Position Overview

Immunome is seeking a highly experienced and strategic HCP Personal Promotions Marketing Lead to lead the U.S. HCP promotional strategy and drive best-in-class field/personal execution for Varegacestat. This role serves as the primary architect of the brand’s HCP clinical narrative—shaping positioning and claims strategy to enable high-quality, compliant HCP engagement. Reporting to the Marketing Brand Lead, this leader will spearhead development of HCP promotional messaging and campaigns, lead creation of field-facing resources, and partner closely with Sales, Sales Training, Medical, Market Development, Legal, Regulatory, and Commercial Operations to deliver launch readiness and sustained field adoption and execution. Success in this role requires deep commercialization expertise in oncology, strong field acumen, and an ability to operate effectively in an entrepreneurial biotech environment.

Responsibilities

HCP Promotional Strategy and Core Messaging Development

• Lead the U.S. HCP promotional strategy for Varegacestat, ensuring alignment to overall brand strategy and evolving market dynamics.
• Develop and maintain HCP positioning, core narrative, messaging architecture, and claims strategy grounded in customer insights and clinical evidence.
• Translate market research, competitive intelligence, and field feedback into clear, actionable strategic briefs that guide creative development and promotional execution.
• Define success metrics for HCP promotion (e.g., message pull-through, call effectiveness, material utilization) and drive continuous improvement based on performance insights.

Personal Marketing Tactical Development and Execution

• Lead development of the unbranded DSE plan to build pre-launch market readiness.
• Lead development of personal promotion assets and field resources to enable high-impact engagements.
• Drive end-to-end execution from concept through approval, production, and deployment—ensuring high quality, on-time delivery, and practical usability in the field.
• Partner with MLR/PRC to ensure materials are compliant, accurate, balanced, and consistent with FDA regulations, OPDP expectations, and Immunome standards.

Field Stewardship

• Lead the field advisory committee and translate learnings into improvements across messaging, materials, and execution.
• Partner with Sales and Sales Training to build launch and ongoing training that reinforces the brand story, clinical narrative, and compliant message delivery.
• Collaborate with the Market Development team to analyze and synthesize market insights and drive education effectiveness through KOL engagement and partnership.

Brand Leadership and Operational Excellence

• Collaborate with all HCP marketing channel leads to ensure HCP promotion strategy and messaging are consistently executed across marketing executions.
• Support the Brand Lead in annual brand planning, including objectives, priorities, and launch-critical milestones.
• Own HCP personal promotion budgets, timelines, and scope of work; drive disciplined project management and clear accountability across internal and external teams.

Qualifications

• Bachelor’s degree required; advanced degree (e.g., PharmD, MBA) preferred.
• A minimum of 10 years of experience in pharmaceutical, biotech, or healthcare marketing, with a strong focus on HCP marketing
• Oncology launch experience required.
• Oncology sales experience preferred.
• Proven track record translating clinical data into compelling, compliant promotional narratives, messaging frameworks, and creative direction.
• Strong understanding of MLR/PRC processes, claims substantiation, and OPDP regulations.
• Demonstrated ability to thrive in a fast-paced biotech environment.
• Ability to travel ≥30%, including occasional weekends.

Knowledge and Skills

• Deep knowledge of U.S. HCP promotion and field sales dynamics, including the realities of call execution and the drivers of field adoption.
• Ability to build clear, differentiated messaging and equip the field with tools that are clinically credible, customer-relevant, and compliant.
• Strong analytical and problem-solving skills, with the ability to leverage market research and performance data to inform decisions and optimize impact.
• Strong project management and operational execution skills; able to manage multiple workstreams and launch-critical deadlines in a fast-paced environment.
• Excellent communication, storytelling, and presentation skills—able to simplify complex clinical information for varied audiences.
• Experience managing agencies/vendors, budgets, and complex project plans with strong operational rigor and attention to detail.
• Strong cross-functional leadership skills, including the ability to influence without authority and effectively mentor and develop junior marketers.

