At GSK Barnard Castle, we are a key manufacturing site supporting a diverse portfolio of medicines supplied to over 130 markets globally. We continue to invest significantly in state-of-the-art equipment and technologies to support new product introductions and future growth.

We create a place where people can grow, be their best, be safe, and feel welcome, valued and included. We offer a competitive salary, an annual bonus based on company performance, healthcare and wellbeing programmes, pension plan membership, and shares and savings programme.

Discover more about our company wide benefits and life at GSK on our webpage Life at GSK | GSK

Successful applicants will join our Sterile Production Team and may be appointed into either an Aseptic Operator or Manufacturing Operator position depending on skills, experience and business requirements.

You will be required to work a 24/7 shift pattern.

In this role you will…

Manufacturing Operations:

• Manufacturing biopharmaceuticals and oligonucleotides using disposable technologies.
• Dispensing buffer excipients and preparing manufacturing materials.
• Performing analytical testing, including pH, density and osmolarity measurements.
• Receiving, handling and removing materials from controlled temperature storage areas.
• Manufacturing multiple products, including new product introductions at various lifecycle stages.
• Supporting filling operations, including component processing, finished product processing and in-process control checks.

Aseptic Operations:

• Qualifying and maintaining a sterile operating licence.
• Setting up and operating aseptic filling isolators.
• Performing glove integrity testing, machine cleaning, machine builds and VHP cycles.
• Conducting sterile interventions, environmental monitoring and sterile transfers.
• Operating sterile interfaces including ISS and RTP/IDC ports.
• Performing filter integrity testing, including PUPSIT and PUIT where applicable.
• Working within cleanroom environments while demonstrating excellent aseptic behaviours.

General Responsibilities:

• Using digital manufacturing and automation systems such as MES, PCS7 and other site systems.
• Preparing equipment and components through parts washing and autoclaving processes.
• Completing documentation accurately and in a timely manner.
• Working collaboratively with cross-functional teams including MSAT, Engineering, Quality, Microbiology and R&D.
• Participating in troubleshooting activities and continuous improvement initiatives.
• Demonstrating the GSK values of Transparency, Respect, Integrity and Patient Focus.
• Meeting expectations of teamwork, accountability, development and courage.

Why you? 

Basic Qualifications & Skills:

We are looking for professionals with these required skills to achieve our goals:

• A minimum of 5 GCSEs (or equivalent) or relevant pharmaceutical manufacturing experience.
• Experience working within a pharmaceutical manufacturing environment.
• Experience using digital systems and platforms.
• Experience working in a Good Manufacturing Practice (GMP) environment and understanding its importance.
• Experience troubleshooting operational issues and contributing to continuous improvement activities.
• The flexibility and willingness to work the defined shift patterns.

Preferred Qualifications:

If you have the following characteristics, it would be a plus:

• Previous sterile manufacturing experience.
• Previous aseptic isolator experience.
• Current or previous sterile area licence holder.
• Experience working in cleanroom environments.
• Experience supporting sterile filling operations.

Closing Date for Applications: 29th September 2026 (COB)

Please take a copy of the Job Description, as this will not be available post closure of the advert.

When applying for this role, please use the ‘cover letter’ of the online application or your CV to describe how you meet the competencies for this role, as outlined in the job requirements above. The information that you have provided in your cover letter and CV will be used to assess your application.

We are addressing gender equality at all levels within our organisation, we also remain committed to improving ethnic diversity within GSK and recruiting and developing talent that mirrors the communities in which we work. With support from our Global Disability Council and our employee resource group, the Disability Confidence Network, we are working hard to create an inclusive workplace.

We want GSK to be somewhere everyone can feel a sense of belonging and thrive. Our success absolutely depends on our people.

Skills

Why GSK?

Uniting science, technology and talent to get ahead of disease together.

GSK is a global biopharma company with a purpose to unite science, technology and talent to get ahead of disease together. We aim to positively impact the health of 2.5 billion people by the end of the decade, as a successful, growing company where people can thrive. We get ahead of disease by preventing and treating it with innovation in specialty medicines and vaccines. We focus on four therapeutic areas: respiratory, immunology and inflammation; oncology; HIV; and infectious diseases – to impact health at scale.

People and patients around the world count on the medicines and vaccines we make, so we’re committed to creating an environment where our people can thrive and focus on what matters most. Our culture of being ambitious for patients, accountable for impact and doing the right thing is the foundation for how, together, we deliver for patients, shareholders and our people.

GSK is an Equal Opportunity Employer. This ensures that all qualified applicants will receive equal consideration for employment without regard to race, color, religion, sex (including pregnancy, gender identity, and sexual orientation), parental status, national origin, age, disability, genetic information (including family medical history), military service or any basis prohibited under federal, state or local law.

We believe in an agile working culture for all our roles. If flexibility is important to you, we encourage you to explore with our hiring team what the opportunities are.

Should you require any adjustments to our process to assist you in demonstrating your strengths and capabilities contact us at [email protected] where you can also request a call.

Please note should your enquiry not relate to adjustments, we will not be able to support you through these channels. However, we have created a  Recruitment FAQ guide. Click the link where you will find answers to multiple questions we receive

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