Position Overview

The Senior Clinical Data Manager (Sr. CDM) is responsible for leading end-to-end data management activities across one or more complex clinical trials. This role ensures high-quality, reliable clinical data that meets regulatory standards and supports timely clinical development decisions. The ideal candidate is a proactive problem solver with experience in data standards, EDC systems, and cross-functional collaboration. 

Responsibilities

Study Planning & Start-Up 

• Serve as the data management lead for assigned clinical studies, providing strategic input into protocol design and data collection strategy. 

• Develop and manage Data Management Plans (DMPs), CRF/ eCRF specifications, edit check specifications, and data validation plans. 

• Lead EDC system set-up, UAT, and deployment; coordinate with external vendors and internal biometrics teams. 

Execution & Oversight 

• Oversee all data review activities, including query management, data cleaning, discrepancy resolution, and ongoing data quality monitoring. 

• Ensure adherence to CDISC/CDASH/SDTM standards where appropriate, as well as applicable regulatory requirements (ICH-GCP, FDA, EMA). 

• Track study metrics, identifying risks and implementing mitigation strategies to maintain high-quality and timely deliverables. 

• Manage interactions with CROs, central labs, imaging vendors, and other data contributors. 

Close-Out & Reporting 

• Lead database lock activities, ensuring audit readiness and complete documentation. 

• Support statistical programming and medical writing teams in delivering data for interim analyses, CSR outputs, and regulatory filings. 

• Contribute to process improvements and knowledge sharing within the data management function. 

Qualifications

• Bachelor’s degree in relevant field 

• A minimum of 5 years of Clinical Data Management experience in the biotech/pharma industry. Oncology experience is strongly preferred.  

Knowledge and Skills

• Demonstrated expertise with EDC systems (e.g., Medidata Rave, Oracle InForm, Veeva CDMS). 

• Understanding of clinical trial methodology, regulations, and data standards. 

• Experience leading data management activities for Phase I–III global clinical trials. 

• Vendor oversight experience and ability to drive cross-functional alignment. 

• Knowledge of FDA, ICH-GCP, and 21 CFR Part 11 compliance. 

• Excellent communication, documentation, and project management skills. 

Position Overview

The Senior EDC (Electronic Data Capture) Programmer (Sr. EDCP) is responsible for leading the design, development, and maintenance of clinical trial databases in an EDC system. This role will work closely with Clinical Data Management, Biostatistics, Clinical Operations, and external vendors to ensure high-quality, compliant data collection systems that support efficient trial execution. 

Responsibilities

• Lead the design, build, validation, and deployment of a study build within an EDC system. 

• Develop and maintain edit checks, custom functions, derivations, and integrations. 

• Review study protocols and provide input on CRF design and database structure. 

• Collaborate with Data Management to ensure alignment with data standards (CDISC, SDTM where applicable). 

• Perform User Acceptance Testing (UAT) and support database releases and migrations. 

• Ensure EDC systems comply with regulatory requirements (FDA, ICH-GCP, 21 CFR Part 11). 

• Troubleshoot and resolve database issues in a timely manner. 

• Oversee and/or mentor junior programmers or external vendors. 

• Contribute to SOP development and process improvements. 

• Support data integrations with external systems (IRT, ePRO, labs, etc.). 

• Maintain documentation including specifications, validation records, and audit trails. 

Qualifications

• Bachelor’s degree in relevant field. 

• A minimum of 5 years of EDC programming experience in the biotech/pharma industry. Oncology experience is preferred.  

Knowledge and Skills

• Strong hands-on experience with at least one major EDC platform (Medidata Rave preferred). 

• Solid understanding of clinical trial processes and data flow. 

• Experience with CDISC standards (SDTM, CDASH) is preferred. 

• Familiarity with regulatory requirements (ICH-GCP, 21 CFR Part 11). 

• Strong problem-solving skills and attention to detail. 

• Ability to manage multiple studies and priorities. 

Position Overview

Immunome is seeking a highly experienced and collaborative Senior Manager, Analytical Development and QC, Small Molecule to lead analytical method development, validation, and quality control activities supporting our small molecule programs from early development through regulatory submissions and commercialization.

The successful candidate will bring deep technical expertise in small molecule analytical chemistry, understanding of cGMP and ICH expectations, and proven experience operating in an outsourced development model with CDMOs and contract testing laboratories. Reporting to the Director, Analytical Development & QC, this individual will shape Immunome’s small molecule analytical development and QC strategy and advance our oncology pipeline.

Responsibilities

Strategic Leadership

• Develop and execute phase-appropriate analytical development and QC strategies for ADC linker payload components, small molecule intermediates, and drug substance, including specifications and control strategies.
• Provide technical leadership for analytical method development, qualification, validation, and lifecycle management.
• Establish and maintain analytical development plans, stability strategies, and comparability/bridging approaches to support process changes, scale-up, and technology transfers.

Program Oversight and Execution

• Manage execution of analytical testing to support in-process controls, release, stability, and characterization.
• Partner with cross-functional leaders across CMC, Process Chemistry, Manufacturing, QA, and Regulatory to ensure seamless integration of analytical deliverables within development timelines.
• Critically review and interpret analytical data to troubleshoot methods, manufacturing issues, investigate OOS/OOT results, and drive root-cause analysis and CAPA activities.
• Support review of batch records from an analytical perspective.

Vendor and Partner Management

• Manage and provide technical oversight of CDMOs, and contract testing labs to ensure high-quality, timely, and compliant method development, validation, and routine QC testing.
• Lead scope definition, issue resolution, deviations, change controls, and inspection readiness activities.

Regulatory and Documentation Support

• Author and review analytical sections of CMC documents and regulatory submissions (e.g., IND/CTA, NDA/MAA, CTD), including method descriptions, validation summaries, specifications, and stability data.
• Support responses to analytical and quality-related questions from global health authorities and internal stakeholders.
• Ensure all analytical activities comply with cGMP and relevant regulatory/compendial guidance (e.g., ICH Q2, Q3, Q6A, Q7; USP/EP/JP).

Leadership and Collaboration

• Communicate complex analytical concepts, results, and recommendations clearly and effectively to diverse audiences.
• Contribute to building Immunome’s internal analytical capabilities and best practices, including evaluation of new technologies and analytical approaches where appropriate.

Qualifications

• A minimum of a Ph.D. in Analytical Chemistry, Pharmaceutical Sciences, Chemistry, or a related field with 5+ years of industry experience; or an M.S. with 10+ years; or a B.S. with 12+ years. Experience must be in small molecule analytical development and QC within the biopharmaceutical industry.
• Demonstrated experience developing, validating, and transferring analytical methods, small molecule intermediates and drug substance in cGMP environment.
• Hands-on expertise with chromatography and related techniques (HPLC/UPLC, GC, LC-MS, Karl Fischer, spectroscopy) and impurity profiling.
• Experience managing external partners (CDMOs/contract testing laboratories) and stability programs.
• Prior oncology drug development experience preferred.
• ADC linker payload experience preferred.
• Up to 25% travel.

Knowledge and Skills

• Highly skilled in method development using chromatographic and supporting techniques (LC, GC, IC)
• Solid understanding of phase-appropriate control strategies for small molecules (specifications, impurities, stability, and comparability).
• Working knowledge of cGMP expectations and analytical-related ICH/compendial guidance (e.g., ICH Q2, Q3, Q6A, Q7; USP/EP/JP).
• Excellent communication skills — capable of clearly conveying complex data, technical concepts, and recommendations to diverse audiences.
• Exceptional organizational, analytical, and problem-solving skills.
• Ability to work effectively in a fast-paced, dynamic biotech environment and balance multiple priorities.

Position Overview 

The Senior Director, Medical Strategy & Communications will establish a strategy to support generation and communication of scientific information. This individual will drive planning and execution of publications aligned with strategic priorities. They will lead the development and training of scientific communication materials for effective medical affairs operations, oversee establishment and growth of the medical information function, and manage medical evidence generation/ISR strategies to support external research. The position will report to the SVP, Medical Affairs and will be an integral part of the leadership team. They will be empowered to make decisions and drive results, which will require deep scientific subject matter expertise, strong business acumen, effective communication, and coaching/development skills.   

Responsibilities 

• Foster partnerships with senior leaders and cross functional teams to shape data, communication and engagement strategy.  
• Drive planning and execution of publications.  
• Lead development of scientific communication materials and training.  
• Support advisory board and congress planning.  
• Contribute to the Medical, Legal, and Regulatory (MLR) process. 
• Manage medical information function.  
• Plan and operationalize medical evidence generation activities (ISRs, etc.). 

Qualifications 

• A minimum of 6 years' experience in biotech/pharmaceutical industry medical affairs required; 8+ years preferred. 
• Oncology Medical Affairs experience is required.  
• Deep expertise in medical communications and regulatory considerations. 
• Strong interpersonal skills for effective communication. 
• Up to 10% travel required. 

Knowledge and Skills 

• Demonstrated success in driving peer reviewed publications.  
• Deep expertise in the evolving landscape of publications, medical communications, and medical information.  
• Proven ability to develop new teams and deliver on compressed timelines.  
• Strong understanding of investigator sponsored research.  
• Proven ability to independently manage complex projects and communicate effectively with a wide range of internal and external stakeholders. 

