ICON is a global healthcare intelligence and clinical research organisation united by a mission to bring new medicines and treatments to patients faster.

As a values-driven organisation, integrity, collaboration, agility, and inclusion are at the heart of how we work and interact with each other, customers, patients and suppliers.

Senior Clinical Trial Manager

We are currently seeking a Senior Clinical Trial Manager to join our diverse and dynamic team at ICON. In this critical leadership role, you will oversee the operational delivery of clinical trials from study start-up through closeout, ensuring quality, compliance, and execution against study timelines and objectives.

As the clinical operations lead, you will work cross-functionally with sponsors, investigators, vendors, and internal stakeholders to drive successful study outcomes while identifying and mitigating risks throughout the trial lifecycle.

What you will be doing

• Lead the operational delivery of assigned clinical trials, ensuring milestones, timelines, budget expectations, and quality standards are achieved.
• Drive study start-up activities, site activation, enrollment strategies, and study execution through database lock.
• Provide oversight of study progress, monitoring activities, clinical metrics, and site performance.
• Develop and implement effective study oversight plans, monitoring strategies, and risk mitigation approaches.
• Identify operational challenges and proactively implement solutions to ensure successful study delivery.
• Build and maintain strong relationships with sponsors, investigators, vendors, and cross-functional stakeholders.
• Review study performance metrics and provide regular status updates and reporting.
• Support, mentor, and collaborate with Clinical Research Associates (CRAs) and other study team members.
• Ensure all clinical trial activities comply with protocol requirements, ICH-GCP guidelines, and applicable regulatory requirements.

Your Profile

• Bachelor's degree in Life Sciences, Health Sciences, Nursing, Pharmacy, or another relevant scientific discipline, or an equivalent combination of education and experience.
• Significant Clinical Trial Management experience within a CRO (preferred), pharmaceutical, or biotechnology environment.
• Demonstrated ability to successfully lead and deliver clinical studies from start-up through closeout.
• Strong understanding of clinical trial operations, ICH-GCP, and applicable regulatory requirements.
• Experience managing study timelines, budgets, vendors, and cross-functional stakeholders.
• Proven ability to identify risks, solve complex operational challenges, and drive study execution.
• Prior monitoring experience preferred.
• Experience managing global and/or complex clinical trials preferred.
• Ability to travel up to 20%.

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Employment with ICON is contingent upon having the legal right to work in the country where the role is based.

Rewards & Benefits

ICON offers a competitive and comprehensive total rewards package designed to support your health, wellbeing, and career development.

Benefits may include:

• Competitive base salary and performance related incentives
• Health and wellbeing programmes including medical, dental, and vision coverage where applicable
• Retirement and pension plans
• Life assurance and disability coverage
• Employee assistance programmes and wellbeing resources
• Learning and development opportunities through structured training and career pathways

Benefits may vary depending on role and location.

Visit our careers site to read more about the benefits ICON offers.

Inclusion and Accessibility

ICON is an equal opportunity employer. We are committed to building an inclusive and accessible workplace where everyone feels valued and supported.

If you require reasonable accommodations during the recruitment process, please let us know or submit a request here.

Are you a current ICON Employee? Please click here to apply