About Alltrna 

Alltrna is the first clinical-stage biotech company advancing tRNA medicines to address shared disease-causing mutations across many indications. The company’s initial therapeutic programs are designed to restore full-length protein production in diseases caused by premature termination codons (PTCs), collectively referred to as Stop Codon Disease, which affect approximately 10% of people with a rare genetic disease.

Alltrna’s lead program, AP003, is a chemically modified, engineered tRNA oligonucleotide encapsulated in a clinically validated, liver-directed lipid nanoparticle. AP003 is being developed for the arginine-to-TGA (Arg-TGA) PTC in patients with liver Stop Codon Disease, including phenylketonuria, organic acidemias, and urea cycle disorders. Founded in 2018 by Flagship Pioneering, Alltrna has built an integrated platform to design, optimize, and deliver engineered tRNA therapeutics. 

For more information, visit www.alltrna.com

Sr. Director Program Management & Business Operations

Position Summary:

Alltrna is seeking a talented and highly motivated Sr. Director Program Management and Business Operations, reporting to the President & CFO.  The successful candidate is a proven leader with extensive experience in leading research and early drug development program teams from research through the clinic with a particular initial focus on IND enabling and early/mid-stage clinical development. The candidate will be a member of the Company’s Leadership Team and will serve as Chief of Staff to the team to drive collaboration, cross-functional clarity, alignment and execution on key priorities and initiatives required to meet the goals of the organization.

Key Responsibilities:

Program Management:

• Work closely with the Chief Medical Officer to lead the program team for the Company’s lead program, AP003, and future programs instilling a culture of scientific rigor, open debate, collaborative teamwork, sense of urgency and accountability
• Possess a comprehensive understanding of the drug discovery process to guide program teams to define the key scientific questions, program strategy and objectives, translating these into optimal deliverables, cross-functional plans, timelines and budgets
• Identify bottlenecks, risks, issues and proactively develop appropriate mitigation proposals with input from team members
• Ensure all key decisions are identified and properly assessed as to their impact and alternative scenarios developed and evaluated, where appropriate
• Work closely with finance and functional teams to develop the operational plans to support program activities with realistic timelines, budget, and resource planning and monitor performance against plans
• Interface with and drive collaboration between the various functional teams and with the Leadership Team on program-related matters.
• Be the key accountable person for communicating matters related to the programs to management including strategy, work product, updates and issues; producing the one “source of truth” for program-related topics and timelines
• Point person for alliance management and coordination, as needed
• Lead and/or manage strategic or platform development projects as required and collaborate with Chief Scientific Officer and Research Leadership Team to coordinate relevant content for quarterly business review meetings

Operations:

• Collaborate with Leadership Team in development of strategic plans, company goals, long-range planning assumptions, portfolio-level reports and analyses to support business processes and strategic discussions
• Develop and deliver impactful presentations that effectively distill complex issues to the critical points and lead to increased understanding and optimized strategic planning & decision-making

• Prepare strategic communications utilizing a clear understanding of the business strategy and issues; develop and maintain consistent, relevant content for use in executive-level communications and to further organizational and business goals

• Lead the Scientific Communications process, working with the Scientific Communications Committee

• Manage schedule, agenda, and content for Leadership Team, Board of Directors and Town Hall meetings

• Proactively seek opportunities for organizational improvements (e.g. team structure, processes, communication, etc.)

Other:

• Support CEO / LT with partnership discussions and negotiations, including background research, preparation of presentation materials, supporting diligence activities, participating in analysis of terms, etc.
• Assist in mapping competitive landscape and proactively identify potential and emerging competitive threats and opportunities
• Promote strategic discussions on external trends, competitor strategies, and potential disruptors, and translate these into strategic choices/ recommendations
• Collect insights and intelligence from a variety of sources including literature searches, reviewing analyst research, KOL and patient group interactions, etc.