Company Overview

Immunome is a clinical-stage targeted oncology company committed to developing first-in-class and best-in-class targeted cancer therapies. We are advancing an innovative portfolio of therapeutics, drawing on leadership that previously played key roles in the design, development, and commercialization of cutting-edge therapies, including antibody-drug conjugate therapies. Our pipeline includes varegacestat, a late-clinical stage GSI; IM-1021, a clinical-stage ROR1 ADC; and IM-3050, a FAP-targeted radiotherapy that recently received IND clearance. We are also advancing a broad portfolio of early stage ADCs pursuing undisclosed solid tumor targets.

Position Overview

Immunome is seeking a strategic Patient Marketing Lead to design and deliver a best-in-class, end-to-end patient experience. Reporting to the Marketing Brand Lead, this individual will shape how patients are identified, educated, activated, and supported throughout their disease and treatment journey. Serving as the internal champion for the patient voice, the role translates complex clinical data into meaningful, patient-centric resources and drives high-impact media strategies to reach those in need. In close collaboration with HCP marketing and patient services, this leader will help ensure a seamless transition from awareness to access and ongoing support. The ideal candidate brings deep oncology expertise and a strong foundation in patient-centric marketing.

Responsibilities

Patient Strategy

• Develop and execute a comprehensive U.S. patient marketing strategy across the product lifecycle, including unbranded disease awareness and branded campaigns
• Maintain and continuously refine the patient journey by identifying new inflection points, emotional hurdles, and barriers to treatment through ongoing insights collection
• Lead patient-focused market research, in collaboration with the market insights team, to ensure all brand messaging resonates with the lived experience of patients with desmoid tumors

Resource and Digital Ecosystem Development

• Lead the creation of all patient-facing materials (i.e., patient discussion guide, patient starter kit) and partner closely with the HCP Marketing Lead to ensure patient resources are effectively utilized by the field in the clinical setting
• Design and implement an integrated digital ecosystem (e.g., branded patient websites, paid search, social, CRM, programmatic) that supports education, activation, and treatment adherence
• Establish foundational metrics/KPIs and optimize performance in real-time

Leadership and Collaboration

• Lead the internal integration of patient insights across the organization, partnering with cross-functional teams to bridge the gap between clinical data and patient experience, ensuring a seamless and unified brand journey
• Partner with patient services and market access teams to build messaging and support tools that address affordability, reimbursement, and treatment continuity
• Coordinate with the Patient Advocacy team to ensure brand strategies align with the broader goals of the desmoid tumor community

Qualifications

• Bachelor’s degree required; Advanced degree (e.g., PharmD, MBA) preferred
• Oncology launch experience required
• 7+ years of experience in pharmaceutical, biotech, or healthcare marketing, with a strong focus on patient marketing
• Proven success in digital patient marketing (web, social, SEO/SEM, CRM, and paid media strategy) and media planning and execution
• Deep understanding of the patient journey and emotional drivers of behavior in rare oncology disease populations
• Experience collaborating with patient services (patient advocacy and PSP) to develop aligned messaging and support tools
• Demonstrated ability to thrive in a fast-paced biotech environment
• Ability to travel ≥20%, including occasional weekends

Knowledge and Skills

• Ability to build clear and differentiated patient-friendly messaging to convey clinical benefit
• Strong analytical and problem-solving skills, with the ability to leverage market research and performance data to inform decisions and optimize impact
• Strong project management and operational execution skills; able to manage multiple workstreams and launch-critical deadlines in a fast-paced environment
• Excellent communication, storytelling, and presentation skills—able to simplify complex clinical information for varied audiences
• Experience managing agencies/vendors, budgets, and complex project plans with strong operational rigor and attention to detail
• Strong understanding of MLR/PRC processes, claims substantiation, and OPDP regulations
• Strong cross-functional leadership skills, including the ability to influence without authority

Position Overview

Immunome is seeking a highly experienced and strategic Senior Director, Global Market Access, to lead the development and execution of global market access strategies across our oncology portfolio. The individual will play a critical role in ensuring launch readiness globally, with particular emphasis on Europe, by aligning regulatory, pricing, and reimbursement pathways to support successful launch of varegacestat in countries outside of the US.

