About the role

Anthropic is seeking a Policy Counsel to support our public policy and legal initiatives at the intersection of AI technology and regulation. As a member of our legal team, you'll work cross-functionally to navigate emerging policy challenges and help build and advocate for frameworks that promote responsible AI development. This is an exceptional opportunity to tackle novel legal and policy questions while contributing directly to the future of AI governance.

Responsibilities

• Support the development of AI governance frameworks that align with evolving regulations, industry best practices, and global standards Monitor and analyze emerging legislative and regulatory developments related to AI
• Provide legal analysis and advice to the External Affairs team and other Public Policy stakeholders
• Partner with Public Policy and technical teams in developing practical policy guidance that is informed by a deep understanding of our products 
• Assist in drafting policy positions and proposals and advocacy materials

Minimum qualifications

• Law degree and qualification to practice law in a relevant EMEA jurisdiction
• Experience with policy, regulatory, or government affairs work, whether in government, at a technology company, a law firm, or a policy organization
• Strong written and verbal communication skills, including the ability to make complex legal and technical concepts accessible to non-legal audiences
• Strong analytical and problem-solving skills, with the ability to work through ambiguous policy questions

Preferred qualifications

• 6+ years of relevant legal experience
• Experience working on complex technology policy issues across AI/ML policy, data privacy, copyright, or technology regulation
• Familiarity with EMEA legislative and regulatory processes, including experience with EU or national-level advocacy
• Experience drafting policy positions, comment letters, or regulatory submissions
• Demonstrated ability to quickly understand AI concepts and translate them into policy contexts
• Interest in government affairs matters and a commitment to responsible AI development
• A collaborative, humble approach and the ability to work effectively across diverse teams
• Comfort working in a fast-paced environment while maintaining attention to detail

Role-specific policy: For this role, we expect all staff to be able to work from our London or Dublin office at least 3 days a week, though we encourage you to apply even if you might need some flexibility for an interim period of time

Liquid Personnel is recruiting Social Care Worker for its client's Children's Residential Team based in Limerick, Ireland.

Our client is seeking a dedicated Social Care Worker to join a newly established service focused on providing a trauma‑informed model of care for young people aged 13 to 17. This role centres on creating a therapeutic environment built on positive relationships and healthy attachment.

As part of the care team, you will play a vital role in delivering comprehensive, trauma‑informed support. Responsibilities include direct work with young people, household tasks, administrative duties, teamwork, professional development, and ensuring consistent health and safety standards.

This is an exciting opportunity to make a meaningful impact on young people’s lives by providing supportive, therapeutic relationships and contributing to their overall wellbeing.

What will your responsibilities be?

• Develop and Implement Care Plans: Contribute to creating and recording Care and Placement Plans
• Advocate for Young People: Promote young people’s rights, needs, and responsibilities
• Ensure Welfare: Support the physical, emotional, social, and cultural wellbeing of each young person
• Encourage Participation: Support attendance at school, training, and health appointments
• Support Personal Affairs: Assist with personal documents, arrangements, and financial management
• Stakeholder Engagement: Liaise with families, carers, and relevant external agencies
• Attend Relevant Meetings: Participate in planning and review meetings
• Engage in Activities: Take part in age‑appropriate activities and play
• Physical Interventions: Carry out approved physical interventions when necessary in line with policy
• Promote Decision‑Making: Encourage young people to participate in decisions that affect them
• Meal Preparation: Plan and prepare balanced, nutritious meals with young people
• Home Management: Support the upkeep of the home, budgeting, and general household duties
• Reporting: Attend team meetings and report to the relevant team leader or manager
• Safeguarding: Follow safeguarding procedures and act as a designated safeguarding officer when required
• Stay Informed: Maintain up‑to‑date knowledge of legislation, standards, and best practice
• Professional Development: Engage in ongoing training and development opportunities
• Policy Adherence: Comply with organisational policies, procedures, and professional guidelines
• Regulatory Standards: Work in line with national residential care standards and regulatory requirements

Benefits:

• Paid maternity leave
• Family‑friendly working policies
• Employee wellbeing and assistance programme
• Flu vaccination programme
• Cycle‑to‑work scheme
• Commuter and tax‑saving schemes
• Flexible working arrangements
• Opportunities for internal mobility after a qualifying period
• Option to apply for a career break after two years of service