Key Competencies:

• This is a highly visible leadership role that requires exceptional interpersonal and communication skills, creative thinking, and early drug development experience that allows one to recognize opportunities/challenges and modify strategy accordingly
• The individual will need to have self-confidence and poise to manage complicated programs and projects with multiple stakeholders

• The individual will need a sense of urgency and can-do attitude to develop therapies for patients with significant unmet medical needs

Minimum Qualifications:

• BS/MS Degree in a scientific discipline, ideally life science or chemistry.
• At least 15 years relevant experience in pharma or biotech drug discovery and development, as well as a comprehensive understanding of drug discovery (preclinical and clinical).
• 10+ years of Program Management experience, preferably in early-stage drug discovery and development.
• Experience in the development of advanced therapies to treat rare genetic disease is a plus
• Demonstrated experience leading cross-functional teams; strong interpersonal and communication skills
• Scientific curiosity and passion for discovering new, innovative medicines.
• Openness to embrace new technologies and digital approaches in drug discovery
• Proven track record in driving successful, collaborative drug discovery teams.

The salary range for this role is $213,000 - $280,500. Compensation for the role will depend on a number of factors, including a candidate’s qualifications, skills, competencies, and experience. Alltrna currently offers healthcare coverage, annual incentive program, retirement benefits and a broad range of other benefits. Compensation and benefits information is based on Alltrna's good faith estimate as of the date of publication and may be modified in the future.

About Alltrna 

Alltrna is the first clinical-stage biotech company advancing tRNA medicines to address shared disease-causing mutations across many indications. The company’s initial therapeutic programs are designed to restore full-length protein production in diseases caused by premature termination codons (PTCs), collectively referred to as Stop Codon Disease, which affect approximately 10% of people with a rare genetic disease.

Alltrna’s lead program, AP003, is a chemically modified, engineered tRNA oligonucleotide encapsulated in a clinically validated, liver-directed lipid nanoparticle. AP003 is being developed for the arginine-to-TGA (Arg-TGA) PTC in patients with liver Stop Codon Disease, including phenylketonuria, organic acidemias, and urea cycle disorders. Founded in 2018 by Flagship Pioneering, Alltrna has built an integrated platform to design, optimize, and deliver engineered tRNA therapeutics. 

For more information, visit www.alltrna.com

Sr. Director Program Management & Business Operations

Position Summary:

Alltrna is seeking a talented and highly motivated Sr. Director Program Management and Business Operations, reporting to the President & CFO.  The successful candidate is a proven leader with extensive experience in leading research and early drug development program teams from research through the clinic with a particular initial focus on IND enabling and early/mid-stage clinical development. The candidate will be a member of the Company’s Leadership Team and will serve as Chief of Staff to the team to drive collaboration, cross-functional clarity, alignment and execution on key priorities and initiatives required to meet the goals of the organization.

Key Responsibilities:

Program Management:

• Work closely with the Chief Medical Officer to lead the program team for the Company’s lead program, AP003, and future programs instilling a culture of scientific rigor, open debate, collaborative teamwork, sense of urgency and accountability
• Possess a comprehensive understanding of the drug discovery process to guide program teams to define the key scientific questions, program strategy and objectives, translating these into optimal deliverables, cross-functional plans, timelines and budgets
• Identify bottlenecks, risks, issues and proactively develop appropriate mitigation proposals with input from team members
• Ensure all key decisions are identified and properly assessed as to their impact and alternative scenarios developed and evaluated, where appropriate
• Work closely with finance and functional teams to develop the operational plans to support program activities with realistic timelines, budget, and resource planning and monitor performance against plans
• Interface with and drive collaboration between the various functional teams and with the Leadership Team on program-related matters.
• Be the key accountable person for communicating matters related to the programs to management including strategy, work product, updates and issues; producing the one “source of truth” for program-related topics and timelines
• Point person for alliance management and coordination, as needed
• Lead and/or manage strategic or platform development projects as required and collaborate with Chief Scientific Officer and Research Leadership Team to coordinate relevant content for quarterly business review meetings

Operations:

• Collaborate with Leadership Team in development of strategic plans, company goals, long-range planning assumptions, portfolio-level reports and analyses to support business processes and strategic discussions
• Develop and deliver impactful presentations that effectively distill complex issues to the critical points and lead to increased understanding and optimized strategic planning & decision-making

• Prepare strategic communications utilizing a clear understanding of the business strategy and issues; develop and maintain consistent, relevant content for use in executive-level communications and to further organizational and business goals

• Lead the Scientific Communications process, working with the Scientific Communications Committee

• Manage schedule, agenda, and content for Leadership Team, Board of Directors and Town Hall meetings

• Proactively seek opportunities for organizational improvements (e.g. team structure, processes, communication, etc.)

