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Principal Engineer Jobs in Cambridge.

All active Principal Engineer positions in Cambridge. Verified listings, updated every few hours.

New engineering jobs daily on Telegram
Total jobs
77
positions indexed
New today
2
last 24 hours
Companies
18
actively hiring
Worldwide remote
0
from anywhere

How many Principal Engineer jobs in Cambridge are there right now?

There are 77 open Principal Engineer jobs in Cambridge on JobsRadar right now, from 18 companies hiring directly. 57 of them disclose pay, with a median of $172,500 a year and most offers between $170,000 and $198,550. 2 were added in the last 24 hours; the board was last refreshed on October 28, 2026 at 03:52 UTC.

Principal Engineer salary range in Cambridge

$170k 25th
$172.5k Median
$198.6k 75th
$163.7k
$257k
Box 25th–75th · whiskers 10th–90th Full range $209k – $374k · outliers off-axis
Based on 57 disclosed live listings
Updated Oct 27, 2026 from live listings
See full salary breakdown
role: Principal Engineer in: Cambridge Clear all
Sort Newest Top salary
Flagship Pioneering, Inc.
Principal Data Engineer
Flagship Pioneering, Inc.
⚡ Apply early Cambridge, MA USA Onsite $179,000–$236,000
● New 👁 Seen ✓ Applied 8h ago
VT
Principal Data Engineer
Vesalius Therapeutics
⚡ Apply early Cambridge, MA Onsite $179,000–$236,000
● New 👁 Seen ✓ Applied 8h ago
Nanopath
Electrical Engineer (Senior/Staff/Principal)
Nanopath
⚡ Apply early Cambridge, MA Onsite
● New 👁 Seen ✓ Applied 1d ago
Draper
Distinguished System Requirements Engineer
Draper
⚡ Apply early Clearfield, UT Onsite $100,000–$275,000
● New 👁 Seen ✓ Applied 2d ago
Flagship Pioneering, Inc.
Senior / Principal Data Infrastructure Engineer
Flagship Pioneering, Inc.
⚡ Apply early Cambridge, MA USA Onsite $165,000–$209,000
● New 👁 Seen ✓ Applied 5d ago
Draper
Principal Mission Critical Software Engineer
Draper
⚡ Apply early Cambridge, MA Onsite $95,000–$245,000
● New 👁 Seen ✓ Applied 6d ago
LS
Staff / Principal Research Engineer, AI Safety Mitigations
Lila Sciences
⚡ Apply early Cambridge, MA USA; London, UK;... Onsite $224,000–$336,000
● New 👁 Seen ✓ Applied 6d ago
LS
Staff / Principal Security Engineer, AI Safety and Security
Lila Sciences
⚡ Apply early Cambridge, MA USA; London, UK;... Onsite $192,000–$306,000
● New 👁 Seen ✓ Applied 6d ago
LS
Principal Engineer, AI Security
Lila Sciences
⚡ Apply early Cambridge, MA USA Onsite $252,000–$374,000
● New 👁 Seen ✓ Applied 6d ago
LS
Principal Machine Learning Engineer, Applied AI
Lila Sciences
⚡ Apply early Cambridge, MA USA; San Francis... Onsite $252,000–$336,000
● New 👁 Seen ✓ Applied 6d ago
LS
Principal Network Engineer
Lila Sciences
⚡ Apply early Cambridge, MA USA Onsite $204,000–$272,000
● New 👁 Seen ✓ Applied 6d ago
LS
Principal Software Engineer, App
Lila Sciences
⚡ Apply early Cambridge, MA USA; San Francis... Onsite $204,000–$348,000
● New 👁 Seen ✓ Applied 6d ago
LS
Principal Software Engineer, Instrument Simulations
Lila Sciences
⚡ Apply early Cambridge, MA USA Onsite $204,000–$272,000
● New 👁 Seen ✓ Applied 6d ago
LS
Staff/ Principal Software Engineer, Scientific System of Record
Lila Sciences
⚡ Apply early Cambridge, MA USA; San Francis... Onsite $204,000–$310,000
● New 👁 Seen ✓ Applied 6d ago
LS
Staff / Principal Automated Systems Engineer
Lila Sciences
⚡ Apply early Cambridge, MA USA Onsite $163,400–$228,000
● New 👁 Seen ✓ Applied 6d ago
LS
Principal Software Engineer, Applied AI
Lila Sciences
⚡ Apply early Cambridge, MA USA; San Francis... Onsite $204,000–$310,000
● New 👁 Seen ✓ Applied 6d ago
Draper
Principal Hardware Instrument Engineer
Draper
⚡ Apply early Cambridge, MA Onsite $95,000–$245,000
● New 👁 Seen ✓ Applied 6d ago
Draper
Principal Power Electronics Engineer
Draper
⚡ Apply early Cambridge, MA Onsite $82,300–$245,000
● New 👁 Seen ✓ Applied 1w ago
Graphcore
Principal Hardware System Test Engineer
Graphcore
⚡ Apply early Bristol, UK; Cambridge, UK Onsite
● New 👁 Seen ✓ Applied 1w ago
Draper
Principal Digital ASIC Design Engineer
Draper
⚡ Apply early Cambridge, MA Onsite $95,000–$275,000
● New 👁 Seen ✓ Applied 1w ago
GV
Principal AI Software Engineer
GE Vernova
⚡ Apply early Niskayuna Onsite $145,400–$242,500
● New 👁 Seen ✓ Applied 1w ago
RTX
Principal Signal Processing / Controls Engineer
RTX
⚡ Apply early US-MA-CAMBRIDGE-BBN01 ~ 10 & 5... Hybrid
● New 👁 Seen ✓ Applied 2w ago
Draper
Principal Hardware Electronic Engineer
Draper
⚡ Apply early Cambridge, MA Onsite $95,000–$245,000
● New 👁 Seen ✓ Applied 2w ago
CM
Principal Analytics Engineer
Cambridge Mobile Telematics
⚡ Apply early Cambridge, MA Onsite $169,700–$212,100
● New 👁 Seen ✓ Applied 2w ago
CM
Principal Machine Learning Engineer
Cambridge Mobile Telematics
⚡ Apply early Cambridge, MA Onsite $198,300–$247,900
● New 👁 Seen ✓ Applied 2w ago

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Frequently asked questions

How many Principal Engineer jobs in Cambridge are open right now?
77 Principal Engineer jobs in Cambridge are open across 18 companies, as of October 28, 2026.
What do Principal Engineer jobs in Cambridge pay?
Across the 57 Principal Engineer jobs in Cambridge that disclose pay, the median is $172,500 a year, and the middle half of offers falls between $170,000 and $198,550.
Which companies are hiring Principal Engineer jobs in Cambridge?
Flagship Pioneering, Inc., Vesalius Therapeutics, Nanopath, Draper and Lila Sciences are among the 18 companies currently hiring Principal Engineer jobs in Cambridge.
How current are these listings?
Every listing comes straight from the employer’s own careers system and is re-checked three times a day. This page was last updated on October 28, 2026 at 03:52 UTC.

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