The Data Platforms Health team builds native platform solutions that enable healthcare-specific platform capabilities. This development role in the Database Platforms department will contribute to AI-based features and workflows within the InterSystems Health Connect Cloud, InterSystems FHIR Server, InterSystems IRIS for Health and InterSystems Health Connect products.

The team needs a developer who can drive AI model and AI architecture design and development for intelligent tooling features for healthcare builders and administrators. The team also needs thought leadership to adopt evolving AI technologies so that InterSystems can be a leader in AI-driven features and workflows.

You are encouraged to apply if this role sounds interesting to you, even if you have doubts about being a competitive candidate. InterSystems prides itself on investing in its team members.

This position is in the InterSystems headquarters in Boston, MA.

Responsibilities

You will design, build, train, and deploy machine learning and agentic AI models, and consume LLMs and custom models using REST APIs. Working with product management and support specialists, you will design and implement data cleansing and feature extraction tools to improve the accuracy of predictions and data generation for a healthcare setting. Your responsibilities will include integrating the models into existing products and refining the models to meet evolving product needs.

All work must follow the team’s development workflow including use of source control, design and code reviews, and clear documentation. You are responsible for the quality of your code and must design automated tests to verify the effectiveness of the models and features.

This role will require you to respond to technical questions about expected product behavior and recommended best practices from support specialists and sales engineers. You will also collaborate with the release engineering team to ensure that your model and tools are appropriately deployed in cloud and on-prem environments.

The technology stack includes Python, AWS Bedrock, ObjectScript, and InterSystems IRIS.

As a leader, you are expected to create project plans with estimates, track execution against the plan, and proactively communicate anticipated delays in the project. With support from your manager, you will coordinate with other teams and overcome blockers and inter-team misalignments to deliver your projects. You will also provide thought leadership in the areas of Gen AI, agentic AI, and other evolving technologies, and encourage other team members to adopt these technologies for the platform.

Qualifications Required

• Bachelor’s degree in Computer Science, Engineering, or a related technical discipline.
• 8+ years of hands-on professional experience as a software developer or similar. Open to considering less experience in combination with a Graduate degree.
• Experience with data analysis, data cleansing, feature extraction, and model training.
• Experience with Python and common libraries like Pandas, NumPy, and Scikit-learn.
• Experience with model training and evaluation.
• Experience with Agent orchestration and runtime, MCP, tool registration, and multi-model routing.
• Experience with design or consumption of REST APIs.
• Strong verbal and written communication skills.

Preferred Qualifications

• Self-starter with curiosity to experiment and learn, and confidence to challenge the status quo.
• Professional experience with machine learning algorithms like neural networks and LLMs.
• Professional experience with programmatic access of LLMs and/or open-source models.
• Experience with observability of model performance and runtime costs.
• Experience with model governance and design of guardrails for model security.
• Professional experience with deep learning libraries like TensorFlow, PyTorch, or Keras.
• Professional experience with health messaging standards, especially FHIR.
• 3+ years of experience with other programming languages like Java, C#, C++, or ObjectScript.

We are an equal-opportunity employer and do not discriminate because of race, color, religion, sex, national origin, ancestry, marital status, veteran status, age, disability, sexual orientation or gender identity or expression or any other legally protected category. InterSystems is an E-Verify Employer in the United States.

We are looking for a Manager, Customer Success Engineering (AI & Cloud Support) who is passionate about delivering exceptional support experiences and building high-performing teams.

As a Manager, CSE (AI & Cloud Support) at DigitalOcean, you will operate as a Support Manager leading a team of Customer Success Engineers (CSEs) supporting strategic customers across cloud infrastructure and emerging AI/ML workloads. Reporting to the Senior Manager of Customer Success Engineering, you will own day-to-day support operations, team performance, and customer experience outcomes.

This role is focused on driving operational excellence while building strong technical depth within the team across AI, GPUs, Kubernetes, Databases and core cloud offerings. You will play a key role in ensuring consistent support coverage, developing SMEs, and partnering cross-functionally with Product and Engineering to improve both customer experience and product quality.

The ideal candidate brings a deep understanding of cloud and AI/ML ecosystems, including machine learning operations (MLOps), and enterprise support, combined with a passion for innovation and automation, and a proven ability to lead teams in delivering “white-glove” experiences for strategic customers.

What You’ll Do:

Team Leadership & Development

• Lead, hire, train, mentor and develop a high-performing team of Customer Success Engineers (CSEs), driving accountability, performance, and career growth
• Establish performance metrics (KPIs/SLAs) and conduct regular 1:1s, performance reviews, and career development planning.
• Own end-to-end support operations, including queue management, escalations, and shift planning to ensure consistent 24x7 coverage.
• Drive improvements in key support metrics such as CSAT, response times, resolution times, and overall support quality.
• Build and strengthen technical expertise within the team across core areas such as Kubernetes (DOKS), Databases, Compute, and AI/ML workloads.
  
