Location: Onsite – Boston (Seaport), MA – Remote work is not offered with this role.

Rare disease biopharma at Alexion, a division of AstraZeneca, is at the forefront of biomedical science. Remaining transparent, objective and ethical, we push the boundaries of science, translating complex biology into transformative medicines. Uniquely positioned – with resources and global reach – we also have potent capabilities that are shaping the future of Rare disease into new areas of great unmet need to help people fully live their best lives.

This is what you will do:

The Director, Strategic Pricing Management will shape US pricing strategies for pipeline and in-line products across Alexion’s rare disease portfolio. Based in Boston Seaport, you will report to the Executive Director, US Strategic Contracting & Pricing and serve as a senior advisor on pricing decisions that balance patient access, payer value, sustainable revenue, and long-term business performance.

In this role, you will partner with global and US teams to support new launches, address complex pricing challenges, and bring clear, evidence-based recommendations to senior leaders.

Why this role matters:

Alexion’s robust rare disease pipeline, global reach, and evolving launch priorities create a meaningful opportunity to shape pricing strategy at a critical time. The US pricing environment is also changing quickly, with Most-Favored-Nation policy activity and broader pricing reforms increasing pressure on launch assumptions, payer value, access strategy, and long-term revenue planning. This leader will help translate that external complexity into practical, evidence-based pricing recommendations for the future.

You will be responsible for:

• Developing US list pricing strategies for pipeline assets and price evolution strategies for in-line products.
• Assessing pricing impacts on patient access, gross-to-net, ASP, government pricing, and net revenue.
• Partnering with Global Market Access, HEOR, Contracting, Finance, Commercial, and Marketing teams to support launch and in-line pricing decisions.
• Evaluating value-based agreement opportunities and other innovative pricing approaches.
• Creating clear recommendations for senior leaders and influencing decisions across cross-functional and global forums.

You will need to have at minimum:

• Bachelor’s degree or equivalent experience in life sciences, business, finance, economics, or a related field.
• At least 7 years of relevant experience in biopharma pricing, market access, strategic contracting, commercial strategy, HEOR, consulting, or a related area.
• US pricing strategy experience, including launch, indication expansion, portfolio, or in-line pricing work.
• Strong understanding of the US payer, provider, reimbursement, and drug pricing landscape.
• Experience communicating complex analysis and recommendations to senior leaders.
• Strong analytical, strategic thinking, influencing, project management, and problem-solving skills.
• Advanced Microsoft Excel skills, including PivotTables, scenario analysis, and financial modeling.
• Ability to travel up to 10% overnight.

We would prefer you to have:

• Advanced degree, such as a master’s, MBA, PhD, JD, or PharmD.
• 10+ years of relevant biopharma experience, including product launch experience.
• Experience pricing rare disease or specialty therapies with complex reimbursement dynamics.
• Advanced pricing or revenue analytics experience, including GTN forecasting, price-volume analysis, government pricing assessments, or value-based agreement modeling.
• Practical experience using AI-enabled tools to improve pricing research, scenario planning, workflow efficiency, insight generation, or decision support.
• Executive presence and the ability to build alignment, challenge assumptions constructively, and influence senior and global stakeholders.

Pay Transparency/ On-Site Office policy

The annual base pay for this position ranges from $215,000 - $250,678 USD Annual. Hourly and salaried non-exempt employees will also be paid overtime pay when working qualifying overtime hours. Base pay offered may vary depending on multiple individualized factors, including market location, job-related knowledge, skills, and experience. In addition, our positions offer a short-term incentive bonus opportunity; eligibility to participate in our equity-based long-term incentive program (salaried roles), to receive a retirement contribution (hourly roles), and commission payment eligibility (sales roles). Benefits offered included a qualified retirement program [401(k) plan]; paid vacation and holidays; paid leaves; and, health benefits including medical, prescription drug, dental, and vision coverage in accordance with the terms and conditions of the applicable plans. Additional details of participation in these benefit plans will be provided if an employee receives an offer of employment. If hired, employee will be in an “at-will position” and the Company reserves the right to modify base pay (as well as any other discretionary payment or compensation program) at any time, including for reasons related to individual performance, Company or individual department/team performance, and market factors.

When we put unexpected teams in the same room, we unleash bold thinking with the power to inspire life-changing medicines. In-person working gives us the platform we need to connect, work at pace, and challenge perceptions. That's why we work, on average, a minimum of three days per week from the office. But that doesn't mean we're not flexible. We balance the expectation of being in the office while respecting individual flexibility. Join us in our unique and ambitious world.

At AstraZeneca's Alexion division, you'll find a unique opportunity where work transcends ordinary boundaries. Our commitment to patients drives everything we do; it's about knowing them by name and understanding their journeys. With a rapidly expanding portfolio in rare diseases, you'll thrive in an entrepreneurial environment that encourages innovation. Here, you'll be part of a team that values diversity and inclusiveness while making a tangible impact on patients' lives. Your career path will be supported by tailored development programs that align your growth with our mission.

Date Posted

Closing Date

Our mission is to build an inclusive environment where equal employment opportunities are available to all applicants and employees. In furtherance of that mission, we welcome and consider applications from all qualified candidates, regardless of their protected characteristics. If you have a disability or special need that requires accommodation, please complete the corresponding section in the application form.