Position Overview

The Associate Director / Director, Total Rewards will strengthen engagement and retention by building a competitive, scalable, and employee-centered total rewards. This role will lead the design and administration of compensation practices, benefits, leave programs, 401(k), equity planning, and rewards & recognition ensuring our offerings attract, motivate, and retain top talent while remaining compliant, cost-effective, and aligned to our culture.  

Responsibilities

Engagement and Retention 

• Develop and execute a total rewards strategy that supports talent attraction, engagement, and retention.  

• Partner with other functions of HR and business leaders to ensure rewards programs reinforce performance, internal equity, and our culture.  

• Translate company growth and workforce needs into scalable and fiscally responsible rewards programs.   

Compensation Programs 

• Lead the development, implementation, and ongoing management of compensation plans, including salary structures, incentive programs, market pricing, pay equity analysis, and compliance oversight.  

• Support equity planning (new hire grants, promotions, refresh cycles, and annual planning) in coordination with Finance, Legal, and the equity administration partner.  

• Prepare for and support the annual compensation cycle (merit, promotion, bonus planning as applicable): tools, timelines, manager guidance, calibration support, and reporting.  

• Assist Chief Financial Officer by researching trends, gathering data and preparing compensation information to be reviewed by executive team, compensation committee, and board of directors.  

Benefits Administration  

• Oversee day-to-day benefits administration including medical, dental, vision, life/AD&D, disability, FSA, and related programs.  

• Own leave administration processes (e.g., FMLA, state leaves, disability coordination), ensuring an excellent employee experience and compliant practices.  

• Manage 401(k) administration: vendor partnership, annual testing support, audits as needed, enrollment and education initiatives.  

• Lead annual benefits renewal: plan design evaluation, cost modeling, vendor negotiations, open enrollment project management, and employee communications.  

• Ensure compliance with applicable regulations (e.g., ERISA, COBRA, HIPAA, ACA) in partnership with legal/benefits vendors and internal stakeholders.  

Rewards & Recognition  

• Own and improve recognition programs that reinforce values and performance (spot awards, peer recognition, and milestone/service awards).  

• Partner with people leaders to ensure recognition is timely, inclusive, and consistently applied across teams.  

Stakeholder Partnership & Influence  

• Serve as a strategic advisor to leaders on total rewards decisions, tradeoffs, and communications.  

• Collaborate closely with HRBPs, Talent Acquisition team, Payroll, Finance, Legal, and People Operations to ensure seamless program delivery.  

• Lead vendor relationships (brokers, carriers, leave administrator, 401(k) provider, compensation survey partners, recognition platform).  

Measurement & Continuous Improvement  

• Monitor costs, utilization, participation, and employee feedback to refine offerings and improve experience.  

• Create scalable documentation, SOPs, and governance for all total rewards programs.  

Qualifications

• Bachelor’s Degree required. 

• A minimum of 8+ years of progressive experience in Total Rewards, Compensation, Benefits, or HR, including program ownership in a scaling organization. 

• Biotech/life science industry experience is strongly preferred.  

Knowledge and Skills

• Hands-on experience with benefits administration (health plans, leave administration, 401(k)) and vendor management.  

• Strong compensation experience including benchmarking roles, creating job architecture/leveling frameworks administering annual compensation cycles, and supporting sales incentive programs.   

• Demonstrated experience with equity administration platforms and stock plan basics.  

• Strong analytical skills (modeling, reporting, and presenting insights) and ability to translate data into clear recommendations.   

• Strong stakeholder influence and experience partnering cross-functionally with Finance, Legal, Payroll, and senior leaders.  

• Excellent facilitation, program design, and communication skills.  

Position Overview

The Director / Associate Director, Learning, Development & Performance Management will be responsible for determining and executing People and Culture Programs that will enhance performance, develop leadership capabilities, and ensure the organization has the capabilities and engagement to thrive as we rapidly scale our team. 

Responsibilities

Engagement, Performance & Development  

• Build an enterprise L&D strategy explicitly focused on enhanced engagement, retention, and performance.  

• Partner with people leaders and executives to continue highlighting the importance of embedding learning and development into the culture.  

Leadership Development & Manager Enablement  

• Design and deliver leadership development programs for new, experienced, and senior leaders.  

• Equip managers to engage and retain their teams through strong fundamentals: coaching, feedback, recognition, inclusive leadership, career development, and performance conversations.  

• Develop toolkits and training that make it easy for leaders to apply learning on the job.  

Performance Management Programs  

• Own and continuously improve performance management processes (goal setting, check-ins, development plans, calibration, and performance reviews).  

• Ensure managers are trained and supported to engage in growth conversations that are clear and motivating.  

• Use performance insights to identify where teams need additional support and development.  

• Create and implement competency framework for enhanced performance.  

Capability Assessment & Talent Building  

• Help leaders assess current team skill capabilities by determining strengths, talent gaps, and actions to enhance current capabilities and minimize talent gaps.   

• Build and maintain practical capability frameworks (leadership + function-specific) that connect role expectations to development actions.  

• Enable succession planning and internal mobility by identifying talent, readiness, and development pathways.  

Measurement & Continuous Improvement  

• Define success metrics tied to engagement and retention and determine actions to improve metrics.  

• Use data and feedback to evolve programs to meet the needs of a fast-growing organization.  

  Qualifications

• Bachelor’s Degree required.  

• A minimum of 8+ years of HR experience, focused on supporting and administering learning and development, including building programs at scale.  

Knowledge and Skills

• Demonstrated success driving engagement and retention through talent development (leadership programs, manager enablement, performance management).  

• Strong stakeholder influence and demonstrated successful partnership with executives and leaders to shift behaviors and build accountability.  

• Excellent facilitation, program design, and communication skills.  

• Experience in pharma/biotech/life sciences or other regulated environments preferred. 

• Experience implementing competency frameworks, 360s assessments, and learning technology preferred.  

• Experience scaling L&D in a high-growth organization preferred. 

Position Overview 

The Senior Manager / Associate Director, External Manufacturing Operations is responsible for meeting Immunome’s supply requirements by enabling and overseeing operations performed at Contract Development and Manufacturing Organizations (CDMOs). This role focuses on biologics manufacturing but will support additional modalities as needed. 

Responsibilities 

• Serve as the Supplier Relationship Manager (SRM) for specified CDMOs and primary liaison between the CDMO and Immunome.   

• Collaborate closely with Legal to support the development and negotiation of service agreements, supply contracts, and statements of work across development and commercial phases.   

• Lead one or more Virtual Management Teams (VMTs) comprising Quality, Product Supply, Technical Development, and other cross-functional stakeholders as necessary. Ensure Immunome’s project deliverables stay on track. Align priorities and key communications with the CDMO.    

• Conduct well-organized and documented project team meetings with CDMOs. Ensure CDMO progress is tracking to plan (e.g., campaign preparation, manufacturing operations, release activities, logistics, etc.). Proactively address delays to avoid impact on supply or regulatory milestones.     

• Develop a thorough understanding of Immunome’s drug product manufacturing processes. Support technical reviews of master and executed batch records, specifications, investigations, and change requests, as required.  

• Monitor CDMO performance through Key Performance Indicators (KPIs) and drive improvements aligned with Immunome’s expectations. Lead or participate in periodic Business Review Meetings.   

• Work closely with department management and finance team to provide timely progress updates. Ensure that unexpected cost variances are communicated quickly.     

• Maintain comprehensive knowledge of the CDMO’s systems, capabilities, capacities, requirements, and business practices.   

• Monitor spending against budget. Ensure CDMO invoicing is accurate and aligned with contractual terms.   

Other Responsibilities and Projects

• Assist with technology transfers as needed, change implementation, and regulatory submission reviews.   

• Support Technical Operations sourcing efforts and the qualification of new CDMOs.    

• Support risk assessment development, and implementation of manufacturing network strategies.  

• This is an individual contributor role. Depending on the business needs and organizational considerations, this role may include staff supervisory responsibly as the product portfolio and manufacturing network expand.    

Qualifications 

• Bachelor’s or advanced degree in biotechnology, biology, chemistry, chemical engineering, or related field.  

• Minimum of 10 years of biopharmaceutical industry experience, and direct responsibility overseeing third parties performing cGMP manufacturing.     

• Ability to travel (domestic and international) up to 25%, with occasional evening and/or weekend commitment.   

Knowledge and Skills 

• Strong organizational, communication, and collaboration skills.  

• Strong technical background in biotechnology/pharmaceutical manufacturing or process development.    

• Hands-on expertise in drug product process development or cGMP drug product manufacturing. Experience with highly potent products is desired.   

• Prior success in overseeing external manufacturing operations is required, either as an SRM or Subject Matter Expert (SME). Experience with both clinical and commercial manufacturing is desired.  

• Well-versed in Quality systems and experienced with deviation investigations, change controls, and corrective actions.  

• Possess strong negotiation skills and be versed in general contractual terms.   

• Comfortable with ambiguity and uncertainty; adapt swiftly with focus on delivering to the business needs as priorities change.   

