At Regeneron, we use science and innovation to develop life-changing medicines for people with serious diseases. We are seeking a Sr Associate Scientist to join our Product Biochemistry team, on-site in Tarrytown, NY. In this role, you will support late-stage development (Phase II through commercialization) of biologics, developing and deploying analytical methods and purification strategies, enriching and characterizing product variants, and helping onboard new technologies that deepen product understanding and improve processes across the pipeline.

This position offers the opportunity to bring scientific creativity, efficiency, and flexibility to a fast-paced, science-driven organization making a meaningful difference to patients worldwide.

When & where:

• Shift Requirements: Full-time, standard business hours
• Location: On-site in Tarrytown, NY
• Flexibility & travel: Minimal to no travel; on-site presence required to support laboratory operations

What you'll do:

• Develop analytical methods and purification protocols to support extended characterization of therapeutic proteins and gene therapy vectors
• Conduct biochemical/biophysical characterization to support development, regulatory submissions, and commercialization
• Apply DOE, advanced statistics, and risk assessments to evaluate and optimize methods and processes
• Design and execute experiments to enrich, purify, and characterize size/charge variants, complexes, and high-concentration formulations
• Independently operate U/HPLCs and AKTA FPLCs, and perform capillary-based electrophoresis
• Integrate learnings from internal data and external literature to make science-based study design recommendations
• Author high-quality technical documents (protocols, reports, memos), contribute to regulatory sections and publications, and ensure timely documentation of experiments in accordance with established SOPs and guidelines
• Document experiments, results, and findings in the electronic laboratory notebook, and present work at group and department meetings
• Maintain instruments, troubleshoot instrumental/experimental problems, order/maintain supplies, and improve lab/data workflows within your area of expertise

The environment and physical rhythms of this role:

• This is a hands-on, on-site laboratory role requiring independent operation of specialized analytical instrumentation and the ability to manage multiple priorities in a fast-moving R&D environment.
• Flexibility to thrive in a fast-paced, team environment while also working independently across multiple projects, and to mentor others while contributing to a safe, efficient, and inclusive lab environment, is required.

Let's find out if we're a fit:

Must-haves:

• BS/MS in Biochemistry, Biophysics, Engineering, or a related field, with 4-6+ years of relevant industry experience
• Strong lab skills in protein separation, purification, and tangential flow filtration (TFF), and skills in protein/product identification using mass spectrometry
• Excellent oral and written communication skills and evidence of teamwork
• Strong initiative to complete tasks, learn new technologies, and demonstrate a commitment to continuous learning
• Ability to communicate clearly, transparently, and in a timely manner with key stakeholders

Preferred / nice-to-haves:

• Technical proficiency in automated FPLC and/or HPLC (SEC, IEX, affinity), electrophoresis (capillary or microchip, SDS-PAGE, western blots), spectroscopy, and light scattering
• Fundamental understanding of protein structure/function, mass spectrometry, and immunology/immunogenicity
• Experience working in the biopharmaceutical industry

Thrive today. Grow tomorrow.

• Student Loan Paydown program & Tuition Reimbursement
• Family Care Benefits
• Relocation Assistance
• Inclusion, Culture and Well-Being programs (including physical & mental health)

Does this sound like you? Apply now to take your first step towards living the Regeneron Way! We are committed to building a workplace with an inclusive culture. Regeneron is an equal opportunity employer and all  qualified applicants will receive consideration for employment without regard to race, color, religion or belief (or lack thereof), sex, sexual orientation, gender identity or expression, gender reassignment, marital or civil partnership status, civil status, pregnancy or parental status, age, disability, nationality, citizenship status, ethnic or national origin, membership of the Traveler community, familial status, genetic information, military or veteran status, or any other characteristic protected under applicable law. Where required, we will provide reasonable accommodation to applicants with known disabilities or chronic illnesses during the recruitment process, unless such accommodation would impose undue hardship.

Where necessary, we disclose salary ranges for roles in all countries in which we operate.  The final offer will be determined within the relevant range based on the country of employment, specific role level, and your skills and experience. In some countries, collective bargaining agreements (CBAs) may apply and influence certain elements of pay or benefits.  Regeneron offers a competitive and comprehensive total rewards package which may include, depending on country and role: annual bonuses or other incentive plans, equity awards, pension or retirement benefits, 401(k) company match, health and wellness programs, fitness centers, insurance benefits (e.g. medical, dental, vision, life and disability), paid time off, and family support benefits. For additional information about Regeneron benefits in the U.S., please visit https://careers.regeneron.com/en/working-at-regeneron/total-rewards/. For other locations, additional information will be provided during the recruitment process.  If you have any questions, please speak with your recruiter. 

Please be advised that at Regeneron, we believe we do our best work when we are together. For that reason, many roles are required to be performed on‑site. Please speak with your recruiter and hiring manager for more information about on‑site expectations for your role and location.

As part of the recruitment process, certain background checks may be conducted in accordance with the laws of the country where the position is based. The purpose of such checks is to verify certain information prior to the commencement of employment such as identity, right to work and educational qualifications.

For jobs in Canada: this posting is for an existing position.

Salary Range (annually)