About Alltrna 

Alltrna is the first clinical-stage biotech company advancing tRNA medicines to address shared disease-causing mutations across many indications. The company’s initial therapeutic programs are designed to restore full-length protein production in diseases caused by premature termination codons (PTCs), collectively referred to as Stop Codon Disease, which affect approximately 10% of people with a rare genetic disease.

Alltrna’s lead program, AP003, is a chemically modified, engineered tRNA oligonucleotide encapsulated in a clinically validated, liver-directed lipid nanoparticle. AP003 is being developed for the arginine-to-TGA (Arg-TGA) PTC in patients with liver Stop Codon Disease, including phenylketonuria, organic acidemias, and urea cycle disorders. Founded in 2018 by Flagship Pioneering, Alltrna has built an integrated platform to design, optimize, and deliver engineered tRNA therapeutics. 

For more information, visit www.alltrna.com

Sr. Director Program Management & Business Operations

Position Summary:

Alltrna is seeking a talented and highly motivated Sr. Director Program Management and Business Operations, reporting to the President & CFO.  The successful candidate is a proven leader with extensive experience in leading research and early drug development program teams from research through the clinic with a particular initial focus on IND enabling and early/mid-stage clinical development. The candidate will be a member of the Company’s Leadership Team and will serve as Chief of Staff to the team to drive collaboration, cross-functional clarity, alignment and execution on key priorities and initiatives required to meet the goals of the organization.

Key Responsibilities:

Program Management:

• Work closely with the Chief Medical Officer to lead the program team for the Company’s lead program, AP003, and future programs instilling a culture of scientific rigor, open debate, collaborative teamwork, sense of urgency and accountability
• Possess a comprehensive understanding of the drug discovery process to guide program teams to define the key scientific questions, program strategy and objectives, translating these into optimal deliverables, cross-functional plans, timelines and budgets
• Identify bottlenecks, risks, issues and proactively develop appropriate mitigation proposals with input from team members
• Ensure all key decisions are identified and properly assessed as to their impact and alternative scenarios developed and evaluated, where appropriate
• Work closely with finance and functional teams to develop the operational plans to support program activities with realistic timelines, budget, and resource planning and monitor performance against plans
• Interface with and drive collaboration between the various functional teams and with the Leadership Team on program-related matters.
• Be the key accountable person for communicating matters related to the programs to management including strategy, work product, updates and issues; producing the one “source of truth” for program-related topics and timelines
• Point person for alliance management and coordination, as needed
• Lead and/or manage strategic or platform development projects as required and collaborate with Chief Scientific Officer and Research Leadership Team to coordinate relevant content for quarterly business review meetings

Operations:

• Collaborate with Leadership Team in development of strategic plans, company goals, long-range planning assumptions, portfolio-level reports and analyses to support business processes and strategic discussions
• Develop and deliver impactful presentations that effectively distill complex issues to the critical points and lead to increased understanding and optimized strategic planning & decision-making

• Prepare strategic communications utilizing a clear understanding of the business strategy and issues; develop and maintain consistent, relevant content for use in executive-level communications and to further organizational and business goals

• Lead the Scientific Communications process, working with the Scientific Communications Committee

• Manage schedule, agenda, and content for Leadership Team, Board of Directors and Town Hall meetings

• Proactively seek opportunities for organizational improvements (e.g. team structure, processes, communication, etc.)

Other:

• Support CEO / LT with partnership discussions and negotiations, including background research, preparation of presentation materials, supporting diligence activities, participating in analysis of terms, etc.
• Assist in mapping competitive landscape and proactively identify potential and emerging competitive threats and opportunities
• Promote strategic discussions on external trends, competitor strategies, and potential disruptors, and translate these into strategic choices/ recommendations
• Collect insights and intelligence from a variety of sources including literature searches, reviewing analyst research, KOL and patient group interactions, etc.

Key Competencies:

• This is a highly visible leadership role that requires exceptional interpersonal and communication skills, creative thinking, and early drug development experience that allows one to recognize opportunities/challenges and modify strategy accordingly
• The individual will need to have self-confidence and poise to manage complicated programs and projects with multiple stakeholders

• The individual will need a sense of urgency and can-do attitude to develop therapies for patients with significant unmet medical needs

Minimum Qualifications:

• BS/MS Degree in a scientific discipline, ideally life science or chemistry.
• At least 15 years relevant experience in pharma or biotech drug discovery and development, as well as a comprehensive understanding of drug discovery (preclinical and clinical).
• 10+ years of Program Management experience, preferably in early-stage drug discovery and development.
• Experience in the development of advanced therapies to treat rare genetic disease is a plus
• Demonstrated experience leading cross-functional teams; strong interpersonal and communication skills
• Scientific curiosity and passion for discovering new, innovative medicines.
• Openness to embrace new technologies and digital approaches in drug discovery
• Proven track record in driving successful, collaborative drug discovery teams.

