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Senior Machine Learning Scientist
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Join Axon and be a Force for Good.
At Axon, we’re on a mission to Protect Life. We’re explorers, pursuing society’s most critical safety and justice issues with our ecosystem of devices and cloud software. Like our products, we work better together. We connect with candor and care, seeking out diverse perspectives from our customers, communities and each other.
Life at Axon is fast-paced, challenging and meaningful. Here, you’ll take ownership and drive real change. Constantly grow as you work hard for a mission that matters at a company where you matter.
Your Impact
We are seeking highly skilled and innovative Machine Learning Scientists to join our AI team, focusing on AI applications (LLM and Computer Vision) in Cloud, Devices and Robotics. As a key member of our research and development efforts, you will play a crucial role in advancing the state-of-the-art in Large Language Models (LLMs), Multimodal Large Language Models (MLLMs), Computer Vision and GenAI technologies for law enforcement and beyond. You will collaborate with cross-functional teams to design, develop, and deploy cutting-edge LLM, MLLM, CV models and algorithms and solutions that enable intelligent reasoning, perception and understanding of multimodal data.
What You’ll Do
Location: any cities with Axon Engineering Hub in US, Vietnam, EU (see https://www.axon.com/company)
- US: Seattle, Boston, Scottsdale
Responsibilities
- Own one or more key technical areas across LLM, MLLM, CV product portfolio.
- Provide technical leadership to junior scientists, guiding the transition of R&D concepts into impactful Axon product feature.
- Research and develop cutting-edge techniques in LLM, MLLMs, GenAI, and Computer Vision across cloud, devices and sensors based data sources.
- Design and implement efficient and scalable MLLM models for inference and analysis of multimodal data.
- Explore novel approaches to address challenges in NLP, NLU, Object Detection, Object Recognition, Object Tracking, Segmentation, and Scene Understanding.
- Optimize AI models, algorithms for performance, memory footprint, and energy efficiency to meet the requirements of resource-constrained devices.
- Join force with MLEs or firmware or hardware engineers to leverage hardware accelerators and optimize algorithms for specific hardware architectures.
- Evaluate the performance of LLM, MLLM, CV models using real-world datasets and design experiments to validate their effectiveness.
- Stay up-to-date with the latest research trends and advancements in computer vision, machine learning, and deep learning, MLLMs, GenAI and integrate relevant findings into our projects.
- Contribute to patent disclosures, academic publications, and technical documentation to share insights and findings with the broader community.
- Experience coach and mentor junior scientists.
What You Bring
- PhD and with +5 years for ML Scientist, +8 years for Sr. ML Scientist, +10 years for Principal ML Scientist experience in Computer Science or a related field with a focus on LLM, MLLMs, Computer Vision, GenAI.
- Proven track record of research excellence in LLM, MLLM, Computer Vision, Robotics Perception, GenAI, demonstrated through publications in top-tier conferences or journals.
- Strong proficiency in programming languages such as Python, C/C++, experience with deep learning frameworks such as TensorFlow, PyTorch, or Keras and experience with ROS or robotic operational system.
- Drive one or more phases of the ML development lifecycle: shape datasets, investigate modeling approaches and architectures, train/evaluate/tune models and implement the end-to-end training pipeline.
- Leverage state-of-the-art research to deliver high quality models enabling multiple AI projects at scale.
- Contribute back to the research community via academic publications, tech blogs, open-source code and contributing to internal/external AI challenges
- Experience in developing computer vision algorithms for resource-constrained devices such as mobile phones, IoT devices, or embedded systems is highly desirable.
- Excellent problem-solving skills, analytical thinking, and the ability to work independently as well as collaboratively in a team environment.
- Strong communication skills and the ability to effectively present complex technical concepts to both technical and non-technical audiences.
Benefits that Benefit You
- Competitive salary and 401k with employer match
- Discretionary paid time off
- Paid parental leave for all
- Medical, Dental, Vision plans
- Fitness Programs
- Emotional & Mental Wellness support
- Learning & Development programs
- And yes, we have snacks in our offices
Benefits listed herein may vary depending on the nature of your employment and the location where you work
Location: This role is based out of our Boston, MA office and follows a hybrid schedule. We rely on in-person collaboration and ask that team members work onsite Tuesday through Friday, with flexibility to work remotely on Mondays. We believe connection fuels innovation, and our in-office culture is designed to support meaningful teamwork and mentorship.
