About the Team 

The DMP team plays a critical role in Roku’s Advertising organization, leading initiatives around audience management that power decision-making across the advertising ecosystem. We develop and manage products that enable advanced segmentation and audience management for advertisers while meeting the operational needs of internal teams. 

We work closely with Product Managers, Machine Learning, Ad Sales, Ads Operations, and multiple groups within Advertising Engineering to deliver high-impact solutions.  

Looking ahead, we are exploring AI-driven capabilities to further enhance the effectiveness of advertising campaigns and improve operational efficiency of our platforms. 

About the Role 

We are seeking a highly skilled Senior Software Engineer with deep expertise in big data technologies, including Apache Spark and Apache Airflow. This hybrid position bridges software engineering and data engineering, requiring the ability to design, build, and maintain scalable systems for both application development and large-scale data processing. 

In this role, you will collaborate with cross-functional teams to architect and manage robust, production-grade data products and APIs that power critical capabilities across the advertising platform. You will work with technologies such as Apache Spark, Apache Airflow, ScyllaDB/Cassandra, Aerospike, Kubernetes, and SpringBoot to deliver reliable, high-performance solutions. 

The ideal candidate is a proactive, self-motivated professional with a strong track record in building high-scale data services and a dedication to delivering exceptional results. 

What You’ll Be Doing 

Software Development 

• Design and build APIs and backend services using Spring Boot to support data products and audience management workflows. 

• Write clean, maintainable, and efficient code, ensuring adherence to best practices through code reviews. 

Big Data Engineering 

• Design, develop, and maintain data pipelines and ETL workflows using Apache Spark and Apache Airflow. 

• Optimize data storage, retrieval, and processing systems to ensure reliability, scalability, and performance. 

• Develop and fine-tune complex queries using Apache Spark for large-scale datasets. 

• Monitor, troubleshoot, and improve data systems to minimize downtime and maximize efficiency. 

API and Platform Development

• Design, Development, and maintain large scale, low latency API systems using SpringBoot and Kubernetes

• Maintain NoSQL Infrastructure including ScyllaDB and Aerospike

Collaboration & Mentorship 

• Partner with the machine learning team, software engineers, and other teams to deliver integrated, high-quality solutions. 

• Provide technical guidance and mentorship to junior engineers, promoting best practices in software and data engineering. 

We’re Excited If You Have 

• 8+ years of experience in software and/or data engineering with expertise in big data technologies such as Apache Spark, Apache Airflow. 

• Expertise with at least one of the following ScyllaDB and Aerospike (preferred). 

• Strong understanding of SOLID principles and distributed systems architecture. 

• Proven experience in distributed data processing, data warehousing, and real-time data pipelines. 

• Advanced SQL skills, with expertise in query optimization for large datasets. 

• Exceptional problem-solving abilities and the capacity to work independently or collaboratively. 

• Excellent verbal and written communication skills. 

• Experience with cloud platforms such as AWS, GCP, or Azure, and containerization tools like Docker and Kubernetes. (preferred) 

• Experience in AdTech, in advertising data platforms and audience management. (preferred)

• Strong programming skills in Python, Java, and/or Scala. (preferred) 

• Knowledge of CI/CD pipelines, DevOps practices, and infrastructure-as-code tools (e.g., Jenkins & Terraform). (preferred) 

• Expertise in data modeling, schema design, and data visualization tools. Experience with building Agentic AI systems to automate decision-making and enhance analytics workflows. (preferred) 

• Bachelor's degree in computer science, Engineering, or a related field (or equivalent experience). 

#LI-GL1

About the Team 

The Ads Analytics team plays a critical role in Roku’s Advertising organization, leading measurement and analytics initiatives that power decision-making across the advertising ecosystem. We develop and manage products that deliver actionable insights for advertisers while meeting the operational and analytical needs of internal business teams. 

We work closely with Product Managers, Ad Sales, Ad Operations, Data Science, and multiple other software teams within the Advertising Engineering organization to deliver high-impact solutions.  

Looking ahead, we are exploring AI-driven measurement capabilities to further enhance the effectiveness of advertising campaigns and strengthen internal analytics. 

About the Role 

We are seeking a high skilled Senior Software Engineer with deep expertise in API Development using Spring Boot while also possessing knowledge of Apache Spark-based Big Data pipelines using Airflow. This hybrid position bridges software engineering and data engineering, requiring the ability to design, build, and maintain scalable systems for both application development and large-scale data processing. 

You will communicate and collaborate heavily with both business and engineering to ensure high quality standards and overall project delivery success. In this role, you will collaborate with cross-functional teams to architect and manage robust, production-grade data products that power critical analytics and measurement capabilities. You will work with technologies such as Apache Spark, Apache Airflow, Trino, Druid, Spring Boot, StarRocks, and Looker to deliver reliable, high-performance solutions. 

The ideal candidate is a proactive, self-motivated professional with a strong track record in building applications and services with a dedication to delivering exceptional results. 

What You’ll Be Doing 

Software Development 

• Design and build APIs and backend services using Spring Boot to support data products and analytics workflows. 

• Write clean, maintainable, and efficient code and tests, ensuring adherence to best practices through code reviews. 

Big Data Engineering 

• Design, develop, and maintain data pipelines and ETL workflows using Apache Spark and Apache Airflow. 

• Optimize data storage, retrieval, and processing systems to ensure reliability, scalability, and performance. 

• Develop and fine-tune complex queries and analytics solutions using Druid, Trino, and StarRocks for large-scale datasets. 

• Monitor, troubleshoot, and improve data systems to minimize downtime and maximize efficiency. 

Collaboration & Mentorship 

• Partner with data scientists, software engineers, and other teams to deliver integrated, high-quality solutions. 

• Provide technical guidance and mentorship to junior engineers, promoting best practices in software and data engineering. 

We’re Excited If You Have 

• 8+ years of experience in software and/or data engineering with expertise in big data technologies such as Apache Spark, Apache Airflow. 

• Expertise with at least one of the following: Apache Druid, StarRocks, and Trino. 

• Strong understanding of SOLID principles and distributed systems architecture. 

• Proven experience in distributed data processing, data warehousing, and real-time data pipelines. 

• Strong programming skills in Java, Python, or Scala.

• Advanced SQL skills, with expertise in query optimization for large datasets. 

• Expertise in data modeling, schema design, and data visualization tools.

• Experience building highly scalable, low-latency, APIs.

• Exceptional problem-solving abilities and the capacity to work both independently and collaboratively as needed. 

• Exceptional verbal and written communication skills. 

• Experience with cloud platforms such as AWS, GCP, or Azure, and containerization tools like Docker and Kubernetes. (preferred) 

• Experience in AdTech, in advertising data platforms and campaign measurement. (preferred)

• Knowledge of CI/CD pipelines, DevOps practices, and infrastructure-as-code tools (e.g., Terraform). (preferred) 

• Experience with building Agentic AI systems to automate decision-making and enhance analytics workflows. (preferred)  

• Bachelor's degree in computer science, Engineering, or a related field (or equivalent experience). 

About the Role 

We are building a next-generation observability and cloud platform that is high-performance, cost-efficient, secure, and scalable across multi-region, multi-cloud clusters. You will lead the architecture and evolution of Roku’s observability and cloud infrastructure stack. This includes metrics, logs, traces, telemetry pipelines, service mesh, developer experience, and reliability of systems that power thousands of services and millions of devices. 

You will drive a vision where developers gain deep visibility with minimal overhead, onboarding is seamless, and insights are available in real time. Your work will directly help Roku scale efficiently while maintaining reliability, cost control, and performance. 

What You’ll Be Doing 

• Architect and lead Roku’s observability platform across metrics, logs, and traces; evolve data pipelines and storage layers optimized for high throughput, performance, and cost at Roku scale (TSDBs, Parquet, distributed processing). 

• Extend and harden open‑source observability systems; overhaul core components (e.g., storage layers, query paths) to improve performance, reliability, and usability at scale. 

• Implement features such as pre‑aggregation, down-sampling, and sampling to reduce load and accelerate queries across the platform. 

• Collaborate across platform, SRE, and product teams to migrate hundreds of workloads to our common platform; augment and automate CI/CD flows and onboarding. 

• Integrate security into infrastructure and platform services; ensure robust multi‑tenant, multi‑cluster, and multi‑cloud designs. 

• Contribute improvements back to open source and CNCF‑aligned projects; shape standards adoption (OpenTelemetry, OpenMetrics) across the company. 

• Mentor engineers; establish best practices for reliability, efficiency, and cost management across service mesh and observability domains. 

What You'll have  

• Extensive experience with  software engineering with a track record of architecting distributed systems or platforms at scale. 

• Strong hands‑on experience in Golang and one scripting language (e.g., Python or Shell). 

• Experience operating observability at pb-scale ingestion and hundreds of millions of series. 

• Expertise in observability platforms and tooling (Prometheus, Grafana, Loki, Tempo, ELK/OpenSearch, ClickHouse) and standards (OpenTelemetry, OpenMetrics).  

• Deep experience building systems of scale and operating cloud infrastructure with Kubernetes; strong proficiency with service mesh technologies (Istio/Envoy), infrastructure‑as‑code (Terraform) and experience in multi‑cloud (AWS, GCP) 

• Demonstrated ability to evolve storage and query architectures for cost, scale, and latency (e.g., TSDB, Parquet, distributed processing). 

• Proven experience integrating security as part of infrastructure and platform development.   

• Exceptional cross‑functional communication; effective collaboration with both technical and non‑technical stakeholders. 

• Culture fit: independent thinker, pragmatic problem‑solver, low‑ego collaborator who moves fast and focuses on company success. 

• Experience integrating AI tools to improve processes and reduce toil. 
• Open‑source contributions in CNCF projects is preferred but not mandatory.  

#LI-PA1

#LI-GL1

About the Role

This is a senior software engineering role where you will architect, design, implement and test the run-time and native renderer of Roku's software development kit. You will partner with engineers who build the higher level scripting parts of Roku’s SDK.

Roku prides itself in building software and features which run well on our oldest devices, while taking advantage of our latest ones. To this end, the software development kit will need to be designed and implemented from the get go to run well on devices with extremely limited system resources like RAM, Flash and CPU.

What you’ll be doing

• Architect, design, implement and test the run-time and native renderer of Roku's software development kit.

• Partner with engineers who build the higher level scripting parts of Roku’s software development kit.

• Ensure that we can stand behind all APIs exposed by Roku’s software development kit, and manage the evolution of these APIs.

• Ensure that the native development kit performs well on low-cost hardware. To this end you will design for and track RAM consumption, rendering frame rate, etc.

• Develop tooling which will allow Roku and 3rd party developers to build great optimized and performant applications to run on the Roku platform.

• Navigate through ambiguous problem spaces and meticulously distill out design choices, trade-offs, and priorities.

We’re Excited If You Have

• Bachelor’s in Computer Science or Computer Engineering, or equivalent experience

• 7+ years of experience in embedded C/C++ development and toolchain.

• Extensive experience with software development on embedded Linux

• Experience with multi-process architectures and IPC mechanisms.

• Experience with UI/app frameworks from iOS or Android is a plus.

• Excellent software design and architecture skills.

• Ability to see the big picture while focused on short-term objectives and deliverables.

• Ability to multi-task and drive parallel projects and distributed teams with tight deadlines.

#LI-MS3

About the Role

This is a senior software engineering role where you will architect, design, implement and test the run-time and native renderer of Roku's software development kit. You will partner with engineers who build the higher level scripting parts of Roku’s SDK.

Roku prides itself in building software and features which run well on our oldest devices, while taking advantage of our latest ones. To this end, the software development kit will need to be designed and implemented from the get go to run well on devices with extremely limited system resources like RAM, Flash and CPU.

What you’ll be doing

• Architect, design, implement and test the run-time and native renderer of Roku's software development kit.

• Partner with engineers who build the higher level scripting parts of Roku’s software development kit.

• Ensure that we can stand behind all APIs exposed by Roku’s software development kit, and manage the evolution of these APIs.

• Ensure that the native development kit performs well on low-cost hardware. To this end you will design for and track RAM consumption, rendering frame rate, etc.

• Develop tooling which will allow Roku and 3rd party developers to build great optimized and performant applications to run on the Roku platform.

• Navigate through ambiguous problem spaces and meticulously distill out design choices, trade-offs, and priorities.

We’re Excited If You Have

• Bachelor’s in Computer Science or Computer Engineering, or equivalent experience

• 7+ years of experience in embedded C/C++ development and toolchain.

• Extensive experience with software development on embedded Linux

• Experience with multi-process architectures and IPC mechanisms.

• Experience with UI/app frameworks from iOS or Android is a plus.

• Excellent software design and architecture skills.

• Ability to see the big picture while focused on short-term objectives and deliverables.

• Ability to multi-task and drive parallel projects and distributed teams with tight deadlines.

#LI-MS3

About The Role 

With millions of users worldwide, our products have earned a reputation for "just working" seamlessly right out of the box, almost like magic. This seamless experience is no accident; it's a testament to our commitment to creating products that are not just intuitive but downright obvious. At the heart of this commitment is the Roku OS QA Team, dedicated to rigorously testing every product and feature to ensure we deliver the most reliable streaming media platform in the industry.

Our mission is simple: help people effortlessly find and stream the content they love. We achieve this through cutting-edge technology and engineering, always putting the customer at the center of everything we do.

About the Team

As part of our team, you'll leverage your diverse skills to support both Software Engineers and QA Engineers, tackling the daily challenges of their roles. Your specialist knowledge will be invaluable in suggesting improvements to enhance quality and streamline workflows, ensuring we continue to exceed our customers' expectations.

As a Senior Software Engineer (SDET), you'll be the transformational force that revolutionizes our testing approach. You'll leverage AI and advanced analytics to identify quality gaps, architect intelligent testing solutions, and establish new standards for test effectiveness that go beyond simple coverage metrics.

What you'll be doing

• Design and implement intelligent test analysis systems that identify quality gaps, predict failure patterns, and optimize test effectiveness
• Design systems that collect, analyse and act on the testing data to continuously improve on the quality processes
• Experience with systematic regression tracking and implementing process to prevent regression reoccurrence
• Establish new methodologies for measuring and improving test quality beyond simple pass/fail metrics, focusing on regression prevention and production reliability 
• Leverage AI-powered tools for automated failure analysis, root cause identification, and test flakiness scoring
• Define and implement architectural patterns that make testing more effective, maintainable, and aligned with business impact

We're excited if you have

• 5+ years of hands-on experience with test architecture and automation systems design
• 8+ years of programming experience across multiple languages with Python
• Proven track record in driving test transformation: Experience leading initiatives that significantly improved test effectiveness and reduced production issues
• AI expertise for testing: Ability to design, implement, and optimize solutions leveraging LLMs, and predictive analytics for quality assurance
• Knowledge of continuous integration tools (Jenkins/GitLab, TeamCity, AWS) and their optimization for quality gates
• Advanced test analysis skills: Experience with test flakiness analysis, failure pattern recognition, and automated root cause identification
• Excellent verbal and written communication skills with ability to influence senior leadership and cross functional teams on quality initiatives
• Some working knowledge of C++
• Leadership experience mentoring engineers and driving organizational change in testing practices
• Certifications or training in AI/ML or AI testing (e.g., Coursera AI for Everyone, Google AI Engineer, ISTQB AI Testing Foundation)

#LI-AB3

About the team

At Roku, the Device Monetization and Themed Experiences (DMTE) team, a part of the Advertising organization, is where the magic behind the scenes happens. We’re the engineers who build the high-performance graphics and UI foundations that power the FRAME engine — the core technology enabling Roku’s smooth, responsive, and visually rich experiences on millions of devices worldwide. Our work lives in the middleware and UI layers, and its impact is felt every time a user navigates a menu, enjoys an animated ad, or is wowed by the bespoke experience built to market the latest TV show or Movies. We thrive on solving the toughest technical challenges — from optimizing UI rendering to fine-tuning memory usage — using BrightScript (or JavaScript-like) to deliver rock-solid, high-performance solutions. We work in a collaborative, high-trust environment where great ideas can come from anywhere, partnering closely with firmware, UI, and product teams to ensure our platform is lightning fast, reliable, and ready for the next generation of streaming innovation. If you love building the invisible foundations that make great user experiences possible, this is the team for you.

About the role

As a Senior Software Engineer in the DMTE team, you’ll be at the heart of Roku’s platform innovation — designing, implementing, and optimizing BrightScript (or JavaScript-like) systems for graphics rendering and the FRAME engine. You’ll take on complex, performance-critical challenges that demand both creativity and precision, ensuring our devices deliver buttery-smooth visuals and instant responsiveness at scale. You’ll have the opportunity to shape core architecture, work across the stack with hardware, firmware, and application teams, and see your work directly impact tens of millions of users. This is a role for engineers who love deep technical problem-solving, care about performance down to the last millisecond, and want to work on technology that quietly powers an entire ecosystem. If you’re ready to push boundaries, mentor others, and help define the future of streaming, we’d love to hear from you.

What you'll be doing

• Build scalable UI features optimized for millions of users
• Lead technical investigations and architect solutions for complex middleware and UI challenges
• Integrate AI/ML capabilities and leverage generative AI tools to accelerate development
• Collaborate with cross-functional teams on global platform features
• Develop engineering tools and mentor junior developers
• Stay current with AI trends and emerging technologies

We're excited if you have

• 5+ years software engineering experience with UI development expertise
• Advanced BrightScript (or JavaScript-like) skills plus proficiency in Python
• Strong root cause analysis and technical communication abilities
• Knowledge of AI applications and experience with generative AI tools
• Proactive mindset with passion for continuous learning and fast iteration

#LI-NM1

About the team

At Roku, the Device Monetization and Themed Experiences (DMTE) team, a part of the Advertising organization, is where the magic behind the scenes happens. We’re the engineers who build the high-performance graphics and UI foundations that power the FRAME engine — the core technology enabling Roku’s smooth, responsive, and visually rich experiences on millions of devices worldwide. Our work lives in the middleware and UI layers, and its impact is felt every time a user navigates a menu, enjoys an animated ad, or is wowed by the bespoke experience built to market the latest TV show or Movies. We thrive on solving the toughest technical challenges — from optimizing UI rendering to fine-tuning memory usage — using BrightScript (or JavaScript-like) to deliver rock-solid, high-performance solutions. We work in a collaborative, high-trust environment where great ideas can come from anywhere, partnering closely with firmware, UI, and product teams to ensure our platform is lightning fast, reliable, and ready for the next generation of streaming innovation. If you love building the invisible foundations that make great user experiences possible, this is the team for you.

About the role

As a Senior Software Engineer in the DMTE team, you’ll be at the heart of Roku’s platform innovation — designing, implementing, and optimizing BrightScript (or JavaScript-like) systems for graphics rendering and the FRAME engine. You’ll take on complex, performance-critical challenges that demand both creativity and precision, ensuring our devices deliver buttery-smooth visuals and instant responsiveness at scale. You’ll have the opportunity to shape core architecture, work across the stack with hardware, firmware, and application teams, and see your work directly impact tens of millions of users. This is a role for engineers who love deep technical problem-solving, care about performance down to the last millisecond, and want to work on technology that quietly powers an entire ecosystem. If you’re ready to push boundaries, mentor others, and help define the future of streaming, we’d love to hear from you.

What you'll be doing

• Build scalable UI features optimized for millions of users
• Lead technical investigations and architect solutions for complex middleware and UI challenges
• Integrate AI/ML capabilities and leverage generative AI tools to accelerate development
• Collaborate with cross-functional teams on global platform features
• Develop engineering tools and mentor junior developers
• Stay current with AI trends and emerging technologies

We're excited if you have

• 5+ years software engineering experience with UI development expertise
• C++ experience in an embedded environment
• Advanced BrightScript (or JavaScript-like) skills plus proficiency in Python
• Strong root cause analysis and technical communication abilities
• Knowledge of AI applications and experience with generative AI tools
• Proactive mindset with passion for continuous learning and fast iteration

#LI-NM1

About the Role

You will be a SME and technical leader in engineering Infrastructure, productivity and enterprise tooling, partnering with globally distributed Engineering, Product and Security teams and systems.

What You’ll Be Doing

Roku is seeking a world class engineer to be a true force multiplier by owning the strategy, architecture, and long-term execution of engineering infrastructure, enterprise tooling, and AI-assisted workflow automation. This architect/strategist role drives org-wide improvements in engineering productivity, delivery throughput, quality, security posture, and cost efficiency by building platforms, working practices and automation (including AI/LLM-enabled capabilities) that scale across geographies and time zones.

Key Responsibilities

AI-First Automation & Intelligent Tooling

• Define and lead an AI-first automation roadmap for Engineering Infrastructure and Enterprise Tooling (e.g., reducing waste, accelerating reviews, improving incident response, increasing release confidence).
• Architect and ship AI/LLM-enabled workflow automation across the SDLC (e.g. risk assessment, automated build, test and deployment, intelligent test selection, change-impact analysis, auto-triage of build/test failures).
• Establish policies and guardrails for AI usage in internal tools: data handling, prompt/response logging, model/provider selection, evaluation, fallback behaviors, and abuse prevention.

