Our laboratory conducts behavioral and 2-photon laser-scanning microscopy imaging of neuronal activity in mutant mice, with a focus on models of high-risk genetic risks for schizophrenia.

Our laboratory conducts 2-photon laser-scanning microscopy imaging of neuronal activity in the auditory system of behaving mice and rats. The laboratory is equipped with Mini-2p (Thorlabs) for imaging neuronal activity in behaving animals, two 2-photon mesoscopes (Thorlabs) for imaging large cortical and subcortical areas in awake head-fixed animals, two 2-photon microscopes for single-cell electrophysiological experiments in brain slices (Chun et al, Science 2014; Blundon et. al. Science 2017; Davenport et al., Cell 2022; Bayazitov et al., Cell Reports 2024, Patton et al., Cell Reports 2024; Eom, et al, Nature Communications 2024).

Preference will be given to applicants who have received their Ph.D. degrees in neuroscience or related fields within the last 3 years and have experience in imaging in vivo. Skills in computational neuroscience and data mining using machine learning methods are a plus.

Qualifications:

• PhD in neuroscience, or related fields

• DeepLabCut or similar methods

• Demonstrated hands-on experience with 2-photon imaging techniques

• Experience analyzing time-series data, preferably from neuroimaging or behavioral studies

• Excellent communication skills and ability to work in a collaborative environment

The successful candidate will join a diverse team of researchers whose efforts are directed toward understanding behavior at the levels of neural circuits, individual neurons, synapses, and molecules. The laboratory is part of the Department of Developmental Neurobiology, which houses specialized departmental shared resources, including an integrated support structure for rodent behavior testing, brain organoids, in vivo and ex vivo cellular imaging, bioinformatics, production of genetically engineered animal models, single-cell profiling, and advanced image processing and analysis. In addition, numerous institutional shared resources and core facilities support the laboratory by providing expertise and state-of-the-art technologies.

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