Other:

• Support CEO / LT with partnership discussions and negotiations, including background research, preparation of presentation materials, supporting diligence activities, participating in analysis of terms, etc.
• Assist in mapping competitive landscape and proactively identify potential and emerging competitive threats and opportunities
• Promote strategic discussions on external trends, competitor strategies, and potential disruptors, and translate these into strategic choices/ recommendations
• Collect insights and intelligence from a variety of sources including literature searches, reviewing analyst research, KOL and patient group interactions, etc.

Key Competencies:

• This is a highly visible leadership role that requires exceptional interpersonal and communication skills, creative thinking, and early drug development experience that allows one to recognize opportunities/challenges and modify strategy accordingly
• The individual will need to have self-confidence and poise to manage complicated programs and projects with multiple stakeholders

• The individual will need a sense of urgency and can-do attitude to develop therapies for patients with significant unmet medical needs

Minimum Qualifications:

• BS/MS Degree in a scientific discipline, ideally life science or chemistry.
• At least 15 years relevant experience in pharma or biotech drug discovery and development, as well as a comprehensive understanding of drug discovery (preclinical and clinical).
• 10+ years of Program Management experience, preferably in early-stage drug discovery and development.
• Experience in the development of advanced therapies to treat rare genetic disease is a plus
• Demonstrated experience leading cross-functional teams; strong interpersonal and communication skills
• Scientific curiosity and passion for discovering new, innovative medicines.
• Openness to embrace new technologies and digital approaches in drug discovery
• Proven track record in driving successful, collaborative drug discovery teams.

The salary range for this role is $213,000 - $280,500. Compensation for the role will depend on a number of factors, including a candidate’s qualifications, skills, competencies, and experience. Alltrna currently offers healthcare coverage, annual incentive program, retirement benefits and a broad range of other benefits. Compensation and benefits information is based on Alltrna's good faith estimate as of the date of publication and may be modified in the future.

We are seeking a Deputy Chief Engineer to lead our efforts in developing and deploying capabilities for artificial intelligence, machine learning, data management, decision systems, and mission planning software applications for the US National Security Ecosystem. This is an exceptional opportunity for an engineer with a combination of technical expertise, program leadership experience, and the ability to interface with customers to drive innovation, collaboration, and excellence in a fast-paced, growing organization.

Responsibilities:

• Set the technical vision and direction for programs, collaborating with internal technical staff and external customers

• Lead multidisciplinary teams developing algorithms, software, cloud, and data management solutions

• Manage program execution, ensuring schedule and budget adherence, and overseeing successful program delivery

• Cultivate strong relationships with external partners and stakeholders, advocating for MORSE's technology and services

• Identify and pursue new business opportunities, expanding our portfolio and driving long-term growth

• Provide technical oversight and guidance to program team members

Requirements:

• US Citizenship and ability to obtain and maintain a Security Clearance

• Bachelor’s or Master’s or PhD in Computer Science, Software Engineering, Aerospace Engineering, Electrical Engineering, Physics or a related field

• Minimum of 5 years of experience in software development, with a focus on AI/ML, cloud computing, and/or decision systems

• Proven leadership skills, with a track record of successfully managing high-performing technical teams

• Deep understanding of software development principles, methods, and tools

• Strong analytical and problem-solving abilities, with the capacity to absorb complex technical information quickly

• Excellent written and verbal communication skills, with the ability to present technical information clearly and persuasively to both technical and non-technical audiences

• Experience with Agile methodologies and DevOps practices

• Familiarity with cloud computing platforms and infrastructure is nice to have 

We are seeking a Deputy Chief Engineer to lead our efforts in developing and deploying capabilities for artificial intelligence, machine learning, data management, decision systems, and mission planning software applications for the US National Security Ecosystem. This is an exceptional opportunity for an engineer with a combination of technical expertise, program leadership experience, and the ability to interface with customers to drive innovation, collaboration, and excellence in a fast-paced, growing organization.

