance program, not support someone else's. The CISO is your direct partner, not a distant approver. You'll use modern tools — Jira, Claude, Zapier — to do GRC work that most teams still do in spreadsheets. And you'll have visibility into a genuinely diverse security environment spanning drug discovery AI, clinical platforms, and life sciences infrastructure.

We are an equal opportunity employer. All qualified applicants will be considered for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, disability, protected veteran status, or any other characteristic protected by law. 

We recognize that great candidates often bring unique strengths without fulfilling every qualification. If you have some of the experience listed above but not all, please apply anyway. We are dedicated to building diverse and inclusive teams and look forward to learning more about your background and interest in Flagship. 

Recruitment & Staffing Agencies: Flagship Pioneering and its affiliated Flagship Lab companies (collectively, “FSP”) do not accept unsolicited resumes from any source other than candidates. The submission of unsolicited resumes by recruitment or staffing agencies to FSP or its employees is strictly prohibited unless contacted directly by Flagship Pioneering’s internal Talent Acquisition team. Any resume submitted by an agency in the absence of a signed agreement will automatically become the property of FSP, and FSP will not owe any referral or other fees with respect thereto. 

#LI-NM1 

The salary range for this role is $88,000 - $121,000. Compensation for the role will depend on a number of factors, including a candidate’s qualifications, skills, competencies, and experience. Flagship Pioneering currently offers healthcare coverage, annual incentive program, retirement benefits and a broad range of other benefits. Compensation and benefits information is based on Flagship Pioneering's good faith estimate as of the date of publication and may be modified in the future.

Why Join Us?

Parabilis Medicines is a clinical-stage biopharmaceutical company dedicated to creating extraordinary medicines that unlock high-impact protein targets long-considered undruggable. The company has developed a new class of stabilized, cell-penetrant alpha-helical peptides – Helicons™ – capable of modulating intracellular proteins that are inaccessible to traditional drug modalities. 

Headquartered in Cambridge, Mass., Parabilis is advancing a focused pipeline of multiple first-in-class therapies across both rare and common cancers. Its lead asset, zolucatetide (FOG-001), is a first-in-class, clinically validated direct inhibitor of the interaction between β-catenin and the T-cell factor (TCF) family of transcription factors, implicated in millions of cancer cases annually, including in colorectal cancer, desmoid tumors, hepatocellular carcinoma and a range of other Wnt/β-catenin-driven tumors. In Phase 1 clinical trials, zolucatetide produced the first-ever clinical evidence that it can directly inhibit this interaction, once previously considered “undruggable” despite its role across multiple cancer types. Parabilis is also advancing investigational degraders of ERG and AR^ON into clinical development for the treatment of prostate cancer, as well as progressing other preclinical programs. Backed by a recent $305 million Series F financing, Parabilis is entering an exciting phase of growth and execution.

What’s the opportunity?

The Senior Manager, Supply Chain will lead the end-to-end operational management of investigational product (IP) and clinical trial materials across global Phase I–III studies. This role is responsible for ensuring timely, compliant, and efficient delivery of clinical supplies, while partnering cross-functionally with Clinical Operations, Quality, Regulatory, CMC, and external vendors to support study execution.

• Develop and maintain study-level supply plans and forecasts aligned with enrollment, protocol design, and site activation timelines
• Coordinate packaging, labeling, release, and global distribution of investigational products and ancillary materials
• Oversee inventory across depots and study sites, proactively mitigating risks to avoid shortages or excess
• Serve as business owner of the IRT system, including setup, configuration, validation, and ongoing management
• Partner cross-functionally to align supply strategy with clinical and regulatory requirements and ensure seamless execution
• Author and maintain supply-related documentation, including SOPs, Pharmacy Manuals, and study-specific materials
• Ensure compliance with GxP, GDP, and ICH-GCP standards, supporting audits and inspection readiness
• Manage global logistics, vendor oversight, and third-party partners to ensure uninterrupted supply across regions

What you’ll need to be successful:

• Bachelor’s degree in Supply Chain, Life Sciences, or related field (Master’s preferred)
• Minimum 5 years of global clinical supply chain experience within biotech, pharma, or medical device
• Hands-on experience with IRT/IXRS systems (e.g., 4G Clinical, Almac, Endpoint)
• Experience supporting global Phase I–III clinical trials (commercial launch experience preferred)
• Proficiency with Microsoft Office and inventory/ERP systems
• Strong understanding of GxP, GDP, and ICH-GCP regulations
• Proven ability to manage complex global supply operations and mitigate risk
• Strong analytical, organizational, and problem-solving skills
• Effective cross-functional collaboration and communication across internal teams and external partners
• Experience drafting SOPs, Pharmacy Manuals, and clinical supply documentation preferred
• Familiarity with cold chain and temperature-controlled distribution preferred
• APICS/CSCP or PMP certification a plus
• Demonstrated ability to utilize AI tools for day-to-day work; baseline proficiency is expected, and advanced or innovative use of AI is a strong plus
• Able to work on-site and attend in-person meetings
• Ability to travel up to 15%

Core Values

Parabilis is a team of passionate pioneers who are trailblazing the future of precision medicine with the aim of making a meaningful difference in the lives of patients. The company is committed to promoting an inspiring and flourishing working environment for all employees across the business, in all departments, and driving innovation for patient benefit.

• Growth-Minded. We’re inventing a new class of medicines—one applicable to therapeutic targets that have been dreamt about, but always considered impossible to drug. Our work requires us to be curious, humble and adaptable.
• In(ter)dependent.We are fiercely independent as a leader in defying the limitations of current therapeutic modalities, and interdependent as a team as we work collaboratively to shift drug discovery paradigms and provide patients with better treatment options.
• Patient-focused.We are deeply focused on patient outcomes, and all energy in the company is focused on science as it translates to patient impact.
• All-In.We’re All-In on solving some of the hardest scientific challenges and delivering one of the most effective new classes of drugs in history.

