Jobs Companies Cogent Biosciences Sr. Manager, Cost Accounting

About this Sr. Manager, Cost Accounting role at Cogent Biosciences

Cogent Biosciences · Onsite · Waltham, Massachusetts, United States

Who We Are:

Cogent Biosciences is a publicly traded biotechnology company focused on developing novel precision therapies to treat a broad range of patients with unmet medical needs. Cogent’s lead program, bezuclastinib, is designed to selectively and potently inhibit exon 17 mutations found within the KIT receptor tyrosine kinase, including KIT D816V. KIT D816V is responsible for driving a rare and serious condition called Systemic Mastocytosis, and exon 17 mutations are also found in patients with gastrointestinal stromal tumors (GIST), a type of cancer with strong dependence on oncogenic KIT signaling. Bezuclastinib has exhibited promising initial data across all three trials: APEX in AdvSM, SUMMIT in NonAdvSM and PEAK in GIST, including an encouraging safety profile across 600+ patients in single agent and combination dosing. 


The Role: Cogent Biosciences is preparing for its first commercial launch and we are seeking a Senior Manager, Cost Accounting to build and maintain the inventory and cost of goods sold processes. This role is responsible for ensuring accurate product costing, inventory valuation, variance analysis, and financial reporting in compliance with U.S. GAAP. This is a hands-on builder role suited for an experienced accountant with an expertise in pharmaceutical industry accounting practices, standard costing methodologies, inventory controls, and designing scalable accounting processes. This position reports to the Commercial Accounting Leader and will partner closely with Supply Chain, FP&A, Quality, Technical Operations, external vendors, and senior finance leadership to support the Company's transition to a commercial-stage organization 


Responsibilities:

  • Develop, implement, and maintain standard cost accounting policy & processes, including performing periodic analyses in support of our standard cost model and the regular investigation, resolution, and reporting of actual-to-standard variances
  • Partner closely with Supply Chain, Quality, and FP&A teams to establish and maintain accurate product costing methodologies
  • Manage accounting processes related to all stages of inventory (raw materials, WIP, finished goods) and ensure appropriate capitalization, standard costing, and variance analyses
  • Complete inventory/cost accounting for month end financial close: enter journal entries, prepare account reconciliations, and provide inventory flux analysis/reporting related to external manufactured product (CMO model) to comply with U.S. GAAP
  • Establish inventory controls and flow charts in coordination with Supply Chain and 3PL partners; align with internal and external auditors on appropriate SOX documentation
  • Manage inventory reconciliations, cycle count programs, physical inventory counts, and inventory reserve analyses to ensure internal controls are functioning as designed
  • Track and monitor inventory movement, capitalization, and reserves (including excess and obsolete inventory), working directly with external vendors to ensure accurate monthly reports
  • Collaborate with the FP&A team to understand gross margin and inventory trends, and provide timely and insightful financial analysis of costs and margins to support budgeting, forecasting, and financial modeling related to manufacturing and inventory costs
  • Provide financial analysis and operational insights regarding inventory performance, margin analysis, and supply chain efficiency to support strategic decision making
  • Develop cost estimates for potential new products and projects in conjunction with the FP&A and Supply Chain teams
  • Drive continuous improvements in inventory accounting processes, ERP system utilization, and reporting

Qualifications:

  • Bachelor’s Degree in Finance or Accounting, required; CPA and/or CMA strongly preferred
  • 6+ years of progressive accounting experience, with significant inventory and cost accounting responsibility within a biotech or pharmaceutical manufacturing environment
  • Biotech/pharmaceutical industry experience, required
  • Deep expertise in manufacturing operations (raw material, drug substance, drug product, packaging, & finished goods), inventory, and cost accounting, and the applicable U.S. GAAP requirements in those areas
  • Strong understanding of SOX controls, design, and implementation, and experience supporting audits and internal control environments
  • Excellent interpersonal and communication skills with the ability to interact effectively across all organizational levels as well as external vendors
  • Demonstrated history of successfully managing multiple tasks with the ability to prioritize appropriately and meet deadlines
  • Excellent analytical problem-solving skills and highly proficient in Excel-based modeling
  • Experience with Netsuite ERP, a plus

Salary Range:

$145,000-$165,000 USD 

Target Bonus: 15%
Exact compensation will vary based on skills, experience, and location.

Our Locations

Waltham, MA: Our headquarters is located in the Greater Boston life sciences community, with an open, collaborative office environment designed to support teamwork and connection. Employees benefit from convenient on-site amenities, including free on-site parking and gym facilities in the building. 

Boulder, CO: Our Boulder location is home to Cogent’s discovery research organization and a key scientific hub with strong leadership based on site. Situated in the greater Denver-Boulder biopharmaceutical corridor, this office plays a central role in advancing our discovery efforts and pipeline. 


Our Offer To You 

At Cogent Biosciences, we offer a competitive salary, bonus, and ongoing stock awards, alongside a benefits package that sets us apart. We cover 100% of medical, dental, and vision premiums for you and your family, and help reduce out-of-pocket costs by funding up to 75% of in-network deductiblesOur benefits also include a 401(k) match with immediate vestinggenerous paid time off, 12 weeks of fully paid parental leave, paid family and medical leave for all employees regardless of location, and company-paid short-term disability coverage for up to 20 weeks. Additional perks like wellness programs, tuition reimbursement, and inclusive family-forming support help you thrive at work and beyond. 

We are proud to be an Equal Opportunity Employer. Our goal is to have a diverse workforce. We do not discriminate on the basis of race, age, color, religion, national origin, gender, sexual orientation, gender identity or expression, veteran status or disability, or any other status protected under federal, state, or local law. All employment is decided on the basis of qualifications, merit, and business need. 

 

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About Cogent Biosciences

Who We Are
 

Cogent Biosciences is a publicly traded biotechnology company focused on developing precision therapies for genetically defined diseases. The most advanced clinical program, bezuclastinib, is a selective tyrosine kinase inhibitor that is designed to potently inhibit the KIT D816V mutation as well as other mutations in KIT exon 17. KIT D816V is responsible for driving systemic mastocytosis (SM), a serious disease caused by unchecked proliferation of mast cells. Exon 17 mutations are also found in patients with advanced gastrointestinal stromal tumors (GIST), a type of cancer with strong dependence on oncogenic KIT signaling. Positive results from registration-directed trials in NonAdvanced SM, Advanced SM and GIST were reported in 2025. In addition, the Cogent Research Team is developing a portfolio of novel targeted therapies to help patients fighting serious, genetically driven diseases targeting mutations in ErbB2, PI3Kα, KRAS and JAK2.

 
Our Team
 

 

See all jobs at Cogent Biosciences →

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