Dev Productivity & Enterprise Tooling (Global Scale)

• Set technical direction and standards for the globally used developer tools, including build systems. Source code management, branching/release strategy, and self-service support tools.
• Architect and evolve, CI/CD and build/test pipelines using Jenkins, Docker, and build systems (Bazel /BitBake/Yocto  preferred) to support multi-site engineering environments.
• Own and scale test and quality workflows leveraging test management systems (e.g., TestRail or equivalent), enabling consistent traceability, reporting, and release sign-off across distributed teams.
• Drive Jira workflow design and automation (templates, guardrails, integrations) to provide consistent cross-org visibility and execution.

Workflow Automation (Cross-Functional, Cross-Geo)

• Design and implement automation spanning Engineering, Product, Marketing, and Partners (e.g., launch readiness, certification/release checklists, partner onboarding, incident/change workflows).
• Replace manual coordination with durable automation and integrations that work reliably across regions/time zones.

Security, Cost, Performance, and Reliability (Distributed Systems)

• Embed secure-by-default controls into pipelines and tooling (access control, secrets handling, audit trails, policy enforcement), including for AI-enabled systems.
• Improve build/test performance and reliability (build times, test duration, flake reduction, pipeline stability) using measurable KPIs and operational rigor.
• Drive cost efficiencies across tooling/infrastructure (compute utilization, caching strategies, license rationalization including AI/runtime costs and ROI tracking.
• This is a highly visible role and you will report directly to a Vice President of Engineering. This requires a very strong technical leader with experience in the development of consumer electronics devices. The right person for this role will have ability to collaborate well with engineering and partner teams.
• Own cross-team architectures and standards; drive adoption through influence, clear technical judgment, and sustained multi-quarter execution.
• Lead design reviews, mentor senior engineers, and unblock the hardest technical problems across distributed teams and systems.
• Provide long-term stewardship via roadmaps, operational maturity (runbooks/SLOs), and incident/postmortem practices suitable for 24/7 global operations.
• Establish yourself as the person others bring their hardest problems to

We’re Excited If You Have

• Bachelor’s in Computer Science or Computer Engineering, or equivalent experience
• Prior experience at Staff, Principal, or Architect level
• Ownership in platform/infrastructure, developer productivity, CI/CD, build systems, or workflow automation, including work spanning globally distributed teams and systems.
• Strong, hands-on knowledge of:

• • Git (workflows, branching strategies, release management)
  • Jenkins (CI/CD pipeline design, scaling, reliability)
  • Docker containers (reproducible build/test execution)

Build systems ( itBake/Yocto preferred)

• Jira (workflow design/automation, cross-team visibility)
• Test management systems (e.g., TestRail or equivalent)
• Demonstrated experience delivering automation at scale, including building platforms/components used by multiple teams.
• Strong systems thinking across security, reliability, performance, and cost tradeoffs.
• Excellent written communication (architecture docs, decision records, operating procedures).
• Experience building AI-assisted developer tooling (e.g., CI insights, test intelligence, code review automation, release risk scoring, incident copilots).
• Experience implementing evaluation/monitoring for AI systems (quality metrics, drift, offline test sets, human feedback loops).
• Extensive experience with software development on embedded Linux,  multi-process architectures and IPC mechanisms
• Experience working in large cross functional teams and ability to influence teams that don't report to you
• Ability to see the big picture while focused on short-term objectives and deliverables
• Ability to multi-task and drive parallel projects and distributed teams with tight deadlines

#LI-NM1

About the Role

You will be a SME and technical leader in engineering Infrastructure, productivity and enterprise tooling, partnering with globally distributed Engineering, Product and Security teams and systems.

What You’ll Be Doing

Roku is seeking a world class engineer to be a true force multiplier by owning the strategy, architecture, and long-term execution of engineering infrastructure, enterprise tooling, and AI-assisted workflow automation. This architect/strategist role drives org-wide improvements in engineering productivity, delivery throughput, quality, security posture, and cost efficiency by building platforms, working practices and automation (including AI/LLM-enabled capabilities) that scale across geographies and time zones.

Key Responsibilities

AI-First Automation & Intelligent Tooling

• Define and lead an AI-first automation roadmap for Engineering Infrastructure and Enterprise Tooling (e.g., reducing waste, accelerating reviews, improving incident response, increasing release confidence).
• Architect and ship AI/LLM-enabled workflow automation across the SDLC (e.g. risk assessment, automated build, test and deployment, intelligent test selection, change-impact analysis, auto-triage of build/test failures).
• Establish policies and guardrails for AI usage in internal tools: data handling, prompt/response logging, model/provider selection, evaluation, fallback behaviors, and abuse prevention.

Dev Productivity & Enterprise Tooling (Global Scale)

• Set technical direction and standards for the globally used developer tools, including build systems. Source code management, branching/release strategy, and self-service support tools.
• Architect and evolve, CI/CD and build/test pipelines using Jenkins, Docker, and build systems (Bazel /BitBake/Yocto  preferred) to support multi-site engineering environments.
• Own and scale test and quality workflows leveraging test management systems (e.g., TestRail or equivalent), enabling consistent traceability, reporting, and release sign-off across distributed teams.
• Drive Jira workflow design and automation (templates, guardrails, integrations) to provide consistent cross-org visibility and execution.

Workflow Automation (Cross-Functional, Cross-Geo)

• Design and implement automation spanning Engineering, Product, Marketing, and Partners (e.g., launch readiness, certification/release checklists, partner onboarding, incident/change workflows).
• Replace manual coordination with durable automation and integrations that work reliably across regions/time zones.

Security, Cost, Performance, and Reliability (Distributed Systems)

• Embed secure-by-default controls into pipelines and tooling (access control, secrets handling, audit trails, policy enforcement), including for AI-enabled systems.
• Improve build/test performance and reliability (build times, test duration, flake reduction, pipeline stability) using measurable KPIs and operational rigor.
• Drive cost efficiencies across tooling/infrastructure (compute utilization, caching strategies, license rationalization including AI/runtime costs and ROI tracking.
• This is a highly visible role and you will report directly to a Vice President of Engineering. This requires a very strong technical leader with experience in the development of consumer electronics devices. The right person for this role will have ability to collaborate well with engineering and partner teams.
• Own cross-team architectures and standards; drive adoption through influence, clear technical judgment, and sustained multi-quarter execution.
• Lead design reviews, mentor senior engineers, and unblock the hardest technical problems across distributed teams and systems.
• Provide long-term stewardship via roadmaps, operational maturity (runbooks/SLOs), and incident/postmortem practices suitable for 24/7 global operations.
• Establish yourself as the person others bring their hardest problems to

We’re Excited If You Have

• Bachelor’s in Computer Science or Computer Engineering, or equivalent experience
• Prior experience at Staff, Principal, or Architect level
• Ownership in platform/infrastructure, developer productivity, CI/CD, build systems, or workflow automation, including work spanning globally distributed teams and systems.
• Strong, hands-on knowledge of:

• • Git (workflows, branching strategies, release management)
  • Jenkins (CI/CD pipeline design, scaling, reliability)
  • Docker containers (reproducible build/test execution)

Build systems ( itBake/Yocto preferred)

• Jira (workflow design/automation, cross-team visibility)
• Test management systems (e.g., TestRail or equivalent)
• Demonstrated experience delivering automation at scale, including building platforms/components used by multiple teams.
• Strong systems thinking across security, reliability, performance, and cost tradeoffs.
• Excellent written communication (architecture docs, decision records, operating procedures).
• Experience building AI-assisted developer tooling (e.g., CI insights, test intelligence, code review automation, release risk scoring, incident copilots).
• Experience implementing evaluation/monitoring for AI systems (quality metrics, drift, offline test sets, human feedback loops).
• Extensive experience with software development on embedded Linux,  multi-process architectures and IPC mechanisms
• Experience working in large cross functional teams and ability to influence teams that don't report to you
• Ability to see the big picture while focused on short-term objectives and deliverables
• Ability to multi-task and drive parallel projects and distributed teams with tight deadlines

#LI-NM1

COMPANY DESCRIPTION

Mirai Bio is a Flagship-backed, privately held biotechnology company on a mission to transform the current approach to information molecule therapeutics to unlock their full therapeutic potential. In recent years, we have begun to experience the power of information molecules in treating historically undruggable diseases and in designing therapies with unprecedented turnaround times. Mirai’s platform integrates nanoparticle development with world-class informatics technologies and a novel pipeline of experimentation and discovery to drive a new generation of highly effective, therapeutically relevant information molecule therapies. We are seeking collaborative, relentless problem solvers that share our passion for impact to join us!

THE ROLE

We are seeking a Senior Director / Vice President of Scientific Strategy & Research Enablement to help architect and scale the research engine that powers this platform. Reporting to the SVP/Head of Platform, this role will operate at the intersection of scientific strategy, platform development, and execution, ensuring that our research organization has the infrastructure, partnerships, and operational frameworks necessary to move rapidly from invention to discovery.

This individual will play a key role in shaping how our science is executed—designing the systems, workflows, and external collaborations that enable scientists to focus on innovation while accelerating the generation of high-quality data and platform insights.

The ideal candidate will combine a strong understanding of modern research environments with the ability to build scalable systems that increase scientific productivity and translate platform capabilities into impactful programs.  This is an individual contributor role that is part of extended Executive Leadership team, and with opportunities for growth.

KEY RESPONSIBILITIES

Scientific Strategy and Research Enablement

• Partner closely with the SVP/Head of Platform and scientific leaders to translate research strategy into an integrated framework for execution across internal teams and external collaborators.
• Design and implement the infrastructure that supports discovery, including research workflows, collaboration frameworks, and data systems that enable efficient experimentation and decision-making.
• Identify opportunities to increase research velocity and rigor by optimizing experimental pipelines, data generation, and knowledge flow across the organization.
• Lead initiatives that remove barriers to scientific progress and improve how the organization generates, integrates, and interprets experimental data.
• Help ensure the organization’s scientific output is communicated clearly and effectively to internal and external stakeholders.
• Collaborate with research, finance, and leadership teams to align resources with the highest-impact scientific opportunities.
• Establish mechanisms for tracking research progress, milestones, and data generation across internal and partnered programs.
• Contribute to building a culture of scientific rigor, transparency, and operational excellence within the research organization.

Platform Development and External Scientific Partnerships

• Develop and manage a network of external collaborators and technology providers that extend the capabilities of the platform.
• Continuously evaluate emerging technologies, experimental capabilities, and vendors that can expand the company’s research toolkit.
• Structure and oversee scientific collaborations and SOWs to ensure alignment on experimental design, data quality and deliverables.

PROFESSIONAL EXPERIENCE & QUALIFICATIONS

Required

• Bachelor’s degree in life sciences, biotechnology, or related field; PhD required
• 10+ years of experience in biotechnology or pharmaceutical R&D, with exposure to discovery-stage research environments.
• Demonstrated experience enabling or managing complex research programs, scientific collaborations, or research infrastructure.
• Strong understanding of laboratory research workflows and modern approaches to data generation and management.
• Exceptional communication skills and the ability to synthesize complex scientific concepts into clear strategic narratives.

Preferred

• Experience in early-stage or venture-backed biotechnology companies.
• Familiarity with in vivo delivery technologies, genetic medicines, or nucleic acid therapeutics.

ABOUT FLAGSHIP PIONEERING:

Flagship Pioneering invents and builds platform companies, each with the potential for multiple products that transform human health, sustainability and beyond. Since its launch in 2000, Flagship has originated more than 100 companies. Many of these companies have addressed humanity’s most urgent challenges: vaccinating billions of people against COVID-19, curing intractable diseases, improving human health, preempting illness, and feeding the world by improving the resiliency and sustainability of agriculture.  

Flagship has been recognized twice on FORTUNE’s “Change the World” list, an annual ranking of companies that have made a positive social and environmental impact through activities that are part of their core business strategies and has been twice named to Fast Company’s annual list of the World’s Most Innovative Companies. Learn more about Flagship at www.flagshippioneering.com.

At Flagship, we accept impossible missions to enable bigger leaps. Our core values guide us through uncertainty and toward lasting impact.

We are an equal opportunity employer. All qualified applicants will be considered for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, disability, protected veteran status, or any other characteristic protected by law.

We recognize that great candidates often bring unique strengths without fulfilling every qualification. If you have some of the experience listed above but not all, please apply anyway. We are dedicated to building diverse and inclusive teams and look forward to learning more about your background and interest in Flagship.

Recruitment & Staffing Agencies: Flagship Pioneering and its affiliated Flagship Lab companies (collectively, “FSP”) do not accept unsolicited resumes from any source other than candidates. The submission of unsolicited resumes by recruitment or staffing agencies to FSP or its employees is strictly prohibited unless contacted directly by Flagship Pioneering’s internal Talent Acquisition team. Any resume submitted by an agency in the absence of a signed agreement will automatically become the property of FSP, and FSP will not owe any referral or other fees with respect thereto.

#LI-TL1

The salary range for this role is $275,000 - $340,000. Compensation for the role will depend on a number of factors, including a candidate’s qualifications, skills, competencies, and experience. Mirai Bio currently offers healthcare coverage, annual incentive program, retirement benefits and a broad range of other benefits. Compensation and benefits information is based on Mirai Bio's good faith estimate as of the date of publication and may be modified in the future.

COMPANY DESCRIPTION

Mirai Bio is a Flagship-backed, privately held biotechnology company on a mission to transform the current approach to information molecule therapeutics to unlock their full therapeutic potential. In recent years, we have begun to experience the power of information molecules in treating historically undruggable diseases and in designing therapies with unprecedented turnaround times. Mirai’s platform integrates nanoparticle development with world-class informatics technologies and a novel pipeline of experimentation and discovery to drive a new generation of highly effective, therapeutically relevant information molecule therapies. We are seeking collaborative, relentless problem solvers that share our passion for impact to join us!

THE ROLE

We are seeking a Senior Director / Vice President of Scientific Strategy & Research Enablement to help architect and scale the research engine that powers this platform. Reporting to the SVP/Head of Platform, this role will operate at the intersection of scientific strategy, platform development, and execution, ensuring that our research organization has the infrastructure, partnerships, and operational frameworks necessary to move rapidly from invention to discovery.

This individual will play a key role in shaping how our science is executed—designing the systems, workflows, and external collaborations that enable scientists to focus on innovation while accelerating the generation of high-quality data and platform insights.

The ideal candidate will combine a strong understanding of modern research environments with the ability to build scalable systems that increase scientific productivity and translate platform capabilities into impactful programs.  This is an individual contributor role that is part of extended Executive Leadership team, and with opportunities for growth.

KEY RESPONSIBILITIES

Scientific Strategy and Research Enablement

• Partner closely with the SVP/Head of Platform and scientific leaders to translate research strategy into an integrated framework for execution across internal teams and external collaborators.
• Design and implement the infrastructure that supports discovery, including research workflows, collaboration frameworks, and data systems that enable efficient experimentation and decision-making.
• Identify opportunities to increase research velocity and rigor by optimizing experimental pipelines, data generation, and knowledge flow across the organization.
• Lead initiatives that remove barriers to scientific progress and improve how the organization generates, integrates, and interprets experimental data.
• Help ensure the organization’s scientific output is communicated clearly and effectively to internal and external stakeholders.
• Collaborate with research, finance, and leadership teams to align resources with the highest-impact scientific opportunities.
• Establish mechanisms for tracking research progress, milestones, and data generation across internal and partnered programs.
• Contribute to building a culture of scientific rigor, transparency, and operational excellence within the research organization.

Platform Development and External Scientific Partnerships

• Develop and manage a network of external collaborators and technology providers that extend the capabilities of the platform.
• Continuously evaluate emerging technologies, experimental capabilities, and vendors that can expand the company’s research toolkit.
• Structure and oversee scientific collaborations and SOWs to ensure alignment on experimental design, data quality and deliverables.

PROFESSIONAL EXPERIENCE & QUALIFICATIONS

Required

• Bachelor’s degree in life sciences, biotechnology, or related field; PhD required
• 10+ years of experience in biotechnology or pharmaceutical R&D, with exposure to discovery-stage research environments.
• Demonstrated experience enabling or managing complex research programs, scientific collaborations, or research infrastructure.
• Strong understanding of laboratory research workflows and modern approaches to data generation and management.
• Exceptional communication skills and the ability to synthesize complex scientific concepts into clear strategic narratives.

Preferred

• Experience in early-stage or venture-backed biotechnology companies.
• Familiarity with in vivo delivery technologies, genetic medicines, or nucleic acid therapeutics.

ABOUT FLAGSHIP PIONEERING:

Flagship Pioneering invents and builds platform companies, each with the potential for multiple products that transform human health, sustainability and beyond. Since its launch in 2000, Flagship has originated more than 100 companies. Many of these companies have addressed humanity’s most urgent challenges: vaccinating billions of people against COVID-19, curing intractable diseases, improving human health, preempting illness, and feeding the world by improving the resiliency and sustainability of agriculture.  

Flagship has been recognized twice on FORTUNE’s “Change the World” list, an annual ranking of companies that have made a positive social and environmental impact through activities that are part of their core business strategies and has been twice named to Fast Company’s annual list of the World’s Most Innovative Companies. Learn more about Flagship at www.flagshippioneering.com.

At Flagship, we accept impossible missions to enable bigger leaps. Our core values guide us through uncertainty and toward lasting impact.

We are an equal opportunity employer. All qualified applicants will be considered for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, disability, protected veteran status, or any other characteristic protected by law.

We recognize that great candidates often bring unique strengths without fulfilling every qualification. If you have some of the experience listed above but not all, please apply anyway. We are dedicated to building diverse and inclusive teams and look forward to learning more about your background and interest in Flagship.

Recruitment & Staffing Agencies: Flagship Pioneering and its affiliated Flagship Lab companies (collectively, “FSP”) do not accept unsolicited resumes from any source other than candidates. The submission of unsolicited resumes by recruitment or staffing agencies to FSP or its employees is strictly prohibited unless contacted directly by Flagship Pioneering’s internal Talent Acquisition team. Any resume submitted by an agency in the absence of a signed agreement will automatically become the property of FSP, and FSP will not owe any referral or other fees with respect thereto.

#LI-TL1

The salary range for this role is $275,000 - $340,000. Compensation for the role will depend on a number of factors, including a candidate’s qualifications, skills, competencies, and experience. Mirai Bio currently offers healthcare coverage, annual incentive program, retirement benefits and a broad range of other benefits. Compensation and benefits information is based on Mirai Bio's good faith estimate as of the date of publication and may be modified in the future.

About Graphcore 

At Graphcore, we’re building the future of AI compute.

We’re a team of semiconductor, software and AI experts, with deep experience in creating the complete AI compute stack - from silicon and software to infrastructure at datacenter scale.

As part of the SoftBank Group, backed by significant long-term investment, we are delivering key technology into the fast-growing SoftBank AI ecosystem.

To meet the vast and exciting AI opportunity, Graphcore is expanding its teams around the world.

We are bringing together the brightest minds to solve the toughest problems, in a place where everyone has the opportunity to make an impact on the company, our products and the future of artificial intelligence

Job Summary

Applicants for this role should have strong experience designing, developing, and maintaining high-quality software systems. The role focuses on testing and validating a complex machine learning software stack, with particular emphasis on software architecture, automation, and engineering best practices.

The ideal candidate is an experienced software engineer who values code quality, testability, and long-term maintainability, and enjoys building systems that other engineers rely on. This person will be comfortable working across large codebases, contributing to CI/CD infrastructure, and shaping technical direction through thoughtful design and mentoring in a technically demanding environment spanning ML frameworks, infrastructure, and AI accelerator hardware

The Team

The ML QA team is composed of highly skilled software engineers with a strong focus on automation, software quality, and data-driven validation. The team works closely with industry-standard machine learning frameworks and models, contributing to upstream open-source projects and collaborating across the wider software organization. 

Operating in a fast-paced environment, the team plays a critical role in ensuring reliability, performance, and maintainability across the ML software stack, helping to deliver robust and high-quality products to customers. 

Responsibilities and Duties

• Design, implement, and maintain robust test infrastructure and automation for a complex ML software stack.
• Architect and evolve test frameworks and tooling with a focus on scalability, maintainability, and developer experience.
• Build and maintain CI/CD pipelines targeting simulators, emulators (e.g. QEMU), and physical hardware.
• Create representative ML workloads and gain insights from their execution. (Numerical accuracy, performance analysis and benchmarking).
• Work closely with all Software development teams, supporting a culture of quality, security and maintainability.
• Review code and designs, setting a high bar for software engineering best practices.
• Mentor and support junior engineers, helping raise the overall technical capability of the team.
• Evaluate existing test strategies and infrastructure, identifying gaps and driving improvements aligned with team and organizational goals. 

Candidate Profile

Essential:

• Experience in production-quality software engineering roles.
• Strong software design and architecture skills, with experience working on large or complex systems.
• Strong proficiency in Python, including experience building and maintaining production codebases.
• Solid experience with CI/CD systems and automated testing (preferably GitHub-based workflows).
• Experience working in Linux environments.
• Familiarity with C or C++, with the ability to read, debug, and reason about low-level code when needed.
• Proven ability to mentor junior engineers and influence engineering practices within a team.
• Strong problem-solving skills and a proactive, self-directed approach to work.
• Bachelor/Master's/PhD or equivalent experience in Computer Science, Maths, Machine Learning, Data Science, or related field. 

