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Alumis Inc. is a precision medicines company with the mission to transform the lives of patients with autoimmune diseases. Even with treatment innovations of the last two decades, many patients with immunologic conditions continue to suffer - our goal is to fundamentally change the outcomes for these patients.
Alumis Inc is a precision medicines company with the mission to transform the lives of patients with autoimmune diseases. Even with treatment innovations of the last two decades, many patients with immunologic conditions continue to suffer – our goal is to fundamentally change the outcomes for these patients.
We are seeking a Data Science leader within Statistical Programming to advance analytical insights across clinical development while supporting high-quality, submission-ready deliverables. You will employ modern data science methods and tools such as machine learning, generative AI, and agentic AI to strengthen statistical programming and elevate analytical insight generation. You will contribute to both clinical data science (enhancing analyses, insights, and submissions) and operational/enterprise analytics (improving efficiency, scalability, and decision-making across Biometrics).
Depending on level, this individual will operate as a hands-on study/program contributor (Senior Manager) or a program-level leader influencing strategy and cross-functional execution (Associate Director).
This role is located in South San Francisco, CA, with an on-site presence expected Tuesday through Thursday. Remote candidates may remain off-site but should be willing to travel regularly for team collaboration.
Alumis Inc. is an equal opportunity employer.
The salary range for this position is Senior Manager: $180,000 - $200,000 annually and Associate Director: $200,000 - $220,000 annually. This salary range is an estimate, and the actual salary may vary based on the Company’s compensation practices.
Alumis compensation packages include generous stock option grants for all employees as well as an annual bonus program.
Other benefits include:
We are a hard-working, collaborative team on a mission to transform patient’s lives-- and we aspire to elevate, challenge and nurture one another along the way.
Ready to apply?
Apply to AlumisAlumis Inc. is a precision medicines company with the mission to transform the lives of patients with autoimmune diseases. Even with treatment innovations of the last two decades, many patients with immunologic conditions continue to suffer - our goal is to fundamentally change the outcomes for these patients.
This role will serve as a strategic and operational partner to the Vice President of Medical Affairs and Medical leadership team, and is responsible for ensuring that medical capabilities, processes, systems, and execution models are efficient, compliant, scalable, and aligned with Alumis’ growth strategy. The Senior Director, Medical Strategy and Operations, will be responsible for advancing key initiatives aimed at optimizing and showcasing the impact of the Medical Affairs team. This is a hands-on position that includes driving medical strategic initiatives, enhancing the Medical Affairs systems, supporting critical medical insights processes, and developing innovative solutions to measure and report on medical affairs performance and impact. The role demands an individual who combines scientific knowledge with strong operational leadership to thrive in a fast-paced, agile environment to elevate our medical affairs capabilities.
Key Responsibilities:
· Strategic Leadership: Lead and drive the development and execution of initiatives that elevate the strategic and operational effectiveness of the Medical Affairs team in a consistent and scalable manner.
· Medical Affairs Systems Optimization:
o Oversee the design, implementation, and optimization of our Medical Affairs systems to improve internal efficiencies, engagement and communications with key opinion leaders (KOLs), healthcare providers, and other relevant stakeholders.
o Lead continuous improvement initiatives to enhance efficiency, quality, and compliance across the Medical function.
o Implement best practices for operational metrics, KPIs, dashboards, and reporting to support data-driven decision-making.
· Medical Insights: Collaborate with Medical Affairs Leadership to collect, analyze, and integrate valuable medical insights that inform strategic decisions and optimize the impact of our medical programs.
· Content Management: Serve as Medical Affairs content owner through review and approval process for external-facing materials.
· Cross-functional Collaboration: Collaborate with other functional areas such as Clinical Development, Marketing, Market Access, Commercial, Analytics, Compliance, and Regulatory to ensure alignment and integration of medical excellence within the broader organizational strategy.
· Guidance and SOP Development: Leverage expertise to develop guidance documents and SOPs to foster consistency, clarity, and accountability across Medical Affairs.
· Planning, Budgeting & Resource Management
o Lead medical annual planning, forecasting, and budget management.
o Optimize headcount planning, vendor strategy, and external spend to maximize impact and efficiency.
o Provide transparency and insights into medical investments and their impact.
Qualifications:
· Experience: Minimum of 10 years in Medical Affairs leadership. Proven experience in managing and optimizing medical operations, systems, content, and medical insights. Experience in a fast-paced, small biotech environment a plus
Education: Advanced degree (PhD, MD, MBA, PharmD or similar)
· Leadership Skills: Exceptional leadership abilities with a demonstrated ability to manage cross-functional teams and drive change across complex medical operations. Must have track record of effectively leading without authority
· Operational Expertise: Strong experience in developing and managing Medical Affairs dashboards and other qualitative outcomes to measure impact and performance.
· Strategic Thinking: Ability to develop and implement strategic initiatives aligned cross-functionally that drive organizational goals and enhance the impact of Medical Affairs functions.
· Strong Communication: Excellent communication and interpersonal skills, with the ability to engage and influence stakeholders at all levels, both internally and externally.
The salary range for this position is $265,00 to 310,000 USD annually. This salary range is an estimate, and the actual salary may vary based on the Company’s compensation practices degree and background.
Alumis Inc. is an equal opportunity employer.
Alumis compensation packages include generous stock option grants for all employees as well as an annual bonus program.
Other benefits include:
We are a hard-working, collaborative team on a mission to transform patient’s lives-- and we aspire to elevate, challenge and nurture one another along the way.
Ready to apply?
Apply to AlumisAlumis Inc. is a precision medicines company with the mission to transform the lives of patients with autoimmune diseases. Even with treatment innovations of the last two decades, many patients with immunologic conditions continue to suffer - our goal is to fundamentally change the outcomes for these patients.