This role will also be responsible for proactively integrating payer and HTA requirements into clinical development, evidence generation, and lifecycle planning for Immunome’s pipeline assets, to enable timely patient access and reimbursement across key markets.

The successful candidate will bring deep expertise in global pricing and reimbursement, HTA engagement, and value dossier development, with a proven track record of successfully navigating HTA submissions and delivering reimbursement outcomes. This includes demonstrated experience leading market access strategy and execution for global launches, particularly across major EU markets (e.g., Germany, France, Italy, Spain, and the UK), including AMNOG processes, joint clinical assessments under the evolving EU HTA Regulation, and national pricing and negotiation frameworks.

The role requires close collaboration with Regulatory, Clinical, Commercial, and regional affiliates to ensure evidence packages, value narratives, and pricing strategies are optimized for diverse global payer environments. This position offers a highly visible leadership opportunity to shape Immunome’s access strategy from early development through launch and beyond.

Responsibilities

Strategic Leadership

• Develop and lead global market access, pricing, and reimbursement strategy across major markets for Immunome’s oncology portfolio, aligned with the target product profile (TPP) and commercial objectives.
• Build and continuously refine the global payer value proposition, value messaging, and evidence needs (clinical, economic, and patient-relevant outcomes) to support reimbursement and uptake.
• Provide strategic guidance on access risks, opportunities, and competitor dynamics; translate evolving HTA and payer expectations into actionable development and lifecycle recommendations.

Program Oversight and Execution

• Lead global access evidence planning and value dossier development, ensuring a consistent value story across regions and readiness for launch.
• Obtain early scientific advice from HTA bodies and payers across geographies (e.g., NICE, G-BA, HAS, CADTH, PBAC and other key agencies) and advocate for incorporation of feedback into clinical development and evidence generation plans.
• Partner with HEOR, Clinical Development, Biostatistics, Regulatory, Medical Affairs, and Commercial teams to drive integrated plans for endpoints, comparators, PROs, real-world evidence, and economic modeling.

Vendor and Partner Management

• Identify, qualify, and manage global market access vendors and consultants (e.g., HEOR modelers, dossier writers, policy advisors) to deliver high-quality outputs on time and within budget.
• Maintain oversight of external partners supporting payer research, advisory boards, and submission execution, ensuring adherence to Immunome’s standards and regional requirements.

Regulatory and Documentation Support

• Lead development, review, and submission of global and regional HTA dossiers (e.g., NICE, SMC, G-BA/AMNOG, HAS, AIFA, CADTH, PBAC, ICER) and manage responses to HTA questions through appraisal and negotiation.
• Drive strategy and content alignment for European joint assessments under the EU HTA framework, including participation in Joint Clinical Assessment (JCA) and Joint Scientific Consultation (JSC) activities where applicable (preferred; nice to have).
• Ensure access deliverables are consistent with the regulatory label, clinical data package, and publication strategy; collaborate with Regulatory and Medical Writing on relevant evidence summaries and modules.

Leadership and Collaboration

• Serve as the market access lead on cross-functional program and asset teams, influencing decisions from early development through launch.
• Communicate payer/HTA requirements and recommendations clearly to senior leadership and stakeholders; build alignment and accountability around access-critical activities.
• Mentor and develop team members and foster a culture of collaboration, scientific rigor, and patient-centered decision making.

Qualifications

• Advanced degree (PharmD, PhD, MD, MSc, MPH, MBA) in life sciences, health economics, public health, pharmacy, or a related field; bachelor’s degree with equivalent experience considered.
• 12+ years experience in global market access, pricing, HTA, and reimbursement within biotech/pharma, including oncology or rare disease launch experience.
• Demonstrated track record leading successful HTA submissions and achieving favorable reimbursement outcomes across multiple geographies (e.g., EU5/UK, Canada, Australia, etc.).
• Proven experience obtaining and leveraging early scientific advice from global HTA bodies and payers to shape clinical development and evidence generation strategies.
• Strong understanding of HEOR principles, cost-effectiveness and budget impact modeling, value communication, and evidence synthesis.
• Experience leading cross-functional teams (Clinical Development, HEOR, Regulatory, Medical Affairs, Commercial, Finance) and managing multiple programs in a fast-paced environment.
• Experience with EU HTA Joint Clinical Assessment (JCA) and/or Joint Scientific Consultation (JSC) processes preferred (nice to have).
• 30% travel.