Position Overview 

The Pharmacovigilance (PV) Operations Manager at Immunome is responsible for managing day-to-day global safety operations across Immunome’s clinical stage oncology programs as well as commercial product(s). This role oversees case management activities conducted by external safety vendors, supports clinical study teams on safety matters, and ensures timely and compliant safety reporting in alignment with global regulatory requirements and Immunome’s internal standards.  

As a growing biotechnology organization, Immunome requires an adaptable and highly organized PV Operations Manager who can support cross functional communication, maintain inspection ready safety systems, and drive operational excellence across all PV workflows.  

Responsibilities

Safety Case Management Oversight  

• Oversee safety case processing activities performed by Immunome’s PV vendors, including AE/SAE intake, assessment, follow up, MedDRA coding, and regulatory submissions.  

• Ensure cases are processed within required timelines and maintain compliance with FDA, EMA, ICH, CIOMS, and other applicable regulations.  

• Validate case narratives, source documentation, and sponsor queries submitted by external partners.  

Vendor & CRO Management  

• Serve as Immunome’s point of contact for PV operations with contracted partners.  

• Monitor vendor performance through periodic metrics review, and compliance dashboards.  

• Coordinate operational clarifications and ensure prompt resolution of sponsor queries.  

Compliance, Quality, & Inspection Readiness 

• Maintain continuous inspection readiness across all safety operations, ensuring complete, accurate, and audit ready documentation.  

• Support Health Authority inspections and internal/external audits, including document preparation, responses, and CAPA tracking.  

• Contribute to development, revision, and training of Immunome SOPs, work instructions, and PV governance documents.  

Safety Systems & Data Management  

• Support data quality checks, reconciliation activities, and system updates.  

• Ensure robust data governance practices, including consistency, accuracy, and timely reconciliation with clinical databases.  

Cross Functional Collaboration  

• Partner closely with Clinical Operations, Medical Monitoring, Regulatory Affairs, Quality Assurance, and Biometrics to support safety oversight across Immunome clinical programs.  

• Provide operational input into Safety Management Plans (SMPs), Safety Data Exchange Agreements (SDEA), and clinical study documents.  

• Support preparation of aggregate safety deliverables (e.g., DSURs, SUSAR listings, annual reports) through data coordination and operational QC.  

Project & Documentation Management  

• Track PV milestones for multiple clinical programs and ensure timely sponsor review of safety documents (e.g., narratives, CIOMS/MedWatch forms).  

• Oversee documentation of operational decision making, vendor communications, and safety process deviations.  

• Facilitate safety-related communication with investigators/sites as needed.  

Qualifications

• Bachelor’s or Master’s degree in Life Sciences, Pharmacy, Nursing, or related scientific field.  

• Advanced scientific or clinical degree preferred. 

• A minimum of 5+ years of experience in pharmacovigilance or drug safety, including 2+ years in safety operations leadership or vendor oversight.  

• Experience in clinical stage biotechnology or oncology programs preferred.  

• Strong background in safety databases (Argus, ArisGlobal, or equivalent) and global safety regulations.  

Knowledge and Skills

• Deep understanding of PV operations, PV workflows, case processing, MedDRA coding, and regulatory timelines.  

• Strong organizational, analytical, and vendor management skills.  

• Ability to thrive in a fastmoving biotech environment with evolving pipelines and processes.  

• Excellent communication skills with the ability to collaborate cross functionally and represent PV during internal and external meetings.  

• Commitment to patient safety and scientific integrity.  

• Strong problem solving and critical thinking. 

• Adaptability within a growing, innovative biotech environment. 

• High attention to detail and operational rigor.  

• Team-oriented and proactive communicator.  

Position Overview

The Director, Supply Operations will lead and develop Immunome’s Supply Operations function.  This role is accountable for ensuring efficient, compliant, and uninterrupted supply of clinical and commercial packaged products.  This is a highly visible role that will help shape Product Supply infrastructure, external partner networks, operational and business processes critical to Immunome’s growing pipeline and commercial success. 

Responsibilities

• Develop and oversee a high-performing team of supply operations professionals. Maintain a positive and inclusive environment where staff are motivated, empowered, and challenged.        

• Accountable for the successful planning and execution of clinical and commercial labeling and packaging operations.   

• Own business relationship with relevant external suppliers. Develop and implement metrics and KPIs to measure performance. Ensure supplier performance is routinely reviewed via formal business review meetings and periodic executive steering committee meetings.   

• Actively engage with Planning, Commercial, Clinical Development, and Regulatory to understand evolving commercial supply and clinical study plans.   

• Monitor drug inventory levels across distribution depots and trial sites, working closely with the Planning team to ensure supply plans are appropriately adjusted as needed.   

• Advise cross-functional teams on optimal supply strategy, associated timelines, and risks.  Ensure plans are communicated and integrated into program timelines.  

• Design, develop, and implement business processes and cGMP procedures encompassing but not limited to labeling and packaging operations, comparator and co-medication sourcing, returns and reconciliation.  

• Support department leadership and Finance team to develop budgets and performance targets, ensure spending is accurately tracked and variances are communicated proactively.  

• Support the development and implementation of supply management tools for use in day-to-day operations. Support the design and implementation of systems including ERP, Serialization, IRT, etc.  

• With a continuous-improvement mindset, seek opportunities to evolve processes and systems to increase compliance and efficiency.    

• Partner with Quality to ensure efficient documentation reviews pre- and post-production and support QP release requirements where required.   

• Manage Quality systems work, including training, change controls, investigations, corrective and preventive actions.   

Qualifications

• Bachelor’s or advanced degree in Supply Chain Management, Biotechnology, or related field.  

• APICS or ISM certification is preferred.    

• Minimum of 12 years of biopharmaceutical industry experience in supply chain roles, supporting both clinical and commercial product supply.  

• Minimum of 8 years of supervisory experience.  

• Position will require domestic and international travel (up to 20%) and occasional evening and/or weekend commitment.  

Knowledge and Skills

• Excellent cross-functional collaboration, communication, and influencing skills.  

• Strong business acumen, including budgeting, forecasting, and contract negotiation.  

• Demonstrated ability to lead through ambiguity and scale operations in a dynamic environment.  

• Experience with both sterile injectables and oral dosage forms is desired.  

• Strong understanding of clinical and commercial supply and distribution models and frameworks.    

• Demonstrated experience supporting commercial product launches.  

• Thorough understanding of regulations applying to supply chain activities, including cGMP, GCP, GDP, and computer systems/Part11 compliance.     

• Thorough understanding of clinical and commercial labeling and packaging requirements, planning, and execution.   

Position Overview

Immunome is seeking a highly experienced and strategic HCP Personal Promotions Marketing Lead to lead the U.S. HCP promotional strategy and drive best-in-class field/personal execution for Varegacestat. This role serves as the primary architect of the brand’s HCP clinical narrative—shaping positioning and claims strategy to enable high-quality, compliant HCP engagement. Reporting to the Marketing Brand Lead, this leader will spearhead development of HCP promotional messaging and campaigns, lead creation of field-facing resources, and partner closely with Sales, Sales Training, Medical, Market Development, Legal, Regulatory, and Commercial Operations to deliver launch readiness and sustained field adoption and execution. Success in this role requires deep commercialization expertise in oncology, strong field acumen, and an ability to operate effectively in an entrepreneurial biotech environment.

Responsibilities

HCP Promotional Strategy and Core Messaging Development

• Lead the U.S. HCP promotional strategy for Varegacestat, ensuring alignment to overall brand strategy and evolving market dynamics.
• Develop and maintain HCP positioning, core narrative, messaging architecture, and claims strategy grounded in customer insights and clinical evidence.
• Translate market research, competitive intelligence, and field feedback into clear, actionable strategic briefs that guide creative development and promotional execution.
• Define success metrics for HCP promotion (e.g., message pull-through, call effectiveness, material utilization) and drive continuous improvement based on performance insights.

Personal Marketing Tactical Development and Execution

• Lead development of the unbranded DSE plan to build pre-launch market readiness.
• Lead development of personal promotion assets and field resources to enable high-impact engagements.
• Drive end-to-end execution from concept through approval, production, and deployment—ensuring high quality, on-time delivery, and practical usability in the field.
• Partner with MLR/PRC to ensure materials are compliant, accurate, balanced, and consistent with FDA regulations, OPDP expectations, and Immunome standards.

Field Stewardship

• Lead the field advisory committee and translate learnings into improvements across messaging, materials, and execution.
• Partner with Sales and Sales Training to build launch and ongoing training that reinforces the brand story, clinical narrative, and compliant message delivery.
• Collaborate with the Market Development team to analyze and synthesize market insights and drive education effectiveness through KOL engagement and partnership.

Brand Leadership and Operational Excellence

• Collaborate with all HCP marketing channel leads to ensure HCP promotion strategy and messaging are consistently executed across marketing executions.
• Support the Brand Lead in annual brand planning, including objectives, priorities, and launch-critical milestones.
• Own HCP personal promotion budgets, timelines, and scope of work; drive disciplined project management and clear accountability across internal and external teams.

