Jobs Companies C the Signs Senior Machine Learning Engineer

About this Senior Machine Learning Engineer role at C the Signs

C the Signs · Boston, Massachusetts, United States

Position Summary

The Machine Learning Engineer will be responsible for the end-to-end development and deployment of Large language and machine learning models, with a primary focus on data preprocessing, model training, and fine-tuning using large-scale healthcare datasets. This role requires a strong understanding of Large language models, machine learning principles, data engineering, and experience working with sensitive healthcare data.

Key Responsibilities

  • Data Preprocessing: Clean, transform, and prepare large, complex healthcare datasets for machine learning model development. This includes handling missing values, outlier detection, feature engineering, and data normalization. Identify, collect, and curate relevant, industry-specific datasets for model retraining. Format data appropriately for the chosen LLM and training pipeline
  • Model Training & Fine-Tuning: Design, train, and fine-tune various LLMs on extensive healthcare data to solve specific clinical or operational problems. Set up and manage the training environment, including GPU instances and required software. Train and fine-tune pre-trained LLMs on the custom dataset to achieve specific goals. Experiment with and fine-tune hyperparameters such as learning rate, batch size, and training epochs to optimize model performance. Integration of structured + unstructured data (multi-modal/multi-input models)
  • Model Evaluation & Optimization: Evaluate model performance using appropriate metrics, identify areas for improvement, and implement optimization strategies.
  • Pipeline Development: Develop and maintain robust and scalable data and ML pipelines for model training, inference, and deployment.
  • Collaboration: Work closely with data scientists, clinicians, and software engineers to understand requirements, integrate models into production systems, and ensure data privacy and security compliance.
  • Research & Development: Stay up-to-date with the latest advancements in machine learning and healthcare AI, and explore new technologies and methodologies to enhance our solutions.
  • Documentation: Maintain clear and comprehensive documentation of models, data pipelines, and experimental results.

Requirements

  • Education: Bachelor's or Master's degree in Computer Science, Machine Learning, Artificial Intelligence, or a related quantitative field.
  • Experience:
    • 5+ years of experience in Machine Learning Engineering or a similar role.
    • Proven experience with large-scale data preprocessing, LLM/model training, and fine-tuning.
    • Experience with distributed training (PyTorch Distributed, DeepSpeed, Ray, Hugging Face Accelerate).
    • Experience with GPU/TPU optimization, memory management for large language models.
    • Experience working with healthcare data is highly desirable.
  • Technical Skills:
    • Proficiency in Python and relevant ML libraries (e.g., TensorFlow, PyTorch, Scikit-learn, Pandas, NumPy).
    • Strong understanding of various machine learning algorithms,Large Language Models, and deep learning architectures.
    • Experience with cloud platforms (e.g., GCP, AWS) and distributed computing frameworks (e.g., Spark) is a plus.
    • Familiarity with MLOps practices and tools.
  • Soft Skills:
    • Excellent problem-solving and analytical skills.
    • Strong communication and collaboration abilities.
    • Ability to work independently and as part of a team in a fast-paced environment.
  • Work Authorization:
      • Must be a US Citizen, Green Card holder, or currently in the US have valid H1B visa

Benefits

Why Join Us?

Joining C the Signs is not just about building AI; it’s about shaping the future of healthcare. If you are a technical leader with an unshakable belief in the power of AI to save lives and the ability to make it happen at scale, this is your opportunity to create a tangible, global impact.

Benefits:

  • Competitive salary and benefits package.
  • Flexible working arrangements (remote or hybrid options available).
  • The opportunity to work on life-changing AI technology that directly impacts patient outcomes.
  • Join a team that combines cutting-edge innovation with a mission to save lives and improve health equity.
  • Continuous learning opportunities with access to the latest tools and advancements in AI and healthcare.
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About C the Signs

C the Signs is transforming how the world finds cancer early. Founded by NHS doctors, we combine clinical science, advanced AI and real world evidence to identify cancer risk for patients, providers and entire populations.

At the heart of our work is a simple belief: everyone deserves the chance to survive cancer. Our platform analyses information from both patient-reported data and electronic health records, bringing together thousands of data points to understand a person’s risk and guide them to the right diagnostic pathway, at the right time. It is built to support clinicians in decision making, empower patients with clarity and help health systems act earlier and more effectively.

Today, we have completed more than 500,000 cancer risk assessments and helped identify over 65,000 patients with cancer across 100 cancer types. These are not just numbers. They are people who reached diagnosis sooner and were given more time, more options and more hope.

Used across the UK and soon launching across the United States, C the Signs delivers 99 percent sensitivity and strong clinical accuracy. We help clinicians make informed decisions, improve access for underserved communities and ensure that early detection becomes a lived reality rather than a distant ideal.

C the Signs is building a future where early cancer detection is accessible, equitable and centred on the people it serves.

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