Knowledge and Skills

• Deep knowledge of global pricing and reimbursement landscapes and HTA requirements (e.g., NICE, G-BA/AMNOG, HAS, AIFA, SMC, CADTH, PBAC).
• Ability to translate payer and HTA insights into actionable development strategy recommendations for endpoints, comparators, trial design, and evidence generation.
• Expertise in global value story and value dossier development, including local adaptation; strong writing and content review capabilities.
• Strong strategic thinking and program/project management skills, with the ability to prioritize across competing timelines and stakeholders.
• Excellent communication and influencing skills, including experience presenting to executive leadership and facilitating decision making.
• Proven vendor management and budgeting skills; ability to drive high-quality deliverables through external partners.
• High learning agility and comfort operating across early-stage and late-stage development in a dynamic biotech environment.
• Strong collaborative mindset and commitment to patient-centered access and compliant, ethical conduct.

Position Overview

The HCP Non-Personal & Omnichannel Marketing Lead will lead the development of an integrated non-personal promotion, media, and omnichannel plan in support of the U.S. launch of Varegacestat. This role will play a critical part in building and optimizing a seamless, data-driven HCP experience across digital and non-personal channels to drive disease awareness, education, and brand adoption. In addition, this role will champion innovation by identifying and implementing emerging digital capabilities, including the responsible use of AI, to enhance HCP engagement, personalization, content development, and marketing effectiveness. The role requires a strategic thinker with strong digital marketing expertise, launch experience, and a deep understanding of HCP engagement in the oncology marketplace.

Responsibilities

Digital Marketing & Non-Personal Promotion

• Develop and execute data-driven HCP digital campaigns, content, and modular journeys based on time to diagnosis, specialty, prescribing behavior, and real-time engagement signals to drive disease education and product adoption
• Manage marketing automation platforms and digital engagement tools to enable personalized HCP communication
• Monitor and analyze campaign performance and engagement metrics to continuously refine targeting, creative assets, and channel mix
• Partner with media agencies to develop and optimize channel strategy, media planning and activation, ensuring precise audience targeting and efficient budget allocation

Omnichannel Strategy & Execution

• Lead the development and execution of the HCP non-personal promotion and omnichannel engagement strategy
• Design customer journeys that coordinate field promotion, digital engagement, and non-personal channels to deliver a cohesive HCP experience
• Design and implement an integrated digital ecosystem (e.g., websites, search, social, CRM, programmatic media, and paid search) that supports education, activation, and sustained engagement

Innovation & AI Enablement

• Champion the adoption of AI-driven marketing capabilities, including predictive analytics, machine learning models, and automated decisioning engines to enhance targeting, personalization, and campaign performance
• Leverage AI and advanced analytics to enable next-best-action/next-best-message frameworks, dynamic content personalization, and real-time optimization of HCP engagement
• Partner with analytics and technology teams to pilot and scale new AI-enabled marketing solutions while ensuring compliance with regulatory and data governance standards

Qualifications

• Bachelor’s degree required; Advanced degree (e.g., PharmD, MBA) preferred
• 5+ years of experience in pharmaceutical, biotech, or healthcare marketing, with a strong focus on digital, NPP, and omnichannel strategy
• Oncology launch experience required
• Proven success in digital HCP marketing (web, social, SEO/SEM, CRM, and paid media strategy) and in media planning and execution
• Strong understanding of MLR/PRC processes, claims substantiation, and OPDP regulations.
• Demonstrated ability to thrive in a fast-paced biotech environment
• Ability to travel ≥20%, including occasional weekends