Qualifications

• Bachelor’s degree required; advanced degree (e.g., PharmD, MBA) preferred.
• A minimum of 10 years of experience in pharmaceutical, biotech, or healthcare marketing, with a strong focus on HCP marketing
• Oncology launch experience required.
• Oncology sales experience preferred.
• Proven track record translating clinical data into compelling, compliant promotional narratives, messaging frameworks, and creative direction.
• Strong understanding of MLR/PRC processes, claims substantiation, and OPDP regulations.
• Demonstrated ability to thrive in a fast-paced biotech environment.
• Ability to travel ≥30%, including occasional weekends.

Knowledge and Skills

• Deep knowledge of U.S. HCP promotion and field sales dynamics, including the realities of call execution and the drivers of field adoption.
• Ability to build clear, differentiated messaging and equip the field with tools that are clinically credible, customer-relevant, and compliant.
• Strong analytical and problem-solving skills, with the ability to leverage market research and performance data to inform decisions and optimize impact.
• Strong project management and operational execution skills; able to manage multiple workstreams and launch-critical deadlines in a fast-paced environment.
• Excellent communication, storytelling, and presentation skills—able to simplify complex clinical information for varied audiences.
• Experience managing agencies/vendors, budgets, and complex project plans with strong operational rigor and attention to detail.
• Strong cross-functional leadership skills, including the ability to influence without authority and effectively mentor and develop junior marketers.

Position Overview 

The Executive Director / Senior Director, Project Management Lead is responsible for leading and developing Immunome’s Project Management function and ensuring consistent, high-quality project management support across Research and Development programs and functional teams. This role focuses on strengthening alignment, transparency, and execution discipline across cross-functional and program teams, while establishing scalable project management standards, governance practices, and enterprise tools.  

The Executive Director / Senior Director will oversee the project management team, ensure consistent application of planning and reporting frameworks, and partner closely with functional and program leadership to drive operational cohesion across the organization. This role will also lead Immunome’s Smartsheet platform strategy to ensure standardized communication, reporting, and project visibility across programs and functions.  

This role is ideal for a seasoned project management leader who excels at building high-performing teams, driving consistency across diverse functions, and leveraging enterprise tools to enhance transparency and execution discipline. The Executive Director / Senior Director, Project Management Lead will be instrumental in ensuring Immunome’s programs and functional initiatives are supported by standardized, scalable, and aligned project management practices.  

This position reports to the Senior Vice President of Project and Program Management and plays a key role in reinforcing organizational alignment and execution excellence.  

Responsibilities 

Project Management Team Leadership  

• Lead, mentor, and develop the Project Management team, including hiring, onboarding, coaching, and performance management.  

• Establish clear role definitions, expectations, and accountability standards for project managers embedded within program and functional teams.  

• Ensure consistent training and capability development across the PM team.  

• Assess PM capacity and align resources with evolving program and functional priorities.  

• Foster a culture of rigor, transparency, and continuous improvement within the PM function.  

Cross-Functional & Program Team Alignment  

• Partner with leaders across Research, Clinical Development, CMC, Regulatory Affairs, Commercial, Finance, and other operational groups to ensure consistent planning, milestone definition, risk tracking, and reporting practices.  

• Drive alignment between program teams and functional teams to ensure shared visibility into timelines, dependencies, decision points, and resource needs.  

• Standardize integrated planning processes to reduce variability in execution across programs.  

• Ensure transparent identification and management of cross-functional risks and interdependencies.  

• Facilitate structured governance interactions and clear escalation pathways across teams.  

• Smartsheet Platform Leadership & Execution Transparency  

• Lead the strategy, governance, and optimization of Immunome’s Smartsheet platform to support project and program management needs.  

• Establish standardized templates, dashboards, and reporting frameworks to ensure consistent communication across program and functional teams.  

• Drive adoption and disciplined use of Smartsheet as the primary platform for integrated planning, milestone tracking, and status reporting.  

• Ensure data integrity, reporting consistency, and alignment of dashboards with executive governance needs.  

• Partner with functional and program leaders to continuously refine platform utilization to enhance visibility and decision-making.  

• Provide oversight for platform enhancements, integrations, and user enablement to support organizational growth.  

Standardization, Governance & PMO Support  

• Lead development and refinement of project management standards, templates, and governance practices.  

• Ensure consistent integrated development plans, status reports, and performance metrics across all supported programs.  

• Partner with PMO leadership to strengthen executive-level reporting and portfolio transparency.  

• Monitor execution trends and identify opportunities to improve alignment, communication, and operational effectiveness.  

Program & Functional Initiative Support  

• Provide direct project management leadership for high-priority or complex initiatives as needed.  

• Support cross-functional operational initiatives beyond core development programs (e.g., platform teams, alliance support, strategic initiatives, or organizational projects).  

• Expand PM support into additional functional areas as organizational complexity increases.  

• Ensure new programs and functions are integrated into standardized PM frameworks and tools.  

Qualifications 

• Advanced degree (PhD, MD, PharmD, MBA, MS) in Life Sciences, Drug Development, Business Administration, or related field preferred.  

• A minimum of 8-10+ years of experience in biotechnology or pharmaceutical development, including significant cross-functional project management experience.  

• A minimum of 3-5+ years of project management team management experience.  

• Demonstrated experience managing and developing project management professionals.  

• Strong understanding of drug discovery and development processes.  

• Experience implementing standardized project management governance frameworks and enterprise tools.  

• Proven ability to drive alignment across matrixed program and functional teams.  

• Experience leading enterprise-level Smartsheet or comparable project portfolio management platforms strongly preferred.  

• Excellent leadership, communication, and stakeholder engagement skills.  

Knowledge and Skills 

• Deep expertise in cross-functional project management within biotechnology or pharmaceutical development.  

• Strong capability in integrated planning, resource alignment, and risk management.  

• Experience building scalable PMO structures and alignment frameworks.  

• Advanced proficiency in Smartsheet, including dashboard development, reporting frameworks, and governance structures.  
• High proficiency in Microsoft Office Suite (Word, Excel, PowerPoint).  

Position Overview

Immunome is seeking an onsite Senior IT Systems and Support Technician to serve as an experienced technical lead and key contributor to enterprise systems administration, infrastructure operations, IT service management, and cybersecurity within a regulated biotech environment. 

This role blends advanced Tier 3 support with hands-on systems administration across Microsoft 365, identity and endpoint management, enterprise applications, and laboratory systems. The ideal candidate has strong experience in ITIL-based environments and hands-on expertise with ServiceNow IT Service Management (ITSM). 

This person will help ensure the reliability, security, scalability, and regulatory compliance of corporate and GxP-regulated IT systems supporting teams across the organization. 

Responsibilities

Advanced Technical Support 

• Serve as Tier 3 escalation for complex technical issues across endpoints, infrastructure, applications, and cloud environments. 
• Mentor and provide guidance to Tier 1 and Tier 2 support technicians.  
• Serve as a senior power user and operational subject matter expert for ServiceNow. 
• Ensure complete and high-quality documentation of incidents, changes, and resolutions within ServiceNow. 
• Support continuous improvement of ITSM processes aligned with ITIL best practices. 
• Develop SOPs, knowledge base articles, and technical documentation. 
• Coordinate support activities with IT Managed Service Providers (MSPs), vendors, and internal partners. 
• Participate in on-call rotation and after-hours support as required. 

Systems Administration and Enterprise Application Support

• Administer Microsoft 365 (Exchange Online, Teams, SharePoint, Cloud PC, Entra ID). 
• Serve as system administrator for business-critical enterprise applications (ERP, CRM, HRIS, EDMS).
• Provide IT support for research and development laboratory systems 
• Oversee endpoint management platforms (Intune, JAMF, NinjaOne).
• Manage Windows and macOS workstations, mobile devices (iOS and Android), and client software applications. 
• Follow formal change management processes for regulated systems. 
• Contribute to infrastructure planning and lifecycle management initiatives.

Cybersecurity and Compliance Support 

• Serve as secondary administrator for selected cybersecurity systems. 
• Assist with security incident response and risk remediation efforts in collaboration with internal leadership and external SOC/MSP partners. 
• Support Endpoint Detection and Response (EDR), patch management, and device compliance programs. 
• Help manage identity and access controls (MFA, SSO, RBAC, conditional access). 
• Maintain GxP-regulated systems in compliance with FDA 21 CFR Part 11 and data integrity requirements. 
• Partner with Finance, Legal, and Quality during regulatory audits and inspections.

Qualifications

• A minimum of 5+ years of progressive IT support and systems administration experience. 
• A minimum of 2+ years in a Tier 3 or senior technical role. 
• Experience in life science regulated industries (biotech, pharma, medical device) strongly preferred.

Preferred Certifications

• Microsoft (M365, Azure, Intune, Windows Server) 
• ITILv4 Foundation 
• ServiceNow Certified System Administrator (CSA) 
• CompTIA A+, Network+, Security+ 
• Security-related certifications (CySA+, CISSP, or equivalent) a plus 

Knowledge and Skills

• Strong hands-on experience with ServiceNow ITSM. 
• Experience supporting on-premise and cloud computing environments. 
• Strong troubleshooting, documentation, and communication skills. 