Desirable

• Exposure to machine learning frameworks such as PyTorch, JAX, Triton, TensorFlow
• Experience with distributed workload management systems such as Kubernetes, VLLM, Keras or MLOps pipelines
• Experience working with hardware simulators or emulators (e.g. QEMU).
• Experience developing for or working with FPGA-based systems.
• Experience with people management or mentoring 

Benefits

In addition to a competitive salary, Graphcore offers flexible working, a generous annual leave policy, private medical insurance and health cash plan, a dental plan, pension (matched up to 5%), life assurance and income protection. We have a generous parental leave policy and an employee assistance programme (which includes health, mental wellbeing, and bereavement support). We offer a range of healthy food and snacks at our central Bristol office and have our own barista bar! We welcome people of different backgrounds and experiences; we’re committed to building an inclusive work environment that makes Graphcore a great home for everyone. We offer an equal opportunity process and understand that there are visible and invisible differences in all of us. We can provide a flexible approach to interview and encourage you to chat to us if you require any reasonable adjustments.

Applicants for this position must hold the right to work in the UK. Unfortunately at this time, we are unable to provide visa sponsorship or support for visa applications

About Graphcore 

Graphcore is one of the world’s leading innovators in Artificial Intelligence compute.  

It is developing hardware, software and systems infrastructure that will unlock the next generation of AI breakthroughs and power the widespread adoption of AI solutions across every industry.  

As part of the SoftBank Group, Graphcore is a member of an elite family of companies responsible for some of the world’s most transformative technologies. Together, they share a bold vision: to enable Artificial Super Intelligence and ensure its benefits are accessible to everyone.   

Graphcore’s teams are drawn from diverse backgrounds and bring a broad range of skills and perspectives. A melting pot of AI research specialists, silicon designers, software engineers and systems architects, Graphcore enjoys a culture of continuous learning and constant innovation.

Job Summary 

We are looking for a Principal Architect to define and drive the architectural vision of the software stack for the Graphcore ML accelerator.

In this role, you will shape the architecture of our software ecosystem and maintain a deep understanding of the product’s hardware and software components, their interfaces, and how they interact.

You are an excellent communicator, and you proactively convey the software architecture.

You bring a pragmatic, trade-off-aware approach to decision-making, fully recognising the impact of architectural choices on product direction and engineering outcomes. 

The Team 

The software architecture team is responsible for defining, maintaining and communicating the overarching architecture of our software stack, from firmware to ML frameworks.

The team works within the wider software organisation, partnering closely with engineering teams who deliver against this architectural vision. 

Responsibilities and Duties

• Define & document the software architecture of the software stack.  
• Work across different software domains to ensure a coherent end too end architecture.
• Clearly communicate the software architecture to engineering teams.
• Ensure teams understand key software architectural components, interfaces, and guiding principles. 
• Continuously maintain the software architecture as the product evolves. Communicate architectural changes proactively to all relevant stakeholders. 
• Stay informed about trends and developments in the ML/software ecosystem.
• Assess the architectural impact of new technologies.
• Be aware of the usability, performance, reliability, maintainability, testability, security and observability constraints on the software architecture. 
• Prototyping and validating architectural concepts through proof-of-concept implementations. 
• Contribute to future and/or related product definitions with a forward-looking mindset, understanding and communicating the impact of future direction on software architecture. 
• Work with the HW and Silicon architects to ensure product the needs of software stack. 
• Ensure the software architecture meets the product requirements.  
• Work closely with engineering, product, leadership, and partners to ensure alignment between business goals and architectural direction. 

Candidate Profile

Essential:

• Expertise in one or more of these technologies; Firmware, Drivers, ML frameworks (PyTorch, Triton, etc), Collectives, HPC, Tooling, C & C++, CPU architectures.
• Technical expertise in the ML accelerator software space.
• Excellent communication skill, both written and verbal. 
• Collaborative mindset and ability to influence. 
• Pragmatic approach to decision making, being very aware of trade-offs and implications. 

Desirable

• Demonstrable experience in a previous architecture role. 

Benefits

• In addition to a competitive salary, Graphcore offers flexible working, a generous annual leave policy, private medical insurance and health cash plan, a dental plan, pension (matched up to 5%), life assurance and income protection. We have a generous parental leave policy and an employee assistance programme (which includes health, mental wellbeing, and bereavement support). We offer a range of healthy food and snacks at our central Bristol office and have our own barista bar! We welcome people of different backgrounds and experiences; we’re committed to building an inclusive work environment that makes Graphcore a great home for everyone. We offer an equal opportunity process and understand that there are visible and invisible differences in all of us. We can provide a flexible approach to interview and encourage you to chat to us if you require any reasonable adjustments.

  Applicants for this position must hold the right to work in the UK. Unfortunately at this time, we are unable to provide visa sponsorship or support for visa applications

Senior Solutions Architect

Role Summary

Our mission at HubSpot is to help millions of organizations grow better. As a Senior Solutions Architect, you will partner with our most strategic customers to design scalable, AI-powered solutions that drive measurable business outcomes. You'll act as both a trusted technical advisor and hands-on builder, shaping multi-quarter platform strategies while delivering AI powered tools for our team and partners. Your work will directly drive increased platform adoption, accelerate customer usage of HubSpot's AI tools and capabilities, and create reusable solutions that elevate the broader Solutions ecosystem.

What You'll Do

Build

• Drive HubSpot AI adoption by designing, building, and delivering agentic workflows and LLM-powered solutions that create measurable improvements in customer outcomes and increase platform consumption.
• Accelerate stakeholder buy-in by developing working prototypes and proof-of-concept automations that demonstrate clear, quantifiable business value and move customers from evaluation to production.
• Multiply team impact by codifying successful technical patterns into libraries, playbooks, and scaffolds that increase delivery efficiency across the Solutions and Solutions Partner ecosystem.

Advise & Lead

• Increase platform depth and utilization by translating complex, multi-portal business needs into comprehensive, scalable solution strategies across the entire HubSpot ecosystem.
• Expand AI adoption and HubSpot credit consumption by leading solution design for large-scale HubSpot AI deployment projects, identifying opportunities to unify the platform and drive efficiency gains across the customer lifecycle.
• Secure long-term customer investment by developing and championing multi-quarter technical roadmaps, aligning solution choices to business objectives and building value cases that influence director-level and senior stakeholders.
• Solve customers' GTM challenges by owning solution design for complex, multi-hub engagements that deploy agentic AI, leveraging advanced CRM features, APIs, and the broader HubSpot ecosystem.
• Protect delivery outcomes by identifying and mitigating technical risks on high-impact projects, acting as the leading technical voice on product-stretching use cases.
• Shape the HubSpot platform by providing aggregated field insights to Product and Engineering teams that directly influence roadmap decisions.

What You'll Bring

Required Qualifications

• 5+ years of experience in solution architecture, technical consulting, or similar roles within a SaaS environment, with a track record of architecting and delivering complex, business-critical solutions.
• Hands-on experience with LLM tooling: RAG architectures, agent frameworks, prompt engineering, and context management. You have built agentic workflows, not just presented them.
• Strong fluency with APIs, system integrations, and architectural design for scalable and resilient solutions.
• Proven ability to connect technical solutions to business outcomes, and to build clear value cases that secure director-level and senior stakeholder buy-in on complex solution designs.
• Deep, cross-functional understanding of how enterprise systems and processes interconnect, with the ability to orchestrate end-to-end architectures across multiple platforms.
• Strong communication and collaboration skills across technical and non-technical audiences, with experience influencing director-level decisions using data and a clear articulation of trade-offs.
• Demonstrated ability to navigate ambiguity, scope complex problems, and deliver structured solutions in fast-moving environments.

Nice-to-Have Qualifications

• Familiarity with Python/Node.js for backend services, automation pipelines, or API integrations.
• Experience working with CRM platforms or go-to-market technology ecosystems, particularly HubSpot.
• Background in building reusable frameworks, internal tools, or scalable technical assets for broader team use.
• Experience contributing to product feedback loops or directly influencing product roadmaps.

About Every Cure:   

Every Cure is an AI-driven nonprofit, biotech organization on a mission to save and improve lives by repurposing existing medicines for diseases with significant unmet need. We are working to create a world where every drug is used to treat every disease it possibly can, so that no patient suffers when an existing treatment could help them. We are filling a gap left by the current biomedical system, which doesn’t systematically pursue new uses for old drugs. Through artificial intelligence technologies, collaboration with healthcare professionals, and patient advocacy, Every Cure is dedicated to unlocking the full potential of existing medicines to treat every disease and every patient we possibly can. Inspired by Every Cure’s co-founders' work repurposing drugs for Castleman disease and other rare diseases, Every Cure is advancing repurposed treatments for neglected diseases and has been featured in The New Yorker,  New York Times, USA Today, Good Morning America and other news media. Led by a talented leadership team and an outstanding Board of Directors, Every Cure is supported through funding from leading philanthropic organizations like Chan Zuckerberg Initiative, TED’s Audacious Project, and ARPA-H. 

 Our approach:  

• AI-Powered Identification: We use advanced artificial intelligence to analyze the world’s biomedical knowledge and identify FDA-approved drugs that can be repurposed for untreated conditions. This cutting-edge technology enables us to explore new therapeutic possibilities efficiently.  
• Open-Source Commitment: We are dedicated to making our predictive pipeline open-source, fostering collaboration and transparency within the scientific community and unlocking the potential for discovering new treatments.  
• High-Impact Focus: We prioritize drug repurposing opportunities that will relieve the most suffering and have the greatest impact possible.  
• Rigorous Validation: Promising opportunities are thoroughly validated through laboratory and clinical studies to confirm their efficacy and safety before advancing to broader application.  
• Strategic Marketing and Access: We disseminate information about effective repurposed treatments through multiple channels and are committed to ensuring that new cures are accessible to all patients.

Applicants must reside in the state specified at the top of this job posting. Residency in that state is a requirement for consideration and must be maintained for the duration of employment.

The Head of Clinical Development leads Every Cure’s clinical research and development function, serving as both strategic architect and working clinical lead on priority programs. They manage a diverse portfolio of drug repurposing initiatives including Every Cure-sponsored interventional trials (with full sponsor IND accountability and REMS complexity where applicable), collaborative investigator-sponsored trials, and Every Cure-led patient registries, natural history studies, and other real-world studies. They collaborate directly with computational and data science teams to translate AI-driven repurposing hypotheses into clinically testable programs and represent the organization to external partners and stakeholders. This role owns sponsor compliance under ICH E6(R3) including maintenance of the clinical QMS and SOP infrastructure regardless of CRO engagement  and oversees regulatory strategy and dissemination. The HCD supports Every Cure’s CSO and engages directly with external stakeholders including CROs, clinical trial technology vendors, academic investigators, patient advocacy organizations, the IRB of record, and FDA. The HCD helps build and lead a lean internal clinical development team, modeling the working-leader norm expected in a small, mission-driven organization.

How you will make an impact: 

Strategic Leadership of Clinical Development and Medical Affairs

• Set the direction for Every Cure’s clinical research and development, ensuring alignment with the organization’s mission to repurpose FDA-approved drugs for high-impact unmet needs, while personally leading or co-leading priority programs.
• Lead the execution of organizational goals through operational planning and cross-functional integration, personally owning project timelines, quality standards, and accountability metrics for priority programs rather than delegating all execution.
• Provide expert counsel to the CSO, President and Scientific Advisory Council on medical strategy, program development, and organizational growth.

Research and Clinical Development Oversight

• Design, author, and review key study documents (protocols, statistical analysis plans, informed consent documents, clinical study reports, investigator brochures) for Every Cure-sponsored clinical trials, patient registries, natural history studies, and real-world evidence assessments. Own study design decisions end-to-end, from scientific rationale through data integrity and analysis.
• Serve as sponsor medical lead and/or medical monitor on Every Cure-sponsored IND-holding studies (delegating per-study where appropriate), ensuring all research activities are ethically sound, methodologically rigorous, and regulatory compliant under FDA 21 CFR Part 312, ICH E6(R3), and ICH E9 principles.
• Translate complex medical findings into strategic decisions regarding program continuation, optimization, or sunsetting, based on efficacy, feasibility, and patient impact.
• Responsible for compliance and oversight of the Human Subjects Research program at Every Cure, including IRB (Advarra) submissions and amendments, sponsor safety reporting (IND safety reports, DSURs), SAE adjudication, signal detection, and REMS program participation where applicable (e.g., lenalidomide).

Portfolio Strategy and Program Management

• Partner on strategic prioritization and dynamic management of Every Cure’s diverse portfolio of drug repurposing opportunities, applying a risk-adjusted, impact-oriented lens to maximize outcomes.
• Direct the progression of programs through clinical and dissemination stages, using insights from AI models and external scientific inputs. Personally lead CRO and clinical technology vendor selection, contracting input, and ongoing governance (joint steering committees, KPIs, oversight plans) for highest-priority programs.
• Develop and manage resource allocation frameworks across disease areas and therapeutic modalities, ensuring optimal investment of time, talent, and funding toward the most promising interventions.

Leadership and Team Development

• Build, mentor, and lead a lean, high-performing team of clinical research and medical professionals united around a shared vision of maximizing patient impact through drug repurposing, modeling a working-leader norm in which senior leaders contribute directly alongside their teams.
• Define roles, responsibilities, and performance standards for the clinical team while fostering a culture of excellence, integrity, psychological safety, and cross-functional collaboration.
• Promote continuous learning and growth through coaching, training programs, and development opportunities that build both individual capability and team effectiveness.

Stakeholder Engagement, Compliance, and Dissemination

• Act as medical spokesperson and lead regulatory interface for Every Cure in public, scientific, and regulatory forums (including FDA pre-IND and Type B/C meetings), promoting the organization’s mission and sharing results from preclinical and clinical programs.
• Cultivate and manage partnerships with CROs, patient advocacy groups, academic institutions, and regulatory agencies to ensure successful execution and wide-scale impact of therapeutic programs.
• Guide the regulatory approval and post-study dissemination strategies to ensure timely and effective translation of research into therapies accessible to patients, including peer-reviewed publications, policy briefs, and healthcare provider outreach.
• Partner with the Impact lead to provide input and perspective on dissemination and to engage with key stakeholders to ensure medicines reach patients.

What you bring to the team:

Education 

• MD or MD/PhD preferred; PhD DO, or PharmD acceptable

Work Experience (Two-Tier: Head of / VP)

• Minimum for Head of Clinical Development: 8+ years of clinical development experience post-MD (or equivalent), including service as clinical lead on at least one sponsor-held Phase 2 trial from protocol through database lock.
• Demonstrated leadership experience recruiting, mentoring, and managing cross-functional clinical teams, with explicit willingness and proven ability to work hands-on alongside direct reports in a small-organization setting.
• Expertise in drug development, clinical trial design (including interventional trials in rare or ultra-rare populations), and clinical decision-making.
• Sponsor-side experience running Phase 2 trials (distinct from CRO or academic investigator experience).
• Experience working across more than one therapeutic research area.
• Experience with small-sample trial designs and natural history or registry data.
• Proven leadership in driving strategic initiatives and cross-functional collaboration to advance scientific and organizational goals.

Preferred for Vice President designation:

• 12+ years of clinical development experience, including prior functional leadership at a sponsor (Executive Director, Head of, or VP level); multiple sponsor-held INDs led through Phase 2 or beyond; direct experience with REMS programs, risk-based monitoring, or similarly complex regulatory programs; and prior responsibility for building or scaling a clinical QMS under ICH E6(R3) or predecessor standards.

Skills 

• Proficiency in clinical research, real-world evidence assessments, evidence generation, patient registry design, clinical trial execution, and sponsor-side pharmacovigilance.
• Working knowledge of FDA IND regulations (21 CFR Part 312), ICH E6(R3) Good Clinical Practice, ICH E9 statistical principles, 21 CFR Part 11 for electronic records, and REMS program requirements; familiarity with EU CTR a plus.
• Exceptional communication and presentation abilities.
• Demonstrated ability to foster and sustain a collaborative, cross-functional culture grounded in shared organizational mission and values.
• Able to partner effectively with computational and data science teams and critically evaluate AI/ML-driven repurposing hypotheses for clinical translatability.
• Strategic thinker with a focus on urgency, efficiency, and impact.
• Passionate about Every Cure’s mission and values.
• Highly adaptable, thriving in a fast-paced, start-up environment.
• Explicit willingness to be hands-on: comfort authoring and reviewing key clinical documents (protocols, SOPs, CSRs), directly managing vendor/CRO relationships, and working alongside junior staff rather than exclusively through delegation. Candidates seeking a purely oversight or figurehead role are not a fit for this position.

Compensations & Benefits: 

• Your paycheck: Competitive salary based on experience, ranging from $250,000 - $275,000 annually. 
• Health and wellness: Comprehensive plans with medical, dental, and vision coverage, plus a Flexible Spending Account (FSA) for eligible healthcare expenses. 
• Future nest egg: A 403(b)-retirement plan with an employer match of 3.5% helps you save for your future. 
• Relax and recharge: Generous time off, including paid time off and paid holidays. 
• We have you covered: Comprehensive paid leave for family and medical needs, ensuring you have the support you need during important times. 

This role is based in Cambridge, MA, with an expectation of minimum 3 days per week in office.  

Every Cure is an Equal Opportunity Employer. We celebrate diversity and are committed to creating an inclusive environment for all employees. We provide equal employment opportunities to all employees and applicants for employment without regard to race, color, religion, sex, national origin, age, disability, genetics, or any other characteristic protected by federal, state, or local laws.

MORSE is seeking a talented Robotics Software Engineer to join our team. The ideal candidate will have a strong background in embedded systems, navigation algorithms, and autonomy. You will be responsible for architecting systems, implementing custom algorithms, and integrating novel control systems into our aerial vehicles. This role will involve developing and debugging software, configuring systems for flight tests, and supporting the end-to-end development of prototype vehicles. A passion for innovation and the ability to bring novel Unmanned Aerial Systems (UAS) from concept to flight is essential.

Responsibilities:

• Architect systems with multiple microcontrollers, defining component roles and managing requirements.

• Implement custom navigation algorithms and autonomy logic in Rust and C++.

• Analyze vehicle flight logs and debug GNC and autonomy issues

• Develop and write LIDAR sensor drivers in C++ and Rust.

• Handle system configuration, ground station setup, and data management during local and remote flight tests.

• Develop control and path planning algorithms for aerial vehicles and integrate them into the PX4 ROS communications layer.

• Implement drivers for novel control actuation and integrate them into PX4 or other flight controllers.

• Incorporate flight models into the existing Python flight simulator and use the simulator for algorithm development.

• Develop Software-In-the-Loop (SWIL) and Hardware-In-the-Loop (HWIL) testing capabilities.

• Aid in system architecture, selection, and integration of flight controllers, electronics, and sensors.

• Support the development, integration, and testing of prototype vehicles.

• Write, test, and debug drivers such as CANopen actuators and beyond line-of-sight radios in C++ and Python.

• Demonstrate familiarity with low-level embedded programming concepts such as memory management, data structures, algorithms, and bit manipulation.

Requirements:

• U.S. Citizenship required and ability to obtain a U.S. Security Clearance

• Bachelor’s degree in Robotics, Electrical Engineering, Computer Engineering, Computer Science, Aerospace Engineering or a related field. Master’s degree preferred.

• Strong skills in C++, Rust, and Python.

• Experience in navigation algorithms (SLAM, path planning) and autonomy logic.

• Experience with low-level embedded programming and microcontrollers.

• Experience with PX4 or other flight controllers

• Skilled in system architecture, component definition, and integration of prototype vehicles.

• A passion for taking novel UAS from concept to flight!

Flagship Pioneering is a scientific innovation engine that invents and builds companies that change the world. We bring together the greatest scientific minds with entrepreneurial company builders and assemble the capital to allow them to take courageous leaps in human health, sustainability, and beyond. 

What sets Flagship apart is our ability to advance biotechnology by uniting life science innovation, company creation, and capital investment under one roof in a way that is largely without precedent. Our team of scientists, entrepreneurial leaders, and professional capital managers are each aligned around an institutionalized process that enables us to innovate and create breakthroughs for the benefit of people and planet.

Many of the companies Flagship has founded have addressed humanity’s most urgent challenges: vaccinating billions of people against COVID-19, curing intractable diseases, improving human health, preempting illness, and feeding the world by improving the resiliency and sustainability of agriculture.

Flagship has been recognized twice on FORTUNE’s “Change the World” list, an annual ranking of companies that have made a positive social and environmental impact through activities that are part of their core business strategies, and has been named four times to Fast Company’s annual list of the World’s Most Innovative Companies.

Position Overview

Flagship Pioneering is seeking an experienced and strategic Vice President or Senior Vice President, Total Rewards and People Operations to lead the design, management, and evolution of Total Rewards programs and key people infrastructure across our ecosystem. The scope of this role spans compensation, executive compensation, equity, benefits, people operations, and people analytics for Flagship and its portfolio of companies.