The base salary target for this position is $153,000-$180,000 per year, depending on experience, qualifications, and internal practices. Parabilis’s total compensation package also includes an annual target bonus, equity, and a comprehensive suite of competitive benefits designed to support our employees’ overall well-being.

As an equal opportunity employer, Parabilis values an inclusive workplace and welcomes applicants of all backgrounds and experiences. All qualified applicants will receive consideration for employment without discrimination on the basis of race, color, religion, sex, sexual orientation, gender identity, national origin, protected veteran status, disability, or any other factors prohibited by law.

30 Acorn Park Drive    |     Cambridge, MA 02140    |    www.parabilismed.com

Your Impact at LILA

Lila is building AI Science Factories (AISFs) — highly automated, AI-directed labs that generate the proprietary experimental data powering our AI platform. As we scale from one AISF to many, the operational infrastructure that keeps those factories running is a first-class strategic capability.

The Director of Lab Operations & Maintenance Management (LOMM) owns the physical and logistical foundation of Lila's science operations: consumables and reagent supply chains, equipment asset management, CMMS management, waste coordination, space readiness, preventative maintenance (PM), first response equipment/instrument demand maintenance, and multi-shift logistics continuity.

This role will build out and manage Lila's Maintenance Management (MM) function from the ground up — hiring the initial team, developing best practices, and establishing the operational handoff as we mature and scale.

But this role is as much about building these systems as running them — you'll define the LOMM operating model, lead its expansion to new sites, drive AI-enabled innovation in how we manage lab resources, and author the standards that travel with every AISF we open.

You'll operate as a recognized authority on lab operations within Lila, partnering directly with VPs and senior leaders across Autonomous Science Platform (ASP), Finance, EHS, and Facilities. You'll be a principal contributor to the Blueprint program — the global deployment framework that defines how Lila builds and runs AI Science Factories at scale.

What You'll Be Building

Lab Operations Strategy & Operating Model

• Define and own the LOMM operating model across Lila sites — from single-shift pilot to multi-site, continuous operations
• Establish the systems, org structure, staffing model, and governance framework that enable LOMM to scale reliably
• Set and track operational KPIs (inventory accuracy, stockout rate, PM scheduling compliance, asset data integrity, ticket resolution time); use data to drive structured improvement cycles and report trends to ASP leadership

Consumables, Reagents & Supply Chain

• Own end-to-end supply chain continuity for all lab consumables, reagents, and PPE across all shifts and sites
• Design and govern the par-level inventory system, reorder triggers, cold storage management, and expiry tracking infrastructure
• Lead dual-source qualification strategy for high-risk consumables; build the satellite site supply chain playbook for future AISFs in support of the Blueprint project

CMMS & Equipment Asset Management

• Own CMMS strategy, selection, implementation, and long-term governance — accountable for data accuracy across all commissioned instruments and mobile assets
• Define asset tagging standards and location tracking protocols in alignment with Blueprint's asset taxonomy
• Own PM coordination across sites; ensure calibration access and instrument readiness for production operations

Maintenance Management— Build & Oversight

• Build out the Maintenance Management function from scratch in collaboration with Hardware & Controls Engineering (HCE) team: define the team structure, hire initial MM staff, and establish the operating model for instrument PM, calibration, and first-response troubleshooting
• Stand up a dedicated L1 (Level 1) maintenance support team as the first line of response for lab-floor issues across shifts: triage incoming requests, execute standard work (resets, swaps, basic mechanical/electrical checks, consumables replenishment for instruments as defined), and escalate efficiently to HCE- L2/L3 Sustaining Engineering, vendors, or Integration Automation Engineering when deeper troubleshooting or design changes are required
• Establish the escalation and handoff protocols between MM, LabOps, Research Operations (production team), and HCE/Automation; define the boundary between maintenance of commissioned instruments that are best serviced by MM and engineering modifications
• Explore and define the HCE onboarding/training model for MM technicians, including potential rotational program for cross-training and augmentation

AI Integration & Continuous Improvement

• Lead Lila's thinking on AI-enabled lab operations — evaluate, pilot, and scale intelligent solutions across inventory management, predictive reordering, asset tracking, and operational reporting
• Build a continuous improvement culture within LOMM: baseline metrics, run structured improvement cycles, and bring external best practices from the biotech/life sciences industry into Lila's operating model
• Define the innovation roadmap for LOMM in partnership with engineering and operations teams

Vendor & Logistics Management

• Own vendor relationships for all lab supplies and logistics within approved frameworks; partner with Finance on contract strategy for key suppliers
• Oversee lab-side receiving, intake, space readiness for new instrument deployments, waste and hazmat scheduling, gas management, and cold storage operations
• Manage LOMM support ticket system as the single intake for all lab supply, equipment, and space requests

Team Leadership

• Lead, grow, and develop the LOMM team across shifts and sites, scaling with each new site and shift expansion
• Build and lead the MM team as a direct report function — from first hire through a fully operational multi-site MM capability
• Define staffing models, hiring roadmaps, and capability development plans for both functions as they mature
• Build a team culture defined by operational rigor, proactive problem-solving, and continuous improvement

Blueprint Contribution & Multi-Site Scaling

• Author and own the LOMM chapter of Blueprint — documenting processes, system requirements, staffing models, and vendor frameworks so LOMM scales reliably to every new AISF
• Pilot the Site Launch Readiness Scorecard for each new facility; feed findings back into Blueprint standards
• Define the LOMM readiness criteria and pre-commissioning checklist for all future site launches