Company Overview

Immunome is a clinical-stage targeted oncology company committed to developing first-in-class and best-in-class targeted cancer therapies. We are advancing an innovative portfolio of therapeutics, drawing on leadership that previously played key roles in the design, development, and commercialization of cutting-edge therapies, including antibody-drug conjugate therapies. Our pipeline includes varegacestat, a late-clinical stage GSI; IM-1021, a clinical-stage ROR1 ADC; and IM-3050, a FAP-targeted radiotherapy that recently received IND clearance. We are also advancing a broad portfolio of early stage ADCs pursuing undisclosed solid tumor targets.

Position Overview

Immunome is seeking a strategic Patient Marketing Lead to design and deliver a best-in-class, end-to-end patient experience. Reporting to the Marketing Brand Lead, this individual will shape how patients are identified, educated, activated, and supported throughout their disease and treatment journey. Serving as the internal champion for the patient voice, the role translates complex clinical data into meaningful, patient-centric resources and drives high-impact media strategies to reach those in need. In close collaboration with HCP marketing and patient services, this leader will help ensure a seamless transition from awareness to access and ongoing support. The ideal candidate brings deep oncology expertise and a strong foundation in patient-centric marketing.

Responsibilities

Patient Strategy

• Develop and execute a comprehensive U.S. patient marketing strategy across the product lifecycle, including unbranded disease awareness and branded campaigns
• Maintain and continuously refine the patient journey by identifying new inflection points, emotional hurdles, and barriers to treatment through ongoing insights collection
• Lead patient-focused market research, in collaboration with the market insights team, to ensure all brand messaging resonates with the lived experience of patients with desmoid tumors

Resource and Digital Ecosystem Development

• Lead the creation of all patient-facing materials (i.e., patient discussion guide, patient starter kit) and partner closely with the HCP Marketing Lead to ensure patient resources are effectively utilized by the field in the clinical setting
• Design and implement an integrated digital ecosystem (e.g., branded patient websites, paid search, social, CRM, programmatic) that supports education, activation, and treatment adherence
• Establish foundational metrics/KPIs and optimize performance in real-time

Leadership and Collaboration

• Lead the internal integration of patient insights across the organization, partnering with cross-functional teams to bridge the gap between clinical data and patient experience, ensuring a seamless and unified brand journey
• Partner with patient services and market access teams to build messaging and support tools that address affordability, reimbursement, and treatment continuity
• Coordinate with the Patient Advocacy team to ensure brand strategies align with the broader goals of the desmoid tumor community

Qualifications

• Bachelor’s degree required; Advanced degree (e.g., PharmD, MBA) preferred
• Oncology launch experience required
• 7+ years of experience in pharmaceutical, biotech, or healthcare marketing, with a strong focus on patient marketing
• Proven success in digital patient marketing (web, social, SEO/SEM, CRM, and paid media strategy) and media planning and execution
• Deep understanding of the patient journey and emotional drivers of behavior in rare oncology disease populations
• Experience collaborating with patient services (patient advocacy and PSP) to develop aligned messaging and support tools
• Demonstrated ability to thrive in a fast-paced biotech environment
• Ability to travel ≥20%, including occasional weekends

Knowledge and Skills

• Ability to build clear and differentiated patient-friendly messaging to convey clinical benefit
• Strong analytical and problem-solving skills, with the ability to leverage market research and performance data to inform decisions and optimize impact
• Strong project management and operational execution skills; able to manage multiple workstreams and launch-critical deadlines in a fast-paced environment
• Excellent communication, storytelling, and presentation skills—able to simplify complex clinical information for varied audiences
• Experience managing agencies/vendors, budgets, and complex project plans with strong operational rigor and attention to detail
• Strong understanding of MLR/PRC processes, claims substantiation, and OPDP regulations
• Strong cross-functional leadership skills, including the ability to influence without authority

Position Overview

Immunome is seeking a highly organized, proactive, and detail-oriented Contracts Manager to join its legal team. This role is ideal for a legal professional who excels at managing contract lifecycles while also being able to provide broader support across corporate, transactional, and compliance functions. The ideal candidate will have experience in the biotech or pharmaceutical industries and be comfortable supporting cross-functional teams in a fast-paced, dynamic environment.

Responsibilities 

Contracts Management

• Serve as the primary administrator for the company’s contract lifecycle management (CLM) system (e.g., Ironclad), including contract intake, routing, tracking, and archiving.
• Draft, review, and coordinate the execution of standard agreements, including NDAs, consulting agreements, SOWs, CTAs, MTAs, and vendor agreements.
• Identify and assess legal and business risks and escalate as necessary. 
• Ensure all contractual activities comply with internal policies, applicable laws and regulations, and industry best practices. 
• Maintain accurate records of contract status, key terms, and renewal/termination dates.
• Collaborate with internal stakeholders (R&D, Finance, Clinical) to ensure timely and compliant contract processing, including renewal or cancellation of existing contracts.
• Assist with improving and maintaining contract templates, playbooks, and process workflows.

Qualifications

• Bachelor’s degree required. Paralegal certificate or JD, strongly preferred.
• A minimum of 5 years of contracts management experience, biotechnology or life sciences industry experience is required.

Knowledge and Skills

• Deep understanding of contract structures, terms, and risk assessment.
• Proficiency with contract lifecycle management tools (e.g., Ironclad, ContractWorks).
• Exceptional organizational and time management skills.
• Ability to manage multiple priorities and deadlines.
• Strong interpersonal, communication, and client service skills; capable of working collaboratively across departments.
• Commitment to integrity and ethical conduct and ability to protect confidential information.
• Familiarity with software tools like DocuSign, Microsoft Office Suite, and Adobe Acrobat.
• Experience supporting clinical trial or research-related contracts, preferred.

Position Overview

Immunome is seeking a highly experienced and strategic Senior Director, Global Market Access, to lead the development and execution of global market access strategies across our oncology portfolio. The individual will play a critical role in ensuring launch readiness globally, with particular emphasis on Europe, by aligning regulatory, pricing, and reimbursement pathways to support successful launch of varegacestat in countries outside of the US.

This role will also be responsible for proactively integrating payer and HTA requirements into clinical development, evidence generation, and lifecycle planning for Immunome’s pipeline assets, to enable timely patient access and reimbursement across key markets.

The successful candidate will bring deep expertise in global pricing and reimbursement, HTA engagement, and value dossier development, with a proven track record of successfully navigating HTA submissions and delivering reimbursement outcomes. This includes demonstrated experience leading market access strategy and execution for global launches, particularly across major EU markets (e.g., Germany, France, Italy, Spain, and the UK), including AMNOG processes, joint clinical assessments under the evolving EU HTA Regulation, and national pricing and negotiation frameworks.

The role requires close collaboration with Regulatory, Clinical, Commercial, and regional affiliates to ensure evidence packages, value narratives, and pricing strategies are optimized for diverse global payer environments. This position offers a highly visible leadership opportunity to shape Immunome’s access strategy from early development through launch and beyond.

Responsibilities

Strategic Leadership

• Develop and lead global market access, pricing, and reimbursement strategy across major markets for Immunome’s oncology portfolio, aligned with the target product profile (TPP) and commercial objectives.
• Build and continuously refine the global payer value proposition, value messaging, and evidence needs (clinical, economic, and patient-relevant outcomes) to support reimbursement and uptake.
• Provide strategic guidance on access risks, opportunities, and competitor dynamics; translate evolving HTA and payer expectations into actionable development and lifecycle recommendations.

Program Oversight and Execution

• Lead global access evidence planning and value dossier development, ensuring a consistent value story across regions and readiness for launch.
• Obtain early scientific advice from HTA bodies and payers across geographies (e.g., NICE, G-BA, HAS, CADTH, PBAC and other key agencies) and advocate for incorporation of feedback into clinical development and evidence generation plans.
• Partner with HEOR, Clinical Development, Biostatistics, Regulatory, Medical Affairs, and Commercial teams to drive integrated plans for endpoints, comparators, PROs, real-world evidence, and economic modeling.

Vendor and Partner Management

• Identify, qualify, and manage global market access vendors and consultants (e.g., HEOR modelers, dossier writers, policy advisors) to deliver high-quality outputs on time and within budget.
• Maintain oversight of external partners supporting payer research, advisory boards, and submission execution, ensuring adherence to Immunome’s standards and regional requirements.

Regulatory and Documentation Support

• Lead development, review, and submission of global and regional HTA dossiers (e.g., NICE, SMC, G-BA/AMNOG, HAS, AIFA, CADTH, PBAC, ICER) and manage responses to HTA questions through appraisal and negotiation.
• Drive strategy and content alignment for European joint assessments under the EU HTA framework, including participation in Joint Clinical Assessment (JCA) and Joint Scientific Consultation (JSC) activities where applicable (preferred; nice to have).
• Ensure access deliverables are consistent with the regulatory label, clinical data package, and publication strategy; collaborate with Regulatory and Medical Writing on relevant evidence summaries and modules.

Leadership and Collaboration

• Serve as the market access lead on cross-functional program and asset teams, influencing decisions from early development through launch.
• Communicate payer/HTA requirements and recommendations clearly to senior leadership and stakeholders; build alignment and accountability around access-critical activities.
• Mentor and develop team members and foster a culture of collaboration, scientific rigor, and patient-centered decision making.

