About this Sr Director/Executive Director, Pharm Science Technical Lead role at BridgeBio Pharma
Mavericks Wanted
When was the last time you achieved the impossible? If that thought feels overwhelming, you might want to pause here, but if it sparks excitement...read on
In 2015, we pioneered a “moneyball for biotech” approach, pooling projects and promising early-stage research from academia together under one financial umbrella to reduce risk and unleash innovation. This model allows science and small teams of experts to lead the way. We build bridges to groundbreaking advancements in rare disease, and develop life-changing medicines for patients with unmet needs as fast as humanly possible.
Together we define white space, push boundaries, and empower people to solve problems. If you're someone who defies convention, join us and work alongside some of the most respected minds in the industry. Together, we'll ask "why not?" and help reengineer the future of biopharma. At BridgeBio, we value curiosity and experimentation—including the ethical & thoughtful use of AI to improve clarity, speed, and quality of work.
What You’ll Do
The Pharmaceutical Sciences Team Lead (PSTL) is a senior scientific and strategic leadership role responsible for advancing pharmaceutical development and CMC (Chemistry, Manufacturing, and Controls) strategy across clinical and commercial-stage programs. This individual will lead cross-functional pharmaceutical sciences activities spanning formulation development, analytical development, process development, manufacturing, technology transfer, regulatory submissions, and lifecycle management. The role requires a proven leader with deep expertise in pharmaceutical development, strong regulatory and quality knowledge, and the ability to lead high-performing scientific teams in a fast-paced, matrixed environment. The PSTL will serve as a key contributor to corporate development strategy and represent Pharmaceutical Sciences in executive governance, regulatory interactions, and external partnerships.
Responsibilities
- Lead high-performing, collaborative, and accountable Pharmaceutical Sciences teams across multiple functional disciplines.
- Establish and drive organizational priorities, resource plans, and development goals aligned with corporate objectives.
- Identify program risks proactively and implement mitigation strategies to maintain timelines and deliverables.
- Provide scientific leadership for formulation development, analytical development, process development, manufacturing, and technology transfer.
- Partner with Non-clinical, Clinical, Regulatory, and Commercial organizations to ensure alignment on development priorities and execution.
- Represent Pharmaceutical Sciences in governance committees and executive reviews.
- Influence senior leadership decisions through data-driven scientific and operational recommendations.
- Collaborate with Regulatory Sciences and Regulatory Affairs on CMC strategy, risk mitigation, and agency responses.
- Represent Pharmaceutical Sciences in interactions with global health authorities and regulatory inspections, as needed.
- Participate in due diligence activities, external scientific collaborations, and business development evaluations.
- Build strong relationships with external partners, vendors, and industry organizations.
- Implement scalable systems, processes, and metrics to improve development efficiency and execution quality.
- Foster an inclusive and performance-oriented culture that embodies company leadership values and behaviors.
Where You’ll Work
This role requires in-office collaboration 2-3x per week in our San Francisco Office and travel, as needed
Who You Are
- PhD or equivalent advanced degree in Pharmaceutical Sciences, Chemistry, Chemical Engineering, Biochemistry, or related scientific discipline preferred.
- 15+ years of progressive pharmaceutical or biotechnology industry experience, including significant leadership responsibility in Pharmaceutical Sciences, CMC, or Technical Operations.
- Experience leading multidisciplinary scientific teams in matrixed global organizations.
- Strong knowledge of pharmaceutical development, manufacturing, analytical development, regulatory expectations, and quality systems.
- Experience managing external manufacturing and development partners (CMOs/CDMOs/CROs).
- Strategic thinker with strong scientific and operational acumen.
- Exceptional communication and influencing skills with executive presence.
- Proven ability to drive alignment across complex cross-functional organizations.
- Strong decision-making and problem-solving capabilities in dynamic development environments.
- Prior experience in NDA/MAA submissions and regulatory approvals.
- Experience supporting commercial manufacturing and lifecycle management activities.
- Familiarity with global supply chain strategy and technical operations.
- Experience in both large pharmaceutical and emerging biotech environments preferred.
- Travel, as needed
As a global company, our comprehensive benefits may vary based on location. We have high expectations for our team members. We make sure those working hard for patients are rewarded and cared for in return.
For BridgeBio Full-Time U.S Based Roles:
Financial & Rewards
- Market-leading compensation
- 401(k) with employer match
- Employee Stock Purchase Program (ESPP)
- Pre-tax commuter benefits (transit and parking)
- Referral bonus for hired candidates
- Subsidized lunch and parking on in-office days
Health & Well-Being
- 100% employer-paid medical, dental, and vision premiums for you and your dependents
- Health Savings Account (HSA) with annual employer contributions, plus Flexible Spending Accounts (FSA)
- Fertility & family-forming benefits
- Expanded mental health support (therapy and coaching resources)
- Hybrid work model with flexibility
- Flexible, “take-what-you-need” paid time off and company-paid holidays
- Comprehensive paid medical and parental leave to care for yourself and your family
Skill Development & Career Paths:
- People are part of our growth and success story - from discovery to active drug trials and FDA pipelines, there are endless opportunities for skill development and internal mobility
- We provide career pathing through regular feedback, continuous education and professional development programs via LinkedIn Learning, LifeLabs, & BetterUp Coaching
- We celebrate strong performance with financial rewards, peer-to-peer recognition, and growth opportunities
