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About this Site Reliability Engineer role at Prolaio

Prolaio · Onsite · Chicago, IL

Who Are We?

Prolaio believes that continuous learning and collaboration can make a significant difference in how heart care is administered. We are creating smarter ways to address heart disease and heart risks by uniting patients, care teams, and researchers on a secure, technology-enabled platform that drives clinical innovation and offers a path towards better patient outcomes.

This is precision cardiology, and we know it’s within reach.

What Will You Do?

The Overview

The Site Reliability Engineer will ensure that Prolaio’s cardiovascular data platform reliably captures, transports, and delivers continuous biosensor data from participants to the clinical researchers and trial sponsors who depend on it. In this role, you will build and operate the monitoring, service level objectives, incident response, and automation needed to keep critical data flows healthy, identify failures before they impact studies, and ensure that device downtime never goes unnoticed simply because a shipment record says a device was delivered.

This role is ideal for a self-starter who thrives at the intersection of software reliability, connected devices, and clinical data. You will investigate incidents across the full participant-to-platform stack, combining service telemetry with device data and participant reports to determine whether an issue originated with the hardware, phone, firmware, mobile application, connectivity, or the platform itself. You will turn those investigations into durable improvements, automating manual checks, strengthening observability, reducing operational toil, and building the reliability practices that keep Prolaio’s clinical data complete and trustworthy at scale.

The Specifics

  • Build monitoring that treats missing data as a failure rather than a quiet day — freshness, volume and quality checks that verify delivery from outside the system instead of trusting a job's exit code.
  • Define and maintain SLIs, SLOs and error budgets for customer-facing data services, and report attainment honestly, including when the news is bad.
  • Join the on-call rotation, run incident response, and write blameless postmortems that produce owned follow-up actions.
  • Investigate device failures end to end: correlate discharge curves, Bluetooth disconnects and wear detection against the participant's complaint, and establish or exonerate each candidate cause on evidence.
  • Treat the fleet as a population — failure rates per device-month, clustering by build lot, firmware version or site — rather than as a queue of individual tickets.
  • Close the loop. When an analysis cannot reach a verdict, name the missing metric or threshold and route it back into the diagnostics pipeline so the next case is answerable from telemetry alone.
  • Build reliability tooling in Python and SQL on BigQuery, and keep monitors and probes defined as code rather than configured by hand.
  • Retire manual checks by automating them. Operational toil should shrink quarter over quarter, not accumulate.

Why Prolaio?

  • Impactful Work: You will join in the fight against heart failure (HF) and hypertrophic cardiomyopathy (HCM) with the goal of extending and saving the lives of our patients while also being at the forefront of changing the healthcare industry through technology.
  • Innovative Environment: You will be part of an organization doing something that’s never been done before.
  • Professional Growth: You will join a growing team and have a substantial impact on our daily and future operations with the opportunity to continuously learn and grow.
  • Collaborative Team: You will be part of a team of collaborative, curious, and committed individuals focused on the collective good, inclusiveness, scientific excellence, and advancing digital health for cardiology.

Who You Are?

  • Bachelor's degree in Electrical Engineering, Computer Engineering, Computer Science, Biomedical Engineering or a related technical field, or equivalent practical experience.
  • 2–5 years in reliability engineering, production operations, hardware or systems test, field failure analysis, or data engineering — in a role where you were accountable for something that had to keep working.
  • Working SQL and Python: able to pull a dataset, characterize it, and defend the query behind a number.
  • Experience with a cloud data platform (Google Cloud and BigQuery preferred; AWS or Azure equivalents are fine).
  • Ability to write up a technical investigation clearly — what was observed, what was ruled out and how, and what remains unknown.

Additional Qualifications (Nice to Haves)

  • Hands-on exposure to Bluetooth Low Energy (GATT services and characteristics, connection intervals, pairing and bonding, disconnect behaviour), Wi-Fi or cellular data standards — and how each one fails in the field rather than how it is specified to behave.
  • Battery and power behaviour: discharge characterisation, charge-state interpretation, and telling a measurement artefact from a real capacity defect.
  • Formal reliability method — FMEA and risk priority numbers, FRACAS practice, and standards such as IEC 60812 or ISO 13485.
  • Observability tooling (Datadog, Grafana or similar) and synthetic monitoring.
  • Android device telemetry, mobile application diagnostics, or embedded firmware experience.
  • Prior work in medtech, digital health, clinical trials or another regulated, patient-facing environment.

Why You’ll Love Working Here

  • Meaningful Compensation: Competitive salary, performance bonus, and equity so you can share in what we build.
  • Great Health Coverage: Medical, dental, and vision plans with multiple options and strong company contributions.
  • Flexible Spending Perks: HSA, FSA, commuter benefits, and a $1,200 annual Lifestyle Spending Account to support wellness, commuting, family needs, and more.
  • Time to Recharge: Generous paid time off, sick leave, and company holidays.
  • Family-First Benefits: Paid parental leave, caregiver leave, and support for growing families.
  • Security & Peace of Mind: Company-paid life insurance and short- and long-term disability coverage.
  • Plan for the Future: 401(k) plan to help you build long-term financial security.
  • Care When You Need It: Easy access to telehealth and optional supplemental coverage for life’s unexpected moments.

Starting Salary is at $ 118,000.00 (Exact Compensation may vary based on skills, experience, and location)

 

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How this SRE salary compares

This role pays $118,000/yr — below the typical range for SRE roles.

$115,600 median $140,700 $191,200

Typical range $119,650–$170,000/yr, from 17 comparable SRE listings on JobsRadar (pay annualized to USD). See SRE salary insights →

About Prolaio

Prolaio is a healthcare startup focused on improving heart care through a connected platform that uses near real-time data and AI to help patients, clinicians, and researchers manage cardiovascular conditions like heart failure and hypertrophic cardiomyopathy (HCM). 

See all jobs at Prolaio →

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