The small molecule CMC team is seeking highly motivated Sr. Scientist I of Analytical Development to help build our dynamic small molecule CMC group at Alumis. The successful candidate will help to support the analytical development and quality control activities from the preclinical phase through late-stage clinical development. Having analytical development expertise and experience in working with CMOs/CTLs, coupled with thorough understanding of the associated quality and regulatory awareness are key assets.
RESPONSIBILITIES
THE IDEAL CANDIDATE
This position is located in South San Francisco, CA. At this time, we are not considering fully remote applicants.
The salary range for this position is $112,000 USD to $135,000 USD annually. This salary range is an estimate, and the actual salary may vary based on the Company’s compensation practices.
Alumis Inc. is an equal opportunity employer.
Alumis compensation packages include generous stock option grants for all employees as well as an annual bonus program.
Other benefits include:
We are a hard-working, collaborative team on a mission to transform patient’s lives-- and we aspire to elevate, challenge and nurture one another along the way.
Ready to apply?
Apply to AlumisAlumis Inc. is a precision medicines company with the mission to transform the lives of patients with autoimmune diseases. Even with treatment innovations of the last two decades, many patients with immunologic conditions continue to suffer - our goal is to fundamentally change the outcomes for these patients.
Alumis Inc. is a precision medicines company with the mission to transform the lives of patients with autoimmune diseases. Even with treatment innovations of the last two decades, many patients with immunologic conditions continue to suffer - our goal is to fundamentally change the outcomes for these patients.
Alumis is seeking an experienced Director of Thought Leader Liaison (TLL) with deep expertise in Dermatology. This role is a field-based commercial leadership role responsible for leading a team of field based TLLs, to develop and execute Key Opinion Leader (KOL) engagement strategies for the US launch of envudeucitinib for Psoriasis.
The successful candidate will be a key member of the brand marketing team, working across multiple stakeholders at the intersection of marketing, medical, and field execution, with accountability for team leadership, KOL strategy and execution, and strategic insight generation to shape brand strategy. This role will require a deep understanding of medical science, excellent leadership capabilities, and a strong ability to drive the success of cross-functional teams.
Alumis Inc. is an equal opportunity employer.
Alumis compensation packages include generous stock option grants for all employees as well as an annual bonus program. The salary range for this position is $215,000-$260,000 USD annually. This salary range is an estimate, and the actual salary may very based on the Company’s compensation practices degree and background.
Alumis compensation packages include generous stock option grants for all employees as well as an annual bonus program.
Other benefits include:
We are a hard-working, collaborative team on a mission to transform patient’s lives-- and we aspire to elevate, challenge and nurture one another along the way.
Ready to apply?
Apply to AlumisAlumis Inc. is a precision medicines company with the mission to transform the lives of patients with autoimmune diseases. Even with treatment innovations of the last two decades, many patients with immunologic conditions continue to suffer - our goal is to fundamentally change the outcomes for these patients.
We are seeking an experienced and highly motivated Senior Scientist for the Drug Product Development group who can work in a collaborative and dynamic environment. The scientist in this role is responsible for activities critical to the development of Alumis’ molecules including generation of pre-formulation packages, formulation selection, and manufacturing process development. This primary focus of this role will currently be on solid oral dosage form development but may involve the development of other dosage forms in the future.
Responsibilities
Education
Ph.D. degree in Pharmaceutical Sciences, Chemistry, Engineering or related field with a minimum of 8 years or B.S. or M.S. with a minimum of 10+ years related industrial experience.
Alumis Values
This position is located in South San Francisco, CA with three (3) to five (5) days a week in lab. We are not considering remote applicants.
The salary range for this position is $139,000 USD to $169,000 US annually. This salary range is an estimate, and the actual salary may vary based on the Company’s compensation practices.
Alumis Inc. is an equal opportunity employer.
Ready to apply?
Apply to AlumisAlumis Inc. is a precision medicines company with the mission to transform the lives of patients with autoimmune diseases. Even with treatment innovations of the last two decades, many patients with immunologic conditions continue to suffer - our goal is to fundamentally change the outcomes for these patients.
We are seeking an exceptionally motivated individual to provide leadership and support to global regulatory activities to achieve Alumis’ strategic vision in obtaining worldwide approvals to market our products. The individual will represent Regulatory Affairs and work closely with cross-functional study teams and technical regulatory service providers in accordance with health authority and ICH requirements. In addition to being a key member of our project teams, she/he will provide organizational support as the company and its product development pipeline grow. This role will be reporting to the Director of Regulatory Strategy.
ESSENTIAL DUTIES & RESPONSIBILITIES
· Serve as the Regulatory Affairs representative for Phase 1 to Phase3 trials, ensuring regulatory activities are evaluated, prioritized and executed to meet global regulatory requirements.
· Serve as the Regulatory Affairs representative on assigned study teams and assure the progress of studies by addressing regulatory related queries in support of regulatory approvals.
· Lead preparation, review and submission of INDs/CTAs, amendments, review and approval of investigator document packages and manage other regulatory activities of the assigned studies as needed.
· Establish and meet timelines for regulatory submissions related to INDs/CTAs, including nonclinical, clinical, and CMC activities, while planning for Phase 1 to 3 trials.
· Interact with Contract Research Organization (CRO) Regulatory Affairs counterpart.
· Maintain awareness of current regulatory requirements and communicate requirements in support of regulatory approvals.
EDUCATION/EXPERIENCE/SKILLS:
· Bachelor’s or advanced degree in scientific discipline, with a minimum of 5 years of experience working in drug development in the biopharmaceutical industry and at least 3 years of experience in Regulatory Affairs; immunology or rare disease/ orphan drug development experience desirable.
