All active System Administrator roles based in Cambridge.
Pick a job to read the details
Tap any role on the left — its description and apply link will open here.
Share this job
Amylyx has an audacious mission to usher in a new era for treating diseases with high unmet needs. Where others see challenges, we see opportunities that we pursue with urgency, rigorous science, and unwavering commitment to the communities we serve. We are a clinical-stage company currently focused on post-bariatric hypoglycemia (PBH), Wolfram syndrome, and amyotrophic lateral sclerosis (ALS).
Our mission is powered by our people. Our core values – be audacious, be curious, be authentic, be engaged, and be accountable – creating a culture of caring. Amylyx has assembled an experienced team ready to take action because the communities we serve have no time to wait. If you share our passion and are determined to tackle some of medicine’s toughest problems, we encourage you to read the opportunity below and apply.
The Opportunity
We are seeking an experienced Associate Director, Contracts to refine and scale our contracting operations and review as we prepare for a potential drug launch. This role will own the full contract lifecycle process—from intake and template selection through, execution and post‑execution management, including negotiating certain agreements independently. This is a highly visible, customer‑service‑oriented role that will serve as the internal subject‑matter expert and trainer for Amylyx’s contract lifecycle management system (CLMS). The ideal candidate will have a strong background in contract management and negotiation within the life sciences, biotech, or pharmaceutical industry and thrive in a fast‑moving, evolving environment.
Responsibilities
Contract Management & Operations
Contract Review & Negotiation
Required Qualifications
Preferred Qualifications
Work Location and Conditions
Compensation
The pay range posted below represents our good faith estimate of compensation for this role, based on market data and internal benchmarks. The final offer may vary depending on a candidate’s experience, skills, and qualifications, as well as considerations of internal equity.
To stay connected with us, follow Amylyx Pharmaceuticals on LinkedIn.
To return to our website please click here.
Amylyx Pharmaceuticals is an Equal Opportunity Employer that does not discriminate on the basis of actual or perceived race, color, creed, religion, national origin, ancestry, citizenship status, age, sex or gender (including pregnancy, childbirth, pregnancy-related conditions, and lactation), gender identity or expression (including transgender status), sexual orientation, marital status, military service and veteran status, physical or mental disability, genetic information, or any other characteristic protected by applicable federal, state, or local laws and ordinances. Amylyx’s management team is dedicated to this policy with respect to recruitment, hiring, placement, promotion, transfer, training, compensation, benefits, employee activities, access to facilities and programs, and general treatment during employment. Accommodations are available for candidates who require them in our selection process. If you need an accommodation, please let your Amylyx Talent Acquisition contact know.
It is unlawful in Massachusetts to require or administer a lie detector test as a condition of employment or continued employment. An employer who violates this law shall be subject to criminal penalties and civil liability.
Ready to apply?
Apply to Amylyx Pharmaceuticals
Share this job
Who We Are
Flagship Pioneering is a biotechnology company that invents and builds platform companies that change the world. We bring together the greatest scientific minds with entrepreneurial company builders and assemble the capital to allow them to take courageous leaps. Those big leaps in human health and sustainability exponentially accelerate scientific progress in areas ranging from cancer detection and treatment to nature-positive agriculture.
What sets Flagship apart is our ability to advance biotechnology by uniting life science innovation, company creation, and capital investment under one roof in a way that is largely without precedent. Our scientific founders, entrepreneurial leaders, and professional capital managers are each aligned around an institutionalized process that enables us to innovate and transform for the benefit of people and planet.
Many of the companies Flagship has founded have addressed humanity’s most urgent challenges: vaccinating billions of people against COVID-19, curing intractable diseases, improving human health, preempting illness, and feeding the world by improving the resiliency and sustainability of agriculture.
Flagship has been recognized twice on FORTUNE’s “Change the World” list, an annual ranking of companies that have made a positive social and environmental impact through activities that are part of their core business strategies, and has been twice named to Fast Company’s annual list of the World’s Most Innovative Companies.
Our Lab IT and Research Systems teams enable scientific discovery across the Flagship ecosystem through reliable, scalable, and secure technology solutions that support scientists at the bench and in silico. We collaborate closely with our research teams to ensure their tools, systems, and environments are optimized for productivity, reproducibility, and innovation.
IT Systems Administrator Cambridge, MA (In-Person)
Position Summary:
The IT Infrastructure Operations & Architecture (IT IO&A) team is responsible for IT Infrastructure from network port to cloud, and the devices in between. The IT IO&A team is seeking an experienced Systems Administrator who is able to bridge between help desk services and technical subject matter experts in Cloud, Network, and M365. The ITIO Systems Administrator will be the subject matter expert in all thing’s endpoint management. Duties range from helpdesk escalation support to automation and engineering designed to improve service delivery. This role is intended to interface with all the domains ITIO is responsible for including Scientific Cloud, Networking, M365, and Identity and Access Management.
What You'll Do:
What We're Looking For:
Nice to Have:
Physical Requirements
Work Environment
This position operates in a professional office environment and may also require work in telecommunications rooms, data centers, and other technical spaces.
Physical Requirements
We recognize that great candidates often bring unique strengths without fulfilling every qualification. If you have some of the experience listed above but not all, please apply anyway. We are dedicated to building diverse and inclusive teams and look forward to learning more about your background and interest in Flagship.