  

Strategic Customer Support

• Act as the ultimate point of technical escalation for our largest, most strategic enterprise customers across Cloud and AI/ML workloads, stepping in to manage critical incidents and high-severity (Sev1/Sev2) issues.
• Design and implement customized support plans, SLAs, and escalation pathways tailored to the needs of strategic accounts.
• Partner closely with Technical Account Managers (TAMs), Growth Account Managers (GAM) to conduct Executive Business Reviews (EBRs) and ensure customers are maximizing the value of our Cloud and AI/ML products.
• Proactively identify risks and opportunities within strategic accounts to improve customer experience, adoption, and retention.

Technical & Cross-Functional Operations

• Serve as the Voice of the Customer (VoC) to Product and Engineering teams, synthesizing support data to advocate for bug fixes, feature requests, and UX improvements.
• Own and continuously improve escalation protocols between AI/ML Support and CloudOps, Infrastructure Engineering, and Product — including Jira escalation routing, Sev1 bridge management, and post-incident documentation.
•  Own the development and maintenance of SOPs, escalation runbooks, HVC support playbooks, and knowledge base content — treating documentation infrastructure as a core operational lever for team scalability.
• Contribute to the vision for AI and automation within support—building intelligent tooling and driving the team toward an automation-first model to improve efficiency, scalability, and customer experience.
• Foster a culture of continuous learning, ensuring the team stays ahead of evolving cloud technologies, AI/ML frameworks, and industry trends.

Key Metrics:

• Customer Satisfaction (CSAT) for strategic accounts
• Time to Response and Resolution (TTR) for strategic customers
• Tier 1 resolution rate vs. escalation rate
• Time-to-escalation and engineering handoff SLA adherence
• SLA adherence and escalation response times
• Support productivity and quality (QA scores)
• Post-incident documentation completion rate

What You’ll Add to DigitalOcean:

• Experience: 5+ years of experience in Technical Support, Customer Success, or Technical Account Management within B2B SaaS, Cloud, or AI/ML environments ideally including experience supporting AI-native, high-growth companies with 24x7 production dependencies on GPU infrastructure.
• Leadership: 2+ years of people management experience leading technical, customer-facing teams, preferably in a high-growth, post-acquisition, or rapidly scaling environment.
• Technical Domain Expertise: Solid understanding of AI/ML concepts, including Generative AI, Large Language Models (LLMs), natural language processing (NLP), and MLOps. Deep familiarity with GPU infrastructure (NVIDIA H100/H200, bare metal GPU provisioning) and AI inference workloads is strongly preferred.
• Coding/Integration: Proficiency in reading and debugging code (Python preferred) and troubleshooting RESTful APIs and cloud architecture.
• Communication: Excellent verbal and written communication skills, with the ability to translate complex technical or AI concepts for diverse audiences OR to both highly technical engineers and non-technical business executives.
• Problem-Solving: Proven ability to remain calm under pressure and de-escalate high-stakes situations with enterprise clients.

Preferred Qualifications:

• Hands-on experience with ML frameworks (e.g., TensorFlow, PyTorch, Scikit-learn) and AI toolchains (e.g., LangChain, Hugging Face).
• Experience with major cloud platforms (AWS, Google Cloud, Azure) and their native AI/ML services.
• Bachelor’s or Master’s degree in Computer Science, Data Science, Engineering, or a related technical field.
• ITIL or equivalent service management certification

Compensation Range: 

• $125,000 - $153,000

*This is a remote role

JR: 2026-7692

#LI-Remote

Position

Manifold's AI team is actively training protein foundation models on our proprietary experimental datasets. Our generative antibody design model, mBER, has already demonstrated controllable de novo binder design across multiple million-scale screening campaigns, and the team is now scaling foundation model capabilities to push well beyond current performance. We are looking for an AI/ML Scientist to join this effort. You will work alongside our existing model training team to accelerate the development of foundation models fine-tuned on Manifold's data, bringing additional depth in pre-training methodology, architecture development, and large-scale training. Your work will directly improve mBER's design capabilities and unlock new modeling paradigms for the broader team. You'll own foundation model projects end-to-end, from architecture selection and training infrastructure to evaluation against real experimental outcomes, while contributing to the team's shared research agenda.

This is an on-site role and can be based in either Boston, Massachusetts or San Francisco, California. Please only apply if you reside in these cities or are open to relocate. 

Responsibilities

• Advance the team's ongoing foundation model training efforts—pretraining, fine-tuning, and evaluating folding, docking, language, and generative design models on Manifold's proprietary experimental data
• Bring depth in training methodology, architecture selection, and optimization to complement the existing team's expertise
• Develop and scale training pipelines for distributed, multi-GPU and multi-node training runs
• Integrate foundation model outputs into mBER to improve binder design success rates and enable new design capabilities
• Design and execute ML experiments with clear hypotheses, rigorous evaluation frameworks, and systematic analysis
• Establish best practices for mixed-precision training, gradient checkpointing, and computational efficiency at scale
• Produce clear documentation and analysis supporting architecture and training decisions