Qualifications

• Advanced degree (PharmD, PhD, MD, MSc, MPH, MBA) in life sciences, health economics, public health, pharmacy, or a related field; bachelor’s degree with equivalent experience considered.
• 12+ years experience in global market access, pricing, HTA, and reimbursement within biotech/pharma, including oncology or rare disease launch experience.
• Demonstrated track record leading successful HTA submissions and achieving favorable reimbursement outcomes across multiple geographies (e.g., EU5/UK, Canada, Australia, etc.).
• Proven experience obtaining and leveraging early scientific advice from global HTA bodies and payers to shape clinical development and evidence generation strategies.
• Strong understanding of HEOR principles, cost-effectiveness and budget impact modeling, value communication, and evidence synthesis.
• Experience leading cross-functional teams (Clinical Development, HEOR, Regulatory, Medical Affairs, Commercial, Finance) and managing multiple programs in a fast-paced environment.
• Experience with EU HTA Joint Clinical Assessment (JCA) and/or Joint Scientific Consultation (JSC) processes preferred (nice to have).
• 30% travel.

Knowledge and Skills

• Deep knowledge of global pricing and reimbursement landscapes and HTA requirements (e.g., NICE, G-BA/AMNOG, HAS, AIFA, SMC, CADTH, PBAC).
• Ability to translate payer and HTA insights into actionable development strategy recommendations for endpoints, comparators, trial design, and evidence generation.
• Expertise in global value story and value dossier development, including local adaptation; strong writing and content review capabilities.
• Strong strategic thinking and program/project management skills, with the ability to prioritize across competing timelines and stakeholders.
• Excellent communication and influencing skills, including experience presenting to executive leadership and facilitating decision making.
• Proven vendor management and budgeting skills; ability to drive high-quality deliverables through external partners.
• High learning agility and comfort operating across early-stage and late-stage development in a dynamic biotech environment.
• Strong collaborative mindset and commitment to patient-centered access and compliant, ethical conduct.

Position Overview

The HCP Non-Personal & Omnichannel Marketing Lead will lead the development of an integrated non-personal promotion, media, and omnichannel plan in support of the U.S. launch of Varegacestat. This role will play a critical part in building and optimizing a seamless, data-driven HCP experience across digital and non-personal channels to drive disease awareness, education, and brand adoption. In addition, this role will champion innovation by identifying and implementing emerging digital capabilities, including the responsible use of AI, to enhance HCP engagement, personalization, content development, and marketing effectiveness. The role requires a strategic thinker with strong digital marketing expertise, launch experience, and a deep understanding of HCP engagement in the oncology marketplace.

Responsibilities

Digital Marketing & Non-Personal Promotion

• Develop and execute data-driven HCP digital campaigns, content, and modular journeys based on time to diagnosis, specialty, prescribing behavior, and real-time engagement signals to drive disease education and product adoption
• Manage marketing automation platforms and digital engagement tools to enable personalized HCP communication
• Monitor and analyze campaign performance and engagement metrics to continuously refine targeting, creative assets, and channel mix
• Partner with media agencies to develop and optimize channel strategy, media planning and activation, ensuring precise audience targeting and efficient budget allocation

Omnichannel Strategy & Execution

• Lead the development and execution of the HCP non-personal promotion and omnichannel engagement strategy
• Design customer journeys that coordinate field promotion, digital engagement, and non-personal channels to deliver a cohesive HCP experience
• Design and implement an integrated digital ecosystem (e.g., websites, search, social, CRM, programmatic media, and paid search) that supports education, activation, and sustained engagement

Innovation & AI Enablement

• Champion the adoption of AI-driven marketing capabilities, including predictive analytics, machine learning models, and automated decisioning engines to enhance targeting, personalization, and campaign performance
• Leverage AI and advanced analytics to enable next-best-action/next-best-message frameworks, dynamic content personalization, and real-time optimization of HCP engagement
• Partner with analytics and technology teams to pilot and scale new AI-enabled marketing solutions while ensuring compliance with regulatory and data governance standards

Qualifications

• Bachelor’s degree required; Advanced degree (e.g., PharmD, MBA) preferred
• 5+ years of experience in pharmaceutical, biotech, or healthcare marketing, with a strong focus on digital, NPP, and omnichannel strategy
• Oncology launch experience required
• Proven success in digital HCP marketing (web, social, SEO/SEM, CRM, and paid media strategy) and in media planning and execution
• Strong understanding of MLR/PRC processes, claims substantiation, and OPDP regulations.
• Demonstrated ability to thrive in a fast-paced biotech environment
• Ability to travel ≥20%, including occasional weekends

Knowledge and Skills

• HCP digital and NPP expertise: Deep understanding of HCP digital engagement tactics and how to integrate channels into cohesive omnichannel journeys
• Strong analytical and problem-solving skills, with the ability to leverage market research and performance data to inform decisions and optimize impact
• Strong project management and operational execution skills; able to manage multiple workstreams and launch-critical deadlines in a fast-paced environment
• Excellent communication, storytelling, and presentation skills—able to simplify complex clinical information for varied audiences
• Experience managing agencies/vendors, budgets, and complex project plans with strong operational rigor and attention to detail

Position Overview

The Associate Director/Director, Patient Services Operations will lead and own the operational design, implementation, and governance of Immunome’s first Patient Support Program (PSP) in preparation for the company’s first commercial launch. 

This leader will translate PSP strategy into operational execution, own vendor selection and performance governance, establish compliance and reporting infrastructure, and drive launch readiness to deliver a compliant, scalable program and a best-in-class patient experience. 

This role requires a hands-on builder with strong operational discipline, cross-functional leadership skills, vendor management expertise, and data fluency in a fast-moving environment. 

Responsibilities

PSP Operational Leadership 

• Translate PSP design into detailed operational requirements and implementation plans. 
• Lead RFP development, vendor evaluation, and selection with cross-functional partners. 
• Support contract negotiations including SLAs, deliverables, and performance expectations. 
• Oversee vendor onboarding and implementation of key PSP services, including enrollment/intake, benefits verification, prior authorization and appeals support, financial assistance pathways, specialty pharmacy coordination, case management/escalations, and adherence/persistence support. 
• Develop patient and HCP materials, communication scripts, and educational assets in collaboration with Marketing. 
• Develop and deploy operational training for field teams in partnership with Sales Training, Marketing, and Compliance. 

Vendor Management & Governance

• Serve as the primary operational owner for hub and related PSP vendors. 
• Establish structured operating cadence (regular ops calls, performance reviews, risk logs). 
• Define and monitor performance dashboards and SLA attainment. 
• Ensure adherence/persistence support services are integrated into vendor workflows and governance (staffing models, documentation standards, QA monitoring, SLAs, and reporting). 
• Oversee issue escalation pathways and remediation planning to ensure delivery excellence. 

Compliance, Risk & Quality 

• Build and maintain the PSP SOP library, quality assurance framework, and audit readiness documentation. 
• Partner with Legal, Compliance, Regulatory, and PV/Safety to ensure adverse event reporting, privacy, and medical/legal review processes are fully integrated. 

Data, Analytics & Patient Journey Optimization 

• Define operational reporting requirements and vendor data architecture. 
• Establish readiness indicators prior to launch and performance KPIs post-launch. 
• Map and optimize the patient journey using patient insights and operational data; define, monitor, and report PSP metrics across access and adherence/persistence (e.g., time-to-start, outreach effectiveness, and documented reasons for therapy delays or discontinuation where available) to identify friction points and drive measurable improvements in patient experience. 
• Prepare executive-level summaries and trend reporting for leadership and cross-functional partners. 

Cross-Functional Collaboration 

• Work closely with Market Access, Medical Affairs, Legal/Compliance, Regulatory, PV/Safety, Marketing, Finance, and Field functions. 
• Partner with Commercial Enablement/Distribution on channel integration requirements, ensuring alignment with channel strategy. 
• Support enterprise readiness activities and ensure alignment with commercial strategy and patient engagement priorities. 

Qualifications

• Bachelor’s degree required; Advanced degree preferred. 
• A minimum of 5 years of experience in the pharmaceutical or biotech industry.
• A minimum of 3  years’ experience in patient services operations. 
• Oncology experience required. 

Knowledge and Skills

• Demonstrated cross functional teamwork capabilities. 
• Excellent verbal and written communication skills for a wide range of audiences. 
• Strong cross-functional leadership skills and ability to influence without authority. 
• Excellent strategic and analytical thinking abilities. 
• Agile and adaptable with a growth mindset. 
• Demonstrated experience building and implementing a Patient Support Program. 

Position Overview

We are seeking an experienced and motivated Principal Purification Process Development  Scientist to support our growing ADC pipeline. This role will be responsible for the optimization of purification processes for antibody intermediates (mAbs). The preferred candidate will coordinate and/or execute purification strategies including scale-up to tox/GMP, while demonstrating expertise in practical, robust purification strategies applicable to clinical and commercial-stage manufacturing of mAbs. The ideal candidate will have experience with technology transfer, regulatory compliance, and coordination with CDMO partners at GMP manufacturing facilities. A strong working knowledge of different purification technologies is essential, as is experience with standard analytical and characterization approaches used for biologics.