Axon is a total compensation company, meaning compensation is made up of base pay, bonus, and stock awards. The actual base pay is dependent upon many factors, such as: level, function, training, transferable skills, work experience, business needs, geographic market, and often a combination of all these factors. Our benefits offer an array of options to help support you physically, financially and emotionally through the big milestones and in your everyday life. To see more details on our benefits offerings please visit https://www.axon.com/careers.
Don’t meet every single requirement? That's ok. At Axon, we Aim Far. We think big with a long-term view because we want to reinvent the world to be a safer, better place. We are also committed to building diverse teams that reflect the communities we serve.
Studies have shown that women and people of color are less likely to apply to jobs unless they check every box in the job description. If you’re excited about this role and our mission to Protect Life but your experience doesn’t align perfectly with every qualification listed here, we encourage you to apply anyways. You may be just the right candidate for this or other roles.
Important Notes
The above job description is not intended as, nor should it be construed as, exhaustive of all duties, responsibilities, skills, efforts, or working conditions associated with this job. The job description may change or be supplemented at any time in accordance with business needs and conditions.
Some roles may also require legal eligibility to work in a firearms environment.
We collect personal information from applicants to evaluate candidates for employment. You may request access, deletion, or exercise other CCPA rights at axongreenhousesupport@axon.com or via our Axon Privacy Web Form. For more information, please see the Your California Privacy Rights section of our Applicant and Candidate Privacy Notice.
Axon’s mission is to Protect Life and is committed to the well-being and safety of its employees as well as Axon’s impact on the environment. All Axon employees must be aware of and committed to the appropriate environmental, health, and safety regulations, policies, and procedures. Axon employees are empowered to report safety concerns as they arise and activities potentially impacting the environment.
We are an equal opportunity employer that promotes justice, advances equity, values diversity and fosters inclusion. We’re committed to hiring the best talent — regardless of race, creed, color, ancestry, religion, sex (including pregnancy), national origin, sexual orientation, age, citizenship status, marital status, disability, gender identity, genetic information, veteran status, or any other characteristic protected by applicable laws, regulations and ordinances — and empowering all of our employees so they can do their best work. If you have a disability or special need that requires assistance or accommodation during the application or the recruiting process, please email recruitingops@axon.com. Please note that this email address is for accommodation purposes only. Axon will not respond to inquiries for other purposes.
Phishing alert: Axon will never ask you to pay for any part of the hiring process, including training, equipment, or background checks. We do not make job offers via text message, WhatsApp, or instant messaging platforms without a formal interview process. All legitimate job openings are listed on our official careers page at https://www.axon.com/careers. If you receive a suspicious offer or outreach from an email address that is not @axon.com, or if you are asked for sensitive personal information (bank details, Social Security Number) prematurely, please ignore the message and report it to recruitingops@axon.com.
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Apply to AxonSenior Scientist, Computational Protein Design
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About Abiologics
Abiologics is a Flagship Pioneering company developing Synteins™ — a transformative class of fully synthetic proteins composed entirely of artificial building blocks such as D-amino acids and non-canonical residues. SynteinsTM are designed to transcend the limitations of traditional biologics, with improved oral stability, immune evasion, and metabolic durability — all while being fully programmable by design.
Powered by a proprietary AI-enabled discovery platform, Abiologics integrates generative design, automated synthesis, and rapid experimental screening to enable iterative optimization at scale.
Position Summary
We are seeking a Protein Design Scientist to join the Computational Protein Design team and help drive structure-based design and optimization of synthetic proteins. This is a highly interdisciplinary role at the interface of computational design, structural biology, and protein engineering.
Ideal candidates have deep experience in de novo protein design, miniproteins, and binders engineering and are eager to push the boundaries of non-natural protein design in a fast-moving, data-rich environment.
Key Responsibilities
- Design and execute SynteinsTM engineering campaigns to generate drug candidates.