Knowledge/Skills/Abilities:
· Direct experience with pharmaceutical global regulatory submissions and contributing to major regulatory filing(s) such as IND/CTA.
· Working knowledge of FDA regulations and practices and ICH guidance as well as strong knowledge of global health authority regulations and practices.
· Demonstrated experience in successfully leading assigned activities within cross-functional teams.
· Excellent verbal and written communication skills.
· Collaborative, analytical and interpretative skills that enable review and compilation of reports and other documents used in regulatory planning and submissions.
· Ability to work with minimal supervision, to set priorities to meet timelines, to motivate and influence others, prior management experience a plus.
· Responsibilities may require a work schedule that may include working outside of “normal” work hours, to meet business demands.
The salary range for this position is $165,000 USD to $195,000 USD annually paid hourly per contract. This salary range is an estimate, and the actual salary may vary based on the Company’s compensation practices.
Ready to apply?
Apply to AlumisAlumis Inc. is a precision medicines company with the mission to transform the lives of patients with autoimmune diseases. Even with treatment innovations of the last two decades, many patients with immunologic conditions continue to suffer - our goal is to fundamentally change the outcomes for these patients.
Alumis Inc. is a precision medicines company with the mission to transform the lives of patients with autoimmune diseases. Even with treatment innovations of the last two decades, many patients with immunologic conditions continue to suffer - our goal is to fundamentally change the outcomes for these patients.
The Director, Field Medical Excellence and Training will be responsible for overseeing and advancing key field-based initiatives that inform or support Medical Affairs strategies, and developing and executing a comprehensive medical training programs across therapeutic areas. The role demands an individual who combines experience in a fast-paced environment with scientific knowledge, excellence in field medical execution, and strong educational and operational leadership.
Key Responsibilities:
· Strategic Leadership:
· Lead and drive the development, implementation, and measurement of the effectiveness of field-based initiatives to inform or support launch and new product strategies.
· Assist with development and implement frameworks for field effectiveness, including KPIs, activity metrics, and qualitative impact measures.
· Support field medical launch readiness (territory design, targeting, resource planning)
· Training & Capabilities:
· Partner with Medical Training to identify capability gaps and support ongoing development of the field medical team
· Create tools and resources to improve field execution (e.g., engagement guides, scientific narratives)
· Fostering a team culture of accountability and develop a proactive approach to growing skillsets
· Medical Insights: Collaborate with Medical Affairs Leadership to develop and drive strategies to collect, analyze, and integrate valuable medical insights that inform strategic decisions.
· Field Resources: Assess field resources to ensure a high standard of tactical execution aligned with Medical Strategy.
· Cross-functional Collaboration: Collaborate with other functional areas such as Clinical Development, Commercial, Compliance and Regulatory to ensure alignment and integration of medical excellence within the broader organizational strategy.
Qualifications:
· Education: Advanced degree in life sciences (PhD, PharmD, masters or equivalent); degree or certificate in training or education a plus
· Experience: Minimum of 7+ years of Medical Affairs expereince, including 5 yrs in Field Medical. Proven experience in training Field Medical personnel and managing field-based initiatives.
· Leadership Skills: Must have track record of effectively leading without authority, a strong commitment to teamwork, coaching or mentoring, and emotional intelligence.
· Operational Expertise: Strong experience in utilizing systems to educate and manage field-based initiatives.
· Strategic Thinking: Ability to develop and implement strategic initiatives that drive organizational goals and enhance the impact of Medical Affairs functions.
· Strong Communication: Excellent communication and interpersonal skills, with the ability to engage and influence internal stakeholders at all levels.
Primarily US remote field-based with travel.
~25% travel required to professional conferences, internal meetings, and field co-rides, including some weekends
The salary range for this position is $220,00 to 265,000 USD annually. This salary range is an estimate, and the actual salary may vary based on the Company’s compensation practices degree and background.
Alumis Inc. is an equal opportunity employer.
Alumis compensation packages include generous stock option grants for all employees as well as an annual bonus program.
Other benefits include:
We are a hard-working, collaborative team on a mission to transform patient’s lives-- and we aspire to elevate, challenge and nurture one another along the way.
Ready to apply?
Apply to AlumisAlumis Inc. is a precision medicines company with the mission to transform the lives of patients with autoimmune diseases. Even with treatment innovations of the last two decades, many patients with immunologic conditions continue to suffer - our goal is to fundamentally change the outcomes for these patients.
Alumis is seeking a highly strategic and execution-oriented Senior Director, Trade Operations to lead the vision, design, and implementation of U.S. trade and distribution models across its dermatology and immunology portfolio. This individual will play a critical leadership role in shaping how products reach patients and providers through agile, efficient, and scalable access pathways.
Reporting to the SVP, Market Access, this role will operate as a core member of a lean, high-impact commercialization team. The ideal candidate thrives in a nimble environment, brings a pragmatic and innovative mindset, and is comfortable building strategy from the ground up while remaining deeply involved in execution.
The salary range for this position is $270,000 USD to $320,000 USD annually. This salary range is an estimate, and the actual salary may vary based on the Company’s compensation practices.
This position is based in South San Francisco. Local candidates (onsite Tues-Thurs) are preferred. Will consider excellent candidates nation-wide if they are willing to travel regularly to South San Francisco.
Alumis Inc. is an equal opportunity employer.
Alumis compensation packages include generous stock option grants for all employees as well as an annual bonus program.
Other benefits include:
We are a hard-working, collaborative team on a mission to transform patient’s lives-- and we aspire to elevate, challenge and nurture one another along the way.