Extra benefits: 

• Bike to work scheme
• Company pension
• Employee assistance program
• Wellness program

Qualifications & Experience:

To be successful in this role you must have, 

• Registration (or eligibility for registration) with the appropriate professional Social Care regulatory body
• Commitment to safeguarding and promoting the welfare of young people
• Strong communication, teamwork, and relationship‑building skills
• Willingness to participate in ongoing training and development

Reasonable Adjustments:

If you consider yourself to have a disability or require any reasonable adjustment during the recruitment process or within the workplace, please highlight this at the earliest opportunity by contacting our team.

We are unable to support or accept applications from candidates who are residents within the Red or Amber list of the World Health Organisation (WHO) Workforce Support and Safeguard List.

BH - 197514
GH - 34396

About the Role >>> Sr Director, Commercial Manufacturing & Operations

As the Sr Director, Commercial Manufacturing & Operations reporting to the SVP of CMC & Supply Chain, you will be an experienced manager with a track record of successful project leadership and oversight of late-stage (registrational, process validation, commercial) manufacturing of small molecule drug substances and drug products. You will be responsible for the execution of technical transfer (including process validation activities), oversight of manufacturing activities, document review, quality event support, etc. for drug substances and drug product.

This role is based out of our Boston, USA and will require 20% travel.

Your work will primarily encompass:

· Support the US launch of palazestrant in 2027 by creating the commercial supply platform and strategy

· Establish an operational commercial mapping of supply and partners (state licenses, 3PL & order-to-cash Services, shipping and import/export logistics, import/export compliance)

· Provide technical and functional project leadership on drug substance (DS) and drug product (DP) commercial manufacturing, and CMO management

· Develop business processes and systems to support and streamline all DS and DP commercial activities. Work globally to implement processes and systems within Olema’s global CDMO network. Develop metrics and continuous improvement initiatives.

· Ensure employees are engaged and tied to the global Olema’s business strategy

· Lead or manage documentation review and approval (MBRs, specifications, analytical methods, etc.), change controls and documentation for internal batch disposition

· Oversee investigations related to deviations to assess impact to product and manufacturing process; ensures timely closure of such investigations

· Partner with Commercial, Quality Assurance and CMC Regulatory Affairs SMEs to develop and operate appropriate commercial procedures to ensure the drug substance and drug product meets established quality standards and adheres to established and regulatory agency approved parameters

· Work closely with SMEs and CMOs to execute shipment of drug substance batches and drug product lots

· Partner with supply chain teams to design DS and DP production schedules while maximizing production and cost efficiencies

· Develop, maintain and communicate product manufacturing plans, timelines, milestones and budgets. Integrate and align commercial manufacturing activities with corporate development program objectives. Develop and apply resource and capacity models

· Stay current with state-of-the art approaches and applicable global regulations and industry standards

Ideal Candidate Profile >>>

A love of challenging, important work. We are a pragmatic team, driven to imagine and develop meaningful therapies for improving lives. All employees within our company play a unique and crucial role in our success, both in accomplishing our mission and building a positive company culture. As such, we are looking for someone with the right combination of knowledge, experience, and attributes for this role.

Knowledge and experience:

· BS/MS/Ph.D. in Chemistry, or related discipline with a minimum of 10+ years of experience, or a business degree with a minimum of 15 years of experience, in a CMC development and manufacturing organization

· Sense of urgency, ability to recognize time sensitivity, appetite to lead aggressive activity within the manufacturing function

· Flexible and adaptable style, achievement oriented by nature with a willingness and eagerness to take on challenges

· Visionary as well as tactile and concrete at an operational level.

· Demonstrated successful leadership in a pharmaceutical CMC drug substance and drug product development and manufacturing role

· Broad experience working with CDMOs and managing external development and manufacturing partners

· Expertise in oversight of GMP manufacturing, including tech transfer and process validation

· Understanding of supplier performance management (quality metrics, adherence to supply and quality agreements) and familiarity with commercial supply agreement negotiations

· Thorough understanding of global regulatory requirements for the manufacture, testing, and control of commercial drug substances

· Strong communication, negotiation, problem solving and decision-making skills at all levels of the organization, verbally and in writing

· Ability to work collaboratively to connect vision, strategy and goals and present plans, justifications and mitigation scenarios to executive management

· Effective written, oral communication and interpersonal skills

Attributes:

· A high level of curiosity, intelligence, ability to work independently, “can do” attitude, and ability to work cross-functionally. Strong initiative and follow-through are essential for this job.

