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About this Senior Software Engineer - Instrument role at Nuclera

Nuclera · Onsite · Cambridge, England, United Kingdom

Nuclera is a venture-backed, founder-driven biotech company headquartered in Cambridge, UK with significant operations in Boston, USA. Our purpose is to improve human health by making proteins accessible to life science researchers around the world. 

In 2024, we launched eProtein Discovery™ - a breakthrough protein expression, characterization, and purification platform, consisting of cloud-based software and a lab-based instrument (with proprietary cartridges and consumables). Since then, we have established a growing installed base in North America, Europe and Asia, receiving numerous awards and customer accolades.

As a key player in a small engineering team, you will support the next stage of Nuclera’s growth through:

  • New Products - Contributing to development of a new product platform and its support tools. 
  • Installed Base Support - Sustaining and being the internal expert and primary point of contact for manufacturing and field support issues relating to current generation Instrument.

Over time (6-12 months), your skills and responsibilities will broaden to include other software languages and technologies. This may also extend to electronics and PCB design.

About the role

Software Development

  • Full lifecycle development and release management for prototypes, products and support tools.

Project Management 

  • Planning: Providing plans covering tasks, dependencies, effort, cost and resource allocation.
  • Risk Management: Supporting risk identification, evaluation and choice of risk response strategies.
  • Execution & Self-Monitoring: Progress according to agreed priorities and plans.  Devise appropriate responses to problems and issues. Track and report own progress (deliverables, adherence to schedules, actual spend vs budget, etc.)

Quality Management 

  • Progress according to agreed priorities and plans.  Devise appropriate responses to problems and issues. Track and report own progress (deliverables, adherence to schedules, actual spend vs budget, etc.)

Requirements

Essential:

  • Bachelors’ Degree in Software Engineering, Computer Science or similar.
  • 5+ years of full lifecycle development for multi-technology products developed to rigorous standards. Life science equipment / medical device equipment experience desired.
  • Programming Languages: C for STM32 and Raspberry Pi Pico 2, python 3, Bash 
  • Operating Systems / Frameworks: Embedded Linux / Yocto, Docker 
  • Development Environment: Git / Gitlab / CI/CD, Jira 
  • Software Quality: coding standards/static analysis, code/design review, testing - unit, integration, hardware-in-the-loop 
  • Technologies: real-time control & monitoring (motion / mechanism functions & temperature control) embedded systems / electronics, LAN networking  
  • Strong initiative, problem-solving, task prioritization, and end-to-end execution / completion.
  • Effective relationship management, cross-functional teamwork, clear documentation, and presentation skills.
  • Current UK driving licence. Willing and able to occasionally travel nationally / internationally on business as required.

Desirable:

  • Programming Languages: C for SAM 4S / SAM D20, Java, Javascript / React
  • Operating Systems / Frameworks: Torizon, PyQt 6, RTOS
  • Development Environment: VS Code, Claude AI
  • Software Quality: Software Architecture / UML, Design Controls, Stage-Gate Development, Problem solving (DMAIC, 8D) 
  • Technologies: Microfluidics, Optics / Image Processing, Machine Learning / Neural Networks, Cybersecurity,  PCB Design (Altium), GUI Design

Benefits

What we offer: 

In addition to competitive salaries, we offer a range of benefits including:

  • Company bonus scheme of 5%
  • Share option incentive scheme
  • Life insurance
  • Private medical insurance and cash plan
  • 25 days' annual leave + Bank Holidays
  • Enhanced employer's pension contributions
  • Enhanced maternity and paternity Leave
  • Investment in professional development and learning
  • Fresh fruit, tea, coffee, and snacks in the office
  • Organised summer events for staff
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About Nuclera

Nuclera mission is to accelerate discovery by providing researchers rapid, easy access to the highest-quality functional proteins essential for drug discovery research. Our eProtein Discovery™ benchtop system combines unique cell-free expression systems, novel digital microfluidics, and robust screening data to empower scientists to perform multiplex protein screening, characterization, and small-scale expression in-house

By providing clear guidance on which protein has the best chance of success from the start, eProtein Discovery™ reduces the time, cost, and uncertainty traditionally associated with protein expression and purification. Researchers can generate soluble, purified proteins, including challenging membrane proteins, for downstream functional testing in under 48 hours, significantly accelerating workflows compared with months-long cell-based methods.

Founded in 2013 by PhD students at the University of Cambridge, Nuclera has expanded its presence to Cambridge, UK, and Boston, MA. With a team of over 100 employees, we remain dedicated to our vision of making proteins easily accessible and contributing to advancements in human health.

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