Ready to apply?
Apply to AlumisAlumis Inc. is a precision medicines company with the mission to transform the lives of patients with autoimmune diseases. Even with treatment innovations of the last two decades, many patients with immunologic conditions continue to suffer - our goal is to fundamentally change the outcomes for these patients.
Alumis is seeking a high-impact Senior Director to help shape and deliver U.S. market access strategy for a late-stage immunology asset in dermatology. Reporting to the SVP of Market Access, this role is designed for someone who thrives in a lean environment, takes ownership beyond their title, and drives strategy through execution.
You will operate as a critical member of a small, senior team, expected to deliver outsized impact without the infrastructure of a large organization. This role is best suited for individuals who have succeeded in complex dermatology markets and are motivated to assess issues, identify feasible solutions, make decisions, and operate with efficiency.
The salary range for this position is $270,000 USD to $320,000 USD annually. This salary range is an estimate, and the actual salary may vary based on the Company’s compensation practices.
This position is based in South San Francisco. Local candidates (onsite Tues-Thurs) are preferred. Will consider excellent candidates nation-wide if they are willing to travel regularly to South San Francisco.
Alumis Inc. is an equal opportunity employer.
Alumis compensation packages include generous stock option grants for all employees as well as an annual bonus program.
Other benefits include:
We are a hard-working, collaborative team on a mission to transform patient’s lives-- and we aspire to elevate, challenge and nurture one another along the way.
Ready to apply?
Apply to AlumisAlumis Inc. is a precision medicines company with the mission to transform the lives of patients with autoimmune diseases. Even with treatment innovations of the last two decades, many patients with immunologic conditions continue to suffer - our goal is to fundamentally change the outcomes for these patients.
Alumis is hiring a Clinical Quality Assurance Director, (CONTRACTOR) reporting to the Executive Director, GCPQA. The role works closely with the Quality leadership and Study Execution Team members to provide ICH-GCP/GVP support for all ongoing clinical studies. This involves working closely with Clinical Operations, Clinical Development, Clinical Supply Chain, Data Management, Pharmacovigilance, Medical Affairs, Regulatory, Legal, and other teams across Alumis.
The Clinical QA Director is responsible to ensure quality is embedded throughout the lifecycle of all the ongoing clinical programs through oversight, assessment and monitoring, risk assessment tools, auditing and risk mitigations. The Director will assist with establishing Key Performance Indicators and Metrics to trend and track on the health of the clinical trials.
The role is responsible for providing the operational quality guidance for the development teams and supporting the Executive Director of GCP Quality in building the Alumis Quality organization strategy and vision.
This position requires expertise in Good Clinical and Pharmacovigilance Practices (ICH-GCP & GVP) and relevant US and EU regulations. The successful candidate will drive, promote, and embed a culture of ethics, integrity, and proactive quality management. The candidate will provide guidance and leadership to ensure that the quality function maintains the standards expected by global regulatory authorities.
ESSENTIAL DUTIES & RESPONSIBILITIES
EDUCATION & EXPERIENCE
KNOWLEDGE/ SKILLS/ ABILITIES
The salary range for this position is $193,000 USD to $242,000 USD annually. This salary range is an estimate, and the actual salary may vary based on the Company’s compensation practices.
This position is located in South San Francisco, CA and employees are expected to be onsite Tuesday-Thursday.
Alumis Inc. is an equal opportunity employer.
Ready to apply?
Apply to AlumisAlumis Inc. is a precision medicines company with the mission to transform the lives of patients with autoimmune diseases. Even with treatment innovations of the last two decades, many patients with immunologic conditions continue to suffer - our goal is to fundamentally change the outcomes for these patients.
The Director, Data Systems (DS) and Clinical Programming (CP) will be responsible for leading and managing the Clinical Programming function within Data Management (DM). This position will report to the VP, Data Management and Clinical Programming.
Alumis Values
• We Elevate
• We Challenge
• We Nurture
This position is located in South San Francisco, CA and employees are expected to be onsite Tuesday-Thursday. Open to remote applicants with requirement to be onsite 1-2x a quarter.
The salary range for this position is $200,000 USD to $225,000 USD annually. This salary range is an estimate, and the actual salary may vary based on the Company’s compensation practices.
Alumis Inc. is an equal opportunity employer.
Ready to apply?
Apply to AlumisAlumis Inc. is a precision medicines company with the mission to transform the lives of patients with autoimmune diseases. Even with treatment innovations of the last two decades, many patients with immunologic conditions continue to suffer - our goal is to fundamentally change the outcomes for these patients.
Alumis is seeking a Director of Clinical Pharmacology & DMPK to drive clinical pharmacology strategy and PK/PD modeling for our small-molecule programs in immune-mediated diseases. This role partners closely with cross-functional teams and reports to the Head of Clinical Pharmacology & DMPK.
Specific responsibilities include but are not limited to:
Key Requirements and Qualifications
Alumis Inc. is an equal opportunity employer.
The salary range for this position is $200,000 USD to $240,000 USD annually. This salary range is an estimate, and the actual salary may vary based on the Company’s compensation practices.
This position is located in South San Francisco, CA and employees are expected to be onsite Tuesday-Thursday.
Alumis compensation packages include generous stock option grants for all employees as well as an annual bonus program.
Other benefits include:
We are a hard-working, collaborative team on a mission to transform patient’s lives-- and we aspire to elevate, challenge and nurture one another along the way.
Ready to apply?
Apply to AlumisAlumis Inc. is a precision medicines company with the mission to transform the lives of patients with autoimmune diseases. Even with treatment innovations of the last two decades, many patients with immunologic conditions continue to suffer - our goal is to fundamentally change the outcomes for these patients.