Required Qualifications

• Demonstrated experience pretraining and/or fine-tuning protein foundation models (folding, docking, language models, or generative design) with published or otherwise demonstrable results
• Strong familiarity with AlphaFold architecture and training methodology
• 2+ years of hands-on experience with PyTorch and/or JAX for deep learning
• Experience with large-scale model training: distributed training, multi-GPU/multi-node setups, mixed precision, gradient checkpointing
• Solid understanding of deep learning architectures (transformers, attention mechanisms, diffusion/flow matching) and optimization techniques
• Experience working with protein structure data (PDB, mmCIF) and/or protein sequence datasets
• Strong statistical analysis and experimental design skills
• Proficiency in Python scientific computing stack (NumPy, Pandas, scikit-learn)
• Self-directed researcher who can balance guidance with independence
• Excellent written and verbal communication skills for cross-functional collaboration

Preferred Qualifications

• Experience with protein generative design methods (e.g., RFdiffusion, ProteinMPNN, flow matching approaches)
• Experience with protein language models (e.g., ESM family)
• Published research in computational biology, protein design, or structural biology
• Experience training on proprietary or domain-specific biological datasets
• Familiarity with Ray for distributed computing
• Experience with Kubernetes (EKS) and cloud computing platforms (AWS)
• Knowledge of protein engineering, directed evolution, or structural biology wet lab techniques
• Experience working with agentic AI coding tools for fast, parallelized execution of modeling experiments
• Previous biotech/pharma industry experience

This Role Might Be Perfect For You If:

• You have deep experience training protein foundation models and want to apply that expertise to some of the richest proprietary experimental datasets in the field
• You're excited about pushing beyond public model performance by leveraging unique, large-scale in vivo screening data
• You thrive in high-ownership roles where you can drive research direction while collaborating with a tight-knit, world-class team
• You want your models to directly impact real drug discovery programs

If you're excited to train the next generation of protein foundation models on uniquely powerful experimental data, please reach out to careers@manifold.bio.

Base Salary Range: $140,000-225,000

This reflects the typical offer range for this role, based on experience, role scope, and internal equity. Final compensation decisions are made using a consistent leveling framework and consider the candidate’s experience, interview performance, and expected impact.

This role is eligible for:

• Annual performance-based target bonus
• Stock options
• Comprehensive medical, dental, and vision coverage
• 401(k) plan
• Flexible paid time off and holidays
• Perks including on-site gym, onsite lunch, and commuter support

Our compensation ranges are reviewed annually to ensure alignment with market trends and internal equity.

Position Summary

We are seeking a skilled Machine Learning Engineer with approximately three years of hands-on experience designing, deploying, and maintaining production-grade machine learning systems. In this role, you will collaborate closely with data scientists, software engineers, and product teams to translate research models into reliable, scalable, and high-impact applications. You will be deeply involved in the end-to-end ML lifecycle—from data ingestion and feature engineering to deployment, monitoring, and continuous improvement—playing a critical part in shaping our machine learning platform and capabilities.

Primary Responsibilities

• Develop, deploy, and optimize machine learning models for real-world business use cases and client-facing applications.
• Partner with data scientists to operationalize predictive models and ensure scalable, maintainable, and performant production deployments.
• Design and implement data pipelines and workflows that support training, inference, and model lifecycle management.
• Work with large, complex datasets to ensure data quality, reproducibility, and reliable version control across ML workflows.
• Implement model monitoring, logging, and alerting strategies to track performance, detect drift, and support retraining cycles.
• Leverage cloud platforms (AWS, Azure, GCP) to build scalable ML solutions using managed services and infrastructure-as-code practices.
• Write clean, modular, and well-documented code aligned with MLOps and software engineering best practices.
• Stay current on emerging ML tooling, frameworks, and industry best practices to continuously enhance our platform and capabilities.

Qualifications

• Master’s degree in Computer Science, Data Science, Engineering, or a related technical field.
• 6+ years of experience in machine learning engineering, applied ML, or related software engineering roles.
• Strong proficiency in Python and experience with modern ML frameworks such as TensorFlow, PyTorch, or scikit-learn.
• Experience with distributed data processing and compute frameworks (e.g., Pandas, Spark, Dask).
• Hands-on experience with containerization and orchestration technologies such as Docker and Kubernetes.
• Familiarity with CI/CD pipelines, testing automation, and version control using Git.
• Experience working with cloud-based ML platforms or services (e.g., SageMaker, Vertex AI, Databricks, or Snowflake ML) is preferred.
• Strong understanding of model evaluation, feature engineering, and performance optimization in production contexts.
• Excellent analytical, communication, and collaboration skills, with the ability to work effectively in cross-functional teams.

This is an exempt position. The annualized base pay range for this role is expected to be between $140,000-$180,000.  Actual base pay could vary based on factors including but not limited to experience, subject matter expertise, geographic location where work will be performed, and the applicant's skill set.  The base pay is just one component of the total compensation package for employees.  Other rewards may include an annual cash bonus and a comprehensive benefits package, including but not limited to medical, dental, vision, life and 401(k). Please note that the job title is subject to change based on the selected candidate’s experience and education.

Position

Manifold Bio is seeking a talented Machine Learning Research Engineer to join our growing AI team. You will work closely with our research scientists to implement, scale, and optimize machine learning systems that power our de novo antibody design platform and advance our protein design capabilities. Your efforts will contribute to building production-ready ML infrastructure that enables breakthrough discoveries in protein therapeutics. You will be expected to take ownership of engineering challenges in our ML pipeline, from data processing and model training to deployment and monitoring, while collaborating closely with our research team to translate cutting-edge ideas into robust, scalable systems.