What You’ll Need to Succeed

• 12–15+ years of lab operations experience in a biotech or life sciences environment, with demonstrated strategic impact at the program or portfolio level
• Proven track record of defining and scaling lab operations systems — not just inheriting and running them; you've built operating models, established governance, and led functions through significant growth
• Deep expertise in CMMS selection, implementation, and governance — you've owned platform decisions and data accuracy programs, not just used the tool
• Experience building and leading teams across multiple functions, shifts, or sites — including hiring from scratch and developing operational capability in parallel with day-to-day execution
• Experience owning and successfully defending ISO 9001:2015 audits related to preventive maintenance (PM) and calibration programs (e.g., evidence packages, CAPAs, and auditor-facing readiness)
• Recognized as an authority in lab operations within your organization; comfortable operating as a peer to VPs and senior leaders and representing your function externally
• Strong strategic and systems-level thinking — you anticipate org-wide operational challenges and define the structures to solve them, not just the immediate fix

Bonus Points For

• Experience building or overseeing a Maintenance Management or instrument PM function — familiarity with IQ/OQ/PQ, calibration registries, MTBF tracking, and service vendor management
• Experience leading or partnering closely with field service / technical service teams (dispatch, SLAs, escalation models, parts logistics, and service performance management) in high-uptime environments
• Experience applying AI or intelligent automation to lab operations workflows (e.g., predictive inventory, automated asset tracking, AI-assisted reporting)
• Background in materials science, life science, and chemistry lab environments — familiarity with the specific consumables, reagents, handling requirements, and vendor landscape in those domains
• Experience supporting multi-shift or 24/7 lab operations
• Familiarity with QMS-adjacent environments (SOP document control, change control, training records)
• Experience contributing to a global site deployment or standardization program (playbook authorship, site launch readiness frameworks)

Your Impact at LILA

We’re seeking a Head of Supply Chain & Strategic Sourcing to design and scale the function that keeps our scientific platform moving. You’ll own sourcing, procurement, vendor management, inventory, and payments with responsibility for hundreds of millions in annual spend across scientific equipment, lab operations, consumables, and technology infrastructure.

This role sits at the intersection of science, engineering, and finance. You’ll work closely with R&D, engineering, and AI research teams to ensure material availability, supplier performance, cost optimization, and operational resilience. If you’ve built procurement functions in environments where the stakes are high and the pace is fast whether in biotech, AI infrastructure, advanced materials, or hardware this is the role for you.

What You'll Be Building

• Design and scale the end-to-end Procure-to-Pay (P2P) process: sourcing strategy, purchasing channels, vendor governance, and payment operations.
• Lead strategic sourcing: supplier selection, contract negotiations, and ongoing vendor management.
• Build scalable supply chain infrastructure to support complex labs, capital equipment programs, specialized materials, and evolving R&D needs.
• Implement and optimize ERP/P2P systems, automation, and operations (procurement tools, AP workflows, controls).
• Create KPIs and dashboards to drive cost savings, supplier performance, and working capital optimization.
• Establish governance, policies, internal controls, and scalable systems for compliance and audit readiness.
• Centralize procurement operations to align purchasing, payments, leasing, and working capital management.

What You’ll Need to Succeed

• 10+ years of progressive leadership in procurement, supply chain, or P2P operations.
• Experience building or transforming supply chain/P2P in a high-growth setting.
• Experience in biotech, life sciences, AI, advanced materials, or hardware-enabled environments.
• Deep knowledge of ERP and procurement systems (examples: NetSuite, Coupa, Ariba, Ramp; familiarity with Prendo if applicable).
• Proven success negotiating complex supplier agreements and driving cost optimization.
• Experience leading cross-functional teams through rapid growth in spend and headcount.
• Experience implementing modern procurement or ERP systems to replace legacy infrastructure.
• Experience overseeing leasing and equipment financing aligned with capital strategy.

Bonus Points For

• Familiarity with public-company readiness, SOX compliance, and audit environments.
• Experience developing equipment leasing and financing strategies to optimize capital deployment and cash flow.
• Relevant certifications (e.g., MBA, CPIM, CPSM) or equivalent experience.

Your Impact at LILA

We are seeking a highly organized and proactive Administrative Coordinator to provide operational and administrative support to our Government Affairs team in Washington, D.C. This role is the operational backbone of the team and ensuring the Government Affairs office can focus on its core efforts. The ideal candidate is a self-starter who thrives in a fast-paced, politically dynamic environment and exercises sound judgment and discretion at all times. This role requires 5 days a week in office in Washington, DC.

What You'll Be Building

GA Team Support 

• Manage scheduling for government affairs team, including scheduling meetings with Members of Congress, agency officials, and coalition partners
• Coordinate domestic and international travel logistics, including flights, hotels, ground transportation, and itineraries
• Prepare and process expense reports, invoices, and reimbursements in a timely manner
• Draft, proofread, and edit correspondence, briefing materials, talking points, and internal memos
• Anticipate executive needs and proactively handle administrative matters with minimal direction

Office Management

• Oversee day-to-day office operations, serving as the primary point of contact for building management, vendors, and service providers
• Manage office supply inventory, equipment maintenance, and facilities needs
• Onboard new team members, including coordinating workspace setup, badge access, and IT provisioning
• Maintain organized filing systems for legislative documents, regulatory filings, lobbying disclosures, and compliance records
• Coordinate with IT support to troubleshoot technology issues and manage software subscriptions