Alumis Inc. is a precision medicines company with the mission to transform the lives of patients with autoimmune diseases. Even with treatment innovations of the last two decades, many patients with immunologic conditions continue to suffer - our goal is to fundamentally change the outcomes for these patients.
We are seeking an experienced Regional Director of Medical Science Liaisons (MSLs) with expertise in medical dermatology. The successful candidate will be responsible for leading and overseeing MSLs, ensuring the effective dissemination of scientific and clinical information, building relationships with key opinion leaders (KOLs), and supporting the strategic goals of the Medical Affairs organization. This role will require a deep understanding of medical science, excellent leadership capabilities, and a strong ability to drive the success of cross-functional teams. We will be seeking one individual for the Western US and one for the Eastern US.
Responsibilities:
Field-based Leadership of Regional DPEGs and IDNs
Serve as primary point of contact with the clinical leaders, educational leaders, and C-suite executives of Dermatology Private Equity-backed Groups, DPEGs, to build trusting professional relationships
Develop deep understanding of DPEG structures, performance metrics, and educational needs
Develop cross-functional engagement strategy to build the groundwork for launch
Co-create data-driven value proposition to improve patient outcomes
Leadership & Team Management:
Lead, mentor, and manage a team of MSLs, fostering a collaborative, high-performing, and scientifically rigorous culture.
Provide guidance on the development and execution of territory plans, objectives, and key performance indicators (KPIs) for each MSL.
Conduct regular performance evaluations, identify skill gaps, and support MSL development through coaching, training, and career growth opportunities.
Collaborate with the Medical Affairs leadership team to align MSL activities with organizational priorities and strategic initiatives.
Strategic Planning & Execution:
Contribute to the development of MSL tactics in line with corporate and therapeutic area goals.
Drive the execution of MSL tactics within assigned region.
Ensure MSLs are equipped with the latest scientific data and clinical information, and support their integration into both regional and national-level initiatives.
Scientific Exchange & KOL Relationship Management:
Cultivate strong, long-lasting relationships with KOLs, healthcare providers, academic researchers, and key stakeholders through active field engagement in the region.
Serve as a scientific resource and point of contact for KOLs to address inquiries regarding the company’s pipeline, products, and scientific advancements.
Represent the company at scientific congresses, advisory boards, and other relevant forums to enhance scientific and therapeutic understanding.
Cross-Functional Collaboration:
Provide strategic input into the development of clinical trials, publication plans, and other medical activities by leveraging field insights and customer feedback.
Collaborate with the Medical Affairs leadership to ensure appropriate deployment of MSL resources to support clinical, regulatory, and commercial objectives.
Compliance & Reporting:
Ensure all MSL activities are conducted in compliance with regulatory, ethical, and company standards, including GxP (Good Clinical Practice) and HIPAA regulations.
Provide regular updates to MA management on team progress, KOL engagement, and other key initiatives, including metrics on impact and outcomes.
Stay abreast of the competitive landscape and emerging trends in dermatology, rheumatology, and neurology, ensuring MSL activities reflect the latest scientific advancements.
Qualifications:
Education:
o PhD, PharmD, MD, or other advanced degree in a relevant scientific discipline (e.g., Biology, Pharmacology, Medicine).
Experience:
o Minimum of 10 years of experience in Medical Affairs or related scientific roles, with leadership experience in managing a team of MSLs or scientific professionals.
o In-depth knowledge of medical dermatology, including clinical practice, research, and evolving treatment paradigms.
o Proven track record of successful relationship-building with KOLs, HCPs, and key stakeholders within the medical community.
o Experience working in cross-functional teams, with a demonstrated ability to collaborate effectively with commercial, clinical, regulatory, and other business functions.
Skills & Competencies:
o Excellent leadership and team management skills, with the ability to inspire and develop a high-performing team.
o Strong communication, presentation, and interpersonal skills, with the ability to engage effectively with internal and external stakeholders.
o Deep understanding of the pharmaceutical industry, including regulatory and compliance requirements, scientific data dissemination, and product lifecycle management.
o Ability to translate complex scientific information into actionable insights for diverse audiences, including KOLs, healthcare professionals, and internal teams.
o Strong problem-solving, strategic thinking, and decision-making skills.
Travel:
o Willingness to travel extensively (50-75%) as required for KOL engagement, scientific meetings, and team management activities.
Preferred Qualifications:
· Experience in therapeutic areas of medical dermatology.
· Previous experience working in a leadership role within a biopharmaceutical company or a global pharmaceutical organization.
· Familiarity with clinical trial processes, publication planning, and scientific communication in a corporate environment.
The salary range for this position is $220,00 to 250,000 USD annually. This salary range is an estimate, and the actual salary may very based on the Company’s compensation practices degree and background.
This position is primarily remote with travel.
Alumis Inc. is an equal opportunity employer.
Alumis compensation packages include generous stock option grants for all employees as well as an annual bonus program.
Other benefits include:
We are a hard-working, collaborative team on a mission to transform patient’s lives-- and we aspire to elevate, challenge and nurture one another along the way.
Ready to apply?
Apply to AlumisAlumis Inc. is a precision medicines company with the mission to transform the lives of patients with autoimmune diseases. Even with treatment innovations of the last two decades, many patients with immunologic conditions continue to suffer - our goal is to fundamentally change the outcomes for these patients.
We are seeking an experienced Senior Clinical Development Medical Director who will be involved across the full scope of dermatology and autoimmune clinical drug development activities from discovery research through first in human, POC, and Phase 3 studies. The role will include leadership of one or more studies within the portfolio and will work closely with all members of the cross-functional asset team, to apply full clinical knowledge to successfully advance clinical programs as well as the overall asset strategy.
