Who we are

About Stripe

Stripe is a financial infrastructure platform for businesses. Millions of companies - from the world’s largest enterprises to the most ambitious startups - use Stripe to accept payments, grow their revenue, and accelerate new business opportunities. Our mission is to increase the GDP of the internet, and we have a staggering amount of work ahead. That means you have an unprecedented opportunity to put the global economy within everyone's reach while doing the most important work of your career.

About the team

We’re looking for an experienced regulatory licensing professional to manage our Audit & Regulatory Affairs team. In this role, you will coordinate with Stripe’s Legal, Financial Crimes, Finance, Accounting, Product, and Security teams, to (i) coordinate and submit regulatory license applications; (ii) manage license renewals and licence maintenance items; (iii) manage US regulatory exams and inquiries; and (iv) oversee other aspects of the team’s day-to-day activities, with a focus on licensing and exam activities related to digital assets.

Stripe’s mission is to increase the GDP of the internet. We build the most powerful and flexible tools for running an internet business. We handle billions of dollars each year and enable millions of users around the world to scale faster and more efficiently by building their businesses on Stripe. More than 80% of American adults bought something through Stripe in the last year.

Namely, Stripe’s North America regulatory affairs program plays a critical role in ensuring Stripe effectively manages its regulatory requirements and ongoing regulatory obligations for certain licensed US and Canadian entities. The role provides an excellent opportunity for a talented candidate to deploy their cross-functional licensing and regulatory exam management skills in a fast-paced and rigorous environment, enhance their regulatory risk management expertise, learn about digital assets, carve out opportunities to grow and develop, as well as lead a team of skilled and talented professionals. The successful candidate will gain wide ranging exposure to Stripe's diverse range of business lines, senior leadership, and the governance and workings of the organization.

The ideal candidate will be a self-starter who is exceptionally organized, thorough and detail-oriented, with a background in financial services, payments, digital assets, or other regulated sectors. In this role, you will get a chance to help build, enhance, mature and evolve our regulatory licensing and exam programs and be a key cross-functional partner. Stripe is both a technology company and a financial services company, and you will need to be comfortable in both worlds.

What you’ll do

The Audit & Regulatory Management Lead will help to ensure that all of the relevant components of the regulatory affairs program for licensed US and Canadian entities remain current and compliant, oversee managing and executing US regulatory examinations, and support our Compliance Audit Strategy, with the expectation to build a team who, in due time, will manage and drive exam oversight globally.

Responsibilities

• Coordinate responses to state regulatory inquiries, filings, forms, applications, renewals, surety bonds, and anything else required for license maintenance
• Assist in managing regulatory exams and inquiries, responding to regularly exam matters and monitoring the implementation and closure of any remediation items
• Stay abreast of regulatory changes, particularly with respect to digital assets, and how they impact regulatory affairs’ licensing and exam management program activities and responsibilities
• Establish and maintain relationships with internal and external partners and business units, relevant state and local agencies, licensing consultants, and outside counsel 
• Work proactively with Legal, Finance, Financial Crimes, Affiliate Officers, Product, and other key stakeholders on managing the regulatory affairs’s licensing and examination program 
• Support any end-to-end licensing, examination and related ad hoc inquiries as required in partnership with key stakeholders 
• Engage in special projects in support of the regulatory affairs program in North America

Who you are

We're looking for someone who meets the minimum requirements to be considered for the role. If you meet these requirements, you are encouraged to apply. The preferred qualifications are a bonus, not a requirement.

Minimum requirements

• Bachelor’s degree in Finance, Political Science, Economics, or a related field 
• 10+ years experience in financial services, with significant experience in payments— familiarity with money transmitter statutes, NMLS, the BSA, and other areas of financial services, such as digital assets, lending, loan brokering and collections
• A history of professional achievement, including excellent academic credentials and success at a payments startup, financial institution, public sector organization, law enforcement agency, or top in-house legal department 
• Demonstrated familiarity with leveraging Generative AI and agentic workflows to automate preparing responses to routine questions and requests
• The ability to effectively and credibly communicate with senior executives, regulators and other stakeholders 
• Great interpersonal and critical thinking skills, good judgment, and the ability to work effectively with a wide variety of people inside and outside the company
• Robust communication skills

The role:

The Vice President of Biometrics will provide strategic and operational leadership across statistical activities as the company transitions into Phase III clinical trials. This role will be responsible for defining and executing the integrated biometrics strategy, overseeing CRO and vendor partnerships, ensuring data integrity and regulatory readiness, and serving as a key leader on the clinical development team. The ideal candidate brings deep late-stage expertise, strong cross-functional leadership, and a hands-on mindset well suited for a lean, fast-growing biotech organization.

Key responsibilities:

• Provide strategic leadership for biometrics across all clinical development programs, with primary focus on Phase III execution
• Define and implement an integrated biometrics strategy supporting clinical trial design, data quality, statistical analysis, and regulatory submissions
• Serve as a core member of the clinical leadership team, partnering closely with Clinical Operations, Data Management, Regulatory Affairs, Safety, and Medical Affairs
• Lead and oversee CROs and external vendors responsible for biostatistics statistical programming and related biometrics activities.
• Oversee development and review of key deliverables including SAPs, DMPs, CRFs, TFL shells, interim analyses, database locks, and clinical study reports
• Ensure data integrity, statistical rigor, and compliance with GCP, ICH, and global regulatory requirements
• Provide strategic input into study design, endpoint selection, sample size calculations, and adaptive or innovative trial methodologies as appropriate
• Support regulatory interactions and submissions, including briefing documents, responses to health authority questions, and advisory committee preparations
• Establish scalable biometrics processes, standards, and SOPs to support late-stage development and future pipeline growth
• Build, mentor, and lead internal biostatistics capabilities over time, as appropriate to company growth

Required experience & skills:

• Bachelor’s degree or advanced degree, ideally in biostatistics, statistics, mathematics, or a related quantitative discipline
• Minimum of 12 years of progressive experience in biostatistics within the biotechnology or pharmaceutical industry
• Significant experience leading biostatistics activities for Phase III clinical trials and regulatory submissions
• Demonstrated success managing CROs and external vendors in a late-stage development environment
• Proven track record as a strategic biometrics leader, contributing substantively to complex study designs, endpoint development, and statistical strategy across global development programs; able to provide sharp, on-your-feet thinking in real-time discussions with regulators, KOLs, and cross-functional teams, while maintaining a roll-up-your-sleeves approach to engage directly with protocols, analysis plans, and data when needed.
• Strong understanding of global regulatory expectations related to clinical data, statistical analyses, and inspection readiness
• Proven ability to operate strategically while remaining hands-on in a lean organization
• Strong written and verbal communication skills with a collaborative, team-oriented approach
• Ability to thrive in a fast-paced, dynamic environment and remain comfortable with change and ambiguity
• Flexible, proactive, and hands-on mindset with a roll-up-your-sleeves, can-do attitude

Preferred experience & skills:

• Prior experience serving as a functional or biometrics lead in regulatory interactions with FDA and ex-U.S. health authorities
• Experience in cardiovascular, rare disease, or genetically driven conditions
• Background in small or mid-sized biotech companies transitioning into late-stage development
• Experience building or scaling internal biometrics functions and infrastructure
• Familiarity with innovative trial designs and modern statistical methodologies

Base Salary Range: $300K - $375K

The Enterprise Account Executive (Healthcare & Life Sciences) will report to the Director of Enterprise GTM and own revenue growth across a portfolio of Scale AI’s most strategic healthcare and life sciences customers. This role is focused on selling complex, agentic AI solutions - autonomous workflows powered by LLMs and human-in-the-loop systems - into health systems, payers, pharma, biotech, and digital health organizations.

You will act as a strategic partner to clinical, operational, and technical leaders - helping them transform core workflows such as clinical documentation, prior authorization, revenue cycle, pharmacovigilance, clinical trials, medical affairs, and patient engagement through AI agents. This is a highly consultative, technical enterprise sales role requiring deep domain fluency, strong executive presence, and the ability to navigate regulatory, compliance, and multi-stakeholder complexity.

You will own the full customer lifecycle - from origination through close, deployment, and expansion - while quarterbacking cross-functional teams across Solutions Engineering, Product, Research, and Delivery to land and scale high-impact AI programs.

You Will:

• Own and expand relationships with leading healthcare and life sciences organizations (providers, payers, pharma, biotech), focusing on multi-year, strategic AI initiatives
• Sell agentic AI solutions by mapping Scale’s capabilities to high-impact workflows (e.g., clinical documentation, prior auth, revenue cycle, patient ops, clinical trials, drug safety, medical review)
• Build trusted relationships with executive stakeholders (CIO, CTO, CMIO, Chief Data/AI Officer, Heads of Clinical Ops, R&D, Commercial)
• Develop and execute multi-threaded account strategies that drive net-new revenue, expansion, and long-term platform adoption
• Lead complex deal cycles, including ROI modeling, business case development, and mutual close plans across new business, renewals, and expansions
• Partner closely with Solutions Engineering to design and land technically credible pilots, POVs, and production deployments
• Navigate healthcare-specific regulatory and compliance requirements (e.g., HIPAA, GxP, data governance, auditability) throughout the sales process
• Act as the voice of the customer internally - informing product roadmap, agent design, and vertical-specific solutions
• Maintain strong pipeline discipline, forecasting accuracy, and deal hygiene using Salesforce, Clari, and related tools
• Operate effectively in a fast-paced, cross-functional environment with high ownership and attention to detail

Ideally, You Will Have:

• 8–12+ years of enterprise sales experience, with significant focus on healthcare or life sciences (providers, payers, pharma, biotech, or digital health)
• Proven track record of closing and expanding large, complex, multi-million dollar deals in regulated environments
• Experience selling AI/ML, data platforms, or workflow automation technologies, with the ability to position agentic / LLM-driven solutions to both technical and non-technical stakeholders
• Strong understanding of key healthcare/life sciences workflows (e.g., clinical operations, revenue cycle, patient engagement, R&D, clinical trials, pharmacovigilance)
• Demonstrated success engaging executive stakeholders and building compelling ROI-driven business cases
• Familiarity with regulatory and compliance considerations (e.g., HIPAA, FDA/GxP, data privacy, model governance)
• Strong command of enterprise sales fundamentals, including account planning, multi-threading, and forecasting discipline
• Ability to navigate long, complex sales cycles with multiple stakeholders and competing priorities
• Excellent communication, storytelling, and executive presence
• High degree of ownership, intellectual curiosity, and a consultative, customer-first mindset

Nice to Haves:

• Experience selling agentic AI, LLM platforms, or automation solutions into healthcare or life sciences
• Background working with clinical, regulatory, or data organizations
• Familiarity with EHR systems, clinical data, or real-world evidence platforms
• Experience in high-growth or emerging technology environments

About the Role >>> Submission Content Manager, Regulatory Operations 

The Submission Content Manager plays a critical role within Regulatory Operations by preparing regulatory submission documents for final publishing and delivery to global health authorities. This position ensures that all documents meet technical, formatting, and eCTD (Electronic Common Technical Document) requirements prior to formal submission. The role partners closely with Regulatory Affairs, Medical Writing, CMC, Nonclinical, and Clinical teams to ensure high-quality, compliant, and timely regulatory submissions (e.g., INDs, NDAs, MAAs, amendments). 

The ideal candidate has strong attention to detail, experience with document management and eCTD standards, and the ability to manage multiple concurrent submission activities in a fast-paced environment. 

This role is based out of either our Cambridge, Ma or San Francisco, Ca office and may require up to 15% travel. 

Your work will primarily encompass: 

Document Preparation & Formatting 

• Prepare and format submission-ready documents, including applying PDF standards, bookmarks, hyperlinks, headers/footers, and accessibility elements
• Ensure all documents meet technical standards (e.g., PDF/A compliance, OCR/searchability, file size limits)
• Verify that tracked changes, comments, draft watermarks, and metadata are removed before pre-publishing
• Serve as a subject-matter expert for the Starting Point templates and provide training, guidance, and support to cross-functional teams on how to use these templates effectively

 Submission Assembly Support 

• Assist Regulatory Operations staff in assembling and preparing eCTD sequences for publishing
• Coordinate with submission teams to confirm final document versions and readiness for publishing
• Track and document issues, risks, and deviations, escalating as appropriate
• Work closely with Regulatory Affairs, Medical Writing, CMC, Quality, and Clinical teams to ensure submission accuracy and completeness

Quality Control & Compliance 

• Perform technical QC checks on documents prior to publishing, ensuring formatting, structure, and completeness
• Develop publishing standards and guidelines in coordination with Regulatory Operations and Medical Writing 
• Ensure all pre-publishing activities comply with company SOPs, regulatory guidelines, and eCTD specifications

Ideal Candidate Profile >>>  

A love of challenging, important work. We are a pragmatic team, driven to imagine and develop meaningful therapies for improving lives. All employees within our company play a unique and crucial role in our success, both in accomplishing our mission and building a positive company culture. As such, we are looking for someone with the right combination of knowledge, experience, and attributes for this role. 

Knowledge: 

• Bachelor’s degree is required 
• Knowledge and experience of eCTD submissions 
• Knowledge and experience with enterprise document management systems, preferably Veeva RIM 
• Knowledge and understanding of global industry standards, guidelines, and validation concepts, including eCTD format and registration tracking 
• Experience with StartingPoint eCTD templates or equivalent 

 Experience: 

• Minimum 3+ years pharmaceutical industry experience in Regulatory Affairs, Regulatory Operations or Medical Writing
• Demonstrated leadership skills while working in a fast paced and changing environment
• Experience in building and submission of NDA and life-cycle management is highly desirable

Attributes: 

• Displays strong proactive acumen and inclusive way of engagement to drive decision making, turnaround time improvement and effective ways of working 
• Influences the cross-functional team to adapt fit-for purpose solutions to meet the expected timelines 
• Ability to understand, analyze and develop recommendations from multiple complex sources such as scientific and operational perspectives  
• Excellent written and verbal communication skills 
• Excellent negotiation and organizational skills 

The base pay range for this position is expected to be $145,000 - $155,000 annually, however the base pay offered may vary depending on location, market, job related knowledge, skills and capabilities, and experience. The total compensation package for this position also includes equity, bonus, and benefits. 

#LI-CK1

The Vision

At Okta, growth is our mandate, but a secure foundation is the prerequisite. In the Public Sector, this foundation is the bedrock of national security and citizen trust. As we scale, our focus is evolving beyond the "renewal transaction" toward a holistic strategy of Strategic Retention. We aren't just renewing contracts; we are securing the identity infrastructure of the US Federal Government and State & Local (SLED) agencies.

The Role

We are looking for a high-impact sales leader and strategic architect to lead our Public Sector Renewals team. As the Director, you are the steward of Okta’s largest and most complex public-interest partnerships.

In this role, you will lead a team of high-performing, individual contributor Renewals Managers. You will act as their coach, mentor, and lead strategist, navigating the unique procurement, regulatory, and budgetary landscapes of the Public Sector. You will be responsible for turning territory-level data into actionable retention playbooks, ensuring your team acts with precision, integrity, and long-term vision.

Core Responsibilities

1. Strategic Retention & Territory Architecture

• Segment Leadership: Own the retention strategy and execution for Okta’s Public Sector business, covering both US Federal and SLED markets.
• High-Value Deal Strategy: Act as the lead executive and strategic advisor for the segment’s most complex, high-stakes agreements, including those exceeding $5M+ in ARR.
• Predictive Intelligence: Move beyond basic forecasting to develop a deep, programmatic understanding of territory health, identifying risks early and designing "Path to Green" strategies that ensure long-term account stability.
• Retention Architect: Design and implement modern renewal playbooks that account for the unique cycles of public sector procurement, ensuring that our approach is proactive rather than reactive.

2. Leadership & Team Evolution

• The Leader as Coach: Manage and mentor a team of individual contributors, assisting them in navigating high-pressure negotiations and complex customer environments.
• Cultural Architect: Foster a culture of high accountability, integrity, and relentless customer focus. You will be responsible for recruiting, hiring, and developing the next generation of Public Sector renewal talent.
• Field Advocacy: Act as the voice of the Public Sector within the broader Renewals organization, ensuring that global processes are optimized for the nuances of government customers.

3. Diplomatic Power & Cross-Functional Partnership

• Sales Alignment: Partner as a peer to Public Sector Sales Leadership to ensure a unified strategy for account growth and retention.
• Government Affairs & Compliance: Collaborate closely with Government Affairs and Legal teams to stay ahead of regulatory shifts (e.g., FedRAMP) and procurement hurdles that impact our ability to retain and grow.
• Customer Success & Product Feedback: Drive a tight feedback loop with Customer Success and Product teams, ensuring that the "ground-level" reality of our government customers informs our long-term product and service roadmap.

Qualifications

• Experience: 10+ years in Renewals, Sales, or Account Management within the SaaS industry, with a minimum of 3-5 years in a high-performing leadership role.
• Public Sector Mastery: A proven track record of navigating US Federal and SLED procurement cycles, including experience with large-scale, $5M+ license agreements.
• Strategic Translator: The ability to take complex data sets and translate them into simple, winning tactics for the field.
• Negotiation Excellence: Expert-level negotiation skills with the ability to tactfully close high-value deals with a high degree of integrity and independence.
• Diplomatic Influence: Exceptional ability to partner cross-functionally with Sales, Customer Success, Product, and Government Affairs to drive collective outcomes.

Measures of Success

• Net Retention & ARR Growth: Achieve or exceed team goals for renewal rates and total ARR stabilization within the Public Sector.
• Operational Excellence: Maintain a highly accurate and predictable forecast for the segment.
• Talent Development: High engagement and performance scores from your team of Renewals Managers.

Cross-Functional Impact: Successful implementation of new retention playbooks that bridge the gap between Sales and Renewals.

#LI-Hybrd

#P25154_3426080

As a Public Policy Advisor on the Public Policy/Government Relations team, you will support Discord’s work by building trust and finding common ground with policymakers, regulators, and other stakeholders with a focus on the U.S. States. This is a hybrid role based in our San Francisco HQ and reports to the company’s Director of Americas Public Policy.

What you will do 

• Introduce Discord to policymakers and other stakeholders including educating decision-makers on our mission, our products, and our investments in privacy and safety;
• Advocate for Discord’s position on key legislative and regulatory initiatives that will impact our users and our business
• Engage in public policy coalitions with peer companies and civil society organizations.
• Monitor and analyze policy developments in the U.S. States.
• Develop public policy materials such as position papers, talking points, presentations, consultation responses, for engagement with our partners. 
• Engage with cross-functional partners (Legal, Trust and Safety, Communications, Policy), reporting on policy developments, providing expert insights,  and gathering their input. 

What you should have

• 5+ years of experience in government, public policy advocacy, and/or government relations
• Deep insight on the policymaking process in the U.S. States
• Ability to execute a multi-year strategic advocacy and public affairs program
• Work experience on technology policy initiatives such as online safety, privacy, or content moderation
• Ability to translate complex technical information into clear, compelling narratives for non-technical audiences
• Success building trust and consensus across stakeholders with different perspectives and priorities
• Willingness to travel as necessary within the U.S.