Responsibilities

• Oversee Purification Process Development strategies, including Design of Experiment (DOE) and One Factor at a Time (OFAT) approaches for critical process parameters.
• Fulfill the role of a purification subject matter expert (SME) on cross-functional CMC teams to ensure alignment on program goals, deliverables, and objectives.
• Collaborate with external CDMO partners to support the Immunome pipeline from pre-clinical, through clinical and commercial stages. Occasional travel to advise and oversee development and GMP manufacturing processes will be expected.
• Prepare essential documentation (SOPs, protocols, and reports) to support tech transfers, GMP activities, and regulatory submissions for clinical development and commercialization.
• Stay current with emerging trends, innovations, and regulatory requirements for mAb purification processes, integrating necessary or potentially beneficial features into our internal company strategies and workflows.

Qualifications

• A Bachelor’s, Master’s, or Ph.D. degree in Chemistry, Chemical/Biochemical Engineering, Biotechnology, or a related field.
• A minimum of 5 years of biotech/biopharma industry experience with a Ph.D., 8 with Masters or 10 with Bachelors with a primary focus on purification process development.
• Prior experience with tech transfer, external CDMO engagement, and internal coordination with relevant functions.
• Prior knowledge of/experience working with GMP manufacturers and processes, including familiarity with regulatory submissions.
• Lead/support authoring and reviewing of relevant module 3 sections of regulatory submissions (IND, IMPD, BLA, etc).
• Familiar with laboratory operations and needs for establishing a highly functioning development lab.
• Demonstrated success in developing and optimizing purification processes for monoclonal antibodies and recombinant proteins.
• Experience in regulatory submissions, responding to information requests, and interfacing with health authorities.

Knowledge and Skills

• A strong understanding of the common purification, analytical, and characterization approaches used for mAbs, with a solid foundation in overcoming some of the challenges encountered in these workflows.
• Must be a purification subject matter expert including chromatography separations and filtration operations (depth, dead-end, virus and ultrafiltration/diafiltration).
• Expert user of AKTA chromatographic instruments (such as AKTA Avant, AKTA Ready or similar).
• Design, plan, schedule, organize, prioritize, execute, document and present complex experiments using Design of Experiment (DOE) when needed.
• The ability to manage multiple projects simultaneously while being able to prioritize and balance hands-on tasks with strategic responsibilities.
• Exceptional communication skills, with an emphasis on effective collaborations with both internal stakeholders and external partners.
• High-throughput liquid handling systems (Tecan) experience is a plus.

Position Overview

Immunome is seeking an experienced Principal Data Architect who will define the end-to-end architecture and deployment of the organization’s enterprise data warehouse and analytics platform. This role will be responsible for managing the technical scope, data strategy, data ingestion, delivery roadmap, and partnering with stakeholders on reporting and consumption needs. Phase one will focus on commercial readiness, enabling rapid integration and trusted reporting and operational analytics from key enterprise systems and external data sources. This will be the foundation for a multi-year expansion of enterprise analytics across additional functions. 

The Principal Architect will initially be a sole contributor and will lead external consultants and implementation partners while partnering closely with the IT platform team, cybersecurity, technical and business analysts, business leadership, and executives. The role will report to the Senior Director, Business Systems.

Responsibilities

Enterprise & Solution Architecture

• Define and maintain the enterprise data architecture roadmap aligned with business and technology strategy.
• Develop reference architectures, design patterns, and reusable components for data ingestion, transformation, modeling, and analytics.
• Define enterprise standards and governance.

Data Warehouse & Analytics Architecture

• Lead the design and deployment of enterprise data warehouse and analytics solutions.
• Architect systems that support analytical, operational, and regulatory workloads using both batch and real-time data patterns.
• Define and create semantic, logical, and physical data models to support scalable analytics and self-service consumption.
• Define and implement production operating practices including monitoring, alerting, data observability, performance management, cost management, access controls, and service level expectations for data availability and quality.

Master Data Management & Data Governance

• Define and support master and reference data strategies to ensure consistency of critical enterprise data.
• Embed data quality, metadata, and lineage considerations into all architectural designs.
• Partner with governance and stewardship functions to enforce data ownership, classification, and privacy controls.

AI / Advanced Analytics Enablement

• Architect data environments that are analytics- and AI-ready, supporting feature engineering, reproducibility, and trustworthy downstream consumption.
• Partner with analytics and data science teams to ensure architectural alignment with advanced analytics use cases.

Cross-Domain Collaboration

• Lead cross functional initiatives and working sessions to define priorities, clarify requirements, resolve tradeoffs, and drive timely decisions across stakeholders.
• Lead external consultants, system integrators, and vendors by defining scope, setting deliverables, reviewing work products, and ensuring solutions meet architectural standards and business outcomes.
• Prioritize and deliver foundational commercial readiness data capabilities, including reliable integration of key commercial and enterprise data sources and scalable metric definitions to support reporting and operational workflows.
• Define and evolve the data platform operating model, including support processes, documentation standards, and a scaling plan for additional capabilities, internal roles, and partner support as adoption grows.

Qualifications

• Bachelor’s degree in Computer Science, Data Engineering, Information Systems, or a related field required; advanced degrees or relevant technical certifications preferred.
• A minimum of 10+ years’ experience in data warehouse architecture, development, or design.
• Expertise in data architecture, data modeling, and analytics system design.
• Strong understanding of batch vs. real-time data patterns and distributed data processing concepts.
• Demonstrated success implementing and/or owning production data platforms as a senior individual contributor.
• Excellent communication skills with the ability to influence technical and business stakeholders.
• Experience with Snowflake or Databricks is strongly preferred

Knowledge and Skills

• Experience designing enterprise-wide data architecture standards and governance frameworks.
• Experience with ML and AI for training system models and/or mastering unstructured data – as well as other use cases.
• Experience designing data platforms that support audit readiness, privacy controls, and regulated requirements such as FDA GxP and 21 CFR Part 11, as well as supporting internal controls expectations for public company environments.
• Experience operating in dynamic, fast-growing enterprise environments.
• Strategic thinker capable of translating architecture into measurable business outcomes.
• Strong influencer who can align stakeholders across federated teams without direct authority.
• Pragmatic, collaborative, and comfortable mentoring engineers and architects across the organization.
• Able to operate effectively across multiple business units and priorities.

Position Overview

As the Global Regulatory Lead at Immunome, you will be the key decision-maker responsible for the development and execution of innovative global regulatory strategies for our therapeutic portfolio to maximize global regulatory success towards achievement of program objectives for complex and/or multiple projects. You will work collaboratively across teams to ensure compliance and alignment with corporate objectives, driving the regulatory success of our products in development and throughout their life cycle. This position will report to the Vice President, Regulatory Affairs.

Responsibilities

Regulatory Strategy Development

• Define and implement global regulatory strategies that adapt to changing regulatory and business needs.

Cross-Functional Leadership

• Communicate key developments to project teams and stakeholders, ensuring alignment and sound judgment.
• Anticipate risks and devise solutions, understanding the likelihood of technical success for proposed strategies.

Team Leadership

• Lead the Global Regulatory Team, fostering a high-performance culture through coaching and mentoring.
• Collaborate with regional regulatory leads and vendors to ensure compliance with local regulations for global submissions.

Stakeholder Communication

• Communicate effectively with internal and external partners, advocating for regulatory positions in governance and cross-functional committees.

Risk Management

• Identify regulatory risks and opportunities, developing strategies to mitigate risks and enhance success rates.

Regulatory Submission Oversight

• Ensure timely preparation and submission of regulatory submissions (e.g., INDs, BLAs, NDAs) while maintaining compliance with regional and global requirements.
• Act as the primary contact with global health authorities and lead FDA meetings.

Continuous Improvement

• Monitor industry trends and regulatory changes, adapting strategies to mitigate impacts on product development.

Qualifications

• Bachelor’s degree in a relevant scientific discipline.
• A minimum of 10 years experience in global regulatory affairs in the pharmaceutical/biotechnology industry.
• Proven success in leading regulatory submissions and obtaining approvals in major markets.
• Experience developing oncology therapeutics is strongly preferred

Knowledge and Skills

• Direct experience leading regulatory submissions, health authority meetings and interactions with in-depth knowledge of the internal operations and outlook of the FDA, EMA and other global health authorities
• Has a comprehensive and disciplined approach to regulatory risk management and compliance through deep expertise and understanding of the oncology therapeutic area 
• Highly collaborative self-starter and team player who fosters open communication and facilitates mutual understanding and cooperation between all stakeholders 
• Outstanding communication, analytical, organizational and time management skills. 
• Experience and passion to work with small teams, ability to work comfortably under pressure under evolving scenarios and tight deadlines
• Detail-minded yet flexible work style; manage multiple projects and timelines simultaneously, and rapidly change priorities based on business needs

Position Overview

We are seeking a highly motivated and experienced Clinical Scientist to join our team. The Principal/Senior, Clinical Scientist will play a critical role in the design, execution, and interpretation of multiple clinical trials for our oncology drug candidates. This individual will work closely with cross-functional teams, including clinical operations, regulatory affairs, and research and development, to ensure the successful progression of multiple clinical programs.

