The Opportunity:

General Purpose 

The Senior Director, Head Pharmacist/Responsible Pharmacist guarantees the pharmaceutical responsibility of the laboratory as “exploitant” (see definition of the “exploitant”, Article R.5124-2, 3 ° of the French Public Health Code) and assumes the role of "Responsible Pharmacist" as described in Article R.5124-36 of the Public Health Code. Responsibilities include:

• Organize and supervise all pharmaceutical operations of the company or organization, including manufacturing, advertising, information, pharmacovigilance, batch monitoring and withdrawal, distribution, import and export of the drugs, products, objects or articles concerned, as well as the corresponding storage operations.

• Ensure that transport conditions guarantee the proper preservation, integrity and safety of these medicines, products, objects or articles.

• Acknowledge the files related to marketing authorization applications submitted by Corporate or organization and any other application related to the activities they organize and supervise.

• Participate in the development of research and study programs.

• Imperson authority over delegate and deputy pharmacists; approve their hiring and be consulted on their dismissal, except in the case of an army pharmacist-chemist.

• Appoint interim delegate pharmacists.

• Inform the other directors of the company or organization of any obstacle or limitation to the exercise of these powers.

• Implement all necessary means to comply with the obligations set out in articles R. 5124-48 and R. 5124-48-1;

• In the case of medicinal products intended to be marketed in the territory, he(she) ensures that the safety measures referred to in article R. 5121-138-1 have been affixed to the packaging in accordance with the conditions set out in articles R. 5121-138-1 to R. 5121-138-4;

• Notify the Agence nationale de sécurité du médicament et des produits de santé (ANSM : French National Agency for the Safety of Medicines and Health Products) of any launching on the national market of a medicinal product which is considered to be falsified within the provisions of article L. 5111-3, and for which they are responsible for the manufacture, exploitation and distribution.

They organize the quality system within the laboratory in accordance with French laws and regulations (good distribution practices, good pharmacovigilance practices, good manufacturing practices) and laboratory requirements.

They also support the transversal activities carried out by the marketing, medical, compliance and market access departments.

The Senior Director, Head Pharmacist/Responsible Pharmacist, France takes part in the deliberations of the management, administrative, executive or supervisory bodies, or those of any other body with an executive function, of the company or organization, when these deliberations concern or may affect the performance of the tasks falling under his/her responsibility as described above.

The RP is responsible for ensuring compliance with professional ethics and all regulations issued in the interests of public health. He/she must also ensure that the responsibilities of pharmacists and staff under his/her authority are clearly defined.

In accordance with articles L. 5121-14-3, R. 5121-152 and L. 5121-164 of the French Public Health Code, the RP ensures that pharmacovigilance cases are reviewed and processed within the appropriate timeframes.

In accordance with article L5121-9-2 of the French Public Health Code, the RP immediately informs the French National Agency for the Safety of Medicines and Health Products of any prohibition or restriction imposed by the competent authority of any country in which the medicinal product for human use is marketed, and of any other new information likely to influence the evaluation of the benefits and risks of the medicinal product for human use or the product concerned.

In addition, the Responsible Pharmacist also has knowledge of :

• the role of professional bodies and organizations that regulate those who supply medical products to the public.

• the ANSM's role in handling controlled drugs.

• the role of the European Medicines Agency (EMA) and the use of EUDRAGMDP.

• the Directive on Falsified Medicines.

• the principles and guidelines of good manufacturing practice, and how GMP/GDP principles maintain product quality throughout the distribution chain.

Responsibilities

In the performance of the duties, the Employee is responsible for the following tasks in French territory:

Regulatory Affairs:

• Submission and obtaining the opening authorization application for the “Exploitant” pharmaceutical establishment.

• Filling and submission of the annual facility master file (once a year).

• Relationships with the Health competent authority – the French Agency for the Safety of Medicines and Health Products (ANSM).

• Participation in the management of early access programs.

• Monitoring of drug marketing (declaration to the health authority of the date of initial marketing, reporting of prohibition or restriction decisions or any information likely to influence the benefit/risk assessment).

