The Opportunity:

The Executive Director, Clinical Supply Chain provides strategic leadership and operational oversight for end-to-end clinical supply chain activities across the organization.

Strategic Leadership

• Define and execute the global clinical supply chain strategy aligned with the company’s clinical development pipeline and long-term business goals.

• Establishes strategies and processes to ensure uninterrupted supply for Revolution Medicines portfolio across all phases of development.

• Lead and serve as subject matter expert for clinical supply chain planning, risk management, and execution of clinical supply chain activities.

• Build scalable processes and infrastructure to support early- through late-phase clinical programs.

• Strategic Planning on comparator sourcing management to ensure timely, compliant and cost-effective product availability.

• Effective management of clinical studies executed in conjunction with collaboration partners.

• Identify and implement overall clinical supply chain best practices.

Clinical Supply Operations

• Oversee end-to-end clinical supply activities, including demand forecasting, protocol reviews, packaging, labeling, distribution, and returns.

• Ensure uninterrupted supply of investigational medicinal products (IMP), including RevMed and comparator products.

• Champions monthly Development Operations planning (DnOP) process in collaboration with PDM and Clinical Operation team members.

• Ensures efficient global clinical supply chain distribution networks are in place.

• Oversee comparator products demand and supply planning with expert level knowledge in comparator drugs and co-medications sourcing strategy

Cross-Functional Collaboration

• Partner with Clinical Operations and Clinical Study Execution Teams (CSET) in study planning and execution.

• Collaborate with PDM, Quality, and Regulatory to ensure compliant manufacturing, labeling, and distribution

• Work closely with Finance on budgeting, forecasting, and cost optimization.

• Work effectively with internal and external partners to develop sound strategies, identify and mitigate risks, and resolve issues as they arise.

Compliance & Quality

• Ensure all clinical supply activities comply with GxP, ICH, FDA, EMA, and global regulatory requirements.

• Expert knowledge of applicable GxP requirements and applicable regulatory guidances.

• Lead inspection readiness activities as required for global filings and maintain and inspection ready organization.

Team Leadership

• Build, lead, and mentor a high-performing clinical supply chain organization. Drives for excellence in execution of agreed upon strategies.

• Establish clear performance metrics, development plans, and succession planning.

• Foster a culture of accountability, continuous improvement, and collaboration.

• Drives excellence in setting clear and actionable team goals.

Required Skills, Experience and Education:

• Bachelor’s degree in Supply Chain, Business, Engineering or Life Sciences with 20+ years of experience in pharmaceutical supply chain. Master’s degree (MS, MBA) with at least 18 years of experience in pharmaceutical/biotech supply chain.

• CPIM/CSCP certifications a plus.

• At least 5 years of experience in a leadership/supervisory role.

• Strong knowledge and experience with cGMP operations for small molecules, end- to end supply chain and demand/supply planning.

• Effective vendor management and oversight skills

• Excellent cross-functional leadership skills with effective communication skills.

Preferred Skills:

• Proven leadership experience hiring, managing and developing teams.

• Knowledge and experience with outsourced manufacturing operations. (CMO’s)

• Effective, open and transparent communication skills (verbal and written). Strong analytical, communication and executive level reporting skills.

• Capable of working on multiple projects/tasks and able to meet timelines.

• Self-starter with a high-level of comfort with ambiguity and complexity and the ability to multi-task while consistently delivering quality results.

• Team-oriented, progressive thinker who enjoys participating in an innovative and creative work environment. 

  #LI-Hybrid  #LI-GL1