- Create computational design strategies to deliver drug candidates drawing from array of ML tools and Rosetta scripts.
- Collaborate with computation, chemistry, and experimental biology teams to optimize designs for function, solubility, and stability.
- Integrate structural and biophysical data (e.g., binding, CD, HDX-MS, CryoEM) into iterative optimization cycles
Qualifications
Required
- PhD in structural biology, biophysics, protein design, or related field
- 2+ years of hands-on experience in structure-guided protein design
- Demonstrated proficiency with modern structure prediction and design tools such as RFdiffusion, proteinMPNN, AF2, Boltz2, BoltzGen, Rosetta or equivalent SOTA tools for in-silico protein engineering.
- Strong understanding of the biophysics of protein folding and interface energetics
- Demonstrated ability to progress designs from concept to experimental testing
- Excellent communication skills
Preferred
- Experience designing minibinders or proteins <100 AAs
- Familiarity with non-canonical amino acid design
- Familiarity with molecular dynamics tools.
- Exposure to high-throughput or automated protein engineering environments
- Prior work on platform-based or early-stage biotech teams
Why Join Abiologics
- Help invent a new class of programmable synthetic proteins
- Be part of a high-velocity discovery platform with real-time synthesis and screening
- Collaborate with a deeply interdisciplinary, mission-driven team
- Redefine the limits of what proteins can do
ABOUT FLAGSHIP PIONEERING:
Flagship Pioneering invents and builds platform companies, each with the potential for multiple products that transform human health, sustainability and beyond. Since its launch in 2000, Flagship has originated more than 100 companies. Many of these companies have addressed humanity’s most urgent challenges: vaccinating billions of people against COVID-19, curing intractable diseases, improving human health, preempting illness, and feeding the world by improving the resiliency and sustainability of agriculture.
Flagship has been recognized twice on FORTUNE’s “Change the World” list, an annual ranking of companies that have made a positive social and environmental impact through activities that are part of their core business strategies and has been twice named to Fast Company’s annual list of the World’s Most Innovative Companies. Learn more about Flagship at www.flagshippioneering.com.
At Flagship, we accept impossible missions to enable bigger leaps. Our core values guide us through uncertainty and toward lasting impact.
We are an equal opportunity employer. All qualified applicants will be considered for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, disability, protected veteran status, or any other characteristic protected by law.
We recognize that great candidates often bring unique strengths without fulfilling every qualification. If you have some of the experience listed above but not all, please apply anyway. We are dedicated to building diverse and inclusive teams and look forward to learning more about your background and interest in Flagship.
Recruitment & Staffing Agencies: Flagship Pioneering and its affiliated Flagship Lab companies (collectively, “FSP”) do not accept unsolicited resumes from any source other than candidates. The submission of unsolicited resumes by recruitment or staffing agencies to FSP or its employees is strictly prohibited unless contacted directly by Flagship Pioneering’s internal Talent Acquisition team. Any resume submitted by an agency in the absence of a signed agreement will automatically become the property of FSP, and FSP will not owe any referral or other fees with respect thereto.
#LI-MB1
The salary range for this role is $146,000 - $209,000. Compensation for the role will depend on a number of factors, including a candidate’s qualifications, skills, competencies, and experience. Abiologics, Inc currently offers healthcare coverage, annual incentive program, retirement benefits and a broad range of other benefits. Compensation and benefits information is based on Abiologics, Inc's good faith estimate as of the date of publication and may be modified in the future.
Privacy Notice for Applicants: When you apply for a role at Abiologics, a Flagship Pioneering portfolio company, we collect and use personal information you provide (such as your name, contact details, work history, and application materials) to evaluate your application, communicate with you, and comply with legal obligations. Your application data is processed through Greenhouse, our applicant tracking system, and may also be reviewed using AI-assisted screening tools. We do not sell your personal information. California residents have rights under the CCPA/CPRA including to know, delete, and opt out of the sharing of their personal information. If you are located in the EU or UK, we process your data under GDPR and you have rights to access, rectify, and erase your data. To exercise your rights or for questions, contact privacy@flagshippioneering.com.
Ready to apply?