• Validation of the Advertising and Medical Information process.

• Participation in pharmaceutical document archiving management.

• Implementation of the Regulatory Intelligence process.

• Supervision of pharmaceutical contracts (head office and outsourced activities).

Quality Assurance/Supply Chain:

• Regular audits of internal pharmaceutical activities (distribution, medical information, promotion processes, claims, pharmacovigilance processes, etc.).

• Implementation of a risk management approach (document management, claims, audits, continuous improvement, premises, suppliers, shortages, etc.) and business continuity plan.

• Implementation of change control management process following regulatory approvals (marketing authorization, variations, risk management plan, etc.).

• Participation in audits and inspections by authorities (ANSM, etc.).

• Follow-up of batch release for distribution in France and tracking/traceability.

• Management of batch recalls with the marketing authorization holder, the health authority and distribution stakeholders.

• Management of shortages with the health authority.

• Storage and distribution management.

• Management of quality complaints.

• Implementation of procedures (SOP).

• Implementation of compliance with the French Charter of Promotional Information and its Guidance.

• Implementing quality compliance:

• Planning, execution and follow-up of audits.

• Implementation of KPIs (definition, collection and analysis of KPIs for key pharmaceutical activities).

Pharmacovigilance and drug safety management:

• Implementation of the local pharmacovigilance process.

• Nomination of local Qualified Persons responsible for Pharmacovigilance.

• Interaction with European Qualified Person responsible for Pharmacovigilance (QPPV); Global Patient Safety Department (GPS)and PV database.

• Procedures and data management.

• Report to Competent authorities.

• Collection, registration, assessment, report and follow-up of adverse events.

• Screening of local scientific and medical literature for pharmacovigilance relevant information.

• Local Signal detection.

• Review and validation of Periodic Safety Update Report (PSUR).

• Reconciliation of shared PV data.

• Implementation of key performance indicators (KPI).

• Monitoring of product good use and off-label use, and declaration to competent authorities if applicable.

Medical information management:

• Implementation of medical information process in collaboration with the Medical information department (data management, standard responses, access to literature database).

• Collection, registration and response to medical information requests.

• Reconciliation of shared medical information data.

• Implementation of KPI.

Advertising and promotional information:

Promotional and non-promotional material review and approval.

Review and submission to Health authority of promotional material.

Approval and dissemination of the positive list.

Logistical management of material with traceability (withdrawal, archiving, etc.).

Personnel training:

• Implementation of a local training process for pharmaceutical and compliance processes.

• Review and validation of training material for commercial and medical teams.

• Validation of integration and ongoing staff training plans, and monitoring of training plans.

• Ensuring that all staff are trained in Good Practices, their own tasks, product identification, risks of drug falsification and specific training for products requiring more rigorous handling.

• Competency assessment and empowerment of key personnel.

Participation to Compliance management:

• Participation to implementation of French law about anti-bribery, transparency and compliance of interaction with HCPs and HCOs.

• Participation to legal review of agreements with healthcare professionals, hospitals, organizations, etc.

Management of the Pharmaceutical Affairs Department in France

• Team leadership, development and management;

• Recruitment, training and development of team members;

• Follow-up of team objectives.

The above list of tasks is not exhaustive.

Required Skills, Experience and Education:

• Doctor in pharmacy and able to be registered as Responsible Pharmacist.

• Specialization in regulatory affairs and quality.

• Minimum 15 years of proven experience in leadership roles within the biopharmaceutical industry in the field of oncology.

• Fluency in both verbal and written French and English.

• Proven leadership and people management capabilities; demonstrated success in small but fast growing, entrepreneurial commercial environment.

• High capacity of social competence for teamwork, coaching and situational leadership.

• Proven track record shaping and executing country strategy and influencing policy at a senior industry level.

• In-depth knowledge of the French pharmaceutical market and regulatory environment.

• Ability to create and nurture a strong culture of collaboration and authenticity to extend and replicate the RevMed culture.

• Proven success in building effective relationships with internal stakeholders, regional authorities, and vendors.