Legislative & Government Affairs Support 

• Assist with the preparation and timely filing of lobbying disclosure reports (LDA filings) in coordination with compliance counsel
• Maintain and update contact databases for congressional offices, agency contacts, and external stakeholders
• Coordinate logistics for Capitol Hill meetings, fly-ins, briefings, receptions, and fundraising events with external consultants
• Support the preparation of leave-behinds, one-pagers, and materials for Congressional meetings

Events & Stakeholder Coordination

• Plan and execute team events, including staff retreats, coalition meetings, roundtables, and receptions
• Manage coordination including invitations, RSVPs, catering, AV setup, and venue coordination
• Liaise with external partners, trade associations, and consulting firms on joint events and initiatives

What You’ll Need to Succeed

• 3–5 years of experience in an executive assistant, office manager, or administrative role, preferably in public service, government affairs, lobbying, law, or public policy environment
• Strong familiarity with the Washington, D.C. political landscape, including how Congress and federal agencies operate
• Exceptional organizational skills with the ability to manage multiple priorities under tight deadlines
• Outstanding written and verbal communication skills
• High degree of professionalism, discretion, and judgment when handling sensitive or confidential information
• Proficiency in Microsoft Office Suite (Outlook, Word, Excel, PowerPoint) and collaboration tools (e.g., Teams, Zoom, Slack)
• Ability to travel up to 10% of the calendar year, including international travel
• Ability to be in office 5 days a week in Washington, DC

Preferred

• Experience supporting C-suite executives or senior government officials
• Familiarity with Lobbying Disclosure Act (LDA) compliance and reporting requirements
  • Experience with stakeholder or contact management platforms (e.g., Quorum, Fireside, Salesforce)
  • Familiarity with political giving processes, including PAC administration, contribution tracking, and FEC reporting requirements
• Bachelor's degree in political science, public policy, communications, business, or a related field

Bonus Points For

• Discretion & Professionalism — Handles sensitive political and organizational information with the utmost confidentiality
• Proactive Problem-Solving — Anticipates issues and resolves them before they escalate
• Attention to Detail — Produces accurate, polished work products consistently
• Adaptability — Remains calm and effective in a dynamic, high-stakes environment
• Relationship Management — Builds trusted relationships with internal stakeholders, congressional staff, and external partners

Title:                   Contract - Senior Quality Control Specialist

Location:           Cambridge, MA - onsite

Reports to:        Senior Manager, Quality Control

About Vedanta Biosciences:

Vedanta Biosciences is a late-stage biopharmaceutical company developing medicines for the treatment of gastrointestinal diseases. The company’s lead assets include potential first-in-class oral therapy, VE303, in a Phase 3 trial for recurrent C. difficile infection. Vedanta’s pipeline has been built using the company’s industry-leading product engine for the development of therapies based on defined consortia of bacteria grown from pure clonal cell banks. The product engine, supported by foundational IP, includes one of the largest libraries of bacteria isolated from the human microbiome, vast clinical datasets, proprietary capabilities in consortium design, and end-to-end CGMP manufacturing capabilities at commercial launch scale.

The Role:

This position directly supports Vedanta’s in-house cGMP manufacturing capabilities. This role will be lab-centered and focused on Drug Product and Drug Substance testing for release and stability. In addition to performing testing, this role will participate in the management of the Quality Control laboratory with daily responsibilities including routine lab testing, inventory management, and data reporting.

There will be collaboration with Analytical Development, Quality Assurance, and Production departments to support cGMP manufacturing, Process Validations, and Analytical Testing Validations.

A successful candidate for this role will have strong attention to detail, good organizational skills, and be a quick learner. They will be able to exercise judgment within defined procedures and practices to determine appropriate action and ask questions if the path forward is unclear, follow routine procedures, apply learned techniques, and contribute to analysis and investigation to solve problems. An ideal candidate will be a strong independent worker, able to self-organize and execute day-to-day work autonomously.

Previous experience with hands-on laboratory testing in a microbiology laboratory, aseptic technique, qPCR, pipetting, and general USP microbiological is required. Experience with chemistry testing and data review preferred.

This role will require being on-site full-time in Cambridge.

Here’s What You’ll Do:

• Perform routine microbiology testing to support release and stability of Vedanta products
• Perform testing to support assay validation activities
• Review test lab data, protocols, reports, and quality events (deviations, OOS etc.)
• Author, review, and revise SOPs, protocols, and reports
• Participate in continuous improvement projects to support the growth of the company
• Participate within the QC team to meet group and company goals

Requirements:

• BS in a scientific discipline
• Minimum 5+ years working in a GMP environment and/or Quality Control test lab
• Direct, hands on, experience with PCR/qPCR testing
• Direct experience with aseptic sampling and testing techniques
• Strong laboratory and organizational skills, attention to detail, flexibility, and the ability to work independently and within a team environment
• Experience working within QMS systems, deviation investigations, OOS, CAPAs and Change Controls
• Experience with QC continuous improvement projects; project management skills a plus
• Proficient in Outlook, MS Word, Excel, and lab-based data management systems
• Knowledge of FDA and EU compliance principles
• Knowledge of USP and ICH guidance preferred

The base pay range for this position is expected to be $46-53 per hour; however, the base pay offered may vary depending on market dynamics, experience, internal equity, and job-related knowledge, skills, and capabilities.

Company description

Serif Biomedicines is a privately held, early-stage biotechnology company developing a novel approach to gene therapy that can address currently untreatable diseases. It was founded by Flagship Pioneering, an innovation enterprise that conceives, creates, resources, and grows first-in-category life sciences companies.