The salary range for this role is $213,000 - $280,500. Compensation for the role will depend on a number of factors, including a candidate’s qualifications, skills, competencies, and experience. Alltrna currently offers healthcare coverage, annual incentive program, retirement benefits and a broad range of other benefits. Compensation and benefits information is based on Alltrna's good faith estimate as of the date of publication and may be modified in the future.

About Alltrna 

Alltrna is the first clinical-stage biotech company advancing tRNA medicines to address shared disease-causing mutations across many indications. The company’s initial therapeutic programs are designed to restore full-length protein production in diseases caused by premature termination codons (PTCs), collectively referred to as Stop Codon Disease, which affect approximately 10% of people with a rare genetic disease.

Alltrna’s lead program, AP003, is a chemically modified, engineered tRNA oligonucleotide encapsulated in a clinically validated, liver-directed lipid nanoparticle. AP003 is being developed for the arginine-to-TGA (Arg-TGA) PTC in patients with liver Stop Codon Disease, including phenylketonuria, organic acidemias, and urea cycle disorders. Founded in 2018 by Flagship Pioneering, Alltrna has built an integrated platform to design, optimize, and deliver engineered tRNA therapeutics. 

For more information, visit www.alltrna.com

Sr. Director Program Management & Business Operations

Position Summary:

Alltrna is seeking a talented and highly motivated Sr. Director Program Management and Business Operations, reporting to the President & CFO.  The successful candidate is a proven leader with extensive experience in leading research and early drug development program teams from research through the clinic with a particular initial focus on IND enabling and early/mid-stage clinical development. The candidate will be a member of the Company’s Leadership Team and will serve as Chief of Staff to the team to drive collaboration, cross-functional clarity, alignment and execution on key priorities and initiatives required to meet the goals of the organization.

Key Responsibilities:

Program Management:

• Work closely with the Chief Medical Officer to lead the program team for the Company’s lead program, AP003, and future programs instilling a culture of scientific rigor, open debate, collaborative teamwork, sense of urgency and accountability
• Possess a comprehensive understanding of the drug discovery process to guide program teams to define the key scientific questions, program strategy and objectives, translating these into optimal deliverables, cross-functional plans, timelines and budgets
• Identify bottlenecks, risks, issues and proactively develop appropriate mitigation proposals with input from team members
• Ensure all key decisions are identified and properly assessed as to their impact and alternative scenarios developed and evaluated, where appropriate
• Work closely with finance and functional teams to develop the operational plans to support program activities with realistic timelines, budget, and resource planning and monitor performance against plans
• Interface with and drive collaboration between the various functional teams and with the Leadership Team on program-related matters.
• Be the key accountable person for communicating matters related to the programs to management including strategy, work product, updates and issues; producing the one “source of truth” for program-related topics and timelines
• Point person for alliance management and coordination, as needed
• Lead and/or manage strategic or platform development projects as required and collaborate with Chief Scientific Officer and Research Leadership Team to coordinate relevant content for quarterly business review meetings

Operations:

• Collaborate with Leadership Team in development of strategic plans, company goals, long-range planning assumptions, portfolio-level reports and analyses to support business processes and strategic discussions
• Develop and deliver impactful presentations that effectively distill complex issues to the critical points and lead to increased understanding and optimized strategic planning & decision-making

• Prepare strategic communications utilizing a clear understanding of the business strategy and issues; develop and maintain consistent, relevant content for use in executive-level communications and to further organizational and business goals

• Lead the Scientific Communications process, working with the Scientific Communications Committee

• Manage schedule, agenda, and content for Leadership Team, Board of Directors and Town Hall meetings

• Proactively seek opportunities for organizational improvements (e.g. team structure, processes, communication, etc.)

Other:

• Support CEO / LT with partnership discussions and negotiations, including background research, preparation of presentation materials, supporting diligence activities, participating in analysis of terms, etc.
• Assist in mapping competitive landscape and proactively identify potential and emerging competitive threats and opportunities
• Promote strategic discussions on external trends, competitor strategies, and potential disruptors, and translate these into strategic choices/ recommendations
• Collect insights and intelligence from a variety of sources including literature searches, reviewing analyst research, KOL and patient group interactions, etc.