• Highly organized and motivated individual possessing excellent communication, presentation and interpersonal skills.

Revolution Medicines takes protection and security of personal data very seriously and respects your right to privacy while using our website and when contacting us by email or phone. We will only collect, process and use any personal data that you provide to us in accordance with our CCPA Notice and Privacy Policy. For additional information, please contact privacy@revmed.com. 

#LI-Remote #LI-LO1

We are looking for a Senior Medical Lead to join our Medical Excellence team.

At Doctolib, we're setting a new pulse for healthcare. We create AI-powered solutions that help health professionals deliver better care, and help people be healthier. As a Medical Lead, you'll play a critical role in delivering medical innovations with direct public health impact. 

Reporting to the Chief Medical Officer, you will be responsible for the scientific and medical quality and delivery of our patient generalist health companion, particularly its AI Health Assistant. Working hand in hand with product and tech teams, you'll ensure we build medically robust software products

Your responsibilities include but are not limited to:

• Being accountable for the medical quality of the product and ensuring we build the best solutions from a scientific and medical standpoint
• Driving medical value and risk assessments to ensure the development of qualitative, safe, and reliable products, and reviewing related specifications
• Developing and validating medical features to ensure accuracy and quality, including AI model performance evaluation
• Maintaining medical features and content up to date to provide health professionals with accurate and current medical information
• Participating in the definition and implementation of the medical knowledge strategy for your product scope
• Conducting scientific and medical bibliography to ensure all content and products rely on trusted sources

Who you are

Before you read on: if you don't have the exact profile described below, but you feel this job description matches your skill set, we still encourage you to apply.

You could be our next team mate if you:

• You have at least 3-5 years of clinical experience as a medical doctor 
• You are an expert in statistics and epidemiology, and thrive with numbers and analytical work
• You have previous experience in healthtech and software development environments
• You are structured, detail-oriented, and have a strong analytical mindset with excellent project management and communication skills
• You are fluent in French and English

Now it would be fantastic if you:

• You are fluent in German or Italian
• You have a double engineer/medical doctor background
• You have a PhD in statistics or epidemiology

What we offer

• Free comprehensive health insurance for you and your children
• 25 days of paid vacation per year, plus up to 14 days of RTT
• Free mental health and coaching services through our partner Moka.care
• Work from abroad for up to 10 days per year thanks to our flexibility days policy
• Lunch vouchers (Swile card) worth €8.50 per working day, with €4.50 covered by Doctolib
• A subsidy from the work council to refund part of the membership to a sport club or a creative class
• 50% reimbursement of your public transport subscription
• Parent Care Program: receive one additional month of leave on top of the legal parental leave
• For caregivers and workers with disabilities, a package including an adaptation of the remote policy, extra days off for medical reasons, and psychological support

The interview process

• Talent Acquisition Interview
• Interview with our CMO
• Case Study 
• Final Interview
• At least one reference check
• Offer!

Job details

• Permanent position
• 80-100% FTE
• Levallois-Perret
• Start date: Asap
• Compensation: fixed + bonus on objectives (according to your profile)

At Doctolib, we are committed to improving access to healthcare for everyone. This translates into our recruitment process. We evaluate candidates based solely on qualifications and motivation, without any form of discrimination.

The more diverse ideas are heard, the more our product will truly improve healthcare for all. You are welcome to apply to Doctolib, regardless of your gender, religion, age, sexual orientation, ethnicity, disability.

To ensure equal opportunities, we invite you to exclude personal information (e.g. pictures, age) from your applications. If you require any accommodation, please let us know for support during the hiring process.

Join us in building the healthcare we all dream of!

All information provided is processed by Doctolib for application management. For data processing details, click here: France. Please contact hr.dataprivacy(at)doctolib.com for inquiries or to exercise your rights.

What you’ll do

Doctolib is looking for a medical expert to join our Medical Excellence team, and contribute to the delivery of medical innovations with a direct public health impact. Reporting to the Medical Affairs Manager, you will be responsible for ensuring the value of medical features and medical content on all our products across Europe. We work to deliver software products that are scientifically and medically robust.