Responsibilities
Qualifications:
The salary range for this position is $325,000 USD to $358,000 USD annually. This salary range is an estimate, and the actual salary may vary based on the Company’s compensation practices.
This position is located in South San Francisco, CA and employees are expected to be onsite Tuesday-Thursday. Open to remote applicants with requirement to be onsite once a month.
Alumis Inc. is an equal opportunity employer.
Alumis compensation packages include generous stock option grants for all employees as well as an annual bonus program.
Other benefits include:
We are a hard-working, collaborative team on a mission to transform patient’s lives-- and we aspire to elevate, challenge and nurture one another along the way.
Ready to apply?
Apply to AlumisAlumis Inc. is a precision medicines company with the mission to transform the lives of patients with autoimmune diseases. Even with treatment innovations of the last two decades, many patients with immunologic conditions continue to suffer - our goal is to fundamentally change the outcomes for these patients.
Position Purpose
The VP of Corporate Communications and Investor Relations will lead the development and implementation of Alumis’ strategic communications initiatives to build identity, reputation and visibility across multiple stakeholders, including media, patient advocacy, potential customers and employees. Reporting to the Chief Finance Officer, the position will work closely with Alumis’ executive and senior leadership, investor relations and other key stakeholders.
Job Description and Key Responsibilities
The Communications position will play a key role generating the internal and external communications strategy for our portfolio of assets and corporate messages to ensure the company's evolving story is communicated effectively. This position will work across functional areas including corporate communications/ PR, commercial, investor relations, clinical, medical affairs, research and HR. They will be the point person for generating, reviewing and deploying communication initiative across various mediums (with subject matter expertise assistance) and responsible for consistently communicating across multiple channels and platforms, including media and scientific conferences.
Specific responsibilities include but are not limited to:
Key Requirements and Qualifications
The salary range for this position is $285,000 USD to $350,000 USD annually. This salary range is an estimate, and the actual salary may vary based on the Company’s compensation practices.
This position is located in South San Francisco, CA and employees are expected to be onsite Tuesday-Thursday.
Alumis Inc. is an equal opportunity employer.
Alumis compensation packages include generous stock option grants for all employees as well as an annual bonus program.
Other benefits include:
We are a hard-working, collaborative team on a mission to transform patient’s lives-- and we aspire to elevate, challenge and nurture one another along the way.
Ready to apply?
Apply to AlumisAlumis Inc. is a precision medicines company with the mission to transform the lives of patients with autoimmune diseases. Even with treatment innovations of the last two decades, many patients with immunologic conditions continue to suffer - our goal is to fundamentally change the outcomes for these patients.
We have recently completed our pivotal trials of envudeucitinib, our second-generation tyk2 inhibitor in moderate to severe plaque psoriasis and expect results from a potentially pivotal Phase 2b trial in SLE in the third quarter of 2026.
As a key member of the Alumis team, you will provide overall leadership for the Medical Affairs function, overseeing Medical Affairs, Field Medical Liaisons, and publications. The position will liaise closely with the clinicians responsible for carrying out Alumis’ clinical studies as well as our commercial group. Applicants should be a “leader/doer” capable of generating strategies and leading cross functionally. This VP, Medical Affairs will report directly to the Chief Medical Officer.
Responsibilities
Lead the Medical Affairs function at Alumis
As a member of the Development Leadership Team, run and continue to build the Medical Affairs function
Education | Experience | Skill Requirements
The salary range for this position is $315,000 USD to $370,000 USD annually. This salary range is an estimate, and the actual salary may vary based on the Company’s compensation practices.
Ready to apply?
Apply to AlumisAlumis Inc. is a precision medicines company with the mission to transform the lives of patients with autoimmune diseases. Even with treatment innovations of the last two decades, many patients with immunologic conditions continue to suffer - our goal is to fundamentally change the outcomes for these patients.
Alumis Inc. is a precision medicines company with the mission to transform the lives of patients with autoimmune diseases. Even with treatment innovations of the last two decades, many patients with immunologic conditions continue to suffer - our goal is to fundamentally change the outcomes for these patients.
Position Summary
Alumis is seeking an experienced Executive Medical Director or Senior Medical Director to lead clinical development strategy and execution for Phase 1 and Phase 2 studies evaluating envudeucitinib and A-005 across new indications identified for expansion of the Alumis pipeline. This high-impact role will be instrumental in shaping the company's clinical development portfolio, from indication selection through proof-of-concept studies, and will serve as a key scientific leader interfacing with internal teams, regulatory authorities, and the external medical community.
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Key Responsibilities
Clinical Development Strategy & Leadership
· Lead the design, planning, and execution of Phase 1 and Phase 2 clinical studies for A-005 and additional pipeline molecules in new therapeutic indications
· Develop and refine clinical development plans, including study synopses, protocols, and integrated development strategies for new indications
· Provide clinical and scientific leadership to cross-functional study teams, ensuring alignment on program goals, timelines, and deliverables
· Collaborate with Translational Medicine and Research teams to evaluate and prioritize new indication opportunities based on scientific rationale, competitive landscape, and unmet medical need
Study Execution & Oversight
· Serve as the Medical Monitor for assigned Phase 1 and 2 studies, ensuring patient safety and scientific integrity
· Oversee medical aspects of study conduct, including safety surveillance, protocol amendments, and data review
· Partner with Clinical Operations, Biostatistics, and Regulatory Affairs to ensure efficient study execution and high-quality data generation
· Lead interactions with Data Safety Monitoring Boards (DSMBs) and provide medical input for safety analyses
Regulatory & External Engagement
· Contribute to regulatory strategy and serve as a clinical representative in interactions with FDA and international regulatory authorities (EMA, PMDA, etc.)
