Lead Scientist, Purification Development 

As a Lead Scientist, you will be joining Purification Development team in Lonza Singapore. This group is responsible for the development and characterization of downstream manufacturing processes used to produce novel therapeutic recombinant proteins for Lonza’s global client base. The role provides scientific leadership for process development and characterization activities, serves as a downstream subject matter expert, and delivers technical support for manufacturing and regulatory submission activities.

What you’ll get  

• An agile career and dynamic working culture in a global life sciences leader.  

• An inclusive and ethical workplace that values diversity and integrity.  

• Competitive compensation programs that recognize high performance.  

• Professional growth opportunities through cross-functional projects and global exposure.  

• Comprehensive medical insurance, with the option to enroll family members at partially subsidized premiums.  

• Company transport provided from designated MRT locations to and from the Tuas site.  

• Access to Lonza’s full suite of employee benefits: www.lonza.com/careers/benefits  

What you’ll do: 

• Lead and oversee Process Development, Process Characterization, and/or Viral Clearance activities, including study planning, technical supervision, and interpretation of study outcomes.  

• Drive small-scale model studies such as risk assessments (FMEA), scale-down model qualification, Design of Experiments (DoE), resin reuse/lifetime studies, and activities supporting regulatory submissions.
• Lead and support purification activities, including chromatography (Affinity, Mixed-Mode, and Ion Exchange) using ÄKTA/UNICORN systems, ultrafiltration/diafiltration (UF/DF), and viral reduction studies. 
• Train and mentor junior scientists and new hires in the execution of laboratory activities, while providing training in purification technologies and laboratory techniques. 
• Prepare and review high-quality protocols, reports, SOPs and technical documentation. 
• Act as project representative for internal and external customer communication and coordinate multiple projects to ensure timely delivery. 
• Provide scientific and technical support for manufacturing operations, troubleshooting activities, and technology transfer initiatives. 
• Contribute to scientific excellence, operational improvements, safety and departmental training initiatives. 

What we’re looking for:  

• Degree/PhD in Life Sciences or a related field, with relevant industry experience. 

• 4–7 years’ experience in protein purification/process development; PhD candidates with 2–5 years’ experience may also be considered. 

• Strong expertise in protein purification, with experience in Process Characterization. Experience in , Process Validation and/or Viral Clearance studies is advantageous.. 

• Experience  with statistical software (e.g., JMP) for , DoE data analysis is highly advantageous. 

• Understanding of cGMP/BLA requirements is preferred. 

• Strong technical writing, communication, problem-solving and analytical skills. 

• Good team player with the ability to work collaboratively across projects. 

• Final role/level will be commensurate with experience. 

About Lonza  

At Lonza, our people are our greatest strength. With 30+ sites across five continents, our globally connected teams work together every day to manufacture the medicines of tomorrow. Our core values of Collaboration, Accountability, Excellence, Passion and Integrity reflect who we are and how we work together. Everyone’s ideas, big or small, have the potential to improve millions of lives, and that’s the kind of work we want you to be part of.  

Innovation thrives when people from all backgrounds bring their unique perspectives to the table. At Lonza, we value diversity and are committed to creating an inclusive environment for all employees. If you’re ready to help turn our customers’ breakthrough ideas into viable therapies, we look forward to welcoming you on board.  

Ready to shape the future of life sciences? Apply now