Your mission

While your end mission will be to help our users deliver better care and people take better care of their health, you'll be supporting our Product & Tech teams crafting and developping the best solutions to fit their needs. Integrated in our features teams you'll be working on a specific product domain.

Your responsibilities include but are not limited to:

Functionality 

• Work hand-in-hand with our product and tech team to ensure we build the best products from a scientific and medical standpoint
• Assess the medical value and risks of medical features in our products to ensure development of qualitative, safe and reliable products and review the related specifications
• Review and validate medical features before roll-out to ensure accuracy and quality, including AI model performance when relevant
• Maintain medical features & content up to date to provide healthcare professionals with accurate up to date medical information

Content

Medical content includes (non-exhaustive list)

In product content : medical guidelines and templates (ex: prescription template, care plan explanation), decision trees or algorithms based on recommendations, for both doctors and patientsMedia & marketing content:

• Participate to the definition & implementation of the medical knowledge strategy for Doctolib products
• Review medical features & content to validate accuracy of messaging conveying medical information to healthcare professionals or patients
• Coordinate the end-to-end content creation and validation programs on your scope, including interactions with public organisations, scientific society, doctors, …

Coordination & Monitoring

• Perform scientific & medical bibliography to ensure all content & products on your scope rely on trusted sources
• Work in close collaboration with Healthcare professionals (Doctolib pioneers) as well as many teams within Doctolib (Product, Product Marketing, Marketing, …) to ensure that we provide the best medical tools to doctors & patients

Who you are

Are you convinced that you have exactly what it takes for the position? Then we encourage you to apply. Even if you don't meet every requirement, you might be exactly the right future Doctoliber for this or other positions!

You could be our next team mate if:

• You have at least 5 years of experience as a medical doctor (generalist, public health, pediatrician)
• You have previous experience in tech & software development environment
• You have a strong appetence for science and are a strong promoter of the evidence based approach, and have published scientific papers in the last 3 years
• You practice as a clinician at least 1 day/ week and are open to keeping a 1-day/ week clinical practice
• You are structured, detailed-oriented and have a strong analytical mindset
• You have strong project management skills, you are action/result-oriented and hands-on

You are product & user centric 

• You are fluent in French, and English (German and Italian are a plus)
• You recognize yourself in the values of Doctolib (Service, Care, Act, Learn)

What we offer

• Free Health Insurance for you & your children
• Quarterly bonus
• Up to 14 days of RTT 

• A flexible workplace policy offering both hybrid and office-based mode
• Flexibility days allowing to work in EU countries and the UK 10 days per year 
• Wellbeing program (free mental health and coaching offer with our partner moka.care)
• For caregivers and workers with disabilities, a package including an adaptation of the remote policy, extra days off for medical reasons, and psychological support.

• Lunch voucher with Swile card
• Work Council subsidy to refund part of sport club membership or creative class
• Bicycle subsidy
• Reimbursement of public transportation 
• Relocation support for international mobilities
• Slean voucher for home-office furniture

The interview process 

• Talent Acquisition Interview
• Hiring Manager Interview
• Case Study with two hiring managers 
• Reference check 
• Offer 

Job details

• Permanent position 
• 80 % FTE
• Workplace : Levallois-Perret
• Start date : 2026
• Remuneration : fix + bonus on objectives 

At Doctolib, we are committed to improving access to healthcare for everyone. This translates into our recruitment process. We evaluate candidates based solely on qualifications and motivation, without any form of discrimination.

The more diverse ideas are heard, the more our product will truly improve healthcare for all. You are welcome to apply to Doctolib, regardless of your gender, religion, age, sexual orientation, ethnicity, disability.

To ensure equal opportunities, we invite you to exclude personal information (e.g. pictures, age) from your applications. If you require any accommodation, please let us know for support during the hiring process. 

Join us in building the healthcare we all dream of!

All information provided is processed by Doctolib for application management. For data processing details, click here. 

Please contact hr.dataprivacy(at)doctolib.com for inquiries or to exercise your rights.