Candidates must reside in or be willing to relocate to the San Francisco Bay Area (Alameda, Contra Costa, Marin, Napa, San Francisco, San Mateo, Santa Clara, Solano, and Sonoma counties). Relocation assistance may be available.

The US base salary range for this full-time position is $156,000 to $175,500 + equity + benefits. Our salary ranges are determined by role and level. Within the range, individual pay is determined by additional factors, including job-related skills, experience, and relevant education or training. Please note that the compensation details listed in US role postings reflect the base salary only, and do not include equity, or benefits.

Block is one company built from many blocks, all united by the same purpose of economic empowerment. The blocks that form our foundational teams — People, Finance, Counsel, Hardware, Information Security, Platform Infrastructure Engineering, and more — provide support and guidance at the corporate level. They work across business groups and around the globe, spanning time zones and disciplines to develop inclusive People policies, forecast finances, give legal counsel, safeguard systems, nurture new initiatives, and more. Every challenge creates possibilities, and we need different perspectives to see them all. Bring yours to Block.

The role This role sits at the intersection of policy and communications across Block and its brands. You will help define how Block shows up in public conversations about financial access and the future of money. You'll translate complex policy and regulatory developments into clear, credible narratives rooted in the experiences of our customers and sellers. You will help ensure Block speaks with a coherent, trusted voice across our brands Square and Cash App, as well as our broader ecosystem, especially in moments where technology and public trust converge.

You will

• Lead communications strategy across Block's policy and external affairs work to drive economic empowerment for our customers and sellers
• Partner closely with Policy, Legal, Risk, and other business teams to shape external narratives
• Ensure Block's policy positions are accurately and clearly reflected in external communications, particularly in high-visibility moments
• Advance Block's policy positions through ongoing engagement across channels, including media, digital platforms, and key industry forums
• Build and manage external engagement strategies, including media relationships, op-eds, editorial boards, as well as industry dialogues, and support broader corporate communications efforts, including high-priority company initiatives as needed
• Ensure Block's voice in policy conversations is clear, consistent, and trusted
• Translate complex regulatory issues into simple, durable narratives that resonate externally

You have

• Strategic storyteller and operator with a background in policy communications, public affairs, or issues-driven storytelling in a technology or regulated environment,
• A builder's mindset. We're actively rebuilding the tools, workflows, and playbooks of a modern communications function, and we want someone who sees friction in how work gets done and feels compelled to fix it.
• We welcome candidates from non-traditional backgrounds, with strong judgment and the ability to navigate complex, high-stakes external situations.
• Ability to translate dense policy topics into clear, human language and operate effectively across product, engineering, legal, and business teams,
• Excellent writing skills, experience engaging external stakeholders, and a proactive mindset focused on shaping narratives and building understanding, not just responding to events.

We're working to build a more inclusive economy where our customers have equal access to opportunity, and we strive to live by these same values in building our workplace. Block is an equal opportunity employer evaluating all employees and job applicants without regard to identity or any legally protected class. We will consider qualified applicants with arrest or conviction records for employment in accordance with state and local laws and “fair chance” ordinances.

We believe in being fair, and are committed to an inclusive interview experience, including providing reasonable accommodations to disabled applicants throughout the recruitment process. We encourage applicants to share any needed accommodations with their recruiter, who will treat these requests as confidentially as possible. Want to learn more about what we're doing to build a workplace that is fair and square? Check out our I+D page.

While there is no specific deadline to apply for this role, U.S. roles are typically open for an average of 55 days before being filled by a successful candidate. Please refer to the date listed at the top of this job page for when this role was first posted.

About Figure

Figure (NASDAQ: FIGR) is transforming capital markets through blockchain. We’re proving that blockchain isn’t just theory - it’s powering real products used by hundreds of thousands of consumers and institutions. 

By combining blockchain’s transparency and efficiency with AI-driven automation, we’ve reimagined how loans are originated, funded, and traded in secondary markets. From faster processing times to lower costs and reduced bias, our technology is helping borrowers, investors, and financial institutions achieve better outcomes.

Together with our 170+ partners, we’ve originated over $22 billion in home equity loans (HELOCs) on our blockchain-native platform, making Figure the largest non-bank provider of home equity financing in the U.S. Figure’s ecosystem also includes YLDS, an SEC-registered yield-bearing stablecoin that operates as a tokenized money market fund, and several other products and platforms that are reshaping consumer finance and capital markets. 

We’re proud to be recognized as one of Forbes’ Most Innovative Fintech Startups in 2025 and Fast Company’s Most Innovative Companies in Finance and Personal Finance.

About Figure

We are looking for someone who wants to innovate at the intersection of crypto and securities. If this is you, you’ll be part of a team building Figure’s marketplaces and products. Figure Markets has a global marketplace platform that supports issuing and trading of digital assets, securities, and non-securities, using blockchain. You’ll have experience in one or more of the following jurisdictions: Americas, Europe, Asia, Middle East. Our Legal team plays a central role in Figure Markets’ hyper-growth and the realization of our mission of leveraging blockchain to transform financial services. Open to both in-person and remote candidates, who will report to a Senior Counsel working out of New York.

What You’ll Do

• Provide leadership in legal affairs for markets and products, providing sound advice on federal and state securities, banking, and insurance laws and rules
• Provide day-to-day legal, business, and strategic advice to internal markets-focused teams, addressing challenges and offering solutions in the development and implementation of groundbreaking Real-World Asset digital tokens and related financial products and services
• Offer comprehensive legal guidance throughout the product life cycle, from conception through to launch, operation, and eventual sunset, aiding in both the construction and, when necessary, the dismantling of products
• Remain up-to-date on existing and changing relevant digital assets, blockchain, securities, and technology laws and regulations to ensure compliance therewith
• Develop and deliver both forward-looking and ad hoc guidance to the marketing and design teams regarding matters pertaining to the product lifecycle and other related initiatives.
• Establish or continue to build strong and positive relationships with affiliates and other ecosystem players for effective product lifecycle

What We Look For

• The ideal candidate has deep financial markets experience in the securities and cryptocurrency industry, including at least 5+ years of experience practicing as either outside counsel or in-house counsel for financial services firms (mutual fund, broker-dealer, investment advisor, OTC trading businesses, money transmitter dealing in virtual assets preferred)
• Substantial subject matter expertise in securities matters, including the Securities Act of 1933, Securities Exchange Act of 1934, Investment Advisers Act of 1940, and Investment Company Act of 1940
• Experience working as an examiner, attorney, or industry specialist at a regulatory agency (SEC,  CFTC),  a plus
• Strong negotiation skills and ability to prepare and negotiate financial agreements (e.g., prime brokerage, trading agreements, lending, and derivatives documentation)
• Deep knowledge and understanding of the compliance and regulatory requirements around financial markets and crypto assets, including the regulation of RWA digital assets and crypto transactions and platforms, and blockchain technology matters (e.g., smart contracts and digital wallets) in the provision of financial services and products
• Product counseling experience in blockchain, crypto, and securities products, including the ability to apply laws and regulations to new products and/or technologies, and the ability to review products and related functionality for compliance with applicable laws
• Interest in digital assets, blockchain technology, and the innovations brought about by decentralized applications and DeFi
• J.D. and membership with at least one state bar 
• Excellent written, oral, and interpersonal communication skills for both in-person and remote audiences
• Ability to own, organize, prioritize, and manage projects effectively

Salary

• Base Compensation Range: $166,980 - $250,470/yr
• 25% annual bonus target, paid quarterly 
• Company equity in the form of RSUs

This is the compensation range for the role in the United States. Actual compensation may vary based on a candidate’s experience, skills, location, internal equity, and evolving business needs. While most offers are generally made within the middle of the range, final compensation is determined based on the factors above.

Benefits

• Comprehensive health, vision, and dental insurance with 100% employer-paid premiums for employees and their dependents on select plans
• Company HSA, FSA, Dependent Care, 401k, and commuter benefits
• Employer-funded life and disability insurance coverage
• 11 Observed Holidays & PTO plan
• Up to 12 weeks paid family leave
• Continuing education reimbursement

Depending on your residential location certain laws might regulate the way Figure manages applicant data. California Residents, please review our California Employee and General Workforce Privacy Notice for further information. By submitting your application, you are agreeing  and acknowledging that you have read and understand the above notice.

Figure will not sponsor work visas for this position. In compliance with federal law, all persons hired will be required to verify identity and eligibility to work in the United States and to complete the required employment eligibility verification form upon hire.

#LI-RF1 #LI-Remote

What You’ll Do:

The Legal and Government Affairs team at CoreWeave is highly collaborative and partners closely with teams across the company to navigate complex legal landscapes while enabling innovation and growth. The team is pragmatic, solutions-oriented, and deeply engaged in strategic decision-making, with a strong emphasis on building trusted relationships across the organization.

About the role: 

CoreWeave is seeking an experienced Associate General Counsel to support a broad portfolio of regulatory matters across energy, international trade, and emerging AI frameworks. In this role, you will work closely with cross-functional stakeholders to translate complex regulatory requirements into actionable guidance that supports business objectives. The day-to-day includes advising on regulatory risk, supporting product and infrastructure initiatives, and responding to evolving legal requirements in a rapidly scaling environment. You will also play a key role in shaping compliance programs and helping the company stay ahead of regulatory change.

In this Role You Will:

• Provide legal advice on a wide range of regulatory matters, including energy regulation, international trade compliance, and AI governance frameworks.
• Monitor, interpret, and advise on U.S. and international laws impacting operations, including export controls, sanctions, energy market requirements, and emerging AI regulations.
• Partner with business teams (e.g., GTM, Security, IT, EHS, and operations) to assess regulatory risk and develop practical, scalable compliance strategies.
• Support product, infrastructure, and commercial initiatives by embedding regulatory guidance into business decision-making.
• Lead responses to regulatory inquiries, audits, and investigations, and manage relationships with external counsel and regulators.
• Develop and maintain internal policies, procedures, and training programs to ensure compliance with applicable laws and regulations.
• Track and assess emerging regulatory trends across energy, global trade, and AI to proactively inform business strategy.

Who You Are: 

• 7+ years of relevant legal experience, preferably with a mix of law firm and in-house experience.
• Demonstrated experience advising on energy regulation, international trade (including export controls and sanctions), and/or technology or AI regulatory frameworks.
• Experience interpreting and applying U.S. regulatory regimes (e.g., OFAC, BIS) and/or international regulatory frameworks.
• Proven experience supporting compliance programs, including drafting policies, procedures, and training materials.
• Experience leading or supporting regulatory inquiries, audits, or investigations.
• Ability to translate complex regulatory requirements into clear, actionable guidance for business stakeholders.
• Experience working cross-functionally with technical, operational, or go-to-market teams.
• Strong judgment, communication skills, and ability to operate effectively in a fast-paced environment.
• Proven ability to manage multiple priorities and work cross-functionally with diverse teams.
• J.D. from an accredited law school and active membership in at least one U.S. state bar (NY, NJ, CA, DC, or WA preferred).

Preferred: (if applicable)

• Experience advising high-growth or technology-driven companies
• Experience with data center, infrastructure, or energy procurement matters
• Familiarity with emerging AI regulatory frameworks (e.g., EU AI Act, U.S. federal and state initiatives)
• Familiarity with global regulatory bodies (e.g., EU Commission) and standards organizations
• Experience supporting global operations and cross-border regulatory or commercial matters

Wondering if you’re a good fit? We believe in investing in our people, and value candidates who can bring their own diversified experiences to our teams – even if you aren't a 100% skill or experience match. Here are a few qualities we’ve found compatible with our team. If some of this describes you, we’d love to talk. 

• You enjoy turning complex regulatory challenges into clear, actionable guidance.
• You’re curious about how AI, infrastructure, and global regulation intersect.
• You bring strong expertise in regulatory risk and compliance program development.

Why CoreWeave?

At CoreWeave, we work hard, have fun, and move fast!  We’re in an exciting stage of hyper-growth that you will not want to miss out on. We’re not afraid of a little chaos, and we’re constantly learning. Our team cares deeply about how we build our product and how we work together, which is represented through our core values: 

• Be Curious at Your Core
• Act Like an Owner
• Empower Employees
• Deliver Best-in-Class Client Experiences
• Achieve More Together

We support and encourage an entrepreneurial outlook and independent thinking. We foster an environment that encourages collaboration and enables the development of innovative solutions to complex problems. As we get set for takeoff, the organization's growth opportunities are constantly expanding. You will be surrounded by some of the best talent in the industry, who will want to learn from you, too. Come join us!  

The base salary range for this role is $161,000 to $237,000. The starting salary will be determined by job-related knowledge, skills, experience, and the market location. We strive for both market alignment and internal equity when determining compensation. In addition to base salary, our total rewards package includes a discretionary bonus, equity awards, and a comprehensive benefits program (all based on eligibility).

About the Role:

The Staff, Energy Operations is a senior, development-facing role within CoreWeave’s Data Center Development organization. This position is responsible for owning the site-level utilities path required to advance data center developments from early diligence through development readiness, construction alignment, and delivery to Operations — from dirt to blinky lights.

This role owns the end-to-end execution of site-specific utility workflows, ensuring every project has a clear, validated, and de-risked path to capacity. The role operates hands-on with all utilities, developers, and internal teams to manage utility feasibility, delivery timelines, cost assumptions, and execution risk.

You will work closely on utility execution, schedule, budget, local relationships,  government affairs, and internal grid-planning teams, which remain responsible for policy, regulatory engagement, and long-range system planning.

What You’ll Do:

Site-Level Utility  Ownership (Hard Development Gate)

• Own site-specific power feasibility and validation for all Development opportunities.
• Serve as a hard Development gate — no site advances without a confirmed, executable utilities path.
• Validate availability, delivery timelines, upgrade requirements, costs, and risk profiles.

Utility Coordination & Execution

• Act as the primary site-level technical point of contact with utility providers.
• Drive  overall utility coordination, design reviews, infrastructure planning, development budgeting to turn over execution.
• Hold utilities and external partners accountable to agreed delivery schedules and milestones.
• Support on-the-ground engagement internal and external teams  with utilities, municipalities, and local stakeholders.

Alternative Power & Acceleration Strategies

• Support alternative power structures where required to accelerate delivery or mitigate risk.
• Translate alternative power paths into a clear schedule, cost, and execution impacts for Development decision-making.

Cross-Functional Integration

• Serve as the connective tissue across Development, Operations, Finance, Legal, Gov/Tax, Sustainability, Design, and Construction.
• Ensure power costs, timelines, and risks are accurately reflected in:
• Development schedules
• TCO and financial models
• Executive-level materials supporting go / no-go decisions

Construction & Operations Alignment

• Partner closely with Construction teams during Development and execution to:
• validate construction schedules and sequencing,
• Align power delivery milestones with build and commissioning plans,
• Support a clean handoff to Day 1 Operations and early operational stabilization.

This role supports construction and operational readiness but does not own construction execution.

Reporting, Governance & Communication

• Roll up all utility-related outputs through the Principal of Development, who serves as the single point of contact by jurisdiction.
• Maintain a single source of truth for:
• all site utility status,
• delivery timelines,
• risks and mitigations across the Development pipeline.
• Prepare clear, executive-ready materials (presentations, summaries, risk readouts) for leadership review and decision-making.

Contracting & Legal Support

• Partner with Legal to support negotiation and execution of: Utility Service Agreements, Interconnection Agreements, and Easements and site-specific power rights

Development-Stage Technical Due Diligence

• Take evaluation package from power teams, translate to site-specific deliverables and schedule for all utility infrastructure post diligence.
• Pressure-test assumptions to ensure Development schedules remain executable through construction and Ops handoff.

Travel Requirements:

• Willingness and ability to travel regularly (25–40%), including:
• site visits and jurisdictional reviews,
• utility and municipal meetings,
• partner and developer coordination,
• collaboration with Design, Construction, and Operations teams.
• Comfortable serving as the on-the-ground Development representative for ALL  utilities.

Who You Are:

• 10+ years of experience in power, utilities, or energy infrastructure supporting large-scale data center, industrial, or infrastructure developments.
• Proven experience aligning utility infrastructure delivery with complex construction sequencing and master project schedules.
• Demonstrated expertise in the full project development lifecycle, including early-stage supporting internal teams feasibility assessments, due diligence, and execution planning.
• Extensive experience managing direct relationships and negotiations with U.S. utility providers, specifically regarding large-load (100MW+) interconnections across multiple jurisdictions.
• Strong understanding of utility tariffs, interconnection processes, and site-level power cost modeling.
• Advanced understanding of utility tariffs, interconnection regulatory processes, and site-level power cost modeling.

Preferred:

• Extensive experience supporting the full construction lifecycle, from project inception through commissioning and transition to operational stabilization.
• Direct experience in utility operations or a utility-facing execution role with a proven track record across national or multi-regional U.S. markets.
• Technical familiarity with complex construction schedules, procurement of long-lead electrical equipment, and practical constructability assessments.
• Demonstrated mastery of project management fundamentals, including the ability to mitigate risks and manage critical-path dependencies across multiple workstreams.
• Experience developing high-level reporting, presentations, and strategic content to facilitate data-driven decision-making for executive leadership.
• Professional exposure to Joint Venture (JV) frameworks or capital-partner development models within a real estate or infrastructure context.

Wondering if you’re a good fit? We believe in investing in our people and value candidates who can bring their diverse experiences to our teams – even if you aren't a 100% skill or experience match. Here are a few qualities we’ve found compatible with our team. If some of this describes you, we’d love to talk. 

• You love to translate complex utility and interconnection processes into executable development plans that keep projects moving.
• You’re curious about how power markets, grid constraints, regulatory shifts, and commercial structures shape site feasibility and long-term infrastructure strategy.
• You’re an expert in utility coordination, workflows, and cross-functional execution — aligning all utilities, development, construction, and finance to deliver infrastructure at scale.

Why CoreWeave?

At CoreWeave, we work hard, have fun, and move fast!  We’re in an exciting stage of hyper-growth that you will not want to miss out on. We’re not afraid of a little chaos, and we’re constantly learning. Our team cares deeply about how we build our product and how we work together, which is represented through our core values: 

• Be Curious at Your Core
• Act Like an Owner
• Empower Employees
• Deliver Best-in-Class Client Experiences
• Achieve More Together

We support and encourage an entrepreneurial outlook and independent thinking. We foster an environment that encourages collaboration and enables the development of innovative solutions to complex problems. As we get set for takeoff, the organization's growth opportunities are constantly expanding. You will be surrounded by some of the best talent in the industry, who will want to learn from you, too. Come join us! 

The base salary range for this role is $161,000 to  $215,000. The starting salary will be determined by job-related knowledge, skills, experience, and the market location. We strive for both market alignment and internal equity when determining compensation. In addition to base salary, our total rewards package includes a discretionary bonus, equity awards, and a comprehensive benefits program (all based on eligibility)

What You’ll Do: 

The Employment team, within Legal and Government Affairs (LGA), partners closely with the People team and business leaders to support CoreWeave’s global workforce by delivering practical employment law guidance and building scalable, compliant employment frameworks across the jurisdictions in which we operate. In this role, you will advise on a broad range of U.S. and international employment law issues and help operationalize employment programs, policies, and practices that support a rapidly expanding organization.

