About the Team: 

Enterprise Systems is the backbone of GSK’s internal operations in Digital & Tech, enabling GSK Global Functions teams such as Finance, Procurement, HR, Legal, Compliance, (Workplace & Real Estate Facilities) WREF, (Communications & Government Affairs) CGA and Corporate Secretariat to run seamlessly. This team designs and delivers cutting-edge digital platforms that power critical processes, ensuring efficiency, compliance, and scalability across the enterprise. Enterprise Systems Management & Business Operations delivers digital solutions that support Enterprise Systems running as a high-performing organisation. This team drives financial discipline, operational rigour and strategic alignment across the (Enterprise Systems) ES portfolio that safeguard GSK’s integrity and reputation globally. By joining this team, you’ll help shape systems that support thousands of employees worldwide, driving innovation and reliability in the tools that keep GSK moving forward

Job Purpose:

The Principal Developer – Aspen designs, develops, tests, and supports (Manufacturing Execution System) MES solutions using Aspen Manufacturing Suite. The role translates business and manufacturing requirements into reliable, secure, and compliant system solutions, including configurations, databases, integrations, and custom applications. The role supports troubleshooting of complex technical issues, uses approved AI-assisted development tools to improve efficiency, and ensures all solutions meet quality, security, data integrity, and (Good Practice) GxP requirements. The Principal Developer - Aspen also promotes standardization, reusable solutions, and best practices across MES platforms and teams.

Key Responsibilities:

• Design, configure, develop, and implement MES solutions using Aspen Manufacturing Suite.  
• Translate business and manufacturing requirements into technical solutions by developing and maintaining system integrations, database objects, and custom applications to support business needs.
• Perform testing, deployment, and validation activities to ensure system reliability and compliance.  
• Troubleshoot and resolve MES application issues and provide production support.  
• Use approved development and AI-assisted tools to improve productivity and solution quality.  
• Ensure compliance with GxP, data integrity, cybersecurity, and company standards.  
• Create and maintain technical documentation, design specifications, and support materials.  
• Contribute to standardization, best practices, and continuous improvement initiatives.  
• Collaborate with business users, project teams, and vendors to successfully deliver MES projects while providing technical guidance, mentoring, and knowledge sharing to team members.  
• Participate in system upgrades, enhancements, and lifecycle management activities 
• Develop expertise across MES platforms, software technologies, and AI tools to effectively support and deliver solutions across multiple MES systems 
• Use AI-assisted development as the default way of coding, testing, reviewing and documenting, and validate all AI-generated output for quality, security, data integrity and GxP before release. 
• Implement version control and automated build, test, and deployment practices where supported, achieving improved release quality and deployment efficiency. Monitor production performance, proactively identify and eliminate root causes of issues, reducing recurring incidents and improving system reliability and availability. 
  

Basic Qualifications:

• Bachelor’s or master’s degree in engineering, Computer Science, Information Technology, Automation, Data, Life Sciences or a relevant technical discipline, or equivalent practical experience.
• Relevant technical, AI, cloud, integration, automation, data, validation, cyber security or engineering certifications.
• Minimum 7+ years of hands-on technical engineering experience in complex enterprise or operational technology environments.
• Experience in Aspen Manufacturing Suite MES and the ability to work across multiple MES platforms.
• Experience in leading MES solution delivery across products, platforms and sites.
• Experience in software development, database technologies and system integrations within manufacturing or enterprise environments.
• Experience in industrial connectivity technologies such as OPC UA (Unified Architecture)/OPC HDA (Historical Data Access) and manufacturing system integrations.
• Experience in technical review, troubleshooting and root-cause analysis.
• Experience in coordinating cross-functional teams and vendors to deliver compliant solutions that can be operated and scaled.
• Experience in managing technical risk, ensuring data integrity, GxP compliance and supporting audits and inspections.
• Experience in mentoring engineers and supporting technical best practices and standardisation.
• Experience in using AI-assisted development tools and applying software quality, security, compliance and maintainability controls.
  

Preferred Qualifications:

• Experience in problem-solving, technical leadership and communication.
• Experience in developing solution designs, managing technical documentation and supporting compliant system delivery.
• Experience in integrations, data management, security, quality and change control processes.
• Experience in collaborating across teams, mentoring engineers and supporting standardisation, automation and continuous improvement.

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Why GSK?

Uniting science, technology and talent to get ahead of disease together.

GSK is a global biopharma company with a purpose to unite science, technology and talent to get ahead of disease together. We aim to positively impact the health of 2.5 billion people by the end of the decade, as a successful, growing company where people can thrive. We get ahead of disease by preventing and treating it with innovation in specialty medicines and vaccines. We focus on four therapeutic areas: respiratory, immunology and inflammation; oncology; HIV; and infectious diseases – to impact health at scale.

People and patients around the world count on the medicines and vaccines we make, so we’re committed to creating an environment where our people can thrive and focus on what matters most. Our culture of being ambitious for patients, accountable for impact and doing the right thing is the foundation for how, together, we deliver for patients, shareholders and our people.

Inclusion at GSK:

As an employer committed to Inclusion, we encourage you to reach out if you need any adjustments during the recruitment process.

Please contact our Recruitment Team at [email protected] to discuss your needs.

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