Apply to AbiologicsSenior Scientist, Medicinal Chemistry
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COMPANY DESCRIPTION
Abiologics, Inc. is a privately held, early-stage biotechnology company on a mission to make biology better through an innovative therapeutic modality. We are pioneering the development of Synteins™, a transformational class of macromolecular medicines unlocked by novel synthetic and computational technologies. Abiologics is actively seeking exceptional scientists who are passionate about driving therapeutic modality innovation in biotechnology.
Abiologics was founded in Flagship Pioneering’s venture creation engine, where companies such as Moderna Therapeutics (NASDAQ: MRNA) and Generate Biomedicines were conceived and created. Since Flagship’s founding in 2000, the firm has originated and fostered the development of more than 100 scientific ventures resulting in more than 500 issued patents and more than 50 clinical trials for novel therapeutic agents.
THE ROLE
We are seeking an experienced and motivated Senior Scientist in Medicinal Chemistry specializing in miniprotein and peptide drugs. The successful candidate will lead projects in designing, synthesizing, and optimizing novel miniprotein therapeutics called Synteins™. This role offers a unique opportunity to bring a new drug modality from early-stage research through to clinical development.
KEY RESPONSIBILITIES
- Independently plan, execute, interpret, and optimize Syntein structure-activity campaigns through direct, hands-on laboratory work.
- Implement modern peptide chemistry and conjugation methodologies to accelerate optimization of miniprotein drug development.
- Collaborate with cross-functional teams including computational chemistry, biology, and pharmacology to drive project success.
- Drive bench-side innovation, ensuring that ideas transition seamlessly from concept to reality
- Mentor and guide junior scientists, fostering a collaborative and dynamic laboratory environment.
- Contribute to patent applications and scientific publications, showcasing lab innovation.
PROFESSIONAL EXPERIENCE & QUALIFICATIONS
- Ph.D. (with a minimum of 5 years of industry experience) or M.S. (with a minimum of 12 years of industry experience) in Medicinal Chemistry, Synthetic Organic Chemistry, Chemical Biology, or related field
- Strong track record of laboratory-based innovation and problem-solving in drug discovery including optimization of affinity, selectivity, drug properties, and PK profile.
- Proven expertise in the hands-on peptide synthesis.
- Ability to lead and inspire a team of scientists in a dynamic research setting.
- Excellent communication skills for both technical and non-technical audiences.
- Able to work on-site and attend in-person meetings.
ABOUT FLAGSHIP PIONEERING:
Flagship Pioneering invents and builds platform companies, each with the potential for multiple products that transform human health, sustainability and beyond. Since its launch in 2000, Flagship has originated more than 100 companies. Many of these companies have addressed humanity’s most urgent challenges: vaccinating billions of people against COVID-19, curing intractable diseases, improving human health, preempting illness, and feeding the world by improving the resiliency and sustainability of agriculture.
Flagship has been recognized twice on FORTUNE’s “Change the World” list, an annual ranking of companies that have made a positive social and environmental impact through activities that are part of their core business strategies and has been twice named to Fast Company’s annual list of the World’s Most Innovative Companies. Learn more about Flagship at www.flagshippioneering.com.
At Flagship, we accept impossible missions to enable bigger leaps. Our core values guide us through uncertainty and toward lasting impact.
We are an equal opportunity employer. All qualified applicants will be considered for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, disability, protected veteran status, or any other characteristic protected by law.
We recognize that great candidates often bring unique strengths without fulfilling every qualification. If you have some of the experience listed above but not all, please apply anyway. We are dedicated to building diverse and inclusive teams and look forward to learning more about your background and interest in Flagship.
Recruitment & Staffing Agencies: Flagship Pioneering and its affiliated Flagship Lab companies (collectively, “FSP”) do not accept unsolicited resumes from any source other than candidates. The submission of unsolicited resumes by recruitment or staffing agencies to FSP or its employees is strictly prohibited unless contacted directly by Flagship Pioneering’s internal Talent Acquisition team. Any resume submitted by an agency in the absence of a signed agreement will automatically become the property of FSP, and FSP will not owe any referral or other fees with respect thereto.