About the role:

We are seeking a dynamic Senior Counsel, Employment, who will report to the Associate General Counsel, Employment, to advise on a broad range of employment law issues affecting CoreWeave’s global workforce. You will partner closely with the People team, and collaborate frequently with other key stakeholders, including Accounting, Payroll, Tax, Corporate Development, and Securities, to address workforce issues, manage legal risk, and support consistent employment practices as CoreWeave continues to scale. 

The ideal candidate will have experience supporting employment law issues in a multi-jurisdictional environment, preferably in a high-growth, technology environment. If hired, you will help support and implement CoreWeave’s employment strategy, programs, and policies while complying with applicable law in multiple jurisdictions in which CoreWeave operates. You will also help oversee litigation strategy and dispute resolution for the company across various substantive areas.

In this role, you will:

• Provide day-to-day legal advice and support under the direction of the Associate General Counsel, Employment on a variety of U.S. and global employment law matters, including recruiting, hiring, and terminations, employment and separation documentation, EORs and PEOs, compensation and benefits, leaves of absence, reasonable accommodations, performance management, restrictive covenants, employee classifications, employment disputes, organizational restructures, and transactional-related employment matters.
• Support and help manage the company’s litigation and pre-litigation matters across substantive areas (including employment, commercial, and regulatory disputes); partner with outside counsel on case strategy, discovery, settlement, and trial preparation; and coordinate with internal stakeholders on litigation holds, document preservation, and reporting.
• Provide timely, business-focused advice and counseling in support of CoreWeave’s workforce strategies and policies, including identifying jurisdiction-specific risks and escalating issues as appropriate, in accordance with evolving laws and regulations.
• Rapidly build trusted and inclusive partnerships with our People team and provide clear insights to address concerns and reach best outcomes.
• Review, interpret, draft, and update company policies and procedures.
• Monitor legislation, regulations, case law and government enforcement activities relating to relevant employment law areas, and surface key developments, trends, and risks to relevant Legal, People, and business partners.
• Help build a robust corporate compliance program, including assisting with enhancing and maintaining employment policies, processes, and training programs with scalable frameworks.
• Conduct legal research on U.S. and international employment law issues and prepare summaries and recommendations for review by senior team members.
• Work collaboratively to prioritize business objectives and support overall company success in a fast-paced, global operating environment.
• Support the management of outside counsel—including local counsel in non-U.S. jurisdictions—by coordinating requests, reviewing work product, and escalating recommendations as appropriate.
• Support other projects, as needed.

Minimum Qualifications:

• 5+ years of relevant employment law and litigation experience, including advising on U.S. and global workforce matters.
• Required experience supporting employment matters in a multi-jurisdictional environment, including working with EORs and/or PEOs, local counsel, or regional People teams outside the U.S. 
• Demonstrated litigation experience, including managing pre-litigation disputes, agency charges, internal investigations, arbitrations, and single-plaintiff and class/collective actions, and overseeing outside counsel through discovery, settlement, and trial.
• Experience gained through a combination of law firm and/or in-house roles, preferably at a global, high-growth, tech and/or publicly-traded company.
• Strong foundational knowledge of employment law and experience applying legal principles across jurisdictions.
• Ability to independently handle routine and moderately complex employment law matters, while exercising sound judgment regarding escalation.
• Strong interpersonal skills, including the ability to communicate effectively with a wide variety of people, collaborate with diverse business groups, and build strong working relationships. 
• Ability to receive feedback and demonstrate continuous growth within the role. 
• Strong problem-solving skills to digest issues, evaluate solutions, and recommend practical approaches.
• Excellent drafting, written, verbal communication, legal interpretation, and research skills.
• A commitment to professional conduct, excellence, and meticulous attention to detail, sometimes under time pressure.
• Ability to balance legal risk mitigation against business objectives with guidance from senior leaders.
• Experience working with or coordinating outside counsel, including non-U.S. counsel, preferred.
• J.D. degree & membership in at least one state bar. 

Wondering if you’re a good fit? We believe in investing in our people, and value candidates who can bring their own diversified experiences to our teams – even if you aren't a 100% skill or experience match. Here are a few qualities we’ve found compatible with our team. If some of this describes you, we’d love to talk. 

• Practical, solution-oriented and ready to roll up your sleeves.
• Excellent communication skills and a demonstrated ability to work collaboratively in a fast-paced environment.
• You’re curious about how AI, cloud, and digital infrastructure are reshaping the global economy.

Why CoreWeave?

At CoreWeave, we work hard, have fun, and move fast!  We’re in an exciting stage of hyper-growth that you will not want to miss out on. We’re not afraid of a little chaos, and we’re constantly learning. Our team cares deeply about how we build our product and how we work together, which is represented through our core values: 

• Be Curious at Your Core
• Act Like an Owner
• Empower Employees
• Deliver Best-in-Class Client Experiences
• Achieve More Together

We support and encourage an entrepreneurial outlook and independent thinking. We foster an environment that encourages collaboration and enables the development of innovative solutions to complex problems. As we get set for takeoff, the organization's growth opportunities are constantly expanding. You will be surrounded by some of the best talent in the industry, who will want to learn from you, too. Come join us!  

The base salary range for this role is $143,000 to $210,000. The starting salary will be determined by job-related knowledge, skills, experience, and the market location. We strive for both market alignment and internal equity when determining compensation. In addition to base salary, our total rewards package includes a discretionary bonus, equity awards, and a comprehensive benefits program (all based on eligibility).

What You’ll Do:

The Deputy General Counsel, Energy, will support CoreWeave’s rapidly scaling global data center and cloud infrastructure offerings for the global market. This role will lead complex commercial power and related infrastructure transactions that enable the deployment and operation of hyperscale data centers and high-performance compute environments worldwide, while supporting CoreWeave’s growth, speed, and operational excellence. Although this position will focus on the comprehensive breadth of CoreWeave’s energy transactions, there will be an emphasis on power procurement. 

About the Role:
This position will operate as a hands-on, business-embedded legal partner, working closely with leadership and cross-functional teams to structure and execute high-impact transactions in a fast-moving, technically sophisticated environment. The role will report to the General Counsel.

In this role, you will:

• Serve as a trusted legal advisor to C-Level and senior management on power strategy and transactions and solutions critical to CoreWeave’s global data center, infrastructure, and service offering growth. Advise on energy and power procurement for the company’s growing portfolio of data centers, sourcing of all energy resources, and contracting strategies with counterparties to support high-density compute workloads and data center operations.
• Lead and negotiate complex power agreements and programs supporting CoreWeave’s cloud and data center operations, including power purchase agreements (PPAs), LOI’s, build-to-transfer, renewable energy and other power generation sources, utility service, colocation, interconnection, and other energy infrastructure and development-related contracts and transactions involving the environmental attributes of clean power sources.
• Negotiate directly with utilities, energy providers, data center operators, contractors, suppliers, and strategic partners across domestic and international geographic markets.
• Partner closely with internal cross-functional working groups across strategic financing, commercial, data center operations, government affairs, sustainability, real estate, and finance teams to drive strategic infrastructure, energy, and capacity initiatives. Help execute long-term, scalable, cost-effective solutions.
• Support corporate development and project financing transactions, and help to coordinate legal aspects of energy and power procurement, infrastructure development, global data center construction, and ongoing operations.
• Provide counsel and support to Government Affairs and other affected teams to understand existing and proposed Public Utility Commission (PUC), Federal Energy Regulatory Commission (FERC), Department of Energy (DOE), and, as applicable, international government and agency rules affecting the power sector and data center infrastructure development, and their impact.
• Lead the effort in developing and coordinating responses to proposed state, local, federal, and international market energy and power rules impacting the company and its global data center operations. 
• Identify and participate in the development of a strategy to mitigate legal, regulatory, and commercial risks to power availability, global data center expansion, and operational continuity.
• Manage outside counsel, other outside experts, and budgets for specialized energy, infrastructure, and regulatory matters.

Who You Are:

• Juris Doctor (JD) from an accredited law school; active bar admission in at least one U.S. jurisdiction.
• 15+ years of experience at a law firm and/or in-house legal department, with significant experience supporting complex cloud infrastructure, data centers, energy and power procurement, and large-scale commercial energy transactions.
• Expertise in negotiating power purchase agreements and other commercial energy and power transactions.
• Expertise in and knowledge of State and Federal statutes affecting the power sector, including the Federal Power Act, Public Utility Regulatory Policies Act and the Public Utility Holding Company Act.   
• Knowledge of PUC and FERC rules impacting the power sector and administrative procedures.
• Knowledge of Independent System Operators and Regional Transmission Groups, including energy and capacity market participation and power markets.
• Knowledge of transmission, including interconnection and transmission service agreements.  
• Experience with power and energy transactions and regulatory frameworks in international markets (e.g., EMEA, APAC, LatAm, Canada) is a huge plus.
• Strong background in energy, renewables, electric infrastructure development, and utility regulation, and their relationship with hyperscale cloud and data center infrastructure operations, expansion, and global growth;
• Experience with emerging technologies such as advanced nuclear and geothermal, and with legislation and regulatory matters affecting such technologies, is a plus.

Wondering if you’re a good fit? We believe in investing in our people, and value candidates who can bring their own diversified experiences to our teams – even if you aren't a 100% skill or experience match. Here are a few qualities we’ve found compatible with our team. If some of this describes you, we’d love to talk. 

• Practical, solution-oriented and ready to roll up your sleeves.
• Excellent communication skills and a demonstrated ability to work collaboratively in a fast-paced environment.
• You’re curious about how AI, cloud, and digital infrastructure are reshaping the global economy.

Why CoreWeave?

At CoreWeave, we work hard, have fun, and move fast!  We’re in an exciting stage of hyper-growth that you will not want to miss out on. We’re not afraid of a little chaos, and we’re constantly learning. Our team cares deeply about how we build our product and how we work together, which is represented through our core values: 

• Be Curious at Your Core
• Act Like an Owner
• Empower Employees
• Deliver Best-in-Class Client Experiences
• Achieve More Together

We support and encourage an entrepreneurial outlook and independent thinking. We foster an environment that encourages collaboration and provides the opportunity to develop innovative solutions to complex problems. As we get set for takeoff, the growth opportunities within the organization are constantly expanding. You will be surrounded by some of the best talent in the industry, who will want to learn from you, too. Come join us! 

The base salary range for this role is $275,000 to $330,000. The starting salary will be determined based on job-related knowledge, skills, experience, and market location. We strive for both market alignment and internal equity when determining compensation. In addition to base salary, our total rewards package includes a discretionary bonus, equity awards, and a comprehensive benefits program (all based on eligibility).

Who We Are:

Calico (Calico Life Sciences LLC) is an Alphabet-founded research and development company whose mission is to harness advanced technologies and model systems to increase our understanding of the biology that controls human aging. Calico will use that knowledge to devise interventions that enable people to lead longer and healthier lives. Calico’s highly innovative technology labs, its commitment to curiosity-driven discovery science and, with academic and industry partners, its vibrant drug-development pipeline, together create an inspiring and exciting place to catalyze and enable medical breakthroughs.

Position Description:

The Associate Director, Clinical Scientist at Calico is responsible for the planning and execution of the translational and clinical development plans and protocols for several projects across therapeutic areas, related to Calico’s mission to improve human healthspan by understanding aging and age-related diseases. The successful candidate will participate in and drive the development of clinical strategies for assigned program(s)/indication(s) and should be able to support novel and innovative clinical plans while ensuring a positive and collaborative team environment.

Responsibilities:

• In coordination with the Head of Clinical Science and/or Medical Director(s), leads or represents the Clinical Science function in cross-functional project and study teams that develop and execute the clinical development plan to translate preclinical mechanistic data to humans for novel aging-related targets
• Authors clinical sections of assigned protocols from Phase 0 through Phase 2, collaborating with other functions required for protocol development, including Research, Biomarkers, Clinical Operations, Regulatory Affairs, Clinical Pharmacology, Biometrics, Pharmacovigilance, Toxicology, and Medical Writing
• Contributes to the design and execution of experimental medicine studies to demonstrate proof-of-mechanism of novel targets in aging and age-related diseases
• Interfaces with academic investigators to assist in execution of Investigator initiated trials
• Contributes to and/or reviews relevant study documents including Investigational Brochures, Clinical Study Reports, Statistical Analysis Plans, Operations/Technical Manuals, IND/CTAs, case report forms and data tables, listings and figures, CSRs
• Trains CROs and study site personnel on assigned protocols and addresses protocol queries as they arise
• Participates in the assessment of CROs and study vendors

Position Requirements:

•  BS/MS in a relevant scientific discipline with 8+ years or PhD/PharmD with 5+ years of experience in early clinical drug development in the biotech/pharmaceutical industry performing the responsibilities described above
• Experience in early clinical trial methodology (Phase 0, Phase 1, Phase 2) and knowledge of drug development process and clinical deliverables from IND through clinical proof-of-concept
• Excellent understanding of clinically relevant ICH GCP guidance, FDA and EMA regulations
• Ability to perform role responsibilities largely independently
• Proven leadership skills and ability to bring out the best in others on a cross-functional team
• Able to provide effective leadership through influence across organizations on partnered programs
• Detail-oriented mindset with excellent oral and written English communication skills 
• Must be willing to work onsite at least 4 days a week

The estimated base salary range for this role is $238,000 - $245,000. Actual pay will be based on a number of factors including experience and qualifications. This position is also eligible for two annual cash bonuses.

Who We Are:

Calico (Calico Life Sciences LLC) is an Alphabet-founded research and development company whose mission is to harness advanced technologies and model systems to increase our understanding of the biology that controls human aging. Calico will use that knowledge to devise interventions that enable people to lead longer and healthier lives. Calico’s highly innovative technology labs, its commitment to curiosity-driven discovery science, and, with academic and industry partners, its vibrant drug-development pipeline, together create an inspiring and exciting place to catalyze and enable medical breakthroughs.

Position Description:

The Director of Regulatory CMC will lead the development and execution of global CMC regulatory strategies for our pipeline of small molecules and monoclonal antibodies to accelerate clinical development and ensure seamless commercialization. Acting as a key partner to CMC and Quality, this role is responsible for the CMC content of all investigational and marketing applications, ensuring technical consistency and compliance across all stages of the product lifecycle, from early-stage development through commercialization. This role requires a blend of deep scientific fluency, meticulous attention to detail, and the ability to negotiate effectively with global health authorities. The ideal candidate has a deep understanding of the nuanced differences in regulatory pathways for both small molecules and monoclonal antibodies.

Key Responsibilities:

Regulatory Strategy and Agency Interactions

• Design and implement innovative global CMC regulatory strategies to secure approvals and maintain compliance for clinical and commercial products, identifying potential risks and creating robust mitigation plans
• Provide expert guidance on CMC requirements for both Small Molecules (NCEs) and Biologics (mAbs), including comparability protocols and stability requirements
• Act as the primary CMC point of contact for the FDA, EMA, and other global health authorities
• Lead preparations for and represent the company in formal regulatory meetings and in generating responses to Health Authority queries
• Assess the impact of manufacturing changes on global registrations and determine the necessary reporting categories globally
• Define the necessary data packages to support post-approval supplements

Submissions and Document Leadership

• Author or direct the preparation, authoring, and technical review of CMC sections for global filings:

-ND/IMPD: Investigational applications for early-phase trials

-NDA/BLA/MAA: Marketing applications for US, EU, and other major markets

• Manage the lifecycle of the Common Technical Document (CTD) specifically focusing on Module 3 (Quality) and Module 2.3 (Quality Overall Summary)

Cross-Functional Partnership

• Collaborate closely with Process Development, Analytical Development, and Quality Assurance to ensure data integrity and filing readiness
• Provide regulatory risk assessments for various manufacturing scenarios (e.g., changing CDMO sites or scaling up bioreactors)
• Monitor and stay current on the evolving CMC regulations (ICH guidelines, FDA/EMA guidance) and translate complex requirements into actionable internal plans

Position Requirements:

• B.S./M.S. in a scientific discipline (Chemistry, Biology, or Pharmacy); A Ph.D. or PharmD is highly preferred
• 10+ years of experience in the biopharmaceutical industry, with at least 7 years focused specifically on CMC Regulatory Affairs
• Successful track record of contributing to least one major marketing application (NDA or BLA) from initial drafting through approval
• Strong understanding of GMP (Good Manufacturing Practices) and ICH guidelines and deep knowledge of small molecule and mAbs modalities
• Ability to interpret complex technical data (e.g., mass spectrometry, impurity profiles, dissolution data) and effectively present it in a clear, regulatory-compliant narrative
• Deep knowledge of FDA, EMA, ICH regulations, and global regulatory requirements
• Exceptional communication and interpersonal skills, with the ability to effectively interact and influence internally with cross-functional stakeholders and senior leadership and externally with CMOs and regulatory authorities
• Must be willing to work onsite at least four days per week

The estimated base salary range for this role is $275,000 - $280,000. Actual pay will be based on a number of factors including experience and qualifications. This position is also eligible for two annual cash bonuses.

About Zipline 

Do you want to change the world? Zipline is on a mission to transform the way goods move. Our aim is to solve the world’s most urgent and complex access challenges by building, manufacturing and operating the first instant delivery and logistics system that serves all humans equally, wherever they are. From powering Rwanda’s national blood delivery network and Ghana’s COVID-19 vaccine distribution, to providing on-demand home delivery for Walmart, to enabling healthcare providers to bring care directly to U.S. homes, we are transforming the way things move for businesses, governments and consumers. The technology is complex but the idea is simple: a teleportation service that delivers what you need, when you need it. Through our technology that includes robotics and autonomy, we are decarbonizing delivery, decreasing road congestion, and reducing fossil fuel consumption and air pollution, while providing equitable access to billions of people and building a more resilient global supply chain. 

About the Role:

As the Regional Construction Manager you will own and drive all aspects of project construction to establish Zipline’s ground infrastructure in the region. This includes managing the entire process from contractor evaluation, contracting and bid evaluation, design review in partnership with our engineering teams, through to full scope site construction management and project competition  and oversight in partnership with our Service Operations and Superintendent teams. You’ll work closely with the broader Deployment and Construction team, Real Estate and Government Affairs teams, Finance, Legal, and Engineering to build strong relationships with key stakeholders and secure the necessary approvals to expand our network.

You will lead negotiations, manage external vendors, and ensure project timelines are met, all while maintaining alignment with Zipline’s strategic goals. Zipline’s Community Engagement and Legal teams will support you in fostering local partnerships and navigating jurisdictional processes to fast-track approvals.

WHAT YOU’LL DO

• Manage construction projects, site infrastructure installments, construction contractors, and additional real estate development projects ensuring schedule and cost targets are met or beaten.
• Develop and lead pre-construction strategies to streamline entitlements and permits for our ground infrastructure.
• Build and maintain strong relationships with City Managers, staff, and City Council members and inspectors to facilitate smooth approvals and permit completion from Planning and Zoning commissions and AHJ’s. 
• Collaborate closely with jurisdictions, land use counsel, and our Legal team to create pathways for drone delivery in evolving regulatory landscapes.
• Work with customer real estate teams to seamlessly integrate Zipline systems into both existing and newly designed infrastructure.
• Source and foster relationships with external stakeholders, including local jurisdictions, utilities, and contractors.
• Identify and mitigate risks associated with pre-construction and construction phases.
• Engage with partners’ Real Estate and Government Affairs teams to ensure alignment on expectations and timelines.
• Source and manage general contractors and subcontractors across various trades (construction, assembly, electrical) during bid, pre-construction, construction and site commissioning project phases. 