Flagship Pioneering has created over 100 groundbreaking companies over the past twenty years, all of which are pioneering novel and proprietary biological, industrial, and engineering approaches to solve major needs in human health and sustainability. These companies include Moderna (MRNA), Syros Pharmaceuticals (SYRS), Seres Therapeutics (NASDAQ:MCRB), Generate Biomedicines, Tessera Tx, Evelo Biosciences (EVLO), and Indigo Agriculture.

The role

We are seeking a motivated Associate Scientist to support the development, preparation, and characterization of Lipid Nanoparticle (LNP) formulations. This role is highly hands-on and focused on formulating, screening, and analyzing LNPs to support discovery and development programs. The ideal candidate works well in a fast-paced, team-oriented environment and is eager to deepen their expertise in formulation science.

Key responsibilities

• Prepare and formulate LNPs using established protocols and evolving methods
• Execute formulation experiments to support optimization and screening efforts
• Perform LNP characterization and analytics, including particle size, PDI, encapsulation efficiency, and stability testing
• Accurately document experimental procedures, results, and observations in laboratory records
• Analyze and summarize experimental data and communicate findings to project teams
• Collaborate closely with scientists across formulation, analytics, and biology functions
• Support routine laboratory operations, including reagent preparation, equipment upkeep, and inventory management

Professional experience and qualifications

• BS or MS in Chemistry, Biochemistry, Pharmaceutical Sciences, Chemical Engineering, or a related field and 8+ years of industry experience
• Hands-on experience with LNP formulations or lipid-based delivery systems
• Familiarity with LNP analytical techniques (e.g., DLS, encapsulation assays, basic stability studies)
• Strong attention to detail and ability to follow experimental protocols
• Ability to work effectively as part of a team in a fast-paced environment
• Good written and verbal communication skills

What We Offer

• Opportunity to work at the forefront of LNP formulation innovation
• Collaborative, science-driven culture with high impact research
• Competitive compensation and benefits package

LOCATION: Cambridge, MA

ABOUT FLAGSHIP PIONEERING

Flagship Pioneering invents and builds platform companies, each with the potential for multiple products that transform human health, sustainability and beyond. Since its launch in 2000, Flagship has originated more than 100 companies. Many of these companies have addressed humanity most urgent challenges: vaccinating billions of people against COVID-19, curing intractable diseases, improving human health, preempting illness, and feeding the world by improving the resiliency and sustainability of agriculture.

Flagship has been recognized twice on FORTUNE Change the World list, an annual ranking of companies that have made a positive social and environmental impact through activities that are part of their core business strategies and has been twice named to Fast Company annual list of the World Most Innovative Companies. Learn more about Flagship https://url.us.m.mimecastprotect.com/s/xLXBCqxk3LTk9pwcZf3CEkjif?domain=flagshippioneering.com.

At Flagship, we accept impossible missions to enable bigger leaps. Our core values guide us through uncertainty and toward lasting impact.

We are an equal opportunity employer. All qualified applicants will be considered for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, disability, protected veteran status, or any other characteristic protected by law.

Recruitment & Staffing Agencies: Flagship Pioneering and its affiliated Flagship Lab companies (collectively, “FSP”) do not accept unsolicited resumes from any source other than candidates. The submission of unsolicited resumes by recruitment or staffing agencies to FSP or its employees is strictly prohibited unless contacted directly by Flagship Pioneering’s internal Talent Acquisition team. Any resume submitted by an agency in the absence of a signed agreement will automatically become the property of FSP, and FSP will not owe any referral or other fees with respect thereto.

The salary range for this role is $96,000 - $126,500. Compensation for the role will depend on a number of factors, including a candidate’s qualifications, skills, competencies, and experience. Serif Biomedicines currently offers healthcare coverage, annual incentive program, retirement benefits and a broad range of other benefits. Compensation and benefits information is based on Serif Biomedicine's good faith estimate as of the date of publication and may be modified in the future.

Company Summary:

Serif Biomedicines, Inc. is a privately held, early-stage biotechnology company developing a novel approach to gene therapy that can address currently untreatable diseases.

Serif Biomedicines was founded by Flagship Pioneering, an innovation enterprise that conceives, creates, resources, and grows first-in-category life sciences companies.

Flagship Pioneering has created over 100 groundbreaking companies over the past twenty years, all of which are pioneering novel and proprietary biological, industrial, and engineering approaches to solve major needs in human health and sustainability. These companies include Moderna (MRNA), Syros Pharmaceuticals (SYRS), Seres Therapeutics (NASDAQ:MCRB), Generate Biomedicines, Tessera Tx, Evelo Biosciences (EVLO), and Indigo Agriculture.

The role

We are seeking an outstanding Research Associate, to join us in building the next generation of Programmable Medicines. We’re looking for a versatile molecular virologist / biochemist with experience in production and characterization of nucleic acids and in molecular cloning. We’re looking for an individual who brings scientific rigor, intellectual curiosity, enthusiasm, and a desire to innovate new nucleic acid therapeutics. This individual will have the opportunity to work in a dynamic and fast-paced entrepreneurial environment, working as part of a highly collaborative and growing team.

Key responsibilities

• Plasmid Production: Design, execute, and troubleshoot molecular cloning of inserts with varying lengths and compositions, ensuring accurate plasmid sequences.
• Inventory Management: Maintain organized storage of produced materials and keep detailed electronic records of material characteristics and storage locations.
• Enzymatic Reaction Optimization: Optimize and troubleshoot enzymatic reactions to enhance nucleic acid production and purity.
• Nucleic Acid Production: Follow and refine protocols to produce high-quality DNA and RNA with diverse expression cassettes.