Knowledge and Skills

• HCP digital and NPP expertise: Deep understanding of HCP digital engagement tactics and how to integrate channels into cohesive omnichannel journeys
• Strong analytical and problem-solving skills, with the ability to leverage market research and performance data to inform decisions and optimize impact
• Strong project management and operational execution skills; able to manage multiple workstreams and launch-critical deadlines in a fast-paced environment
• Excellent communication, storytelling, and presentation skills—able to simplify complex clinical information for varied audiences
• Experience managing agencies/vendors, budgets, and complex project plans with strong operational rigor and attention to detail

Position Overview

The Associate Director/Director, Patient Services Operations will lead and own the operational design, implementation, and governance of Immunome’s first Patient Support Program (PSP) in preparation for the company’s first commercial launch. 

This leader will translate PSP strategy into operational execution, own vendor selection and performance governance, establish compliance and reporting infrastructure, and drive launch readiness to deliver a compliant, scalable program and a best-in-class patient experience. 

This role requires a hands-on builder with strong operational discipline, cross-functional leadership skills, vendor management expertise, and data fluency in a fast-moving environment. 

Responsibilities

PSP Operational Leadership 

• Translate PSP design into detailed operational requirements and implementation plans. 
• Lead RFP development, vendor evaluation, and selection with cross-functional partners. 
• Support contract negotiations including SLAs, deliverables, and performance expectations. 
• Oversee vendor onboarding and implementation of key PSP services, including enrollment/intake, benefits verification, prior authorization and appeals support, financial assistance pathways, specialty pharmacy coordination, case management/escalations, and adherence/persistence support. 
• Develop patient and HCP materials, communication scripts, and educational assets in collaboration with Marketing. 
• Develop and deploy operational training for field teams in partnership with Sales Training, Marketing, and Compliance. 

Vendor Management & Governance

• Serve as the primary operational owner for hub and related PSP vendors. 
• Establish structured operating cadence (regular ops calls, performance reviews, risk logs). 
• Define and monitor performance dashboards and SLA attainment. 
• Ensure adherence/persistence support services are integrated into vendor workflows and governance (staffing models, documentation standards, QA monitoring, SLAs, and reporting). 
• Oversee issue escalation pathways and remediation planning to ensure delivery excellence. 

Compliance, Risk & Quality 

• Build and maintain the PSP SOP library, quality assurance framework, and audit readiness documentation. 
• Partner with Legal, Compliance, Regulatory, and PV/Safety to ensure adverse event reporting, privacy, and medical/legal review processes are fully integrated. 

Data, Analytics & Patient Journey Optimization 

• Define operational reporting requirements and vendor data architecture. 
• Establish readiness indicators prior to launch and performance KPIs post-launch. 
• Map and optimize the patient journey using patient insights and operational data; define, monitor, and report PSP metrics across access and adherence/persistence (e.g., time-to-start, outreach effectiveness, and documented reasons for therapy delays or discontinuation where available) to identify friction points and drive measurable improvements in patient experience. 
• Prepare executive-level summaries and trend reporting for leadership and cross-functional partners. 

Cross-Functional Collaboration 

• Work closely with Market Access, Medical Affairs, Legal/Compliance, Regulatory, PV/Safety, Marketing, Finance, and Field functions. 
• Partner with Commercial Enablement/Distribution on channel integration requirements, ensuring alignment with channel strategy. 
• Support enterprise readiness activities and ensure alignment with commercial strategy and patient engagement priorities. 

Qualifications

• Bachelor’s degree required; Advanced degree preferred. 
• A minimum of 5 years of experience in the pharmaceutical or biotech industry.
• A minimum of 3  years’ experience in patient services operations. 
• Oncology experience required. 

Knowledge and Skills

• Demonstrated cross functional teamwork capabilities. 
• Excellent verbal and written communication skills for a wide range of audiences. 
• Strong cross-functional leadership skills and ability to influence without authority. 
• Excellent strategic and analytical thinking abilities. 
• Agile and adaptable with a growth mindset. 
• Demonstrated experience building and implementing a Patient Support Program.