About the Role >>> Senior Director, International Finance and Operations 

The Senior Director, International Finance & Operations will lead the establishment and ongoing finance operations of the Company’s Ireland entity. This role is responsible for building finance infrastructure, ensuring compliance with Irish and EU requirements, and supporting integration with global financial systems. 

Reporting to the VP of Finance, this individual will serve as a key execution partner in delivering the Company’s international expansion into Ireland, a critical strategic priority. This role will work cross-functionally with internal stakeholders and external advisors to drive timely, coordinated execution across all aspects of the entity build-out and ongoing operations, including but not limited to finance operations, indirect tax compliance, and local governance. 

This role is based out of our Dublin, Ireland office and will require 10% travel. 

Your role will primarily encompass: 

Ireland Entity Setup & Execution  

• Lead execution of the Ireland entity build-out in coordination with internal teams and external partners  
• Drive implementation of cross-functional workplans, ensuring alignment with key milestones and timelines 
• Manage interdependencies across Finance, Legal, HR, IT, and external advisors 
• Develop and maintain project plans, timelines, and key milestones  
• Track progress against deliverables, proactively identify risks or delays, and drive resolution with Finance leadership  
• Indirect Tax & VAT Compliance 
• Oversee VAT registration and ongoing indirect tax compliance in Ireland/EU  
• Coordinate with external advisors on VAT filings and regulatory requirements  
• Ensure timely and accurate preparation and submission of VAT returns  
• Establish and maintain documentation, processes, and controls to support compliance and audit readiness  
• Identify and escalate tax-related risks and technical issues and process gaps 

Finance Operations & Infrastructure 

• Lead the establishment and oversight of finance operations for the Ireland entity, including payroll, local compliance, and financial processes  
• Oversee payroll setup and ongoing coordination with HR and external providers  
• Ensure payroll and related processes are accurate, compliant, and timely  
• Support integration of the Ireland entity into global financial systems, reporting, and internal controls  
• Implement global finance policies in alignment with local regulatory requirements  

Stakeholder Management & Cross-Functional Execution 

• Act as a central point of coordination across cross-functional stakeholders and external partners to support execution of Ireland-related activities  
• Drive alignment, clarity, and accountability across teams 
• Lead cross-functional meetings, track decisions, and ensure follow-through on key action items  
• Provide regular updates to Finance leadership on status, risks, and timelines  

Finance Processes & Controls 

• Establish and document finance processes and internal controls for a new entity  
• Support development of scalable processes as operations grow  
• Ensure alignment with U.S. reporting requirements and internal control frameworks, including SOX readiness, to ensure transition from setup to steady-state operations 

Additional Responsibilities 

• Support additional finance, tax, and operational initiatives as needed  
• Assist in preparation of materials for leadership review and decision-making 
• Act as a key execution partner to the VP of Finance in delivering the Ireland expansion initiative 
• Support prioritization, issue resolution, and cross-functional alignment across workstreams  

Ideal Candidate Profile  

A love of challenging, important work. We are a pragmatic team, driven to imagine and develop meaningful therapies for improving lives. All employees within our company play a unique and crucial role in our success, both in accomplishing our mission and building a positive company culture. As such, we are looking for someone with the right combination of knowledge, experience, and attributes for this role. 

Knowledge: 

• Bachelor’s Degree in Finance, Accounting, or related field (required) 
• CPA, ACA, ACCA, or equivalent (required) 
• Strong understanding of finance operations, accounting principles, and internal controls 
•  Familiarity with indirect tax/VAT in Ireland and/or EU 
• Knowledge of SOX compliance and public company financial environments (preferred) 

Experience: 

• Minimum of 12+ years of experience in finance, accounting, or related roles 
• Minimum of 3+ years in leading and managing teams 
• Experience in biotech, pharma, or life sciences (required)  
• Experience supporting international operations and/or entity setup 
• Experience working with external advisors (e.g., tax, payroll, legal) 
• Strong project management experience across cross-functional initiatives 
• Experience building or scaling finance processes and controls 
• Experience supporting integration into financial systems and reporting structures 
• Exposure to indirect tax/VAT compliance and filings 
• Experience in a SOX-compliant or public company environment (required)

