Job Title

Job Description

An exciting opportunity is available for a Research Assistant (Medicinal Chemist) to join the Lessene Laboratory in the Technological Sciences Division at Australia’s pre-eminent biomedical research institute. This position will be part of an exciting new start-up, Synerva Therapeutics.

About the Position

Synerva Therapeutics Ltd, a WEHI start-up, is dedicated to transforming the treatment landscape for Parkinson’s disease. Synerva leverages cutting-edge insights in neurobiology to design and develop first-in-class small-molecule therapies to stop neurons from dying in neurodegenerative diseases. By targeting the underlying molecular drivers of neurodegeneration, Synerva aims to move beyond symptomatic relief toward disease-modifying solutions.

Our multidisciplinary team partners with clinicians and lived experience to ensure we are scientifically rigorous, translationally-focused and patient-centred. The company aspires to develop treatments that can meaningfully improve outcomes and redefine what is possible for individuals living with Parkinson’s disease and related neurodegenerative conditions. 

Reporting to the Laboratory Head, the Research Assistant (medicinal chemistry) will be part of the team developing small molecule leads to treat Parkinson’s and related neurodegenerative diseases.

This laboratory-based role will work closely with other members of Synerva and the Lessene lab and will be expected to conduct milestone-oriented research in alignment with the Synerva project plan. Embedded within a commercially focused program, the role offers the opportunity to contribute to translational research with real-world impact. While publication opportunities may arise, these will align with commercial priorities.

Selection Criteria
Essential Knowledge and Skills:

• BSc with Honours in a relevant area of study (e.g. organic chemistry, chemical biology, medicinal chemistry) and subsequent laboratory research experience.

• Basic computer skills and ability to accurately record data, results and the development of new methods and theories.

• Project management, excellent oral and written communication and reporting skills.

• Demonstrated theoretical knowledge and practical skills in organic chemistry.

• Experience in the synthesis, purification and characterisation of small molecules.

• Demonstration of good lab practices, with particular attention to safety.

Desirable Knowledge and Skills:

• Familiarity with the principles of medicinal chemistry in the optimisation of lead compounds.

• Experience working in commercial academic projects, biotech, pharma or start-up environments

• Understanding of confidentiality and intellectual property

Personal Qualities:

• Good communication skills and the ability to work constructively within a team environment.

• Ability to work as part of a team using experimental protocols.

• Excellent attention to detail and record keeping, ensuring that data, new methods and theories are accurate, of high-quality and accessible to other researchers.

• Highly motivated, reliable and approachable, with strong organisation skills, and the ability to manage time effectively and meet deadlines (including research milestones).

• Willing to learn, take direction and have progress reviewed where required.

Terms of Appointment
This position is available on a full-time basis for an initial period of one year with the potential extension, contingent on funding. Applications from candidates seeking a minimum appointment of 0.6 FTE will also be considered. Salary is Research Support Employee Level 5 ($84,479 - $97,036), commensurate with qualifications and experience. Very attractive salary packaging options are available for general living expenses, meal entertainment, novated leasing and more. 12% superannuation payable, plus up to a further 5% after the first 6 months of service via our matching superannuation scheme.

General enquiries can be directed to Chris Gardner – [email protected]
A position description is available here.

How to Apply
Please apply by uploading your CV, cover letter and a document addressing the key selection criteria in pdf format.

Application Closing Date: Thursday 8 October 2026.