WHAT YOU’LL BRING

• Bachelor’s degree in Civil, Real Estate Development, Finance, Business Administration, Urban Planning, Architecture, Construction Management, or a related field 
• 6+  years of experience in real estate development or construction.
• Proven ability to manage entitlements and permits for infrastructure projects in collaboration with customers’ Real Estate and Construction teams.
• Strong communication skills with the ability to align internal stakeholders on project requirements and provide leadership with regular updates on challenges, risks, and opportunities.
• 4+ years of experience working with external design teams (Architectural, Structural, Civil, MEPs) on commercial real estate or construction projects.
• Familiarity with working alongside Authorities Having Jurisdiction (AHJs) to navigate permitting and inspection processes.
• Familiarity with construction software such as Bluebeam, Procore, and similar tools.
• Ability to travel frequently 75%+ with a near term focus in West Coast Region, an travel to our head offices in California and other domestic states, and possible international travel to support expansion projects.
• Must be eligible to work in the U.S.

What Else You Need To Know

Zipline is an equal opportunity employer and prohibits discrimination and harassment of any type without regard to race, color, religion, age, sex, national origin, disability status, genetics, protected veteran status, sexual orientation, gender identity or expression, or any other characteristic protected by federal, state or local laws or our own sensibilities.

We value diversity at Zipline and welcome applications from those who are traditionally underrepresented in tech. If you like the sound of this position but are not sure if you are the perfect fit, please apply!

If you’d like to learn more about Zipline and our teams, feel free to check out our Instagram, one of our Reddit AMA’s, or our website!

About the Role

As the Associate Regional Construction Manager you be a key stakeholder in driving all aspects of project construction to establish Zipline’s ground infrastructure in the region. This includes supporting the entire process from contractor evaluation, contracting and bid evaluation, design review in partnership with our engineering teams, through to full scope site construction management and project competition  and oversight in partnership with our Service Operations and Superintendent teams. You’ll work as a lead to the Construction Management team in region and with the broader Deployment team, Real Estate and Government Affairs teams, Finance, Legal, and Engineering to build strong relationships with key stakeholders and secure the necessary approvals to expand our network.

You will lead negotiations, manage external vendors, and ensure project timelines are met, all while maintaining alignment with Zipline’s strategic goals. Zipline’s Community Engagement and Legal teams will support you in fostering local partnerships and navigating jurisdictional processes to fast-track approvals.

This role is well suited to an early career Construction Manager looking to take on more scope, responsibility and ownership across the entire project lifecycle - if you are looking to do more, see more and own more this is the job for you!

What You'll Do

• Support construction projects, site infrastructure installments, construction contractors, and additional real estate development projects ensuring schedule and cost targets are met or beaten.
• Develop and lead improvements to construction methods and processes.
• Develop and lead pre-construction strategies to streamline entitlements and permits for our ground infrastructure.
• Build and maintain strong relationships with City Managers, staff, and City Council members and inspectors to facilitate smooth approvals and permit completion from Planning and Zoning commissions and AHJ’s. 
• Collaborate closely with jurisdictions, land use counsel, and our Legal team to create pathways for drone delivery in evolving regulatory landscapes.
• Work with customer real estate teams to seamlessly integrate Zipline systems into both existing and newly designed infrastructure.
• Source and foster relationships with external stakeholders, including local jurisdictions, utilities, and contractors.
• Identify and mitigate risks associated with pre-construction and construction phases.
• Engage with partners’ Real Estate and Government Affairs teams to ensure alignment on expectations and timelines.
• Source and manage general contractors and subcontractors across various trades (construction, assembly, electrical) during bid, pre-construction, construction and site commissioning project phases. 

What You'll Bring

• Bachelor’s degree in Engineering (Civil, Mechanical, Structural), Real Estate Development, Finance, Business Administration, Urban Planning, Architecture, Construction Management, or a related field 
• 3+  years of experience in real estate development or construction.
• Strong communication skills with the ability to align internal stakeholders on project requirements and provide leadership with regular updates on challenges, risks, and opportunities.
• Familiarity with construction software such as Bluebeam, Procore, and similar tools.
• Ability to travel frequently 75%+ with a near term focus in West Coast Region, and travel to our head offices in California and other domestic states, and possible international travel to support expansion projects.
• Must be eligible to work in the U.S.

What Else You Need To Know

Zipline is an equal opportunity employer and prohibits discrimination and harassment of any type without regard to race, color, religion, age, sex, national origin, disability status, genetics, protected veteran status, sexual orientation, gender identity or expression, or any other characteristic protected by federal, state or local laws or our own sensibilities.

We value diversity at Zipline and welcome applications from those who are traditionally underrepresented in tech. If you like the sound of this position but are not sure if you are the perfect fit, please apply!

If you’d like to learn more about Zipline and our teams, feel free to check out our Instagram, one of our Reddit AMA’s, or our website!

About the Role >>> Senior Director, Global Regulatory Strategy 

As the Senior Director, Global Regulatory Strategy reporting to the Senior Vice President of Regulatory Affairs, your main responsibilities will include the following:  

• Leading the development and execution of innovative regulatory strategies supporting Olema products  
• Representing Regulatory Affairs on cross-functional teams as the subject matter expert and providing regulatory guidance and oversight to the global project teams
• Providing strategic and tactical guidance and leading the development of regulatory submissions (INDs, CTx, briefing documents, IB, NDA, BLA, IMPD etc.)  

This role is based either out of our Boston, MA or San Francisco, CA office and will require domestic and international travel up to 20%. 

Your work will primarily encompass:  

• Develop innovative global regulatory strategies for the Olema portfolio of products, in clinical development and life-cycle management, as needed  
• Represent Regulatory Affairs as the SME across cross-functional teams and provide regulatory guidance/oversight to the global project teams, Study Execution Teams, and the Executive Committee  
• Stay abreast of the regulatory landscape and regulatory requirements impacting drugs, biologics and devices (e.g., companion diagnostics)  
• Be accountable for, provide both strategic and tactical guidance and lead the development of regulatory submissions (INDs, CTX, briefing documents, IB, NDA, BLA, DSUR, IMPD etc.)  
• Represent Olema with global Health Authorities and lead Agency interactions to achieve company objectives  
• Proactively identify gaps and develop risk mitigation strategies for regulatory submissions in alignment with the team(s) and management 
• Ensure Olema’s regulatory activities are robust and in compliance with Health Authority (HA) regulatory requirements  
• Coordinate and maintain all HA reporting schedules in collaboration of cross-functional teams  
• Serve as the point of contact with external parties and vendors supporting regulatory activities (e.g., CROs, contractors etc)   
• Participate in and contribute to cross-functional and departmental objectives  
• Maintain flexibility to adapt and accommodate additional duties as assigned  

And will also include the following:  

• Lead the development of Regulatory Affairs department policies, SOPs, and work instructions  
• Provide Regulatory guidance and leadership to cross-functional teams on software implementation for Regulatory dossiers (e.g., Veeva)  
• Keep the Leadership and the organization fully informed of the regulatory landscape, including HA initiatives, policies and their potential impact on Olema’s programs  
• Lead the global Regulatory team(s) and ensure execution of the regulatory strategies to achieve company objectives  
• Mentor and develop colleagues in the Regulatory department   

Ideal Candidate Profile  >>> Innovative Experienced Regulatory Strategy Leader  

A love of challenging, important work. We are a pragmatic team, driven to imagine and develop meaningful therapies for improving lives. All employees within our company play a unique and crucial role in our success, both in accomplishing our mission and building a positive company culture. As such, we are looking for someone with the right combination of knowledge, experience, and attributes for this role.  

Knowledge:  

• Bachelor’s degree in a scientific discipline  
• Advanced degree in scientific discipline Masters, Pharm D or PhD is preferred   

Experience:  

• 12 years’ experience in Regulatory Affairs in Pharma/Biotech  
• Minimum of 3 years direct leadership experience  
• Strong negotiation skills with health authorities (viz., FDA, EMA, Health Canada, etc.) as well as submissions  
• Experience with leading the NDA/BLA or Marketing Applications is desirable.) 
• Experience in Oncology Therapeutic area is required 
• Experience with development and execution of regulatory strategies in Oncology TA is required  
• Ability to work in a fast-paced environment in a hands-on fashion  
• Excellent oral, written, and presentation skills  
• Strong organizational skills  

Attributes:  

• Self-starter  
• Flexible and proactive, with the ability to manage multiple projects and successfully adapt to changing business needs and priorities

The base pay range for this position is expected to be $270,000 - $290,000 annually, however the base pay offered may vary depending on location, market, job related knowledge, skills and capabilities, and experience. The total compensation package for this position also includes equity, bonus, and benefits. 

#LI-MK1

Senior Solutions Engineer

This role will contribute to both commercial and our US government programs.

Role

As a Senior Solutions Engineer you will be working on satellite network design and analysis for global commercial and government solutions. This role will focus on pre-sales engineering for commercial pursuits, but also support post sales engineering and internal development efforts. At its core, this involves optimizing high throughput satellite networks, from design to operation, by understanding and trading dozens of parameters, including but not limited to: 

• Satellite communications payload configuration and development
• Orbital slot selection, spectrum, and frequency planning 
• Antenna system optimization, user coverage area definition
• User terminal selection
• Networking / modem equipment selection and configuration 
• Gateway and remote earth station selection
• Baseband selection to meet the client’s specific use case

This is an exciting multi-dimensional role that provides a balance of technical and business / customer facing responsibilities, and is high visibility and high impact. Our responsibilities include:

• Create satellite network solutions for commercial pursuits all the way through deal closure and beyond.
• Modeling and analyzing satellite networks using in house network software
• Interfacing with Commercial, US Government, Finance, Legal, Engineering, Operations, Regulatory and Executive teams
• Communicate our satellite network designs and reports externally as solutions/sales engineers
• Aid in regulatory (FCC, ITU, etc.) efforts regarding spectrum use and coordination
• Aid and influence the design of analysis software that enables us to excel in our role.
• Define product market fit for next generation satellite communication systems
• Dimensioning ground solutions for commercial pursuits by working with Earth Stations Engineering/Operations, Network Operations, and Hub teams
• Building Astranis’s profile with the international business community
• Maintain healthy relationships with vendors and partners such as network hardware/service suppliers, hub vendors, and terminal suppliers for satellite networks
• Shaping our future product offering based on current trends, market insight, and customer feedback
• Assisting in recruiting, interviewing, and hiring additional teammates to our rapidly-growing team
• Willingness to travel (Up to ~20%)

Requirements 

• 5+ years in satellites communications industry experience with High Throughput Satellite (HTS) systems including ground, hub, and network systems for LEO, MEO, or GEO 
• Bachelor of Science degree in Aerospace Engineering, Electrical Engineering, Computer Science, or Physics  (or equivalent background knowledge) 
• Enjoy working in a fast paced environment and shaping process and procedures for long term growth
• Link budgeting / Link analysis experience
• Experience with regulatory affairs for space based communications networks
• Experience with satellite network hub management and operations
• Proven track record in strategic technical sales environments balancing the customers’ wants with internal capabilities and goals
• Scripting language experience in one of the following: Python (preferred), MATLAB, R, Julia, C++, or similar. Comfortable using scripted tools to conduct analyses and trade studies. 
• Must be onsite in San Francisco
• Don't meet them all? Not a problem. Please apply even if you do not meet all these criteria.

Bonus  

• Experience in cellular 3g, 4g, LTE, and 5g network protocol
• Experience in SD-WAN architecture
• Experience working Military Satellite communications systems

What You'll Do

The AD/Director, Marketing – Patient will lead the development and commercialization of key assets, with primary responsibility for driving integrated patient marketing strategy in the US. This role will provide strategic leadership across patient-facing initiatives for the commercial launch and growth of BBP-418 and future assets. The Director will ensure strong cross-functional collaboration and alignment, translating market insights into impactful strategies and tactics that drive adoption, access, adherence, and brand growth.

This individual will serve as a core leader on commercial product teams and work closely with Market Insights, Market Access, Regulatory, Medical Affairs, Commercial Operations, Digital, Advocacy, and Regional teams to deliver cohesive, high-impact commercial planning and execution. The Director should thrive in a fast-paced, highly collaborative, and ambiguous environment, bringing strong strategic thinking, executional excellence, and people leadership to the organization. This role reports to the SVP, Sales & Marketing.

Responsibilities

• Provide strategic leadership as a senior commercial member on Product Teams, embedding patient market needs into cross-functional planning and decision-making
• Lead integrated brand strategy across patient audiences, including brand positioning, messaging, claims, and narrative development
• Oversee the development and execution of innovative, data-driven patient marketing campaigns that inspire behavioral change and drive brand growth, ensuring consistent execution across channels and functions
• Champion patient-centric marketing by identifying unmet patient and caregiver needs and translating insights into impactful education, engagement, advocacy, access, and adherence initiatives
• Lead patient ambassador and advocacy-related initiatives in partnership with advocacy and medical teams
• Drive disease education strategy across audiences, including patient, caregiver, educational resources and campaigns
• Partner with Value and Access to shape value propositions, access, reimbursement, and patient support strategies that enable optimal patient access
• Collaborate with Commercial Operations, Digital, IT, MCM, and agency partners to build a cohesive customer engagement ecosystem
• Proactively assess market dynamics, competition, clinician practices, and evolving patient and HCP needs to inform strategic adjustments
• Develop and oversee measurement frameworks, KPIs, and analytics to evaluate performance, prioritize investments, and optimize impact across patient and HCP tactics
• Ensure diverse regional and field insights are incorporated into planning and execution, serving as the commercial voice advocating for these perspectives
• Lead, mentor, and develop marketing team members, fostering a culture of accountability, collaboration, innovation, and continuous improvement
• Collaborate closely with the lead on HCP strategy, engagement and tactics and support work as needed

Where You’ll Work

This is a hybrid role and requires in-office collaboration 2-3x per week in our San Francisco Office.

Who You Are

• 5+ years of commercial biotech or pharmaceutical experience, with at least 5 years in progressively responsible marketing roles
• Demonstrated experience leading brand strategy and execution across both patient and HCP audiences
• Experience/knowledge in TA of Neurology
• Proven launch experience, preferably in competitive and/or rare disease markets
• Strong understanding of the drug development process and opportunities for differentiation and value communication
• Demonstrated ability to translate complex clinical data and market research into actionable insights and strategy
• Experience leading cross-functional teams and agency partners, with a track record of delivering results in ambiguous environments
• Excellent oral, written, and presentation skills, with the ability to influence senior stakeholders
• Passionate about serving patients suffering from genetic diseases and advancing therapies for underserved populations
• Self-starter with strong ownership mindset, able to manage multiple priorities and deliver high-quality outcomes
• High level of self-awareness and commitment to continuous learning and improvement
• Entrepreneurial mindset aligned with BridgeBio’s mission to do things differently, driven by science and an unrelenting focus on patients
• Ability to travel approximately 20–25%#I-NT1

About You and The Role 

As a Development & Permitting Project Manager, you will be responsible for driving the expansion of our network - defining how autonomous aerial logistics integrates into the built environment at scale. You are the single-threaded owner of development outcomes from site identification through entitlements, permitting and approvals across multiple metros, often simultaneously and under real deadlines.

We are looking for someone who takes ownership seriously - someone organized, highly detail-oriented, and consistent in follow-through. You are a self-starter who can operate independently, make decisions with incomplete information, and drive outcomes without constant direction. The work will be ambiguous at times; the expectation is that you bring structure and clarity to it.

This role sits at the intersection of site acquisition, real estate development, land use, aviation, and regulatory strategy. You will work closely with government affairs and legal land use to unlock jurisdictions that have never approved infrastructure like ours before. The playbook is being written - and you will help create it. Success requires sound judgment, persistence, and the ability to move projects forward in environments that are ambiguous, slow-moving, or resistant.

You will partner closely with engineering and operations to solve technical and site-specific challenges and ensure projects are executable - not just approvable. You should be comfortable going deep on drawings, constraints, and tradeoffs while still maintaining forward momentum.

This is an in-person position based out of our regional office in metro. Candidates must be local to the area and bring existing, credible relationships with AHJs and permitting authorities. This is not a role where you build your network from scratch.

What You'll Do

• Real Estate Search & Site Development:
• Support site selection, feasibility, and risk assessment end-to-end, ensuring alignment with zoning, land use, and aviation constraints.
• Identify risks early and drive mitigation plans across permitting, environmental, and infrastructure considerations before they impact timelines.
• Partner with engineering to translate site constraints into clear design requirements and ensure permit-ready drawings.
• Land Use Approvals & City Permitting:
• Build and maintain strong working relationships with planners, zoning officials, and building departments to move projects forward efficiently.
• Lead permitting efforts across multiple metros, including navigating novel regulatory pathways for drone operations.
• Partner with government affairs to navigate and, where necessary, help shape regulatory approaches.
• Represent Zipline in public forums (Planning & Zoning, City Council), communicating clearly and effectively to secure approvals.
• Ensure all submittals are complete, accurate, and aligned with jurisdictional requirements - high attention to detail is critical.
• Actively manage permitting timelines by engaging directly with departments, resolving issues, and escalating when appropriate.
• Pre-Construction:
• Support the building permit process from submission through approval, ensuring accuracy, completeness, and timeliness.
• Work with external consultants to produce high-quality, compliant drawings and documentation.
• Support contractor engagement and scope definition to ensure a smooth transition to the construction team.
• Cross-Functional Coordination:
  • Collaborate with site acquisition, engineering, regulatory, legal land use and operations teams to ensure alignment across development and execution.
  • Surface risks early and propose practical solutions to keep projects moving.
  • Provide clear input on permitting and policy considerations during site selection and deal review.

What You'll Bring

• Bachelor’s degree in Engineering (Civil, Mechanical, Industrial, Electrical, Others), Real Estate, Development, or Construction Management.
• 5+ years of experience in Real Estate Development, Permitting, Urban Planning, Civil Engineering, and/or Public-Private Project Development, with a track record of delivering projects from concept through approvals.
  • Bonus: Professional Engineering (Civil) License in the State of Texas, Florida, Arizona, Georgia or California and ability to stamp drawings.
• Strong understanding of zoning laws, building codes, and regulatory processes, with the ability to navigate them independently.
• Proven experience managing entitlements, permitting, and development projects in coordination with real estate and construction teams.
• Proficiency in tools such as Smartsheet and Bluebeam (Revit / AutoCAD a plus), with the ability to review and interpret drawings.
• Ability to work effectively with government officials, permitting agencies, and community stakeholders to secure approvals.
  • Bonus: Experience in aviation, logistics, or other highly regulated infrastructure environments.
• Strong communication skills, including experience presenting in public meetings or similar forums.
• Established local relationships with AHJs and permitting authorities that can be leveraged immediately.
• Willingness to travel up to 50% across the state to support expansion efforts.
• Must be eligible to work in the US.