Responsibilities

• Oversee the execution of clinical trials and ensure scientific and regulatory rigor.
• Design and develop multiple clinical trial protocols, informed consent forms, and other study-related documents.
• Collaborate with principal investigators, key opinion leaders, and clinical trial sites to ensure robust study design and execution. Serve as Lead Clinical Scientist for multiple trials.
• Conduct activities related to data generation and validation, including CRF design and clinical data review/query resolution.
• Contribute to the preparation of clinical study reports, regulatory submissions, and publications.
• Review development of site and CRA training materials and presentation at SIV and Investigator meetings and support on Study committee (e.g., DMC) activities.
• Perform site-facing activities such as training and responding to clinical questions.
• Participate in the strategic development of clinical development plans and timelines.
• Present clinical trial data and findings to internal and external stakeholders, including scientific advisory boards and regulatory agencies.
• Mentor and develop junior team members with potential to manage direct reports.
• Travel may be required.

Qualifications

• PhD, MD, PharmD, MS, or equivalent degree in life sciences.
• A minimum of 2 years of experience in clinical science, clinical research, or equivalent; clinical development experience is required, biopharmaceutical/biotechnology industry and oncology experience preferred.
• Strong leadership, project management, and communication skills.

Knowledge and Skills

• Extensive experience in drug development process, study design, clinical operations.
• Extensive experience in clinical trial data analysis software and tools.
• Strong knowledge and skills to support program specific data review, trend identification, and data interpretation.
• Strong understanding of regulatory requirements and guidelines for clinical trials (e.g., GCP, ICH, FDA).
• Excellent analytical, organizational, and communication skills.
• Ability to work effectively in a fast-paced, collaborative environment.
• Strong problem-solving skills and attention to detail.

E/E/O

Immunome, Inc. is an equal opportunity employer. We celebrate diversity and are committed to creating an inclusive environment for all employees.

WA State Range: Principal Scientist, Clinical Science - $169,883 - $225,742

WA State Range: Senior Scientist, Clinical Science - $145,823 - $182,019

Position Overview

The Senior Director of Statistical Programming provides leadership and oversight across clinical programs within Statistical Programming function.  This position will require managing programming resources, assisting in development of Programming infrastructure and process, providing technical support and guidance for regulatory submissions while adhering to CDISC standards and submission requirements. This role requires high-level oversight of CRO partners, technology innovation, and cross-functional leadership.

Responsibilities

• Provide leadership and line management to Statistical Programming function, ensuring focus on business priorities and values.
• Provide management and oversight of statistical programming resources including FTEs, contractors and CROs involved in early-stage and late-stage studies.
• Ensure quality and timeliness of statistical analysis, reporting, and regulatory submission deliverables. Provide hands-on programming, if required, of critical ADAMs and TLFs.
• Demonstrate strong technical expertise to promote best practices related programming environments, technology and programming skillsets
• Develop and ensure conformation to Programming SOPs and Work Practice guidelines
• Maintain strategy for capability and skill development to meet current and future requirements.
• Maintain an environment to foster creativity and transparency, and a framework for continuous improvement
• Drive standardization and innovation to ensure future fitness of the organization.

Qualifications

• PhD or Master in Biostatistics, Statistics, Computer Science or a related field.
• A minimum of 15 years of experience working in the pharmaceutical, biotech, or CRO industry. A minimum of five years of leadership experience is strongly preferred.
• Significant oncology is experience is required.

Knowledge and Skills

• Track record of leading and overseeing global regulatory submissions in oncology
• Proficiency in statistical programming languages (e.g., SAS, R).
• Solid experience with reporting process, regulatory requirements, and software development life cycle.
• Strong leadership, interpersonal, and organizational skills, and ability to work within cross-functional teams
• Strong communication skills with ability to align the company on complex technical decisions.
• Proven experience in developing and leading high-performing teams.
• Demonstrated ability to multi-task, prioritize options, anticipate challenges, identify and resolve issues, and positively influence the team.
• Thrives in a collaborative team setting and is driven by a desire to deploy innovative approaches and technologies in a high-energy environment.

Position summary:  

We are seeking an accomplished Senior Director, Clinical Development to join our passionate and collaborative team and drive the advancement of our pipeline of targeted cancer therapies. In this high-impact role, you will lead clinical strategy and execution within our innovative portfolio of ADC and radioligand therapies across all stages of development. 

Key Responsibilities:  

• Lead and execute the clinical development strategy for novel oncology therapies.  

• Collaborate with internal and external stakeholders to design and implement a clinical development plan across indications.  

• Author/lead key clinical trial documents and clinical sections of regulatory filings such as pre-INDs and INDs.  

• Serve as the primary Medical Monitor for assigned programs, including overseeing internal and external teams and providing medical guidance to CRO partners and clinical sites.  

• Support safety monitoring and pharmacovigilance activities.  

• Collaborate cross-functionally with clinical operations, regulatory, project management, manufacturing, and business development to define timelines, manage risks, and ensure milestone delivery. 

• Work closely with translational sciences to integrate key biomarker and pharmacodynamic endpoints into clinical study designs 

• Establish and maintain strong relationships with PIs, KOLs and other external stakeholders.  

• Review, assess, interpret, and communicate clinical trial data to internal stakeholders and external partners. 

• Lead clinical trial data publication efforts.  

• Facilitate key meetings such as advisory boards, safety review committees, investigator meetings.  

Qualifications:  

• M.D., D.O. or equivalent. Board certification in medical oncology or hematology preferred.   

• A minimum of 2-4+ years of experience leading Clinical Development and Phase 1 – 3 oncology clinical trials in a biotech or pharmaceutical setting.   

Knowledge and Skills 

• Proven experience advancing therapeutic programs from IND-enabling studies through early and late-stage clinical development 

• Understanding of FDA and EMA regulatory requirements and successful track record in regulatory interactions 

• Demonstrated leadership and ability to effectively manage cross-functional teams 

Don't see the right job listed? Please submit your resume here and one of our recruiters will reach out directly if an appropriate job comes up. 

Please note: This is a proactive job posting, and applications are not actively monitored on a regular cadence. We strongly encourage you to monitor our Career Page for active postings and apply to roles that are a good match for your experience, skills, and interests. 

Position Overview 

The Executive Director, Investor Relations will serve as the primary point of contact for the investment community and play a critical role in shaping Immunome’s external communications strategy. Reporting to the Chief Financial Officer, this leader will be responsible for articulating the company’s strategy, progress, and value proposition to investors, analysts, and other key financial stakeholders. The role requires deep understanding of the biotechnology sector and the ability to translate complex scientific and clinical information into clear, compelling narratives that enhance Immunome’s visibility and credibility in the capital markets. 

Responsibilities 

Investor Relations 

• Execute the investor relations program in partnership with the CEO and CFO, ensuring clear, consistent, and disciplined communication with the capital markets. 

• Own day-to-day IR execution, including investor and analyst meeting coordination, targeting support, CRM management, feedback capture, and follow-up. 

• Draft all core IR materials, including investor presentations, fact sheets, FAQs, earnings scripts, Q&A documents, and conference talk tracks. 

• Serve as the primary point of contact for sell-side analysts on logistics and clarifications; proactively identify and correct misinterpretations. 

• Coordinate investor conferences, non-deal roadshows, and other capital markets engagements. 

• Track, synthesize, and report investor sentiment and market feedback to senior management and the Board. 

Corporate Communications 

• Lead execution of the corporate communications function, with direct responsibility for drafting press releases, corporate updates, pipeline and clinical announcements, and reactive statements. 

• Translate complex scientific, clinical, and regulatory information into clear, accurate, and investable external messaging. 

• Partner closely with Legal and senior management to ensure Reg FD compliance, disclosure discipline, and appropriate risk framing. 

• Manage PR and IR agencies, setting direction and maintaining a high bar for accuracy, clarity, and quality. 

• Support media engagement and spokesperson preparation; manage inbound media inquiries as needed. 

• Ensure consistency across all external-facing materials and channels. 

Cross-functional leadership 

• Serve as the central point of coordination for external messaging across Finance, Clinical, Regulatory, Legal, and Business Development. 

• Own the external communications calendar and disclosure cadence. 

• Identify communication risks early and escalate judgment calls appropriately. 

• Support special situations, including clinical data releases, financings, and issues management. 

Qualifications

• A minimum of 10 years of experience in investor relations, corporate communications, or a closely related role within biotech, biopharma, or life sciences. 

• Public company experience, including direct involvement in earnings preparation and material disclosures. 

• Demonstrated ability to independently draft high-quality press releases, investor materials, and executive-level communications. 

• Strong scientific literacy, with the ability to understand and accurately communicate clinical data and development strategy. 

• Strong financial literacy and comfort engaging with analysts, investors, and capital markets topics. 

• Experience working closely with senior executives and serving as a trusted execution partner. 

• Experience managing external agencies (IR, PR, communications). 

• Bachelor’s degree required; advanced degree a plus. 

Knowledge and Skills 

• Exceptional written and verbal communication skills, with a proven ability to translate complex scientific and financial information into clear, disciplined external messaging. 

• Deep understanding of biotech sector dynamics and public equity markets. 

• Sound judgment around disclosure, tone, timing, and risk; effective in high-stakes, fast-moving situations. 

• Strong analytical, strategic thinking, and presentation skills. 

• Ability to operate effectively in a fast-paced, high-growth environment while maintaining precision, professionalism, and confidentiality.