#LI-MB1
The salary range for this role is $126,000 - $181,500. Compensation for the role will depend on a number of factors, including a candidate’s qualifications, skills, competencies, and experience. Abiologics, Inc currently offers healthcare coverage, annual incentive program, retirement benefits and a broad range of other benefits. Compensation and benefits information is based on Abiologics, Inc’s good faith estimate as of the date of publication and may be modified in the future.
Privacy Notice for Applicants: When you apply for a role at Abiologics, a Flagship Pioneering portfolio company, we collect and use personal information you provide (such as your name, contact details, work history, and application materials) to evaluate your application, communicate with you, and comply with legal obligations. Your application data is processed through Greenhouse, our applicant tracking system, and may also be reviewed using AI-assisted screening tools. We do not sell your personal information. California residents have rights under the CCPA/CPRA including to know, delete, and opt out of the sharing of their personal information. If you are located in the EU or UK, we process your data under GDPR and you have rights to access, rectify, and erase your data. To exercise your rights or for questions, contact privacy@flagshippioneering.com.
Ready to apply?
Apply to Abiologics
Senior Scientist, Computational Protein Design
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About Abiologics
Abiologics is a Flagship Pioneering company developing Synteins™ — a transformative class of fully synthetic proteins composed entirely of artificial building blocks such as D-amino acids and non-canonical residues. SynteinsTM are designed to transcend the limitations of traditional biologics, with improved oral stability, immune evasion, and metabolic durability — all while being fully programmable by design.
Powered by a proprietary AI-enabled discovery platform, Abiologics integrates generative design, automated synthesis, and rapid experimental screening to enable iterative optimization at scale.
Position Summary
We are seeking a Protein Design Scientist to join the Computational Protein Design team and help drive structure-based design and optimization of synthetic proteins. This is a highly interdisciplinary role at the interface of computational design, structural biology, and protein engineering.
Ideal candidates have deep experience in de novo protein design, miniproteins, and binders engineering and are eager to push the boundaries of non-natural protein design in a fast-moving, data-rich environment.
Key Responsibilities
- Design and execute SynteinsTM engineering campaigns to generate drug candidates.
- Create computational design strategies to deliver drug candidates drawing from array of ML tools and Rosetta scripts.
- Collaborate with computation, chemistry, and experimental biology teams to optimize designs for function, solubility, and stability.
- Integrate structural and biophysical data (e.g., binding, CD, HDX-MS, CryoEM) into iterative optimization cycles
Qualifications
Required
- PhD in structural biology, biophysics, protein design, or related field
- 2+ years of hands-on experience in structure-guided protein design
- Demonstrated proficiency with modern structure prediction and design tools such as RFdiffusion, proteinMPNN, AF2, Boltz2, BoltzGen, Rosetta or equivalent SOTA tools for in-silico protein engineering.
- Strong understanding of the biophysics of protein folding and interface energetics
- Demonstrated ability to progress designs from concept to experimental testing
- Excellent communication skills
Preferred
- Experience designing minibinders or proteins <100 AAs
- Familiarity with non-canonical amino acid design
- Familiarity with molecular dynamics tools.
- Exposure to high-throughput or automated protein engineering environments
- Prior work on platform-based or early-stage biotech teams
Why Join Abiologics
- Help invent a new class of programmable synthetic proteins
- Be part of a high-velocity discovery platform with real-time synthesis and screening
- Collaborate with a deeply interdisciplinary, mission-driven team
- Redefine the limits of what proteins can do
ABOUT FLAGSHIP PIONEERING:
Flagship Pioneering invents and builds platform companies, each with the potential for multiple products that transform human health, sustainability and beyond. Since its launch in 2000, Flagship has originated more than 100 companies. Many of these companies have addressed humanity’s most urgent challenges: vaccinating billions of people against COVID-19, curing intractable diseases, improving human health, preempting illness, and feeding the world by improving the resiliency and sustainability of agriculture.
Flagship has been recognized twice on FORTUNE’s “Change the World” list, an annual ranking of companies that have made a positive social and environmental impact through activities that are part of their core business strategies and has been twice named to Fast Company’s annual list of the World’s Most Innovative Companies. Learn more about Flagship at www.flagshippioneering.com.
At Flagship, we accept impossible missions to enable bigger leaps. Our core values guide us through uncertainty and toward lasting impact.