This is an on-site role and can be based in either Boston, Massachusetts or San Francisco, California. Please only apply if you reside in these cities or are open to relocate. 

Responsibilities

• Implement and optimize machine learning models for protein design
• Build and maintain scalable data processing pipelines for large-scale protein and molecular datasets
• Develop and deploy ML infrastructure for distributed training and inference across GPU clusters
• Collaborate with research scientists to translate experimental ML approaches into production-ready code
• Design and execute ML experiments with clear hypotheses and rigorous analysis
• Optimize model performance and computational efficiency for large-scale protein design tasks
• Build tools and utilities to support rapid prototyping and experimentation by the research team

Required Qualifications

• Bachelor's or Master's degree in Computer Science, Machine Learning, Computational Biology, or related field
• 2+ years of hands-on experience with PyTorch and/or JAX for deep learning applications
• Strong proficiency in Python scientific computing stack (NumPy, Pandas, scikit-learn)
• Experience with distributed computing and GPU optimization techniques
• Familiarity with protein structure analysis, computational biology, or analogous problems in natural sciences
• Understanding of modern deep learning architectures and optimization techniques
• Experience implementing research papers or translating ML approaches to production systems
• Proficiency with version control (Git), testing frameworks, and software engineering best practices
• Strong problem-solving skills and ability to work independently on technical challenges
• Excellent written and verbal communication skills for cross-functional collaboration

Preferred Qualifications

• Experience training LLMs or diffusion generative models
• Knowledge of cloud computing platforms (AWS, GCP) and containerization (Docker, Kubernetes)
• Background in computational biology, bioinformatics, or structural biology
• Experience with large-scale data engineering and ETL pipelines
• Familiarity with MLOps practices and model deployment frameworks

This Role Might Be Perfect For You If

You are passionate about leveraging state of the art machine learning approaches to solve challenging disease areas

• You enjoy translating research ideas into high impact, productionized, scalable code
• You have rich AI/ML experience and are looking to pivot into biotech

If you're excited to build scalable ML systems that revolutionize protein therapeutic discovery, please reach out to careers@manifold.bio.

Base Salary Range: $140,000-225,000

This reflects the typical offer range for this role, based on experience, role scope, and internal equity. Final compensation decisions are made using a consistent leveling framework and consider the candidate’s experience, interview performance, and expected impact.

This role is eligible for:

• Annual performance-based target bonus
• Stock options
• Comprehensive medical, dental, and vision coverage
• 401(k) plan
• Flexible paid time off and holidays
• Perks including on-site gym, onsite lunch, and commuter support

Our compensation ranges are reviewed annually to ensure alignment with market trends and internal equity.

Who We Are

PathAI's mission is to improve patient outcomes with AI-powered pathology. Our platform promises substantial improvements to the accuracy of diagnosis and the efficacy of treatment of diseases like cancer, leveraging modern approaches in machine learning and artificial intelligence. We have a track record of success in deploying AI algorithms for histopathology in translational research, pathology labs and clinical trials.  Rigorous science and careful analysis is critical to the success of everything we do. Our team, composed of diverse employees with a wide range of backgrounds and experiences, is passionate about solving challenging problems and making a huge impact on patient outcomes.

Where You Fit 

As the Associate Director, MLOps Lead, you will lead the team responsible for the backbone of our AI/ML Stack: the infrastructure that bridges ML research and massive-scale production. Your primary directive is to evolve our stack to meet the next scale of needs in large scale ML training & inference workloads.  

You’re someone who enjoys designing and building for reliability, relishes collaboration and technical challenges, and takes pride in making things better – without taking yourself too seriously. Our technical space is broad: high-scale AI training & inference workloads, cloud infrastructure, Kubernetes, observability, distributed systems, and a bit of everything in between.

What You’ll Do

This role is critical for driving the scalability and efficiency of our Machine Learning Operations platform with high-impact & high growth strategic initiatives. 

• Vision and Roadmap: Develop and execute the long term vision & roadmap for MLOPs team to support ML development and deployment needs across the business units. Successfully manage the tension between short-term tactical deliveries and long-term architectural transformation for future growth. 
• Team Management: Lead and mentor a team of 6-7+ high-performing engineers. Strategically allocate resources to manage support for existing services while executing key strategic initiatives.
• Cross-Functional Collaboration: Partner with leaders across machine learning, data science, product engineering, and infrastructure to proactively identify pain points, address bottlenecks, and facilitate the deployment of new solutions.
• Foundation Model Readiness: Architect the compute and storage pipelines required for ML Engineers to manage millions of slides and complex derived artifacts without data fragmentation or synchronization latency.
• Inference Modernization: Modernize the AI Product inference stack to support 5-10x growth of AI runs across global deployments.
• System Observability: Collaborate with Site Reliability Engineering (SRE) to establish comprehensive metrics covering compute under-utilization, network bottlenecks, and granular cost and turn-around-time attribution.
• Technology Refresh: Conduct "Build vs. Buy" assessments, leading "Stack Refresh" audits to benchmark our proprietary tools against best-in-class commercial and open-source alternatives to meet our future needs.

