Über diese Senior Associate Scientist - Process Development Stelle bei Pfizer
Why Patients Need You
Pfizer’s purpose is to deliver breakthroughs that change patients’ lives. Process Development is at the heart of fulfilling this purpose as we translate advanced science into streamlined, robust processes that deliver medicines to patients globally.
What You Will Achieve
As a Senior Associate Scientist within the Early Bioprocess Development (EBPD) group in the Vaccines organization, you will apply cutting-edge technologies to accelerate the development of high-quality protein subunit vaccines. This role is highly technical and collaborative, requiring deep hands-on expertise in molecular biology, cell culture, and data-driven process optimization.
Your goals will be:
Optimize cell line development workflows to improve subunit protein expression, overall productivity, process efficiency and biological robustness of the production systems
Execute fermentation to characterize key performance indicators including cell fitness, growth, recovery, protein production yield, protein purity etc.
Perform data analysis to identify patterns, establishing quantitative correlations between input parameters such as DNA sequences and output values such as protein yield and quality.
Present experimental data and strategic conclusions at cross-functional meetings, contributing to team-wide knowledge sharing.
How You Will Achieve It
Collaborating with multi-disciplinary teams and working closely with the cell culture, purification, mRNA production and analytical groups.
Maintain impeccable, timely records in Electronic Laboratory Notebooks (ELNs) and author comprehensive technical/production reports.
Draft, review, and contribute to internal technical reports and external scientific publications.
Contribute to building a culture that embraces excellence, urgency, partnerships with key stakeholders, continuous learning and improvement, increasing technical skill base and other cross-functional expertise.
Ensure all tasks and responsibilities are carried out according to scientific, ethical and regulatory standards.
Qualifications
Must-Have
B.S. degree with 3 to 5 years of relevant industry or research experience, or M.S. in bioengineering, biochemistry, chemical engineering or related fields with 0 to 3 years of experience
Experience in aseptic cell culture techniques, including cell passaging and maintenance, transfection, monitoring cell morphology and viability.
Experience in using flow cytometry, and cell sorting cytometers as well as flow cytometry analysis software such as FlowJo.
Knowledge and hands-on experience in molecular biology techniques including DNA/RNA extraction, PCR, ddPCR, RT-PCR, ligation, cloning, transformation, gel electrophoresis, SDS-PAGE, western blot, ELISA.
Well organized, self-motivated, team-oriented with high attention to detail.
Strong collaborative spirit and communication skills.
Nice-to-Have
Experience in setting up, feeding, sampling and controlling benchtop or single-use bioreactors (batch, fed-batch)
Hands-on knowledge and experience with NGS sequencing platforms.
OTHER JOB DETAILS
Work Location Assignment: On site
Relocation assistance may be available based on business needs and/or eligibility.
Candidates must be authorized to be employed in the U.S. by any employer.
U.S. work visa sponsorship (such as TN, O-1, H-1B, etc.) is not available for this role now or in the future.
Sunshine Act
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EEO & Employment Eligibility
Pfizer is committed to equal opportunity in the terms and conditions of employment for all employees and job applicants without regard to race, color, religion, sex, sexual orientation, age, gender identity or gender expression, national origin, disability or veteran status. Pfizer also complies with all applicable national, state and local laws governing nondiscrimination in employment as well as work authorization and employment eligibility verification requirements of the Immigration and Nationality Act and IRCA. Pfizer is an E-Verify employer. This position requires permanent work authorization in the United States.
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Research and Development