Additional Attributes: 

• Strong project management and organizational skills 
• Ability to operate in a fast-paced, evolving environment 
• Strong communication and stakeholder management skills 
• Execution-oriented mindset  

#LI-MK1

Powering the Future of Biotech Finance

Are you ready to play a key role in managing financial strategies for an innovative, fast-growing biotech company? As a Treasury Analyst at Legend Biotech, you'll have a unique opportunity to work at the heart of our global Treasury operations in Dublin, Ireland. Your work will directly support cash management, forecasting, and reporting, all while contributing to our mission of revolutionizing cancer treatment.

What can you expect?

• Financial Strategy & Cash Management: Prepare cash forecasts, intercompany funding, and FX projections, helping optimize liquidity and manage foreign exchange risks across the business. Your work will play a crucial part in the financial health of the company.
• Reporting & Executive Support: Produce detailed management reports on cash performance, cash management targets, and long-term planning. Work closely with Treasury leadership to provide insights and prepare executive-level presentations for key stakeholders.
• Operational Efficiency: Support day-to-day Treasury operations, including opening/closing bank accounts, administering online banking systems, and managing corporate card and travel accounts. Your organizational skills will help maintain smooth financial operations.
• Compliance & Process Improvement: Ensure all processes align with regulatory standards and participate in audit reviews and process walkthroughs. You’ll also contribute to continuous improvements in Treasury processes, optimizing efficiency and enhancing controls.
• Collaboration & Innovation: Work with cross-functional teams and be involved in projects that support both short-term and long-term business goals. Your teamwork will help drive operational excellence and innovation in the finance space.

Who are we looking for?

Education 

• Bachelor’s in Accounting or Finance 

Experience

• A minimum of 3 years of progressive Treasury experience
• Experience in a Global environment

Expertise

• Professional certifications such as ACT/IACT, CPA/CMA/ACCA/CIMA are a plus
• Knowledge of SOX financial controls on Accounting and reporting processes is preferred
• Experience with ERP systems (SAP preferred)

Language

• Fluent in English with excellent written and verbal communication skill

Strengths

• Collaborative and proactive, with the ability to manage multiple priorities
• Strong communication skills to work with all levels of the organization
• Excellent at financial modelling, forecasting, and reporting
• Highly organized with a keen eye for detail and process improvement
• Proficient in Excel, PowerPoint, and business reporting tools (Onestream preferred)

What do we offer you?

A fixed term contract of 9 months duration with a competitive salary package complemented by a range of fringe benefits.
Work in a supportive and innovative environment at our Dublin office, where we encourage learning and personal development.
Join a fast-growing, global company with a unique blend of start-up culture and financial stability, combining the cutting-edge biotech space with the financial assurance of a Nasdaq-listed company.

About Legend Biotech

Legend Biotech is a global leader in biotechnology, focused on developing, manufacturing, and commercializing life-saving cell therapies to treat chronic and life-threatening diseases like cancer. Founded in 2014, we are headquartered in Somerset, New Jersey, with over 2,400 employees across six global manufacturing sites. We’re committed to making a real difference in patients' lives worldwide.

About Us

Qualio is a unified quality and compliance management platform that helps regulated organizations get products to market faster with reduced risk. Trusted by biopharma, medtech, and diagnostics companies worldwide, Qualio eliminates fragmented systems that create audit delays and compliance blind spots. Our platform enables audit readiness in weeks through multi-standard automated gap analysis and evidence reuse across ISO and FDA requirements. Qualio is ISO 27001, ISO 9001, and ISO 27701 certified, reflecting our commitment to security, quality, and privacy.

The Qualio team is all-remote, and currently distributed across North America, Europe and Australia.

What’s the opportunity?

We have a fantastic opportunity for a Product Manager to join our dynamic, collaborative and remote-first Qualio team!

Join Qualio as a pivotal player in a high-velocity cross-functional product development team. Help us transform an industry that, literally, saves millions of lives every year. This is challenging but incredibly rewarding work being done with a supportive and passionate team. 