· Specific personal characteristics include:

o Highly analytical and detail oriented

o Self-Starter

o Goal and data driven

o Ability to multi-task and shift priorities rapidly to meet tight deadlines

o Aspires to the highest scientific and ethical standards

o Keen to improve processes and overcome inefficiencies

The base pay range for this position is expected to be $225,000 - $250,000 annually, however the base pay offered may vary depending on location, market, job related knowledge, skills and capabilities, and experience. The total compensation package for this position also includes equity, bonus, and benefits.

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#LI-MK1

Job purpose

As the Associate Director, External Manufacturing and Supply Operations, you are responsible for operational execution of external manufacturing and related supply activities. This is a central role within Manufacturing and External Supply Operations and requires the ability to manage multiple activities simultaneously, balancing priorities, with a strong sense of urgency, ability to work with ambiguity, and attention to detail. This position will have you collaborating with other members of Supply Chain, Quality Assurance, Regulatory Affairs, and Finance to execute and deliver endorsed global supply plans for both clinical and commercial supply. You will report to the Director, External Supply Operations.

Responsibilities

• Build and maintain productive relationships with external contract manufacturers (CMO’s), and internal global colleagues
• Ensure timely and effective execution of all manufacturing and supply plans at assigned CMO’s
• Develop and manage production processes to support operational execution, including BOM’s, specifications, CAPA’s, change controls, master data, and artwork. Familiarity with ERP/MRP systems
• Support logistics, transportation and import/export activities
• Act as the manufacturing and supply chain representative for review and approval of documentation including but not limited to batch records, BOM’s, specifications, artwork, and change control
• Support product qualification activities including but not limited to reviewing/approving IQ/OQ/PQs, stability, and validation protocols; review and approve change controls
• Play a key role in supporting selection and onboarding of new CMOs, technical transfers, operationalizing product supply and site establishment
• Manage and track inventory, perform inventory reconciliations, and support month end close process.
• Issue purchase orders, and track invoices and budgets
• Maintain production schedules and track batch record execution in coordination with Quality
• Oversee, review, and approve as necessary revisions to manufacturing cGMP and non GMP documentation
• Proven risk management acumen with a continuous improvement mindset
• Where necessary, provide input to the manufacturer and QA for evaluation of process deviations and assist in the investigation of product complaints
• Build and maintain strong partnerships and provide effective communication with all internal and external stakeholders and lead discussion, problem solving efforts and process improvements to ensure that performance targets are met or exceeded
• Responsible for scheduling and maintaining routine business operations meetings with CMO’s
• Support Regulatory submissions and CMC as required

Qualifications

Education & Core Experience

• BS/BA Degree in Life Science, Biology, or Engineering discipline from an accredited college or university, or equivalent desired
• 10+ years’ combined experience in manufacturing, outsourced operations, technical operations and/or supply chain in regulated healthcare industry, preferably within biotech/pharmaceutical industry
• cGMP career experience embedded in a pharmaceutical manufacturing plant is essential – with first-hand knowledge of plant operations, with the insight to assess performance, and diagnose issues directly at the source
• Technical background with knowledge of engineering and pharmaceutical manufacturing processes in small molecules is required, and experience in DS/API production is desirable
• Excellent problem-solving skills, with the ability to address complex challenges under time pressure
• Demonstrated expertise in risk management, with a history of successfully implementing risk mitigation strategies
• Hands-on investigations/RCA (OOS/OOT/deviations) and continuous improvement at external sites
• The ability to function in a fast-paced, high-growth, entrepreneurial environment
• Ability to travel domestically and internationally ~25%
• Position requires a strong working knowledge and understanding of both regional and international regulations by government agencies affecting the pharmaceutical industry (CFR's, EU GMP, ICH)
• Timely and effective communication across multiple audiences, both verbally and in writing
  
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Job purpose

As a Manager, External Manufacturing and Supply Operations, you are responsible for the end-to-end technical and operational oversight of external manufacturing and supply activities across a network of Contract Manufacturing Organizations (CMOs). This role sits at the core of Manufacturing and External Supply Operations and requires a strong technical foundation, the ability to manage multiple concurrent priorities, and to operate effectively in a fast-paced, ambiguous environment.