What Else You Need to Know   

This role will serve as a strategic and operational partner to the Vice President of Medical Affairs and Medical leadership team, and is responsible for ensuring that medical capabilities, processes, systems, and execution models are efficient, compliant, scalable, and aligned with Alumis’ growth strategy. The Senior Director, Medical Strategy and Operations, will be responsible for advancing key initiatives aimed at optimizing and showcasing the impact of the Medical Affairs team. This is a hands-on position that includes driving medical strategic initiatives, enhancing the Medical Affairs systems, supporting critical medical insights processes, and developing innovative solutions to measure and report on medical affairs performance and impact. The role demands an individual who combines scientific knowledge with strong operational leadership to thrive in a fast-paced, agile environment to elevate our medical affairs capabilities.

Key Responsibilities:

· Strategic Leadership: Lead and drive the development and execution of initiatives that elevate the strategic and operational effectiveness of the Medical Affairs team in a consistent and scalable manner.

· Medical Affairs Systems Optimization:

o Oversee the design, implementation, and optimization of our Medical Affairs systems to improve internal efficiencies, engagement and communications with key opinion leaders (KOLs), healthcare providers, and other relevant stakeholders.

o Lead continuous improvement initiatives to enhance efficiency, quality, and compliance across the Medical function.

o Implement best practices for operational metrics, KPIs, dashboards, and reporting to support data-driven decision-making.

· Medical Insights: Collaborate with Medical Affairs Leadership to collect, analyze, and integrate valuable medical insights that inform strategic decisions and optimize the impact of our medical programs.

· Content Management: Serve as Medical Affairs content owner through review and approval process for external-facing materials.

· Cross-functional Collaboration: Collaborate with other functional areas such as Clinical Development, Marketing, Market Access, Commercial, Analytics, Compliance, and Regulatory to ensure alignment and integration of medical excellence within the broader organizational strategy.

· Guidance and SOP Development: Leverage expertise to develop guidance documents and SOPs to foster consistency, clarity, and accountability across Medical Affairs.

· Planning, Budgeting & Resource Management

o Lead medical annual planning, forecasting, and budget management.

o Optimize headcount planning, vendor strategy, and external spend to maximize impact and efficiency.

o Provide transparency and insights into medical investments and their impact.

Qualifications:

· Experience: Minimum of 10 years in Medical Affairs leadership. Proven experience in managing and optimizing medical operations, systems, content, and medical insights. Experience in a fast-paced, small biotech environment a plus

  Education: Advanced degree (PhD, MD, MBA, PharmD or similar)

· Leadership Skills: Exceptional leadership abilities with a demonstrated ability to manage cross-functional teams and drive change across complex medical operations. Must have track record of effectively leading without authority

· Operational Expertise: Strong experience in developing and managing Medical Affairs dashboards and other qualitative outcomes to measure impact and performance.

· Strategic Thinking: Ability to develop and implement strategic initiatives aligned cross-functionally that drive organizational goals and enhance the impact of Medical Affairs functions.

· Strong Communication: Excellent communication and interpersonal skills, with the ability to engage and influence stakeholders at all levels, both internally and externally.

The salary range for this position is $265,00 to 310,000 USD annually. This salary range is an estimate, and the actual salary may vary based on the Company’s compensation practices degree and background.

Alumis Inc. is an equal opportunity employer.

Alumis compensation packages include generous stock option grants for all employees as well as an annual bonus program.  

Other benefits include:

• Health insurance premiums paid at 90% for employee, 80% for dependents
• Free access to Genentech Bus & Ferry Share program
• $100 monthly cell phone stipend
• Unlimited PTO for Exempt employees
• Free onsite gym and a kitchen stocked with yummy snacks and drinks!

We are a hard-working, collaborative team on a mission to transform patient’s lives-- and we aspire to elevate, challenge and nurture one another along the way.

Your Impact

You will design and lead the strategy that unlocks scalable procurement and partner-driven growth across our US Public Sector business. By building and optimizing our state and cooperative contract portfolio, activating high-impact commercial partnerships, and proactively clearing procurement hurdles for new products, you will remove friction from the buying process, expand market access and accelerate revenue growth. This role sits at the intersection of Sales, Legal, Product, Finance, and Government Affairs — translating go-to-market priorities into executable contracting and commercialization frameworks that drive measurable growth.

What You’ll Do

Location: This role is based out of our San Francisco, CA office and follows a hybrid schedule. We rely on in-person collaboration and ask that team members work onsite Tuesdays through Fridays, with the flexibility to work remotely on Mondays, unless there is an approved workplace accommodation. We believe that connection fuels innovation, and our in-office culture is designed to foster meaningful teamwork, mentorship, and shared success.
Reports to: Senior Director, Strategy & Enablement
Direct Reports: None

State & Cooperative Contract Strategy

• Develop and execute a forward-looking state and cooperative contract strategy aligned to go-to-market priorities; anticipate procurement needs 12–18 months in advance and establish required vehicles ahead of revenue timelines.
• Establish, expand, and renew statewide and cooperative contracts to include new products, services, and pricing models that support growth objectives.
• Lead negotiations for new and expanded contracts, aligning Legal, Sales, Finance, and external stakeholders to secure favorable commercial and operational terms.
• Own strategic relationships with cooperative purchasing organizations and evaluate new vehicles based on revenue potential and market coverage.
• Track contract utilization and performance, identifying opportunities to optimize scope, usability, and adoption across priority markets.

Commercial Partner Strategy & Activation

• Operationalize new commercial partnerships identified by Corporate Development by designing the revenue activation plan and establishing repeatable pathways to secure the first deals on Axon paper.
• Identify priority accounts and use cases where partner products strengthen Axon’s solution; align Sales, Product, Marketing, and the partner on positioning, pricing, and enablement readiness.
• Build scalable procurement and contracting frameworks that allow Axon to compliantly resell partner products within public sector constraints, tracking early performance and refining activation strategy based on results.

New Product Growth Enablement

• Proactively identify and remove procurement, contracting, and regulatory barriers that could delay adoption of new products in state and local markets.
• Ensure state-specific requirements and contract inclusion strategies are understood early and addressed in alignment with launch revenue timelines.
• Translate complex procurement considerations into actionable guidance for Sales and Enablement teams.

What You Bring

• 7+ years of experience in public sector strategy, government contracting, channel/partner strategy, business development, or sales operations within a complex, multi-stakeholder environment.
• Demonstrated success designing and executing strategies that expanded market access and accelerated revenue growth.
• Experience operationalizing commercial partnerships or resell models, translating partnership agreements into executable revenue plans.
• Comfortable balancing legal, financial, and commercial considerations in negotiations.
• Proven ability to influence senior stakeholders and drive cross-functional alignment without direct authority.
• Experience supporting new product launches or commercialization strategies within regulated or procurement-constrained markets.
• Analytical mindset with ability to assess performance metrics, identify friction points, and refine strategy based on data.
• Strategic thinker with a bias for action and a track record of delivering complex, long-horizon initiatives to completion.
• Deep understanding of public sector procurement, including statewide master contracts and cooperative purchasing organizations is a plus.
• Experience in Government Technology, SaaS, or Public Safety Technology preferred.

Benefits that Benefit You

• Competitive salary and 401k with employer match
• Discretionary paid time off
• Paid parental leave for all
• Medical, Dental, Vision plans
• Fitness Programs
• Emotional & Mental Wellness support
• Learning & Development programs
• And yes, we have snacks in our offices

Benefits listed herein may vary depending on the nature of your employment and the location where you work

What You'll Do

The Associate Medical Director, Endocrinology - is a medical and scientific leadership role within United States Medical Affairs that supports development and execution of the Medical Affairs strategy for encaleret across clinical development programs, including autosomal dominant hypocalcemia type 1 (ADH1) and chronic hypoparathyroidism, with focus on launch readiness and lifecycle planning grounded in scientific rigor and patient focused decision making.

This position partners across Clinical Development, Scientific Communications, Congress Operations, Regulatory, Commercial, Patient Advocacy, and Field Medical to support trial execution, data disclosure and publication planning, peer to peer scientific exchange, and coordinated congress strategy and materials. The Associate Medical Director also supports strategic external relationships with investigators, key opinion leaders, and other stakeholders and co-leads advisory boards and expert panels to inform Medical Affairs programs and priorities.

Responsibilities

• Support development and execution of the United States Medical Affairs strategy for encaleret in ADH1 and chronic hypoparathyroidism, including launch readiness and lifecycle planning with scientific rigor and patient focused decision making
• Support integrated evidence generation planning and execution, including real world evidence, Phase 4 studies, registries, investigator-initiated research support, and data integration activities
• Support omnichannel HCP engagement by enabling field and digital scientific exchange, gathering insights, and translating themes into Medical Affairs programs and tactics
• Support strategic relationships with key opinion leaders, investigators, and external stakeholders across endocrinology, nephrology, and related specialties, and co-lead advisory boards and expert panels
• Partner with Clinical Development to support ongoing and planned clinical trials and contribute to data disclosure and publication planning with Scientific Communications
• Support peer to peer scientific exchange and external education programs, including congress and clinical meeting preparation and scientific materials development
• Partner with Congress Operations and Scientific Communications to define congress strategy, align scientific narratives and data priorities, and deliver coordinated pre congress, onsite, and post congress medical plans
• Ability to travel up to ~40% for scientific meetings, advisory boards, and internal engagements

Where You'll Work

This is a hybrid role and requires in-office collaboration 3x per week in our San Francisco and Palo Alto Offices.

Who You Are

• MD, DO, PharmD, PhD, or equivalent advanced scientific or clinical degree
• 4+ years of experience in Medical Affairs, Clinical Development, or related roles within the biopharmaceutical industry and/or academic medicine
• Field Medical Affairs experience and field insight generation, is a plus
• Demonstrated experience supporting late-stage development, launch preparation, and post-marketing medical activities
• Strong scientific and clinical acumen with the ability to translate complex data into clear medical insights
• Proven leadership and influence in cross-functional, matrixed environments
• Excellent written and verbal communication skills
• Strong understanding of regulatory and compliance requirements impacting Medical Affairs and field activities
• Ability to work independently in a fast-paced, evolving organization
• Strategic mindset with hands-on execution capability

#LI-SS1

About the role

Sana Biotechnology is growing, and we are hiring new team members who believe in the potential of engineered cells as medicines, who are passionate about delivering the possible to patients, and who lead with the desire to work on novel ideas. We are seeking an accomplished and strategic Senior Director, Regulatory Affairs to shape global clinical regulatory strategy across our pipeline, with a particular focus on programs in Type 1 diabetes, oncology, and autoimmune disease. This role is ideal for a seasoned regulatory leader who is excited by science‑driven development, cross‑functional collaboration, and advancing therapies for serious diseases.

You will develop and execute comprehensive regulatory strategies for clinical‑stage programs, guide teams on global regulatory requirements, and help shape the long‑term regulatory vision for the portfolio from Phase 1 to commercialization. Clinical-stage regulatory experience in our therapeutic areas of focus (Type 1 diabetes, oncology, autoimmune disease) and cell/gene therapies is preferred. Experience in regulatory operations and/or ex-US submission planning are also considered beneficial for the role. This position reports to the Vice President, Head of Regulatory Affairs and would work out of Sana’s offices in Cambridge (preferred), South San Francisco, or Seattle.

What you’ll do

• Direct clinical regulatory strategies for assigned programs, with emphasis on Type 1 diabetes, oncology, and autoimmune disease assets.
• Create regulatory development plans, including key milestones, registration strategies, health authority engagement plans, expedited pathways, pediatric development, and risk assessments.
• Partner closely with Clinical Development, CMC Regulatory Affairs, Clinical Operations, Safety, Technical Operations, and Program Leadership.
• Lead and/or oversee global regulatory submissions and health authority interactions/meetings.
• Provide strategic input into labeling, target product profiles, and benefit‑risk considerations.
• Serve as a senior regulatory representative on cross‑functional program teams.
• Lead regulatory operations improvement efforts to ensure submission quality, compliance, and efficiency.
• Proactively identify regulatory risks and mitigation strategies.
• Monitor evolving regulatory policy in Sana’s therapeutic areas of focus and for cell/gene therapy modalities.
• Support development of internal regulatory processes.
• Mentor junior regulatory staff.

What we’re looking for

• Bachelor’s degree required, advanced degree in relevant scientific field preferred.
• 10+ years of regulatory affairs experience in biopharmaceutical industry; experience with cell and/or gene therapy products highly desirable.
• Demonstrated success in preparing and leading IND/CTA submissions, pivotal-stage amendments, BLA/MAAs, and any associated regulatory interactions.
• Clinical-stage regulatory experience in Sana’s therapeutic areas of focus (Type 1 diabetes, oncology, autoimmune disease) and cell/gene therapies preferred.
• Demonstrated ability to lead regulatory strategy through complex decision points and influence cross-functional teams at the senior level.
• Demonstrated ability to collaborate productively across a broad array of functional areas, as well as raise and entertain different points of view and regulatory options.
• Experience in regulatory operations, and/or ex-US submission planning beneficial, though not required.
• Strong understanding of FDA, EMA, and international guidelines.
• Excellent oral and written communication skills.
• Ability to work from Sana offices in Cambridge, MA is preferred; will consider candidates who can work from our offices in South San Francisco, CA or Seattle, WA.

What will separate you from the crowd

• Deep motivation to advance therapies for people with serious unmet needs.
• Intellectual curiosity and scientific rigor.
• Strong skills in matrix leadership, influencing without direct authority

What you should know

• The base pay range for this position at commencement of employment is expected to be between $275,000 and $325,000/year; however, base pay offered may vary depending on multiple individualized factors, including market location, job-related knowledge, skills, and experience 

Alumis Inc. is a precision medicines company with the mission to transform the lives of patients with autoimmune diseases. Even with treatment innovations of the last two decades, many patients with immunologic conditions continue to suffer - our goal is to fundamentally change the outcomes for these patients. 

Alumis is seeking an experienced Director of Thought Leader Liaison (TLL) with deep expertise in Dermatology. This role is a field-based commercial leadership role responsible for leading a team of field based TLLs, to develop and execute Key Opinion Leader (KOL) engagement strategies for the US launch of envudeucitinib for Psoriasis. 

The successful candidate will be a key member of the brand marketing team, working across multiple stakeholders at the intersection of marketing, medical, and field execution, with accountability for team leadership, KOL strategy and execution, and strategic insight generation to shape brand strategy. This role will require a deep understanding of medical science, excellent leadership capabilities, and a strong ability to drive the success of cross-functional teams. 

Key Responsibilities:

Leadership & Team Management

• Build, lead and manage a team of TLL reports with the responsibility for coaching, developing, assessing performance, delegation, prioritization and fostering a collaborative and high performing culture.
• Collaborate with the Marketing leadership team to align TLL activities with organizational priorities and strategic initiatives.
• Set the direction and manage the cross functional collaboration and coordination of the TLL team with key stakeholders for development and execution of key brand activities and tactics.
• Conduct regular performance evaluations, identify skill gaps, and support TLL development through coaching, training, and career growth opportunities.

Strategic Planning & Execution

• Design and implement an engagement strategy in partnership with Marketing and other key stakeholders to guide interactions between the TLL team and KOLs.
• Oversee the identification, establishment, and maintenance of the TLL thought leader community, ensuring alignment with Medical Affairs and other key stakeholders.
• Drive development and execution of key strategies and tactics to high standards whilst delivering exceptional customer experiences.
• Initiates and pursues opportunities for commercial engagement at national and regional conferences, key advocacy or healthcare stakeholder meetings. and represent Alumis at these events.

KOL Relationship Management

• Cultivate strong, long-lasting relationships with existing and new KOLs to gather feedback on market dynamics, competitive landscape, marketing strategy, and tactical execution.
• Serve as a marketing resource and point of contact for KOLs.
• Represent the company at scientific congresses, advisory boards, speaker bureau events and other relevant forums to enhance scientific and therapeutic understanding.

Compliance & Reporting

• Ensure all TLL activities are conducted in compliance with regulatory, ethical, and company standards, HIPAA regulations.
• Provide regular updates to Marketing management on team progress, KOL engagement, and other key initiatives, including metrics on impact and outcomes.
• Stay abreast of the competitive landscape and emerging trends in dermatology, rheumatology, and neurology, ensuring TLL activities reflect the latest scientific advancements.

Qualifications:

Experience

• Minimum of 10 years of experience in TLL or related roles, with leadership experience in managing a team of TLLs.
• Deep experience in therapeutic area of medical dermatology.
• In-depth knowledge of medical dermatology, including clinical practice, research, and evolving treatment paradigms.
• Proven track record of successful relationship-building with KOLs, HCPs, and key stakeholders within the medical community.
•  Experience working in cross-functional teams, with a demonstrated ability to collaborate effectively with medical affairs, clinical, and other business functions.

Skills & Competencies

• Excellent leadership and team management skills, with the ability to inspire and develop a high-performing team.
• Previous experience working in a leadership role within a biopharmaceutical company or a global pharmaceutical organization.
• Comfort at presenting team activities to C-suite.
• Strong communication, presentation, and interpersonal skills, with the ability to engage effectively with internal and external stakeholders.
• Deep understanding of the pharmaceutical industry, including regulatory and compliance requirements, scientific data dissemination, and account or relationship management.
• Ability to translate information including scientific, into actionable insights for diverse audiences, including KOLs, healthcare professionals, and internal teams.
• Strong problem-solving, strategic thinking, analytical and decision-making skills.
• Agile, solutions-oriented leader with a strong bias for action.
• Bachelor’s degree required.

Travel

• This position is primarily remote with travel.
• Willingness to travel extensively (50-75%) as required for KOL engagement, scientific meetings, brand activities and team management activities
• Regular travel to HQ expected

Alumis Inc. is an equal opportunity employer.

Alumis compensation packages include generous stock option grants for all employees as well as an annual bonus program.  The salary range for this position is $215,000-$260,000 USD annually. This salary range is an estimate, and the actual salary may very based on the Company’s compensation practices degree and background.

Alumis compensation packages include generous stock option grants for all employees as well as an annual bonus program.  

Other benefits include:

• Health insurance premiums paid at 90% for employee, 80% for dependents
• 401k match
• Free access to Genentech Bus & Ferry Share program
• $100 monthly cell phone stipend
• Unlimited PTO 
• Free onsite gym and a kitchen stocked with yummy snacks and drinks!

We are a hard-working, collaborative team on a mission to transform patient’s lives-- and we aspire to elevate, challenge and nurture one another along the way.

The Lead Affiliate Counsel is the single point of legal contact for one or more BridgeBio affiliates — the person the affiliate head calls first on everything. Not just commercial questions. Not just MLR. Everything. You will own the legal relationship with the affiliate, quarterback the full breadth of legal support across the BridgeBio legal team and ensure that the affiliate gets the quality and speed of counsel it needs to operate with confidence. 

This is a role for a lawyer who is as comfortable thinking about a contract dispute as they are about a promotional compliance question or an employment matter — and who has the presence, judgment, and organizational intelligence to be a genuine trusted advisor to business leaders. You will not do every piece of legal work yourself. But you will own every piece of it, and the affiliate will always know where you stand. 