We are an equal opportunity employer. All qualified applicants will be considered for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, disability, protected veteran status, or any other characteristic protected by law.
We recognize that great candidates often bring unique strengths without fulfilling every qualification. If you have some of the experience listed above but not all, please apply anyway. We are dedicated to building diverse and inclusive teams and look forward to learning more about your background and interest in Flagship.
Recruitment & Staffing Agencies: Flagship Pioneering and its affiliated Flagship Lab companies (collectively, “FSP”) do not accept unsolicited resumes from any source other than candidates. The submission of unsolicited resumes by recruitment or staffing agencies to FSP or its employees is strictly prohibited unless contacted directly by Flagship Pioneering’s internal Talent Acquisition team. Any resume submitted by an agency in the absence of a signed agreement will automatically become the property of FSP, and FSP will not owe any referral or other fees with respect thereto.
#LI-MB1
The salary range for this role is $146,000 - $209,000. Compensation for the role will depend on a number of factors, including a candidate’s qualifications, skills, competencies, and experience. Abiologics, Inc currently offers healthcare coverage, annual incentive program, retirement benefits and a broad range of other benefits. Compensation and benefits information is based on Abiologics, Inc's good faith estimate as of the date of publication and may be modified in the future.
Privacy Notice for Applicants: When you apply for a role at Flagship Pioneering or one of its portfolio companies, we collect and use personal information you provide (such as your name, contact details, work history, and application materials) to evaluate your application, communicate with you, and comply with legal obligations. Your application data is processed through Greenhouse, our applicant tracking system, and may also be reviewed using AI-assisted screening tools. We do not sell your personal information. California residents have rights under the CCPA/CPRA including to know, delete, and opt out of the sharing of their personal information. If you are located in the EU or UK, we process your data under GDPR and you have rights to access, rectify, and erase your data. To exercise your rights or for questions, contact privacy@flagshippioneering.com.
Ready to apply?
Apply to Flagship Pioneering, Inc.
Senior Scientist, Medicinal Chemistry
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COMPANY DESCRIPTION
Abiologics, Inc. is a privately held, early-stage biotechnology company on a mission to make biology better through an innovative therapeutic modality. We are pioneering the development of Synteins™, a transformational class of macromolecular medicines unlocked by novel synthetic and computational technologies. Abiologics is actively seeking exceptional scientists who are passionate about driving therapeutic modality innovation in biotechnology.
Abiologics was founded in Flagship Pioneering’s venture creation engine, where companies such as Moderna Therapeutics (NASDAQ: MRNA) and Generate Biomedicines were conceived and created. Since Flagship’s founding in 2000, the firm has originated and fostered the development of more than 100 scientific ventures resulting in more than 500 issued patents and more than 50 clinical trials for novel therapeutic agents.
THE ROLE
We are seeking an experienced and motivated Senior Scientist in Medicinal Chemistry specializing in miniprotein and peptide drugs. The successful candidate will lead projects in designing, synthesizing, and optimizing novel miniprotein therapeutics called Synteins™. This role offers a unique opportunity to bring a new drug modality from early-stage research through to clinical development.
KEY RESPONSIBILITIES
- Independently plan, execute, interpret, and optimize Syntein structure-activity campaigns through direct, hands-on laboratory work.
- Implement modern peptide chemistry and conjugation methodologies to accelerate optimization of miniprotein drug development.
- Collaborate with cross-functional teams including computational chemistry, biology, and pharmacology to drive project success.
- Drive bench-side innovation, ensuring that ideas transition seamlessly from concept to reality
- Mentor and guide junior scientists, fostering a collaborative and dynamic laboratory environment.
- Contribute to patent applications and scientific publications, showcasing lab innovation.
PROFESSIONAL EXPERIENCE & QUALIFICATIONS
- Ph.D. (with a minimum of 5 years of industry experience) or M.S. (with a minimum of 12 years of industry experience) in Medicinal Chemistry, Synthetic Organic Chemistry, Chemical Biology, or related field
- Strong track record of laboratory-based innovation and problem-solving in drug discovery including optimization of affinity, selectivity, drug properties, and PK profile.