What You Bring

To be successful in this role with us, you'll at least need:

• Bachelor’s or Master’s degree in Computer Science, Engineering, or a related field (or equivalent experience).
• 2-3+ years of experience managing engineering team(s), with a focus on building production-grade frameworks for MLOps or ML Infrastructure.
• Deep technical expertise with ML workloads on kubernetes, cloud computing platforms (AWS/GCP/Azure), workflow orchestration (Airflow, Kubeflow, or proprietary equivalents) and DevOps principles and infrastructure-as-code (Helm, Terraform).
• Proven experience managing petabyte-scale datasets and high-throughput production inference pipelines.
• Strong software engineering skills in complex, multi-language systems and experience with scalable service architecture.
• Use of AI assistants (e.g. CoPilot, Cursor, Claude) across platform development lifecycle.

It Would Be Great If You Also Have

• Exposure to ML frameworks like PyTorch or Scikit-learn.
• Experience with large-scale data processing frameworks (e.g. Spark, Hive, Databricks, Amazon EMR)
• Expertise in MLOps principles, including model lifecycle management, feature stores, model monitoring, and CI/CD for ML.
• Familiarity with security and compliance best practices in ML systems.

We Want To Hear From You

At PathAI, we are looking for individuals who are team players, are willing to do the work no matter how big or small it may be, and who are passionate about everything they do. If this sounds like you, even if you may not match the job description to a tee, we encourage you to apply. You could be exactly what we're looking for. 

PathAI is an equal opportunity employer, dedicated to creating a workplace that is free of harassment and discrimination. We base our employment decisions on business needs, job requirements, and qualifications — that's all. We do not discriminate based on race, gender, religion, health, personal beliefs, age, family or parental status, or any other status. We don't tolerate any kind of discrimination or bias, and we are looking for teammates who feel the same way.

The cash compensation outlined below includes base salary or hourly wage and on-target commission for employees in eligible roles. The summary below indicates if an employee in this position is eligible for annual bonus, overtime pay and equity awards. Individual compensation packages are tailored based on skills, experience, qualifications, and other job-related factors. 

Annual Pay Range:
AD, MLOps: $181,500 - $278,300

Not Overtime Eligible

Eligible for Equity

Toast creates technology to help restaurants and local businesses succeed in a digital world, helping business owners operate, increase sales, engage customers, and keep employees happy.

The Customer Success Data and Analytics (CSDA) team supports Care Operations, Customer Success, Education, and Voice of the Customer. We are building a new generation of data products that extract structured, actionable insight from unstructured customer interactions using NLP, ML, and LLM-based approaches.

As the Principal Data Product Manager, Applied AI, you will own the agenda for how AI-enriched data improves our understanding of the customer experience. You will prototype, validate, and scale a portfolio of AI-powered data products that give our CS organization insight it has never had before. You will also serve as a resource and thought partner for teammates and other teams across Toast who are working with CS data in an AI context, helping make that work faster, more consistent, and more reliable.

This is a hands-on, high-ownership role. You will spend time in Snowflake and Hex building things, and you will spend time with CS leaders explaining what those things mean and why they matter. The right person for this role is equally comfortable doing both.

A Day in the Life (Responsibilities)

Enablement and Shared Practice

• Technical Resource: Serve as the go-to resource on applied AI and NLP with CS data for your CSDA teammates and other teams across Toast.
• Best Practices: Build and maintain a practical library of guidance regarding successful prompts, pitfalls to watch for, and how to structure CS data for AI use cases.
• Market Intelligence: Stay current on how CS data is being used with AI tools across the organization to keep CSDA ahead of the curve.
• Facilitation: Act as a facilitator for AI prototyping work, helping analysts and stakeholders structure experiments so outputs are reliable and usable.

Applied AI and ML Product Development

• Portfolio Ownership: Drive an active portfolio of prototyping work focused on enriching the CSDA data model with insight extracted from unstructured contact data.
• Strategic Focus: Focus on contact classification, intelligent summarization, sentiment analysis, churn signal detection, and product mention extraction.
• End-to-End Design: Manage the pipeline from problem framing and prompt design to embedding generation, classifier training, and final production.
• Stakeholder Validation: Run structured validation processes, including codebook reviews and labeling sessions, to earn trust before products scale.

Scaling and Productionalization

• Readiness Framework: Maintain a clear framework for deciding what is ready to scale based on business value, quality, and maintenance requirements.
• Engineering Partnership: Partner closely with the CSDA data engineering team to scope and hand off production-grade implementations.
• Quality Governance: Own the quality review process for AI products in production, including monitoring for output drift and driving recalibration.
• Product Advocacy: Serve as the face of these products with stakeholders, explaining how they work and being honest about their limitations.

What You’ll Need to Thrive (Requirements)

• Relevant Experience: 6+ years of experience in analytics, data science, ML, or NLP in a data-intensive environment.
• AI Fluency: Practical fluency with LLMs, including prompt engineering, structured output extraction, and model evaluation.
• Product Instincts: You think about what you are building in terms of who uses it and how you will know if it is working.
• Project Leadership: Strong program and stakeholder management skills with the ability to move things forward without formal authority.
• Technical Expertise: Applied experience with text data and NLP/ML techniques such as LLMs, classifiers, or embeddings.
• Core Skills: Expert-level SQL and solid Python proficiency with the ability to build and iterate on ML pipelines independently.
• Communication Mastery: Ability to explain complex classification pipelines to non-technical leaders and push back on requirements when necessary.