This is a highly visible leadership role requiring deep expertise in compensation strategy and private-company equity, as well as the ability to operate effectively across a complex, fast-paced, and highly matrixed environment. The ideal candidate will bring strong executive presence, sound judgment, and the ability to translate business strategy into scalable people programs that support growth, innovation, and organizational effectiveness.

This leader will oversee an established team across Compensation, Benefits, People Operations, and People Analytics, and will be expected to shape a modern, market-relevant Total Rewards philosophy, refine equity and incentive structures, advance benefits strategy, and drive people insights that support executive decision-making.

Key Responsibilities

Total Rewards Strategy and Leadership

• Lead the strategy, design, and ongoing evolution of Flagship’s global Total Rewards philosophy across compensation, executive compensation, equity, benefits, and other reward programs. 
• Serve as the principal architect of rewards strategy, recommending program direction to senior leadership and ensuring alignment with business priorities, talent strategy, and financial objectives. 
• Develop and refine salary structures, incentive frameworks, equity guidelines, and market positioning approaches across a global footprint. 
• Oversee job architecture and leveling governance in support of internal equity, talent management, and scalable compensation decision-making. 
• Guide annual compensation planning processes, including merit, bonus, promotion, and other pay actions, in partnership with HR, Finance, and business leadership. 
• Partner closely with Talent Acquisition and HR Business Partners on executive and broad-based offer strategy, market competitiveness, and internal equity. 
• Lead the continued evolution of executive compensation and broad-based equity strategy across Flagship and applicable portfolio companies. 

Equity and Incentive Design

• Provide strategic leadership for complex equity and long-term incentive programs, including private-company equity structures and alternative long-term incentive constructs. 
• Oversee equity strategy, governance, and operational execution through the team, ensuring strong program design and scalable administration. 
• Partner with senior leadership on the design and refinement of incentive and ownership frameworks that support attraction, retention, and long-term value creation. 
• Bring familiarity with innovative and non-traditional compensation approaches, including profits interests, carried interest, and related long-term incentive structures. 

Benefits Strategy

• Lead benefits strategy across health and welfare, retirement, leave, and ancillary programs, ensuring programs remain competitive, sustainable, and aligned with organizational values and workforce needs. 
• Partner with the Benefits leader and external advisors to evaluate plan design, funding, market trends, vendor performance, and evolving regulatory requirements. 
• Support harmonization and modernization of benefits strategy where appropriate across a diverse and growing ecosystem. 

People Operations

• Oversee key People Operations functions, including onboarding, offboarding, employee lifecycle processes, policy administration, compliance workflows, service delivery, and operational process excellence. 
• Ensure people processes are scalable, well-governed, and designed to support a high-quality employee and manager experience. 
• Partner effectively across HR, Payroll, IT, Legal, and Finance to improve operational efficiency and strengthen people-related infrastructure. 
• Provide leadership on HR compliance, as well as compensation- and benefits-related compliance considerations, in partnership with internal and external experts as appropriate. 

People Analytics

• Lead the People Analytics agenda, with an emphasis on generating insights that support executive decision-making across workforce planning, hiring, retention, compensation, and organizational effectiveness. 
• Oversee dashboards, reporting, and analytical frameworks that inform leaders including the CEO and CFO. 
• Translate data and analysis into actionable recommendations in partnership with HR Business Partners and business leaders. 
• Advance a thoughtful, increasingly sophisticated analytics capability that supports better people decisions across Flagship and the broader ecosystem. 

Portfolio Company Partnership

• Advise and support portfolio company leaders on Total Rewards strategy, with involvement calibrated to company stage, maturity, and business need. 
• Tailor rewards frameworks and guidance for a range of company stages while maintaining sound governance and alignment with broader talent and value creation goals. 
• Present recommendations and insights to portfolio company leadership and boards as needed. 

Leadership and Team Development

• Lead, develop, and inspire a multi-functional team spanning Compensation, Benefits, People Operations, and People Analytics. 
• Foster strong collaboration across functional teams and help continue building a high-performing, service-oriented, and strategically focused organization.
• Manage external consultants, brokers, survey providers, and other key vendors in support of rewards strategy and operational excellence. 

Qualifications

• 15+ years of progressive experience in Total Rewards, with significant depth in compensation strategy and experience leading broad, multi-functional teams. 
• Deep expertise in compensation design, market benchmarking, executive compensation, incentive strategy, and private-company equity. 
• Strong familiarity with alternative long-term incentive structures, including profits interests, carried interest, and other innovative ownership or reward constructs. 
• Experience leading or advising on benefits strategy, including health and welfare, retirement, leave, and ancillary offerings. 
• Experience overseeing or partnering closely with People Operations and People Analytics functions in complex organizations. 
• Demonstrated success operating in high-growth, founder-led, venture-backed, private equity, or similarly dynamic business environments. 
• Experience supporting global workforces and navigating matrixed organizations with multiple stakeholders and business models. 
• Strong executive presence with the ability to influence senior leaders, present compelling recommendations, and operate as a trusted advisor. 
• Proven ability to translate data and market insights into practical, business-relevant decisions and action plans. 
• Experience working with boards, founders, and senior executive stakeholders preferred. 
• Prior life sciences or biotechnology experience preferred, but not required. 

Why Join Flagship Pioneering?

This is a rare opportunity to play a critical role in shaping how a highly innovative organization rewards, supports, and scales exceptional talent. As Senior Vice President, Total Rewards and People Operations, you will operate at the intersection of business strategy, organizational design, and cutting-edge science, helping to build and evolve the people infrastructure that supports transformative work in human health and sustainability.

At Flagship, we recognize there is no perfect candidate. If you have some of the experience listed above but not all, please apply anyway. Experience comes in many forms, skills are transferable, and passion goes a long way. We are dedicated to building diverse and inclusive teams and look forward to learning more about your unique background.

Recruitment & Staffing Agencies: Flagship Pioneering and its affiliated Flagship Lab companies (collectively, “FSP”) do not accept unsolicited resumes from any source other than candidates. The submission of unsolicited resumes by recruitment or staffing agencies to FSP or its employees is strictly prohibited unless contacted directly by Flagship Pioneering’s internal Talent Acquisition team. Any resume submitted by an agency in the absence of a signed agreement will automatically become the property of FSP, and FSP will not owe any referral or other fees with respect thereto.

#LI-NM1

The salary range for this role is $300,000 - $400,000. Compensation for the role will depend on a number of factors, including a candidate’s qualifications, skills, competencies, and experience. Flagship Pioneering currently offers healthcare coverage, annual incentive program, retirement benefits and a broad range of other benefits. Compensation and benefits information is based on Flagship Pioneering's good faith estimate as of the date of publication and may be modified in the future.

Required:

• 3+ in Windows desktop application development using Windows App SDK, WinUI (or similar), C#, XAML — and ideally additional experience with native Windows code (C++, Win32/WinRT/COM).
• Deep understanding of Windows application architecture, including interop between managed code (.NET) and native code.
• Proven track record of designing, building, and shipping production-quality desktop applications, with an emphasis on reliability, performance, scalability, and maintainability.
• Strong experience with accessibility APIs on Windows (e.g. Microsoft UI Automation or similar), and a dedication to building accessible and inclusive software.
• Excellent software engineering fundamentals: OOP, design patterns, data structures, algorithms, memory management, multi-threading or asynchronous programming (where relevant).
• Experience leading technical design, mentoring other engineers, conducting code reviews, and making architecture-level decisions.
• Strong communication skills; ability to articulate tradeoffs, collaborate with cross-functional teams, and drive consensus.
• A user-centric mindset: focus on building polished, intuitive, and accessible experiences for end users.

Preferred / Bonus:

• Experience with writing automated tests for UI — unit tests, integration tests, UI automation tests; familiarity with relevant testing frameworks.
• Experience with performance optimization for desktop apps (memory usage, startup time, rendering performance, high-DPI support, responsiveness under load).
• Experience with localization/globalization, right-to-left UI support, internationalization, accessibility for multiple regions.
• Familiarity with telemetry, analytics, crash reporting, logging, and error monitoring in desktop applications.
• Previous experience in shaping CI/CD workflows, release pipelines, and deployment strategies for desktop applications.
• Demonstrated ability to take ownership of feature areas or modules and drive them long-term, including maintenance, refactoring, and technical debt management.

What we offer

• A high-impact role: you will define architecture, shape the future of our Windows product, and directly influence what millions of users see and experience.
• A collaborative, flat-structure engineering culture — you are not just a coder, but a builder and a decision-maker.
• Opportunities to lead — mentor others, steer technical direction, and grow into broader technical leadership (e.g. Tech Lead, Architect).
• Flexibility, autonomy, and responsibility: you define how to solve problems, own features end-to-end, and contribute to long-term product vision.
• A purpose-driven mission: building software that’s reliable, accessible, and user-centered — making a real difference for people.

The United States Based Salary range for this role is: 140,000-200,000 USD/Year + Bonus + Stock depending on experience             

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Speechify is committed to a diverse and inclusive workplace. 
Speechify does not discriminate on the basis of race, national origin, gender, gender identity, sexual orientation, protected veteran status, disability, age, or other legally protected status.

About the team

At Roku, the UI Systems team builds the high-performance engines and core graphics infrastructure that power millions of devices. We own the low-level C++ frameworks, rendering pipelines, and system architectures that enable smooth navigation and rich animations. Our work sits at the intersection of hardware and software, where we optimize graphics rendering, memory management, and layout engines to ensure a consistent, lightning-fast experience across our entire device portfolio. We operate in a collaborative, high-trust environment, partnering closely with firmware and silicon teams to push the boundaries of what’s possible on embedded hardware.

About the role

As a Senior Software Engineer, you will be a key architect of the core systems that underpin Roku’s user experience. You will design and implement performance-critical code within our UI engine, focusing on graphics primitives, memory efficiency, and hardware acceleration. You’ll tackle complex systems-level challenges—such as optimizing frame rates on resource-constrained hardware and building robust APIs for higher-level frameworks. This role is ideal for engineers who thrive on low-level systems programming, care about performance down to the microsecond, and want to build the high-performance foundations that power the future of television.

What you’ll be doing

• Architect and optimize core C++ UI frameworks and rendering engines to ensure buttery-smooth performance across a diverse range of hardware profiles.
• Lead technical investigations into system-level bottlenecks, memory leaks, and GPU/CPU synchronization issues.
• Develop and maintain low-level graphics APIs and layout systems that serve as the backbone for Roku’s application ecosystem.
• Integrate AI/ML capabilities at the systems level, leveraging generative AI tools to optimize code generation and automate performance profiling.
• Collaborate with firmware and driver teams to leverage hardware-specific optimizations and ensure seamless integration with the underlying OS.
• Mentor junior developers through deep-dive code reviews, architectural design sessions, and technical documentation of core systems.
• Drive engineering excellence by implementing advanced debugging tools, automated performance regression suites, and modern C++ best practices.

We’re excited if you have

• Minimum of 5+ years of software engineering experience with a heavy focus on C++ (C++14/17/20).
• Deep understanding of systems programming, including memory management, multi-threading, and hardware-software abstraction layers.
• Experience with graphics APIs (e.g., OpenGL, Vulkan, or proprietary embedded graphics stacks) and rendering pipelines.
• Proficiency in Python for tooling and automation, with a working knowledge of BrightScript or JavaScript being a significant plus.
• Strong root cause analysis skills, specifically using tools like GDB, Valgrind, or platform-specific profilers.
• Knowledge of AI applications and hands-on experience using generative AI tools to accelerate systems-level development.
• A proactive mindset with a passion for squeezing every drop of performance out of embedded systems and a commitment to data-driven optimization.

About the team

At Roku, the UI team builds the foundational frameworks, tooling, and high‑performance UI components that power experiences across millions of devices. We own the middleware and UI layers that enable smooth navigation, responsive interactions, rich animations, and consistent developer workflows across the platform. Our work spans graphics rendering, layout and animation systems, performance optimization, and developer APIs that make it easy to create reliable, visually compelling applications at scale. We operate in a collaborative, high‑trust environment and partner closely with firmware, platform, and product teams to ensure the end‑to‑end experience is fast, robust, and ready for what’s next.

About the role

As a Senior Software Engineer on the UI team, you’ll design, implement, and optimize systems that underpin Roku’s user experience and developer platform. You’ll work on performance‑critical code paths for graphics rendering, animation, layout, and UI frameworks, ensuring buttery‑smooth visuals and instant responsiveness across a wide range of devices. You’ll help shape core architecture, collaborate across the stack with hardware, firmware, and application teams, and see your work directly impact tens of millions of users. This role is ideal for engineers who love deep technical problem‑solving, care about performance down to the last millisecond, and want to build the invisible foundations that make great user experiences possible.

What you’ll be doing

• Build scalable UI features optimized for millions of users
• Lead technical investigations and architect solutions across middleware, UI frameworks, and rendering pipelines
• Integrate AI/ML capabilities and leverage generative AI tools to accelerate development and improve developer productivity
• Collaborate with cross‑functional teams to deliver global platform features with measurable performance and reliability gains
• Develop engineering tooling, frameworks, and automated workflows that raise developer efficiency and code quality
• Mentor junior developers through design reviews, pair programming, and clear technical documentation
• Stay current with platform, graphics, and AI trends; proactively identify opportunities to improve performance and developer experience

We’re excited if you have

• Minimum of 5+ years of software engineering experience with a focus on UI frameworks or application development
• Advanced BrightScript (or JavaScript‑like) skills and proficiency in Python
• Experience using Typescript is a plus!
• Knowledge and hands-on experience using C++
• Strong root cause analysis skills and clear, effective technical communication
• Knowledge of AI applications and hands‑on experience with generative AI tools and workflows
• A proactive mindset with passion for continuous learning, fast iteration, and data‑driven optimization

#LI-NM1

Why Join Us?

Parabilis Medicines is a clinical-stage biopharmaceutical company dedicated to creating extraordinary medicines that unlock high-impact protein targets long-considered undruggable. The company has developed a new class of stabilized, cell-penetrant alpha-helical peptides – Helicons™ – capable of modulating intracellular proteins that are inaccessible to traditional drug modalities.

Headquartered in Cambridge, Mass., Parabilis is advancing a focused pipeline of multiple first-in-class therapies across both rare and common cancers. Its lead asset, zolucatetide (FOG-001), is a first-in-class, clinically validated direct inhibitor of the interaction between β-catenin and the T-cell factor (TCF) family of transcription factors, implicated in millions of cancer cases annually, including in colorectal cancer, desmoid tumors, hepatocellular carcinoma and a range of other Wnt/β-catenin-driven tumors. In Phase 1 clinical trials, zolucatetide produced the first-ever clinical evidence that it can directly inhibit this interaction, once previously considered “undruggable” despite its role across multiple cancer types. Parabilis is also advancing investigational degraders of ERG and ARON into clinical development for the treatment of prostate cancer, as well as progressing other preclinical programs. Backed by a recent $305 million Series F financing, Parabilis is entering an exciting phase of growth and execution.

What’s the opportunity?

This is a rare opportunity to shape and protect the intellectual foundation of a company redefining what’s possible in drug discovery. As Director, Intellectual Property, you will architect and lead the global IP strategy for Parabilis’ Helicon™ platform and pipeline—helping unlock the full value of therapies targeting proteins long considered “undruggable.”

Reporting to the General Counsel, you will operate at the intersection of cutting-edge science and business strategy, partnering closely with Research, Development, CMC, and Business Development to translate breakthrough innovation into durable competitive advantage.

In this highly visible role, you will not only build and scale world-class IP for the organization but also serve as a key strategic advisor to senior leadership—guiding critical decisions across pipeline advancement, partnerships, and long-term value creation.

Key Responsibilities:

• Develop and execute global patent strategies aligned with corporate, R&D, and business objectives.
• Design layered IP protection strategies covering composition of matter, methods of treatment, platform technologies, computational methods, and manufacturing.
• Lead drafting and prosecution of U.S. and international patent applications.
• Conduct invention mining sessions and proactively identify patentable subject matter.
• Oversee global prosecution strategy and manage outside counsel.
• Lead freedom-to-operate analyses and patent landscape assessments.
• Support due diligence for partnerships, collaborations, and financing transactions.
• Serve as primary IP advisor to Research, Clinical, Regulatory, CMC, and Business Development teams.
• Manage IP budgets and implement scalable portfolio tracking systems.
• Present IP strategy updates to senior leadership and Board as needed.

What you’ll need to be successful:

• Ph.D. in chemistry, biochemistry, molecular biology, structural biology, peptide chemistry, protein engineering, or related discipline strongly preferred.
• Registered U.S. Patent Agent or admitted U.S. Patent Attorney in good standing.
• 5+ years of patent experience in biotechnology, including in-house or law firm experience supporting innovative therapeutic platforms.
• Strong familiarity with peptide therapeutics, intracellular delivery systems, oncology drug discovery, and computational drug discovery technologies.
• Demonstrated success building patent estates for platform biotech companies.
• Deep understanding of U.S. and global patent law relevant to life sciences.
• Excellent scientific writing, claim drafting, and strategic communication skills.
• Demonstrated ability to utilize AI tools for day-to-day work; baseline proficiency is expected, and advanced or innovative use of AI is a strong plus.
• Ability to work hybrid preferred; remote considered.

Core Values

Parabilis Medicines is a team of passionate pioneers who are trailblazing the future of precision medicine with the aim of making a meaningful difference in the lives of patients. The company is committed to promoting an inspiring and flourishing working environment for all employees across the business, in all departments, and driving innovation for patient benefit.

• Growth-Minded. We’re inventing a new class of medicines—one applicable to therapeutic targets that have been dreamt about, but always considered impossible to drug. Our work requires us to be curious, humble and adaptable.
• In(ter)dependent. We are fiercely independent as a leader in defying the limitations of current therapeutic modalities, and interdependent as a team as we work collaboratively to shift drug discovery paradigms and provide patients with better treatment options.
• Patient-focused. We are deeply focused on patient outcomes, and all energy in the company is focused on science as it translates to patient impact.
• All-In. We’re All-In on solving some of the hardest scientific challenges and delivering one of the most effective new classes of drugs in history.

The base salary range for this position is $220,000-$290,000 per year, depending on experience, qualifications, and internal practices. Parabilis’s total compensation package also includes an annual target bonus, equity, and a comprehensive suite of competitive benefits designed to support our employees’ overall well-being.

As an equal opportunity employer, Parabilis Medicines values an inclusive workplace and welcomes applicants of all backgrounds and experiences. All qualified applicants will receive consideration for employment without discrimination on the basis of race, color, religion, sex, sexual orientation, gender identity, national origin, protected veteran status, disability, or any other factors prohibited by law.

30 Acorn Park Drive    |     Cambridge, MA 02140    |    www.parabilismed.com

Your Impact at LILA

We are looking for a Program Lead to own the strategy and execution of our Life Science artificial intelligence science factory (AISF) Program. This is a single-point-of-accountability role: you will design and execute a plan that is maximally responsive to the priorities of the Product, Revenue, and Science teams while leveraging and extending the Lila tech stack. Success requires deep collaboration with stakeholders, representation of the strategy to the executive team, and driving progress via delegative leadership, where cross-functional Project Teams execute the strategy via our team-of-teams operating model.

Life Science AISFs span capabilities in cell biology, protein science, nucleic acid science, small molecule therapeutics, and targeted delivery — the experimental backbone that enables our AI to learn from biology at scale. This role sits at the intersection of deep domain expertise and strategic platform development, making it one of the most technically consequential leadership positions at Lila.

What You'll Be Building

Program Ownership

• Define the "How and When" in response to strategic "What and Why" inputs from Product, Science, and AI teams
• Propose, negotiate, and own Program Charters for Life Science AISFs, including scope, budget, timeline, and success criteria
• Collaborate with Finance to dynamically manage program budget and strategy throughout execution, escalating or reallocating as needed

Technical Leadership

• Architect the strategy for expanding Life Science AISF capabilities across cell, protein, nucleic acid, small molecule screening, and delivery experimental platforms, in close coordination with the Product, AISF Engineering, Software, Robotics, and Life Science Experiment teams
• Evaluate proof-of-concept results from frontier Science Programs (e.g., Autoimmunity, Solid Tumor, Protein Persistence), align with Product on their value creation potential, and design their integration into the Life Science AISF platform
• Ensure new platform capabilities are well-scoped, derisked, and positioned to accelerate downstream Intelligence Programs
• Maintain and extend Lila's best-in-world autonomous science platform for life sciences
• Design the Life Science AISF to be a maximally expressive lab with unprecedented responsiveness to AI guidance

Team and Execution Management

• Form and advise Life Science Project Teams; ensure teams have the resources, clarity, and support to execute autnomously
• Coordinate with Science Program Leads whose work depends on Life Science AISF capabilities
• Resolve resourcing conflicts within your program via collaboration with Product; escalate to senior leadership when a solution aligned to the approved charters cannot be identified

Stakeholder Communication

• Represent Life Science AISF programs in Technical Leadership Team (TLT) reviews
• Communicate program status, risks, and strategic decisions to TLT and cross-functional partners

What You’ll Need to Succeed

• PhD or equivalent experience in a life sciences discipline (cell biology, biochemistry, molecular biology, or related field), with substantial postdoctoral or industry research experience
• Track record of leading complex, multi-disciplinary experiment and lab automation programs
• Familiarity across multiple Life Science AISF domains (cell-based assays, protein characterization, nucleic acid workflows, or delivery systems)
• Experience with autonomous experiment platforms
• Experience defining and managing technical roadmaps with resource and timeline constraints
• Strong written and verbal communication, coupled with the ability to translate technical depth into strategic clarity for diverse audiences

Bonus Points For

• Familiarity with AI/ML-driven experimental design or closed-loop science workflows
• Prior experience in a fast-paced, technology-driven research environment (biotech, pharma, or deep-tech startup)
• Experience working in a matrixed organization with shared resources across multiple concurrent programs

Your Impact at LILA

Lila Sciences is seeking a relentless executor and strategic operator to spearhead our Instrument Development initiatives and lead our Virtual Lab Team. As the Director of Instrument Development Acceleration, you will be responsible for getting instruments online, fast, reliably, and at scale. The role is for someone who thrives in high-throughput environments and measures success in instruments shipped.

