Jobs › Companies › Korrobio › Research Associate/Senior Research Associate, Oligonucleotide Chemistry

Sobre esta vaga de Research Associate/Senior Research Associate, Oligonucleotide Chemistry na Korrobio

Korrobio · Presencial · 60 First St, Cambridge, MA 02141

Korro is a biopharmaceutical company focused on developing a new class of genetic medicines for both rare and highly prevalent diseases using its proprietary RNA editing platform. Korro is generating a portfolio of differentiated programs that are designed to harness the body’s natural RNA editing process to effect a precise yet transient single base edit. By editing RNA instead of DNA, Korro is expanding the reach of genetic medicines by delivering additional precision and tunability, which has the potential for increased specificity and improved long-term tolerability. Using an oligonucleotide-based approach, Korro expects to bring its medicines to patients by leveraging its proprietary platform with precedented delivery modalities, manufacturing know-how, and established regulatory pathways of approved oligonucleotide drugs. Korro’s lead program is for Urea Cycle Disorders. Korro is based in Cambridge, Massachusetts. For more information, visit korrobio.com.  

We are collaborative and united by a common mission. We are building a company with extraordinary people with an audacious vision to create transformative genetic medicines for prevalent diseases. Our values - Rewrite the future, On the Cutting Edge, Better Together, Dynamically Different, Kindness and Integrity form the fabric of the organization. They are reinforced daily and serve as key dimensions in the hiring process to help us ensure that Korro is a magnet for outstanding talent and a great place to work. Join us as we redefine what's possible in genetic medicine and work to make a lasting impact on human health. 

Position Summary

Korro Bio is seeking a motivated, detail-oriented Research Associate to join our Oligonucleotide Chemistry team. The successful candidate will synthesize, purify, and characterize chemically modified oligonucleotides and conjugates on automated platforms, supplying oligonucleotides for screening across Korro’s discovery programs. This is a hands-on, lab-based role suited to someone with practical oligonucleotide synthesis experience who takes ownership of instrument operation and maintenance, keeps meticulous records, and communicates results clearly to the team and cross-functionally. This position reports to Scientist II and is based on-site in Cambridge, MA.

Key Responsibilities

  • Execute solid-phase synthesis, purification, and downstream processing of chemically modified oligonucleotides and oligonucleotides conjugates at different scales using modern automated oligo synthesis platforms
  • Operate, maintain & troubleshoot equipment for oligonucleotide synthesis (Mermade 12 and 192), purification, desalting and lyophilization
  • Ability to cross-train with other synthesis scales and instrumentation
  • Maintain inventory of chemicals and amidites for oligonucleotide synthesis
  • Perform in-process and final analytics of oligonucleotide samples as needed
  • Track progress, analyze, organize, and present data to team and cross-functionally
  • Maintain a well-documented electronic laboratory notebook
  • Actively participate in training activities and provide training to others as needed
  • Author and review SOPs and technical reports 
  • Required Qualifications

  • BS/MS with 1+ years experience in Chemistry, Biochemistry, Biotechnology, or related field  
  • Hands-on experience in the synthesis, purification, and analysis of oligonucleotides 
  • Experience with high throughput synthesizers such as Mermade 192 is a plus
  • Strong laboratory skills and experience in handling, troubleshooting and routine maintenance of lab equipment including automated synthesis platforms, HPLC and LC-MS etc. 
  • High degree of flexibility and self-motivation in a fast-paced work environment with excellent organizational skills, ability to prioritize appropriately and meet deadlines. 
  • Excellent interpersonal, communication and presentation skills. 
  • Detail-oriented and excellent problem-solving abilities.

  • Korro Bio offers a competitive total rewards package, including equity-based compensation and comprehensive benefits: medical, dental, and vision coverage; 401(k) retirement plan; life insurance; dependent care flexible spending account; company-funded health savings account; and complimentary parking or a MBTA commuter pass.

    Pronto para se candidatar à Korrobio?
    Candidatar-se à Korrobio

    Vagas semelhantes

    WC
    Clinical Research Associate II
    Worldwide Clinical Trials
    ⚡ Candidate-se cedo Buenos Aires, Argentina Presencial
    ● Nova 👁 Vista ✓ Candidatada há 2h
    AC
    Senior Research Associate, Evidence Synthesis
    American Cancer Society
    ⚡ Candidate-se cedo Portland, Oregon Presencial
    ● Nova 👁 Vista ✓ Candidatada há 2h
    Parexel
    Clinical Research Associate - All locations- FSP
    Parexel
    ⚡ Candidate-se cedo United States - Remote · local restrito
    ● Nova 👁 Vista ✓ Candidatada há 2h
    MS
    Equity Research – Associate, SMID Cap Biotech (New York)
    Morgan Stanley
    ⚡ Candidate-se cedo New York, New York, United Sta... Presencial $150,000–$200,000
    ● Nova 👁 Vista ✓ Candidatada há 4h
    TF
    FSP Experienced Clinical Research Associate (CRA II/Sr. CRA I) - Oncology - Respiratory - Cardiovascular - US West
    Thermo Fisher Scientific
    ⚡ Candidate-se cedo Remote, Oregon, USA · local restrito $72,000–$120,000
    ● Nova 👁 Vista ✓ Candidatada há 5h
    Financial Technology Partners
    Equity Research Associate – FinTech
    Financial Technology Partners
    ⚡ Candidate-se cedo San Francisco, CA or New York... Presencial
    ● Nova 👁 Vista ✓ Candidatada há 7h
    Delfidiagnostics
    Senior Research Associate, Assay Development - PM Shift (Contract)
    Delfidiagnostics
    ⚡ Candidate-se cedo Palo Alto, CA Presencial
    ● Nova 👁 Vista ✓ Candidatada há 9h
    TF
    Senior Clinical Research Associate (Melbourne or Sydney)
    Thermo Fisher Scientific
    ⚡ Candidate-se cedo Melbourne, Australia Presencial
    ● Nova 👁 Vista ✓ Candidatada há 12h
    TF
    Senior Clinical Research Associate II (Perth or Adelaide)
    Thermo Fisher Scientific
    ⚡ Candidate-se cedo West Australia, Australia Presencial
    ● Nova 👁 Vista ✓ Candidatada há 12h

    Cadastre-se para receber sugestões sob medida com base nas vagas que você abre e nas buscas que você salva.

    Mais vagas na Korrobio

    Ver todas as vagas na Korrobio →

    Candidatar-se agora
    🤖

    Opa — calma aí

    A JobsRadar foi feita para pessoas de verdade passando por um momento difícil na busca por emprego — não para requisições automatizadas. Você está clicando rápido demais e agora está temporariamente bloqueado.

    Volte mais tarde. Se você está mesmo procurando emprego, estamos com você — apenas aja como um ser humano.

    Catch your next role the second it’s posted.

    Create a free account and we’ll watch the boards for you — the instant a job matches your search, it lands in your inbox or Telegram. No digging, no refreshing.

    Create free account

    Free forever · takes 30 seconds · already have one?

    Ganhe vantagem na sua busca por emprego.

    Entre no nosso canal do Telegram para o que ajuda você a conseguir a vaga — referências salariais, o pulso semanal do mercado e avisos de novos recursos. Sem spam, só sinal.

    Entre no canal — é grátis