Who you are

• Technical expert:
• You have 2+ years of industry experience, in immunology or biochemistry, and you’re experienced in nucleic acid and protein innovation, production, purification, and assay development. Or you have a master’s degree and 1+ years of experience in industry and want to be part of a dynamic team.
• Strong experience in independently designing and performing required experiments, as well as interpreting data and sharing results with the team.
• Strong, hands-on experience in cloning through multiple methods (e.g., Gibson, Golden Gate, etc.)
• Solid understanding of enzymatic reactions in nucleic acid synthesis and subsequent modifications.
• Deep understanding of enzymatic reactions involved in nucleic acid synthesis.

• You understand complex scientific concepts and can communicate technical information clearly, concisely, and decisively. Highly organized with strong attention to detail, you excel at systematically arranging and managing information and materials and can create and maintain electronic databases of materials produced, ensuring accessibility to other scientists.
• You flourish in collaborative work environments with other highly skilled individuals. You readily support your colleagues’ challenges and celebrate their victories.

Values and Behaviors:

Flagship is an experiment in institutional, entrepreneurial, and innovation practiced in the context of a small company with an insurgent mindset. We are seeking individuals with an entrepreneurial spirit, strong communication skills, and comfort in working in and contributing to a dynamic and cross-functional team environment.

At Flagship, we recognize there is no perfect candidate. If you have some of the experience listed above but not all, we encourage you to apply anyway. Experience comes in many forms, skills are transferable, and passion goes a long way. We are dedicated to building diverse and inclusive teams and look forward to learning more about your unique background. The level of the role will be commensurate with the education and years of experience of the identified candidates.

Flagship Pioneering and our ecosystem companies are committed to equal employment opportunity regardless of race, color, ancestry, religion, sex, national origin, sexual orientation, age, citizenship, marital status, disability, gender identity or Veteran status.

Recruitment & Staffing Agencies: Flagship Pioneering and its affiliated Flagship Lab companies (collectively, “FSP”) do not accept unsolicited resumes from any source other than candidates. The submission of unsolicited resumes by recruitment or staffing agencies to FSP or its employees is strictly prohibited unless contacted directly by Flagship Pioneering’s internal Talent Acquisition team. Any resume submitted by an agency in the absence of a signed agreement will automatically become the property of FSP, and FSP will not owe any referral or other fees with respect thereto.

The salary range for this role is $65,000 - $93,500. Compensation for the role will depend on a number of factors, including a candidate’s qualifications, skills, competencies, and experience. FL87 currently offers healthcare coverage, annual incentive program, retirement benefits and a broad range of other benefits. Compensation and benefits information is based on FL87's good faith estimate as of the date of publication and may be modified in the future.

The Opportunity

The Senior Director, Trade & Channel Operations will be responsible for building Amylyx’s U.S. distribution and channel model from the ground up in preparation for a future commercial launch of our lead product candidate. This individual will architect the distribution strategy, create the operational infrastructure necessary for launch, and partner cross functionally to ensure Amylyx is fully prepared to commercialize with excellence. As a key member of the Market Access team, this role will influence launch readiness, customer service delivery, and ongoing performance across distribution partners.

Responsibilities

• Design and build Amylyx’s U.S. distribution model across specialty pharmacy, specialty distributor, and 3PL channels to support product launch
• Lead contracting strategy for specialty pharmacies and distributors, including negotiating distribution and service agreements, fee schedules, data requirements, and service levels
• Integrate distribution channels with service programs and field initiatives to enable a seamless customer experience
• Collaborate with Supply Chain and Finance to support 3PL operations, including order‑to‑cash processes, inventory management, data exchange, shipping, returns, and chargeback management
• Establish and manage noncommercial and free‑goods pharmacy operations
• Forecast and model channel performance, assess specialty pharmacy throughput, and provide recommendations to ensure timely, reliable patient access
• Develop distribution analytics including inventory visibility, service metrics, dispense data, time to therapy, and partner scorecards; lead specialty pharmacy QBRs
• Partner cross‑functionally with Supply Chain, Quality, Compliance, Legal, Finance, Patient Services, and Commercial Operations to ensure operational alignment and launch readiness
• Serve as a senior leader within Market Access, contributing to launch planning, forecasting, patient access workflows, and overall distribution strategy
• Continuously optimize post‑launch distribution operations by driving root‑cause remediation, vendor KPI management, and process improvements informed by field and service feedback.

Required Qualifications

• Bachelor’s degree required
• 12+ years of experience in biopharmaceutical trade and distribution, including leadership of specialty pharmacy and distributor channel networks
• Prior product launch experience in the US market
• Experience designing and implementing channel strategies for product launches
• Proven ability to assess, manage, and influence channel partner performance to contractual expectations
• Hands‑on experience with 3PL operations, serialization, state licensing, and compliant distribution processes
• Demonstrated strength in contract negotiation, vendor management, and commercial channel operations
• Deep understanding of payer reimbursement, hub/patient support integration, channel economics, and order‑to‑cash workflows
• Proven leadership experience, including managing large pharmaceutical vendors, with demonstrated people management skills
• Excellent communication, vendor management, analytical, and project execution capabilities

Work Location and Conditions

• At Amylyx, we proudly support remote work opportunities within the United States. However, due to business considerations related to health insurance coverage and state tax regulations, we are unable to hire employees who reside and/or work in certain states. Currently, we are not considering applicants from Alaska, Arizona, Hawaii Michigan and Tennessee.
• You will be expected to travel to our corporate location in Cambridge, MA several times a year and attend other company-related events as necessary and requested.
• You must have access to work in setting which enables meeting all requirements of the role (including privacy, reliable internet access, phone, ability to video conference, etc.) at your remote location.