Responsibilities:

• Set the technical vision and direction for programs, collaborating with internal technical staff and external customers

• Lead multidisciplinary teams developing algorithms, software, cloud, and data management solutions

• Manage program execution, ensuring schedule and budget adherence, and overseeing successful program delivery

• Cultivate strong relationships with external partners and stakeholders, advocating for MORSE's technology and services

• Identify and pursue new business opportunities, expanding our portfolio and driving long-term growth

• Provide technical oversight and guidance to program team members

Requirements:

• US Citizenship and ability to obtain and maintain a Security Clearance

• Bachelor’s or Master’s or PhD in Computer Science, Software Engineering, Aerospace Engineering, Electrical Engineering, Physics or a related field

• Minimum of 5 years of experience in software development, with a focus on AI/ML, cloud computing, and/or decision systems

• Proven leadership skills, with a track record of successfully managing high-performing technical teams

• Deep understanding of software development principles, methods, and tools

• Strong analytical and problem-solving abilities, with the capacity to absorb complex technical information quickly

• Excellent written and verbal communication skills, with the ability to present technical information clearly and persuasively to both technical and non-technical audiences

• Experience with Agile methodologies and DevOps practices

• Familiarity with cloud computing platforms and infrastructure is nice to have 

We are seeking a Deputy Chief Engineer to lead our efforts in developing and deploying capabilities for artificial intelligence, machine learning, data management, decision systems, and mission planning software applications for the US National Security Ecosystem. This is an exceptional opportunity for an engineer with a combination of technical expertise, program leadership experience, and the ability to interface with customers to drive innovation, collaboration, and excellence in a fast-paced, growing organization.

Responsibilities:

• Set the technical vision and direction for programs, collaborating with internal technical staff and external customers

• Lead multidisciplinary teams developing algorithms, software, cloud, and data management solutions

• Manage program execution, ensuring schedule and budget adherence, and overseeing successful program delivery

• Cultivate strong relationships with external partners and stakeholders, advocating for MORSE's technology and services

• Identify and pursue new business opportunities, expanding our portfolio and driving long-term growth

• Provide technical oversight and guidance to program team members

Requirements:

• US Citizenship and ability to obtain and maintain a Security Clearance

• Bachelor’s or Master’s or PhD in Computer Science, Software Engineering, Aerospace Engineering, Electrical Engineering, Physics or a related field

• Minimum of 5 years of experience in software development, with a focus on AI/ML, cloud computing, and/or decision systems

• Proven leadership skills, with a track record of successfully managing high-performing technical teams

• Deep understanding of software development principles, methods, and tools

• Strong analytical and problem-solving abilities, with the capacity to absorb complex technical information quickly

• Excellent written and verbal communication skills, with the ability to present technical information clearly and persuasively to both technical and non-technical audiences

• Experience with Agile methodologies and DevOps practices

• Familiarity with cloud computing platforms and infrastructure is nice to have 

Job Summary:

We are seeking an experienced and talented Chief Engineer to lead our efforts in developing and deploying capabilities for artificial intelligence, machine learning, decision systems, and mission planning applications. This is an exceptional opportunity for a seasoned engineer to drive innovation, collaboration, and excellence in a fast-paced and growing organization.

Responsibilities:

• Set the technical vision and direction for programs, collaborating with internal technical staff and external customers

• Lead multi-disciplinary teams developing algorithmic, software, cloud, and data solutions

• Manage program execution, ensuring schedule and budget adherence, and overseeing successful program delivery

• Cultivate strong relationships with external partners and stakeholders, advocating for MORSE's technology and services

• Identify and pursue new business opportunities, expanding our portfolio and driving long-term growth

• Provide technical oversight and guidance to program team members

Requirements:

• US Citizenship and ability to obtain and maintain a Security Clearance. Active Secret, Top Secret, or TS/SCI is preferred. 

