As a member of the pharmacology group, we seek a scientifically curious and motivated individual with an ability to work in a fast-paced environment. The potential Research Associate will develop and execute the ligand binding assay based bioanalytical method development to support pharmacokinetics (PK) sample analysis. In addition, the candidate will have opportunity to analyze high volume of data and to develop in vitro assays for compound characterization using ELISA, Octet, and cell-based assays. This position is hands-on and requires the effective experiment execution, communication, and documentation of results that enable the advancement of novel research molecules toward development candidates. Strong candidates will be hard working, efficient, collaborative, and passionate about drug discovery and development. Experience in ligand binding assay development and routine sample analysis is desired. This position will report directly to the Scientist of in vivo Pharmacology.
ESSENTIAL FUNCTIONS AND RESPONSIBILITIES
These may include, but are not limited to:
Identify, develop and execute ligand binding assays and other in vitro assays to support both in vivo and in vitro pharmacology studies.
Proven track record of ligand binding assay development and participation of routine preclinical and/or clinical sample analysis. Execute assays from assay development, qualification (if required), sample analysis, data analysis, and report by following the instruction or established procedure.
Analyze and present experimental data using Prism, Excel, MS Office or similar software.
Produce detailed documentation of experiments within a lab notebook and electronically.
Ability to schedule and prioritize workload effectively within a multi-task environment.
EDUCATION, EXPERIENCE, KNOWLEDGE, SKILLS AND ABILITIES
A bachelor’s degree with a minimum of 2 years of relevant experience or a master’s degree with a minimum of 1 year of relevant industry experience.
Experience in ligand binding assay development, qualification/validation and sample analysis.
Competence in data analysis tools (Excel, GraphPad). Candidates with experience in data management, coding and programming in Excel or other data management software would be a plus.
Hands-on expertise with ELISA and MSD is highly desirable.
Experience with cell-based assays is a plus.
Experience with immunogenicity/ADA sample analysis is a plus.
Ability to perform routine testing and to follow SOPs in a highly accurate and reproducible manner.
Strong analytical and critical thinking skills with the ability to work in a fast-paced and collaborative environment.
Excellent written and oral communication skills.
Job Type: Full-time
Benefits:
· Annual bonus program
· Incentive stock option plan
· 401k plan with flat non-elective employer contribution
· Comprehensive medical insurance with 90-100% employer-paid premiums
· Dental and vision insurance
· HSA, FSA, and supplemental insurance plans (life, disability, accident, critical illness, hospital indemnity)
· Unlimited PTO
· Generous holiday schedule; includes summer and winter company shutdown
· Relocation assistance
Schedule:
· Monday to Friday
Work authorization:
· United States (Required)
Additional Compensation:
· Annual targeted bonus %
Work Location:
· On site (San Diego, CA)
EQUAL OPPORTUNITY EMPLOYER:
Janux Therapeutics, Inc. is an equal opportunity employer that is committed to providing a work environment free of harassment and discrimination based upon a protected category, as well as an environment free from retaliation for protected activity.
Notice to Recruiters and Third-Party Agencies
The Talent Acquisition team manages the recruitment and employment process for Janux. To protect the interests of all parties involved, Janux will only accept resumes from a recruiter once a fully-executed search agreement is in place. Agencies are hereby specifically directed not to contact Janux employees directly in an attempt to present candidates. Janux will consider any candidate for whom an Agency and/or Recruiter has submitted an unsolicited resume to have been referred, free of any charges or fees.