WHAT YOU'LL DO 

At BridgeBio each product is not just a business unit. To serve patients in need and be nimble we believe each product deserves its own affiliate, with a central hub providing the necessary services. As Lead Affiliate Counsel, you are the legal face of BridgeBio to one or more of these affiliates. You own the relationship with affiliate leadership, quarterback the full scope of legal support across the BridgeBio legal team, and ensure your affiliate operates with confidence on every legal matter — from commercial strategy to compliance to contracts to employment. You are a trusted advisor and integrator first, and a specialist second. 

Affiliate Legal Partnership 

• Serve as the single point of legal contact for one or more affiliate heads — their first call on any legal matter, regardless of subject area, and the person who ensures nothing falls through the cracks 

• Quarterback legal support across the BridgeBio legal team — knowing when to handle matters directly and when to pull in specialists across commercial, employment, IP, regulatory, or finance law, while maintaining ownership of the relationship and quality of the work product 

• Provide strategic legal counsel across the full scope of affiliate activities — commercial strategy, HCP and HCO engagement, promotional materials, patient programs, payer and market access, contracts, and operational matters — with the breadth of a general counsel and the judgment to know which issues require deeper specialist engagement 
• Work across Commercial, Medical Affairs, Finance, HR, Compliance, and Regulatory functions both within the affiliate and across BridgeBio to drive issues to resolution efficiently — the affiliate should always feel that legal has it handled 

MLR & Promotional Review 

• Participate as a member of the Material Review Committee (MLR), collaborating with Medical Affairs and Regulatory to ensure promotional and scientific materials are accurate, balanced, and compliant — bringing legal judgment that is enabling, not obstructive 

• Help the business communicate effectively about its medicines — finding the path to yes wherever possible, and explaining clearly when the answer must be no 
• Partner with Compliance and Regulatory to develop and continuously improve MLR processes and standards that scale with a growing, multi-product commercial organization 

Risk & Compliance Partnership 

• Identify and flag legal and reputational risk across affiliate activities proactively — before issues escalate — and work with the right people across the legal team to address them 

• Partner with the Head of Compliance on healthcare fraud and abuse matters — AKS, FCA, and related considerations — ensuring legal and compliance work in lockstep to give the affiliate consistent, coherent guidance 
• Be the person the affiliate can always reach — responsive, decisive, and clear. In a fast-moving commercial environment, good legal counsel means knowing when to move quickly and when to slow down 

WHAT THIS ROLE REQUIRES 

• You are motivated by the patients at the end of every decision. You chose this work because it matters — and at BridgeBio, the connection between legal excellence and patient impact is not abstract. It is real. 

• You are a natural quarterback. You are energized — not stressed — by being the person who owns the relationship and coordinates the work. You know how to pull in the right people, maintain quality, and keep the affiliate informed without creating noise. 

• You are broad by nature. You are as comfortable thinking through a contracts question as a promotional compliance issue or an employment matter. You do not need to be the expert in every room — but you need to know which expert to call, and you need the affiliate to trust that you have it covered. 

• You think from first principles and lead with solutions. When a business leader comes to you with a problem, your first instinct is to find the right path forward — not to explain why it is complicated. BridgeBio moves fast and the legal function needs to move with it. 

• You earn trust through presence, judgment, and reliability. Affiliate leaders should think of you the way they would think of a trusted advisor — someone who knows their business, anticipates their needs, and never leaves them wondering where things stand. 

• You are resilient, adaptable, and intellectually curious — energized by the breadth and pace of a multi-product, multi-affiliate environment, not flattened by it. 

WHO YOU ARE 

• You are genuinely motivated by the mission. You want to do legal work that matters — and at BridgeBio, it does. 

• You hold a J.D. from a nationally recognized law school and are admitted to practice law in the U.S. 

• You bring 10+ years of legal experience in pharmaceutical or biotech, with meaningful exposure to commercial operations, product launch, and cross-functional legal support — at a law firm, a company, or both. You have operated across multiple legal domains, not just one. 

• Your legal knowledge is broad and applied — commercial healthcare law, AKS, FCA, FDA promotional regulations, contracts, and the practical judgment to navigate employment, IP, and operational matters by knowing when to engage the right specialist and how to frame the issue clearly. 

• You have supported at least one commercial product launch — ideally more. You understand the pace, the cross-functional dynamics, and what it takes to give a commercial organization the legal support it needs to move at speed without cutting corners. This is a requirement, not a preference. 

• You communicate with precision and confidence across all levels — whether advising a field team, sitting in an MLR, presenting to affiliate leadership, or escalating a complex matter to senior legal counsel. People always know where you stand and why. 

• You are the lawyer people want to call, not the one they dread. You build real relationships with the teams you support — and those relationships are what make you effective. 

• Bay Area (Palo Alto or San Francisco) strongly preferred. Remote candidates with a genuine commitment to regular Bay Area travel will be considered for exceptional candidates — and relocation support is available for the right person. 

Position Overview:

We are building a best‑in‑class Field Medical organization as a natural next step in the growth of our Medical Affairs organization at Beam therapeutics! This Director (or Associate Director) level MSL will own a defined US territory with primary responsibility in sickle cell disease (SCD) and shared accountability across the Beam pipeline, including Alpha‑1 antitrypsin deficiency (Alpha‑1) and glycogen storage disease 1a (GSD). You will architect territory strategy, onboard priority treatment centers, engage KOLs and HCPs, generate actionable insights, and drive pre‑commercial launch readiness in close collaboration with cross‑functional partners.

Responsibilities:

• Develop and execute territory strategy: map treatment centers, referral networks, transplant/infusion sites, cell-collection capabilities, payers, and advocacy groups; prioritize accounts and set measurable objectives.
• Support treatment center onboarding: coordinate scientific and operational readiness aligned with SOPs, compliance, and patient journey requirements; partner with internal teams for qualification and activation.
• Build trusted relationships with KOLs and HCPs: deliver fair-balanced, evidence-based education on rare diseases, cell and gene therapy science, and Beam’s platform; foster advocacy and awareness.
• Educate stakeholders on disease state, therapeutic landscape, and company platform to drive awareness and credibility in the rare disease and CGT space.
• Generate high-quality insights from field interactions: synthesize trends and communicate actionable recommendations to Medical Affairs leadership and cross-functional partners.
• Collaborate on pre-launch planning: align with Medical Strategy, Publications, Medical Information, Value & Evidence, and Medical Operations to ensure scientific messaging, data dissemination, and field tools are ready for first commercial launch.
• Support clinical research activities: identify potential sites, assist with feasibility assessments, and promote best practices for enrollment and retention while maintaining medical/scientific independence.
• Partner cross-functionally with Commercial, Market Access, and Clinical teams while preserving medical independence; coordinate account plans to ensure seamless patient access and avoid duplication.
• Represent the company at congresses and external scientific meetings: plan and execute presence, engage in meaningful scientific exchanges, and follow up to strengthen visibility and credibility.
• Provide education and resources to treatment centers on operational readiness for advanced therapies, including apheresis and cell-handling processes.
• Serve as a trusted resource for compliance and ethical standards: ensure all interactions and materials meet company policies, regulatory requirements, and industry codes.
• Maintain operational excellence: document activities and insights in CRM, monitor KPIs, and continuously improve processes, content, and tools.
• Prepare and deliver training for internal teams and external stakeholders on rare disease management and CGT fundamentals to support launch readiness.
• Act as a scientific ambassador for the company: articulate the value of the platform and pipeline to diverse audiences including clinicians, researchers, and advocacy groups.
• Monitor evolving evidence and competitive landscape in rare disease and CGT; share updates internally to inform strategy and decision-making.

Qualifications:

• Advanced scientific degree (PharmD, PhD, MD, or equivalent).
• ~10+ years industry experience in Medical Affairs with significant Field Medical tenure.
• Rare disease expertise required; hematology strongly preferred with emphasis on SCD.
• Small biotech experience preferred; demonstrated impact in resource‑constrained settings.
• Launch experience (pre‑approval to post‑launch), ideally in CGT or complex specialty (buy‑and‑bill) environments.
• Proven territory management and account planning capability across complex ecosystems (academic centers, community networks, payers, advocacy).
• Independent, proactive operator with strong ownership;
• Cross‑functional collaboration with Clinical, Regulatory, Commercial, Medical Operations, and Publications while maintaining medical/scientific integrity.
• Outstanding communication skills; ability to translate complex science into clear, credible narratives.
• Analytical strength for insight collection, synthesis, and actionable recommendations.
• Travel up to ~60% across assigned territory.
• #LI-Remote

The Position

At Maze Therapeutics, we believe precision medicine has the power to transform the lives of patients with both common and rare diseases. As a Machine Learning Application Engineer II, you will play a hands‑on role in delivering high‑impact, production‑grade solutions that advance our drug discovery programs. You will design, build, and scale data and machine learning infrastructure across early research, lead optimization, and development stages of the drug discovery pipeline. In this role, you will enable data‑driven science while upholding strong engineering standards and FAIR data principles. 

This position reports to a Senior Data Engineer. 

The Impact You’ll Have

• Support management of biobank scale datasets in Polaris, Maze’s internal platform supporting Compass, by building scalable data ingestion, cleaning, processing, and validation pipelines. 
• Work with scientific compute teams to design and deploy machine learning models to support workflows in research and small molecule drug discovery (compound property prediction, assay data prediction, data analysis). 
• Lead the evaluation and integration of Large Language Models (LLMs) to automate data ingestion workflows, enhance intelligent querying, and support user-facing variant association and scientific visualization platforms. 
• Design and operate scalable ML and data platforms leveraging Terraform (IaC) and Git-based CI/CD pipelines, incorporating workflow orchestration, automated model lifecycle management, and production-grade monitoring and reliability. 
• Collaborate with development organization to evaluate and deploy ML tools that support workflows across Regulatory, Clinical Operations, and Medical Affairs. 
• Collaborate cross-functionally translate scientific requirements into production-grade systems. 

What We’re Looking For

• Master’s degree in Computer Science, Machine Learning, Bioinformatics, Data Engineering, or related fields. 
• 3+ years of industry experience building production-grade data and ML pipelines, preferably in life sciences supporting drug discovery. 
• Hands-on experience deploying AI/ML models in drug discovery applications (e.g., computational biology/chemistry workflows). 
• Experience with FAIR data principles and strong programming skills in Python and SQL (R is a plus). 
• Proven experience in deploying and maintaining ML systems, including CI/CD, workflow orchestration, and monitoring. 
• Experience with workflow orchestration tools (e.g., Airflow, Prefect). 
• Experience with containerization and cloud infrastructure (Docker, Kubernetes, AWS or similar). 

About Maze Therapeutics

Maze Therapeutics is a clinical-stage biopharmaceutical company harnessing the power of human genetics to develop novel, small molecule precision medicines for patients living with renal, cardiovascular and related metabolic diseases, including obesity. The company is advancing a pipeline using its Compass platform, which allows it to identify and characterize genetic variants in disease and then link those variants to the biological pathways that drive disease in specific patient groups through a process it refers to as variant functionalization. The company’s pipeline is led by two wholly owned lead programs, MZE829 and MZE782, each of which represents a novel precision medicine-based approach for chronic kidney disease.  Maze is based in South San Francisco.

Our People

Maze is comprised of a team of passionate and creative professionals committed to discovering and delivering transformative medicines to patients suffering from both rare and common genetic diseases. We are fostering a culture that encourages vision, initiative and the development of talent. Our supportive work environment inspires creative thinking and freedom of expression, resulting in a stimulating atmosphere where people enjoy coming to work. While we have a passion for advanced science and pride ourselves on excellence in execution, ultimately, everything we do is about patients. 

Our Core Values

Further Together – Our path is paved with challenges, but with resilience and a team-first mentality, we’ll achieve our mission. 

Impact Obsessed – We embrace the bold, take calculated risks, and learn from our mistakes to improve the lives of others.

Stand True – Our integrity is foundational; it guides us no matter the obstacle.

The expected annual salary range for employees located in the San Francisco Bay Area is $154,000 - $188,000. Additionally, this position is eligible for an annual performance bonus.

Maze performs position-based compensation benchmarking to industry market data to ensure we pay competitive wages. Determination of starting salary will depend upon a variety of job-related factors, which may include professional experience, skills, and job location. The expected salary range for this role may be modified in the future.

Maze offers a robust benefits package to our eligible employees including competitive medical, dental, and vision insurance, mental health offerings, equity incentive plan, 401(k) program with employer match and a generous holiday and PTO policy.

#LI-Hybrid

We are seeking an exceptionally motivated individual to provide leadership and support to global regulatory activities to achieve Alumis’ strategic vision in obtaining worldwide approvals to market our products. The individual will represent Regulatory Affairs and work closely with cross-functional study teams and technical regulatory service providers in accordance with health authority and ICH requirements. In addition to being a key member of our project teams, she/he will provide organizational support as the company and its product development pipeline grow. This role will be reporting to the Director of Regulatory Strategy.

ESSENTIAL DUTIES & RESPONSIBILITIES

· Serve as the Regulatory Affairs representative for Phase 1 to Phase3 trials, ensuring regulatory activities are evaluated, prioritized and executed to meet global regulatory requirements.

· Serve as the Regulatory Affairs representative on assigned study teams and assure the progress of studies by addressing regulatory related queries in support of regulatory approvals.

· Lead preparation, review and submission of INDs/CTAs, amendments, review and approval of investigator document packages and manage other regulatory activities of the assigned studies as needed.

· Establish and meet timelines for regulatory submissions related to INDs/CTAs, including nonclinical, clinical, and CMC activities, while planning for Phase 1 to 3 trials.

· Interact with Contract Research Organization (CRO) Regulatory Affairs counterpart.

· Maintain awareness of current regulatory requirements and communicate requirements in support of regulatory approvals.

EDUCATION/EXPERIENCE/SKILLS:

· Bachelor’s or advanced degree in scientific discipline, with a minimum of 5 years of experience working in drug development in the biopharmaceutical industry and at least 3 years of experience in Regulatory Affairs; immunology or rare disease/ orphan drug development experience desirable.

Knowledge/Skills/Abilities:

· Direct experience with pharmaceutical global regulatory submissions and contributing to major regulatory filing(s) such as IND/CTA.

· Working knowledge of FDA regulations and practices and ICH guidance as well as strong knowledge of global health authority regulations and practices.

· Demonstrated experience in successfully leading assigned activities within cross-functional teams.

· Excellent verbal and written communication skills.

· Collaborative, analytical and interpretative skills that enable review and compilation of reports and other documents used in regulatory planning and submissions.

· Ability to work with minimal supervision, to set priorities to meet timelines, to motivate and influence others, prior management experience a plus.

· Responsibilities may require a work schedule that may include working outside of “normal” work hours, to meet business demands.

The salary range for this position is $165,000 USD to $195,000 USD annually paid hourly per contract. This salary range is an estimate, and the actual salary may vary based on the Company’s compensation practices.

Alumis Inc. is a precision medicines company with the mission to transform the lives of patients with autoimmune diseases. Even with treatment innovations of the last two decades, many patients with immunologic conditions continue to suffer - our goal is to fundamentally change the outcomes for these patients. 

The Director, Field Medical Excellence and Training will be responsible for overseeing and advancing key field-based initiatives that inform or support Medical Affairs strategies, and developing and executing a comprehensive medical training programs across therapeutic areas. The role demands an individual who combines experience in a fast-paced environment with scientific knowledge, excellence in field medical execution, and strong educational and operational leadership.

Key Responsibilities:

· Strategic Leadership:

· Lead and drive the development, implementation, and measurement of the effectiveness of field-based initiatives to inform or support launch and new product strategies.

· Assist with development and implement frameworks for field effectiveness, including KPIs, activity metrics, and qualitative impact measures.

· Support field medical launch readiness (territory design, targeting, resource planning)

· Training & Capabilities:

· Partner with Medical Training to identify capability gaps and support ongoing development of the field medical team

· Create tools and resources to improve field execution (e.g., engagement guides, scientific narratives)

· Fostering a team culture of accountability and develop a proactive approach to growing skillsets

· Medical Insights: Collaborate with Medical Affairs Leadership to develop and drive strategies to collect, analyze, and integrate valuable medical insights that inform strategic decisions.

· Field Resources: Assess field resources to ensure a high standard of tactical execution aligned with Medical Strategy.

· Cross-functional Collaboration: Collaborate with other functional areas such as Clinical Development, Commercial, Compliance and Regulatory to ensure alignment and integration of medical excellence within the broader organizational strategy.

Qualifications:

· Education: Advanced degree in life sciences (PhD, PharmD, masters or equivalent); degree or certificate in training or education a plus

· Experience: Minimum of 7+ years of Medical Affairs expereince, including 5 yrs in Field Medical. Proven experience in training Field Medical personnel and managing field-based initiatives.

· Leadership Skills: Must have track record of effectively leading without authority, a strong commitment to teamwork, coaching or mentoring, and emotional intelligence.

· Operational Expertise: Strong experience in utilizing systems to educate and manage field-based initiatives.

· Strategic Thinking: Ability to develop and implement strategic initiatives that drive organizational goals and enhance the impact of Medical Affairs functions.

· Strong Communication: Excellent communication and interpersonal skills, with the ability to engage and influence internal stakeholders at all levels.

Primarily US remote field-based with travel.

~25% travel required to professional conferences, internal meetings, and field co-rides, including some weekends

The salary range for this position is $220,00 to 265,000 USD annually. This salary range is an estimate, and the actual salary may vary based on the Company’s compensation practices degree and background.

Alumis Inc. is an equal opportunity employer.

Alumis compensation packages include generous stock option grants for all employees as well as an annual bonus program.  

Other benefits include:

• Health insurance premiums paid at 90% for employee, 80% for dependents
• Free access to Genentech Bus & Ferry Share program
• $100 monthly cell phone stipend
• Unlimited PTO for Exempt employees
• Free onsite gym and a kitchen stocked with yummy snacks and drinks!

We are a hard-working, collaborative team on a mission to transform patient’s lives-- and we aspire to elevate, challenge and nurture one another along the way.

About the role

Anthropic is scaling internationally at speed and navigating an increasingly complex landscape of data residency requirements, sovereign AI expectations, and product localization needs. 

As International Readiness Lead, you’ll drive the cross-functional work that makes Claude deployable, compliant, and commercially viable in Anthropic’s priority markets — from compute infrastructure and data residency to product localization and sovereign deployment frameworks. 