What Will Help You Stand Out (Nice to Haves)

• Specific Tooling: Experience with Snowflake Cortex, including COMPLETE and EMBED_TEXT functions.
• Library Familiarity: Familiarity with scikit-learn, spaCy, Hugging Face, or sentence-transformers.
• Domain Expertise: Prior work in a Customer Success, Care, or CX analytics context.
• Workflow Design: Experience building human-in-the-loop validation workflows or labeling interfaces.
• Proven Impact: A track record of prototyping things that made it into production and were successfully used.

AI at Toast

At Toast, one of our company values is that we're hungry to build and learn. We believe learning new AI tools empowers us to build for our customers faster, more independently, and with higher quality. We provide these tools across all disciplines, from Engineering and Product to Sales and Support, and are inspired by how our Toasters are already driving real value with them. The people who thrive here are those who embrace changes that let us build more for our customers; it’s a core part of our culture.

Our Total Rewards Philosophy 
We strive to provide competitive compensation and benefits programs that help to attract, retain, and motivate the best and brightest people in our industry. Our total rewards package goes beyond great earnings potential and provides the means to a healthy lifestyle with the flexibility to meet Toasters’ changing needs. Learn more about our benefits at https://careers.toasttab.com/toast-benefits.

Role overview

The Manager, Data Science will lead an Inventory & Dealer Data Science team focused on developing, deploying, and optimizing machine learning models that power CarGurus’ products and business insights. Sitting within the broader Data Science organization, this team is responsible for modeling automotive marketplace dynamics and dealer behavior. The team owns Machine Learning solutions end-to-end across the ML lifecycle, from R&D to production. This leader is accountable for the team’s strategic direction and impactful delivery, while building a culture of innovation, technical excellence, and collaboration. The Manager partners with Product, Engineering, Analytics, and cross-functional stakeholders to ensure team efforts advance CarGurus’ goals in intelligence-powered products.

What you'll do

• Oversee the development, training, and evaluation of machine learning models covering Inventory and Dealer intelligence. Leverage modeling techniques including recommendations, demand forecasting, churn risk prediction, and valuation algorithms.
• Facilitate experimentation, A/B testing, and measurement of production models, ensuring robust evaluation of business impact
• Build and develop a high-performing team - providing regular coaching, feedback, and performance assessments; ensure equitable access to growth opportunities.
• Drive innovation, continuous improvement, and adoption of best-in-class ML and AI practices. Champion best practices across the organization.
• Participate in roadmap planning, aligning the team’s work with broader business priorities and long-term strategy. Flag resource constraints and escalate tradeoff decisions when needed.
• Act as a visible, accessible leader - communicating objectives, updates, risks, and wins to all stakeholders.
• Partner with peers in the Machine Learning Platform, Product and Data teams, and other stakeholders to facilitate effective cross-team working relationships and represent data science in cross-functional forums.

What you'll bring

• 5+ years of experience in a data science or machine learning engineering role
• 2+ years of people leadership experience
• Deep expertise in machine learning models and their application to classification, regression, ranking, and recommendation problems. Familiarity with standard evaluation metrics and statistical best practices.
• Experience deploying and owning models in production and a working understanding of MLOps practices.
• Strong working knowledge of Python development best practices and the Python ML ecosystem (e.g., scikit-learn, PyTorch, XGBoost, numpy, pandas).
• Experience with cloud platforms, particularly AWS, including deploying, monitoring, and troubleshooting ML models.
• Effective communication and facilitation abilities with both technical and non-technical stakeholders (including data scientists, product management, senior leadership, and engineers).
• Experience contributing to the technical direction for a team and a strategic mindset for prioritizing projects and aligning them with business goals.
• Knowledge of standard software development methodologies and a history of driving continuous improvement.
• Experience in a collaborative, cross-functional environment, with the ability to build effective working relationships and foster an inclusive team culture.

Summary

Klaviyo is looking for a Lead Data Science Analyst to join our GTM Strategic Analytics & Insights team. In this role, you will serve as a senior individual contributor at the intersection of advanced data science, AI/LLM-driven innovation, and Go-to-Market strategy. You will build and maintain sophisticated predictive and inferential models, conduct deep-dive statistical analyses, and develop AI-first solutions that unlock meaningful insights across the pre and post Sales Customer lifecycle.

The successful candidate will partner closely with GTM leadership to shape how Klaviyo understands, measures, and accelerates new business and customer outcomes; from pre-sales motion through onboarding, expansion and retention. You will operate with a strong bias toward AI-augmented workflows and bring a modern, LLM-aware approach to every analytical challenge.

The ideal candidate is intellectually curious, strategically minded, and energized by hard problems. They bring deep technical fluency across the full data science stack, a demonstrated ability to influence senior stakeholders through clear storytelling, and a genuine commitment to building AI-first solutions in a fast-moving SaaS environment.