What You'll Be Building

• Set clear expectations, remove obstacles quickly, and keep the team focused on delivery over deliberation.
• Own the rapid design and development of laboratory instruments across the full lifecycle, from concept to operational in the lab, at high volume.
• Architect and implement integration frameworks connecting virtual laboratory environments with physical instrumentation and robotic systems.
• Maintain rigorous hardware-software integration standards, system performance benchmarks, and quality assurance processes without letting them become bottlenecks.
• Make pragmatic technical decisions across software, hardware, and systems integration that keep momentum, escalating only what truly needs escalation.
• Work tightly with AI researchers, software engineers, and robotics teams to drive fast, efficient system integration and deployment.
• Communicate clearly and concisely on status, blockers, and decisions to stakeholders at all levels.
• Build and refine lean development practices that prioritize speed, system reliability, and repeatable quality assurance.

What You’ll Need to Succeed

• Bachelor's or Master's degree in Computer Science, Engineering, Biomedical Engineering, or a related field. Ph.D. is a plus but not required.
• At least 10 years in engineering or technical leadership, with a proven record of delivering complex systems at scale and on time.
• Strong hands-on coding ability in C++, Python, or Java, with deep experience in hardware-software integration.
• Proven ability to lead complex systems integration across software, hardware, and robotic platforms.
• A problem-solver who makes decisions with imperfect information and keeps moving.
• Clear, direct communicator who can align engineers and stakeholders without unnecessary overhead.

Bonus Points For

• Experience with agile or lean development methodologies in high-throughput environments.
• Hands-on knowledge of AI, robotics, and simulation technologies as applied to laboratory instrumentation and automation.
• Experience with system monitoring, performance optimization, and QA in hardware-software environments.
• Track record of scaling teams and processes during periods of rapid growth.

Your Impact at LILA

Lila Sciences is the world’s first scientific superintelligence platform and autonomous lab for life, chemistry, and materials science.  We are pioneering a new age of boundless discovery by building the capabilities to apply AI to every aspect of the scientific method.  We are introducing scientific superintelligence to solve humankind's greatest challenges, enabling scientists to bring forth solutions in human health, climate, and sustainability at a pace and scale never experienced before.

As a Head of Software Product you will serve as the primary architect of our software product strategy. You will lead the development of our “Agentic Superscience” software—the foundational platform designed to reinvent the scientific method through AI. Reporting directly to the Chief Revenue & Product Officer, you will be responsible for transforming complex scientific workflows into a scalable, world-class software ecosystem. You will set the roadmap, build the processes, and the culture necessary to deliver Lila’s most critical competitive advantage. As a member of the leadership team, you will play a critical role in shaping the culture, technical strategy, and therapeutic impact of our software.

What You'll Be Building

• The Agentic Platform: Lead the roadmap and build of our foundational software platform that enables AI agents to conduct, analyze, and iterate on complex materials, chemistry, and biology experiments.
• A Cross-Functional Engine: Create the integrated framework that allows Software, ML, and Wet-lab teams to work in a continuous, high-performance loop.
• Customer-Centric Interfaces: Deliver reliable, intuitive interfaces and high-performance endpoints that make scientific superintelligence accessible to diverse users.
• Operational Excellence: Own the product lifecycle from discovery to delivery. Implement robust frameworks for prioritization that balance rapid innovation with enterprise-grade reliability.
• The Product Org & Executive Voice: You will build the frameworks for high-level communication, serving as the authoritative voice for the software product and providing the strategic insights that will influence Lila’s overall trajectory.

What You’ll Need to Succeed

• 15+ years of experience in Product Management, with a track record of shipping complex, multidisciplinary software systems (0-to-1 and scaling phases) using a modern tech stack.
• Experience building software with AI at its core and must be AI-native.
• Deep understanding of the scientific method, either via schooling in a scientific domain or from experience building software for scientists
• Demonstrated experience building and leading large, high-performing teams in fast-paced, high-stakes environments.
• A drive for impact against mission goals, with a high degree of comfort in the ambiguity of a ‘founding’ environment.
• Capable of communicating technical and scientific concepts to any audience, from engineers to investors.

Bonus Points For

• Experience with automated or self-driving labs.
• Experience building complex agentic AI strategies.

Your Impact at LILA

Lila Sciences is seeking a Principal Software Engineer, Instrument Simulations to architect and lead the development of our next-generation laboratory automation platform. In this role, you'll be responsible for designing the simulation infrastructure and integration layer that connects AI-driven experimental design with physical robotic systems, enabling closed-loop scientific discovery at unprecedented scale.

What You'll Be Building

• Architect and implement high-fidelity simulation environments that model complex laboratory instrumentation, fluidics, and robotic workflows
• Design robust integration patterns between heterogeneous hardware systems, ensuring reliable and safe execution of fully automated experiments
• Lead the development of APIs and interfaces that enable scientists and AI agents to seamlessly interact with sophisticated automation infrastructure
• Maintain and help establish best practices for hardware-software integration, system monitoring, and CI/CD in laboratory automation contexts for all newly developed systems
• Mentor engineers, likely leading a small agile team

What You’ll Need to Succeed

• Bachelor’s or Master’s degree in Computer Science, Engineering, or a related field: Background that supports technical and leadership capabilities.
• 10+ years of software development experience, including 5+ years in a leadership role: Demonstrates ability to lead and manage complex projects and engineering teams.
• Proven experience in architecting and directing large-scale software projects: Skilled in designing and leading the development of scalable, reliable, and maintainable systems.
• Strong proficiency in programming languages such as C++, Python, or Java: Capable of setting technical standards and guiding development practices.
• Strong record of implementing and advocating for engineering best practices such as code reviews, testing, and continuous integration.
• Experience in leading diverse engineering teams with a focus on collaboration, innovation, and efficiency.
• Excellent strategic thinking skills, with the ability to understand and align team efforts with organizational goals.
• Proven ability to mentor and develop engineering talent, fostering an environment of growth and continuous learning.
• Outstanding communication and interpersonal skills: Effectively engage with stakeholders at all levels, from developers to senior executives.

Bonus Points For

• Ph.D. in Computer Science, Engineering, or a related field
• Experience in leading the development of laboratory automation systems or scientific instrumentation
• Experience with organizational change management and fostering innovation in large technical programs.
• Track record of successful project delivery in agile environments, optimizing team workflows and balancing priorities.
• Published work or presentations that highlight contributions to the field of software engineering and leadership in simulation or automation systems.

Your Impact at LILA

As a member of our team in the Physical Sciences division, you will design and build intelligent agent-driven systems that enable AI-accelerated and AI-orchestrated process engineering across a broad range of industrial applications. The core mission of this role is to develop methods by which AI agents can reason about, design, simulate, optimize, and operate complex physical and chemical processes using existing or ML-driven process engineering tools. You will focus on creating agentic infrastructures that allow AI systems to plan and execute multi-step process engineering workflows, ranging from process synthesis and flowsheet generation to steady-state and dynamic simulation, control strategy design, and techno-economic evaluation. Your work will directly shape how Lila’s scientific superintelligence performs closed-loop autonomous process engineering to solve real-world problems.

What You'll Be Building

• Architect and implement agentic frameworks that support end-to-end process engineering workflows, including process setup, simulation, optimization, and analysis.
• Develop AI agents capable of autonomously planning, executing, and iterating on process engineering tasks using existing tools (e.g., steady-state and dynamic simulators, optimizers, and data systems).
• Explore agentic approaches for advanced tasks such as process intensification, control co-design, real-time optimization, and closed-loop learning from operational data.
• Improve robustness, interpretability, and reproducibility of agent-driven process engineering workflows; build internal tooling for debugging, observability, validation, and auditability.
• Work with interdisciplinary teams to apply agentic process engineering to a broad range of industrial applications

What You’ll Need to Succeed

• PhD or equivalent experience in Chemical Engineering, Industrial Engineering, Systems Engineering, or a closely related field.
• Research experience in method development for process engineering, a strong publication record in this area or established industry experience
• Hands-on experience with process simulation and optimization tools (commercial or open-source), including steady-state and dynamic modeling.
• Proficiency in Python and scientific/engineering computing ecosystems
• Experience integrating external engineering tools or simulators into automated workflows via APIs, scripting interfaces, or custom wrappers.
• Familiarity with distributed systems, HPC environments, cloud platforms, or scalable compute infrastructure.

Bonus Points For

• Experience developing or integrating agentic frameworks, autonomous planners, or multi-step tool-using AI systems for engineering or scientific domains.
• Experience building computational pipelines, automation systems, or tool-use frameworks for complex engineering or scientific workflows.
• Experience with digital twins, real-time optimization, or model-predictive control frameworks.
• Background in techno-economic analysis (TEA), life-cycle assessment (LCA), or sustainability-driven process design.
• Contributions to open-source engineering software, ML infrastructure, workflow engines, or agent frameworks.

Your Impact at LILA

As a Scientist on our Physical Sciences team, you will contribute to the development of cutting-edge flow chemistry workflows. You’ll help design, build, and optimize flow chemistry platforms that integrate real-time analytics, advanced control strategies, and AI-driven decision-making. In this role, you’ll work closely with systems engineers and AI scientists to help expand autonomous chemistry capabilities and accelerate discovery at scale. 

What You'll Be Building

• Design & Commission: Architect and develop versatile flow chemistry platforms for autonomous synthesis, ensuring seamless integration with the Lila platform.
• Integrate & Scale: Build, control, and optimize flow reactors and inline analytics. Interface flow chemistry platforms with robotic and sensing systems. 
• Workflow Optimization: Tune flow chemistry platform design and software pipelines for high-throughput closed-loop experimentation with rich metadata capture. 
• Closed-Loop Execution: Collaborate with AI teams to run iterative experiments in real time, enabling fast optimization and discovery cycles.
• Collaboration & Documentation: Work with chemists, material scientists, engineers, and data scientists to document systems, share insights, and refine best practices in autonomous flow chemistry.

What You’ll Need to Succeed

• Ph.D. or M.S. in Chemical Engineering, Chemistry, or a related field. 
• ≥ 1 years (for PhD, 4+ years for M.S ) of hands-on experience in flow chemistry, microfluidics, or microreaction engineering. 
• ≥ 1 years of experience with automation, instrumentation, and integrating real-time analytics into experimental workflows. 
• Strong background in homogeneous chemical catalysis and organic synthesis. 
• Proficiency in Python for scripting, data analysis, and instrument control. 
• Excellent problem-solving, communication, and collaboration skills. 

Bonus Points For 

• Prior experience working in an autonomous or self-driving lab chemical lab environment driving organic chemistry transformations. 
• Familiarity with cloud-based instrumentation control and orchestration.
• Hands-on experience with AI-driven experimental design or Bayesian optimization.
• Background in scaling workflows from proof-of-concept to routine, high-throughput operation.
• Contributions to open-source lab automation or scientific software projects.

Your Impact at LILA

As a member of our team in the Physical Sciences division, you will shape the ML- and agent-driven infrastructure that enables Lila’s scientific superintelligence to autonomously construct, execute, and interpret complex physics simulations. Your work will focus on building the core systems that allow AI agents to reason over and control computational experiments, spanning from electronic structure calculations to surrogate-driven atomistic modeling, and beyond. Your work will directly influence how autonomous computational processes will explore chemical and materials landscapes with unprecedented autonomy and robustness.

What You'll Be Building

• Architect and implement agentic frameworks that support dynamic, multi-stage simulation workflows for scientific tasks
• Develop pipelines enabling agents to autonomously plan, schedule, execute, and interpret computational tasks at scale
• Build integration layers and APIs that connect ML models, large-scale simulation engines, databases, and heterogeneous compute platforms.
• Work with AI researchers to productionize agent behaviors, including tool-use strategies, simulation-aware decision loops, and adaptive task planning.
• Improve the robustness, modularity, performance, and reproducibility of agent-driven computational workflows; build internal tooling for debugging, observability, and validation.

What You’ll Need to Succeed

• MS/PhD or equivalent experience in Computer Science, ML/AI, Scientific Computing, or a related technical field.
• Strong experience building ML-driven pipelines, workflow systems, or tool-use frameworks, ideally for complex or scientific applications.
• Proficiency in Python and ML ecosystems; experience with one or more compiled languages (e.g., C++, Rust, Julia) is beneficial.
• Familiarity with large-scale scientific or engineering software, including integrating external tools into automated computational workflows.
• Experience with distributed systems, HPC environments, cloud platforms, or accelerator-based computing.
• Deep understanding of modern ML architectures and their deployment in production systems (e.g., GNNs, transformers, diffusion models, multimodal or tool-using models).
• Strong engineering fundamentals: reproducibility, testing, modular design, CI/CD, and scalable ML operations.

Bonus Points For

• Experience developing or integrating agentic frameworks, autonomous ML pipelines, or multi-step tool-using agents, particularly for scientific applications
• Background in large-scale simulation frameworks, scientific workflow orchestration, or automated computational experiment platforms.
• Contributions to open-source ML infrastructure, workflow engines, agent frameworks, or scientific software ecosystems.
• Familiarity with data-centric engineering practices: streaming systems, provenance tracking, distributed metadata services, or large-scale data orchestration.
• Experience with workflow orchestration systems (e.g., Flyte, Prefect, Airflow) and container orchestration (Kubernetes).
• Familiarity with materials science simulation codes (VASP, LAMMPS) or workflow frameworks (atomate, aiida) is a plus but not required.
• Expertise in advanced ML techniques relevant to agentic reasoning (planning models, self-improving systems, multi-tool agents, RLHF/RLAIF workflows).

Your Impact at LILA

We’re hiring a Senior Software Engineer to team with our Machine Learning Engineers and Researchers to build software that powers Lila’s ML workflows and research tooling. You will be on a team of software engineers that work alongside machine learning experts to develop, support, and maintain Lila’s ML libraries and tools.

What You’ll Be Building

• Design and build high-performance, secure, and well-documented Machine Learning libraries that implement the algorithms designed by machine learning researchers and engineers.
• CI/CD pipelines and integration tests for ML workflows.
• Architect repository designs to follow consistent standards.
• Support debugging, logging, and maintenance for Ray-based compute environments.
• Data ingestion pipelines linking lab data to ML teams.

What You’ll Need to Succeed

• Minimum of 8 years of experience writing software in a commercial setting in Go or Python.
• Experience implementing scalable software solutions.
• Experience with MLOps systems, GitOps (ArgoCD, Github Actions)
• Familiarity with orchestration frameworks (Ray, Argo, Airflow).
• Proficiency in Containerization, Kubernetes and infrastructure-as-code tools.
• Acute listening skills and patience to deeply understand complex problems and algorithms.
• Excellent problem-solving skills and team-first mentality.
• Energetic self-starter and independent thinker with strong attention to detail.
• Eager to work with highly skilled and dynamic teams in a fast-paced, entrepreneurial, and technical setting.

Bonus Points For

• Proficiency with monitoring and logging tools (e.g., Prometheus, Grafana)
• Research engineering or scientific software experience.

Your Impact at LILA

We are seeking a Senior Software Engineer to join our Applied AI group and help build the next generation of our AI-driven scientific platform. In this role, you will design and optimize the backend systems, data pipelines, and AI integrations that power intelligent, data-driven applications. You’ll work at the intersection of backend engineering and machine learning, ensuring our platform seamlessly scales and supports cutting-edge applied AI techniques such as Retrieval-Augmented Generation (RAG), agentic AI, and large language model (LLM) integration.

This role is ideal for someone who thrives in bridging software engineering and applied AI—turning research into production-grade systems that drive real-world scientific discovery. If you are passionate about building performant, elegant systems that make AI useful and impactful, we would love to hear from you!

What You'll Be Building

• Applied AI Integration: Design and deploy backend services and data pipelines that directly support advanced AI applications, including LLMs, RAG, and agentic frameworks.
• API & Service Development: Build high-performance APIs and microservices that enable seamless integration between AI models, scientific tools, and user-facing applications.
• Data Pipeline Architecture: Architect and manage scalable pipelines capable of handling structured, unstructured, and vectorized data for AI/ML workloads.
• Database & Knowledge Systems: Implement and optimize SQL, NoSQL, and vector databases to support low-latency AI retrieval and inference workloads.
• Cloud & Infrastructure: Leverage AWS, Kubernetes, and infrastructure-as-code (Terraform/CloudFormation) to build robust, production-ready AI platforms.
• Performance & Reliability: Diagnose system bottlenecks, optimize for cost and speed, and ensure the reliability and fault-tolerance of AI-driven workflows.
• Collaboration: Partner with ML researchers, platform engineers, and scientists to translate models and algorithms into scalable, production-ready systems.

What You’ll Need to Succeed

• Educational Background: Bachelor’s or Master’s in Computer Science, Engineering, or a related field.
• Backend & Data Expertise: 7+ years of professional experience building and scaling production systems, including APIs, data pipelines, and distributed services.
• Programming Skills: Strong Python skills (FastAPI, Flask, Django), with solid experience in backend service development.
• Databases: Proven experience with SQL, NoSQL, and vector databases; skilled in schema design, indexing, and query optimization.
• Applied AI Systems: Hands-on experience integrating ML models or AI-driven workflows into production services.
• Cloud & DevOps: Proficiency with AWS, Docker/Kubernetes, CI/CD pipelines, and infrastructure-as-code.
• Communication & Problem-Solving: Ability to work cross-functionally with diverse teams and explain complex technical concepts to non-experts.

Bonus Points For

• Scientific & Data-Intensive Domains: Experience working with life sciences, materials sciences, or other research-heavy fields.
• Startup Experience: Comfort with fast-paced, iterative environments where impact and adaptability matter.

Your Impact at LILA

Lila Sciences is seeking an Industrial Engineer to own and architect the physical layout of our AI Science Factories. In this role, you will be responsible for integrating lab instrumentation and robotics into a cohesive, efficient factory design. You will collaborate closely with hardware engineering, science teams, robotics, facilities, and operations to create layouts that are safe, scalable, and engineered for high-throughput autonomous research. This role is central to translating complex cross-functional requirements into a factory environment that enables Lila’s next-generation scientific capabilities. 

What You'll Be Building

• Own the end-to-end factory layout, including spatial planning, adjacency mapping, and utility requirements
• Integrate lab instrumentation layouts from diverse scientific and engineering domains into a unified, high-performance factory design.
• Collaborate with hardware, robotics, science, automation, safety, and facilities teams to incorporate requirements for utilities, safety, accessibility, maintenance, and environmental controls.
• Build and maintain accurate 2D and 3D CAD models of the full factory layout; drive version control and change management for layout updates.
• Work with robotic teams to run simulations and scenario analyses to assess throughput, operational efficiency, and bottlenecks.
• Partner with construction, facilities, and external vendors to ensure physical buildouts reflect the intended design and can scale with future demand.
• Develop standards, documentation, and layout guidelines for new lab instrumentation and factory expansions.

What You’ll Need to Succeed

• BS/MS degree in Industrial Engineering, Mechanical Engineering, Manufacturing Engineering, Systems Engineering, or related field.
• Experience designing factory, lab, or production layouts in high-complexity environments.
• Proficiency with CAD tools (e.g., AutoCAD, REVIT, SolidWorks).
• Strong understanding of workflow optimization, material flow, ergonomics, and spatial systems.
• Ability to collaborate across multidisciplinary engineering and scientific teams.
• Clear communication and documentation skills.

Bonus Points For

• Experience with robotic or automated systems and their physical integration into facilities.
• Familiarity with lab/industrial utility requirements (HVAC, gases, power, chemicals, drainage).
• Experience in R&D facilities, pilot plants, or advanced automation environments.

Overview:

Description:

Minimum Qualifications:

Education:

•  A minimum of a Bachelor's degree is required.

Flagship Pioneering is a bioplatform innovation company that invents and builds platform companies that change the world. We bring together the greatest scientific minds with entrepreneurial company builders and assemble the capital to allow them to take courageous leaps. Those big leaps in human health and sustainability exponentially accelerate scientific progress in areas ranging from cancer detection and treatment to nature-positive agriculture.   

 What sets Flagship apart is our ability to advance biotechnology by uniting life science innovation, company creation, and capital investment under one roof in a way that is largely without precedent. Our scientific founders, entrepreneurial leaders, and professional capital managers are each aligned around an institutionalized process that enables us to innovate and transform for the benefit of people and planet.   

