Job Description:

Company Overview

Founded over a decade ago, CRISPR Therapeutics is a leading biopharmaceutical company focused on developing transformative gene-based medicines for serious human diseases. The Company has evolved from a pioneering research-stage organization into an industry leader, marking a historic milestone with the approval of CASGEVY® (exagamglogene autotemcel [exa-cel]), the world’s first CRISPR-based therapy, approved for eligible patients with sickle cell disease and transfusion-dependent beta thalassemia. CRISPR Therapeutics is advancing a broad and diversified pipeline across hemoglobinopathies, cardiovascular, autoimmune, oncology, regenerative medicine and rare diseases. The Company continues to expand its leadership in gene editing through the development of SyNTase™ editing, a novel and proprietary gene-editing platform designed to enable precise, efficient, and scalable gene correction. To accelerate and expand its impact, CRISPR Therapeutics has established strategic collaborations with leading biopharmaceutical partners, including Vertex Pharmaceuticals. CRISPR Therapeutics AG is headquartered in Zug, Switzerland, with its wholly-owned U.S. subsidiary, CRISPR Therapeutics, Inc., and R&D operations based in Boston, Massachusetts and San Francisco, California.

Position Summary

The Senior Specialist, Site Supply Chain Planning is responsible for establishing and maintaining material replenishment strategies to support the Internal Manufacturing and Quality Control schedules.  This role collaborates with site and network stakeholders to ensure the uninterrupted supply of direct and indirect production materials.  The incumbent will support operational readiness through the development of material forecasts, risk mitigation plans, and quality inspection queue oversight. 

In support of site procurement activities, the Senior Specialist, Site Supply Chain Planning creates and manages vendor purchase orders.  This role will maintain purchasing data in the Oracle Supply Chain Management module and drive projects to advance the supply chain systems roadmap.  

As a member of Site Supply Chain, you will directly support materials management, site planning, procurement, supply chain systems, and compliance.    

Responsibilities

• Establish and manage material replenishment programs at the site.    
• Maintains vendor and procurement data within the Oracle SCM module.  Monitors and adjusts replenishment parameters.
• Proactively works with vendors to maintain lead times, pricing files, identify risks, and optimize stocking levels.
• Create, track, and manage purchase orders.   
• Develops raw material, consumable, and production supply forecasts.  Collaborates with network planning to connect site and network priorities.
• Drives planning and procurement for raw materials, consumables, process aids, and production supplies.
• Management of Leukopak procurement.
• Monitor the quality inspection queue and manage priorities with cross-functional stakeholders (Manufacturing, Quality Control, and Quality Assurance).
• Collaborate with the warehouse to resolve documentation or vendor related issues related to receipt, release, or material supply.
• Support the department and site QMS through effective management of deviations, CAPA’s, and change controls.
• Maintain, update, and improve applicable Site Supply Chain procedures and documentation.
• Participate in the development of scenario planning and production scheduling activities to drive operational readiness.
• Manage transfers, chain of custody, and replenishment planning between Framingham warehouse and third-party storage partners. 
• Provides subject matter expert reviews of Supplier Change Notifications and assists with the development of impact assessments.
• Supports the raw material program from material onboarding through lot release.
• Assist stakeholders through the material onboarding process and provide review and subject matter approval for material specifications and onboarding documents. 
• Drives the supply chain systems roadmap through the completion of projects related to inventory control, master data, BOM lifecycle management, workflow planning, WMS, and material replenishment.

Minimum Qualifications

• College degree or equivalent professional experience and Minimum of 5-7 years’ experience in a related supply chain discipline; inventory management, planning, procurement, or warehouse operations.
• Or high school / associate degree or higher and minimum of 8-10+ years’ experience in a related supply chain discipline.
• Minimum of 3 years’ experience working within a cGMP environment.
• Advanced knowledge of ERP and WMS systems (Oracle preferred).
• Solid computer skills (Microsoft Office Suite) required.
• Well organized, strong communication skills, and drives for results.

Preferred Qualifications

• Bachelor’s degree in business, supply chain, operations management, or related field.
• APICS CPIM or CSCP preferred.
• In-depth knowledge of GMP operations.
• Demonstrates growing knowledge of regulatory compliance (FDA, GMP, etc.) in a biotech setting.
• Previous experience procuring raw materials and consumables in a cGMP environment.
• Comprehensive understanding of Inventory Management concepts. 
• Works independently, exercises sound judgment when troubleshooting.  

Competencies

• Collaborative – Openness, One Team
• Undaunted – Fearless, Can-do attitude
• Results Orientation – Delivering progress toward our mission. Sense of urgency in solving problems.
• Entrepreneurial Spirit – Proactive. Ownership mindset.

Our manufacturing positions are located fully on-site at our Framingham manufacturing facility.

Senior Specialist: Base pay range of $110,000 to $120,000+ bonus, equity and benefits

The range provided is CRISPR Therapeutics’ reasonable estimate of the base compensation for this role. The actual amount will be based on job-related and non-discriminatory factors such as experience, training, skills, and abilities.

CRISPR Therapeutics, Inc. is committed to equal employment opportunity and non-discrimination for all employees and qualified applicants without regard to a person's race, color, gender, age, religion, national origin, ancestry, disability, veteran status, genetic information, sexual orientation or any characteristic protected under applicable law.

To view our Privacy Statement, please click the following link: http://www.crisprtx.com/about-us/privacy-policy