Senior Principal – Oncology

Locations: GSK HQ,  New Oxford Street, London, UK & Pennsylvania - Upper Providence, USA

We create a place where people can grow, be their best, be safe, and feel welcome, valued and included. We offer a competitive salary, an annual bonus based on company performance, healthcare and wellbeing programmes, pension plan membership, and shares and savings programme.

We embrace modern work practises; our Performance with Choice programme offers a hybrid working model, empowering you to find the optimal balance between remote and in-office work.

Discover more about our company wide benefits and life at GSK on our webpage Life at GSK | GSK

Position Summary:
Join a talented and committed team at GSK, where your expertise will help shape the future of healthcare. In this Senior Principal role, you will lead complex projects by collaborating closely with cross-functional teams to deliver scientific and strategic solutions. We value curious, motivated individuals who enjoy tackling challenges and driving meaningful impact. This is your chance to grow your career while contributing to GSK’s mission of uniting science, technology, and talent to get ahead of disease together.

Key Responsibilities:

This role will provide YOU the opportunity to lead key activities to progress YOUR career. These responsibilities include some of the following:

• Lead the design, execution, and interpretation of scientific and clinical strategies to advance key projects.
• Collaborate with internal teams and external partners, ensuring clear communication and effective decision making.
• Provide expert guidance to cross-functional teams on scientific, technical, and regulatory matters.
• Drive innovation by identifying opportunities for new approaches and improved methodologies.
• Mentor and support colleagues to build capability and promote a positive team culture.
• Ensure project deliverables meet quality standards and timelines aligned with business goals.

Why You?
Basic Qualifications & Skills:
We are seeking professionals with these required skills to help us achieve our goals:

• Advanced degree (Master’s or PhD) in a relevant scientific, technical, or clinical discipline.
• Significant experience (typically 8+ years) in the pharmaceutical or healthcare industry.
• Proven ability to lead complex scientific or clinical projects with cross-functional teams.
• Strong communication skills with the ability to present complex information clearly.
• Demonstrated problem-solving skills and a proactive mindset.
• Willingness to work in a hybrid model, combining on-site presence in the United Kingdom and remote work.

Preferred Qualifications & Skills:

Please note the following skills are not necessary, just preferred, if you do not have them, please still apply:

·       Experience leading large, multi-disciplinary projects in a global environment.

·       Background in developing and implementing innovative scientific strategies.

·       Understanding of regulatory requirements and experience working with regulatory agencies.

·       Track record of mentoring and developing team members.

·       Comfortable collaborating across different cultures and disciplines.

·       Passionate about fostering an inclusive environment where all voices are heard.

Closing Date for Applications – 10th November 2026

Please take a copy of the Job Description, as this will not be available post closure of the advert. 

When applying for this role, please use the ‘cover letter’ of the online application or your CV to describe how you meet the competencies for this role, as outlined in the job requirements above. The information that you have provided in your cover letter and CV will be used to assess your application.

At GSK, we have bold ambitions for patients, aiming to positively impact the health of 2.5 billion people by the end of the decade. Our R&D focuses on discovering and delivering vaccines and medicines, combining our understanding of the immune system with cutting-edge technology to transform people’s lives. GSK fosters a culture ambitious for patients, accountable for impact, and committed to doing the right thing, making sure that we focus our efforts on accelerating significant assets that meet patients’ needs and have the highest probability of success. We’re uniting science, technology, and talent to get ahead of disease together.

Find out more:  

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Why GSK?

Uniting science, technology and talent to get ahead of disease together.

GSK is a global biopharma company with a purpose to unite science, technology and talent to get ahead of disease together. We aim to positively impact the health of 2.5 billion people by the end of the decade, as a successful, growing company where people can thrive.

We get ahead of disease by preventing and treating it with innovation in specialty medicines and vaccines. We focus on four therapeutic areas: respiratory, immunology and inflammation; oncology; HIV; and infectious diseases – to impact health at scale.

People and patients around the world count on the medicines and vaccines we make, so we’re committed to creating an environment where our people can thrive and focus on what matters most. Our culture of being ambitious for patients, accountable for impact and doing the right thing is the foundation for how, together, we deliver for patients, shareholders and our people.

GSK is an Equal Opportunity Employer. This ensures that all qualified applicants will receive equal consideration for employment without regard to race, color, religion, sex (including pregnancy, gender identity, and sexual orientation), parental status, national origin, age, disability, genetic information (including family medical history), military service or any basis prohibited under federal, state or local law.

We believe in an agile working culture for all our roles. If flexibility is important to you, we encourage you to explore with our hiring team what the opportunities are.

Should you require any adjustments to our process to assist you in demonstrating your strengths and capabilities contact us at [email protected] where you can also request a call.

Please note should your enquiry not relate to adjustments, we will not be able to support you through these channels. However, we have created a Recruitment FAQ guide. Click the Link where you will find answers to multiple questions we receive

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