Product at Qualio

• We take a cross-disciplinary approach at every level. Product Management, Design and Engineering (EPD) all report into our VP, EPD and consider themselves part of one team.
• Everything a customer experiences is part of our product, whether it is delivered by technology or a human. We strive to be a product-led company. 
• All members of EPD have an outsized influence but also an expectation of ownership for overall customer and company outcomes
• We are open and collaborative by default (e.g. public slack channels, lots of collaborative work in open documents, minimal organizational hierarchy, etc.)
• We are dedicated to continuously improving our craft at product development. We reflect on and evolve our own practices and concepts regularly. We engage with the industry to make sure we are at the top of our game. We guarantee that you will be a much better professional for having worked with us.
• All members of EPD are makers more than managers. Product Managers make clarity and confidence out of ambiguity and uncertainty. That means more than 75% or more of your time will be spent generating insights, proposals, decisions, user stories, outcome-focused communications, etc. rather than organizing meetings, schedules, etc.

What will I be doing?

• Refine and deeply understand customer problems — synthesising existing feedback, customer interviews, and usage data into clear problem definitions and confident solution proposals.
• Lead solution design in close collaboration with Engineering, from early concepts through to shipped products.
• Demonstrate compelling and confident storytelling that surfaces assumptions and difficult decisions but also aligns stakeholders around solutions. A large portion of your job is inspiring and driving work.
• Work within a supported structure alongside a Staff Product Manager, taking ownership of problems and driving them through solution design and delivery across different product areas as the team's needs evolve.
• Grow into taking on broader problem spaces and contributing to roadmap planning across product areas — balancing near-term customer pain relief with longer-term strategic solutions.
• Work collaboratively across EPD, and with key partners in Customer Success, Support, Marketing, and Sales

What skills do I need?

• 3-5 years of experience as a Product Manager in a B2B SaaS environment – experience or strong interest in highly-regulated industries, life-science, or "service design" (i.e. technology-powered and human-powered aspects working together) preferred.
• A passion for delivering effective and elegant products and services that solve customer problems, especially high-quality UX and solid platform architectures
• Ability to engage directly with customers for discovery interviews, user research, feedback collection, and validation of product concepts and prototypes
• Strong product design skills with ability to create wireframes, user flows, and work collaboratively on design solutions that solve customer problems
• An approachable and collaborative working style with a rigorous mindset and eagerness to learn and grow
• Experience planning and managing successful launch and adoption of work, not just building and deploying it.
• Fluent in working in agile development environments – we aren't ideological about process but we are definitely not waterfall.
• Experience with AI – understanding of AI/ML capabilities and limitations, experience integrating AI features into products, familiarity with AI tools and workflows, and ability to communicate AI value propositions to stakeholders
• Preferred experience with product analytics – proficiency with analytics tools (e.g., Pendo, Datadog, Quicksight), ability to set up tracking and measurement frameworks, experience analyzing user behavior data to inform product decisions.
• Preferred experience in a medical device, SaMD, or other highly regulated industry (e.g. pharma, biotech) 

Benefits

In addition to playing an important role in building Qualio, you'll receive:

• Competitive salary
• Flexible holidays
• Unlimited Time Off
• Professional development stipend
• Working space allowance / home office budget
• Opportunity to make a difference through helping life-saving products to get to market

A note to candidates:

Studies have shown that women and people of color are less likely to apply for jobs unless they believe they meet every single one of the qualifications as described in a job description. We are committed to building a diverse and inclusive company and we are most interested in finding the BEST candidate for the job. That candidate may be one who comes from a less traditional background, and that’s okay. We would strongly encourage you to apply, even if you don't believe you meet every one of the qualifications described.

Job purpose

The role will provide structured assistance across document management, complaints handling, reporting, and general administrative activities. Securing this support will improve operational efficiency, strengthen compliance, and enable QA professionals to focus on high-value quality and oversight responsibilities. The Quality Department operates in a highly regulated environment with increasing demands related to documentation, customer assurance, and quality reporting. QA administrative workload has grown significantly, particularly in areas such as complaints management, CMO scorecard development, and compliance checks.