Many of the companies Flagship has founded have addressed humanity’s most urgent challenges: vaccinating billions of people against COVID-19, curing intractable diseases, improving human health, preempting illness, and feeding the world by improving the resiliency and sustainability of agriculture.  

Flagship has been recognized twice on FORTUNE’s “Change the World” list, an annual ranking of companies that have made a positive social and environmental impact through activities that are part of their core business strategies, and has been twice named to Fast Company’s annual list of the World’s Most Innovative Companies. 

Position Overview: 

Flagship Pioneering is seeking a Senior Manager, HR Operations & Systems to own and evolve our HR systems ecosystem, with primary responsibility for UKG and broad oversight of platforms including Greenhouse and other HR technologies. This role will drive day-to-day administration, governance, integrations, and future-state strategy of HR systems to ensure compliance, enable scalable service delivery, strengthen data integrity, and support a seamless employee experience across the lifecycle. Reporting to the Associate Director, HR Operations & Analytics, this leader will partner closely with HR, Legal, Payroll, Finance, and Enterprise Applications / IT to design system-enabled HR operations that are scalable, well-governed, and built for growth. 

Role Summary 

The Senior Manager, HR Operations & Systems will serve as the business owner for Flagship’s HR systems ecosystem within HR Operations, with primary responsibility for the strategy, administration, optimization, and operational enablement of core HR platforms, including UKG, Greenhouse, and other HR technologies across the employee lifecycle. 

Reporting to the Associate Director, HR Operations & Analytics, this role will partner closely with HR Operations, Talent, Total Rewards, Learning & Culture, Legal, Payroll, Finance, People Analytics, and Enterprise Applications / IT to ensure systems support the HR function in a scalable, compliant, and analytically sound way. 

This leader will help stitch together the HR systems landscape through thoughtful integrations, controls, documentation, and future-state HR tech strategy, while acting as a subject matter expert to IT for implementation and technical design. 

Key Responsibilities 

HR Systems Ownership & Administration 

• Serve as the primary HR business owner for HR systems, with deep ownership of UKG and operational oversight of other HR and talent platforms such as Greenhouse, TalentWall, Crosschq, LinkedIn Recruiter, Pequity, and future tools. 

• Manage day-to-day administration of HR systems, including configuration, permissions, security roles, workflows, testing, issue resolution, release support, and operational documentation. 

• Ensure HR systems are structured and maintained to support scalable service delivery, consistent HR operations, and strong user experience across the employee lifecycle. 

• Maintain system standards, field logic, process flows, and governance documentation to improve consistency and reduce operational ambiguity. 

Systems Architecture, Process Design & Integrations 

• Architect HR systems and processes from an operational perspective, ensuring systems support onboarding, transfers, promotions, offboarding, compliance requirements, and service delivery across the employee lifecycle. 

• Design and optimize integrations across the HR systems landscape, including key connections such as UKG-ADP and Greenhouse-UKG, to improve data flow, reduce manual work, and strengthen downstream reporting and controls. 

• Partner with Enterprise Applications / IT to define technical requirements, integration priorities, testing strategy, and implementation needs; serve as the HR SME for system changes and implementations while IT owns technical implementation and vendor management. 

• Be sufficiently hands-on and technically fluent to configure systems directly where appropriate and to effectively guide or direct technical work when builds are completed by IT or other partners. 

• Identify automation opportunities and future-state improvements across HR systems to improve scalability, reduce friction, and support evolving business needs. 

Compliance, Controls & Governance 

• Partner with HR Operations teammates, Legal, and other stakeholders to ensure systems are designed and configured to enable compliance, controls, audit readiness, and consistent execution of HR processes. 

• Manage system-enabled governance, including permissions, process controls, documentation logic, policy acknowledgement workflows, and audit-supporting records. 

• Help ensure systems support compliance execution across key areas such as documentation completeness, training administration, process controls, and employee record quality. 

• Support the creation of scalable, system-enabled HR ways of working by translating process requirements into governed workflows and operational logic. 

Analytics Enablement & Data Integrity 

• Partner closely with the People Analytics Manager to ensure HR systems are structured to support reliable reporting, meaningful analytics, and consistent data definitions. 

• Improve data integrity across systems by aligning field design, ownership, process inputs, and integrations to reduce discrepancies and improve trust in people data. 

• Ensure systems are built with analytics needs in mind, and conversely, help refine systems based on reporting and data-quality insights. 

• Support the broader HR function in strengthening compliance intelligence, scalable service delivery, and experience optimization through better system design and cleaner data. 

Cross-Functional Partnership & Change Enablement 

• Build strong working relationships across HR, IT, Payroll, Finance, Legal, and other G&A partners to align systems strategy and operational delivery with business needs. 

• Support change enablement through documentation, process clarity, and partnership with HR Operations and other HR team members; formal training delivery is not a core responsibility, but this role will help ensure systems and documentation are set up for successful adoption. 

• Contribute to future-state HR tech strategy, including evaluation of system opportunities and support for upcoming initiatives. 

What Success Looks Like 

• HRIS and the broader HR systems landscape are well-governed, well-documented, and operationally effective. 

• Core employee lifecycle processes are increasingly system-enabled, scalable, and aligned across HR and cross-functional partners. 

• Permissions, controls, and integrations support stronger compliance execution and audit readiness. 

• HR data is consistent, reliable, and usable across all company systems and platforms. 

• The HR team and business partners experience smoother workflows, less manual work, and clearer operational processes. 

• Flagship’s HR tech ecosystem is positioned for future growth, automation, and stronger decision support. 

Qualifications 

• Strong hands-on experience with enterprise HRIS administration and configuration; UKG experience strongly preferred, though deep equivalent HRIS experience may be considered. 

• Experience owning or supporting enterprise HR systems across multiple HR process areas. 

• Experience designing, managing, or supporting integrations between HRIS, ATS, payroll, and other people systems. 

• Strong understanding of how systems support employee lifecycle operations, compliance controls, and scalable service delivery. 

• Experience partnering closely with Enterprise Applications / IT teams on technical requirements, integrations, permissions, and implementation planning. 

• Strong judgment and ability to manage confidential employee and organizational data responsibly. 

• Strong written documentation and process-design skills. 

• Proven track record of independently driving operational improvements and cross-functional initiatives. 

At Flagship, we recognize there is no perfect candidate. If you have some of the experience listed above but not all, please apply anyway. Experience comes in many forms, skills are transferable, and passion goes a long way. We are dedicated to building diverse and inclusive teams and look forward to learning more about your unique background.

Recruitment & Staffing Agencies:  Flagship Pioneering and its affiliated Flagship Lab companies (collectively, “FSP”) do not accept unsolicited resumes from any source other than candidates.  The submission of unsolicited resumes by recruitment or staffing agencies to FSP or its employees is strictly prohibited unless contacted directly by Flagship Pioneering’s internal Talent Acquisition team.   Any resume submitted by an agency in the absence of a signed agreement will automatically become the property of FSP, and FSP will not owe any referral or other fees with respect thereto.

#LI-NM1

The salary range for this role is $128,000 - $176,000. Compensation for the role will depend on a number of factors, including a candidate’s qualifications, skills, competencies, and experience. Flagship Pioneering currently offers healthcare coverage, annual incentive program, retirement benefits and a broad range of other benefits. Compensation and benefits information is based on Flagship Pioneering's good faith estimate as of the date of publication and may be modified in the future.

CMT is seeking a highly skilled and motivated Principal Technical Program Manager to independently lead broad cross-organization efforts from the early stages through release. You will be responsible for coordinating the release activity and assembly for all CMT product lines. Our products are central to our mission, supporting safer drivers and safer roads by integrating seamlessly with a wide range of applications and services. Your leadership will ensure the timely and efficient delivery of our technology to partners and customers, impacting and enhancing safety on a global scale. 

You will be responsible for influencing organization roadmap priorities, system owners, team composition, and technical direction. You will represent difficult trade-off decisions and debates clearly to senior leaders to help them understand options. You will be able to identify when a solution requires additional technical guidance or unlocks powerful capabilities. You will manage cross-functional and cross-organization communication to ensure all stakeholders are informed, and needs are aligned. You will guide the technical direction to deliver solutions that meet CMT’s high standards for customer satisfaction, efficiency, stability, extensibility, simplicity, and operational excellence. 

CMT is looking for a Principal Technical Program Manager I to help us change the world. CMT has helped protect over 65 million drivers and prevent over 126,000 crashes worldwide. We build AI to solve some of the most difficult challenges in mobility — understanding and reducing risk, detecting crashes, and getting people life-saving help. The problems are hard. The impact is real. No matter your role, your work will matter at CMT.

Responsibilities: 

• Experience managing programs across cross functional teams, building processes and coordinating release schedules 
• Strategically lead the planning, scheduling, and execution of project timelines and milestones for CMT product releases, ensuring alignment with company-wide strategic objectives 
• Champion cross-functional collaboration among senior leaders within software engineering, product management, and customer success teams to ensure seamless and efficient release processes at a strategic level 
• Architect and advocate for advanced release management procedures and best practices to enhance efficiency, quality, and scalability of releases across the organization 
• Provide executive-level coordination with internal and external stakeholders to synchronize product release plans with overarching product roadmaps and strategic goals 
• Oversee risk management strategies and resolution processes that affect release scope, schedule, and quality, ensuring robust contingency planning 
• Serve as a primary communication liaison with senior management, external partners, and stakeholders, offering high-level updates, strategic insights, and solutions related to product releases
• Lead compliance and security strategy throughout the release process, ensuring adherence to legal, regulatory, and security requirements at an organizational level 
• Spearhead initiatives to continuously assess, innovate, and enhance the release process, supporting the rapid and safe deployment of new features and updates, while fostering a culture of excellence and continuous improvement
• Complete any additional tasks as they arise 

Qualifications: 

• Bachelor’s degree or equivalent years of experience and/or certification in Computer Science, Engineering, or a related field 
• 7+ years of technical product or program management experience, and experience working directly with engineering teams 
• 5+ years of software development experience 
• 7+ years of hands-on work managing complex technology projects experience
• Expertise in software development lifecycles, agile methodologies, and continuous integration/continuous deployment (CI/CD) processes at a strategic level 
• Exceptional leadership qualities, with the ability to inspire, motivate, and guide senior teams towards achieving strategic objectives 
• Demonstrated ability to operate effectively in a fast-paced, dynamic environment, leading cross-functional senior teams and navigating complex organizational structures
• Advanced experience with mobile technologies and platforms, with a strong understanding of the technical and market dynamics of the mobile ecosystem 
• Strong analytical, strategic thinking, and problem-solving skills, coupled with an intense focus on quality and detail 
• Proven capability to communicate complex technical and strategic concepts to a range of audiences, including executive leadership

Nice to Haves: 

• Master's degree 
• Experience translating customer requirements or contractual commitments into coordinated engineering, product, and delivery plans 
• Experience driving cross-functional programs across machine learning, software engineering, product management, and customer-facing teams 
• Familiarity with ML- or data-driven product development, including model readiness, data dependencies, experimentation, and operational rollout 
• Experience building scalable program governance processes, including intake, prioritization, dependency management, and executive risk reporting 
• Experience delivering complex technical initiatives with external stakeholders, including milestone tracking, status communication, and scope management 
• Experience operating in compliance-, security-, or policy-sensitive technical environments
• Demonstrated success leading distributed teams across time zones and organizational boundaries
• Strong written communication skills for executive updates, customer reviews, and program decision-making

Compensation and Benefits: 

• Fair and competitive salary based on skills and experience, and annual performance bonus 
• Equity may be awarded in the form of Restricted Stock Units (RSUs) 
• Medical, Dental, Vision and Life Insurance, matching 401k, short-term & long-term disability and parental leave 
• Unlimited Paid Time Off including vacation, sick days & public holidays 
• Flexible scheduling and work from home policy depending on role and responsibilities

Base Salary Range

• The base salary range for this position is: $124,000 to $155,000. This range is specifically for Cambridge, MA

Additional Perks:

• Work on a mission with real impact: crashes prevented, injuries avoided, lives protected around the world
• Join an industry leader — 65 million drivers protected, powering 140+ programs across 25 countries
• Be part of the team inventing the future of mobility and road safety
• Move fast, own outcomes, do work that matters
• High ownership, small teams, and direct access to leadership — no layers between your work and its impact
• Unlimited PTO, flexible scheduling, competitive salary, annual performance bonus, RSUs, and full benefits including medical, dental, vision, and 401k match
• Summer Fridays
• Join one of our employee resource groups: Black, AAPI, LGBTQIA+, Women, Book Club, and Health & Wellness
• Comprehensive wellness, education, and employee assistance programs

Commitment to Diversity and Inclusion:

At CMT, we believe the best ideas come from a mix of backgrounds and perspectives. 

We are an equal-opportunity employer committed to creating a workplace and culture where everyone feels valued, respected, and empowered to bring their unique talents and perspectives. Diversity is essential to our success, and we actively seek candidates from all backgrounds to join our growing team. 

We do not discriminate based on race, religion, color, national origin, gender, sexual orientation, age, marital status, veteran status or disability state. CMT is headquartered in Cambridge, MA. To learn more, visit www.cmtelematics.com and follow us on X @cmtelematics.

About Cambridge Mobile Telematics:

Cambridge Mobile Telematics (CMT) is the world’s largest telematics and AI company for safer mobility. Its mission is to make the world’s roads and drivers safer. The company’s AI-driven platform, DriveWell Fusion®, proactively identifies and reduces driving risk, leading to fewer crashes and injuries. To date, CMT’s technology has helped prevent over 126,000 crashes worldwide. CMT enables partners to measure risk, detect crashes, provide life-saving assistance, and streamline claims. Headquartered in Cambridge, MA, CMT operates globally with offices in Budapest, Hungary; Chennai, India; Seattle, Washington; Tokyo, Japan; and Zagreb, Croatia. Learn more at www.cmt.ai.

CMT is looking for a Principal Android Engineer to help us change the world. CMT has helped protect over 65 million drivers and prevent over 126,000 crashes worldwide. We build AI to solve some of the most difficult challenges in mobility — understanding and reducing risk, detecting crashes, and getting people life-saving help. The problems are hard. The impact is real. No matter your role, your work will matter at CMT. This is a principal-level individual contributor role on the Android SDK team, focused on deep technical ownership, cross-functional tech leadership, and driving the architectural direction of CMT's Android SDK platform.

Responsibilities: 

• Partner with product managers to understand business directions and collaborate with product managers, technical leads and other stakeholders to develop project plans that meet business needs
• Own a significant component of the mobile technical stack at CMT 
• Train, guide, and mentor other developers on proper software development procedures and methods
• Participate in the hiring process 
• Cross team and service boundaries to solve technical and business problems
• Design and architect solutions that are maintainable, scalable, reliable and testable while keeping future business directions in mind 
• Lead code and design reviews 
• May lead project groups that are focused on a specific company objective or key result
• Improve company defined development and operational standards and processes
• Provide on-call support during business critical emergency scenarios. Support and troubleshoot production issues as needed. 
• Complete any additional tasks as they arise 

Qualifications: 

• Bachelor’s degree or equivalent years of experience and/or certification in a related field 
• 7+ years of relevant professional experience 
• Ability to do general development tasks on Linux and MacOS; fluency in a scripting language, like Python, Ruby, with the ability to learn more 
• Understanding of Agile development methodologies (specifically SCRUM) 
• Experience with different application architectures such as Model-View-Controller, MVVM, and VIPER
• Experience consuming and/or designing REST APIs 
• Experience building, developing and delivering Android or iOS mobile applications and SDKs
• Basic understanding of end-to-end technical solutions including backend systems
• Experience with continuous deployment, and test-driven development (TDD) 
• Skills required for Android developers: 
• Proficient in both Java and Kotlin with a strong understanding of concurrency concepts
• Experience with Android JetPack libraries 
• Experience with Kotlin coroutines and flows 
• Familiarity with third-party Android libraries like RxJava, Dagger 2, and Retrofit
• Fluency with the Gradle build system for Android 
• Skills required for iOS focused developers:
• Proficient in both Swift and Objective-C with a strong understanding of concurrency concepts
• Experience with iOS Frameworks and development using XCode 
• Familiarity with third-party iOS libraries 
• Fluency with cocoapods or Swift Package Manager

Nice to Haves:

• Actively uses AI coding tools in development work, can critically evaluate AI-generated code for logical errors, edge cases, and security or reliability risks, and can explain and take full ownership of any code incorporated into their work.
• Previous experience developing and maintaining SDKs or mobile platforms consumed by external developers, including managing API versioning, backward compatibility, and developer ergonomics.
• Experience with mobile observability practices, including custom logging pipelines, crash reporting, and metrics collection with low overhead on devices.
• Experience with background processing and battery optimization on Android, including managing OS-level restrictions such as Doze mode, App Standby, and foreground service requirements.
• Demonstrated history of technical leadership without authority, including driving architectural decisions, mentoring peers, and influencing engineering direction across teams.

Compensation and Benefits: 

• Fair and competitive salary based on skills and experience, and annual performance bonus 
• Equity may be awarded in the form of Restricted Stock Units (RSUs) 
• Medical, Dental, Vision and Life Insurance, matching 401k, short-term & long-term disability and parental leave 
• Unlimited Paid Time Off including vacation, sick days & public holidays 
• Flexible scheduling and work from home policy depending on role and responsibilities

Base Salary Range

• The base salary range for this position is: $167,200 to $209,000. This range is specifically for Cambridge, MA

Additional Perks:

• Work on a mission with real impact: crashes prevented, injuries avoided, lives protected around the world
• Join an industry leader — 65 million drivers protected, powering 140+ programs across 25 countries
• Be part of the team inventing the future of mobility and road safety
• Move fast, own outcomes, do work that matters
• High ownership, small teams, and direct access to leadership — no layers between your work and its impact
• Unlimited PTO, flexible scheduling, competitive salary, annual performance bonus, RSUs, and full benefits including medical, dental, vision, and 401k match
• Summer Fridays
• Join one of our employee resource groups: Black, AAPI, LGBTQIA+, Women, Book Club, and Health & Wellness
• Comprehensive wellness, education, and employee assistance programs

Commitment to Diversity and Inclusion:

At CMT, we believe the best ideas come from a mix of backgrounds and perspectives. 

We are an equal-opportunity employer committed to creating a workplace and culture where everyone feels valued, respected, and empowered to bring their unique talents and perspectives. Diversity is essential to our success, and we actively seek candidates from all backgrounds to join our growing team. 

We do not discriminate based on race, religion, color, national origin, gender, sexual orientation, age, marital status, veteran status or disability state. CMT is headquartered in Cambridge, MA. To learn more, visit www.cmtelematics.com and follow us on X @cmtelematics.

About Cambridge Mobile Telematics:

Cambridge Mobile Telematics (CMT) is the world’s largest telematics and AI company for safer mobility. Its mission is to make the world’s roads and drivers safer. The company’s AI-driven platform, DriveWell Fusion®, proactively identifies and reduces driving risk, leading to fewer crashes and injuries. To date, CMT’s technology has helped prevent over 126,000 crashes worldwide. CMT enables partners to measure risk, detect crashes, provide life-saving assistance, and streamline claims. Headquartered in Cambridge, MA, CMT operates globally with offices in Budapest, Hungary; Chennai, India; Seattle, Washington; Tokyo, Japan; and Zagreb, Croatia. Learn more at www.cmt.ai.

Required:

• 3+ in Windows desktop application development using Windows App SDK, WinUI (or similar), C#, XAML — and ideally additional experience with native Windows code (C++, Win32/WinRT/COM).
• Deep understanding of Windows application architecture, including interop between managed code (.NET) and native code.
• Proven track record of designing, building, and shipping production-quality desktop applications, with an emphasis on reliability, performance, scalability, and maintainability.
• Strong experience with accessibility APIs on Windows (e.g. Microsoft UI Automation or similar), and a dedication to building accessible and inclusive software.
• Excellent software engineering fundamentals: OOP, design patterns, data structures, algorithms, memory management, multi-threading or asynchronous programming (where relevant).
• Experience leading technical design, mentoring other engineers, conducting code reviews, and making architecture-level decisions.
• Strong communication skills; ability to articulate tradeoffs, collaborate with cross-functional teams, and drive consensus.
• A user-centric mindset: focus on building polished, intuitive, and accessible experiences for end users.

Preferred / Bonus:

• Experience with writing automated tests for UI — unit tests, integration tests, UI automation tests; familiarity with relevant testing frameworks.
• Experience with performance optimization for desktop apps (memory usage, startup time, rendering performance, high-DPI support, responsiveness under load).
• Experience with localization/globalization, right-to-left UI support, internationalization, accessibility for multiple regions.
• Familiarity with telemetry, analytics, crash reporting, logging, and error monitoring in desktop applications.
• Previous experience in shaping CI/CD workflows, release pipelines, and deployment strategies for desktop applications.
• Demonstrated ability to take ownership of feature areas or modules and drive them long-term, including maintenance, refactoring, and technical debt management.