Responsibilities

• Contribute to Anthropic’s international compute strategy in partnership with technical compute, security, and finance teams — covering cloud capacity, regional deployment models, and the path from 3P-only to 1P infrastructure in priority markets
• Develop Anthropic’s framework for evaluating and sequencing data residency and sovereign deployment requests — balancing commercial opportunity, regulatory requirements, geopolitical risk, and mission alignment
• Identify and document international customer requirements for product localization (language, compliance, data handling, integrations) and build internal processes to get them prioritized with Product and Engineering
• Translate infrastructure and product capabilities into commercial propositions — partnering with Sales and Marketing to ensure international enterprise and government customers understand what Anthropic can deliver, and when
• Serve as the internal subject matter expert on international readiness requirements, advising on deals, partnerships, and policy positions as they arise
• Build scalable processes for capturing, triaging, and acting on international product feedback so it doesn’t get lost in HQ product cycles
• Serve as the GTM strategist for Anthropic’s mission-oriented international programs — including our approach to responsible AI deployment in democratic allied nations and our strategy for expanding access and affordability in Global South markets
• Partner with Policy, Beneficial Deployments, and Global Affairs to ensure mission programs have a viable commercial and infrastructure foundation, not just a policy framework
• Track and synthesize the competitive landscape for sovereign AI and national AI programs (OpenAI for Countries, DeepMind national partnerships, Nvidia sovereign business) — surfacing implications for Anthropic’s positioning and commercial strategy

You may be a good fit if you have

• 5–7 years in product, technical GTM, solutions engineering, or strategy roles with meaningful international scope
• Strong working knowledge of cloud infrastructure, data residency frameworks, and enterprise compliance requirements — you don’t need to be an engineer, but you need to earn credibility in technical rooms
• Experience working with or selling to government customers or regulated enterprises — understanding procurement, trust requirements, and the longer sales cycles they entail
• Ability to synthesize complex technical, regulatory, and geopolitical constraints into clear commercial and strategic recommendations
• Comfortable building internal processes from scratch; this role involves significant cross-functional coordination with no existing playbook
• High autonomy and strong written communication; you’ll be influencing product, compute, and policy roadmaps without direct authority

Strong candidates may also have

• Direct experience with sovereign cloud programs, regulated data environments, or government AI initiatives
• Familiarity with EU AI Act, India DPDP Act, or similar regulatory frameworks shaping enterprise AI deployment internationally
• Experience at a hyperscaler, cloud provider, or enterprise SaaS company navigating international infrastructure decisions
• An interest in the intersection of AI, democratic governance, and responsible technology deployment — and a view on why it matters commercially, not just philosophically

What You'll Do

BridgeBio is seeking a highly strategic and execution-oriented HEOR leader to define and drive the global evidence strategy for acoramidis in ATTR-CM. This individual will play a pivotal role in enabling successful global launch, optimizing payer access, and sustaining long-term product differentiation in an increasingly competitive and evolving landscape.

As the global HEOR lead, this role will shape the evidence generation agenda across the product lifecycle—spanning clinical development, launch, and post-marketing—leveraging real-world evidence (RWE), comparative effectiveness research, and patient-centered outcomes. The leader will serve as a key partner to Market Access, Medical Affairs, Clinical Development, and Commercial teams to ensure evidence translates into impactful value narratives for payers and HTA bodies worldwide.

Why This Role Matters

Acoramidis represents a transformative opportunity in ATTR-CM. This role is central to articulating and proving its value to patients, providers, and payers globally. By shaping the evidence strategy and driving impactful insights, this leader will directly influence access, adoption, and long-term success in a competitive and rapidly evolving therapeutic area.

Key Responsibilities

• Global HEOR Strategy: Define and lead the end-to-end global HEOR strategy for acoramidis across launch and lifecycle, ensuring alignment with clinical, regulatory, and commercial objectives and driving evidence-based decision-making

• Evidence Generation & Data Strategy: Design and oversee innovative real-world evidence (RWE), economic models, and data partnerships (e.g., claims, EHR, observational survey datasets) to support value demonstration and long-term evidence generation

• Payer & HTA Readiness: Develop robust, payer-relevant evidence packages and lead HEOR contributions to global HTA submissions, pricing, reimbursement, and access strategies

• Publications & Scientific Dissemination: Lead the HEOR publication strategy, including congress planning and peer-reviewed publications with Pubs teams, to establish a compelling and credible evidence narrative

• Patient-Centered Outcomes: Drive the development and integration of PROs and other patient-centered endpoints to demonstrate meaningful clinical benefit and differentiation

• Competitive Intelligence & Positioning: Proactively assess and anticipate competitive dynamics (including generics, pipeline entrants, and alternative therapies) to inform evidence strategy and positioning

• Cross-Functional Leadership: Partner closely with Market Access, Medical Affairs, Clinical, Regulatory, and Commercial teams to ensure cohesive and actionable evidence strategies

• Governance & Scientific Integrity: Ensure HEOR activities are conducted with scientific rigor and appropriate governance, maintaining independence of evidence generation while enabling compliant, impactful use

• External Engagement: Oversee external vendors, research partners, and academic collaborations to deliver high-quality, timely evidence outputs

Where You'll Work

This is a onsite role and requires in-office collaboration 2-3x per week in our San Francisco and Palo Alto Offices.

Who You Are

• Advanced degree (PhD, PharmD, MPH, MD, or equivalent) in health economics, outcomes research, epidemiology, or related field

• 10+ years of progressive HEOR experience within biopharma or consulting, including leadership of global programs

• Demonstrated experience supporting product launches and payer strategy development in specialty or rare diseases preferred

• Strong understanding of global HTA frameworks (e.g., NICE, ICER, CADTH, G-BA) and payer evidence requirements

• Proven track record in RWE, economic modeling, and PRO strategy development

Key Competencies

• Strategic, enterprise-level thinker with strong business acumen

• Ability to translate complex evidence into clear, compelling value narratives for diverse stakeholders

• Influential cross-functional leader with a collaborative and proactive mindset

• Strong project leadership and ability to manage multiple priorities in a fast-paced environment

• Executive presence with excellent communication and stakeholder engagement skills

#LI-LN1

Job overview:  

The Regional Sales Director is a first-line sales leadership role responsible for building, developing, and leading a high-performing specialty sales team supporting the launch and growth of an innovative mental health therapy. This leader will drive regional execution of commercial strategy by partnering with certified treatment centers, psychiatrists, and integrated care systems while ensuring alignment with regulatory, safety, and patient-access frameworks. The Regional Sales Director will play a critical role in shaping a new therapeutic category, and creating a culture of integrity, collaboration, and patient-centricity.

Location: Remote in Pacific Northwest (San Francisco, CA, Seattle, WA, Portland, OR).

Reports to: Director, National Sales.

Roles and responsibilities 
(Include but are not limited to): 

• Recruit, onboard, and lead a team of Territory Account Managers
• Foster a high-accountability, psychologically safe culture that promotes coaching, development, and collaboration
• Set clear expectations and performance standards aligned with company launch objectives
• Drive successful regional execution of the commercial launch strategy and identify opportunities to expand the treatment ecosystem
• Ensure field readiness around clinical data, patient identification, treatment protocols, and site-of-care logistics
• Foster strategic relationships with psychiatrists, treatment centers, behavioral health systems, academic centers, and Key Opinion Leaders (KOLs)
• Partner cross-functionally with Medical Affairs, Market Access, Training, Patient Support, etc.
• Provide field insights to inform brand strategy and launch optimization
• Analyze regional performance metrics and develop action plans to drive results
• Manage regional budgets, forecasting, and territory alignment
• Conduct regular field coaching to strengthen clinical selling skills and consultative engagement with mental health providers

Candidate Profile:

• Bachelor’s degree required (advanced degree preferred)
• 8-10+ years of pharmaceutical or biotech sales experience
• 5+ years of first-line sales leadership experience
• Demonstrated success launching specialty or neuroscience therapies
• Experience in psychiatry, CNS, or behavioral health markets
• Experience launching therapies requiring site certification, REMS, or specialized administration models and/or a background working with IDNs, academic medical centers, and specialty treatment sites
• Experience building teams in startup or pre-launch biotech environments

What You'll Do 

The Vice President, Regulatory Affairs will oversee BridgeBio’s Operations and Labeling  functions, and will also support regulatory strategy as needed. This leader will manage a team of subject matter experts and leaders responsible for Regulatory Operations, Regulatory Business Operations, and Labeling, ensuring excellence, compliance, and strategic alignment across all regulatory activities.

The VP will ensure the organization has the right infrastructure, technology, and governance to support global submissions, and compliant labeling, while integrating advanced capabilities such as artificial intelligence to drive efficiency and insight.

The ideal candidate brings previous broad global regulatory expertise spanning for both development and commercial products, labeling, and operations, combined with understanding and experience in regulatory affairs, and the ability to lead in a fast-paced, entrepreneurial environment. #LI-TC1

Responsibilities

Strategic & Functional Leadership

• Provide overarching leadership and strategic direction for the Regulatory Operations, Regulatory Business Operations, and Labeling, each led by experienced subject matter experts and team leaders

• Partner with the Chief Regulatory Officer and Regulatory Leaders to ensure alignment of operational strategy with regulatory goals

• Foster an infrastructure that enables  innovation, speed, and accountability within and across the regulatory organization

• Lead the integration of artificial intelligence and advanced digital tools across systems and processes to enhance productivity, compliance, and decision-making

• Establish and maintain the framework for regulatory SOPs, work instructions, and desk procedures to ensure consistency, compliance, and clarity

• Lead and develop a team of team leaders and subject matter experts, fostering a collaborative and high-performance culture

• Ensure effective resource planning, talent development, and staff augmentation as needed to support corporate priorities

• Promote continuous learning and professional development within the broader regulatory organization

Where You'll Work

This is a hybrid role based either in San Francisco, or Washington, D.C. Remote will also be considered.

Who You Are

• Advanced degree in a scientific discipline (PharmD, PhD, MD, or MS) required.

• 15+ years of progressive regulatory experience in the biopharmaceutical industry, including leadership of multidisciplinary regulatory teams.

• Proven experience in labeling strategy and operations for development and commercial products, with deep understanding of global submission requirements and post-approval obligations.

• Demonstrated expertise in establishing and managing regulatory systems (e.g., Veeva Vault, RIM) and process governance frameworks (SOPs, WIs, desk procedures).

• Strong working knowledge of clinical and nonclinical regulatory strategy and interactions with global health authorities.

• Track record of leading or enabling digital transformation or AI integration within regulatory or adjacent functions.

• Exceptional leadership, communication, and influencing skills, with the ability to operate effectively in a matrixed, fast-paced environment.

• You have demonstrated curiosity and adaptability in adopting AI-powered tools and technologies.

Rewarding Those Who Make the Mission Possible

We have high expectations for our team members. We make sure those working hard for patients are rewarded and cared for in return. 

Financial Benefits:

• Market leading compensation 

• 401K with 100% employer match on first 3% & 50% on the next 2%

• Employee stock purchase program

• Pre-tax commuter benefits

• Referral program with $2,500 award for hired referrals

Health & Wellbeing:

• Comprehensive health care with 100% premiums covered - no cost to you and dependents

• Mental health support via Spring Health (6 therapy sessions & 6 coaching sessions)

• Hybrid work model - employees have the autonomy in where and how they do their work 

• Unlimited flexible paid time off - take the time that you need

• Paid parental leave - 4 months for birthing parents & 2 months for non-birthing parents

• Flex spending accounts & company-provided group term life & disability 

• Subsidized lunch via Forkable on days worked from our office

Skill Development & Career Paths:

• People are part of our growth and success story - from discovery to active drug trials and FDA pipelines, there are endless opportunities for skill development and internal mobility

• We provide career pathing through regular feedback, continuous education and professional development programs via LinkedIn Learning, LifeLabs, Spring Health & BetterUp Coaching

• We celebrate strong performance with financial rewards, peer-to-peer recognition, and growth opportunities

What You'll Do

You will be responsible for the oversight of drug product formulation and manufacturing process development and manufacturing at contract manufacturing organizations while facilitating clinical drug product disposition. You will also work with colleagues in CMC, Supply Chain Operations, Quality Assurance, and CMC-regulatory Affairs, while serving as an important point of technical contact between Calcilytix and contract research and manufacturing organizations.

Responsibilities

• Formulation composition and manufacturing process development (experience with modified/extended release is a plus)
• Person-in-plant oversight of the clinical and commercial drug product manufacturing process at CMOs (especially for small molecule solid oral dosage forms)
• Perform activities related to batch review & release, deviations, change controls, investigations and other quality related work
• Participate & provide input to root-cause analysis and CAPA plans
• Author/update regulatory filings

Where You'll Work

This is a hybrid role and requires in-office collaboration 2-3x per week in our San Francisco Office. Fully remote could be considered for the right candidate.

Who You Are

• BS degree in Life Sciences, Engineering, or related field required, advanced degrees preferred
• · Minimum of twelve (12) years of relevant experience within the pharmaceutical industry required
• · Solid understanding of CMC manufacturing and analytical activities required in commercial drug product manufacturing, including knowledge of cGMP regulations.
• · Experience with cGMP quality oversight and on floor production support required
• · Understanding of Quality Management Systems required
• · Prior experience as a liaison with solid oral dosage form contract manufacturing organizations required
• · Experience with polymer characterization (rheology, DSC, TGA), dissolution, extrusion/spraying operations, and enteric coating preferred
• · Ability to periodically travel (up to 30% at times)

#LI-NT1

What You'll Do

The Associate Director of Biomarker Science will be leading assay development, validation, and translational biomarker strategies across BridgeBio affiliate programs. This role requires a hands-on scientific leader who can design and validate assays, integrate biomarkers into clinical development, manage vendor partnerships, and communicate results to internal and external stakeholders. The successful candidate will operate at the intersection of discovery, preclinical development and clinical operations- providing scientific leadership and operational rigor to accelerate program decision-making. This position includes supervisory responsibilities: you will both lead scientific work and manage a team of scientists and technical staff, providing coaching, career development, resource planning and performance management.

Responsibilities

Discovery & Biology Strategy

• Define the biology strategy to support target validation, mechanism-of-action studies, and medicinal chemistry optimization
• Design and execute in vitro and in vivo experiments that demonstrate target engagement, functional pharmacology and disease-relevant biology to inform med chem SAR and lead optimization
• Coordinate with medicinal chemistry, structural biology and pharmacology teams to prioritize compounds, define target product profiles, and support lead selection
• Translate discovery findings into criteria and experimental plans that feed into IND-enabling studies and inform go/no-go decision points

Assay Development and Validation:

• Lead design, development and validation of biomarker and pharmacodynamic assays (cell-based, biochemical, ELISA/multiplex immunoassays, Western blotting, biophysical protein characterization, etc.) to support translational and clinical programs
• Set assay performance criteria and qualification/validation plans; author SOPs and validation reports; implement QA/QC practices to ensure reproducible assay performance

Clinical Trial Support:

• Translate preclinical biomarker findings into clinical biomarker strategies and practical assay deployment plans
• Collaborate with clinical operations, sample management and biostatistics to design sample collection, processing, storage and chain-of-custody procedures
•  Oversee incorporation of biomarker testing into Phase 1–3 protocols, including sample handling, endpoint definitions and analysis plans

Vendor Management:

• Identify, qualify and manage relationships with external vendors, CROs and CLIA laboratories for assay development, transfer and routine execution
• Lead vendor qualification, technology transfer, assay bridging and vendor audits to ensure regulatory readiness and data quality

Regulatory Compliance and Filings:

• Ensure biomarker assays and data collection comply with applicable regulatory standards (GCP/GLP where applicable)
• Contribute clinical assay sections and assay validation summaries for regulatory submissions (INDs, briefing packages, NDAs) and support responses to regulatory questions

Data Management and Analysis:

• Partner with biostatistics to develop statistical analysis plans, define analytical endpoints and produce tables, listings and figures for decision-making and regulatory documents
• Oversee rigorous data capture, QC and reporting for clinical biomarker datasets and preclinical/clinical study reports
• Contribute to statistical analysis plans and the design of tables, listings, and figures

Scientific Communication & Leadership

• Prepare and present scientific reports, publications and conference abstracts; engage with key opinion leaders to inform biomarker strategy
• Present translational data to program teams and senior leadership; mentor and develop early-career scientists
• Support internal initiatives to capture lessons learned, propagate best practices and continuously improve biomarker workflows
• Collaborate with drug discovery, clinical development, and regulatory affairs teams to integrate biomarker strategies
• Present data to the broader MLBio team, including scientific, clinical, and business leaders

Where You'll Work

This role involves primarily hands-on laboratory responsibilities in our San Carlos, CA location.

Who You Are

• Minimum Education requirement:
• M.S. or Ph.D. in Biology, Biochemistry, Molecular Biology or a related discipline.

Relevant Experience

• Minimum 10 years of industry experience in translational science, biomarker development, or related roles supporting clinical development.
• Demonstrated track record developing and validating cell-based and biochemical assays for clinical use; experience with ELISA, multiplex immunoassays, Western blotting and protein characterization methods.
• Hands-on experience with assay transfer to CRO labs, vendor qualification, and supporting regulatory filings.
• Strong understanding of clinical study design, GCP, and regulatory expectations for biomarker data.
• Experience writing scientific and regulatory documents and collaborating with cross-functional teams including biostatistics.

Skills & Attributes

• Strong scientific judgment and experimental design skills; ability to interpret complex datasets and provide clear, actionable recommendations.
• Excellent written and oral communication; experience presenting to scientific and business audiences.
• Proven leadership and mentorship skills; collaborative, proactive and team-oriented approach.
• Detail-oriented with strong project management abilities and a commitment to high quality data and documentation.

Travel

• Travel for vendor management/audits and scientific meetings as required.

Mavericks Wanted 

When was the last time you achieved the impossible? If that thought feels overwhelming, you might want to pause here, but if it sparks excitement...read on 
  
In 2015, we pioneered a “Moneyball for biotech” approach, pooling projects and promising early-stage research from academia together under one financial umbrella to reduce risk and unleash innovation. This model allows science and small teams of experts to lead the way. We build bridges to groundbreaking advancements in rare conditions and develop life-changing medicines for people with unmet needs as fast as humanly possible.  
  
Together we define white space, push boundaries, and empower people to solve problems. If you're someone who defies convention, join us and work alongside some of the most respected minds in the industry. Together, we'll ask, "why not?" and help reengineer the future of biopharma. At BridgeBio, we value curiosity and experimentation—including the ethical & thoughtful use of AI to improve clarity, speed, and quality of work. 

What You'll Do

The Associate Director, Achondroplasia Community Marketing, will support the development and commercialization of a key asset, infigratinib. The Associate Director, Achondroplasia Community Marketing, will drive cross-functional collaboration and tactical alignment, ensuring success in the US. This individual will lead the development and execution of tactics supporting people living with achondroplasia for the commercial launch of infigratinib. This person will occupy an important role on commercial product teams, work closely with Market Insights, Market Access, Regulatory, Medical Affairs, and other key stakeholders to deliver integrated commercial planning and execution. The Associate Director, Achondroplasia Community Marketing, should feel at home in a fast-paced, ambiguous environment. This position requires excellent communication, organization, and collaboration skills. The Associate Director, Achondroplasia Community Marketing, will report to the Senior Director of Marketing.

Responsibilities

• Serve as a commercial member on the Product Teams, embedding the market needs into cross functional planning

• Drive innovative tactics and address untapped opportunities

• Lead achondroplasia community brand planning, messaging and claims work

• Identify and develop community members for ambassador programming

• Uncover and address unmet community needs by seeking insights to improve/refine launch planning and execution

• Lead agile, cross-functional team to develop/launch innovative achondroplasia community marketing campaigns that will inspire change and drive brand growth; ensure aligned launch execution across functions

• Develop and track metrics to measure and ensure the success of marketing/promotional programs

• Coordinate with digital marketing to build an effective customer engagement ecosystem

• Partner with Value and Access to develop programming to support community access

• Partner with regional teams to ensure diverse commercial insights are brought into the planning process, be the commercial voice advocating for these views

• Partner closely with advocacy teams to develop tactics that will help educate and support people living with achondroplasia

• Work cross-functionally with agency partners, sales, commercial operations, brand analytics, IT, MCM, etc.