The Role:

Reporting to the Associate Director, Formulation Sciences, the Senior Manager, Formulation Sciences will act as late-stage drug product subject matter expert and will support drug product process validation toward commercialization. The successful candidate needs to demonstrate a proven record of working in a virtual environment with CDMOs to deliver clinical and commercial supplies in support of fast-paced late-stage development programs. Using strategic thinking, the Senior Manager must be able to develop and execute process validation strategies for successful product commercialization.

This individual has responsibility for support of drug product process validation, scale up, and post-approval changes (SUPAC) and routine commercial manufacturing activities across Nuvalent’s contract research and manufacturing organizations. The primary accountability is being the steward for product development and manufacturing as these programs transition through development and into commercialization. The ultimate goal will be to ensure robust process and manufacture strategies for consistent commercial supply.

Responsibilities:

• Support drug product Process Validation activities, Scale up and post-approval changes (SUPAC) and routine commercial manufacturing at CDMOs.
• Identify critical process parameters based on the risk assessment and understanding the impact of material attributes and process parameters on critical quality attributes. Implement appropriate process controls to ensure delivery of consistent batch product quality.
• Draft, coordinate, execute validation protocols, perform data analysis, author/review and approve process validation reports with consistent and effective communication with other functions.
• Provide support to routine process validation studies, assisting with product technology transfers or lifecycle management changes such as process improvement, addition of secondary API and manufacture site change etc.
• Perform technical review of drug product manufacture deviations, change controls, perform process monitoring (manufacturing data summary and analysis, data presentation), perform activities for drug product lot release (assess deviations and process changes).
• Work closely with other team members and cross-functionally with quality assurance, analytical/QC, chemical development, supply chain, and project management team to achieve all project deliverables.
• Provide support for technical decision-making regarding cGMP compliance, validation strategy and regulatory pathway for SUPAC changes etc.
• Familiar with statistical analysis software, such as JMP.
• Perform process capability analysis, identify risk, and make recommendations for process improvement.
• Manage documentation, change controls, material inventory, product complaints, and deviation resolution at CDMOs.
• Represent the drug product group as a Subject Matter Expert to support audits and regulatory inspections.

• Support authoring the relevant technical sections of regulatory filings.

• Support late-stage validation and post-approval readiness activities and commercial manufacture activities within a virtual working environment.

Competencies:

• Strong organizational, planning, and multitasking skills in a fast‑paced environment.
• Excellent relationship‑building and communication skills across diverse teams.
• Evidence of effective cross‑functional collaboration with both internal teams and external partners.
• Strong problem‑solving and analytical skills with the ability to break down complex issues.
• Results‑driven mindset with attention to quality and timelines. A strong understanding and knowledge of cGMP/ICH regulations and an ability to apply them to drug product development and manufacturing is required.
• Excellent organization and multi-tasking skills.
• Experience building positive and effective cross functional relationships and the ability to align stakeholders, both internally and externally to Nuvalent.

 Qualifications:

• PhD in pharmaceutics, pharmaceutical sciences, chemical engineering or related field with a minimum of 3+ years or MS with 6+ years /BS with 10+ years of industry experience.
• Proven track record on drug product process validation, scale up and manufacture for solid dosage form (tablets).
• Experience with QbD principles and DOE methodology preferred.
• Manage the outsourcing manufacturing activities at CDMO sites to meet CMC goals.
• Understanding of cGMP/ICH guidelines and the ability to apply them to development and manufacturing.

• Experience with solid dosage form (tablet) process development; exposure to late-stage validation is a plus.

• Ability to author and critically review relevant development reports as well as regulatory dossiers.
• Up to 25% travel is expected, both domestically and internationally.

Additional Information:

Nuvalent is committed to fair and equitable compensation practices, aiming to provide employees with competitive total rewards packages.

The targeted salary range reflects what Nuvalent reasonably and in good faith expects to offer for this position at the time of posting, but the final salary determination may be within or outside this range based on various factors, including, but not limited to, experience, skills, education, and market factors.  The range will be reviewed regularly and is subject to change.

Nuvalent also offers a comprehensive benefit package to support our employees at each stage of their career, financial, health, and well-being journey, including medical, dental, and vision insurance, 401(k) retirement savings plan, generous paid time off (including a summer and winter company shutdown), and much more.

*This job listing is open indefinitely, so if we are not currently hiring at a studio location near you, we will be sure to keep your information on file and reach out when an opportunity arises.*

Want to get paid to become a piercer at Studs? Apprentices undergo a minimum 6-week paid piercing training program inclusive of classroom style learning, observation, and hands-on training. We are always looking for Apprentices to join our training program! Upon successful completion of the program, graduated Apprentices will become eligible for a Part Time or Full Time Associate Piercer position at one of our studio locations.

Hourly Rate:

• Graduated apprentices make $24/hour as Associate Piercers, plus tips
  During the 6-week training program, apprentices make $18/hour, plus tips

Key Responsibilities:

REVENUE 

Service Oriented 

• Embodies our performance-oriented culture by meeting and exceeding expectations 
• Serves as a brand ambassador: educates clients on the unique Studs’ experience through our selling cycle 
• Delivers confident, clear, and professional communication with clients during their entire Studs’ experience 

OPERATIONS 

Decision Quality & Execution 

• Leverages Studs’ resources and policies in decision making  
• Becomes well-versed in piercing operating procedures and regulations to ensure client experience and work safety standards are met 
• Shows consistent and detailed record keeping of all maintenance, sterilized inventory and tools

TALENT 

Integrity

• Prioritizes Studio compliance and is accountable to standard operating procedures and company policy 
• Admits mistakes and is not afraid to escalate when help is needed 
• Lives out our Core Values 
• Shows consistency by providing best in class service to everyone in the Studio 
• Provides solutions-oriented feedback and is open-minded to receiving it 

