GeneDx (Nasdaq: WGS) delivers personalized and actionable health insights to inform diagnosis, direct treatment, and improve drug discovery. The company is uniquely positioned to accelerate the use of genomic and large-scale clinical information to enable precision medicine as the standard of care. GeneDx is at the forefront of transforming healthcare through its industry-leading exome and genome testing and interpretation services, fueled by the world’s largest, rare disease data sets. For more information, please visit www.genedx.com.

Summary

The Manager of Internal Audit will play a pivotal role in building, executing and enhancing the company’s newly revamped internal audit function, with a strong emphasis on Sarbanes-Oxley (SOX) compliance and operational audits. This individual will contribute to building a scalable and effective audit program, supporting risk management, control evaluation, and governance processes. The role requires someone who can manage co-sourced resources, collaborate across departments, and deliver value-added insights to improve business processes and controls. Reporting to the Head of Internal Audit, this role will work closely with finance, operational, and other members of management to maintain transparency, integrity, and accountability within the organization. 

This position will be hybrid in office two days per week in Stamford, CT and may require occasion travel (~20%). 

Job Responsibilities

• Lead and manage assigned areas of the SOX program, including risk assessment, scoping, testing, and reporting. 
• Perform walkthroughs and document business processes, risks, control activities, and supporting technologies. 
• Review workpapers and assess the design and operating effectiveness of internal controls. 
• Draft and deliver audit results, ensuring timely and actionable feedback to stakeholders. 
• Serve as a subject matter expert on SOX, risk, and control, advising business and risk partners. 
• Ability to formulate opinions and communicate perspectives to stakeholders in a timely manner. 
• Conduct audits and ad-hoc internal audit projects aligned with the annual audit plan. 
• Manage multiple workstreams at the same time and prioritize tasks for team members. 
• Provide training and guidance to internal audit staff and control owners on SOX requirements and best practices. 
• Identify opportunities for process improvement and control enhancement. 
• Collaborate with external auditors, co-sourced partners, and internal stakeholders. 
• Support the growth of the internal audit function, including recruiting and onboarding efforts. 
• Contribute to the evolution of audit practices by incorporating emerging technologies and process refinements. 
• Participate in company-wide risk assessments and integrate findings into audit planning. 
• Maintain awareness of regulatory changes and industry best practices.
  
  

Education, Experience, and Skills

• Bachelor’s degree in Accounting, Finance, Economics, IT or other related field; advanced degree a plus. 
• Certified Internal Auditor (CIA) or Certified Public Accountant (CPA) required. 
• 7+ years of experience in auditing and/or compliance, including SOX program management. 
• Experience managing co-sourced resources and leading audit teams. 
• Strong understanding of internal control frameworks, financial reporting, enterprise risk frameworks. 
• Familiarity with enterprise resource planning (ERP) systems, GRC platforms, and audit management software. Experience with NetSuite or Audit Board a plus. 
• Experience within the Healthcare industry. 
• Excellent project management, analytical, and communication skills. 
• Ability to build relationships across all levels of the organization. 
• High attention to detail and commitment to accuracy and transparency. 
• Ability to work in a fast paced, action-oriented environment. 
  
  

Work Environment 

This is a hybrid position requiring both in-office and remote work. The employee will work from our office location in Stamford, CT and remotely from a home office or other suitable location with reliable high-speed internet access. In-office work is performed in a professional office setting with standard lighting, temperature control, and low to moderate noise levels. Remote work is performed in a climate-controlled environment. Standard office equipment including computer, phone, and video conferencing tools are used in both settings. Your standard work schedule and hours will be established in collaboration with your leader and may be adjusted to align with evolving business needs. 

Physical Demands 

 This is a sedentary role with physical demands including: 

• Sitting for extended periods (up to 8 hours per day).
• Repetitive use of hands and fingers for typing and mouse operation.
• Visual acuity for reading computer screens and documents.
• Ability to communicate effectively in person, by phone, and via video.
• Occasional standing, walking, and reaching for files or supplies.
• Occasional lifting of up to 15 pounds (files, office supplies, equipment).
• Ability to commute to office location as required. 

Reasonable accommodations may be made to enable individuals with disabilities to perform the essential functions of this position.