Where You'll Work

This is a hybrid role and requires in-office collaboration 3x per week in our San Francisco or Palo Alto Office.

Who You Are

• 5+ years of commercial biotech or pharmaceutical experience, with at least three years in Marketing

• Successful launch experience in a competitive market is preferred

• Rare disease experience preferred

• Demonstrated ability to develop and action insights from complex clinical data and market research

• Understanding of the drug development process, especially regarding opportunities for differentiation and value demonstration

• Excellent oral, written, and presentation skills

• Passionate about serving people living with Genetic conditions

• Proven self-starter, able to work independently and as part of a team

• Able to handle full workload across multiple projects

• Collaborates seamlessly across functions to build effective working relationships and align strategy and execution.

• High level of self-awareness and understanding of the importance of self-monitoring behavior for continuous improvement

• True entrepreneurial spirit – BridgeBio was built to do things differently and address the needs of underserved populations, driven by science and unrelenting passion for people living with genetic conditions

• Ability to travel (~20%) is required

• You have demonstrated curiosity and adaptability in adopting AI-powered tools and technologies

Rewarding Those Who Make the Mission Possible

We have high expectations for our team members. We make sure those working hard for the communities we serve are rewarded and cared for in return. 

Financial Benefits:

• Market leading compensation 

• 401K with 100% employer match on first 3% & 50% on the next 2%

• Employee stock purchase program

• Pre-tax commuter benefits

• Referral program with $2,500 award for hired referrals

Health & Wellbeing:

• Comprehensive health care with 100% premiums covered - no cost to you and dependents

• Mental health support via Spring Health (6 therapy sessions & 6 coaching sessions)

• Unlimited flexible paid time off - take the time that you need

• Paid parental leave - 4 months for birthing parents & 2 months for non-birthing parents

• Flex spending accounts & company-provided group term life & disability 

• Subsidized lunch via Forkable on days worked from our office

Skill Development & Career Paths:

• People are part of our growth and success story - from discovery to active drug trials and FDA pipelines, there are endless opportunities for skill development and internal mobility

• We provide career pathing through regular feedback, continuous education and professional development programs via LinkedIn Learning, LifeLabs, Spring Health & BetterUp Coaching

• We celebrate strong performance with financial rewards, peer-to-peer recognition, and growth opportunities

At BridgeBio, we strive to provide a market-competitive total rewards package, including base pay, an annual performance bonus, company equity, and generous health benefits. Below is the anticipated salary range for candidates for this role who will work in California. The final salary offered to a successful candidate will depend on several factors that may include but are not limited to the type and length of experience within the job, type, and length of experience within the industry, educational background, location of residence and performance during the interview process. BridgeBio is a multi-state employer, and this salary range may not reflect positions based in other states.

What You'll Do

Maverick wanted! We’re seeking a Director of Patient Identification Programs responsible for designing, operationalizing, leading, and scaling enterprise-wide patient identification strategies that enable timely diagnosis, and access to approved therapies. This role sits at the intersection of commercial strategy, data science, medical affairs, clinical development, and external partnerships, and plays a critical role in accelerating patient journeys towards diagnosis and treatment.

The Director will design, build, and manage a portfolio of innovative patient identification initiatives, leveraging real-world data, diagnostic pathways, digital tools, and healthcare ecosystem partnerships to identify, educate, and connect eligible patients to appropriate genetic testing, clinical programs, or treatments.

Responsibilities

Strategy & Leadership

• Develop and execute a comprehensive patient identification strategy aligned with commercial launch and pipeline priorities, disease areas, and corporate objectives.
• Serve as the enterprise subject-matter expert on patient identification, diagnostic pathways, and unmet diagnostic needs.
• Lead and mentor cross-functional contributors to patient identification programs.

Program Design & Execution

• Design and operationalize patient identification programs focused on (pre-)commercial stage and – to a lesser extent – clinical stage programs.
• Leverage initiatives such as diagnostic algorithms, EHR-based identification, biomarker screening, genetic testing programs, and referral pathways.
• Ensure programs are scalable, compliant, and adaptable across geographies and indications.

Cross-Functional Collaboration

• Partner closely with Commercial, Medical Affairs, Data Science, Market Access, Regulatory, Legal/Compliance, Clinical Development teams
• Align patient identification efforts with launch readiness plans
• Provide strategic input into evidence generation and disease education initiatives

Data & Analytics

• Leverage real-world data (claims, EHR, genomics, registries) to identify patient populations and optimize identification approaches
• Define success metrics, dashboards, and KPIs to measure program impact and inform continuous improvement
• Translate data insights into actionable recommendations for internal stakeholders

External Partnerships

• Build and manage relationships with diagnostic companies, health systems, laboratories, advocacy groups, digital health vendors, and data partners
• Evaluate and onboard innovative technologies and vendors to enhance patient identification capabilities
• Represent the company externally as a thought leader in patient identification and rare disease diagnosis

Governance & Compliance

• Ensure all programs adhere to applicable regulatory, privacy, and compliance requirements (e.g., HIPAA, GDPR, promotional regulations)
• Partner with Legal and Compliance to design ethical, patient-centric programs that prioritize trust and transparency

Who You Are

• Advanced degree (PhD, MD, PharmD, MPH, MS) or equivalent experience in life sciences, healthcare, or a related field
• 8–12+ years of experience in biopharma, healthcare, diagnostics, or health technology, with significant experience in patient identification and related functions
• Proven experience designing, building, and operating complex, cross-functional programs and influencing senior stakeholders
• Strong understanding of diagnostic pathways, rare disease ecosystems, and real-world data sources
• You have demonstrated curiosity and adaptability in adopting AI-powered tools and technologies

Preferred

• Experience in rare disease, precision medicine, or genetically defined conditions
• Familiarity with digital health tools, advanced analytics, and AI-enabled identification approaches
• Experience working with external partners and vendors in a highly regulated environment

Key Competencies

• Strategic thinking and execution excellence
• Strong leadership and stakeholder influence
• Data-driven decision making
• Comfort with ambiguity in fast-moving, early-stage environments
• Patient-centric mindset and high ethical standards

Why This Role Matters

This role directly impacts patients by reducing time to diagnosis, expanding access to innovative therapies, and ensuring that no eligible patient is overlooked. The Director of Patient Identification Programs is a critical driver of both scientific and human outcomes.

Where You'll Work

3x per week in our San Francisco Office/Palo Alto Office

Company Overview

BridgeBio is a biopharmaceutical company founded to discover, create, test, and deliver transformative medicines to treat patients who suffer from genetic diseases and cancers with clear genetic drivers. We bridge the gap between remarkable advancements in genetic science in academic institutions and the delivery of meaningful medicines to patients. Founded in 2015, the company has built a portfolio of 20+ drug development programs ranging from preclinical to late-stage development in multiple therapeutic areas including genetic dermatology, precision oncology, cardiology, endocrinology, neurology, pulmonology, and renal disease, with two approved drugs.

Our focus on scientific excellence and rapid execution aims to translate today’s discoveries into tomorrow’s medicines. We have U.S. offices in San Francisco, Palo Alto, and Raleigh, with small satellites in other parts of the country. We also have international offices in Montreal, Canada, and Zurich, Switzerland, and are expanding across Europe.

To learn more about our story and company culture, visit us at bridgebio.com.

What You’ll Do

The Director / Senior Director, Quality Assurance is responsible for managing and overseeing the Good Pharmacovigilance Practices (GVP) quality and compliance program at Eidos Therapeutics and other assigned BridgeBio affiliate companies. It requires strong judgement skills and business acumen in order to advise internal and external key stakeholders on interpretation and compliance with FDA, EMA, MHRA and international pharmacovigilance (PV) regulations/guidelines; corporate policies; and standard operating procedures (SOPs). This individual will be a lead point of contact in the preparation and management of GVP regulatory inspection activities.

 Responsibilities

• Provide strategic and operational guidance to the organization, including, drug safety/pharmacovigilance, medical affairs, regulatory, commercial, clinical operations and outsourcing functions, to align with company procedures, regulatory requirements and best practice

• Support the internal and external GVP audit program

  • Oversee audit schedule and the execution of the audit program

  • Lead or co-lead auditor on PV audits as needed

  • Review and/or approval of audit reports and corrective and preventive action (CAPA) responses

• Maintain and contribute of audit and quality data for the Pharmacovigilance System Master File (PSMF)

• Core GVP regulatory inspection team member

  • Lead or participate in inspection readiness activities

  • Host or support of regulatory inspections

  • Perform quality review of inspection requests

  • Oversee the development and tracking of regulatory responses/commitments

• Review of Quality Agreements and PV/Safety Data Exchange Agreements (PVA/SDEA) to assess quality standards and regulatory compliance requirements

• Participate in the investigation and assessment of PV/GxP-related quality events and provide input on proposed CAPAs

• Develop, generate and present PV quality/compliance metrics for trending and process improvement

• Provide quality oversight on PV-related computer system validation projects and maintenance of systems

• Collaborate with Eidos and BridgeBio affiliate companies to develop and continuously improve processes and systems, including policies, SOPs and training plans

• Partner cross-functionally to support the business with compliance or quality issues/concerns by ensuring appropriate evaluation, mitigation and escalation to Executive Management

• Keep abreast of changes in regulations and enforcement actions and make recommendations for changes to policies and practices as needed

Where You’ll Work 

This is a hybrid role and will require in-office collaboration in our San Francisco Office. 

Who You Are

• Bachelor’s degree with 10-15+ years of GVP quality and compliance experience within a biopharmaceutical company, or contract research organization

• Current knowledge of global GVP regulations and guidelines – US Code of Federal Regulations, EMA, MHRA, and ICH Guidelines

• Ability to engage in cross-functional interactions with internal and external staff

• Has a comprehensive understanding of current approaches in industry and the ability to incorporate them into Eidos and BridgeBio affiliate programs

• Applies strong analytical and business communication skills

Mavericks Wanted

When was the last time you achieved the impossible? If that thought feels overwhelming, you might want to pause here, but if it sparks excitement...read on
 
In 2015, we pioneered a “moneyball for biotech” approach, pooling projects and promising early-stage research from academia together under one financial umbrella to reduce risk and unleash innovation. This model allows science and small teams of experts to lead the way. We build bridges to groundbreaking advancements in rare disease, and develop life-changing medicines for patients with unmet needs as fast as humanly possible. 
 
Together we define white space, push boundaries and empower people to solve problems. If you're someone who defies convention, join us and work alongside some of the most respected minds in the industry. Together, we'll ask "why not?" and help reengineer the future of biopharma.

What You'll Do

At BridgeBio, legal support must match the urgency and importance of the medicines we bring to patients. In this role, you will primarily support the commercial legal needs of ATTRUBY, BridgeBio’s leading commercial product and one of the company’s most important brands, while also providing support across select affiliate matters as needed. Your work will be focused on the core legal processes that help the business operate effectively and compliantly, including Material Review Committee (MLR) review, contract review, and grants review support. Working closely with Commercial, Medical, Regulatory, Compliance, and other cross-functional partners, you will help the business move with clarity, consistency, and speed while supporting one of BridgeBio’s highest-priority commercial efforts.

Responsibilities

·       Participate as a member of the MLR, collaborating with Medical Affairs, Regulatory, and Compliance to help ensure promotional and scientific materials are accurate, balanced, and compliant.

·       Review, draft, and negotiate a range of commercial agreements, including vendor, services, confidentiality, consulting, and other business agreements, using approved templates and playbooks where appropriate.

·       Support legal review of grants and related funding requests, including coordination with internal stakeholders to assess risk, consistency, documentation, and compliance with applicable policies and requirements.

·       Provide practical, day-to-day legal guidance to internal clients in support of ATTRUBY and other business priorities across the full scope of activities —commercial strategy, HCP and HCO engagement, promotional materials, patient programs, payer and market access, and contracts.

·       Track relevant legal and regulatory developments affecting promotional review, grants, and commercial contracting, and help translate those developments into practical guidance for the business.

Where You'll Work

Bay Area preferred; Remote with Bay Area travel considered

Who You Are

·       J.D. degree from a nationally recognized law school and admitted to practice law in the United States.

·       Approximately 5+ years of relevant legal experience at a law firm, pharmaceutical, biotech, or med-tech company, and/or government agency.

·       Experience supporting legal review in one or more of the following areas: promotional review, commercial contracting, grants, healthcare compliance, medical affairs support, or broader life sciences commercial counseling; prior promotional review committee experience strongly preferred.

·       Familiarity with legal frameworks relevant to the life sciences industry, which may include FDA promotional requirements, fraud and abuse laws, transparency laws, OIG guidance, and industry codes.

·       Strong drafting, issue-spotting, and organizational skills, with the ability to manage multiple matters efficiently.

·       Professional maturity, sound judgment, and the ability to build trusted working relationships with internal clients and colleagues.

·       A high degree of ethics, integrity, and accountability.

Rewarding Those Who Make the Mission Possible

We have high expectations for our team members. We make sure those working hard for patients are rewarded and cared for in return. 

Financial Benefits:

• Market leading compensation 

• 401K with 100% employer match on first 3% & 50% on the next 2%

• Employee stock purchase program

• Pre-tax commuter benefits

• Referral program with $2,500 award for hired referrals

Health & Wellbeing:

• Comprehensive health care with 100% premiums covered - no cost to you and dependents

• Mental health support via Spring Health (6 therapy sessions & 6 coaching sessions)

• Hybrid work model - employees have the autonomy in where and how they do their work 

• Unlimited flexible paid time off - take the time that you need

• Paid parental leave - 4 months for birthing parents & 2 months for non-birthing parents

• Flex spending accounts & company-provided group term life & disability 

• Subsidized lunch via Forkable on days worked from our office

Skill Development & Career Paths:

• People are part of our growth and success story - from discovery to active drug trials and FDA pipelines, there are endless opportunities for skill development and internal mobility

• We provide career pathing through regular feedback, continuous education and professional development programs via LinkedIn Learning, LifeLabs, Spring Health & BetterUp Coaching

• We celebrate strong performance with financial rewards, peer-to-peer recognition, and growth opportunities

Company: 

At Annexon Biosciences we are a biopharmaceutical company advancing a late-stage clinical platform of novel therapies for people living with devastating classical complement-mediated neuroinflammatory diseases of the body, brain, and eye. Our novel scientific approach targets upstream C1q to block the classical complement inflammatory cascade before it starts, and its therapeutic candidates are designed to provide meaningful benefits across multiple autoimmune, neurodegenerative and ophthalmic diseases. With proof-of concept data in Guillain-Barré syndrome, Huntington’s disease and geographic atrophy, we are rigorously advancing our mid-to late-stage clinical trials to bring new potential treatments to patients as quickly as possible. At Annexon, you’ll be part of a team committed to making an impact together.   

For more information on Annexon and our pipeline, check out our site Annexon Biosciences & Annexon Pipeline. We trade on Nasdaq under the ticker symbol ANNX and are headquartered in Brisbane, CA. 

We're seeking exceptional talent from all backgrounds to fuel our growth. At Annexon, we're building a diverse, equitable, and inclusive workplace. We value unique perspectives and unconventional paths. If you're the best candidate for the job, even if you don't perfectly fit the traditional mold, we encourage you to apply. Learn more about our commitment to diversity, equity, inclusion, and our company culture! 

Position: 

The Field Medical Directors (FMDs) are medical experts who are an extension of the Medical Affairs team and represent Annexon with key stakeholders. They engage with national, regional, and local scientific, clinical, and social thought leaders (TLs) at academic and community medical centers as the scientific and medical expert on Annexon’s products and areas of research. This role will develop and maintain professional relationships with TLs based on scientific exchange of disease and Annexon product data. 

Responsibilities include: 

• Develop and maintain professional relationships with Thought Leaders (TLs) through compliant scientific exchange via two-way communication inclusive but not limited to pathogenesis of Therapeutic Areas (TA) of interest to Annexon, diagnosis, disease burden, treatment landscape, health economics, and relevant Annexon product data in line with medical affairs and Annexon strategy
• Collaborate with TLs on research projects, national and regional advisory boards, visiting professorships, publications, and peer-to-peer educational initiatives
• Develop and maintain the highest scientific and medical expertise in ophthalmologic disease, trials and treatment landscape with a patient centric mindset
• Identify potential high-impact medical research projects, investigator-initiated research, health-economic trials, and publication opportunities in line with Annexon TAs of interest
• Be acknowledged internally and externally as a trusted Scientific expert and build lasting professional relationships with TLs and Centers of Excellence & Research (COERs)
• Attend local, regional, national, international meetings and congresses as needed to engage in Scientific exchange, capture scientific insights, share data on Annexon products and TAs, and identify areas for collaboration with TLs
• Respond to healthcare professionals (HCPs) with integrity, a sense of urgency, adherence to all laws, regulations, and Annexon guidelines, policies & procedures
• Partner with Patient Advocacy Organizations in a compliant manner to integrate the patient voice into scientific and medical communications
• Deliver education on Annexon’s science and product data to P&T committees, formulary decision makers, and local, regional and national payers in accordance with all laws, regulations, and Annexon’s guidelines, policies, and procedures, while aligning with medical affairs and Annexon’s overall strategy
• Develop and execute tailored TL and HCP scientific engagement plans as needed
• Engage with TLs, trial investigators, and research staff, to support Clinical Development and Clinical Operations activities including but not restricted to identification of viable study sites, facilitation of participation in clinical trials, and patient recruitment
• Ensure strong, compliant collaboration with cross-functional field partners
• Serve as the Medical Expert and a field representative for Medical Directors with TLs, investigators, and other cross-functional partners

Education, Experience, and Skills: 

Required: 

• Scientific, healthcare or medical degree (PharmD, PhD, MD, DO)
• FMD requires 4 to 6 years of field-based experience in biopharmaceutical industry in medical affairs or relevant clinical roles and FMSD requires 6+ years of experience
• Prior experience as a Medical Science Liaison within Ophthalmology, with demonstrated expertise in retinal or ocular diseases and established relationships with key opinion leaders (KOLs) in the space.
• Scientific and patient-centric mindset with a successful track record of delivering results exceeding objectives in support of medical affairs and Annexon strategies
• Strong communication and presentation skills as evidenced by the ability to rapidly analyze complex scientific and medical data and synthesize for effective communication to audiences with diverse backgrounds
• Demonstrated ability to build scientific relationships with TLs, clinicians, researchers, and other relevant internal or external stakeholders
• Able to effectively collaborate within a matrix organization and cross functional teams
• Solid knowledge of the healthcare landscape inclusive but not limited to hospital systems, various points of care, and the roles of relevant HCPs in the target TAs
• Solid knowledge of the drug development process, and the role of various internal and external stakeholders in various phases of R&D
• Able to document insights, TL engagement and complete all administrative tasks in a timely fashion
• Capable of working independently to prioritize tasks, develop and implement action plans, and make sound, compliant decisions
• Strong understanding of compliance, and the legal and regulatory landscape as they relate to HCP interactions
• Flexible to travel within assigned region based on business needs and occasionally nationally or internationally

Location: Central Plains Region / Remote Field Based (includes onsite travel to Annexon – HQ) 

Level: This role may be filled at the Associate Director or Director level, depending on the candidate’s experience and qualifications 

Salary Range: ($190,000 - $224,000)