- Proven expertise in the hands-on peptide synthesis.
- Ability to lead and inspire a team of scientists in a dynamic research setting.
- Excellent communication skills for both technical and non-technical audiences.
- Able to work on-site and attend in-person meetings.
ABOUT FLAGSHIP PIONEERING:
Flagship Pioneering invents and builds platform companies, each with the potential for multiple products that transform human health, sustainability and beyond. Since its launch in 2000, Flagship has originated more than 100 companies. Many of these companies have addressed humanity’s most urgent challenges: vaccinating billions of people against COVID-19, curing intractable diseases, improving human health, preempting illness, and feeding the world by improving the resiliency and sustainability of agriculture.
Flagship has been recognized twice on FORTUNE’s “Change the World” list, an annual ranking of companies that have made a positive social and environmental impact through activities that are part of their core business strategies and has been twice named to Fast Company’s annual list of the World’s Most Innovative Companies. Learn more about Flagship at www.flagshippioneering.com.
At Flagship, we accept impossible missions to enable bigger leaps. Our core values guide us through uncertainty and toward lasting impact.
We are an equal opportunity employer. All qualified applicants will be considered for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, disability, protected veteran status, or any other characteristic protected by law.
We recognize that great candidates often bring unique strengths without fulfilling every qualification. If you have some of the experience listed above but not all, please apply anyway. We are dedicated to building diverse and inclusive teams and look forward to learning more about your background and interest in Flagship.
Recruitment & Staffing Agencies: Flagship Pioneering and its affiliated Flagship Lab companies (collectively, “FSP”) do not accept unsolicited resumes from any source other than candidates. The submission of unsolicited resumes by recruitment or staffing agencies to FSP or its employees is strictly prohibited unless contacted directly by Flagship Pioneering’s internal Talent Acquisition team. Any resume submitted by an agency in the absence of a signed agreement will automatically become the property of FSP, and FSP will not owe any referral or other fees with respect thereto.
#LI-MB1
The salary range for this role is $126,000 - $181,500. Compensation for the role will depend on a number of factors, including a candidate’s qualifications, skills, competencies, and experience. Abiologics, Inc currently offers healthcare coverage, annual incentive program, retirement benefits and a broad range of other benefits. Compensation and benefits information is based on Abiologics, Inc’s good faith estimate as of the date of publication and may be modified in the future.
Privacy Notice for Applicants: When you apply for a role at Flagship Pioneering or one of its portfolio companies, we collect and use personal information you provide (such as your name, contact details, work history, and application materials) to evaluate your application, communicate with you, and comply with legal obligations. Your application data is processed through Greenhouse, our applicant tracking system, and may also be reviewed using AI-assisted screening tools. We do not sell your personal information. California residents have rights under the CCPA/CPRA including to know, delete, and opt out of the sharing of their personal information. If you are located in the EU or UK, we process your data under GDPR and you have rights to access, rectify, and erase your data. To exercise your rights or for questions, contact privacy@flagshippioneering.com.
Ready to apply?
Apply to Flagship Pioneering, Inc.
(Senior) Scientist, ML/AI Antibody Design
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Company Summary:
FL106 Inc., is a privately held, early-stage biotechnology company focused on developing novel drug delivery modalities. FL106 is backed by Flagship Pioneering, bringing the vision and resources to guide FL106 from platform validation to real-world solutions that meaningfully improve patient care.
Position Summary:
We are seeking a passionate, creative, and self-driven (senior) scientist with expertise in computational protein design and state of the art AI/ML tooling for antibody and protein design to join our team. This candidate will pioneer the design of novel protein-based delivery modalities and collaborate with the experimental teams to test and iterate on computational designs. S/he will thrive in an entrepreneurial, fast-paced, and highly collaborative start-up environment, with the opportunity to work closely with Flagship Pioneering founders and become a leader in advancing FL106’s scientific platform and patient-focused mission.