• Master's degree or PhD in Aerospace Engineering, Computer Science, Physics, Electrical Engineering, or a related field

• Minimum of 10 years of experience in R&D, with a focus on AI/ML, software, and decision systems

• Proven leadership skills, with a track record of successfully managing high-performing technical teams

• Deep understanding of software development principles, methods, and tools

• Strong analytical and problem-solving abilities, with the capacity to absorb complex technical information quickly

• Excellent written and verbal communication skills, with the ability to present technical information clearly and persuasively to both technical and non-technical audiences

• Experience with Agile methodologies and DevOps practices

• Familiarity with cloud computing platforms and infrastructure is nice to have

MORSE is seeking an experienced and talented Chief Engineer to lead our efforts in developing and deploying capabilities for artificial intelligence, machine learning, decision systems, and mission planning applications. This is an exceptional opportunity for a seasoned engineer to drive innovation, collaboration, and excellence in a fast-paced and growing organization.

Responsibilities:

• Set the technical vision and direction for programs, collaborating with internal technical staff and external customers

• Lead multi-disciplinary teams developing algorithmic, software, cloud, and data solutions

• Manage program execution, ensuring schedule and budget adherence, and overseeing successful program delivery

• Cultivate strong relationships with external partners and stakeholders, advocating for MORSE's technology and services

• Identify and pursue new business opportunities, expanding our portfolio and driving long-term growth

• Provide technical oversight and guidance to program team members

Requirements:

• US Citizenship and ability to obtain and maintain a Security Clearance. Active Secret, Top Secret, or TS/SCI is preferred. 

• Master's degree or PhD in Aerospace Engineering, Computer Science, Physics, Electrical Engineering, or a related field

• Minimum of 10 years of experience in R&D, with a focus on AI/ML, software, and decision systems

• Proven leadership skills, with a track record of successfully managing high-performing technical teams

• Deep understanding of software development principles, methods, and tools

• Strong analytical and problem-solving abilities, with the capacity to absorb complex technical information quickly

• Excellent written and verbal communication skills, with the ability to present technical information clearly and persuasively to both technical and non-technical audiences

• Experience with Agile methodologies and DevOps practices

• Familiarity with cloud computing platforms and infrastructure is nice to have

Director, Finance & Administration

Harvard Hillel

Location: On Site, Harvard Hillel  |  Cambridge, MA

Employment Status: Exempt salaried staff member

Reporting: Jason Rubenstein, Executive Director 

Salary Range: $100,000 - $120,000

Role Overview

The mission of Harvard Hillel is to be a Jewish home, both physical and virtual, on the Harvard University campus. Harvard Hillel welcomes all students to experience the variety of Jewish identity, tradition, practice, values, culture, and community and to inspire and enable connections on campus and beyond. Harvard Hillel students find meaningful connections and friendship while engaging in unique opportunities to make Jewish thought and culture integral in the life of the University.

The Director, Finance & Administration (Director) reports to the Harvard Hillel executive director who has been in the role less than two years. As a team, you will engage effectively with internal and external constituent groups around operational excellence at Harvard Hillel. The Director will move easily between strategic decision-making, governance requirements, and the everyday tactical coordination and planning that brings operational priorities to fruition. The Director serves as an empathetic and collaborative leader and coach, where operational excellence and a positive engagement around organizational culture is as important as rigorous monitoring of systems and process.

The Director’s role will ensure effective and consistent financial integrity and compliance of this 501(c)(3) institution. Working closely with the executive director, chief of staff, and other stakeholders, the Director will oversee the planning, coordination, and tracking of institutional annual goals against budget. The Director will serve as a trusted advisor and thought partner to the executive director and staff on organizational priorities, strategic goal setting, and effective project coordination in relation to designing and meeting budget goals.

Key to the success of the Director’s role is to add capacity to the executive director to support the transformation of the institution and its future. In year one, the Director will actively engage with colleagues and outsourced providers to modernize financial budgeting systems, tracking and reporting. Over time, a successful Director in this role will help reshape Harvard Hillel—its building and its operations, to move the organization forward.

Anticipated accountabilities are outlined below. The Director will be expected to actively surface and collaboratively projects to design and address anomalies to ensure work moves forward effectively and efficiently.

