The Ikegami lab at Cincinnati Children’s Hospital Medical Center is recruiting highly motivated postdoctoral fellows to investigate nuclear and chromatin organization and dynamics in development, homeostasis, and disease. Ongoing projects focus on defining the mechanisms and functional consequences of nuclear mechanosensing, nuclear envelope damage and repair, and nuclear lamina–chromatin interactions in developmental and degenerative contexts.

Applicants interested in extending these research areas to development, disease, and aging in cardiovascular, muscular, and nervous systems are encouraged to apply. The lab employs a multidisciplinary approach that integrates functional genomics, quantitative cell biology, mathematical modeling, mouse genetics and disease models, and bioinformatics. Prior experience in quantitative biology, functional genomics, or cardiovascular biology is beneficial but not required.

Cincinnati Children’s Hospital Medical Center provides a strong research environment with investigators focused on mechanisms of organismal development and disease. This position offers extensive opportunities for collaboration within and beyond the institution.

MAJOR DUTIES AND RESPONSIBILITIES:  

•    Design, execute, and record laboratory experiments, and analyze the data.

•    Research and improve current methods and evaluate innovative techniques. Implement this knowledge in the Division/Department.

•    Present research at laboratory meetings, journal clubs, seminars, and meetings.

•    Draft, write, and edit scientific reports, papers, journal articles, abstracts, and grants.

•    Maintain currency in field through continuing education, literature, and seminars.  

•    Attend required Cincinnati Children’s training sessions and ensure regulatory compliance with all policies and procedures.

•    Perform other duties as assigned.

EDUCATION/EXPERIENCE

REQUIRED

•    Ph.D. in related discipline, MD, or equivalent required.

REQUIRED SKILLS:  Excellent written, verbal, and interpersonal communication skills.  Demonstrate attention to detail, strong organizational skills, supervisory ability, and an innovative approach to experimental design.  Computer literate and working knowledge of software applications (word processing, spreadsheet, and database). Analytical ability sufficient to compare data; mathematical ability sufficient to perform algebraic calculations and statistical analysis.  Ability to synthesize information and to create and deal with new situations by applying past experiences.  Expressed willingness to teach others and share results.  Capable of meeting time demands necessary to execute experiments.

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At Cincinnati Children’s, we come to work with one goal: to make children’s health better. We believe in a holistic team approach, both in caring for patients and their families, and in advancing science and discovery. We strive to do better and find energy and inspiration in our shared purpose. If you want to be the best you can be, you can do it at Cincinnati Children’s. 

 Cincinnati Children's is: 

• Recognized by U.S. News & World Report as a top 10  best Children's Hospitals in the nation for more than 15 years 

• Consistently among the top 3 Children's Hospitals for National Institutes of Health (NIH) Funding 

• Recognized as one of America’s Best Large Employers  (2025), America’s Best Employers for New Grads (2025) 

• One of the nation's America’s Most Innovative Companies as noted by Fortune 

• Consistently certified as great place to work 

• A Leading Disability Employer as noted by the National Organization on Disability 

• Magnet® designated for the fourth consecutive time by the American Nurses Credentialing Center (ANCC) 

 We Embrace Innovation—Together.  We believe in empowering our teams with the tools that help us work smarter and care better. That’s why we support the responsible use of artificial intelligence. By encouraging innovation, we’re creating space for new ideas, better outcomes, and a stronger future—for all of us.

Comprehensive job description provided upon request.

Cincinnati Children’s is proud to be an Equal Opportunity Employer committed to creating an environment of dignity and respect for all our employees, patients, and families. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, age, genetic information, national origin, sexual orientation, gender identity, disability or protected veteran status. EEO/Veteran/Disability