We are Pierre Fabre Laboratories, a global leader combining pharmaceutical expertise with dermo-cosmetics to support consumers and patients at every stage of their care journey.
Our portfolio includes several medical franchises and international brands such as Eau Thermale Avène, Ducray, A-Derma, Klorane, René Furterer, and Pierre Fabre Oral Care.
By joining us, you become part of a meaningful company where the human dimension is essential. You become a participant in the "We Care Movement," a movement that values excellence and innovation within passionate teams. Together, we push the boundaries of science to unite health and beauty for the benefit of all, because Every time we care for a single person, we make the whole world better.

Present in 120 countries with a team of over 10,000 employees, we are proud to create a scientific and human impact, today and tomorrow! If caring is at the heart of your values, join Pierre Fabre Laboratories and become a key player in the “We Care Movement".

Your mission

Votre rôle au sein d’une entreprise pionnière en pleine expansion.

Dans le cadre de nos activités de recherche en oncologie, nous souhaitons développer une méthode de prédiction des mutations de résistance aux traitements anticancéreux. L'objectif du stage est de tester la robustesse et la pertinence d’outils existants et de developer une pipeline de prédiction de résistance applicable à différentes cibles thérapeutiques.

Dans le cadre de votre stage, vos missions principales seront :

• Création d’un jeu de données publiques et internes pour la validation d’outils.
• Exécuter les outils de prédiction et évaluer leurs performances (sensibilité, spécificité, faux positifs/négatifs)
• Identifier les limites et développer une méthode applicable à différentes cibles thérapeutiques
• Documenter le protocole et les résultats, et formuler des recommandations sur l'usage des outils (cas d'application, limites)
• Présenter l'avancement et les conclusions à l'équipe tout au long du stage

Les plus du stage :

• Missions diversifiées 
• Gratification attractive
• Possibilité de réaliser un jour de télétravail par semaine après un mois d'intégration
• Dotations produits 
• Restaurant d'Entreprise ou Titres Restaurants

Le stage se déroulera sur notre site Langlade, à Toulouse (31) et débutera à partir de janvier 2027.

Merci d’indiquer vos dates de disponibilités dans votre CV.

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Your role within a pioneering, rapidly expanding company.

As part of our oncology research activities, we aim to develop a method for predicting resistance mutations to anticancer treatments. The goal of the internship is to test the robustness and relevance of existing tools and to develop a resistance-prediction pipeline applicable to different therapeutic targets.

Main Tasks

• Building a public and internal dataset for tool validation.
• Running prediction tools and evaluating their performance (sensitivity, specificity, false positives/negatives)
• Identifying limitations and developing a method applicable to different therapeutic targets
• Documenting the protocol and results, and making recommendations on tool usage (use cases, limitations)
• Presenting progress and conclusions to the team throughout the internship

Internship Benefits:

• Diverses missions
• Attractive compensation
• Possibility to work one day remotely per week after one month of integration
• Product allowances
• Company Restaurant or Meal Vouchers

The internship will take place on our site Langlade, Toulouse (31) and start january 2027.

Please indicate your availability dates in your CV.

# Young People

Vos compétences au service de projets novateurs.

Nous recherchons un étudiant(e) en Master 2 (chimie informatique, chimie computationnelle, biologie structurale, biologie computationnelle, bio-informatique, ou équivalent).

• Une bonne compréhension des interactions protéine-ligand est nécessaire
• Savoir exploiter les bases de données publiques COSMIC, cBioPortal, TCGA, …
• La connaissance de la base de données MdrDB est un plus.
• Bonnes connaissances en biologie structurale et en modélisation de protéines
• Bases en génomique du cancer et en biologie moléculaire (mutations somatiques, mécanismes de résistance aux traitements)
• Notions de base en manipulation de fichiers de séquences/structures (FASTA, PDB)
• Savoir travailler avec les lignes de commandes Linux et coder en Python
• Rigueur, autonomie et esprit critique, notamment pour la validation méthodologique
• Bon niveau de rédaction scientifique (français et/ou anglais)

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Put your skills to work on innovative projects

Candidate Profile : Master’s student (2nd year) in cheminformatics, computational chemistry, structural biology, computational biology, bioinformatics, or a related field

• A good understanding of protein–ligand interactions is required
• Ability to work with public databases such as COSMIC, cBioPortal, TCGA, …
• Familiarity with the MdrDB database is a plus.
• Good knowledge of structural biology and protein modeling
• Basic knowledge of cancer genomics and molecular biology (somatic mutations, treatment-resistance mechanisms)
• Basic skills in handling sequence/structure files (FASTA, PDB)
• Comfortable working with the Linux command line and coding in Python
• Rigor, autonomy, and critical thinking, particularly for methodological validation
• Good scientific writing skills (French and/or English)

At Pierre Fabre Laboratories, we believe that our greatest asset is our people.

We are committed to a policy of Equal Employment Opportunity and will not discriminate against an applicant or employee based on race, color, religion, creed, national origin or ancestry, sex, sexual orientation, gender identity or expression, age, physical or mental disability, veteran or military status, genetic information, or any other legally recognized protected basis under federal, state, or local law. The information collected by this application is solely to determine suitability for employment, verify identify, and maintain employment statistics on applicants. Applicants with disabilities may be entitled to reasonable accommodation under the Americans with Disabilities Act and certain state or local laws. Please inform the company’s personnel representative if you need assistance completing this application or to otherwise participate in the application process. Thus, we commit to considering all applications equally, without fail.