The Position

We are seeking a detail-oriented Scientist to work in the Non-Clinical Development department overseeing bioanalytical work for Maze. In this role, you will oversee bioanalysis for Good Laboratory Practices (GLP), Good Clinical Laboratory Practices (GCLP), and non-GLP studies in support of the development of small molecule drugs. As part of the Non-Clinical Development team, you will have the opportunity to contribute to key drug discovery and development projects. 

This position reports to VP, Non-Clinical Development. 

The Impact You’ll Have

• Oversee the development, validation, and execution of bioanalytical assays for both pharmacokinetics and pharmacodynamics for ongoing preclinical, nonclinical, and clinical programs. 

• Manage the collaborations with contractor laboratories conducting bioanalysis and review data from analysis to confirm analyses were correctly conducted and batch analyses met acceptance criteria. 

• Provide written summaries of bioanalytical methods for regulatory submissions as needed. 

• Coordinate regulated bioanalysis activities across development programs, ensuring compliance with timelines and regulatory standards. 

• Provide timeline updates to the Head of Bioanalysis, Nonclinical Development, and collaborate with key stakeholders in Research, Regulatory Affairs, Manufacturing, Quality, and Clinical Sciences to address bioanalysis-related project issues. 

• Review, investigate, and coordinate resolution of study queries with contract research organization (CRO) and personnel regarding data integrity. 

What We’re Looking For

• Bachelor’s degree in analytical chemistry, chemistry, biochemistry, or related field. 

• 6+ years of relevant experience, ideally within a pharmaceutical company, a CRO, or academia, with a focus on bioanalysis oversight. 

• Experience and understanding of GLP and GCLP principles and guidances 

• Experience in GLP and GCLP analysis of one or more bioanalytical techniques, including: LC-MS/MS, ELISA, and MSD 

• Experience working with multidisciplinary project teams, driving successful outcomes. 

• Ability to manage multiple projects simultaneously with excellent attention to detail. 

• Clear and effective communication skills to present complex scientific information to various stakeholders. 

About Maze Therapeutics

Maze Therapeutics is a clinical-stage biopharmaceutical company harnessing human genetics to develop precision medicines for patients with kidney and metabolic diseases. Our clinical pipeline is anchored by two small molecule programs: MZE829, an APOL1 inhibitor for patients with APOL1‑mediated kidney disease, and MZE782, which targets genetic drivers of disease in phenylketonuria (PKU) and chronic kidney disease. We are also advancing a preclinical pipeline through our Compass platform, which links human genetic variants to the biological pathways that drive disease.

Our People

Maze is comprised of a team of passionate and creative professionals committed to discovering and delivering transformative medicines to patients suffering from both rare and common genetic diseases. We are fostering a culture that encourages vision, initiative and the development of talent. Our supportive work environment inspires creative thinking and freedom of expression, resulting in a stimulating atmosphere where people enjoy coming to work. While we have a passion for advanced science and pride ourselves on excellence in execution, ultimately, everything we do is about patients. 

Our Core Values

Further Together – Our path is paved with challenges, but with resilience and a team-first mentality, we’ll achieve our mission. 

Impact Obsessed – We embrace the bold, take calculated risks, and learn from our mistakes to improve the lives of others.

Stand True – Our integrity is foundational; it guides us no matter the obstacle.

The expected annual salary range for employees located in the San Francisco Bay Area is $130,000 - $159,000. Additionally, this position is eligible for an annual performance bonus.

Maze performs position-based compensation benchmarking to industry market data to ensure we pay competitive wages. Determination of starting salary will depend upon a variety of job-related factors, which may include professional experience, skills, and job location. The expected salary range for this role may be modified in the future.

Maze offers a robust benefits package to our eligible employees including competitive medical, dental, and vision insurance, mental health offerings, equity incentive plan, 401(k) program with employer match and a generous holiday and PTO policy.

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