Responsibilities:
- Drive the AI/ML computational protein design
- Engage with Pioneering Intelligence at Flagship to explore and implement novel ML models that benefit FL106 design principles
- Advance both antibody engineering and de novo antibody design pipelines
- Collaborate closely with the FL106 experimental scientists to test and iterate on constructs
- Engineer novel functionalities into protein scaffolds, leveraging structural modeling, rational design, and/or directed evolution
- Be abreast of the computational protein design field to advise design and strategic directions for protein engineering, implementing the latest technologies where necessary
- Contribute to strategic direction of the computational team at FL106, helping shape our design platform at the forefront of scientific innovation
- Identify and lead external research relationships with academic and commercial partners
- Report results to scientific team and Flagship Pioneering management
Key Qualifications:
- Ph.D. (with 2+ yrs of industry research experience) in computational protein design, protein biochemistry, computational biophysics, computational biology, physics, or related field
- Expertise in computational protein modeling and design, structural biology, and biophysics is required
- Deep expertise with ML tools for computational protein design such as AlphaFold, RosettaFold, ESMFold, ProteinMPNN, RFDiffusion, Chroma, IgFold, DeepAb, Parapredis is required
- Experience with antibody and/or nanobody modeling and design is strongly preferred.
- Knowledge of critical wet-lab techniques used in protein engineering such as phage display, SPR, ITC, CD-spectroscopy is preferred
- Strategic thinker, able to shift seamlessly between rigorous scientific details and high-level context and implications
- Instinctive team player with excellent communication skills and great attention to detail
About Flagship
Flagship Pioneering is a bioplatform innovation company that invents and builds platform companies, each with the potential for multiple products that transform human health or sustainability. Since its launch in 2000, Flagship has originated and fostered more than 100 scientific ventures, resulting in generation of over 500 patents, initiation of over 50 clinical trials for novel therapeutic agents and an aggregate value of more than $90 billion. Many of the companies Flagship has founded have addressed humanity’s most urgent challenges: vaccinating billions of people against COVID-19, curing intractable diseases, improving human health, preempting illness, and feeding the world by improving the resiliency and sustainability of agriculture. Flagship has been recognized twice on FORTUNE’s “Change the World” list, an annual ranking of companies that have made a positive social and environmental impact through activities that are part of their core business strategies and has been twice named to Fast Company’s annual list of the World’s Most Innovative Companies. Learn more about Flagship at www.flagshippioneering.com.
Flagship Pioneering is committed to equal employment opportunity regardless of race, color, ancestry, religion, sex, national origin, sexual orientation, age, citizenship, marital status, disability, gender identity or Veteran status.
At Flagship, we recognize there is no perfect candidate. If you have some of the experience listed above but not all, please apply anyway. Experience comes in many forms, skills are transferable, and passion goes a long way. We are dedicated to building diverse and inclusive teams and look forward to learning more about your unique background.
Recruitment & Staffing Agencies: Flagship Pioneering and its affiliated Flagship Lab companies (collectively, “FSP”) do not accept unsolicited resumes from any source other than candidates. The submission of unsolicited resumes by recruitment or staffing agencies to FSP or its employees is strictly prohibited unless contacted directly by Flagship Pioneering’s internal Talent Acquisition team. Any resume submitted by an agency in the absence of a signed agreement will automatically become the property of FSP, and FSP will not owe any referral or other fees with respect thereto.
The salary range for this role is $115,000 - $258,500. Compensation for the role will depend on a number of factors, including a candidate’s qualifications, skills, competencies, and experience. FL108 currently offers healthcare coverage, annual incentive program, retirement benefits and a broad range of other benefits. Compensation and benefits information is based on FL108's good faith estimate as of the date of publication and may be modified in the future.
Privacy Notice for Applicants: When you apply for a role at Flagship Pioneering or one of its portfolio companies, we collect and use personal information you provide (such as your name, contact details, work history, and application materials) to evaluate your application, communicate with you, and comply with legal obligations. Your application data is processed through Greenhouse, our applicant tracking system, and may also be reviewed using AI-assisted screening tools. We do not sell your personal information. California residents have rights under the CCPA/CPRA including to know, delete, and opt out of the sharing of their personal information. If you are located in the EU or UK, we process your data under GDPR and you have rights to access, rectify, and erase your data. To exercise your rights or for questions, contact privacy@flagshippioneering.com.
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Apply to Flagship Pioneering, Inc.