Requirements:

• 3 years of relevant work experience
• At least two years as a Medical Assistant or Phlebotomist (performing venipunctures and/or finger sticks) preferred
• Full Time:
  • Must be available to work a flexible schedule up to 5 days per week (32+ hours), including evenings, weekends, and holidays. Must maintain consistent availability
  • Weekend availability (Friday, Saturday, Sunday) is required, excluding approved PTO
  • Schedules may vary based on business needs, and Full-Time employees are expected to prioritize Studs as their primary employment commitment
• Part Time:
  • Must be available to work a flexible schedule of varying days and hours, including evenings, weekends, and holidays
  • Must have availability to work on Saturday and Sunday, excluding approved unscheduled time away
  • Reliably attend work as scheduled for up to 29 hours per week, in line with local laws and subject to any approved accommodations
• Must pierce a minimum 18 appointments a day
• Must be able to visually inspect ear anatomy to execute advanced piercings
• Must be able to deliver piercings with a steady hand
• Must be able to lift 20 lbs
• Must be able to handle chemicals safely
• Travel to one of our studio locations for the duration of the training program (paid by Studs)
• Driven, creative problem solver that consistently acts with integrity and speaks up
• Owner’s mindset, with the ability to approach feedback and problems with a positive attitude.

Benefits & Perks:

Full Time:

• Comprehensive Medical, Dental, and Vision Insurance (including $0 in-network mental health visits)
• Access to Mental Health and Work/Life Resources  including Online Therapy, Gender Affirmation Support Services, and Employee Assistance Program (EAP)
• Voluntary Life Insurance
• Health and Commuter Tax-Advantaged Accounts
• 401(k) Retirement Savings Plan
• Paid Time Off and Paid Safe & Sick Leave Accruals
• Paid Parental Leave
• Paid Sabbatical After 4 Years of Service
• Exclusive Employee Discounts on Piercings and Jewelry (we’ve got your friends and family covered too!)
• Access to PerkSpot and additional benefits such as pet insurance, discounted tickets, personal finance coaching, healthy rewards, and more!

Part Time:

• Paid Safe & Sick Leave Accrual
• FSA Health and Commuter Tax-Advantaged Accounts
• 401(k) Retirement Savings Plan
• Exclusive Employee Discounts on Piercings and Jewelry (we’ve got your friends and family covered too!)

An opportunity has arisen for a Supply Chain Operator within our Cambridge based Operations team. This role is responsible for delivering all aspects of an efficient end-to-end supply chain within Operations, including kit assembly, goods in/out, warehousing customer service and inventory management, whilst providing additional support to projects and continuous improvement initiatives.

What you’ll be doing for us

To work as part of a team in executing tasks as directed by the Finished Goods Supervisor including, but not limited to, the following activities:  

• Final product assembly
• Maintain Dangerous Goods and Dry Ice certification
• Print and reconcile version-controlled documents and labels confidently and independently
• Monitor and maintain tock levels of materials and reagents within the kit assembly area, identify and raise order requisitions and/or material requests for replenishment
• Oversee and ensure the maintenance of cleanliness and organisation of the kit assembly and dispatch areas, bench areas and fridge/ freezers
• Raise Material Transfer Form requests to replace stock as necessary
• Assist with Materials Management tasks as directed, including the selection, and picking of warehouse items using the MRP system
• Assist, when required, with creating packing sheets, adding stock entries and keying orders into the SAGE accounting system
• Provide support across various Supply Chain functions including kit packing, dispatch, goods in processing and general warehouse operations
• Liaise with Customer Services to ensure customer orders are fulfilled, prepared and dispatched on time
• Execute and document tasks using approved ISO compliant documentation
• Adhere to procedures documented in the Cytocell quality system and ensuring that any non-compliance noted is reported in a timely manner using approved procedures
• Ensuring safety related issues are reported, including completion of relevant documentation
• Write and update SOP’s BMR’s and other documentation as required
• Working within the dispatch area, liaising within Customer Services to ensure customer orders are fulfilled, prepared and dispatched on time
• Pro-actively seek out and identify opportunities for process improvements and make recommendations to Supervisory Team
• Collaborate with internal and external partners to drive the sustainable agenda along the entire supply chain
• Collaborate with cross-functional scientific, laboratory and R&D teams that include a diverse range of personalities and skills.

To provide support to other areas of operation as required:

• Complete tasks as commensurate with the level and nature of the post as delegated by the Finished Goods Supervisor
• Assist when required with warehouse goods-in and material transfer processes and update inventory systems accordingly
• Maintain accurate inventory records and ensure warehouse inventory levels are optimized to meet manufacturing demand while minimizing carrying costs
• Identify and investigate any inventory discrepancies or issues and implement corrective actions.

What we are looking for in you

Essential

• Knowledge and experience of working within ISO and GMP environments
• Growth mindset – actively searching out opportunities for improvement, simplification and reduction in waste
• Right first time - strong attention to detail and excellent organisational skills
• Effective written and verbal communication abilities
• Ability to work collaboratively in a team
• Ability to prioritize tasks and work well in a fast-paced environment
• Computer literacy
• Ability to be in the office 5 days per week.

Desirable

• Knowledge and experience of customer service, ERP export, dispatch and production processes
• Knowledge of requirements of ISO9001 & ISO13485.

In return you’ll receive:

• Competitive salary
• Pension Scheme (10% non-contributory)
• Private Health Insurance
• Private Dental Insurance
• Group Income Protection
• Group Life Assurance
• 25 days holiday plus UK bank holidays
• High Street Discount Scheme.