· Prepare and review clinical sections of regulatory submissions, including IND amendments, briefing documents, and meeting packages
· Represent Alumis at scientific conferences, advisory boards, and with Key Opinion Leaders (KOLs) to advance clinical programs and gather external insights
· Build and maintain relationships with investigators, academic collaborators, and the broader medical community
Cross-Functional Collaboration
· Work closely with Translational Sciences, Biomarker, and Pharmacology teams to integrate biomarker strategies into clinical study designs
· Collaborate with Commercial and Medical Affairs teams on disease landscape assessments and indication prioritization
· Provide clinical expertise to support business development activities, including evaluation of potential partnerships or in-licensing opportunities
Team Development
· Mentor and develop junior medical staff, fostering a culture of scientific excellence and collaboration
· Contribute to building Alumis's clinical development capabilities as the organization grows
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Required Qualifications
· MD required; board certification or fellowship training in Rheumatology, Dermatology, or a related specialty strongly preferred
· 10+ years of pharmaceutical/biotechnology industry experience in clinical development, with a significant focus on immunology or autoimmune diseases
· Demonstrated experience leading Phase 1 and Phase 2 clinical studies from design through data readout
· Track record of successful regulatory interactions (FDA, EMA) and experience preparing IND/CTA submissions
· Deep understanding of early clinical development, including dose-finding strategies, biomarker integration, and adaptive trial designs
· Strong scientific acumen with the ability to critically evaluate preclinical and clinical data to inform development strategy
· Experience with JAK/TYK2 inhibitors or related immunomodulatory mechanisms preferred
· Excellent leadership, communication, and interpersonal skills with the ability to influence cross-functional teams in a matrixed environment
· Strategic mindset with demonstrated ability to balance scientific rigor with business objectives
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Preferred Qualifications
· Experience with indication expansion or lifecycle management for immunology assets
· Prior experience at a small or mid-sized biotechnology company; comfort operating in a fast-paced, resource-conscious environment
· Established relationships with KOLs in rheumatology, dermatology, or gastroenterology
· Experience with multiple autoimmune indications (e.g., psoriasis, psoriatic arthritis, lupus, atopic dermatitis, CNS inflammatory and degenerative diseases)
· Familiarity with regulatory pathways for expedited development (Breakthrough Therapy, Fast Track)
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Travel Requirements
Travel required (approximately 20-30%) to support investigator meetings, scientific conferences, regulatory interactions, and site visits.
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The salary range for this position is $300,000 USD to $400,000 USD annually. This salary range is an estimate, and the actual salary may vary based on the Company’s compensation practices.
This position is located in South San Francisco, CA and employees are expected to be onsite Tuesday-Thursday. Remote candidates will be considered on a case-by-case basis.
Alumis Inc. is an equal opportunity employer.
Alumis compensation packages include generous stock option grants for all employees as well as an annual bonus program.
Other benefits include:
We are a hard-working, collaborative team on a mission to transform patient’s lives-- and we aspire to elevate, challenge and nurture one another along the way.
Ready to apply?
Apply to AlumisAlumis Inc. is a precision medicines company with the mission to transform the lives of patients with autoimmune diseases. Even with treatment innovations of the last two decades, many patients with immunologic conditions continue to suffer - our goal is to fundamentally change the outcomes for these patients.
We are seeking an experienced Senior Manager, FP&A – Research & Technical Operations to join our team in a fast-paced, high-growth environment. This position will serve as a strategic finance business partner to the Research and Technical Operations organizations, supporting a growing portfolio of programs and operational priorities. In this role, you will play a critical part in driving planning and forecasting processes, delivering decision support for functional leadership, and assisting the Sr. Director of FP&A in overall planning strategy and execution. This position will also involve close interaction with the Accounting team during month-end close processes.
Responsibilities
Qualifications
Alumis Values
• We Elevate
• We Challenge
• We Nurture
This position is located in South San Francisco, CA and employees are expected to be onsite Tuesday-Thursday.
The salary range for this position is $165,000 USD to $200,000 USD annually. This salary range is an estimate, and the actual salary may vary based on the Company’s compensation practices.
Alumis Inc. is an equal opportunity employer.
Ready to apply?
Apply to AlumisAlumis Inc. is a precision medicines company with the mission to transform the lives of patients with autoimmune diseases. Even with treatment innovations of the last two decades, many patients with immunologic conditions continue to suffer - our goal is to fundamentally change the outcomes for these patients.
Alumis Inc. is a precision medicines company with the mission to transform the lives of patients with autoimmune diseases. Even with treatment innovations of the last two decades, many patients with immunologic conditions continue to suffer – our goal is to fundamentally change the outcomes for these patients.
We are seeking a talented and motivated leader to join our IT team as the Sr. Manager, IT, R&D Applications (Contractor), supporting core business applications for corporate enterprise needs across Development and Research teams including QA, Clinical Operations, Biometrics, Medical Affairs, and Regulatory functions. This position may also assist in supporting initiatives on the enterprise and cross-departmental level. In this role, you will collaborate closely with stakeholders and manage implementation, maintenance, and ongoing support for the SaaS technologies used by these business functions to enhance efficiency and drive business outcomes. The ideal candidate has a solid technical background, is well organized, works independently, and possesses a “can-do” attitude. This role reports to the Director, R&D Business Partner.
Duties & Responsibilities
Qualifications
This position is located in South San Francisco, CA. At this time, we are not considering fully remote applicants.
