ABOUT SINGULAR GENOMICS

Singular Genomics is inventing at the forefront of genomics, one of the world’s fastest-growing industries. The commercially available G4® Sequencing Platform is a powerful, highly versatile benchtop genomic sequencer designed to produce fast and accurate results. In addition, the company is currently developing the G4X™ Spatial Sequencer, an upgrade to the G4, which will leverage Singular’s proprietary sequencing technology, applying it as an in situ readout for transcriptomics, proteomics and fluorescent H&E in tissue, with spatial context. Singular Genomics’ mission is to empower researchers and clinicians to advance science and medicine.

We foster a culture of creativity and technical excellence, both catalysts for innovation. We celebrate diversity, emphasize collaboration and, as we rapidly mature, we are constantly looking at ways we can do better for our people.

Our Headquarters are located on the Torrey Pines Mesa, in La Jolla, California at the center of the biotech hub. Our Manufacturing facility is in Sorrento Valley.

 

Position Summary:

As a Manufacturing Associate 2 on the chemistry team, you will be responsible for production of dye labeled NTPs, and other organic compounds, used in Singular’s NGS and Spatial technologies. We are seeking a self-driven individual who enjoys a unique opportunity to both routine work and help create manufacturing processes from ground up.

Responsibilities:

• Manufacture chemical compounds (nucleotides, linkers, triphosphates) using established synthesis schemes
• Document manufacture process on approved batch records, following good documentation practices
• Submit samples to internal and external QC departments
• Physically store inventory in lab at 4°C, -20°C, and -80°C storage conditions
• Work with manager and supply chain team to maintain adequate supply of raw materials
• Maintain laboratory instrumentation with the help of approved service contractors
  • LC-MS
  • HPLC (preparative and analytical)
  • Rotary evaporators
  • UV-Vis Spectrophotometers
• Work with facilities to address any safety issues in the lab
• Comfortable doing routine tasks with maximum precision and accountability.  
• Maintain excellent record keeping. Able to execute and improve batch records and SOPs.  
• Maintain lab and all documentation in line with a cGMP and cGDP production environment.  
• Maintain inventory of reagents, chemicals, and supplies.  
• Assist in day-to-day setup and running of lab operations. Maintain lab in accordance with all EH&S programs. Keep equipment operational by following protocols/SOPs. 
• Operates in fast-paced environment with rapidly shifting priorities. 
• Able to work while wearing full personal protective equipment (PPE) for the whole shift. 

Qualifications: 

• Bachelor of Science degree in a scientific field preferred.    
• At least 3-5 years manufacturing organic compounds in a GMP environment
• Experience with reverse phase, normal phase, and anion exchange chromatography
• GDP, GLP, GMP experience
• Familiar with 5S and other lean six sigma principles.

The estimated base salary range for this role based in the United States of America is: $68,640 - $86,400.  Additionally, this role is eligible for to receive equity as part of the compensation package. Compensation decisions are dependent on several factors including, but not limited to, an individual’s qualifications, location where the role is to be performed, internal equity, and alignment with market data. Should the level of the role change during the hiring process, the applicable salary range may be updated accordingly.

Singular Genomics is an equal opportunity employer. We celebrate diversity and are committed to creating an inclusive environment for all employees.

Singular Genomics is committed to working with and providing reasonable accommodations to job applicants with physical or mental disabilities. Applicants with a disability who require a reasonable accommodation for any part of the application or hiring process can provide their name and contact information to our Accommodations team at [email protected]. Your request will be responded to as soon as possible.