Key Competencies:

• This is a highly visible leadership role that requires exceptional interpersonal and communication skills, creative thinking, and early drug development experience that allows one to recognize opportunities/challenges and modify strategy accordingly
• The individual will need to have self-confidence and poise to manage complicated programs and projects with multiple stakeholders

• The individual will need a sense of urgency and can-do attitude to develop therapies for patients with significant unmet medical needs

Minimum Qualifications:

• BS/MS Degree in a scientific discipline, ideally life science or chemistry.
• At least 15 years relevant experience in pharma or biotech drug discovery and development, as well as a comprehensive understanding of drug discovery (preclinical and clinical).
• 10+ years of Program Management experience, preferably in early-stage drug discovery and development.
• Experience in the development of advanced therapies to treat rare genetic disease is a plus
• Demonstrated experience leading cross-functional teams; strong interpersonal and communication skills
• Scientific curiosity and passion for discovering new, innovative medicines.
• Openness to embrace new technologies and digital approaches in drug discovery
• Proven track record in driving successful, collaborative drug discovery teams.

The salary range for this role is $213,000 - $280,500. Compensation for the role will depend on a number of factors, including a candidate’s qualifications, skills, competencies, and experience. Alltrna currently offers healthcare coverage, annual incentive program, retirement benefits and a broad range of other benefits. Compensation and benefits information is based on Alltrna's good faith estimate as of the date of publication and may be modified in the future.

Director, Finance & Administration

Harvard Hillel

Location: On Site, Harvard Hillel  |  Cambridge, MA

Employment Status: Exempt salaried staff member

Reporting: Jason Rubenstein, Executive Director 

Salary Range: $100,000 - $120,000

Role Overview

The mission of Harvard Hillel is to be a Jewish home, both physical and virtual, on the Harvard University campus. Harvard Hillel welcomes all students to experience the variety of Jewish identity, tradition, practice, values, culture, and community and to inspire and enable connections on campus and beyond. Harvard Hillel students find meaningful connections and friendship while engaging in unique opportunities to make Jewish thought and culture integral in the life of the University.

The Director, Finance & Administration (Director) reports to the Harvard Hillel executive director who has been in the role less than two years. As a team, you will engage effectively with internal and external constituent groups around operational excellence at Harvard Hillel. The Director will move easily between strategic decision-making, governance requirements, and the everyday tactical coordination and planning that brings operational priorities to fruition. The Director serves as an empathetic and collaborative leader and coach, where operational excellence and a positive engagement around organizational culture is as important as rigorous monitoring of systems and process.

The Director’s role will ensure effective and consistent financial integrity and compliance of this 501(c)(3) institution. Working closely with the executive director, chief of staff, and other stakeholders, the Director will oversee the planning, coordination, and tracking of institutional annual goals against budget. The Director will serve as a trusted advisor and thought partner to the executive director and staff on organizational priorities, strategic goal setting, and effective project coordination in relation to designing and meeting budget goals.

Key to the success of the Director’s role is to add capacity to the executive director to support the transformation of the institution and its future. In year one, the Director will actively engage with colleagues and outsourced providers to modernize financial budgeting systems, tracking and reporting. Over time, a successful Director in this role will help reshape Harvard Hillel—its building and its operations, to move the organization forward.

Anticipated accountabilities are outlined below. The Director will be expected to actively surface and collaboratively projects to design and address anomalies to ensure work moves forward effectively and efficiently.

What You’ll Do

Annual Planning & Financial Management

• Accounting, Banking, Benefits, Insurances, Payroll: accountability for ensuring an annual cycle, with relevant systems, tracking, and reporting designed and implemented to record and reflect on the overall fiscal health of the organization.
  • Lead annual budget cycle: engaging with budget holders and other colleagues to establish and coordinate an effective budget planning process and reporting tools to support budget holders’ ability to manage and track their budgets and cashflow. At minimum, monthly and quarterly budget reviews, cash flow management and reporting, and ad-hoc tracking and issue resolution as needed. Ensure organizational priorities are visible, clear, and actionable in relation to budget monitoring and tracking. Lead communications in relation to annual budget cycle process and the obligations of contributors. Serve as a trusted colleague and coach around budget management, accountability, and tracking in relation to finance and budgets.
  • Lead annual cycle of audited financial statements and filings: engage with external providers to oversee and actively manage the timely scheduling and delivery of an annual audit; delivery of a 990, and to meet an annual schedule of filing obligations.
  • Annual Insurances: engage with a broker and others to manage insurance obligations for this 501(c)(3) organization.
  • Departmental planning and analyses: In year one, redesign financial planning, budgeting, tracking, and reporting systems, with analysis tools that are right-sized for the institution, in preparation for a capital project to renovate the historic Rosovsky building and to support the institution's journey to scale.