The salary range for this position is $168,000 – $200,000 USD annually. This salary range is an estimate, and the actual salary may very based on the Company’s compensation practices.
Alumis Inc. is an equal opportunity employer.
Ready to apply?
Apply to AlumisAlumis Inc. is a precision medicines company with the mission to transform the lives of patients with autoimmune diseases. Even with treatment innovations of the last two decades, many patients with immunologic conditions continue to suffer - our goal is to fundamentally change the outcomes for these patients.
Senior Manager, Pharmacovigilance Safety Operations
The Senior Manager, Pharmacovigilance (PV) Safety Operations will report to the Director, PV Safety Operations. This role will play a critical role in ensuring timely reporting, processing, and submission of ICSRs from ongoing clinical trials and post-marketing trials. This role involves overseeing case processing vendors, managing ICSR process, collaborating with cross-functional teams study execution teams, assisting with inspection readiness activities, all while compliance with regulatory requirements.
Essential Responsibilities
ICSR Operational Excellence/Vendor Oversight
• Provide end-to-end operational oversight of ICSR intake, processing, follow-up, quality control, and submissions performed by our outsourced PV vendors.
• Ensure accurate and timely processing of ICSR to ensure accuracy and consistency, and compliance with Alumis standard operating procedures (SOP) and PV system expectations.
• Lead the development and maintenance of safety management plans and submission tracking systems.
• Support the development and maintenance of SOPs.
• Coordinate internal medical review activities in collaboration with medical case reviewers.
• Monitor case flow to ensure timely exchange for submissions.
• Review operational trends and quality indicators to proactively identify risks and drive corrective actions.
• Collaborate with clinical operations, data management, and PV teams to perform database reconciliation for clinical trials.
• Track the submission of safety reports to regulatory authorities and ensure compliance with country or regional submission deadlines.
• Ensure all safety operations are conducted in compliance with FDA, ICH, and other relevant regulatory guidelines.
Cross-Functional Collaboration
• Work closely with clinical development, regulatory, and quality assurance teams to align safety operations with overall study objectives and ensure regulatory compliance.
• Assist in the preparation of new clinical trials study start up activities such as review Safety sections of clinical trial protocols, Informed Consent Forms, clinical database configurations, including User Acceptance Testing and Safety Case Report Forms.
• Collaborate with Safety Surveillance and assist in the preparation of surveillance meeting materials from safety operation perspective and assist with the development of aggregate reports, such as Development Safety Update Report (DSUR), Periodic Adverse Drug Experience Report (PADER), Periodic Benefit-Risk Evaluation Report (PBRER) by performing various activities such as quality control.
• Contribute to PV system audit-readiness and support inspections activities.
The Ideal Candidate
• Bachelor’s degree in life sciences, pharmacy, or a related field.
• Minimum of 7+ years of experience in safety operations in the biopharmaceutical industry.
• Experience with early and late-stage clinical trials (Phase 3) and post-marketing are highly desirable.
• Experience with device safety reporting and regulatory inspections is a plus.
• Strong knowledge of regulatory requirements (e.g., FDA, ICH guidelines) and industry standards related to drug safety and case processing.
• Demonstrated experience in vendor oversight, submission tracking, and quality control.
• Excellent organizational, analytical, and communication skills.
• Ability to work independently and collaboratively in a fast-paced environment and manage multiple projects simultaneously.
• Leads self by managing and executing own work to deliver results that contribute to accomplishing common department goals
• Proficiency in safety databases and software tools (e.g., Oracle Argus, ARISg, MedDRA).
This role is anchored at our South San Francisco, CA headquarters, with an expectation to be onsite Tuesday through Thursday. While we prefer local candidates, remote applicants based in the Pacific Time Zone will be considered on a case-by-case basis with the ability to travel to HQ approximately once per month, or as business needs require.
The salary range for this position is $170,000 USD to $200,000 USD annually. This salary range is an estimate, and the actual salary may vary based on the Company’s compensation practices.
Ready to apply?
Apply to AlumisAlumis Inc. is a precision medicines company with the mission to transform the lives of patients with autoimmune diseases. Even with treatment innovations of the last two decades, many patients with immunologic conditions continue to suffer - our goal is to fundamentally change the outcomes for these patients.
We are seeking an experienced Senior Medical Director in Clinical Development who will be involved across the full scope of rheumatology and autoimmune clinical drug development activities from discovery research through first in human, POC, and Phase 3 studies. The role will include leadership of one or more studies within the portfolio and will work closely with all members of the cross-functional asset team, to apply full clinical knowledge to successfully advance clinical programs as well as the overall asset strategy.
Principal Responsibilities
Primary Goals During the opening months on the job, this Senior Medical Director will be expected to focus on the following objectives:
1. Earn the full trust and respect of key internal and external stakeholders by establishing a reputation as a strategic and highly productive partner.
2. Provide hands-on leadership, apply knowledge and expertise, and partner seamlessly with the operations team to help make LUMUS thrive.
3. Focus on improving and maintaining study data quality, including cross-referencing of the main efficacy endpoints.
Candidate Requirements
The salary range for this position is $300,000 USD to $358,000 USD annually. This salary range is an estimate, and the actual salary may vary based on the Company’s compensation practices.
This position is located in South San Francisco, CA and employees are expected to be onsite Tuesday-Thursday. Open to remote applicants with requirement to be onsite once a month.
Alumis Inc. is an equal opportunity employer.
Alumis compensation packages include generous stock option grants for all employees as well as an annual bonus program.
Other benefits include:
We are a hard-working, collaborative team on a mission to transform patient’s lives-- and we aspire to elevate, challenge and nurture one another along the way.
Ready to apply?
Apply to AlumisCookies & analytics
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