Responsibilities

The Quality Associate support will initially provide approximately 20 hours per week of support across the following key areas

• Document Creation and Execution Support

• Preparation, formatting, and maintenance of QA documentation within Veeva
• Coordination of document lifecycle activities including review and version control
• Ensuring adherence to internal documentation standards

• Complaints Management Support

• Initiating and tracking of customer complaints
• Supporting data entry, documentation, and follow-up activities
• Assisting in maintaining audit-ready complaint records

• CMO Scorecard Development

• Supporting data collection and consolidation for CMO performance metrics
• Assisting in the preparation and formatting of scorecards and reports
• Maintaining consistency and accuracy in reporting outputs

• Distribution and Quality Disposition Support

• Coordinating distribution of quality-related documents and communications e.g. disposition returns
• Supporting quality disposition processes and maintaining executed record logs e.g Temperature excursions
• Facilitating communication between internal and external stakeholders as needed

• Bona Fide Customer Checks

• Conducting verification checks on customers
• Maintaining accurate and traceable records of compliance activities
• Supporting QA in meeting regulatory and internal compliance requirements

• General Administrative Support (Ad Hoc)

• Event and meeting organization
• Additional administrative duties as required

Qualifications

Required Qualifications

• Bachelor’s degree in Life Sciences, Biotechnology, Chemistry, Engineering, or a related scientific discipline
• Approximately 5 years of hands-on experience in a life sciences Quality environment (biotech, pharmaceutical, medical device, or regulated healthcare industry)
• Demonstrated experience supporting Quality Assurance (QA) and Quality Management System (QMS) activities
• Strong working knowledge of GxP requirements (e.g., GMP, GDP) and regulated documentation practices
• Proven experience with document creation, formatting, execution, and lifecycle management within an electronic document management system (e.g., Veeva Vault or similar)
• Experience supporting complaints management processes, including documentation, tracking, and maintenance of audit-ready records
• High attention to detail with the ability to maintain accurate, compliant, and traceable records
• Strong organizational and time management skills, with the ability to manage multiple tasks and prioritize effectively in a part-time (approximately 20 hours/week) support role
• Excellent written and verbal communication skills, with the ability to interact professionally with internal and external stakeholders
• Proficiency with Microsoft Office tools (Word, Excel, PowerPoint), particularly for data consolidation, tracking, and reporting
  
  #LI-HYBRID

Job purpose

As the Associate Director, External Manufacturing and Supply Operations, you are responsible for operational execution of external manufacturing and related supply activities. This is a central role within Manufacturing and External Supply Operations and requires the ability to manage multiple activities simultaneously, balancing priorities, with a strong sense of urgency, ability to work with ambiguity, and attention to detail. This position will have you collaborating with other members of Supply Chain, Quality Assurance, Regulatory Affairs, and Finance to execute and deliver endorsed global supply plans for both clinical and commercial supply. You will report to the Director, External Supply Operations.

Responsibilities

• Build and maintain productive relationships with external contract manufacturers (CMO’s), and internal global colleagues
• Ensure timely and effective execution of all manufacturing and supply plans at assigned CMO’s
• Develop and manage production processes to support operational execution, including BOM’s, specifications, CAPA’s, change controls, master data, and artwork. Familiarity with ERP/MRP systems
• Support logistics, transportation and import/export activities
• Act as the manufacturing and supply chain representative for review and approval of documentation including but not limited to batch records, BOM’s, specifications, artwork, and change control
• Support product qualification activities including but not limited to reviewing/approving IQ/OQ/PQs, stability, and validation protocols; review and approve change controls
• Play a key role in supporting selection and onboarding of new CMOs, technical transfers, operationalizing product supply and site establishment
• Manage and track inventory, perform inventory reconciliations, and support month end close process.
• Issue purchase orders, and track invoices and budgets
• Maintain production schedules and track batch record execution in coordination with Quality
• Oversee, review, and approve as necessary revisions to manufacturing cGMP and non GMP documentation
• Proven risk management acumen with a continuous improvement mindset
• Where necessary, provide input to the manufacturer and QA for evaluation of process deviations and assist in the investigation of product complaints
• Build and maintain strong partnerships and provide effective communication with all internal and external stakeholders and lead discussion, problem solving efforts and process improvements to ensure that performance targets are met or exceeded
• Responsible for scheduling and maintaining routine business operations meetings with CMO’s
• Support Regulatory submissions and CMC as required