What we offer

• A high-impact role: you will define architecture, shape the future of our Windows product, and directly influence what millions of users see and experience.
• A collaborative, flat-structure engineering culture — you are not just a coder, but a builder and a decision-maker.
• Opportunities to lead — mentor others, steer technical direction, and grow into broader technical leadership (e.g. Tech Lead, Architect).
• Flexibility, autonomy, and responsibility: you define how to solve problems, own features end-to-end, and contribute to long-term product vision.
• A purpose-driven mission: building software that’s reliable, accessible, and user-centered — making a real difference for people.                  

Think you’re a good fit for this job? 

Tell us more about yourself and why you're interested in the role when you apply.
And don’t forget to include links to your portfolio and LinkedIn.

Not looking but know someone who would make a great fit? 
Refer them! 

Speechify is committed to a diverse and inclusive workplace. 
Speechify does not discriminate on the basis of race, national origin, gender, gender identity, sexual orientation, protected veteran status, disability, age, or other legally protected status.

The Company

Flagship Labs 119 Inc. (FL119) is an early-stage technology company pioneering a new frontier at the intersection of neuroscience and computation. We are developing next-generation technologies to transform how intelligent systems are built. We believe that the future of artificial intelligence demands a fundamental rethinking of today’s paradigms. Our mission is bold and urgent: to build a future where naturalistic, robust intelligence can emerge and operate sustainably at scale.

FL119 is backed by Flagship Pioneering, which brings the courage, long-term vision, and resources needed to realize unreasonable results. At FL119, we are uniquely cross-functional and collaborative. Our teams thrive in unstructured and creative environments. All voices are heard because we know that experience comes in many forms, skills are transferable, and passion goes a long way.

The Role:

FL119 is seeking a creative and deeply technical Neuromorphic Systems Architect to join our team. Leveling is flexible based on experience.

This role will focus on translating nonlinear neural dynamics into next-generation computational architectures. You will work at the interface of neuroscience, dynamical systems theory, and hardware engineering to design and prototype electronic architectures that embody biologically derived principles of computation.

This is not a conventional AI accelerator role. We are seeking someone who can rethink compute from first principles, designing architectures that leverage recurrence, nonlinearity, sparsity, event-driven signaling, and adaptive dynamics as foundational primitives rather than constraints.

How You Will Contribute:

• Formalize brain-derived computation using dynamical systems theory and translate these insights into hardware-relevant abstractions.
• Architect novel neuromorphic or neuro-inspired hardware systems (analog, mixed-signal, in-memory, or alternative substrates).
• Define system-level architecture, including memory models, communication schemes, and energy-efficient compute primitives.
• Collaborate with neuroscience, signal processing, and machine learning teams to ensure tight coupling between biological insight and architectural design.
• Lead feasibility studies, simulations, and early-stage prototyping efforts.
• Evaluate trade-offs across CMOS, emerging devices, photonic, memristive, or other unconventional compute substrates.
• Contribute to IP strategy, including invention disclosures and patents.
• Help shape the long-term compute vision of the company.

Must-have Qualifications:

• PhD (or equivalent experience) in Electrical Engineering, Applied Physics, Computational Neuroscience, Computer Engineering, or a closely related field.
• Deep expertise in nonlinear dynamical systems and their application to computation.
• Experience designing hardware architectures (ASIC, FPGA, analog/mixed-signal, or emerging device technologies such as RRAM, PCM, memristors, etc.).
• Strong mathematical foundation in dynamical systems, control theory, or computational modeling.
• Demonstrated ability to move from theory to implementable system design.
• 5+ years of relevant research or industry experience (level dependent)

Preferred Experience:

• Prior work in neuromorphic computing or spiking neural network hardware.
• Experience with event-driven or asynchronous architectures.
• Familiarity with reservoir computing, recurrent dynamical systems, or physical computing substrates.
• Experience working in early-stage, fast-paced R&D environments.
• Track record of patents or high-impact publications in neuromorphic systems or unconventional computing.

ABOUT FLAGSHIP PIONEERING

Flagship Pioneering invents and builds platform companies, each with the potential for multiple products that transform human health, sustainability and beyond. Since its launch in 2000, Flagship has originated more than 100 companies. Many of these companies have addressed humanity’s most urgent challenges: vaccinating billions of people against COVID-19, curing intractable diseases, improving human health, preempting illness, and feeding the world by improving the resiliency and sustainability of agriculture.  

Flagship has been recognized twice on FORTUNE’s “Change the World” list, an annual ranking of companies that have made a positive social and environmental impact through activities that are part of their core business strategies and has been twice named to Fast Company’s annual list of the World’s Most Innovative Companies. Learn more about Flagship at www.flagshippioneering.com.

At Flagship, we accept impossible missions to enable bigger leaps. Our core values guide us through uncertainty and toward lasting impact.

We are an equal opportunity employer. All qualified applicants will be considered for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, disability, protected veteran status, or any other characteristic protected by law.

We recognize that great candidates often bring unique strengths without fulfilling every qualification. If you have some of the experience listed above but not all, please apply anyway. We are dedicated to building diverse and inclusive teams and look forward to learning more about your background and interest in Flagship.

Recruitment & Staffing Agencies: Flagship Pioneering and its affiliated Flagship Lab companies (collectively, “FSP”) do not accept unsolicited resumes from any source other than candidates. The submission of unsolicited resumes by recruitment or staffing agencies to FSP or its employees is strictly prohibited unless contacted directly by Flagship Pioneering’s internal Talent Acquisition team. Any resume submitted by an agency in the absence of a signed agreement will automatically become the property of FSP, and FSP will not owe any referral or other fees with respect thereto.

#LI-MB1

The salary range for this role is $150,000 - $250,000. Compensation for the role will depend on a number of factors, including a candidate’s qualifications, skills, competencies, and experience. FL119 currently offers healthcare coverage, annual incentive program, retirement benefits and a broad range of other benefits. Compensation and benefits information is based on FL119's good faith estimate as of the date of publication and may be modified in the future.

COMPANY DESCRIPTION

Extuitive is a Flagship Pioneering–backed startup reimagining product innovation for the AI era. Our mission is to empower entrepreneurs and direct-to-consumer (D2C) brands with AI-driven tools that simplify, accelerate, and scale the launch of new products. Based in Cambridge, MA, we operate like a special ops unit—fast-moving, data-driven, and relentlessly focused on impact.

THE ROLE

As a Principal Backend Engineer, you’ll be a technical leader responsible for architecting, building, and scaling the core backend systems that power our platform. You’ll drive the design of high-throughput services, resilient data pipelines, and integrations with mission-critical third-party providers. Working closely with product managers, designers, and engineering leadership, you’ll translate complex requirements into robust, elegant systems that support rapid growth. You’ll mentor engineers, influence long-term technical strategy, and help evolve our platform architecture to maintain security and reliability as we scale.

KEY RESPONSIBILITIES

• Own Core Backend Systems – Design, build, and maintain scalable services, APIs, and platform infrastructure. Ensure reliability, observability, and maintainability.
• Drive Large-Scale Data Pipelines – Architect and operate high-volume, resilient data pipelines for ingestion, transformation, and analytics.
• Lead Third-Party Integrations – Build and maintain integrations with external vendors, ensuring reliability, observability, and long-term maintainability.
• Influence Architecture & Best Practices – Shape backend architecture, coding standards, testing frameworks, CI/CD pipelines, and operational excellence.
• Mentor & Lead Engineers – Provide guidance on system design, debugging at scale, and engineering practices.
• Wear Multiple Hats – Support DevOps, troubleshooting, or other platform needs when necessary.

PROFESSIONAL EXPERIENCE & QUALIFICATIONS 

• 8+ years of backend engineering experience.
• Bachelor’s degree in Computer Science, Software Engineering, or equivalent practical experience.
• Strong expertise in backend languages and frameworks (Node.js/TypeScript, Go, Python, or similar).
• Experience designing scalable distributed systems, microservices, and event-driven architectures.
• Deep experience with third-party integrations, REST/GraphQL APIs, webhooks, and rate-limited services.
• Proficiency with SQL/NoSQL databases, data pipelines, and performance optimization.
• Familiarity with cloud platforms (AWS, GCP) and containerized/deployed systems (Docker, Kubernetes).
• Strong testing, CI/CD, and observability practices.
• Comfortable working in a fast-paced, evolving environment with minimal oversight.

Nice to Have 

• Experience building and shipping features quickly in early-stage startups.
• Exposure to multiple backend domains (analytics, payments, notifications, workflow orchestration).
• Hands-on experience with serverless or edge architectures for rapid iteration.
• Familiarity with low-friction integrations with third-party tools and SaaS platforms.
• Track record of scaling systems from small MVPs to production-ready services.
• Comfort with ambiguity and making trade-offs between speed, quality, and maintainability.

ABOUT FLAGSHIP PIONEERING:

Flagship Pioneering invents and builds platform companies, each with the potential for multiple products that transform human health, sustainability and beyond. Since its launch in 2000, Flagship has originated more than 100 companies. Many of these companies have addressed humanity’s most urgent challenges: vaccinating billions of people against COVID-19, curing intractable diseases, improving human health, preempting illness, and feeding the world by improving the resiliency and sustainability of agriculture.  

Flagship has been recognized twice on FORTUNE’s “Change the World” list, an annual ranking of companies that have made a positive social and environmental impact through activities that are part of their core business strategies and has been twice named to Fast Company’s annual list of the World’s Most Innovative Companies. Learn more about Flagship at www.flagshippioneering.com.

At Flagship, we accept impossible missions to enable bigger leaps. Our core values guide us through uncertainty and toward lasting impact.

We are an equal opportunity employer. All qualified applicants will be considered for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, disability, protected veteran status, or any other characteristic protected by law.

We recognize that great candidates often bring unique strengths without fulfilling every qualification. If you have some of the experience listed above but not all, please apply anyway. We are dedicated to building diverse and inclusive teams and look forward to learning more about your background and interest in Flagship.

Recruitment & Staffing Agencies: Flagship Pioneering and its affiliated Flagship Lab companies (collectively, “FSP”) do not accept unsolicited resumes from any source other than candidates. The submission of unsolicited resumes by recruitment or staffing agencies to FSP or its employees is strictly prohibited unless contacted directly by Flagship Pioneering’s internal Talent Acquisition team. Any resume submitted by an agency in the absence of a signed agreement will automatically become the property of FSP, and FSP will not owe any referral or other fees with respect thereto.

The salary range for this role is $152,000 - $209,000. Compensation for the role will depend on a number of factors, including a candidate’s qualifications, skills, competencies, and experience. Extuitive, Inc. currently offers healthcare coverage, annual incentive program, retirement benefits and a broad range of other benefits. Compensation and benefits information is based on Extuitive, Inc.'s good faith estimate as of the date of publication and may be modified in the future.

ABOUT PIONEERING INTELLIGENCE

Pioneering Intelligence builds on Flagship Pioneering’s legacy of founding cutting-edge science and computational ventures, harnessing recent advances in AI, machine learning, and data to accelerate fundamental research and create a portfolio of AI-first companies. As part of Flagship’s integrated model of science, entrepreneurship, and capital, it transforms breakthrough ideas into world-changing companies, elevating the AI advances happening across the ecosystem in human health, sustainability, and beyond.

Position Summary 

We are seeking a Senior Front End Engineer. As a key contributor in this early-stage initiative, you will architect and implement the user experience for a new platform that leverages large language models (LLMs) and AI agents to enhance complex, high-stakes workflows. This is a user-first, AI-augmented product — your work will transform abstract reasoning tasks into intuitive, high-performance tools that empower experts across diverse research domains. You will lead front-end development and collaborate closely with engineers, AI scientists, product designers, and end users. This is a rare opportunity to shape a greenfield product at the intersection of usability, flexibility, and advanced reasoning. 

Key Responsibilities 

• Architect, develop, and maintain high-quality, testable front-end code and workflows aligned with complex scientific and analytical use cases. 
• Translate user stories, wireframes, and prototypes into production-ready features emphasizing clarity, maintainability, and reusability. 
• Implement responsive, accessible, and performant UIs optimized for data-rich, interactive workflows. 
• Ensure security, scalability, and observability of front-end services in cloud environments (AWS). 
• Design and implement user interfaces from scratch, combining strong visual design with robust engineering. 
• Create and maintain scalable, consistent, and visually appealing UI components using a modern React.js stack. 
• Maintain front-end quality through comprehensive testing and validation of user flows and interface behavior. 
• Develop and maintain test suites (unit, integration, and end-to-end) for UI reliability. 
• Apply DevOps/GitOps practices for automated testing, deployment, and monitoring. 
• Mentor engineers and scientists, driving technical quality and ensuring extensibility and performance across evolving use cases. 

Qualifications 

• B.S. in Computer Science, Engineering, or related field, with 6+ years of professional software development experience. 
• Expertise with modern front-end frameworks and tools, including React.js, TypeScript, Tailwind CSS, Redux Toolkit, Playwright, and Shadcn. 
• Strong experience with Node.js. 
• Skilled in writing and maintaining comprehensive test suites (Jest, React Testing Library, Cypress). 
• Experience with system design, performance optimization, observability, and operational excellence for parallel LLM workloads. 
• Strong intuition for UX design and a passion for building intuitive, workflow-first products. 
• Excellent communication skills and a collaborative mindset in fast-moving, cross-functional environments. 

Preferred Qualifications 

• Background in scientific domains such as biology, chemistry, or complex systems (a plus, not required). 

Why Join Us 

By joining this initiative within Flagship’s Pioneering Intelligence group, you will: 

• Help define a new category of intelligent software tools for real-time human–AI collaboration. 
• Build a greenfield product at the intersection of usability, reasoning, and scientific innovation. 
• Collaborate with visionary thinkers and top-tier researchers across Flagship’s ecosystem. 
• Thrive in a supportive, mission-driven culture with access to world-class technical and operational resources. 
• Shape the future of AI-powered discovery in a role that combines engineering excellence with health impact. 

About Flagship Pioneering

Flagship Pioneering invents and builds platform companies, each with the potential for multiple products that transform human health, sustainability and beyond. Since its launch in 2000, Flagship has originated more than 100 companies. Many of these companies have addressed humanity’s most urgent challenges: vaccinating billions of people against COVID-19, curing intractable diseases, improving human health, preempting illness, and feeding the world by improving the resiliency and sustainability of agriculture.  

Flagship has been recognized twice on FORTUNE’s “Change the World” list, an annual ranking of companies that have made a positive social and environmental impact through activities that are part of their core business strategies and has been twice named to Fast Company’s annual list of the World’s Most Innovative Companies. Learn more about Flagship at www.flagshippioneering.com.

At Flagship, we accept impossible missions to enable bigger leaps. Our core values guide us through uncertainty and toward lasting impact.

We are an equal opportunity employer. All qualified applicants will be considered for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, disability, protected veteran status, or any other characteristic protected by law.

We recognize that great candidates often bring unique strengths without fulfilling every qualification. If you have some of the experience listed above but not all, please apply anyway. We are dedicated to building diverse and inclusive teams and look forward to learning more about your background and interest in Flagship.

Recruitment & Staffing Agencies: Flagship Pioneering and its affiliated Flagship Lab companies (collectively, “FSP”) do not accept unsolicited resumes from any source other than candidates. The submission of unsolicited resumes by recruitment or staffing agencies to FSP or its employees is strictly prohibited unless contacted directly by Flagship Pioneering’s internal Talent Acquisition team. Any resume submitted by an agency in the absence of a signed agreement will automatically become the property of FSP, and FSP will not owe any referral or other fees with respect thereto.

#LI-MB1

The salary range for this role is $108,000 - $176,000. Compensation for the role will depend on a number of factors, including a candidate’s qualifications, skills, competencies, and experience. Pioneering Intelligence currently offers healthcare coverage, annual incentive program, retirement benefits and a broad range of other benefits. Compensation and benefits information is based on Pioneering Intelligence's good faith estimate as of the date of publication and may be modified in the future.

ABOUT PIONEERING INTELLIGENCE

Pioneering Intelligence builds on Flagship Pioneering’s legacy of founding cutting-edge science and computational ventures, harnessing recent advances in AI, machine learning, and data to accelerate fundamental research and create a portfolio of AI-first companies. As part of Flagship’s integrated model of science, entrepreneurship, and capital, it transforms breakthrough ideas into world-changing companies, elevating the AI advances happening across the ecosystem in human health, sustainability, and beyond.

THE ROLE

The Pioneering Intelligence team at Flagship Pioneering builds the digital and AI foundation that accelerates the creation and growth our companies. We are seeking a Senior Vice President (SVP) – AI & Digital Platform to enable AI tooling across our enterprise, shepherd our AI-native data platform, maintain and evolve the digital backbone of our early stage companies, and lead a world-class technology team though support, empowerment, and accountability. This is a senior leadership role within the Pioneering Intelligence Initiative, offering the opportunity to shape the strategy, execution, and impact of AI across Flagship’s ecosystem. 

As the SVP – AI & Digital Platform, you will be responsible for defining and executing the vision for how AI and digital technologies enable Flagship and its portfolio companies. You will shepherd and deliver the platforms, tools, and infrastructure that power AI-native operations and empower scientific and business teams. This role combines strategic leadership with deep technical expertise, requiring you to operate in highly ambiguous environments, shape long-term direction, and build organizational capabilities that endure. 

KEY RESPONSIBILITIES

• Enable AI tooling and capabilities across scientific and operational workflows.
• Architect and implement an AI-native data platform that empowers Agentic AI and AI Modeling teams.
• Maintain and evolve the PI Digital Backbone—Flagship’s shared infrastructure “starter kit” for new company launches, including compute, shared code, and AI tools.
• Support and develop a high-performing, product-minded technology organization.
• Partner with portfolio company founders, venture teams, scientific leaders, and functional teams to align and drive adoption of our shared digital strategy.
• Develop and communicate strategy for Flagship’s AI initiatives internally and externally. 

PROFESSIONAL EXPERIENCE & QUALIFICATIONS 

• 15+ years of progressive leadership experience in AI, data platforms, or digital technology, ideally spanning both technology and life sciences.
• Demonstrated success in building and scaling platforms that deliver measurable scientific or business outcomes.
• Deep expertise in AI, ML, and data architectures, paired with strong product and business acumen.
• Proven ability to thrive in highly ambiguous, rapidly evolving environments.
• Track record of building and leading diverse, high-performing teams.
• Excellent communication and collaboration skills, with the ability to influence at all levels of an organization. 

Preferred Qualifications 

• Experience creating or scaling digital platforms in complex or scientific domains.
• Familiarity with life sciences R&D workflows and the opportunities for AI-driven acceleration.
• Experience with early-stage B2B software product development.
• Strong network within the AI and digital innovation ecosystem. 

WHY PIONEERING INTELLIGENCE? 

• Lead a bold initiative at the intersection of AI, digital platforms, and pioneering science.
• Help define the future of Flagship’s digital and AI strategy, impacting multiple portfolio companies.
• Collaborate with visionary founders, scientists, and innovators across Flagship’s ecosystem.
• Build in a supportive, mission-driven culture with access to world-class technical and operational resources.
• Competitive compensation and benefits, including equity, commensurate with experience. 

ABOUT FLAGSHIP PIONEERING

Flagship Pioneering invents and builds platform companies, each with the potential for multiple products that transform human health, sustainability and beyond. Since its launch in 2000, Flagship has originated more than 100 companies. Many of these companies have addressed humanity’s most urgent challenges: vaccinating billions of people against COVID-19, curing intractable diseases, improving human health, preempting illness, and feeding the world by improving the resiliency and sustainability of agriculture.  

Flagship has been recognized twice on FORTUNE’s “Change the World” list, an annual ranking of companies that have made a positive social and environmental impact through activities that are part of their core business strategies and has been twice named to Fast Company’s annual list of the World’s Most Innovative Companies. Learn more about Flagship at www.flagshippioneering.com.

At Flagship, we accept impossible missions to enable bigger leaps. Our core values guide us through uncertainty and toward lasting impact.

We are an equal opportunity employer. All qualified applicants will be considered for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, disability, protected veteran status, or any other characteristic protected by law.

We recognize that great candidates often bring unique strengths without fulfilling every qualification. If you have some of the experience listed above but not all, please apply anyway. We are dedicated to building diverse and inclusive teams and look forward to learning more about your background and interest in Flagship.

Recruitment & Staffing Agencies: Flagship Pioneering and its affiliated Flagship Lab companies (collectively, “FSP”) do not accept unsolicited resumes from any source other than candidates. The submission of unsolicited resumes by recruitment or staffing agencies to FSP or its employees is strictly prohibited unless contacted directly by Flagship Pioneering’s internal Talent Acquisition team. Any resume submitted by an agency in the absence of a signed agreement will automatically become the property of FSP, and FSP will not owe any referral or other fees with respect thereto.

 #LI-NM1

The salary range for this role is $325,000 - $450,000. Compensation for the role will depend on a number of factors, including a candidate’s qualifications, skills, competencies, and experience. Pioneering Intelligence currently offers healthcare coverage, annual incentive program, retirement benefits and a broad range of other benefits. Compensation and benefits information is based on Pioneering Intelligence's good faith estimate as of the date of publication and may be modified in the future.

About the Team

At Roku, the UI team builds the foundational frameworks, tooling, and high-performance UI components that power experiences across millions of devices. We own the middleware and UI layers that enable smooth navigation, responsive interactions, rich animations, and consistent developer workflows across the platform.