Board of Directors Operations

• Working closely with the chief of staff and executive director, and Board committees, plan and coordinate audit, finance, and risk related committees and reporting to meet timely Board reporting and meetings. Serve as the staff liaison for finance, audit, and risk related committee meetings and discussions.
• Support committee development, structures, and governance principles and processes to ensure the organization’s ByLaws support and drive compliance and governance decision-making in relation to financial risk.

Fiscal Sponsorships Management

• In close coordination with the Director of Programs and others, actively manage student-led initiatives related to financial controls, guidance on policy, procurement, and expenditures and timely payments of events for student-led projects.

Policy Design and Management

• Actively review and manage organizational policies in relation to both risk management and business continuity, balancing the organization’s values and core programming, to facilitate a smooth-running institution in service of students and other stakeholders.
• Schedule routine policy review cycles to ensure the organization is up to date with best practices and technologies to function with operational excellence.

Human Resources

• Work closely with payroll providers and benefits brokers to manage an annual benefits cycle of enrollments and benefits assessments, actively engaging and communicating with staff through a benefits review cycle.
• Actively engage with the chief of staff to design and implement an annual cycle of health and safety protocols specific to this institution. Working closely with the chief of staff and executive director, actively track and monitor engagement in mandatory trainings for Boston, MA.
• Work in close partnership as needed on staff disciplinary activities, including investigations, performance management support, hiring and termination, holding personnel records and record keeping for related human resources materials.

Facilities

• Oversee the planning of budgets and coordination support needs for buildings owned or rented by Harvard Hillel.
• Oversee the health and safety, security, and business continuity planning around onsite activities, in close partnership with the manager of facilities and operations and the executive director.
• Oversee onsite programmatic activities and events in close liaison with the Director of Program and Facilities Manager, ensuring smooth running of event scheduling, planning, and logistics.
• Oversee management and coordination of facilities technologies serve onsite programming through facilities.
• Identify and manage cost-savings opportunities for services provided by Harvard University and others.

Minimum Qualifications

• 10+ years of experience as a CFO with an Operations portfolio, Finance & Operations Manager, or similar role in a nonprofit or community engagement organization.
• High comfort in Microsoft Office tools, QBO, Bill.com, other financial management platforms.
• Bachelor’s Degree or equivalent.

Knowledge, Skills and Abilities 

• 8+ years of progressive experience in nonprofit or mission-driven leadership roles.
• Commitment to the organization’s mission and respectful of Jewish values.
• Demonstrated success in strategic planning and execution, operational systems and tracking, and Board governance. People-center systems thinker, with strong success operationalizing strategies into trackable, measurable action plans.
• Strong financial, project management, and institutional administration skills.
• Exceptional written, verbal, and interpersonal skills.
• Highly effective manager of people, projects, and budgets.
• Adaptable, sound judgment, diplomatic, and respectful of holding sensitive information.
• Ability to successfully balance high emotional intelligence with result-driven project management and serving as an empathetic culture carrier who models collaborative leadership and teamwork.
• Open and willing to engage in conversations about religion, and to learn about Judaism and Israel in a way that inspires stakeholders to invest in our work.
• Highly collaborative problem-solver with curiosity to engage across teams both inside and outside of Hillel to successfully manage competing priorities.
• A self-starter, adept at project management tools and practices, time-management and effective communications both verbally and in writing.
• Highly comfort working effectively both independently and in teams to meet goals and deadlines.

Benefits

• A comprehensive benefits package, including health insurance, retirement plan, Life, AD&D and Long-Term Disability (LTD) insurances, Flexible Spending accounts, generous vacation/sick time, and parental leave.
• A unique opportunity to develop and promote a vibrant, pluralistic Jewish community at Harvard Hillel.

Harvard Hillel is affiliated with Hillel International. Hillel International enriches the lives of Jewish students so they may enrich the Jewish people and the world, and envisions a world where every student is inspired to make an enduring commitment to Jewish life, learning and Israel.

