At Caris, we understand that cancer is an ugly word—a word no one wants to hear, but one that connects us all. That’s why we’re not just transforming cancer care—we’re changing lives.

We introduced precision medicine to the world and built an industry around the idea that every patient deserves answers as unique as their DNA. Backed by cutting-edge molecular science and AI, we ask ourselves every day: “What would I do if this patient were my mom?” That question drives everything we do.

But our mission doesn’t stop with cancer. We're pushing the frontiers of medicine and leading a revolution in healthcare—driven by innovation, compassion, and purpose.

Join us in our mission to improve the human condition across multiple diseases. If you're passionate about meaningful work and want to be part of something bigger than yourself, Caris is where your impact begins.

Position Summary
The Senior Payroll Accountant is responsible for supporting the accounting department and Company by ensuring the integrity of financial information and results through compliance with Company policies and procedures and Generally Accepted Accounting Principles (GAAP). Responsibilities include the ownership of domestic and international payroll and benefits, including expenses, accruals, and prepaid accounts and the production of financial and regulatory reports based on those records. Other responsibilities include performing accounting and financial analysis, preparing account reconciliations and assisting in the preparation of accounting statements and reports. This role will partner closely with Human Resources and other cross-functional teams to support month-end close and ongoing financial operations.

Job Responsibilities

• Complete month-end, quarter-end, and year-end close activities related to payroll and benefits expenses, accruals, and prepaid accounts

• Prepare journal entries, account reconciliations, and supporting schedules

• Perform domestic and international payroll accounting, including verification of expense classifications and accrual estimates

• Maintain bonus schedules, tax receivables and liabilities, and benefits liability balances

• Coordinate with business partners to ensure completeness and accuracy of accruals

• Analyze expense trends and variances and provide explanations to management

• Organize and evaluate prepaid expenses and balances, ensuring proper amortization and accurate period recognition, according to policy

• Collaborate cross-functionally to support business initiatives and financial transparency

• Identify opportunities to streamline processes, improve efficiency, and enhance controls

• Assist with system implementations or upgrades related to accounting processes

• Prepare and review financial reports for accuracy; complete any additional review or investigation required

• Research and respond to financial inquiries from management

• Participate in preparation of complex schedules and documentation for internal and external audits, both domestic and international

• Ensure timely and accurate financial reporting in accordance with U.S. GAAP

• Assist as needed to perform other related duties and special projects as requested

• Accept other duties as assigned

Required Qualifications

• Bachelor’s degree required

• 5+ years of experience working in accounting preferably in a Big 4 or large company, with 3+ years preferred specifically in payroll accounting

• Strong experience with month-end close

• Strong knowledge of Microsoft Office Suite, specifically Word, Excel, and Outlook

• Demonstrated ability to learn new accounting software

• Ability to work in a fast-paced deadline driven environment

Preferred Qualifications

• CPA preferred

• Drive for Results (Service, Quality, and Continuous Improvement): Ensure procedures and processes are in place that lead to delivery of quality results and continually reassess their effectiveness to achieve continuous improvement

• Communication: Proficient verbal and written communication skills; willingness to share and receive information and ideas from all levels of the organization to achieve the desired results

• Teamwork: Commitment to the successful achievement of team and organizational goals through a desire to participate with and help other members of the team

• Customer Service Focus: Demonstrate a focus on listening to and understanding client/customer needs and then delighting the client/customer by exceeding service and quality expectations

Physical Demands

• Must possess ability to sit and/or stand for long periods of time

• Must possess ability to perform repetitive motion

Training

• All job specific, safety, and compliance training are assigned based on the job functions associated with this employee

Conditions of Employment:  Individual must successfully complete pre-employment process, which includes criminal background check, drug screening, credit check ( applicable for certain positions) and reference verification.

This job description reflects management’s assignment of essential functions. Nothing in this job description restricts management’s right to assign or reassign duties and responsibilities to this job at any time.

Caris Life Sciences is an equal opportunity employer. All qualified applicants will receive consideration for employment without regard to race, religion, color, national origin, gender, gender identity, sexual orientation, age, status as a protected veteran, among other things, or status as a qualified individual with disability.