Our work spans graphics rendering, layout and animation systems, performance optimization, and developer APIs that make it easy to create reliable, visually compelling applications at scale. We operate in a collaborative, high-trust environment and partner closely with firmware, platform, and product teams to ensure the end-to-end experience is fast, robust, and future-ready.

About the Role

As a Senior Software Engineer on the UI team, you’ll design, implement, and optimize systems that underpin Roku’s user experience and developer platform. You’ll work on performance-critical code paths across graphics rendering, animation, layout, and UI frameworks, ensuring smooth visuals and highly responsive interactions across a wide range of devices.

You’ll play a key role in shaping core architecture, working across the stack with hardware, firmware, and application teams, and delivering solutions that directly impact tens of millions of users. This role is ideal for engineers who enjoy deep technical problem-solving, care about performance at a systems level, and want to build the foundational layers that power great user experiences.

What You’ll Be Doing

• Build and scale UI frameworks and features optimized for millions of users
• Design and implement performance-critical systems across rendering pipelines, layout engines, and animation frameworks using C++
• Develop and maintain developer-facing tools and UI layers 
• Lead technical investigations and architect solutions across middleware and UI infrastructure
• Integrate AI/ML capabilities into developer workflows and platform features, leveraging generative AI to improve productivity and user experience
• Collaborate with cross-functional teams to deliver platform features with measurable gains in performance, reliability, and scalability
• Create tooling, frameworks, and automation that improve developer efficiency and code quality
• Mentor junior engineers through design reviews, pair programming, and technical guidance
• Stay current with advancements in graphics, UI systems, and AI, and proactively identify opportunities for improvement

We’re Excited If You Have

• 6+ years of software engineering experience with a strong focus on UI frameworks, systems, or application development
• Strong proficiency in C++ for performance-critical systems and rendering pipelines
• Strong proficiency in TypeScript for 
• Experience with Javascript/BrightScript or similar scripting languages
• Proficiency in Python for tooling, automation, or AI workflows
• Hands-on experience integrating AI/ML and generative AI tools into development workflows or product features
• Solid understanding of graphics systems, rendering, or UI performance optimization
• Strong debugging and root cause analysis skills
• Clear and effective technical communication skills
• A proactive mindset with a focus on continuous learning, fast iteration, and data-driven decision making

#LI-NM1

The Opportunity

The Senior Director, Trade & Channel Operations will be responsible for building Amylyx’s U.S. distribution and channel model from the ground up in preparation for a future commercial launch of our lead product candidate. This individual will architect the distribution strategy, create the operational infrastructure necessary for launch, and partner cross functionally to ensure Amylyx is fully prepared to commercialize with excellence. As a key member of the Market Access team, this role will influence launch readiness, customer service delivery, and ongoing performance across distribution partners.

Responsibilities

• Design and build Amylyx’s U.S. distribution model across specialty pharmacy, specialty distributor, and 3PL channels to support product launch
• Lead contracting strategy for specialty pharmacies and distributors, including negotiating distribution and service agreements, fee schedules, data requirements, and service levels
• Integrate distribution channels with service programs and field initiatives to enable a seamless customer experience
• Collaborate with Supply Chain and Finance to support 3PL operations, including order‑to‑cash processes, inventory management, data exchange, shipping, returns, and chargeback management
• Establish and manage noncommercial and free‑goods pharmacy operations
• Forecast and model channel performance, assess specialty pharmacy throughput, and provide recommendations to ensure timely, reliable patient access
• Develop distribution analytics including inventory visibility, service metrics, dispense data, time to therapy, and partner scorecards; lead specialty pharmacy QBRs
• Partner cross‑functionally with Supply Chain, Quality, Compliance, Legal, Finance, Patient Services, and Commercial Operations to ensure operational alignment and launch readiness
• Serve as a senior leader within Market Access, contributing to launch planning, forecasting, patient access workflows, and overall distribution strategy
• Continuously optimize post‑launch distribution operations by driving root‑cause remediation, vendor KPI management, and process improvements informed by field and service feedback.

Required Qualifications

• Bachelor’s degree required
• 12+ years of experience in biopharmaceutical trade and distribution, including leadership of specialty pharmacy and distributor channel networks
• Prior product launch experience in the US market
• Experience designing and implementing channel strategies for product launches
• Proven ability to assess, manage, and influence channel partner performance to contractual expectations
• Hands‑on experience with 3PL operations, serialization, state licensing, and compliant distribution processes
• Demonstrated strength in contract negotiation, vendor management, and commercial channel operations
• Deep understanding of payer reimbursement, hub/patient support integration, channel economics, and order‑to‑cash workflows
• Proven leadership experience, including managing large pharmaceutical vendors, with demonstrated people management skills
• Excellent communication, vendor management, analytical, and project execution capabilities

Work Location and Conditions

• At Amylyx, we proudly support remote work opportunities within the United States. However, due to business considerations related to health insurance coverage and state tax regulations, we are unable to hire employees who reside and/or work in certain states. Currently, we are not considering applicants from Alaska, Arizona, Hawaii Michigan and Tennessee.
• You will be expected to travel to our corporate location in Cambridge, MA several times a year and attend other company-related events as necessary and requested.
• You must have access to work in setting which enables meeting all requirements of the role (including privacy, reliable internet access, phone, ability to video conference, etc.) at your remote location.

Philo: a streaming service for TV and movie lovers

At Philo, we’re a group of technology and product people who set out to build the future of television, marrying the best in modern technology with the most compelling medium ever invented — in short, we’re building the TV experience that we’ve always wanted for ourselves. In practice this means leveraging cloud delivery, modern tech stacks, machine learning, and hand-crafted native app experiences on all of our platforms. We aim to deliver a rock solid experience on the streaming basics, while cooking up next generation multi-screen and multi-user playback experiences.

Data at Philo

Data underpins everything we do at Philo: making informed business decisions; analyzing and improving the quality of our streaming experience; running product experiments to optimize our signup flows and improve user journeys; and making it effortless for our users to find the perfect thing to watch. Philo serves over a billion streams to its users every year, generating a wealth of data that we leverage at all levels of the organization. Philo’s data platform operates at very large scale, processing trillions of events annually in a petabyte-scale data lake and supporting thousands of data workflows and analytical queries that power decision-making across the company.

Philo’s Data Engineering team encompasses both data engineering and analytics engineering, and we’re looking for people who are comfortable working on complex data infrastructure and modeling challenges that support critical business functions across our streaming services. You’ll be working closely with other data scientists, analysts, and engineers to build and deploy solutions directly for our service – this work spans both foundational data platform work like data warehouse architecture, metric governance, and semantic consistency across our entire data stack. In addition, you’ll work with departments across the organization to understand their data needs and deliver high-performance, reliable data systems to help the entire team thrive.

We are passionate about building robust, scalable data infrastructure and providing a high-quality data platform for the entire company, using both cutting-edge technologies and proven engineering practices in close collaboration with every department. To complete our work, we build on modern tools including AWS-native services, dbt, Segment, Snowflake, AWS SageMaker, Spark, Avo, BigEye and more.

Some of the recent projects that data and analytics engineers at Philo have worked on include building new models for key financial data, dbt model design, data warehouse cluster upgrades and maintenance, per-query infra cost optimization, implementation of Apache Iceberg data storage, benchmarking & improving data warehouse performance, and evaluating alternative data warehouse technologies.

The Role

We're seeking a senior technical and foundational leader to own and drive the vision, strategy, and execution of our Data Engineering team, encompassing both the data engineering and analytics engineering  functions at Philo. This is a strategic and high-impact role: you'll set the long-term direction for our entire data platform, lead and grow a team of data and analytics engineers, and roll up your sleeves to architect and build alongside them. The ideal candidate has owned both disciplines before — data infrastructure and analytics engineering — and brings strong opinions on how to structure a high-velocity, high-trust data organization. 

Responsibilities:

• Own the vision and technical strategy for data engineering and analytics engineering at Philo, setting the direction for how data is ingested, modeled, and delivered across the organization
• Own the team’s roadmap, balancing strategic long-term investments with near-term stakeholder needs
• Lead and grow the Data Engineering team, including hiring, career development, performance management, and supporting the team in generally thriving
• Lead the design and implementation of Philo's data platform architecture, including  setting technical standards and best practices for data engineering and analytics engineering work
• Collaborate with cross-functional teams to understand data platform needs and translate business requirements into technical solutions
• Build and maintain stakeholder trust in data and reporting — ensuring that business teams have reliable, well-documented, and well-understood data products
• Design scalable data pipelines and infrastructure; drive technical decisions with a focus on long-term sustainability
• Implement data governance, security, and quality control processes as needed
• Ultimately, deliver on the alchemy of transforming raw, messy application data into trusted business insight through scalable dimensional modeling and a metric layer that faithfully reflects product and customer behavior.

Key Qualifications:

• 10+ years of professional experience spanning data engineering and analytics engineering, ideally with a few years working on high-volume data platforms
• 4+ years of experience managing and leading data teams, with demonstrated experience owning both data engineering and analytics engineering functions at a prior organization
• Deep expertise in modern data stack technologies, particularly AWS data services, Snowflake, dbt, Airflow, Airbyte, Python, and SQL
• Deep expertise in analytics engineering, including dbt model design, dimensional modeling, and delivering trusted, business-facing data products
• Strong people management skills with experience providing coaching, performance feedback, and career development guidance to direct reports.
• Track record of improving stakeholder trust in reporting and data quality across an organization
• Strong track record of designing and implementing data platforms
• Excellent communication skills with technical and non-technical stakeholders, simplifying complex data concepts for various business audiences

Ideal Qualifications:

• Experience in media/streaming industry with understanding of video delivery analytics and metrics
• Demonstrated experience driving organizational alignment around data definitions, metrics, and a single source of truth
• Experience with data governance and compliance requirements
• Background in implementing data quality frameworks

More about Philo

At Philo, we’re a company that puts people first—both our subscribers and our team. We empower our colleagues to do their best work while supporting one another in pursuing shared goals. We value pragmatism, pride in our work, and passion, with transparency and openness as fundamental parts of our culture.

We’re committed to diversity, equity, inclusion, and accessibility as we grow the Philo team and shape the future of TV. We believe that a diverse range of voices and perspectives enables us to innovate faster and create the best experiences for our subscribers. Philo is proud to be an Equal Opportunity Employer. We’re committed to supporting every candidate and employee. If you need an accommodation at any stage of the process, please email recruiting@philo.com and we’ll work with you to meet your needs.

Philo offers 70+ top-rated networks streaming live and on-demand, including AMC, BET, CMT, Comedy Central, Discovery Channel, Food Network, Hallmark Channel, HGTV, HISTORY, Investigation Discovery, Lifetime, MTV, Nickelodeon, OWN, VH1, We TV, and more. It also includes all the groundbreaking originals and blockbuster movies available with AMC+ and access to HBO Max Basic With Ads and discovery+. Our service also includes 100+ free channels and premium add-ons like STARZ and MGM+.

Our extensive library boasts over 85,000 titles, and our unlimited DVR allows users to save their favorite shows and movies for up to a year, skipping ads for a seamless viewing experience. Stream on up to three devices simultaneously, whether on your phone, tablet, laptop, or TV using Roku, Apple TV, Fire TV, Samsung TV, Android TV, Vizio TV, or Chromecast.

Philo is headquartered in San Francisco, with offices in New York City and Cambridge, MA. Our leadership team includes alums from HBO, Tubi, and Meraki, and is backed by NEA and industry partners like Warner Brothers Discovery, Viacom, AMC, and A&E.

Join us at Philo and be part of a team that's shaping the future of TV!

Status: Full-time
Location: San Francisco, CA, Brooklyn, NY, Cambridge, MA, or remote within the U.S.
Compensation: Includes annual salary, company stock options, and health benefits. Salary is determined by experience and location:

• San Francisco, New York City: $240K - $275K
• Boston, DC Metro, Los Angeles, Seattle: $225K - $260K
• Denver, Atlanta, Austin, Las Vegas, Sacramento, Chicago: $215K - $250K
• Texas, Florida: $200K - $235K

We value a diverse and inclusive workplace and we welcome people of different backgrounds, experiences, skills, and perspectives. Philo is an equal opportunity employer. We believe that everyone does their best work when they are supported by each other and the company, and we offer a generous set of benefits to make sure the Philo team is happy and healthy. Here is a sampling of the benefits we offer our team:

• Full health, dental and vision coverage for you and your family
• 401(k) plan with employer contributions (we match 100% of deferrals up to 3% of pay and 50% of the next 2% of pay)
• Flexible working hours
• Up to 20 weeks of fully paid parental leave
• Unlimited paid time off for vacation and sick leave
• $2,000 annual vacation bonus (we pay you to take a two week vacation)
• $5,250 annually for professional development and educational assistance
• $1,250 annual home office + TV stipend during first year of employment ($250 annually thereafter)
• $500/month ($6,000/year) bonus for employees who commit to working at least 3 days per week in our offices, plus generous commuter benefits ($315/month towards transit, rideshare, bike rental, or parking at our HQ office in San Francisco)
• Free Gympass subscription — an all-in-one corporate benefit that gives employees the largest selection of gyms, studios, classes, training and wellness apps
• Dog-friendly office
• And much more!

For California Residents: Philo’s CCPA Notice at Collection – Employees, Applicants, Owners, Directors, Officers and Contractors

Pursuant to the San Francisco Fair Chance Ordinance, we will consider for employment qualified applicants with arrest and conviction records.

About Acceleron Fusion:
Acceleron Fusion is developing muon‑catalyzed fusion—a path to clean, abundant energy. Building on research sponsored by the U.S. DOE, we have recently raised a $24M Series A venture capital round and have already logged 100+ hours of muon-catalyzed fusion in tests at the Paul Scherrer Institute. Our collaborators include PSI, Oak Ridge, Argonne, Fermilab, and several universities. Join a team where fundamental physics meets application-oriented engineering, and your designs could help move our technology from the laboratory to a commercial energy source.

About this role:
We’re looking for a high-voltage electrical systems engineer to design advanced beam-control hardware for our fusion experiments. You will develop high-voltage and RF solutions that enable precise manipulation of particle beams at energies from kilovolts to megavolts.  

What you’ll do:

• Analyze, model, and mitigate electrical-breakdown and insulation challenges in high-voltage structures and circuits.
• Design kilovolt-to-megavolt electrostatic systems—for example using Marx generators, Cockcroft‑Walton stacks, or Pelletrons —for particle beam acceleration and cooling.
• Architect RF power and energy recovery systems using Klystrons, Magnetrons, waveguides, and similar components.
• Build multiphysics models incorporating electromagnetics, heat transfer, fluid flow, and particle transport.
• Build prototypes and conduct lab tests.
• Generate clear design docs, test plans, and risk analyses that support rapid iteration and safe operations.
• Travel with the team (including international travel) to integrate your hardware at beamline facilities and carry out experiments.

What we’re looking for:

• B.S., M.S., or Ph.D. in Electrical Engineering, Physics, or a closely related field.
• Five years experience designing high voltage or pulsed power systems.
• Proficiency with COMSOL, ANSYS, or similar multiphysics simulation tools.
• Proficiency with circuit design tools (e.g. Altium).
• Hands‑on lab experience: high voltage safety standards and best practices; lab instrumentation; practical troubleshooting.
• Thoughtful collaboration skills, able to interact and work closely with people from other technical disciplines and backgrounds.
• Demonstrated time management and organizational skills.
• Excellent written and verbal communication abilities.

Preferred Qualifications (not required):

• Experience with particle accelerators, charged particle optics, or high vacuum systems.
• Proficiency with GEANT4, FLUKA, MCNP, or similar Monte Carlo simulation tools.

Details & Logistics:

• This is a full-time, onsite role working from our facility in Cambridge, MA.
• Travel (including international) for several weeks per year is required.
• Our benefits package includes health & dental insurance, retirement savings with company contribution, stock options, paid time off, and 11 company holidays.
• The salary range for this role is $110K to $150K. This range represents the minimum and maximum base compensation Acceleron Fusion reasonably expects to pay for this position. The specific salary offered will be determined based on relevant factors including skills, experience, qualifications, and location. This position may also be eligible for additional compensation such as bonuses, equity, or other benefits.
• Candidates who don’t meet all of our requirements are encouraged to apply.

#LI-Onsite

About PhaseV

PhaseV is a Boston-based technology company that redefines clinical development at scale with its enterprise-ready, multi-modal AI/ML platform — accelerating decisions, de-risking trials, and driving more efficient portfolio strategies. With over $65M raised from Accel, Insight, and others, we are poised to make a significant impact on how drugs are developed and brought to market.

Trusted by 45+ pharmaceutical sponsors and CROs, our causal AI technology identifies responder subgroups with greater precision, optimizes trial designs, life cycle management, site selection, and monitors trial performance in real-time to help bring treatments to patients faster. 

The Role

We're hiring our first dedicated marketer to lead our marketing strategy in support of our continued growth.  This is a rare opportunity to continue to architect our brand presence and dramatically expand PhaseV’s share of voice 

You will report to the Head of Strategy and Transformation, and work directly with the PhaseV leadership team to implement marketing strategies that build our sales pipeline, enable our sales team, and generate the target ROI. This includes refining the PhaseV story and pitch, and establishing PhaseV as the category leader in AI-powered clinical development. This role combines strategic thinking with hands-on execution—you'll set the vision and roll up your sleeves to make it happen in partnership with Business Development, Strategy, and Product.

What You'll Own

Pipeline & Lead Generation

• Own marketing’s contribution to pipeline generation in partnership with Business Development and Alliance Management
• Build and continuously improve PhaseV’s lead engine across channels (events, digital campaigns, outbound support, partnerships)
• Develop targeted marketing initiatives to support strategic opportunities
• Define, track, and report key funnel metrics (Marketing QL → Sales QL →Pipeline → Signed)
• Partner with BD to operationalize lead capture and follow-up workflows, ensuring conferences and campaigns convert into active opportunities
• Test and scale new growth experiments (paid LinkedIn, SEO, search/social, email, webinars, newsletter, blog, sponsored content, nurture sequences) to expand top-of-funnel awareness and engagement
• Own marketing attribution and performance analytics to ensure spend translates into measurable commercial outcomes
• Create and manage social media presence, particularly LinkedIn thought leadership

Brand & Narrative

• Develop and execute PhaseV's overall brand, marketing, and PR strategy across all channels
• Craft storytelling that cuts through the complexity of causal ML and clinical trials—moving audiences emotionally, intellectually, and commercially
• Manage external PR agency to secure coverage, speaker opportunities, and category-defining moments
• Own and refine PhaseV's visual brand and identity, managing external designers, as needed
• Ensure our website is built and optimized to serve as the central hub of our brand and engage our audience effectively

Events & Conferences

• Track, prioritize, and manage PhaseV's conference pipeline, standardize pre-/post-event workflows, clearly defined handoffs with conference attendees
• Lead our presence at major industry events from booth strategy to activations to follow-up campaigns
• Maximize commercial outcomes through pre-, during-, and post-event workflows
• Identify and execute ad-hoc opportunities for lead engagement (i.e. organizing sponsor dinners or other side-engagements) 

Cross-Functional Leadership

• Set marketing priorities and plan in partnership with Business Development, Alliance Management, Strategy, and Product teams to ensure message-market alignment
• Define KPI targets and report marketing performance to leadership team and drive marketing decisions
• Identify new business opportunities through market insights and customer feedback
• Define and manage marketing budget in collaboration with Finance

What You Bring

Required Experience

• 6+ years of modern marketing experience in brand, content, digital, or integrated marketing roles, including examples of driving marketing decisions
• 3+ years of exposure to pharmaceuticals, biotech, or healthcare
• Proven track record building brand identity and contributing to sales metrics, ideally at high-velocity startups
• Experience developing and measuring analytically rigorous full-funnel marketing campaigns
• Demonstrated ability to present to and influence executive teams
• Project management expertise in fast-moving, cross-functional environments
• Experience launching innovative products or establishing new market categories

Skills & Attributes

• Builder: Excited to own marketing from zero to one and thrive in a start-up environment
• Operator: You can run multiple workstreams at speed with precision and sound judgment
• Storyteller: You can make complex science and technology commercially compelling  
• Business Partner: Obsessed with pipeline impact and sales enablement
• High Taste Level: You prioritize clarity, design, tone, and quality
• Cross-Functional Leader: You build strong partnerships across BD, Product, Strategy, and leadership

Preferred

• Global marketing experience across varied business landscapes
• Experience with technical products involving complex scientific concepts
• Track record of successful product launches in competitive, technical markets
• Fluency with modern marketing tools and platforms

What we offer

• Join us on a mission to change the world for the better
• The opportunity to work with a mission-driven team pushing the frontier of data driven AI/ML powered clinical development
• A diverse and intellectually rigorous environment focused on solving some of the most complex challenges in clinical development
• A collaborative and dynamic startup environment
• Professional growth and development opportunities
• Competitive compensation and equity participation
• Comprehensive benefits, 401(k) match, and flexible hybrid culture

PhaseV is an equal opportunity employer. We celebrate diversity and are committed to creating an inclusive environment for all employees.