Flagship Pioneering is a scientific innovation engine that invents and builds companies that change the world. We bring together the greatest scientific minds with entrepreneurial company builders and assemble the capital to allow them to take courageous leaps in human health, sustainability, and beyond. 

What sets Flagship apart is our ability to advance biotechnology by uniting life science innovation, company creation, and capital investment under one roof in a way that is largely without precedent. Our team of scientists, entrepreneurial leaders, and professional capital managers are each aligned around an institutionalized process that enables us to innovate and create breakthroughs for the benefit of people and planet.

Many of the companies Flagship has founded have addressed humanity’s most urgent challenges: vaccinating billions of people against COVID-19, curing intractable diseases, improving human health, preempting illness, and feeding the world by improving the resiliency and sustainability of agriculture.

Flagship has been recognized twice on FORTUNE’s “Change the World” list, an annual ranking of companies that have made a positive social and environmental impact through activities that are part of their core business strategies, and has been named four times to Fast Company’s annual list of the World’s Most Innovative Companies.

Position Overview

Flagship Pioneering is seeking an experienced and strategic Vice President or Senior Vice President, Total Rewards and People Operations to lead the design, management, and evolution of Total Rewards programs and key people infrastructure across our ecosystem. The scope of this role spans compensation, executive compensation, equity, benefits, people operations, and people analytics for Flagship and its portfolio of companies.

This is a highly visible leadership role requiring deep expertise in compensation strategy and private-company equity, as well as the ability to operate effectively across a complex, fast-paced, and highly matrixed environment. The ideal candidate will bring strong executive presence, sound judgment, and the ability to translate business strategy into scalable people programs that support growth, innovation, and organizational effectiveness.

This leader will oversee an established team across Compensation, Benefits, People Operations, and People Analytics, and will be expected to shape a modern, market-relevant Total Rewards philosophy, refine equity and incentive structures, advance benefits strategy, and drive people insights that support executive decision-making.

Key Responsibilities

Total Rewards Strategy and Leadership

• Lead the strategy, design, and ongoing evolution of Flagship’s global Total Rewards philosophy across compensation, executive compensation, equity, benefits, and other reward programs. 
• Serve as the principal architect of rewards strategy, recommending program direction to senior leadership and ensuring alignment with business priorities, talent strategy, and financial objectives. 
• Develop and refine salary structures, incentive frameworks, equity guidelines, and market positioning approaches across a global footprint. 
• Oversee job architecture and leveling governance in support of internal equity, talent management, and scalable compensation decision-making. 
• Guide annual compensation planning processes, including merit, bonus, promotion, and other pay actions, in partnership with HR, Finance, and business leadership. 
• Partner closely with Talent Acquisition and HR Business Partners on executive and broad-based offer strategy, market competitiveness, and internal equity. 
• Lead the continued evolution of executive compensation and broad-based equity strategy across Flagship and applicable portfolio companies. 

Equity and Incentive Design

• Provide strategic leadership for complex equity and long-term incentive programs, including private-company equity structures and alternative long-term incentive constructs. 
• Oversee equity strategy, governance, and operational execution through the team, ensuring strong program design and scalable administration. 
• Partner with senior leadership on the design and refinement of incentive and ownership frameworks that support attraction, retention, and long-term value creation. 
• Bring familiarity with innovative and non-traditional compensation approaches, including profits interests, carried interest, and related long-term incentive structures. 

Benefits Strategy

• Lead benefits strategy across health and welfare, retirement, leave, and ancillary programs, ensuring programs remain competitive, sustainable, and aligned with organizational values and workforce needs. 
• Partner with the Benefits leader and external advisors to evaluate plan design, funding, market trends, vendor performance, and evolving regulatory requirements. 
• Support harmonization and modernization of benefits strategy where appropriate across a diverse and growing ecosystem. 

People Operations

• Oversee key People Operations functions, including onboarding, offboarding, employee lifecycle processes, policy administration, compliance workflows, service delivery, and operational process excellence. 
• Ensure people processes are scalable, well-governed, and designed to support a high-quality employee and manager experience. 
• Partner effectively across HR, Payroll, IT, Legal, and Finance to improve operational efficiency and strengthen people-related infrastructure. 
• Provide leadership on HR compliance, as well as compensation- and benefits-related compliance considerations, in partnership with internal and external experts as appropriate. 