Qualifications

Education & Core Experience

• BS/BA Degree in Life Science, Biology, or Engineering discipline from an accredited college or university, or equivalent desired
• 10+ years’ combined experience in manufacturing, outsourced operations, technical operations and/or supply chain in regulated healthcare industry, preferably within biotech/pharmaceutical industry
• cGMP career experience embedded in a pharmaceutical manufacturing plant is essential – with first-hand knowledge of plant operations, with the insight to assess performance, and diagnose issues directly at the source
• Technical background with knowledge of engineering and pharmaceutical manufacturing processes in small molecules is required, and experience in DS/API production is desirable
• Excellent problem-solving skills, with the ability to address complex challenges under time pressure
• Demonstrated expertise in risk management, with a history of successfully implementing risk mitigation strategies
• Hands-on investigations/RCA (OOS/OOT/deviations) and continuous improvement at external sites
• The ability to function in a fast-paced, high-growth, entrepreneurial environment
• Ability to travel domestically and internationally ~25%
• Position requires a strong working knowledge and understanding of both regional and international regulations by government agencies affecting the pharmaceutical industry (CFR's, EU GMP, ICH)
• Timely and effective communication across multiple audiences, both verbally and in writing
  
  #LI-HYBRID

As Associate Director, Sourcing & Supplier Relationship Management, you will play a critical role in ensuring the suppliers and partners we work with meet our high standards for quality, innovation, and patient impact. This role plays a critical part in the comprehensive lifecycle of Cytokinetics relations with partners and suppliers supporting Global Supply Chain & Technical Operations. This role requires strong strategic thinking, broad industry experience and excellent relationship development and management skills. This role will support our Sourcing and Network Strategy pillar, a key component of our Global Supply Chain & Technical Operations strategy.  This role will support our Manufacturing and Lab Services Supplier Strategy, marketplace assessments of supplier capabilities from early development thru post approval Commercialization, supplier due diligence through Request for Information (RFI) and Requests for Proposals (RPF). These due diligence activities will lead to collaborative supplier selection, contract negotiations, operationalization of the relationship and ultimately management of supplier performance against the contract. This role will be a key partner to CMC and Technical Operations, External Manufacturing and Supply Operations, Enterprise Risk Management, Supply Planning and Partner Pillar activities, and the Supply Chain Center of Excellence in Dublin Ireland. This role requires demonstrated business acumen, influencing skills, strategic thinking, relationship building and collaboration behaviors.

Responsibilities

Strategic Supplier Management

• Develop and execute sourcing and network strategies that align with Global Supply Chain & Technical Operations goals.
• Serve as the primary commercial point of contact for assigned CMOs, Labs and critical suppliers.
• Conduct marketplace assessments, supplier segmentation, and due diligence (RFIs/RFPs).
• Collaborate with Enterprise Risk Management to identify and mitigate supplier sourcing risks.

Contracting & Negotiations

• Lead supplier selection, contract negotiations, and agreement development in partnership with Legal, Finance, Procurement, and Quality.
• Support External Supply team with contract setup, budget planning, and tracking.

Performance & Risk Management

• Monitor supplier performance using standard KPIs and ensure compliance with contractual and regulatory requirements.
• Support supplier audits and develop business continuity and risk management processes.
• Identify opportunities to improve supplier value, cost, quality, and service.

Collaboration & Leadership

• Partner with CMC, Technical Operations, Supply Planning, and global teams in Dublin, Ireland.
• Represent Supply Chain Sourcing on cross-functional teams for complex projects.

