Location: Barcelona - Spain (3 days working from the office and 2 days working from home).

At Alexion, AstraZeneca Rare Disease, this role offers the opportunity to shape access to transformative medicines in areas of high unmet need and make a meaningful impact for patients living with rare haematological diseases. You will operate in a highly visible, strategic position with broad cross-functional exposure, leading portfolio-level market access, pricing, and reimbursement strategy across key markets.  This role will have a particular focus on Paroxysmal Nocturnal Hemoglobinuria (PNH) and HSCT-TMA indications. This is an opportunity for an experienced market access leader to influence critical launch and lifecycle decisions, navigate complex payer environments, and play a central role in advancing our ambition within Haematology.

What you will do:

You will join a highly valued strategic team that is fundamental to realizing the potential of our life-changing medicines. Through our work, AstraZeneca ensures that appropriate access is provided to our transformative therapies.

Alexion, AstraZeneca Rare Disease’s Global Value Access and Pricing (GVAP) team is seeking a qualified Director to join a dynamic and growing team. The successful candidate will be responsible for Haematology indication, including near-term new product launches and label expansions.

As a key member of the GVAP team, you will help shape and execute global value, access, and pricing strategies for Haematology indications, with a particular focus on the PNH and HSCT-TMA indications and its lifecycle management.

This is a strategic role that requires an understanding of global healthcare and health technology assessment (HTA) systems, competitive insights, and clinical evidence. You will use this knowledge to shape market access, pricing, and reimbursement success for critical product launches and indications.

The ideal candidate will have deep expertise in global payer, HTA, and reimbursement environments, together with a strong track record of delivering market access, pricing, and reimbursement success within rare diseases and/or Haematology.

You will be responsible for:

Value

• Lead and drive the cross-functional development of a clear and differentiated value proposition for PNH and HSCT-TMA, influencing without formal authority and navigating complex organizational environments

• Collaborate with cross-functional teams to ensure that evidence-generation plans and real-world evidence (RWE) are effectively incorporated into the value proposition.  The aim is to deliver a comprehensive value proposition, reduce payer uncertainty and optimize patient access. This includes securing timely country input on evidence-generation plans in priority target countries.

• Support to the Global Marketing and Market Access (GMMA) Commercial team in advancing PNH lifecycle management (LCM) through governance milestones, with a focus on market access potential, evidence requirements,, and target product profile (TPP) requirements.

Access

• Lead the development of global market access and pricing strategies, and support implementation in close partnership with country access representatives.

• Access pricing and reimbursement (P&R) risks and opportunities for Heamatology, and develop and implement appropriate mitigation actions.

• Create and roll out strategic value, access, and pricing communication tools and materials for PNH and HSCT-TMA to support local P&R submissions and negotiations. These may include pricing frameworks, negotiation strategies, and market access toolkits aligned with the enterprise-wide launch framework.

• Lead updates to the global PNH reimbursement dossier and the overall cross-functional market access readiness plans for Haematology, in close collaboration with key countries and support functions (HEOR, Medical, and Commercial).

• Represent the GVAP perspective and strategy across various cross-functional teams, including the Global Value Sub-Team and Global Launch Team.

• Provide strategic updates, guidance and materials to local teams as required.

• Lead the monthly Haematology, Nephrology & Transplant payer working group to align global payer strategies, share the latest P&R insights, and promote best practice sharing across countries. 

• Ensure that the patient perspective is incorporated into market access strategies and recommend approaches that support the patient voice in key payer negotiations.

Pricing

• Support the development of the Haematology pricing strategy.

• Conduct payer and value assessments to identify market-specific P&R drivers and barriers.

• Develop differentiated value propositions and use the findings to inform evidence-generation plans, regulatory strategy, and development decisions.

• Partner with the GVAP Expansion Markets team to lead and co-create market-level P&R strategies and support P&R submissions and negotiations in prioritized markets.

• Review P&R cases submitted by local markets and support country teams in maintaining product value while enabling local access.

• Work closely with country access representatives and, where relevant, the International Shared Markets GVAP team.

• Provide strategic input into access and pricing assumptions to support accurate long-term plan (LTP) and mid-term plan (MTP) assumptions.

• Monitor and communicate competitor market access and pricing developments.

• Communicate effectively with GMMA senior leadership and other key stakeholders, particularly regarding Haematology launches and the PNH lifecycle management P&R strategy.

You will need to have:

• Demonstrated leadership and the ability to take initiative and consistently deliver high-quality work in the context of rare diseases evidence, where there is greater uncertainty and competiiton.

• The ability to communicate effectively and translate science into compelling payer value story benefits for Alexion leadership and other identified stakeholders, including close collaboration with local market access colleagues and the Commercial Launch Excellence function.

• Experience developing evidence-based innovative value solutions, for example through working with local payers in the EU or commercial customers in the US.

• A relevant graduate degree, such as a PhD, PharmD, Biomedical Sciences, business, or economics qualification.

• Highly specialized rare disease and/or Haematology market access experience.

• More than 6 years of relevant drug development and/or commercialization experience within the pharmaceutical/medical industry.

• Knowledge of the needs and expectations of national and regional payers, insurers, and commercial customers in our strategic markets.

• The duties of this role are generally conducted in an office environment.  As is typical of an office-based role, employees must be able, with or without accommodation, to use a computer; engage in communications via phone, video, and electronic messaging; engage in problem-solving and non-linear thought, analysis, and dialogue; collaborate with others; maintain general availability during standard business hours.

Date Posted

Closing Date

Alexion is proud to be an Equal Employment Opportunity and Affirmative Action employer. We are committed to fostering a culture of belonging where every single person can belong because of their uniqueness. The Company will not make decisions about employment, training, compensation, promotion, and other terms and conditions of employment based on race, color, religion, creed or lack thereof, sex, sexual orientation, age, ancestry, national origin, ethnicity, citizenship status, marital status, pregnancy, (including childbirth, breastfeeding, or related medical conditions), parental status (including adoption or surrogacy), military status, protected veteran status, disability, medical condition, gender identity or expression, genetic information, mental illness or other characteristics protected by law. Alexion provides reasonable accommodations to meet the needs of candidates and employees. To begin an interactive dialogue with Alexion regarding an accommodation, please contact [email protected]. Alexion participates in E-Verify.