People Analytics

• Lead the People Analytics agenda, with an emphasis on generating insights that support executive decision-making across workforce planning, hiring, retention, compensation, and organizational effectiveness. 
• Oversee dashboards, reporting, and analytical frameworks that inform leaders including the CEO and CFO. 
• Translate data and analysis into actionable recommendations in partnership with HR Business Partners and business leaders. 
• Advance a thoughtful, increasingly sophisticated analytics capability that supports better people decisions across Flagship and the broader ecosystem. 

Portfolio Company Partnership

• Advise and support portfolio company leaders on Total Rewards strategy, with involvement calibrated to company stage, maturity, and business need. 
• Tailor rewards frameworks and guidance for a range of company stages while maintaining sound governance and alignment with broader talent and value creation goals. 
• Present recommendations and insights to portfolio company leadership and boards as needed. 

Leadership and Team Development

• Lead, develop, and inspire a multi-functional team spanning Compensation, Benefits, People Operations, and People Analytics. 
• Foster strong collaboration across functional teams and help continue building a high-performing, service-oriented, and strategically focused organization.
• Manage external consultants, brokers, survey providers, and other key vendors in support of rewards strategy and operational excellence. 

Qualifications

• 15+ years of progressive experience in Total Rewards, with significant depth in compensation strategy and experience leading broad, multi-functional teams. 
• Deep expertise in compensation design, market benchmarking, executive compensation, incentive strategy, and private-company equity. 
• Strong familiarity with alternative long-term incentive structures, including profits interests, carried interest, and other innovative ownership or reward constructs. 
• Experience leading or advising on benefits strategy, including health and welfare, retirement, leave, and ancillary offerings. 
• Experience overseeing or partnering closely with People Operations and People Analytics functions in complex organizations. 
• Demonstrated success operating in high-growth, founder-led, venture-backed, private equity, or similarly dynamic business environments. 
• Experience supporting global workforces and navigating matrixed organizations with multiple stakeholders and business models. 
• Strong executive presence with the ability to influence senior leaders, present compelling recommendations, and operate as a trusted advisor. 
• Proven ability to translate data and market insights into practical, business-relevant decisions and action plans. 
• Experience working with boards, founders, and senior executive stakeholders preferred. 
• Prior life sciences or biotechnology experience preferred, but not required. 

Why Join Flagship Pioneering?

This is a rare opportunity to play a critical role in shaping how a highly innovative organization rewards, supports, and scales exceptional talent. As Senior Vice President, Total Rewards and People Operations, you will operate at the intersection of business strategy, organizational design, and cutting-edge science, helping to build and evolve the people infrastructure that supports transformative work in human health and sustainability.

At Flagship, we recognize there is no perfect candidate. If you have some of the experience listed above but not all, please apply anyway. Experience comes in many forms, skills are transferable, and passion goes a long way. We are dedicated to building diverse and inclusive teams and look forward to learning more about your unique background.

Recruitment & Staffing Agencies: Flagship Pioneering and its affiliated Flagship Lab companies (collectively, “FSP”) do not accept unsolicited resumes from any source other than candidates. The submission of unsolicited resumes by recruitment or staffing agencies to FSP or its employees is strictly prohibited unless contacted directly by Flagship Pioneering’s internal Talent Acquisition team. Any resume submitted by an agency in the absence of a signed agreement will automatically become the property of FSP, and FSP will not owe any referral or other fees with respect thereto.

#LI-NM1

The salary range for this role is $300,000 - $400,000. Compensation for the role will depend on a number of factors, including a candidate’s qualifications, skills, competencies, and experience. Flagship Pioneering currently offers healthcare coverage, annual incentive program, retirement benefits and a broad range of other benefits. Compensation and benefits information is based on Flagship Pioneering's good faith estimate as of the date of publication and may be modified in the future.

Who We Are

Flagship Pioneering is a biotechnology company that invents and builds platform companies that change the world. We bring together the greatest scientific minds with entrepreneurial company builders and assemble capital to allow them to take courageous leaps. Those big leaps in human health and sustainability exponentially accelerate scientific progress in areas ranging from cancer detection and treatment to nature-positive agriculture.  

What sets Flagship apart is our ability to advance biotechnology by uniting life science innovation, company creation, and capital investment under one roof in a way that is largely without precedent. Our scientific founders, entrepreneurial leaders, and professional capital managers are each aligned around an institutionalized process that enables us to innovate and transform for the benefit of people and planet.  