How You Will Make a Difference

• Build and maintain advanced models: Build and maintain advanced predictive and time-series models: design, train, deploy, and monitor models across use cases such as demand forecasting, capacity planning, deal scoring, and customer propensity; incorporate seasonality, exogenous drivers, and backtesting frameworks to ensure accuracy and robustness
• Apply statistical rigor: lead deep-dive analyses leveraging regression, causal inference, hypothesis testing, correlation analysis, and other statistical methods to surface actionable signals from complex, large-scale datasets
• Develop AI/LLM-powered solutions: architect and implement AI-first analyses and tooling using large language models, prompt engineering, retrieval-augmented generation (RAG), and related techniques to automate insight generation, surface qualitative signals at scale, and augment team capabilities
• Own forecasting and decision systems: Own end-to-end forecasting and operational decision systems, including time-series demand forecasting, capacity planning models (e.g., Erlang-based staffing), and production pipelines that power GTM and Support planning workflows; ensure reliability, scalability, and business adoption of outputs
• Drive customer intelligence: develop and maintain prospect, deal health, archetype, and capacity models that inform GTM strategy, planning, and growth initiatives
• Define the measurement framework: identify, create, and steward benchmarks and metrics that meaningfully represent growth, engagement, and success outcomes
• Communicate with impact: distill complex analyses into clear, cohesive narratives with executive-ready materials that drive decisions at the senior leadership level
• Collaborate cross-functionally: partner with Systems & Engineering, GTM Operations, Rev Ops & Planning, Product, Business Intelligence, Data Science, and Finance to ensure analytical solutions are integrated, scalable, and trusted

Who You Are

• 6+ years of professional experience in an advanced analytics or data science role; SaaS experience strongly preferred
• Deep expertise in statistical inference and modeling, including supervised techniques (regression, classification, gradient boosting, decision trees) and unsupervised techniques (clustering, PCA, anomaly detection, topic modeling)
• Hands-on experience designing and deploying AI/LLM-based solutions, including prompt engineering, fine-tuning, RAG pipelines, or LLM-integrated analytics workflows; you approach new problems with an AI-first mindset
• Familiarity and experience with distributed coding projects, including using Git for code management.
• Advanced proficiency in Python (pandas, numpy, scikit-learn, xgboost, statsmodels, and LLM/AI libraries such as LangChain, OpenAI SDK, or HuggingFace) and SQL; working knowledge of DBT
• Own and scale end-to-end data pipelines, including orchestration with Airflow and transformation/modeling with dbt; design reliable, testable, and modular workflows that support production-grade analytics and machine learning use cases, with a focus on performance, data quality, and maintainability.
• Develop and iterate on time-series forecasting frameworks using approaches such as ARIMA/SARIMAX, ETS, MSTL, and machine learning-based models; evaluate performance through rigorous backtesting and continuously improve model accuracy and business applicability
• Experience building data visualizations and dashboards across platforms such as Tableau, ThoughtSpot, matplotlib, seaborn, plotly, or similar tooling.
• Strong project ownership: experienced operating to a roadmap, managing milestones and deliverables, and delivering high-quality work product in a timely manner
• Comfortable with autonomy and ambiguity, with a proactive orientation toward identifying and solving problems before they're fully defined
• Excellent written and verbal communication skills, including experience preparing materials for executive audiences

Summary

Klaviyo is looking for a Lead Data Science Analyst to join our GTM Strategic Analytics & Insights team. In this role, you will serve as a senior individual contributor at the intersection of advanced data science, AI/LLM-driven innovation, and Go-to-Market strategy. You will build and maintain sophisticated predictive and inferential models, conduct deep-dive statistical analyses, and develop AI-first solutions that unlock meaningful insights across the pre and post Sales Customer lifecycle.

The successful candidate will partner closely with GTM leadership to shape how Klaviyo understands, measures, and accelerates new business and customer outcomes; from pre-sales motion through onboarding, expansion and retention. You will operate with a strong bias toward AI-augmented workflows and bring a modern, LLM-aware approach to every analytical challenge.

The ideal candidate is intellectually curious, strategically minded, and energized by hard problems. They bring deep technical fluency across the full data science stack, a demonstrated ability to influence senior stakeholders through clear storytelling, and a genuine commitment to building AI-first solutions in a fast-moving SaaS environment.

How You Will Make a Difference

• Build and maintain advanced models: Build and maintain advanced predictive and time-series models: design, train, deploy, and monitor models across use cases such as demand forecasting, capacity planning, deal scoring, and customer propensity; incorporate seasonality, exogenous drivers, and backtesting frameworks to ensure accuracy and robustness
• Apply statistical rigor: lead deep-dive analyses leveraging regression, causal inference, hypothesis testing, correlation analysis, and other statistical methods to surface actionable signals from complex, large-scale datasets
• Develop AI/LLM-powered solutions: architect and implement AI-first analyses and tooling using large language models, prompt engineering, retrieval-augmented generation (RAG), and related techniques to automate insight generation, surface qualitative signals at scale, and augment team capabilities
• Own forecasting and decision systems: Own end-to-end forecasting and operational decision systems, including time-series demand forecasting, capacity planning models (e.g., Erlang-based staffing), and production pipelines that power GTM and Support planning workflows; ensure reliability, scalability, and business adoption of outputs
• Drive customer intelligence: develop and maintain prospect, deal health, archetype, and capacity models that inform GTM strategy, planning, and growth initiatives
• Define the measurement framework: identify, create, and steward benchmarks and metrics that meaningfully represent growth, engagement, and success outcomes
• Communicate with impact: distill complex analyses into clear, cohesive narratives with executive-ready materials that drive decisions at the senior leadership level
• Collaborate cross-functionally: partner with Systems & Engineering, GTM Operations, Rev Ops & Planning, Product, Business Intelligence, Data Science, and Finance to ensure analytical solutions are integrated, scalable, and trusted

