Über diese Senior Associate Scientist, Upstream Process Development — Bioprocess Automation & Digitization Stelle bei Pfizer
What You Will Achieve
A Senior Associate Scientist position is available in the Upstream Process Development group within the Bioprocess R&D organization in Andover, MA.
This is a mixed scientist–developer role: roughly half your time will be spent in the lab running mammalian cell culture processes, and half building the software that automates and controls them.
You will join a team of scientists and engineers developing manufacturing processes for recombinant proteins and other modalities for early- and late-phase human clinical trials. You will also be a core contributor to our in-house bioprocess automation and digitization platform — an OPC UA-based system that connects bioreactors, analyzers, and PAT instruments to real-time control logic and data infrastructure across multiple Pfizer development and manufacturing sites. Your focus is the application layer: high-level control strategies, instrument drivers, and integration into live lab operations.
You will work alongside dedicated automation and controls engineers who own the underlying infrastructure, vendors that own the equipment you’ll control, and scientists who consume your products. We need someone fluent on all sides of that equation — who understands the cell culture process well enough to say what a control scheme should do, knows the equipment well enough to know whether it can, develops the software that does it, and can hold a productive technical conversation with the engineers who own the infrastructure.
How You Will Achieve It
- Translate process understanding into control requirements; develop, test, and deploy control schemes, alarms, and UI elements on the platform
- Design, execute, and troubleshoot experiments in appropriate scale-down models such as shake flasks and bench-top or high-throughput bioreactors
- Serve as technical owner and subject matter expert for one or more instrument platforms — bioreactor control systems, automated cell counters, Raman and capacitance probes, and high-throughput systems — including the integration work that brings them onto the platform
- Support what you build end to end — version control, code review, testing, deployment, monitoring, and support — and work with fellow scientists as a digital SME to troubleshoot and continuously improve the platform
- Contribute to a safe, efficient, and harmonious lab environment; strong lab citizen and collaborative team player
Qualifications
Must Have
- Bachelor’s degree with 2–4 years’ industrial experience, or Master’s degree with 0–2 years’ industrial experience in Chemical Engineering, Bioengineering, Biomedical Engineering, Cell Biology, Computer Science, Electrical Engineering, Mechanical Engineering or a relevant field
- Working knowledge of at least one programming language, plus something substantial you have built and delivered. Not coursework, not a tutorial - published source code is very welcome
- Hands-on laboratory experience. This could include cell culture or protein purification experience in an academic or industrial lab.
- Self-motivated and organized, with excellent attention to detail, strong written and verbal communication including the ability to explain technical decisions to colleagues who do not write code, and the ability to adapt to a fast-paced environment with shifting priorities
Nice to Have
Our strongest candidates are experienced in two of these and conversant in the rest. These are examples of what competence looks like, not requirements — nobody is expected to have all of it.
Software engineering
- Application and backend development — Any programming language, Git, Streamlit, REST APIs, async programming
- Databases and data engineering — PostgreSQL, Snowflake, Elasticsearch, time-series stores, message brokers, streaming or ETL pipelines
- Infrastructure and operations — can read a Dockerfile, can debug a deployed service, comfortable in Linux, can build in Github Actions
Hardware-Software integration
- OPC UA, Modbus, serial/TCP interfaces, or similar industrial communication protocols
- Embedded and hardware integration— microcontrollers, firmware, device drivers, sensor interfacing
- Exposure to PLC or DCS environments such as DeltaV, Rockwell, or Siemens, and/or middleware such as Kepware
Bioprocess and cell culture
- Setup, operation, and troubleshooting of fed-batch and/or perfusion bench-top or high-throughput bioreactor platforms, including bench-scale and AMBR systems
- Experience developing and implementing process control strategies, including real-time monitoring, integration of PAT and analytical instruments, and data-driven process optimization
Lab Instrumentation
- Practical experience operating and supporting laboratory instrumentation, including analytical, bioreactor, automation, or process control systems.
- Proven ability to partner with vendors to troubleshoot issues, evaluate technologies, and influence product enhancements based on user requirements.
PHYSICAL/MENTAL REQUIREMENTS
- Lifting, sitting, standing, walking, bending, ability to perform mathematical calculations and ability to perform complex data analysis
NON-STANDARD WORK SCHEDULE, TRAVEL OR ENVIRONMENT REQUIREMENTS
- May require occasional work on the weekend for essential tasks
- May need to travel occasionally to attend internal meetings or external conferences
Work Location Assignment: On Premise
Relocation assistance may be available based on business needs and/or eligibility.
Candidates must be authorized to be employed in the U.S. by any employer.
U.S. work visa sponsorship (such as TN, O-1, H-1B, etc.) is not available for this role now or in the future.
Sunshine Act
Pfizer reports payments and other transfers of value to health care providers as required by federal and state transparency laws and implementing regulations. These laws and regulations require Pfizer to provide government agencies with information such as a health care provider’s name, address and the type of payments or other value received, generally for public disclosure. Subject to further legal review and statutory or regulatory clarification, which Pfizer intends to pursue, reimbursement of recruiting expenses for licensed physicians may constitute a reportable transfer of value under the federal transparency law commonly known as the Sunshine Act. Therefore, if you are a licensed physician who incurs recruiting expenses as a result of interviewing with Pfizer that we pay or reimburse, your name, address and the amount of payments made currently will be reported to the government. If you have questions regarding this matter, please do not hesitate to contact your Talent Acquisition representative.
EEO & Employment Eligibility
Pfizer is committed to equal opportunity in the terms and conditions of employment for all employees and job applicants without regard to race, color, religion, sex, sexual orientation, age, gender identity or gender expression, national origin, disability or veteran status. Pfizer also complies with all applicable national, state and local laws governing nondiscrimination in employment as well as work authorization and employment eligibility verification requirements of the Immigration and Nationality Act and IRCA. Pfizer is an E-Verify employer. This position requires permanent work authorization in the United States.
Pfizer endeavors to make www.pfizer.com/careers accessible to all users. If you would like to contact us regarding the accessibility of our website or need assistance completing the application process and/or interviewing, please email [email protected]. This is to be used solely for accommodation requests with respect to the accessibility of our website, online application process and/or interviewing. Requests for any other reason will not be returned.
To learn more about acceptable and prohibited uses of AI during the recruitment process, please review our candidate AI-use guidelines available on Pfizer Careers.
Research and Development