Recruitment & Staffing Agencies: Flagship Pioneering and its affiliated Flagship Lab companies (collectively, “FSP”) do not accept unsolicited resumes from any source other than candidates. The submission of unsolicited resumes by recruitment or staffing agencies to FSP or its employees is strictly prohibited unless contacted directly by Flagship Pioneering’s internal Talent Acquisition team. Any resume submitted by an agency in the absence of a signed agreement will automatically become the property of FSP, and FSP will not owe any referral or other fees with respect thereto.
#LI-NM1
The salary range for this role is $76,000 - $104,500. Compensation for the role will depend on a number of factors, including a candidate’s qualifications, skills, competencies, and experience. Flagship Pioneering currently offers healthcare coverage, annual incentive program, retirement benefits and a broad range of other benefits. Compensation and benefits information is based on Flagship Pioneering's good faith estimate as of the date of publication and may be modified in the future.
Privacy Notice for Applicants: When you apply for a role at Flagship Pioneering or one of its portfolio companies, we collect and use personal information you provide (such as your name, contact details, work history, and application materials) to evaluate your application, communicate with you, and comply with legal obligations. Your application data is processed through Greenhouse, our applicant tracking system, and may also be reviewed using AI-assisted screening tools. We do not sell your personal information. California residents have rights under the CCPA/CPRA including to know, delete, and opt out of the sharing of their personal information. If you are located in the EU or UK, we process your data under GDPR and you have rights to access, rectify, and erase your data. To exercise your rights or for questions, contact privacy@flagshippioneering.com.
Ready to apply?
Apply to Flagship Pioneering, Inc.
Share this job
Flagship Pioneering is a scientific innovation engine that invents and builds companies that change the world. We bring together the greatest scientific minds with entrepreneurial company builders and assemble the capital to allow them to take courageous leaps in human health, sustainability, and beyond.
What sets Flagship apart is our ability to advance biotechnology by uniting life science innovation, company creation, and capital investment under one roof in a way that is largely without precedent. Our team of scientists, entrepreneurial leaders, and professional capital managers are each aligned around an institutionalized process that enables us to innovate and create breakthroughs for the benefit of people and planet.
Many of the companies Flagship has founded have addressed humanity’s most urgent challenges: vaccinating billions of people against COVID-19, curing intractable diseases, improving human health, preempting illness, and feeding the world by improving the resiliency and sustainability of agriculture.
Flagship has been recognized twice on FORTUNE’s “Change the World” list, an annual ranking of companies that have made a positive social and environmental impact through activities that are part of their core business strategies, and has been named four times to Fast Company’s annual list of the World’s Most Innovative Companies.
We are seeking a Contracts System Manager to serve as the primary owner and administrator of Flagship's Contract Lifecycle Management (CLM) and procurement systems. This individual will be responsible for system configuration, optimization, user support, training, and cross-functional collaboration to ensure the Legal, Procurement, and Finance teams can efficiently manage contracts across Flagship and its portfolio companies. The role requires significant interpersonal engagement—building trusted relationships across business units, influencing stakeholders to adopt new processes, and exercising judgment in navigating competing priorities that require human insight and contextual understanding.
The ideal candidate will have 3–5 years of experience administering CLM platforms (Cobblestone experience strongly preferred), a solid understanding of procurement workflows, and the ability to translate business requirements into technical system configurations. This role requires strong stakeholder engagement skills, attention to detail, and comfort working in a fast-paced, high-volume environment.
This is a great opportunity to join a company at the forefront of innovation in technology and science. We are looking for a self-motivated, entrepreneurial, and kind individual who works hard but doesn't take themselves too seriously. The team you would be joining is tight-knit and committed to helping one another succeed.
System Administration & Configuration
Integration & Technical Operations
User Support & Training
Cross-Functional Collaboration & Stakeholder Engagement
Reporting & Analytics
Compliance & Process Improvement
We seek individuals who reflect Flagship's culture of fearless exploration, entrepreneurial thinking, and collaborative impact. You thrive in environments that require creative problem solving, strong ownership, and alignment with mission-driven outcomes.
Flagship Pioneering is an Equal Opportunity Employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, national origin, disability, or protected veteran status.
#LI-NM1
The salary range for this role is $108,000 - $148,000. Compensation for the role will depend on a number of factors, including a candidate’s qualifications, skills, competencies, and experience. Flagship Pioneering currently offers healthcare coverage, annual incentive program, retirement benefits and a broad range of other benefits. Compensation and benefits information is based on Flagship Pioneering's good faith estimate as of the date of publication and may be modified in the future.
Privacy Notice for Applicants: When you apply for a role at Flagship Pioneering or one of its portfolio companies, we collect and use personal information you provide (such as your name, contact details, work history, and application materials) to evaluate your application, communicate with you, and comply with legal obligations. Your application data is processed through Greenhouse, our applicant tracking system, and may also be reviewed using AI-assisted screening tools. We do not sell your personal information. California residents have rights under the CCPA/CPRA including to know, delete, and opt out of the sharing of their personal information. If you are located in the EU or UK, we process your data under GDPR and you have rights to access, rectify, and erase your data. To exercise your rights or for questions, contact privacy@flagshippioneering.com.
Ready to apply?
Apply to Flagship Pioneering, Inc.
Cookies & analytics
This site uses cookies from third-party services to deliver its features and to analyze traffic.