Our employees come from different backgrounds, and we celebrate those differences. We are looking for the best candidates for our open roles, but do not expect applicants to meet every qualification in order to be considered. If you are excited about what you could accomplish at Cytokinetics and believe you can add value to our team, we would love to hear from you.

Qualifications

• Bachelor’s degree in Biology, Chemistry, Engineering, or related field (advanced degree a plus).
• 10+ years of experience in Life Sciences, Engineering, Business, or Supply Chain, preferably within Biotech/Pharma.
• Strong understanding of product development, GMP manufacturing, and related regulations (cGMP, GCP, CFRs, Part 11, FDA/EMA Guidelines).
• Proven expertise in manufacturing cost benchmarks and pricing strategies for small molecule manufacturing.
• Demonstrated success in supplier relationship management, contract negotiation, and strategic sourcing.
• Strong communication, collaboration, and influencing skills.
• ERP systems experience, preferably Oracle
• Ability to travel domestically and internationally (15–20%).

#LI-HYBRID

Our passion is anchored in robust scientific thinking, grounded in integrity and critical thinking. We keep the patient front and center in all we do –all actions and decisions are in service of the patient and their caregivers. We champion integrity, ethics, doing the right thing, and being our best selves.

Please visit our website at: www.cytokinetics.com

Cytokinetics is an Equal Opportunity Employer

We are currently seeking a Senior Manager, Supply Chain and Technical Project Management in our Global Supply Chain & Technical Operations department. 

This position is integral to the advancement of Cytokinetics’ growing portfolio of drug candidates and technology programs and will coordinate cross-functionally to ensure project deliverables are met on-time, on-budget, and with a high degree of quality.

Reporting to the Director of Portfolio Management within Global Supply Chain & Technical Operations, this role will be responsible for the creation, and management of timelines, and deliverables to support the technical development, validation, and commercialization of drug substances, formulated drug product and packaging using Cytokinetics internal resources and an external network of providers. 

Responsibilities

• Provide project management support at any stage of the drug development lifecycle (e.g., early to late-stage development, market authorization, or post-launch phases)
• Develop charters, integrated schedules, deliverable lists, status updates, resource requests and related communications for assigned projects and programs
• Maintain a positive, results-oriented work environment by building partnerships, modeling collaboration and communicating in an open, balanced and objective manner to enable a high-performing team
• Proactively monitor timelines, KPIs, critical path, and resources for assigned projects using appropriate tools, project management principles and practices to deliver project objectives
• Work cross-functionally to coordinate interdependencies with other projects. Resolve and/or escalate conflicts and issues to remove barriers to project success
• Leverage risk management tools and techniques to proactively identify, mitigate and manage risks throughout the project lifecycle to avoid deviations to the project goals and objectives
• Engage sponsors, functional senior leadership, and key stakeholders in regular and meaningful project communications (dashboards, reports, metrics, etc.) to ensure delivery of expected business outcomes
• Lead and/or support continuous improvement of processes and tools
• 10-20% Travel, as necessary according to project needs

Qualifications

• BA/BS in Scientific, Technical, Engineering or Business discipline (advanced degree preferred)
• A minimum of 10 years total work experience, with at least 5 or more years relevant experience in project management within the life sciences (pharmaceutical / biotech / medical device) industry
• Sound technical knowledge in one or more of the following categories: Chemical Development, Formulation Development, Clinical, Manufacturing, Analytical, Packaging, Serialization, Planning, or Logistics (small molecule drug development is a plus)
• Outstanding project management, planning, organization, prioritization, and time management skills
• Ability to adapt to changing situations, and effectively manage multiple projects and priorities
• Ability to think creatively in order to provide non-standard solutions
• Strong partnering skills – ability to thoughtfully cultivate strong and highly effective working relationships with internal and/or external customers and stakeholders
• Strong influencing, organizational and interpersonal skills – consistently achieves targeted results without authority by leveraging expertise, business knowledge, and partnerships
• Project Management Professional (PMP) Certification preferred
• Six Sigma or other Operational Excellence related certifications is a plus
  
  #LI-HYBRID