What You’ll Do

Annual Planning & Financial Management

• Accounting, Banking, Benefits, Insurances, Payroll: accountability for ensuring an annual cycle, with relevant systems, tracking, and reporting designed and implemented to record and reflect on the overall fiscal health of the organization.
  • Lead annual budget cycle: engaging with budget holders and other colleagues to establish and coordinate an effective budget planning process and reporting tools to support budget holders’ ability to manage and track their budgets and cashflow. At minimum, monthly and quarterly budget reviews, cash flow management and reporting, and ad-hoc tracking and issue resolution as needed. Ensure organizational priorities are visible, clear, and actionable in relation to budget monitoring and tracking. Lead communications in relation to annual budget cycle process and the obligations of contributors. Serve as a trusted colleague and coach around budget management, accountability, and tracking in relation to finance and budgets.
  • Lead annual cycle of audited financial statements and filings: engage with external providers to oversee and actively manage the timely scheduling and delivery of an annual audit; delivery of a 990, and to meet an annual schedule of filing obligations.
  • Annual Insurances: engage with a broker and others to manage insurance obligations for this 501(c)(3) organization.
  • Departmental planning and analyses: In year one, redesign financial planning, budgeting, tracking, and reporting systems, with analysis tools that are right-sized for the institution, in preparation for a capital project to renovate the historic Rosovsky building and to support the institution's journey to scale.

Board of Directors Operations

• Working closely with the chief of staff and executive director, and Board committees, plan and coordinate audit, finance, and risk related committees and reporting to meet timely Board reporting and meetings. Serve as the staff liaison for finance, audit, and risk related committee meetings and discussions.
• Support committee development, structures, and governance principles and processes to ensure the organization’s ByLaws support and drive compliance and governance decision-making in relation to financial risk.

Fiscal Sponsorships Management

• In close coordination with the Director of Programs and others, actively manage student-led initiatives related to financial controls, guidance on policy, procurement, and expenditures and timely payments of events for student-led projects.

Policy Design and Management

• Actively review and manage organizational policies in relation to both risk management and business continuity, balancing the organization’s values and core programming, to facilitate a smooth-running institution in service of students and other stakeholders.
• Schedule routine policy review cycles to ensure the organization is up to date with best practices and technologies to function with operational excellence.

Human Resources

• Work closely with payroll providers and benefits brokers to manage an annual benefits cycle of enrollments and benefits assessments, actively engaging and communicating with staff through a benefits review cycle.
• Actively engage with the chief of staff to design and implement an annual cycle of health and safety protocols specific to this institution. Working closely with the chief of staff and executive director, actively track and monitor engagement in mandatory trainings for Boston, MA.
• Work in close partnership as needed on staff disciplinary activities, including investigations, performance management support, hiring and termination, holding personnel records and record keeping for related human resources materials.

Facilities

• Oversee the planning of budgets and coordination support needs for buildings owned or rented by Harvard Hillel.
• Oversee the health and safety, security, and business continuity planning around onsite activities, in close partnership with the manager of facilities and operations and the executive director.
• Oversee onsite programmatic activities and events in close liaison with the Director of Program and Facilities Manager, ensuring smooth running of event scheduling, planning, and logistics.
• Oversee management and coordination of facilities technologies serve onsite programming through facilities.
• Identify and manage cost-savings opportunities for services provided by Harvard University and others.

Minimum Qualifications

• 10+ years of experience as a CFO with an Operations portfolio, Finance & Operations Manager, or similar role in a nonprofit or community engagement organization.
• High comfort in Microsoft Office tools, QBO, Bill.com, other financial management platforms.
• Bachelor’s Degree or equivalent.

Knowledge, Skills and Abilities 

• 8+ years of progressive experience in nonprofit or mission-driven leadership roles.
• Commitment to the organization’s mission and respectful of Jewish values.
• Demonstrated success in strategic planning and execution, operational systems and tracking, and Board governance. People-center systems thinker, with strong success operationalizing strategies into trackable, measurable action plans.
• Strong financial, project management, and institutional administration skills.
• Exceptional written, verbal, and interpersonal skills.
• Highly effective manager of people, projects, and budgets.
• Adaptable, sound judgment, diplomatic, and respectful of holding sensitive information.
• Ability to successfully balance high emotional intelligence with result-driven project management and serving as an empathetic culture carrier who models collaborative leadership and teamwork.
• Open and willing to engage in conversations about religion, and to learn about Judaism and Israel in a way that inspires stakeholders to invest in our work.
• Highly collaborative problem-solver with curiosity to engage across teams both inside and outside of Hillel to successfully manage competing priorities.
• A self-starter, adept at project management tools and practices, time-management and effective communications both verbally and in writing.
• Highly comfort working effectively both independently and in teams to meet goals and deadlines.