Who You Are

• 6+ years of professional experience in an advanced analytics or data science role; SaaS experience strongly preferred
• Deep expertise in statistical inference and modeling, including supervised techniques (regression, classification, gradient boosting, decision trees) and unsupervised techniques (clustering, PCA, anomaly detection, topic modeling)
• Hands-on experience designing and deploying AI/LLM-based solutions, including prompt engineering, fine-tuning, RAG pipelines, or LLM-integrated analytics workflows; you approach new problems with an AI-first mindset
• Familiarity and experience with distributed coding projects, including using Git for code management.
• Advanced proficiency in Python (pandas, numpy, scikit-learn, xgboost, statsmodels, and LLM/AI libraries such as LangChain, OpenAI SDK, or HuggingFace) and SQL; working knowledge of DBT
• Own and scale end-to-end data pipelines, including orchestration with Airflow and transformation/modeling with dbt; design reliable, testable, and modular workflows that support production-grade analytics and machine learning use cases, with a focus on performance, data quality, and maintainability.
• Develop and iterate on time-series forecasting frameworks using approaches such as ARIMA/SARIMAX, ETS, MSTL, and machine learning-based models; evaluate performance through rigorous backtesting and continuously improve model accuracy and business applicability
• Experience building data visualizations and dashboards across platforms such as Tableau, ThoughtSpot, matplotlib, seaborn, plotly, or similar tooling.
• Strong project ownership: experienced operating to a roadmap, managing milestones and deliverables, and delivering high-quality work product in a timely manner
• Comfortable with autonomy and ambiguity, with a proactive orientation toward identifying and solving problems before they're fully defined
• Excellent written and verbal communication skills, including experience preparing materials for executive audiences

About the Role:

We are seeking a high-impact Machine Learning Scientist to join our integrated discovery team. In this role, leading from the bench, you will enable the development, validation and deployment of state-of-the-art ML models to generate the quantitative predictions necessary to drive drug discovery. Beyond technical mastery, you will serve as a core strategic partner to medicinal chemists, computational chemists, and biologists, building models that move programs efficiently toward Go/No-Go decision points and candidate nomination.  This role may be responsible for the management and development of individual team members.

Key Responsibilities:

• Lead the application of Large Language Models (LLMs), co-folding algorithms, and generative chemistry techniques to design novel chemical matter aimed at hitting key program milestones, such as establishing selectivity windows and optimizing drug-like properties
• ML lead on project teams, collaborating intimately with medicinal chemists to refine SAR and with structural biologists to integrate co-folding and structure-based insights into ML workflows
• Data-Driven Decision Making: Synthesize complex ML outputs into clear, actionable design hypotheses that cross-functional scientific stakeholders can use to make high-stakes program decisions
• May be responsible for management and development of internal team members

Required Qualifications:

• Ph.D. in Computational Chemistry, Computer Science, Machine Learning, or a related field
• Demonstrated expertise in statistics, probability theory, data modeling, machine learning algorithms, and the languages used to implement analytics solutions
• 4-7+ years of experience in a biotech or pharma setting performing ML support for small molecule drug discovery with clear evidence of impact on drug discovery programs
• Demonstrated success in a cross-functional environment, including biologists, structural biologists, medicinal and computational chemists, with specific examples of computational designs/algorithms/models that directly led to the achievement of program milestones
• Expert proficiency in Python and deep learning libraries (e.g., PyTorch, TensorFlow) is required. You must be able to build and maintain production-quality code and data pipelines

Preferred Qualifications:

• Proven experience with protein-ligand co-folding models (e.g.,Boltz, OpenFold, AlphaFold, etc) and the ability to integrate these structural insights into broader ML discovery pipelines
• Expertise fine-tuning existing models with internally generated structural biology and biology data
• Expert-level knowledge of deep learning frameworks, specifically for affinity prediction, ADMET modeling, and the application of LLMs in a biological or chemical context

Skills & Competencies:

• A demonstrated track record of innovation in the ML/AI space, including developing and validating new architectures or novel applications of existing models to solve complex drug discovery problems
• Demonstrated expertise using small molecule drug discovery ML/AI tools (AlphaFold, Boltz, OpenFold, ChemProp, DeepChem, Reinvent, etc)  
• Expert level coding for ML tasks including knowledge of key packages (RDKit, scikit-learn, numpy, pandas, pytorch, DeepChem, polars, PyG/DGL).
• Strong interpersonal and communications skills in the "why" behind a design to a diverse scientific audience
• Experience mentoring and developing teams