Many of the companies Flagship has founded have addressed humanity’s most urgent challenges: vaccinating billions of people against COVID-19, curing intractable diseases, improving human health, preempting illness, and feeding the world by improving the resiliency and sustainability of agriculture. 

Flagship has been recognized twice on FORTUNE’s “Change the World” list, an annual ranking of companies that have made a positive social and environmental impact through activities that are part of their core business strategies and has been twice named to Fast Company’s annual list of the World’s Most Innovative Companies.

Position Summary:

The Director of Financial Reporting, Planning and Analysis (FP&A) is a core player in creating, growing, and building Flagship Pioneering early-stage companies. You will join the FP&A team in Flagship Labs Finance, primarily focusing on a set of NewCos or recent GrowthCos. You will be an instrumental player responsible for driving the annual planning cycle across the Flagship Lab companies, providing business insights to our leaders to measure progress on company performance and enhancing companywide financial reports, including enhanced analytics, finance modeling, cash flow management and consolidated reporting. This position provides an opportunity for professional growth and exposure to multiple Flagship-funded companies.

Key Responsibilities:

• Establish and maintain the financial models that inform and enable capital allocation in a dynamic business planning environment
• Work with Pioneering Business Units (PBU) leaders, their CFO/Heads of Finance, corporate teams, and the companies to develop and maintain the long-term value creation model 
• Partner with the PBU Controllers to support planning that is aligned with GL reporting structure and support functional and program costing 
• Responsible for all aspects of management reporting and analysis for operating and capital expenses, cash flow analysis and funding requirements for multiple business scenarios
• Partner with HR to reliably track and report actual and projected headcount, including open reqs and progress against hiring plans and budgets
• Provide analytical support and modeling for business development deals
• Provide financial analysis to support critical portfolio and business decisions such as evaluation of indication selection, commercial opportunity analysis, make vs buy, etc. 
• Compile relevant financial information and presentations for internal (BOD, management) and external (lender, investors, partners) stakeholders, including meaningful data visualization as needed

Qualifications:

• 10+ years’ experience in FP&A roles in the biotech/pharmaceutical industry, preferably a high growth environment. Candidates with experience in MedTech and AgTech will be considered
• Experience with public companies preferred.  A combination with small private/start-up experience will be an advantage to thrive in a fast-growing and rapidly changing environment, comfortable with ambiguity
• Expertise building relationships with various stakeholders and working with senior leaders
• Direct experience with data manipulation and visualization tools is a plus (e.g., Power BI)
• Master’s degree in accounting or finance. MBA or CPA is a plus

Flagship Pioneering and our ecosystem companies are committed to equal employment opportunity regardless of race, color, ancestry, religion, sex, national origin, sexual orientation, age, citizenship, marital status, disability, gender identity or Veteran status.

At Flagship, we recognize there is no perfect candidate. If you have some of the experience listed above but not all, please apply anyway. Experience comes in many forms, skills are transferable, and passion goes a long way. We are dedicated to building diverse and inclusive teams and look forward to learning more about your unique background.

Recruitment & Staffing Agencies: Flagship Pioneering and its affiliated Flagship Lab companies (collectively, “FSP”) do not accept unsolicited resumes from any source other than candidates. The submission of unsolicited resumes by recruitment or staffing agencies to FSP or its employees is strictly prohibited unless contacted directly by Flagship Pioneering’s internal Talent Acquisition team. Any resume submitted by an agency in the absence of a signed agreement will automatically become the property of FSP, and FSP will not owe any referral or other fees with respect thereto.

#LI-NM1

The salary range for this role is $172,000 - $236,500. Compensation for the role will depend on a number of factors, including a candidate’s qualifications, skills, competencies, and experience. Flagship Pioneering currently offers healthcare coverage, annual incentive program, retirement benefits and a broad range of other benefits. Compensation and benefits information is based on Flagship Pioneering's good faith estimate as of the date of publication and may be modified in the future.

Quotient is seeking a hands-on, highly experienced Vice President of Finance who has experience working in a private biotech company with both pre-clinical and clinical programs. The ideal candidate will have strong finance expertise, experience with technical and operational accounting, proven experience as a leader, and a demonstrated ability to build innovative finance teams and systems. This individual must be comfortable working independently in a resource-constrained environment while building out the finance function and also providing strategic financial guidance to the executive team.

The Vice President of Finance will be responsible for overseeing all aspects of accounting, financial operations, and compliance while contributing meaningfully to corporate strategy and long-term planning. This is a key leadership role within the company and is the primary steward of financial strategy, discipline, systems, and governance.