Benefits

• A comprehensive benefits package, including health insurance, retirement plan, Life, AD&D and Long-Term Disability (LTD) insurances, Flexible Spending accounts, generous vacation/sick time, and parental leave.
• A unique opportunity to develop and promote a vibrant, pluralistic Jewish community at Harvard Hillel.

Harvard Hillel is affiliated with Hillel International. Hillel International enriches the lives of Jewish students so they may enrich the Jewish people and the world, and envisions a world where every student is inspired to make an enduring commitment to Jewish life, learning and Israel.

About the Role

The Chief of Staff (CoS) will work closely with the CEO, serving as a trusted advisor, gatekeeper, problem solver and strategic partner to develop and implement strategies that advance our mission. It is a fast-track role to become an Executive in the company, and you will be a member of the Executive Team. In this role you will have both internal and external-facing responsibilities, and will provide strategic oversight to operational and communication needs across the company. 

As the CoS, you will have to handle complex situations and multiple responsibilities simultaneously, mixing long term projects with the urgency of immediate demands. This role is a front seat to all the action in getting a startup off the ground and a terrific opportunity to leverage your broad visibility into the organization to identify challenges, develop solutions, and be an integral part of executing critical workflows. This is an ideal role for a top-performer who thrives at the intersection of strategy and execution, enjoys solving ambiguous problems, and wants accelerated exposure to executive-level decision making. 

This role is part of the Office of the CEO and will directly manage the current Strategy and Operations team. You'll be onboarding with the current Chief of Staff, and reporting to our CEO once ramped.

Responsibilities

Strategic Partnership to the CEO

• Serve as a trusted advisor and strategic thought partner, helping the CEO prioritize, sequence, and drive the company’s most critical decisions
• Act as an extension of the CEO’s capacity - amplifying insight, synthesizing information, and ensuring the CEO’s time is leveraged for the highest-impact activities
• Prepare executive communications, board narratives, leadership offsites, and strategic briefings.

Organizational Alignment & Operating Rhythm

• Own the company’s operating cadence, including Executive Team meetings, quarterly planning, reviews, and cross-functional forums
• Ensure organizational alignment on priorities, metrics, and accountability frameworks
• Drive clarity across teams by translating strategic goals into executable plans

Decision Support & Insight Generation

• Structure analyses that distill complex data into actionable insights for the CEO and leadership team.
• Provide decision support for strategic opportunities, including market assessments, product expansion initiatives, partnership evaluation, or financial modelingIncrease the quality and speed of decision-making across the company through high-quality strategic research

Execution Leadership for Strategy and Operations function

• Lead and project manage multi-threaded, high-stakes company initiatives that span clinical operations, site network growth, product development, commercial strategy, and people operations.
• Build frameworks, workflows, and playbooks that improve organizational performance and scale
• Lead and manage the Strategy and Operations team (currently 1 direct report)

Internal and External Communications

• Support CEO communication with employees, the Board, investors, partners, and key customersEnsure information flows seamlessly across teams and that the CEO is prepared for all engagements
  
  

What We’re Looking For

Required Qualifications

• 6-8 years of experience in management consulting, strategy, business operations, or a comparable high-performance environment.
• Strong business acumen with familiarity in healthcare, life sciences, digital health, or tech-enabled services
• Proven ability to structure problems, build analytical frameworks, and generate concise, insight-rich recommendations
• Exceptional project management skills: ability to run multiple initiatives, align stakeholders, and drive outcomes independently
• Strong executive presence with the ability to earn trust quickly and communicate with clarity and influence
• Experience thriving in fast-paced, high-growth, ambiguous environments
• Willingness to be in our NYC or Cambridge office 2+ days per week
• Willingness to travel ~15% for customer, partner, or conference engagement

Preferred Qualifications

• Experience in health-tech, clinical research, or AI-driven healthcare solutions
• Exposure to C-suite advising, board engagement, or executive-level decision support
• Prior experience working inside a scaling startup or operator role