This position places particular emphasis on batch record review and approval, process oversight, and technical decision-making, ensuring that manufacturing activities are executed in full compliance with cGMP standards and aligned with global supply requirements.

You will collaborate cross-functionally with Quality Assurance, Technical Operations, Regulatory Affairs, and Supply Chain to ensure robust, compliant, and reliable supply for both clinical and commercial products. You will report to the Director, External Supply Operations.

Responsibilities

• Build and maintain strong, technically credible relationships with external CMOs and internal cross-functional stakeholders
• Provide hands-on technical oversight of manufacturing operations at CMOs, ensuring adherence to validated processes, regulatory expectations, and internal standards
• Own and lead the review and approval of batch records, ensuring accuracy, completeness, and compliance with cGMP and product specifications
• Act as the technical authority for batch disposition readiness and support, identifying and resolving issues that may impact product quality or release timelines
• Ensure prompt execution of manufacturing and supply plans, proactively identifying risks and implementing mitigation strategies
• Drive investigation and resolution of deviations, OOS/OOT events, and product complaints, including leading or supporting root cause analysis (RCA) and CAPA development
• Provide technical input and oversight for change controls, ensuring appropriate impact assessments and alignment with regulatory filings and process validation state
• Develop and support deep understanding of manufacturing processes (API, Drug Product, and Packaging) to enable effective troubleshooting and continuous improvement
• Review and approve technical documentation, including but not limited to:
  
  
  • Batch manufacturing and packaging records
  • Specifications and master data
  • Validation protocols and reports (IQ/OQ/PQ)
  • Stability protocols and reports
  • Change controls and deviations
    
    
• Support process validation and ongoing process verification, ensuring continued state of control at CMOs
• Play a key role in technology transfers, process scale-up, and site onboarding, ensuring technical robustness and successful execution
• Partner with Quality and CMO teams to monitor batch execution in real time, ensuring proactive issue identification and resolution
• Ensure effective management of BOMs, master data, and ERP/MRP systems to support accurate production planning and execution
• Lead or participate in routine governance and operational meetings with CMOs, driving accountability and performance improvements
• Support regulatory submissions and CMC activities, ensuring technical accuracy and consistency with manufacturing processes
• Maintain oversight of inventory, production schedules, and supply continuity, ensuring alignment with demand and minimizing supply risk
• Drive a continuous improvement culture, identifying opportunities to enhance process robustness, reduce deviations, and improve right-first-time performance

Qualifications

Education & Core Experience

• BS/BA Degree in Life Sciences, Engineering, or related discipline desirable
• 10+ years’ experience across pharmaceutical manufacturing, technical operations, or external supply in a regulated environment
• Strong cGMP manufacturing experience within a pharmaceutical plant environment, with direct exposure to shop-floor operations and batch execution
• Demonstrated expertise in batch record review and approval, with a deep understanding of critical process parameters, in-process controls, and data integrity
• Proven experience working with external CMOs, providing technical oversight and driving performance in outsourced manufacturing environments
• Strong technical knowledge across Drug Product, API, and Packaging operations, with the ability to troubleshoot complex manufacturing issues
• Hands-on experience in deviation management, investigations (OOS/OOT), and CAPA implementation
• Solid understanding of process validation, lifecycle management, and continued process verification
• Experience supporting or leading technology transfers and process scale-up activities
• Strong working knowledge of global regulatory requirements (FDA, EMA, ICH, EU GMP)
• Experience with ERP/MRP systems and manufacturing data structures (BOMs, master data)
• Proven ability to apply risk management principles and make sound technical decisions under pressure
• Excellent communication skills, with the ability to clearly articulate complex technical issues to diverse stakeholders
• Ability to operate effectively in a fast-paced, high-growth environment, managing multiple priorities simultaneously
• Willingness to travel (~25%) to support CMO oversight and on-site technical activities
  
  #LI-HYBRID