Responsibilities: 

• Initially serve as the company’s controller, overseeing all accounting operations, financial reporting, and internal controls; ensure compliance with GAAP and all applicable regulations, manage monthly, quarterly and annual close processes as well as tax and regulatory filings, and initiate/lead financial statement audits
• Partner with the CFO and leadership team to develop and refine the company’s financial strategy and long term operating plan; provide scenario modeling, budgets, forecasts, long range planning models and capital allocation recommendations, and support fundraising activities, investor relations and board-level financial reporting
• Implement and maintain innovative and scalable accounting and financial systems, processes and tools; oversee cash flow management, including tracking of R&D expenses, collaboration budgets and operational spend, and lead implementation of accounting and finance systems independent from the Flagship ecosystem
• Plan and build out a small internal finance team, fostering growth and accountability; develop and oversee launch of finance function independent of Flagship support, oversee and coordinate work of external vendors, including auditors, accounting consultants, tax advisors and payroll providers, ensuring vendors meet performance expectations, budgets and timelines

Qualifications:

Essential

• 15+ years of progressive finance and accounting experience, including senior leadership roles 
• Proven track record in a private life sciences/biotech company with both clinical and pre-clinical programs
• Strong understanding of GAAP and biotech-specific accounting issues, including R&D accruals and clinical trial accounting
• Experience leading budgeting, financial reporting and long range planning processes
• Experience building teams and system transitions/implementations
• Experience managing direct reports and external vendors
• Demonstrated ability to work independently in a fast-paced, entrepreneurial environment

Desirable

• CPA or MBA strongly preferred 
• Experience supporting fundraising activities (venture capital, crossover, IPO readiness)
• Understanding of and interest in utilizing AI and automation for finance 
• Familiarity with biopharma collaboration accounting and reporting as well as cost modeling for clinical development and pre-clinical programs

Values and Behaviors:

• Encourage respectful disagreement and cultivate open-minded, ego-free interactions to continuously push each other towards excellence
• Seek out diverse perspectives; practice active listening and genuine curiosity to ensure all contributions are valued, regardless of source
• Recognize the impact of your behavior, language and attitudes, and strive for balanced, meaningful exchanges that enhance mutual growth and understanding in all interactions
• Use a company-first mindset to guide decision-making; prioritize team over individual success
• Take calculated risks and challenge convention in the quest for exceptional outcomes

About Quotient:

Quotient Therapeutics is a privately-held, early stage company developing breakthrough medicines informed by natural somatic genetic diversity present in patients. Through our work in somatic genomics, we are forging a new status quo for biopharma research and development across a broad pipeline of internal and partnered programs.  

The company was founded by Flagship Pioneering, an innovative enterprise that conceives, creates, resources, and grows first-in-category life sciences companies. Flagship Pioneering has created over 100 groundbreaking companies over the past twenty years, all of which are pioneering novel and proprietary biological, industrial, and engineering approaches to solve major needs in human health and sustainability. These companies include Moderna (MRNA), Generate Biomedicines, Sana Biotechnology (SANA), Tessera Therapeutics, Evelo Biosciences (EVLO), Indigo Agriculture, Seres Therapeutics (MCRB), and Syros Pharmaceuticals (SYRS).

Quotient Therapeutics and Flagship Pioneering are committed to equal employment opportunity regardless of race, color, ancestry, religion, sex, national origin, sexual orientation, age, citizenship, marital status, disability, gender identity or Veteran status.

Recruitment & Staffing Agencies:

Quotient Therapeutics (“Quotient”) and Flagship Pioneering (“FSP”) do not accept unsolicited resumes from any source other than candidates. The submission of unsolicited resumes by recruitment or staffing agencies to Quotient, FSP or their employees is strictly prohibited unless contacted directly by Flagship Pioneering’s internal Talent Acquisition team. Any resume submitted by an agency in the absence of a signed agreement will automatically become the property of FSP, and FSP will not owe any referral or other fees with respect thereto.

The salary range for this role is $250,000 - $350,000. Compensation for the role will depend on a number of factors, including a candidate’s qualifications, skills, competencies, and experience. Quotient Therapeutics, Inc. currently offers healthcare coverage, annual incentive program, retirement benefits and a broad range of other benefits. Compensation and benefits information is based on Quotient Therapeutics, Inc.'s good faith estimate as of the date of publication and may be modified in the future.